CN104352716A - Composition for preventing/treating sheep urolithiasis and preparation method and applications thereof - Google Patents

Composition for preventing/treating sheep urolithiasis and preparation method and applications thereof Download PDF

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CN104352716A
CN104352716A CN201410649161.3A CN201410649161A CN104352716A CN 104352716 A CN104352716 A CN 104352716A CN 201410649161 A CN201410649161 A CN 201410649161A CN 104352716 A CN104352716 A CN 104352716A
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preventing
sheep
compositions
bicarbonate
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CN104352716B (en
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李广
刘璐
付明哲
周占琴
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Northwest A&F University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a composition for preventing/treating sheep urolithiasis and a preparation method and applications thereof. The composition comprises the following components in parts by mass: 20-40 parts of sunflower plate, 10-30 parts of cushaw stems, 10-30 parts of plantain, 1-10 parts of yam rhizome, 1-15 parts of desmodium, 5-10 parts of ammonium salt, 10-30 parts of ammonium bicarbonate, and 5-10 parts of magnesium oxide. The composition disclosed by the invention has the functions of reducing fever and causing diuresis, expelling wind and excreting damp, and removing pattogenic heat from the blood and toxic material from the body, and can improve the pH value of urine, so that uric acid calculus is dissolved. The composition can be used as an additive directly taken by sheep, and through the daily feeding of the composition, the urolithiasis of drylot feeding sheep is prevented and treated.

Description

A kind of composition and method of making the same of preventing/treating sheep urinary calculus and application
Technical field
The invention belongs to sheep urinary calculus preventing/treating technical field, relate to a kind of composition and method of making the same and application of preventing/treating sheep urinary calculus.
Background technology
Urinary calculus is that the paracrystalline concretion of inorganic or organic salt (as calculus, JISHI or volume crystallization etc.) in urinary tract stimulates, a kind of disease of damage urinary tract mucosa and hemorrhage, the inflammation that causes and obstruction.This is a kind of frequently-occurring disease of animal urinary system, especially since China carries out Closing grazing, under drylot feeding condition, urinary calculi in sheep incidence rate presents obvious ascendant trend, at the northern area of China sheep calculus average attack rate 15.68%, indivedual area is up to 32.36%, case fatality rate reaches 92.9%, and sheep uriasis brings huge economic loss to vast raiser.
The sheep urinary calculus initial stage cause suffer from that sheep spirit is depressed, appetite reduces, ruminate weaken, baa of moan is named, eye conjunctiva is pale, heart rate accelerates, urination time prolongation, frequent micturition, hypourocrinia or be drop-wise outflow.Subsequently, suffer from sheep body temperature and be elevated to 39.5 DEG C ~ 41.0 DEG C, strongly exert duty, again and again lift tail, hind leg flexing is diverged, and has obvious colic symptoms.Palpation bladder finds, bladder height expands, nervous, and pressing is without urine discharge, ureter and glans penis enlargement, hyperemia.The sleeping ground of later stage sick sheep does not rise and with poisoning symptom.
Sheep urinary calculus main harm ureter, bladder and kidney, comparatively obvious at ureteral " S " crooked position; Intravesical especially can be condensed into bulk or coralliform at bladder neck place, and powder pinched into by finger stone roller, and some fillings of bladder, wall thickening, mucosa is purplish red often erosion or ulcer, inside has the sand grains sample granule differed in size, and hands grinds then broken; Renal pelvis has ecchymosis, kidney enlargement, tangent plane succulence, and renal pelvis inner product has milky granule agglutinator.
The generation of sheep urinary calculus is relevant with the factor such as feedstuff, water quality.The proportioning of concentrate is unreasonable or concentrate ratio is higher, and particularly content of mineral substances causes the generation of urinary stone compared with Gao Shiyi.By measuring urinary stone specimen infared spectrum, finding its calculus type mainly based on calcium oxalate and calcium oxalate+podolite, accounting for 83.2%; Present high phosphorus, high fluorine, low magnesium, low calcium, low chlorine, low ferrum phenomenon in sick sheep blood, the content in this and local feedstuff, water and soil presents conforming Changing Pattern.
Sheep urinary calculus mainly takes comprehensive preventive health measures, comprises the proportioning of concentrate and the adjustment of concentrate coarse fodder ratio, reduces phosphorus, fluorine, magnesium, calcium, improves roughage ratio, occurs to reduce primary disease.Western medical treatment is with relieving spasm to stop pain, and infection control, diuresis and expelling stone is main.
Summary of the invention
The problem that the present invention solves is the composition and method of making the same and the application that provide a kind of preventing/treating sheep urinary calculus, and clearing away heat and promoting diuresis, can improve urine pH, and urate calculus is dissolved; By being mixed in feedstuff the generation of feeding and reaching prevention and therapy drylot feeding sheep urinary stone.
The present invention is achieved through the following technical solutions:
A compositions for preventing/treating sheep urinary calculus, according to the mass fraction, comprises following component:
Receptaculum Helianthi 20 ~ 40 parts, Caulis Cucurbitae 10 ~ 30 parts, Herba Plantaginis 10 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 1 ~ 10 part, Herba Lysimachiae 1 ~ 15 part, ammonium salt 5 ~ 10 parts, bicarbonate 10 ~ 30 parts, magnesium oxide 5 ~ 10 parts.
Described compositions, according to the mass fraction, comprises following component:
Receptaculum Helianthi 20 ~ 30 parts, Caulis Cucurbitae 10 ~ 20 parts, Herba Plantaginis 10 ~ 20 parts of, Rhizoma Dioscoreae Septemlobae 5 ~ 8 parts, Herba Lysimachiae 5 ~ 10 parts, ammonium salt 5 ~ 10 parts, bicarbonate 15 ~ 24 parts, magnesium oxide 5 ~ 8 parts.
Described compositions, according to the mass fraction, comprises following component:
Receptaculum Helianthi 30 ~ 40 parts, Caulis Cucurbitae 20 ~ 30 parts, Herba Plantaginis 20 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 8 ~ 10 parts, Herba Lysimachiae 8 ~ 10 parts, ammonium salt 5 ~ 10 parts, bicarbonate 15 ~ 25 parts, magnesium oxide 5 ~ 8 parts.
Described compositions, according to the mass fraction, comprises following component:
Receptaculum Helianthi 20 ~ 25 parts, Caulis Cucurbitae 15 ~ 20 parts, Herba Plantaginis 10 ~ 15 parts of, Rhizoma Dioscoreae Septemlobae 5 ~ 10 parts, Herba Lysimachiae 5 ~ 10 parts, ammonium salt 5 ~ 8 parts, bicarbonate 20 ~ 24 parts, magnesium oxide 5 ~ 8 parts.
Described compositions, according to the mass fraction, comprises following component:
Receptaculum Helianthi 25 parts, Caulis Cucurbitae 20 parts, Herba Plantaginis 15 parts of, Rhizoma Dioscoreae Septemlobae 5 parts, Herba Lysimachiae 5 parts, ammonium salt 7 parts, bicarbonate 15 parts, magnesium oxide 8 parts.
Described ammonium salt is ammonium chloride, and bicarbonate is sodium bicarbonate.
A preparation method for the compositions of preventing/treating sheep urinary calculus, comprises following operation:
Each component is taken: Receptaculum Helianthi 20 ~ 40 parts, Caulis Cucurbitae 10 ~ 30 parts, Herba Plantaginis 10 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 1 ~ 10 part, Herba Lysimachiae 1 ~ 15 part, ammonium salt 5 ~ 10 parts, bicarbonate 10 ~ 30 parts, magnesium oxide 5 ~ 10 parts by following mass parts;
To pulverize after each component mixing or pulverize rear mixing, gained powder be the compositions of preventing/treating sheep urinary calculus.
Described ammonium salt is ammonium chloride, and bicarbonate is sodium bicarbonate;
Also by gained powder according to 1.0 ~ 3.0% mass ratio be mixed in sheep hurdle feedstuff.
The application of compositions in the medicine preparing preventing/treating sheep urinary calculus or feed additive of described preventing/treating sheep urinary calculus.
Described compositions is that described sheep is meat type, hair meat dual-purpose type or meat hair dual-purpose type in the application of preparation drylot feeding in sheep feedstuff.
Compared with prior art, the present invention has following useful technique effect:
The compositions of preventing/treating sheep urinary calculus provided by the invention, with Receptaculum Helianthi, Caulis Cucurbitae and Herba Plantaginis for principal agent Yi Rhizoma Dioscoreae Septemlobae, Herba Lysimachiae are for helping medicine, and be aided with ammonium salt, bicarbonate, magnesium oxide carry out synergism, said composition has the effect of clearing away heat and promoting diuresis, expelling wind and removing dampness, removing pathogenic heat from blood and toxic substance from the body, and can urine pH be improved, urate calculus is dissolved.Said composition can be taken directly to sheep as additive, feeds by daily raising the generation reaching prevention and therapy feeding sheep urinary stone.
The compositions of preventing/treating sheep urinary calculus provided by the invention, had both had the clearing away heat and promoting diuresis of middle medicinal herbs, and the collaborative neutralization having compound, reaches the treating both the principal and secondary aspects of a disease to sheep urinary stone again; Existing therapeutical effect also has protection effect.Wherein, Receptaculum Helianthi clearing away damp-heat, diuresis, by wind; Caulis Cucurbitae: suppressing the hyperactive liver and easing the stomach, the meridian dredging, sharp blood vessels, kidney nourishing water; Herba Plantaginis: clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Rhizoma Dioscoreae Septemlobae: expelling wind and removing dampness; Herba Lysimachiae: clearing away heat and promoting diuresis, wind-expelling pain-stopping, hemostasia and promoting granulation.And sodium bicarbonate/ammonium chloride: there is collaborative diuresis, can strongly and rapidly in and gastric acid, blood plasma intracellular bicarbonate salinity can be made to raise, blood pH value rises, free carbonic acid hydrion can be impelled to discharge with urine, urine pH is raised in alkalescence, urate calculus is dissolved.Magnesium oxide: have antiacid laxative effective, suppresses and alleviates hyperchlorhydria, in and gastric acid effect by force and slowly lasting, with sodium bicarbonate, there is strong synergism.
The compositions of preventing/treating sheep urinary calculus provided by the invention, the ratio according to 1.0% ~ 2.0% is mixed in sheep (meat type) daily feedstuff, feeds 3 months, and other conditions are constant.Be 0 through observing and detecting uriasis sickness rate.Ratio according to 2.0% ~ 3.0% is mixed in the daily feedstuff of sheep, feeds 3 months, and occur without epidemic disease through observing flock of sheep, without uriasis, the ram just suffering from uriasis before feeding is eased and fully recovers.
The composition and method of making the same of preventing/treating sheep urinary calculus provided by the invention, its raw material is easy to get, without any side effects; And have that preparation is simple, the advantage of low in raw material price, especially prophylactic treatment is effective, is easy to popularize.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail, and the explanation of the invention is not limited.
The compositions of preventing/treating sheep urinary calculus provided by the invention can play clearing away heat and promoting diuresis, improve the effect of urine pH, according to the mass fraction, comprises following component:
Receptaculum Helianthi 20 ~ 40 parts, Caulis Cucurbitae 10 ~ 30 parts, Herba Plantaginis 10 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 1 ~ 10 part, Herba Lysimachiae 1 ~ 15 part, ammonium salt 5 ~ 10 parts, bicarbonate 10 ~ 30 parts, magnesium oxide 5 ~ 10 parts.
Concrete, described ammonium salt is ammonium chloride, and bicarbonate is sodium bicarbonate;
Find that all there is good prophylactic treatment effect in following ranges through repetition test, according to the mass fraction, comprise following component:
Receptaculum Helianthi 20.0 ~ 30.0 parts, Caulis Cucurbitae 10.0 ~ 20.0 parts, Herba Plantaginis 10.0 ~ 20.0 parts of, Rhizoma Dioscoreae Septemlobae 5.0 ~ 8.0 parts, Herba Lysimachiae 5.0 ~ 10.0 parts, ammonium chloride 5.0% ~ 10.0 part, sodium bicarbonate 15.0 ~ 24.0 parts, magnesium oxide 5.0 ~ 8.0 parts forms in proportion.Wherein:
Receptaculum Helianthi: clearing away damp-heat, diuresis, by wind.
Caulis Cucurbitae: suppressing the hyperactive liver and easing the stomach, the meridian dredging, sharp blood vessels, kidney nourishing water.
Herba Plantaginis: clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.
Rhizoma Dioscoreae Septemlobae: expelling wind and removing dampness.
Herba Lysimachiae: clearing away heat and promoting diuresis, wind-expelling pain-stopping, hemostasia and promoting granulation.
Sodium bicarbonate/ammonium chloride: there is collaborative diuresis, can strongly and rapidly in and gastric acid, blood plasma intracellular bicarbonate salinity can be made to raise, blood pH value rises, free carbonic acid hydrion can be impelled to discharge with urine, urine pH is raised in alkalescence, urate calculus is dissolved.
Magnesium oxide: have antiacid laxative effective, suppresses and alleviates hyperchlorhydria, in and gastric acid effect by force and slowly lasting, with sodium bicarbonate, there is strong synergism.
The preparation method of the compositions of described preventing/treating sheep urinary calculus is: will pulverize after said medicine mixing or pulverize rear mixing, gained powder be the compositions of preventing/treating sheep urinary calculus, and the ratio according to 1.0 ~ 3.0% is mixed in daily feedstuff and feeds.
Further, in mass fraction, provide several preferred formula combination below:
Receptaculum Helianthi 40.0 parts, Caulis Cucurbitae 30.0 parts, Herba Plantaginis 30.0 parts of, Rhizoma Dioscoreae Septemlobae 10.0 parts, Herba Lysimachiae 15.0 parts, ammonium chloride 10.0 parts, sodium bicarbonate 30.0 parts, magnesium oxide 10.0 parts.
Receptaculum Helianthi 27.0 parts, Caulis Cucurbitae 18.0 parts, Herba Plantaginis 12.0 parts of, Rhizoma Dioscoreae Septemlobae 8.0 parts, Herba Lysimachiae 7.0 parts, ammonium chloride 8.0 parts, sodium bicarbonate 14.0 parts, magnesium oxide 6.0 parts.
Receptaculum Helianthi 25.0 parts, Caulis Cucurbitae 20.0 parts, Herba Plantaginis 15.0 parts of, Rhizoma Dioscoreae Septemlobae 5.0 parts, Herba Lysimachiae 5.0 parts, ammonium chloride 7.0 parts, sodium bicarbonate 15.0 parts, magnesium oxide 8.0 parts.
Receptaculum Helianthi 22.0 parts, Caulis Cucurbitae 18.0 parts, Herba Plantaginis 17.0 parts of, Rhizoma Dioscoreae Septemlobae 6.0 parts, Herba Lysimachiae 9.0 parts, ammonium chloride 9.0 parts, sodium bicarbonate 13.0 parts, magnesium oxide 6.0 parts.
Receptaculum Helianthi 30.0 parts, Caulis Cucurbitae 20.0 parts, Herba Plantaginis 10.0 parts of, Rhizoma Dioscoreae Septemlobae 8.0 parts, Herba Lysimachiae 10.0 parts, ammonium chloride 8.0 parts, sodium bicarbonate 24.0 parts, magnesium oxide 5.0 parts.
Receptaculum Helianthi 35.0 parts, Caulis Cucurbitae 25.0 parts, Herba Plantaginis 20.0 parts of, Rhizoma Dioscoreae Septemlobae 10.0 parts, Herba Lysimachiae 5.0 parts, ammonium chloride 5.0 parts, sodium bicarbonate 15.0 parts, magnesium oxide 5.0 parts.
Provide the result of use of the compositions of preventing/treating sheep urinary calculus below:
Test one: select public lamb sheep (the Suffolk ♂ × Small-fat-tail sheep ♀) 200 of a Sa Han generation for 3 monthly ages wean, be divided into test group (100) and matched group (100), test group according to 1.0 ~ 2.0% ratio by the pharmaceutical composition (Receptaculum Helianthi 25.0% of above-mentioned preventing/treating sheep urinary calculus, Caulis Cucurbitae 20.0%, Herba Plantaginis 15.0%, Rhizoma Dioscoreae Septemlobae 5.0%, Herba Lysimachiae 5.0%, ammonium chloride 7.0%, sodium bicarbonate 15.0%, magnesium oxide 8.0%) be mixed in daily feedstuff and feed, matched group is only fed daily feedstuff, carry out the Experiment On Fattening of 3 months by a definite date.Result shows: feed intake and the average daily gain of test group are better than matched group, significant difference (P < 0.05), through observe and detection experiment group without uriasis, uriasis sickness rate is 0, matched group finds 27 routine uriasis sheep, and uriasis sickness rate is 13.5% (see table 1).
Table 1 prevents the result of use of the compositions of sheep urinary calculus
Test two: select public lamb sheep (the Suffolk ♂ × Small-fat-tail sheep ♀) 20 of a Sa Han generation for 5 monthly ages wean, all suffers from urinary calculus, utilize clinical examination in conjunction with B ultrasonic detection technique, according to the difference of extent, matching method is used to be divided into test group and matched group, test group according to 2.0 ~ 3.0% ratio by the pharmaceutical composition (Receptaculum Helianthi 25.0% of above-mentioned preventing/treating sheep urinary calculus, Caulis Cucurbitae 20.0%, Herba Plantaginis 15.0%, Rhizoma Dioscoreae Septemlobae 5.0%, Herba Lysimachiae 5.0%, ammonium chloride 7.0%, sodium bicarbonate 15.0%, magnesium oxide 8.0%) be mixed in daily feedstuff and feed, matched group is only fed daily feedstuff, feed 3 months, observe and detect sick sheep treatment situation.Result shows, test group uriasis cure rate reaches 40%, effective percentage reaches 50%, mortality rate is only 10%, and the uriasis cure rate of matched group is only 10%, effective percentage is 10%, mortality rate up to 80%, significant difference (P < 0.05) (see table 2).
The result of use of sheep urinary calculus compositions treated by table 2
With Chinese herbal medicine additive of the present invention according to 1.0% ~ 2.0% ratio be mixed in the daily feedstuff of meat sheep, feed 3 months, other conditions are constant.Be 0 through observing and detecting uriasis sickness rate.
With Chinese herbal medicine additive of the present invention according to 2.0% ~ 3.0% ratio be mixed in the daily feedstuff of meat sheep, feeding 3 months, occurring through observing flock of sheep without epidemic disease, without uriasis, before feeding, just the ram of trouble uriasis is eased and fully recovers.
The compositions of preventing/treating sheep urinary calculus provided by the invention, has the effect of clearing away heat and promoting diuresis, expelling wind and removing dampness, removing pathogenic heat from blood and toxic substance from the body, and can improve urine pH, urate calculus is dissolved.Said composition can be taken directly to sheep as additive, feeds by daily raising the generation reaching prevention and therapy feeding sheep urinary stone.Especially be applicable to drylot feeding use as additive with in sheep feedstuff, described sheep is meat type, hair meat dual-purpose type or meat hair dual-purpose type; Or make medicine to take to sheep, with powder as well; Make additive or medicine and all have that preparation is simple, the advantage of low in raw material price.

Claims (10)

1. a compositions for preventing/treating sheep urinary calculus, is characterized in that, according to the mass fraction, comprises following component:
Receptaculum Helianthi 20 ~ 40 parts, Caulis Cucurbitae 10 ~ 30 parts, Herba Plantaginis 10 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 1 ~ 10 part, Herba Lysimachiae 1 ~ 15 part, ammonium salt 5 ~ 10 parts, bicarbonate 10 ~ 30 parts, magnesium oxide 5 ~ 10 parts.
2. the compositions of preventing/treating sheep urinary calculus as claimed in claim 1, is characterized in that, according to the mass fraction, comprise following component:
Receptaculum Helianthi 20 ~ 30 parts, Caulis Cucurbitae 10 ~ 20 parts, Herba Plantaginis 10 ~ 20 parts of, Rhizoma Dioscoreae Septemlobae 5 ~ 8 parts, Herba Lysimachiae 5 ~ 10 parts, ammonium salt 5 ~ 10 parts, bicarbonate 15 ~ 24 parts, magnesium oxide 5 ~ 8 parts.
3. the compositions of preventing/treating sheep urinary calculus as claimed in claim 1, is characterized in that, according to the mass fraction, comprise following component:
Receptaculum Helianthi 30 ~ 40 parts, Caulis Cucurbitae 20 ~ 30 parts, Herba Plantaginis 20 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 8 ~ 10 parts, Herba Lysimachiae 8 ~ 10 parts, ammonium salt 5 ~ 10 parts, bicarbonate 15 ~ 25 parts, magnesium oxide 5 ~ 8 parts.
4. the compositions of preventing/treating sheep urinary calculus as claimed in claim 1, is characterized in that, according to the mass fraction, comprise following component:
Receptaculum Helianthi 20 ~ 25 parts, Caulis Cucurbitae 15 ~ 20 parts, Herba Plantaginis 10 ~ 15 parts of, Rhizoma Dioscoreae Septemlobae 5 ~ 10 parts, Herba Lysimachiae 5 ~ 10 parts, ammonium salt 5 ~ 8 parts, bicarbonate 20 ~ 24 parts, magnesium oxide 5 ~ 8 parts.
5. the compositions of preventing/treating sheep urinary calculus as claimed in claim 1, is characterized in that, according to the mass fraction, comprise following component:
Receptaculum Helianthi 25 parts, Caulis Cucurbitae 20 parts, Herba Plantaginis 15 parts of, Rhizoma Dioscoreae Septemlobae 5 parts, Herba Lysimachiae 5 parts, ammonium salt 7 parts, bicarbonate 15 parts, magnesium oxide 8 parts.
6., as the compositions of the preventing/treating sheep urinary calculus of Claims 1 to 5 as described in any one, it is characterized in that, described ammonium salt is ammonium chloride, and bicarbonate is sodium bicarbonate.
7. a preparation method for the compositions of preventing/treating sheep urinary calculus, is characterized in that, comprises following operation:
Each component is taken: Receptaculum Helianthi 20 ~ 40 parts, Caulis Cucurbitae 10 ~ 30 parts, Herba Plantaginis 10 ~ 30 parts of, Rhizoma Dioscoreae Septemlobae 1 ~ 10 part, Herba Lysimachiae 1 ~ 15 part, ammonium salt 5 ~ 10 parts, bicarbonate 10 ~ 30 parts, magnesium oxide 5 ~ 10 parts by following mass parts;
To pulverize after each component mixing or pulverize rear mixing, gained powder be the compositions of preventing/treating sheep urinary calculus.
8. the preparation method of the compositions of preventing/treating sheep urinary calculus as claimed in claim 7, it is characterized in that, described ammonium salt is ammonium chloride, and bicarbonate is sodium bicarbonate;
Also by gained powder according to 1.0 ~ 3.0% mass ratio be mixed in sheep hurdle feedstuff.
9. the application of compositions in the medicine preparing preventing/treating sheep urinary calculus or feed additive of the preventing/treating sheep urinary calculus of Claims 1 to 5 described in any one.
10. applying as claimed in claim 9, it is characterized in that, is that described sheep is meat type, hair meat dual-purpose type or meat hair dual-purpose type in the application of preparation drylot feeding in sheep feedstuff.
CN201410649161.3A 2014-11-14 2014-11-14 A kind of composition of preventing/treating sheep urolithiasis and its preparation method and application Expired - Fee Related CN104352716B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
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CN104799096A (en) * 2015-04-29 2015-07-29 宁夏大北农科技实业有限公司 Fattening concentrated feed for preventing mutton sheep urinary stone and preparation method of fattening concentrated feed
CN104799002A (en) * 2015-05-18 2015-07-29 山东新希望六和集团有限公司 Feed additive for treating goat urolithiasis and preparation method thereof
CN105125610A (en) * 2015-09-16 2015-12-09 吉林大学 Application of sunflower disc hydrolysis compound powder in preparing of medicine for curing or relieving high uric acid gout
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CN105125610B (en) * 2015-09-16 2018-10-02 吉林大学 Sunflower disk hydrolyzes application of the compound powder in preparing treatment or alleviating high lithemia gout disease drug
CN106212902A (en) * 2016-06-21 2016-12-14 湖北省农业科学院畜牧兽医研究所 A kind of Boehmeria type full hybrid particles feedstuff preventing meat sheep urolithiasis and preparation method

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