CN103272085B - Traditional Chinese medicine composition for treating eperythrozoonosis of dairy cows and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating eperythrozoonosis of dairy cows and preparation method thereof Download PDFInfo
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- CN103272085B CN103272085B CN201310200485.4A CN201310200485A CN103272085B CN 103272085 B CN103272085 B CN 103272085B CN 201310200485 A CN201310200485 A CN 201310200485A CN 103272085 B CN103272085 B CN 103272085B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating eperythrozoonosis of dairy cows and a preparation method thereof, and relates to a medicine for treating eperythrozoonosis of dairy cows. The traditional Chinese medicine composition is formed by mixing antifebrile dichroa, areca-nut, isatis root, fructus forsythiae, radix scrophulariae, Codonopsis pilosula, Angelica sinensis, Rhizoma Atractylodis Macrocephalae, liquorice and Artemisia apiacea. The preparation method comprises the following steps of: mixing the raw materials; adding water to soak and decoct for a certain time; and filtering. The composition is safe, effective and free from resistance to medicine, and has the functions of killing worms and removing qi stagnation, clearing away heat and toxic materials, stopping bleeding and cooling blood, tonifying qi and blood, harmonizing stomach and tonifying spleen, and enhancing the resistance and immunity of a human body.
Description
Technical field
The invention belongs to Chinese veterinary medicinal composition, particularly be that one treats eperythrozoonosis in dairy cow composition and method of making the same.
Background technology
Eperythrozoonosis in dairy cow parasitizes ORBC surface, blood plasma and bone marrow by Eperythrozoon, a kind of zoonosis being Clinical symptoms with anemia, hemolytic jaundice, heating, dyspnea.China is one of popular country the most serious of eperythrozoonosis in dairy cow, and existing 20 provinces, cities and autonomous regions report the generation of this disease at present.Along with developing rapidly of milk cow production, intensive degree is more and more higher, and this disease changes four seasons morbidity into by Seasonal Incidence, and indivedual regional E.wenyoni infection rate is up to 50%-90%.This disease can cause that milch cow grows slowly, milk yield declines and breeding difficulty, and the production diseases such as normal and endometritis, mastitis and parturient paresis are concurrent, bring huge economic loss to milk cow production.Simultaneously, eperythrozoonosis in dairy cow the health of the mankind as a kind of zoonosis serious threat, and some regional people's infection rate, up to 40%, even can reach more than 70% in teenager, showing as chronic fatigue syndrome, also there is abnormality of nerve function and sleep disorder in some patients.Owing to showing sub-health state after most of patients infection, this disease is cured clinical often out in the cold people.
The specific drug of current treatment eperythrozoonosis in dairy cow is little, and main antiparasitic Western medicine imidazophenylurea, Diminazene Aceturate (Benny's that) and oxytetracycline, doxycycline, the penicillin etc. of adopting carry out deinsectization anti-inflammation clinically, but effect is all undesirable.Imidazophenylurea treats this disease comparatively effectively, but this medicine can not enter bone marrow, thoroughly can not kill Eperythrozoon, and expensive, and drug withdrawal is easily recurred.Diminazene Aceturate has larger toxic and side effects, and safety range is little, easily produces drug residue.
Summary of the invention
It is imprecise that application antibiotics treats this sick effect, and polypide easily produces drug resistance, and thoroughly can not remove pathogen, easily causes drug residue.Arsenic preparation metrifonate liquid can treat Eperythrozoon wenyonii disease, but easily causes the residual of poisonous arsenic in beef and milk.
The Traditional Chinese medicinal prescription of conventional malaria and anthelmintic treats this disease clinically, the prescription as people's research and development such as Guo Hongjun: Herba Artemisiae Annuae, Radix Dichroae, Herba Ephedrae, Semen Armeniacae Amarum, Gypsum Fibrosum, Semen Lepidii (Semen Descurainiae), Cortex Lycii, Cortex Mori, the Rhizoma Anemarrhenae, Radix Scutellariae, Radix Glycyrrhizae; The and for example suitable prescription waiting people of ten thousand states: Herba Artemisiae Annuae, Cornu Bubali, Radix Scrophulariae, Fructus Gardeniae, Radix Platycodonis, Radix Scutellariae, the Rhizoma Anemarrhenae, the Radix Paeoniae Alba, Fructus Forsythiae, the Radix Rehmanniae, fresh Folium Bambusae, Cortex Moutan, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Herba Agrimoniae, Herba Ecliptae, Radix Glycyrrhizae.This kind of prescription comprises the Radix Scrophulariae, Gypsum Fibrosum etc. that have and rush down lower function, can rush down lower interior-heat, have certain curative effect while expeling polypide, but fails to alleviate anemia and jaundice symptom, and the more weak sick cattle of body constitution there will be insufficiency of the spleen loose stool, increases the weight of the state of an illness.Also see this disease of therapy of combining Chinese and Western medicine clinically, the Traditional Chinese medicinal prescription of common collocation Western medicine has decoction of ten powerful tonics, Radix Codonopsis supports flourish soup etc.SHIQUAN DABU FANG combined with westem can obviously alleviate cause because infecting Eperythrozoon anemia, jaundice and anaphylaxis, but thoroughly can not remove polypide, easily repeatedly.Flourish soup energy mitigate the disease supported by Radix Codonopsis, improves and suffers from poultry appetite, but can not remove polypide, easily recur, cure the symptoms, not the disease.Therefore the Chinese medicine composition developing safe and efficient treatment eperythrozoonosis in dairy cow develops in a healthy way significant to milk cow production.
Summary of the invention
The object of the invention is for treating eperythrozoonosis in dairy cow Problems existing at present, research and develop a kind of Chinese medicine composition for the treatment of eperythrozoonosis in dairy cow and preparation method thereof, reach and improve eperythrozoonosis in dairy cow cure rate, not easily recur, and object that is with low cost, that have no side effect.
The object of the present invention is achieved like this: said composition is prepared by following raw material and consumption: Radix Dichroae 45-60g, Semen Arecae 45-60g, Radix Isatidis 45-60g, Fructus Forsythiae 30-50g, Radix Scrophulariae 20-40g, Radix Codonopsis 40-60g, Radix Angelicae Sinensis 40-60g, Rhizoma Atractylodis Macrocephalae 40-60g, Radix Glycyrrhizae 30-50g, Herba Artemisiae Annuae 20-45g.Add normal-temperature water 2000-2500ml in Radix Dichroaes whole in dosage, Semen Arecae, Radix Isatidis, Fructus Forsythiae, Radix Scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, soak 60 minutes, 30-45 minute at a simmer, filter and remove residue obtains medicinal liquid and is about 50mL; 1500-2000mL water is added again in the medicinal residues after filtration, 30-45 minute at a simmer, filter medicinal liquid is about 50mL, merge the medicinal liquid that twice is filtered gained, after the medicinal liquid of merging is down to 50-60 DEG C, the Herba Artemisiae Annuae that heat-insulation soaking 20-45g batters down 2 hours, crosses elimination medicinal residues, finally obtains the Chinese medicine composition of potion treatment eperythrozoonosis in dairy cow.
This Chinese medicine composition draw materials extensive, with low cost, safe and effective, without Drug resistance, easy to use, not repeatedly, there is effect of killing insect and eliminating accumulation, heat-clearing and toxic substances removing, hemostasis removing heat from blood, rich in nutrition, stomach function regulating spleen invigorating, enhancing body resistance and immunity.In several years, adopt said composition to treat the milch cow that 153 are suffered from eperythrozoonosis in dairy cow, cure 140, dead 3, cure rate reaches more than 90%, and after curing not repeatedly, evident in efficacy.This Chinese medicine composition is significant for the sound development for the treatment of eperythrozoonosis in dairy cow, promotion milk cow production.
Detailed description of the invention
Give an actual example below and describe the present invention.
Get Radix Dichroae 50g, Semen Arecae 50g, Radix Isatidis 45g, Fructus Forsythiae 30g, Radix Scrophulariae 30g, Radix Codonopsis 45g, Radix Angelicae Sinensis 45g, Rhizoma Atractylodis Macrocephalae 45g, Radix Glycyrrhizae 35g, Herba Artemisiae Annuae 30g respectively.
Process for preparation is as follows: add normal-temperature water 2000mL in Radix Dichroaes whole in dosage, Semen Arecae, Radix Isatidis, Fructus Forsythiae, Radix Scrophulariae, Radix Codonopsis, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, and soak 60 minutes, 40 minutes at a simmer, filter and remove residue obtained medicinal liquid and is about 50mL; 2000mL water is added again in the medicinal residues after filtration, 40 minutes at a simmer, filter medicinal liquid is about 50mL, merge the medicinal liquid of twice, after the medicinal liquid of merging is down to 50-60 DEG C, the Herba Artemisiae Annuae that heat-insulation soaking 45g batters down 2 hours, crosses elimination medicinal residues, obtains the Chinese medicine composition of potion treatment eperythrozoonosis in dairy cow.
Using method is as follows: gavage the compositions of the above-mentioned treatment eperythrozoonosis in dairy cow Chinese medicine be mixed with to ill milch cow, and sooner or later respectively once, every day 1 dose, drinks the state of an illness and is used in conjunction 4-7 agent.
Treat disease row 1
Cowboying family, Shangzhi City, Heilongjiang Province on the 6th August in 2012 man 4 years old breast milk cattle is ill; main suit: this milch cow ill fever before a week; in township, veterinary station is diagnosed as eperythrozoonosis; be down to normally through Western medicine imidazophenylurea treatment body temperature, but lacking of eating, ruminate few; out of spirits; Sleep hyperhidrosis, once used the treatments such as cephalosporin, dense glucose, aminoacid, caffeine and sodium benzoate, DeGrain.Examine it, suffer from poultry fatigue and lack of strength, be reluctant to walk, eye conjunctiva is yellowish, diarrhea, yellowish urine, palpitation and being susceptible to fright, is diagnosed as the Eperythrozoon positive through this city animal epidemic monitoring center.Use above-mentioned traditional Chinese medicine composition for treating, every day 1 dose, serve on 6 doses, main state medication after the 3rd day symptom alleviate, recovery from illness in the 6th day.Call-on back by phone after half a year, does not recur again.
Treat disease row 2
On May 28th, 2012, revive the cow head that certain is raised in Liuhe town, Mulan County, Heilongjiang Province, body weight 600 kg, daily output fresh milk 30 kg, 90 days puerperal, unexpected poor appetite, was slow in action, and spirit is depressed, and milk yield declines, and cough is suffered from diarrhoea.Clinical examination: it is thin to suffer from cattle, visual mucosa and breast xanthochromia, and rumen peristalsis weakens, and by promptly holding a consultation and lab testing, determines that Eperythrozoon is positive, and you turn slightly getting better after trouble Niu Jinhang treatment to adopt Benny, but after stopping treatment first quarter moon, the state of an illness is again repeatedly.Sick cattle uses above-mentioned traditional Chinese medicine composition for treating immediately, every day 1 dose, serve on 5 doses, main state medication after second day symptom namely alleviate, suffer from cattle and recover diet wish gradually, within the 5th day, recover, further consultation after first quarter moon, suffer from drink heavily appetite normal, milk yield increases, and have sharp ears microscopic examination of perpheral blood smear Eperythrozoon is turned out cloudy.
Treat disease row 3
In mid-July, 2012, have 9 Adult Bovine appetite to decline in the cow head of cattle farm, Baicheng City in Jilin Province 23, ruminate minimizing, body temperature is increased to 40-41.5 DEG C, breathes fast, and milk yield declines; There is hematuria in minority cattle, constipation alternately occurs there are 3 sick beefsteak hemafecias with diarrhoea, wherein 1 Pregnant cows miscarriage; 2 calves are had to occur jaundice.According to clinical symptoms and microscopic examination of perpheral blood smear result, it is eperythrozoonosis that cattle is suffered from diagnosis, and you treat in conjunction with oxytetracycline to take Benny, do not become effective.Use above-mentioned traditional Chinese medicine composition for treating immediately, every day 1 dose, serve on 7 doses, after master states most sick cattle medication, the 3rd day symptom obviously alleviates, and within the 7th day, recovers normal afterwards.There is the adult dairy cattle skeletonize that is seriously ill, dead in second day for the treatment of.After death cut open inspection to find, cattle corpse skeletonize of dying of illness, skin elasticity reduces, and cadaveric rigidity is obvious; Visual mucosa is pale, xanthochromia; Lymph nodes of body as a whole enlargement, cortex is aubergine or taupe, and tangent plane turns up succulence; Blood coagulation is bad, in cerise; Cardiac muscle expansion, pale soft, visceral pericardium, the heart are preced with fatty xanthochromia and are dispersed in the remote hemorrhage point that differs in size; Liver enlargement, in brown color; Gollbladder dilation, bile is dense thick; Kidney edema, has a small amount of petechia; Cut open other tissue of inspection and have no obvious pathological changes.Altogether for 9 routine sick milch cows are treated by this plant, cure 8 examples, dead 1 example.
Treat disease row 4
In November, 2012, the author has accepted the milch cow that 1 is suffered from eperythrozoonosis for medical treatment.Disease cattle body temperature 39.8 DEG C, by hair slightly disorderly, spirit is depressed, and appetite reduces or gives up with ruminating absolutely; Visual mucosa xanthochromia, with mastitis; Constipation, feces is stiff is covered with mucus.Through the treatment of this Chinese medicine composition material, sick cattle was clearly better after 3 days, and within 7 days, recover normal afterwards, drug withdrawal is after one week, and detect through blood smear Acridine orange microscopy and elisa respectively, result transfers feminine gender to.
Claims (1)
1. treat a Chinese medicine composition for eperythrozoonosis in dairy cow, it is characterized in that said composition is prepared by following raw material, dose and method: Radix Dichroae 45-60g, Semen Arecae 45-60g, Radix Isatidis 45-60g, Fructus Forsythiae 30-50g, Radix Scrophulariae 20-40g, Radix Codonopsis 40-60g, Radix Angelicae Sinensis 40-60g, Rhizoma Atractylodis Macrocephalae 40-60g, Radix Glycyrrhizae 30-50g; In the raw material of above-mentioned all categories and quality, add normal-temperature water 2000-2500mL, soak 45 minutes, 30-45 minute at a simmer, filter and remove residue obtains medicinal liquid and is about 50mL; 1500-2000mL water is added again in the medicinal residues after filtration, 30-45 minute at a simmer, filter medicinal liquid is about 50mL, merge the medicinal liquid of twice, after the medicinal liquid of merging is cooled to 50-60 DEG C, the Herba Artemisiae Annuae 25-45g that heat-insulation soaking batters down 2 hours, filter and remove residue, finally obtains the Chinese medicine composition of potion treatment eperythrozoonosis in dairy cow.
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| CN103960542B (en) * | 2014-05-20 | 2016-04-20 | 山东新希望六和集团有限公司 | A kind of feed for preventing and treating swine eperythrozoonosis and Chinese medicine composition |
| CN104288273B (en) * | 2014-10-13 | 2017-06-06 | 天津瑞贝特科技发展有限公司 | Treat Chinese and western medicinal composition of eperythrozoonosis in dairy cow and preparation method thereof |
| CN105769988A (en) * | 2014-12-26 | 2016-07-20 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine composition for treating swine eperythrozoonosis and preparation method thereof |
| CN105596634A (en) * | 2016-01-22 | 2016-05-25 | 冯悠慈 | Traditional Chinese medicine composition for treating swine eperythrozoonosis and preparation method and application thereof |
| CN109498727A (en) * | 2018-12-28 | 2019-03-22 | 舞钢市畜产品质量检测中心 | A kind of Chinese medicine composition and preparation method thereof for treating eperythrozoonosis |
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| CN101879201A (en) * | 2010-07-02 | 2010-11-10 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for preventing and curing eperythrozoonosis of pigs, sheep and cows and preparation method thereof |
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| CN101879201A (en) * | 2010-07-02 | 2010-11-10 | 中国农业科学院兰州畜牧与兽药研究所 | Medicine for preventing and curing eperythrozoonosis of pigs, sheep and cows and preparation method thereof |
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