CN105381300A - Traditional Chinese medicinal preparation for preventing and treating swine fever - Google Patents

Traditional Chinese medicinal preparation for preventing and treating swine fever Download PDF

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CN105381300A
CN105381300A CN201510921916.5A CN201510921916A CN105381300A CN 105381300 A CN105381300 A CN 105381300A CN 201510921916 A CN201510921916 A CN 201510921916A CN 105381300 A CN105381300 A CN 105381300A
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杨君丽
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract

The invention belongs to the technical field of veterinary traditional Chinese medicines, and provides a traditional Chinese medicinal preparation for preventing and treating swine fever to solve the problems of unsatisfactory effects and large side effects of present medicines for treating the swing fever. The traditional Chinese medicinal preparation is prepared from cassia seed, isatis root, Weeping Forsythia, Rhizoma Anemarrhenae, Ligusticum wallichii, reed rhizome, mung bean, unprocessed rehmannia root, Rhizoma Cimicifugae, Achyranthes bidentata and Cornu Bubali according to certain proportions. The traditional Chinese medicinal preparation has the advantages of substantial effects, no toxic or side effects, no obvious negative effects on pigs' ingestion, positive effects on the feed/gain ratio, small dosage, low cost, high curative effects, and facilitation of increase of the income of swine feeders. 1000 Cases of swine fever are definitely diagnosed through blood inspection by using a modern medical science apparatus. 960 Cases are cured by the preparation, 20 cases are improved by the preparation, and the preparation is ineffective to 20 cases, so the effective rate is 98%, and the cure rate is 96%.

Description

A kind of Chinese medicine preparation of Prevention and Curation hog cholera
Technical field
The invention belongs to field of traditional Chinese medicine technology for animals, be specifically related to a kind of Chinese medicine preparation of Prevention and Curation hog cholera.
Background technology
Swine fever (Classicalswinefever, CSF) be a kind of high degree in contact sexually transmitted disease caused by swine fever virus (CSFV), be commonly called as " rinderpest ", it is a kind of Acute exposure sexually transmitted disease of pig, also known as hog cholera, its Clinical symptoms, for morbidity is anxious, high heat is delaied and minute blood vessel degeneration, causes the hemorrhage and splenic marginal infarction of whole body general property point etc.; It is characterized in that, acute, change in septic, organa parenchymatosum is hemorrhage, downright bad and infarction; Chronic in cellulosic necrotic enteritis, often there are paratyphoid fever and Bacillus pasteurii disease secondary in the later stage; This disease is an infected pigs under field conditions (factors), and the pig of all ages and classes, sex, kind and wild boar all susceptibles, all can occur throughout the year.Sick pig is major source of infection, sick pig excrements and secretions, sick dead pig and internal organs and corpse, anxious kill sick pig blood, meat, internal organs, waste water, waste entrainment feedstuff, drinking-water all can disseminate virus, the propagation of swine fever mainly through contact, through digestive tract infection.In addition, the sow that ill and low virulent strain infects also through Placenta Hominis vertical infection fetus, can produce weak piglet, stillborn fetus, mummy tire etc.
Current swine fever is popular usually to be showed irregular provincialism and distributes, and pathogeneticing characteristic is not true to type, to generate heat, depressed, the loss of appetite of spirit, cough, ataxia, conjunctivitis and diarrhoea, perinatal death, stillborn fetus, miscarriage.Mesogenic and strong poison infect and have these symptoms above, and in swinery fast propagation of all ages.
Current; swine fever is still during one of world's pig industry threatens .1997-1999 greatly and had all once repeatedly broken out swine fever in states such as Germany, Holland, Spain and Italy; the phenomenon declined at persistent infection and the vaccine Vaccine effectiveness of Chinese CSFV is also commonplace; this not only causes serious economic loss to pig industry, and brings certain difficulty to swine fever control policy making.Also have the chemoprophylaxis treatment hog cholera wanting to close in prior art, but effect is all undesirable, and side effect is large.
Summary of the invention
The present invention, in order to solve the problem that effect of drugs is undesirable, side effect is large of existing treatment hog cholera, provides a kind of Chinese medicine preparation of prophylactic treatment hog cholera.
The present invention is realized by following technical scheme: a kind of Chinese medicine preparation of Prevention and Curation hog cholera, be made up of the raw material of following weight portion: Semen Cassiae 6 ~ 8 parts, Radix Isatidis 10 ~ 20 parts, Fructus Forsythiae 5 ~ 10 parts, the Rhizoma Anemarrhenae 10 ~ 20 parts, Rhizoma Chuanxiong 5 ~ 10 parts, Rhizoma Phragmitis 5-10 part, Semen phaseoli radiati 15-20 part, Radix Rehmanniae 10-20 part, Rhizoma Cimicifugae 5-12 part, Radix Achyranthis Bidentatae 4-10 part, Cornu Bubali 20-30 part.
Optimum ratio is: be made up of the raw material of following weight portion: Semen Cassiae 7 parts, Radix Isatidis 15 parts, Fructus Forsythiae 8 parts, the Rhizoma Anemarrhenae 15 parts, Rhizoma Chuanxiong 7 parts, Rhizoma Phragmitis 9 parts, 18 parts, Semen phaseoli radiati, 15 parts, the Radix Rehmanniae, Rhizoma Cimicifugae 10 parts, Radix Achyranthis Bidentatae 8 parts, Cornu Bubali 26 parts.
The Chinese medicine preparation of described Prevention and Curation hog cholera is powder, is ground into 80-100 order, adds in feedstuff, free choice feeding to feed amount the day of 2%-5%.
The Chinese medicine preparation of described Prevention and Curation hog cholera is water decoction, filters, add 100ml filtrate, freely drink in every 1000ml water after each raw material mixing after conventional decocting.
In medicine of the present invention: Semen Cassiae is sweet, bitter, salty, is slightly cold.Return liver, large intestine channel.Clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Radix Isatidis is bitter, cold.GUIXIN, stomach warp.Heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.Fructus Forsythiae nature and flavor are bitter, are slightly cold.Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.Rhizoma Anemarrhenae nature and flavor are bitter, sweet, cold.Return lung, stomach, kidney channel.Clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.Rhizoma Chuanxiong nature and flavor are pungent, temperature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Rhizoma Phragmitis clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Semen phaseoli radiati nature and flavor are sweet, cold.Enter the heart, stomach warp.Heat-clearing and toxic substances removing, relieves summer heat.For summer-heat excessive thirst, the diseases such as sore carbuncle.Radix Aconiti Lateralis Preparata, Fructus Crotonis poison can be separated.Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.Rhizoma Cimicifugae nature and flavor are pungent, micro-sweet, are slightly cold.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle; Proctoptosis, uterine prolapse.Radix Achyranthis Bidentatae invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.Cornu Bubali heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.For the high heat of epidemic febrile disease, unconsciousness and delirium, sends out speckle dermexanthesis, hematemesis and epistaxis, infantile convulsion, demented.
Traditional Chinese veterinary medicine thinks that primary disease is caused by the evil poison of diseases caused by exogenous pathogenic factor epidemic disease; The body of diseases caused by exogenous pathogenic factor epidemic disease evil poison invasion and attack pig, straight criminal's gas battalion, then high heat, argol, lassitude, few food; Heresy invades battalion point, then intenseness of heat is joined the army, excessive noxious heat, consumption of body fluid by heat, then thirsty, happiness drink, and asoscope is dry, and diarrhoea, draws the loose stool of foul odour, and have keratitis; Excessive noxious heat, enters people's blood system, injures blood system, the absurd row of forcing blood, then under femoribus internus, abdomen, then form petechia in eyelid, lip, nose, the basal part of the ear, extremity.
Drug action mechanism of the present invention is: Semen Cassiae is the seed that leguminous plant stewes leaf Semen Cassiae or Semen Cassiae, include anthracene ester and anthraquinone glycoside, obtusin and vitamin A etc., pharmacological testing proves: Semen Cassiae has reducing blood pressure and reduces the effect of serum cholesterol, the effect under having anti-various pathogens and soft stool to rush down; Radix Isatidis heat-clearing and toxic substances removing, clearing throat; Fructus Forsythiae is the fruit of Oleaceae plants Fructus Forsythiae, includes volatile oil, forsythol, flavonoid glycoside, alkaloid etc., and pharmacological testing shows: Fructus Forsythiae has broad-spectrum antibacterial action, and contained forsythol may be main antipathogenic composition; Fructus Forsythiae also has antiinflammatory, town is told, the use of diuresis and heart tonifying; Contained flavonoid glycoside can strengthen the density of blood capillary, hemorrhage thus to caused by capillary rupture, and subcutaneous hemorrhage etc. all have anastalsis; Herba Andrographis hemostasis removing heat from blood, removing toxic substances and promoting tissue regeneration, reducing swelling and alleviating pain; The Rhizoma Anemarrhenae is the rhizome of the liliaceous plant Rhizoma Anemarrhenae, containing multiple Saponin and Saponin it, in addition containing two kinds of flavones ingredients, Mengiferins etc., test proves: the Rhizoma Anemarrhenae has obvious refrigeration function, and Epidemic Hemorrhagic Fever, epidemic encephalitis type B, pulmonary tuberculosis hectic fever all have aobvious curative effect; Rhizoma Chuanxiong has obvious sedation.Inhibited to the activity of animal brain when Rhizoma Chuanxiong volatile oil is a small amount of, and to medulla oblongata respiratory center, vasomotor center and spinal reflex maincenter, there is excitation.Rhizoma Chuanxiong Aqueous extracts and alkaloid thereof can expand crown and blood vessel, increase coronary flow, improve myocardial ischemia situation.Rhizoma Chuanxiong has inhibitory action to large intestine, dysentery (Song Nei Shi), distortion, green pus, typhoid fever, Salmonella paratyphi and vibrio cholera etc.Rhizoma Chuanxiong water logging agent (1:3) also has inhibitory action to some pathogenic dermatophytes in vitro.Rhizoma Phragmitis clearing away heat and promoting production of body fluid; Relieve restlessness and prevent vomiting; Diuresis; Rash.Semen phaseoli radiati heat-clearing and toxic substances removing, Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.Rhizoma Cimicifugae antimicrobial antiphlogistic, antipyretic-antalgic; Radix Achyranthis Bidentatae anti-inflammatory and antalgic, Cornu Bubali heat clearing away; Removing toxic substances; Removing heat from blood; Arresting convulsion.
Each medicine cooperatively interacts and jointly reaches the effect of prevention and therapy swine fever, and the present invention treats swine fever 1000 example, all makes a definite diagnosis through blood with modern medicine inspect by instrument.Result cures 960 examples, and take a turn for the better 20 examples, invalid 20 examples, effective percentage 98%, cure rate 96%.
Be very effective of the present invention, without any side effects, search for food without obvious negative effect to pig, have active influence to feed-weight ratio, and consumption is few, cost is low, and curative effect is high, is conducive to the income increasing pig farmer.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation of Prevention and Curation hog cholera, is made up of the raw material of following weight: Semen Cassiae 6g, Radix Isatidis 10g, Fructus Forsythiae 5g, Rhizoma Anemarrhenae 10g, Rhizoma Chuanxiong 5g, Rhizoma Phragmitis 5g, Semen phaseoli radiati 15g, Radix Rehmanniae 10g, Rhizoma Cimicifugae g, Radix Achyranthis Bidentatae 4g, Cornu Bubali 20g.The Chinese medicine preparation of described Prevention and Curation hog cholera is powder, is ground into 80-100 order, adds in feedstuff, free choice feeding to feed amount the day of 2%-5%.
Embodiment 2: a kind of Chinese medicine preparation of Prevention and Curation hog cholera, is made up of the raw material of following weight: Semen Cassiae 7g, Radix Isatidis 15g, Fructus Forsythiae 8g, Rhizoma Anemarrhenae 15g, Rhizoma Chuanxiong 7g, Rhizoma Phragmitis 9g, Semen phaseoli radiati 18g, Radix Rehmanniae 15g, Rhizoma Cimicifugae 10g, Radix Achyranthis Bidentatae 8g, Cornu Bubali 26g.The Chinese medicine preparation of described Prevention and Curation hog cholera is water decoction, filters, add 100ml filtrate, freely drink in every 1000ml water after each raw material mixing after conventional decocting.
Embodiment 3: a kind of Chinese medicine preparation of Prevention and Curation hog cholera, is made up of the raw material of following weight: Semen Cassiae 8g, Radix Isatidis 20g, Fructus Forsythiae 10g, Rhizoma Anemarrhenae 20g, Rhizoma Chuanxiong 10g, Rhizoma Phragmitis 10g, Semen phaseoli radiati 20g, Radix Rehmanniae 20g, Rhizoma Cimicifugae 12g, Radix Achyranthis Bidentatae 10g, Cornu Bubali 30g.The Chinese medicine preparation of described Prevention and Curation hog cholera is powder, is ground into 80-100 order, adds in feedstuff, free choice feeding to feed amount the day of 2%-5%.
Compliance test result: select 20,000 pigs from certain pig farm, be equally divided into four groups, four groups of piglets are without obvious ecological difference.One group of piglet conveniently feed mode is fed, as a control group; In its excess-three group pig starter feed, addition adds the Chinese medicine prepared by the embodiment of the present invention according to the rules, as experimental group.Feed to delivering for sale, two groups of feed-weight ratio difference are not obvious, and without obvious significant difference, statistics hog cholera sickness rate, hog cholera mortality rate, see the following form.After drug treatment is carried out to 1000 sick pigs, statistics display: effective percentage is 98%, and cure rate is 96%.
Project Matched group Embodiment 1 Embodiment 2 Embodiment 3
Hog cholera sickness rate/% 40 3 2 2
Hog cholera mortality rate/% 15 0 0 0

Claims (4)

1. the Chinese medicine preparation of a Prevention and Curation hog cholera, it is characterized in that: be made up of the raw material of following weight portion: Semen Cassiae 6 ~ 8 parts, Radix Isatidis 10 ~ 20 parts, Fructus Forsythiae 5 ~ 10 parts, the Rhizoma Anemarrhenae 10 ~ 20 parts, Rhizoma Chuanxiong 5 ~ 10 parts, Rhizoma Phragmitis 5-10 part, Semen phaseoli radiati 15-20 part, Radix Rehmanniae 10-20 part, Rhizoma Cimicifugae 5-12 part, Radix Achyranthis Bidentatae 4-10 part, Cornu Bubali 20-30 part.
2. the Chinese medicine preparation of a kind of Prevention and Curation hog cholera according to claim 1, it is characterized in that: be made up of the raw material of following weight portion: Semen Cassiae 7 parts, Radix Isatidis 15 parts, Fructus Forsythiae 8 parts, the Rhizoma Anemarrhenae 15 parts, Rhizoma Chuanxiong 7 parts, Rhizoma Phragmitis 9 parts, 18 parts, Semen phaseoli radiati, 15 parts, the Radix Rehmanniae, Rhizoma Cimicifugae 10 parts, Radix Achyranthis Bidentatae 8 parts, Cornu Bubali 26 parts.
3. the Chinese medicine preparation of a kind of Prevention and Curation hog cholera according to claim 1 and 2, is characterized in that: the Chinese medicine preparation of described Prevention and Curation hog cholera is powder, is ground into 80-100 order, adds in feedstuff, free choice feeding to feed amount the day of 2%-5%.
4. the Chinese medicine preparation of a kind of Prevention and Curation hog cholera according to claim 1 and 2, it is characterized in that: the Chinese medicine preparation of described Prevention and Curation hog cholera is water decoction, filter after conventional decocting after each raw material mixing, add 100ml filtrate in every 1000ml water, freely drink.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620354A (en) * 2017-02-09 2017-05-10 安徽菲扬农业科技有限公司 Feed additive for preventing swine fever
CN108578592A (en) * 2018-06-13 2018-09-28 浙江大飞龙动物保健品股份有限公司 Prevent the preparation and preparation method thereof of hog cholera
CN109793816A (en) * 2019-03-29 2019-05-24 刘坚 The herbal composite and its processing method of a kind of prevention and control swine fever and application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491509A (en) * 2014-12-04 2015-04-08 郭志平 Traditional Chinese medicine preparation for treating classical swine fever

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491509A (en) * 2014-12-04 2015-04-08 郭志平 Traditional Chinese medicine preparation for treating classical swine fever

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620354A (en) * 2017-02-09 2017-05-10 安徽菲扬农业科技有限公司 Feed additive for preventing swine fever
CN108578592A (en) * 2018-06-13 2018-09-28 浙江大飞龙动物保健品股份有限公司 Prevent the preparation and preparation method thereof of hog cholera
CN109793816A (en) * 2019-03-29 2019-05-24 刘坚 The herbal composite and its processing method of a kind of prevention and control swine fever and application

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