CN104491358A - Traditional Chinese medicine preparation for treating early-stage swine fever - Google Patents

Traditional Chinese medicine preparation for treating early-stage swine fever Download PDF

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CN104491358A
CN104491358A CN201410726483.3A CN201410726483A CN104491358A CN 104491358 A CN104491358 A CN 104491358A CN 201410726483 A CN201410726483 A CN 201410726483A CN 104491358 A CN104491358 A CN 104491358A
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CN104491358B (en
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郭志平
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Shenzhen Huatai Biological Pharmaceutical Co.,Ltd.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
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Abstract

The invention belongs to the technical field of veterinary traditional Chinese medicine and traditional Chinese medicines and aims at solving the problems of non-ideal pharmaceutical effect and great side effects in existing treatment and prevention of swine fever and providing a traditional Chinese medicine preparation for treating early-stage swine fever. The traditional Chinese medicine preparation is prepared from roasted ephedra herb, apricot kernels, platycodon root, loquat leaves, thunberg fritillary bulb, whiteflower hogfennel root, roasted liquorice root, raw gypsum, baical skullcap root, heartleaf houttuynia herb, Indian buead, sessile stemona root, manchurian wildginger and raw liquorice root according to a certain proportion. The traditional Chinese medicine preparation is used for treating the early-stage fever with the symptoms of cough, high fever, shivering, open mouth breathing, rhinorrhea, dry dung, yellowish urine, loss of appetite, skin redness and bleeding points or bleeding spots at individual swine pores. The traditional Chinese medicine preparation has significant effect, has no toxicity or side effects, has no obvious adverse effects on intaking of pigs, has positive effects on feed-gain ratio and is further small in using amount, low in cost and conductive to increasing the profits of pig farmers.

Description

A kind of Chinese medicine preparation for the treatment of initial stage hog cholera
Technical field
The invention belongs to field of traditional Chinese medicine technology for animals, be specifically related to a kind of Chinese medicine preparation for the treatment of initial stage hog cholera.
Background technology
It is that one has hyperinfection epidemic disease that swine fever is commonly called as " rinderpest ", and be one of Infectious Diseases threatening pig industry, it is characterized in that: acute, change in septic, organa parenchymatosum is hemorrhage, downright bad and infarction; Chronic in cellulosic necrotic enteritis, often there are paratyphoid fever and Bacillus pasteurii disease secondary in the later stage.
This disease is an infected pigs under field conditions (factors), and the pig of all ages and classes, sex, kind and wild boar all susceptibles, all can occur throughout the year.Sick pig is major source of infection, sick pig excrements and secretions, sick dead pig and internal organs and corpse, anxious kill sick pig blood, meat, internal organs, waste water, waste entrainment feedstuff, drinking-water all can disseminate virus, the propagation of swine fever mainly through contact, through digestive tract infection.In addition, the sow that ill and low virulent strain infects also through Placenta Hominis vertical infection fetus, can produce weak piglet, stillborn fetus, mummy tire etc.
Current swine fever is popular usually to be showed irregular provincialism and distributes. pathogeneticing characteristic is not true to type, to generate heat, depressed, the loss of appetite of spirit, cough, ataxia, conjunctivitis and diarrhoea, perinatal death, stillborn fetus, miscarriage.Mesogenic and strong poison infect and have these symptoms above, and in swinery fast propagation of all ages.
Current; swine fever is still one of world's pig industry and threatens greatly .1997-1 all once repeatedly to break out swine fever in states such as Germany, Holland, Spain and Italy during 999 years; the phenomenon declined at persistent infection and the vaccine Vaccine effectiveness of Chinese CSFV is also commonplace; this not only causes serious economic loss to pig industry, and brings certain difficulty to swine fever control policy making.Also have the chemoprophylaxis treatment hog cholera wanting to close in prior art, but effect is all undesirable, and side effect is large.
Summary of the invention
The present invention, in order to solve the problem that effect of drugs is undesirable, side effect is large of existing Prevention hog cholera, provides a kind of Chinese medicine preparation for the treatment of initial stage hog cholera.
The present invention is realized by following technical scheme: a kind of Chinese medicine preparation for the treatment of initial stage hog cholera, is prepared from by the raw material of following weight fraction: Herba Ephedrae (processed) 45-55 part, Semen Armeniacae Amarum 45-55 part, Radix Platycodonis 45-55 part, Folium Eriobotryae 90-110 part, Bulbus Fritillariae Thunbergii 55-65 part, Radix Peucedani 25-35 part, Radix Glycyrrhizae Preparata 25-35 part, Gypsum Fibrosum 180-220 part, Radix Scutellariae 45-55 part, Herba Houttuyniae 180-220 part, Poria 90-110 part, Radix Stemonae 45-55 part, Herba Asari 28-32 part, Radix Glycyrrhizae 28-32 part.
Optimum ratio is: Herba Ephedrae (processed) 50 parts, 50 parts, Semen Armeniacae Amarum, Radix Platycodonis 50 parts, Folium Eriobotryae 100 parts, Bulbus Fritillariae Thunbergii 60 parts, Radix Peucedani 30 parts, Radix Glycyrrhizae Preparata 30 parts, Gypsum Fibrosum 200 parts, Radix Scutellariae 50 parts, Herba Houttuyniae 200 parts, 100 parts, Poria, the Radix Stemonae 50 parts, Herba Asari 30 parts, Radix Glycyrrhizae 30 parts.
The Chinese medicine preparation of described treatment initial stage hog cholera is powder: raw material pulverizing grinds to form mix homogeneously after 80-100 order, is added in feedstuff to feed amount the day of 1%---3%; The Chinese medicine preparation of described treatment initial stage hog cholera is water decoction: conventional decocting after material medicine mixing, adds 100ml medicine juice in every 1000ml water, freely drink.
In medicine of the present invention: Herba Ephedrae (processed): diaphoresis, relieving asthma, diuretic; The cold table that cures the wound is real, and fever with chills is lossless, headache nasal obstruction, arthralgia; Cough and asthma; Edema due to wind pathogen edema, dysuria; Ailment said due to cold or exposure insensitive impediment, munbness, rubella pruritus.Semen Armeniacae Amarum: expelling phlegm for arresting cough, relievings asthma, intestine moistening.Control exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation; Radix Platycodonis is bitter, pungent, flat; Return lung meridian; Lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.Folium Eriobotryae clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.Bulbus Fritillariae Thunbergii heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing, for wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore.Radix Peucedani falls apart wind heat clearing away, lowering the adverse-rising QI to resolve phlegm.For cough due to pathogenic wind-heat's abundant expectoration, expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.Radix Glycyrrhizae Preparata, Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Gypsum Fibrosum clearing away heat-fire, relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Herba Houttuyniae heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.The cough-relieving of Radix Stemonae nourishing the lung to keep the adverse QI downward, parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis; Outer for head louse, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For deficiency of YIN chronic cough.Herba Asari expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.All medicines are played altogether, treatment pestilence from the beginning of, card is shown in: cough, hyperpyrexia, shiver with cold, mouth breathing, rhinorrhea, argol yellowish urine be red, drink loss of appetite, there are petechia or ecchymosis in red red, the indivedual Pilus Sus domestica hole of skin.
Be very effective of the present invention, without any side effects, search for food without obvious negative effect to pig, have active influence to feed-weight ratio, and consumption is few, cost is low, is conducive to the income increasing pig farmer.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of initial stage hog cholera, is prepared from by the raw material of following weight portion: Herba Ephedrae (processed) 45 parts, 45 parts, Semen Armeniacae Amarum, Radix Platycodonis 45 parts, Folium Eriobotryae 110 parts, Bulbus Fritillariae Thunbergii 65 parts, Radix Peucedani 35 parts, Radix Glycyrrhizae Preparata 25 parts, Gypsum Fibrosum 180 parts, Radix Scutellariae 45 parts, Herba Houttuyniae 180 parts, 90 parts, Poria, the Radix Stemonae 45 parts, Herba Asari 28 parts, Radix Glycyrrhizae 28 parts.Raw material pulverizing grinds to form mix homogeneously after 80 orders, and the day with 3% feeds amount and is added in feedstuff.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of initial stage hog cholera, is prepared from by the raw material of following weight portion: Herba Ephedrae (processed) 50 parts, 50 parts, Semen Armeniacae Amarum, Radix Platycodonis 50 parts, Folium Eriobotryae 100 parts, Bulbus Fritillariae Thunbergii 60 parts, Radix Peucedani 30 parts, Radix Glycyrrhizae Preparata 30 parts, Gypsum Fibrosum 200 parts, Radix Scutellariae 50 parts, Herba Houttuyniae 200 parts, 100 parts, Poria, the Radix Stemonae 50 parts, Herba Asari 30 parts, Radix Glycyrrhizae 30 parts.Raw material pulverizing grinds to form mix homogeneously after 100 orders, and the day with 1% feeds amount and is added in feedstuff.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of initial stage hog cholera, is prepared from by the raw material of following weight portion: Herba Ephedrae (processed) 55 parts, 55 parts, Semen Armeniacae Amarum, Radix Platycodonis 55 parts, Folium Eriobotryae 90 parts, Bulbus Fritillariae Thunbergii 55 parts, Radix Peucedani 25 parts, Radix Glycyrrhizae Preparata 35 parts, Gypsum Fibrosum 220 parts, Radix Scutellariae 55 parts, Herba Houttuyniae 220 parts, 110 parts, Poria, the Radix Stemonae 55 parts, Herba Asari 32 parts, Radix Glycyrrhizae 32 parts.Be prepared as water decoction: conventional decocting after material medicine mixing, adds 100ml medicine juice in every 1000ml water, freely drink.
Compliance test result: select 200 ablactational baby pig from certain pig farm, be divided into four groups, four groups of piglets are without obvious ecological difference.One group of piglet conveniently feed mode is fed, as a control group; In its excess-three group pig starter feed, addition adds the Chinese medicine prepared by the embodiment of the present invention according to the rules, as experimental group.Feed to delivering for sale, two groups of feed-weight ratio difference are not obvious, and without obvious significant difference, statistics hog cholera sickness rate, hog cholera mortality rate, see the following form.
Project Matched group Embodiment 1 Embodiment 2 Embodiment 3
Hog cholera sickness rate/% 50 6 5 4
Hog cholera mortality rate/% 10 0 0 0

Claims (4)

1. treat a Chinese medicine preparation for initial stage hog cholera, it is characterized in that: be prepared from by the raw material of following weight portion: Herba Ephedrae (processed) 45-55 part, Semen Armeniacae Amarum 45-55 part, Radix Platycodonis 45-55 part, Folium Eriobotryae 90-110 part, Bulbus Fritillariae Thunbergii 55-65 part, Radix Peucedani 25-35 part, Radix Glycyrrhizae Preparata 25-35 part, Gypsum Fibrosum 180-220 part, Radix Scutellariae 45-55 part, Herba Houttuyniae 180-220 part, Poria 90-110 part, Radix Stemonae 45-55 part, Herba Asari 28-32 part, Radix Glycyrrhizae 28-32 part.
2. a kind of Chinese medicine preparation for the treatment of initial stage hog cholera according to claim 1, is characterized in that: be prepared from by the raw material of following weight portion: Herba Ephedrae (processed) 50 parts, 50 parts, Semen Armeniacae Amarum, Radix Platycodonis 50 parts, Folium Eriobotryae 100 parts, Bulbus Fritillariae Thunbergii 60 parts, Radix Peucedani 30 parts, Radix Glycyrrhizae Preparata 30 parts, Gypsum Fibrosum 200 parts, Radix Scutellariae 50 parts, Herba Houttuyniae 200 parts, 100 parts, Poria, the Radix Stemonae 50 parts, Herba Asari 30 parts, Radix Glycyrrhizae 30 parts.
3. a kind of Chinese medicine preparation for the treatment of initial stage hog cholera according to claim 1 and 2, it is characterized in that: the Chinese medicine preparation of described treatment initial stage hog cholera is powder: raw material pulverizing grinds to form mix homogeneously after 80-100 order, be added in feedstuff to feed amount the day of 1%---3%.
4. a kind of Chinese medicine preparation for the treatment of initial stage hog cholera according to claim 1 and 2, it is characterized in that: the Chinese medicine preparation of described treatment initial stage hog cholera is water decoction: conventional decocting after material medicine mixing, add 100ml medicine juice in every 1000ml water, freely drink.
CN201410726483.3A 2014-12-04 2014-12-04 A kind of Chinese medicine preparation for treating hog cholera at initial stage Active CN104491358B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104825769A (en) * 2015-04-30 2015-08-12 新昌县大成生物科技有限公司 Biological preparation for preventing swine fever
CN106668671A (en) * 2017-02-20 2017-05-17 天津市宁河区鑫瑞畜牧养殖场 Swine fever formula

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1453018A (en) * 2003-05-21 2003-11-05 西安碑林药业股份有限公司 Chinese medicine for treating children's dyspneic cough and its prepn
CN101422582A (en) * 2007-11-02 2009-05-06 天津瑞普生物技术集团有限公司 Traditional Chinese medicine oral liquid for treating livestock and poultry respiratory infection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1453018A (en) * 2003-05-21 2003-11-05 西安碑林药业股份有限公司 Chinese medicine for treating children's dyspneic cough and its prepn
CN101422582A (en) * 2007-11-02 2009-05-06 天津瑞普生物技术集团有限公司 Traditional Chinese medicine oral liquid for treating livestock and poultry respiratory infection

Non-Patent Citations (1)

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Title
吕国邦等: "猪高热病的中兽医防治", 《动物医学进展》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104825769A (en) * 2015-04-30 2015-08-12 新昌县大成生物科技有限公司 Biological preparation for preventing swine fever
CN106668671A (en) * 2017-02-20 2017-05-17 天津市宁河区鑫瑞畜牧养殖场 Swine fever formula

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