CN106615660A - Premix feed capable of preventing and curing porcine reproductive and respiratory syndrome (PRRS) of pregnant sows, and preparation method of premix feed - Google Patents
Premix feed capable of preventing and curing porcine reproductive and respiratory syndrome (PRRS) of pregnant sows, and preparation method of premix feed Download PDFInfo
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Abstract
The invention relates to premix feed capable of preventing and curing porcine reproductive and respiratory syndrome (PRRS) of pregnant sows. The premix feed is prepared from a nutrition additive, a Chinese herbal medicine additive and a diluent; the raw medicinal material content of the Chinese herbal medicine additive is 0.5-8% of the weight of the premix feed; the Chinese herbal medicine additive is prepared by extracting or directly grinding the following medicines in parts by weight: 0.5-3 parts of honeysuckle flower, 0.5-3 parts of herba houttuyniae, 0.5-3 parts of radix paeoniae rubra, 0.5-3 parts of radix astragali seu hedysari and 0.5-3 parts of cortex mori; the diluent is a mixture of zeolite powder and rice hull powder, wherein the weight ratio of the zeolite powder to the rice hull powder is equal to 1 to 1. The premix feed can meet vitamins, trace elements, amino acids and the like which are needed by staged growth and development of the pregnant sows, improves production efficiency and enhances immunity; the Chinese herbal medicine additive added into the premix feed has the functions of clearing away heat and toxic materials, eliminating carbuncle and removing pus, cooling blood and dispersing blood stasis, strengthening body resistance and dispelling evils, resisting bacteria and eliminating inflammation, and the like; therefore, the premix feed improves the body immunity, disease resistance and anti-stress ability of pigs, and has a remarkable effect for preventing and treating highly pathogenic PRRS.
Description
Technical field
The invention belongs to agriculture herding application, and in particular to a kind of premixed feed of preventing and treating in-pig indigo plant otopathy
And preparation method thereof.
Background technology
Pig blue-ear disease (PRRS) is caused with respiratory complication (being commonly called as blue otopathy) virus by pig breeding, belongs to artery
Scorching Viraceae, Arterivirus, with sow breeding difficulty, premature labor, miscarriage and stillborn foetus, piglet and bred pigs Respiratory symptoms
For principal character.Serious case may occur in which depressed, expiratory dyspnea etc., because of anoxic of having difficulty in breathing, causes have sharp ears, is presented blue in one's ear
Purple, therefore cry " blue otopathy ".
The multiple high temperature season for being born in spring Mo, early summer of pig high-pathogenicity blue ear disease, particularly severe in feeding environment, pig house
It is aeration-cooling bad, hot humid, the excessive raise family scattered of stocking density and small-sized pig farm it is multiple, infected pig is presented hyperpyrexia
(41 DEG C -42 DEG C), spirit is depressed, does not rise sleepingly, anorexia, rubefaction, eye conjunctivitis, palpebral edema；Asthma, stream nose
Tears, cough；There is constipation, diarrhoea；Part pig rear quarters is powerless, it is impossible to standing or incoordination etc..Infected in-pig essence
Refreshing depressed, off feed, temporary higher, the different degrees of expiratory dyspnea of body temperature, heat is abnormal or infertile, farrowing sow morning
Product, miscarriage, stillborn foetus, monster, weak tire etc..
For preventing and treating pig blue-ear disease, in addition to extremely product improves breeding environment, anti-pig blue-ear disease vaccine is exactly inoculated with.With regard to epidemic disease
Seedling is inoculated with, and highly effective immune me chanism measure is there is no at present, although released both at home and abroad commercialization PRRS attenuated vaccines and
Also there is the inactivated vaccine of official approval inactivated vaccine, the country.However, the enhanced phenomenon of reversion virulence and safety of PRRS attenuated vaccines
Sex chromosome mosaicism increasingly causes the worry of people.Have both at home and abroad and cause breaking out for a lot of PRRS in swinery using attenuated vaccine, because
This, should cautiously use live vaccine；And the immune efficacy of inactivated vaccine is extremely limited or uncertain, bring to preventing and treating pig blue-ear disease
Very big uncertainty.Chinese medicine be China traditional rarity, with a long history, wide material sources, cheap, Small side effects, Chinese medicine
The preventing and treating to Animal diseases in modern farming production is increasingly being used for, adding Chinese medicine in pig feed carries out spice, right
Prevention and treatment highly pathogenic PRRS has good effect.
The content of the invention
Present invention aim at offer is a kind of to educate sow compound premixed feed containing Chinese herbal medicine, the premixed feed nutrition
Equilibrium, can meet vitamin, the trace element required for the development of in-pig growth period, amino acid etc., its addition medium-height grass
Medicine honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry, effect is clearing heat and detoxicating, the carbuncle that disappears apocenosis, cool blood dissipates the stasis of blood, righting are got rid of evils, resisted
Bacterium anti-inflammatory, improves immunity of organisms, the resistance against diseases of pig, resisting stress, to prevent and treat highly pathogenic PRRS have it is aobvious
Write effect.
For achieving the above object, the present invention is adopted the following technical scheme that：
A kind of premixed feed of preventing and treating in-pig indigo plant otopathy, it is characterised in that the premixed feed adds containing nutritious
Plus agent, Chinese herb feed additive and diluent；The Chinese herb feed additive is the 0.5 of the weight of premixed feed containing raw medicinal herbs amount
～8%, it is made up of the extracted preparation of the medicine of following parts by weight or directly crushing：Honeysuckle 0.5-3 parts, cordate houttuynia
0.5-3 parts, radix paeoniae rubrathe 0.5-3 parts, Radix Astragali 0.5-3 parts, root bark of white mulberry 0.5-3 parts；The diluent is weight proportion zeolite powder：Rice husk
Powder=1:1 mixture.
Preferably, described Chinese herb feed additive is by the extracted preparation of medicine or direct crushing of following parts by weight
Made by mixture：1 part of honeysuckle, 1 part of cordate houttuynia, 1 part of the radix paeoniae rubrathe, 1 part of the Radix Astragali, 1 part of the root bark of white mulberry.
Further, the Chinese herb feed additive is the 1.5～6% of the weight of premixed feed containing raw medicinal herbs amount,
More preferably 2～5%.
Preferably, the nourishing additive agent be containing B B-complex, composite trace element, sodium chloride, compound amino acid,
The mixture of Choline Chloride and carrier components.
Further, the B B-complex includes vitamin A, vitamin D, vitamin E, vitamin K3, vitamin
B1, Cobastab2, Cobastab6, Cobastab12, nicotinic acid, D-VB5 calcium, folic acid, one or more of biotin；It is described compound micro-
Secondary element premixed feed includes one or more in copper, iron, manganese, zinc, iodine, solarization, cobalt, calcium；The compound amino acid includes
One or more of lysine, methionine.
The invention provides the preparation method of described milking sow premixed feed, it is characterised in that including following step
Suddenly：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, plus 8～12 times amount decoctings boil 2～3 times,
1～3 hour every time, merge decoction liquor, filter, be evaporated to relative density 1.15～1.27 (50 DEG C), drying under reduced pressure, powder
It is broken, 100 mesh sieves are crossed, obtain Chinese herb feed additive；
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative bag
Dress up premixed feed.
Present invention also offers the application of described premixed feed, it is characterised in that：In in-pig stage, addition weight
Amount percentage composition is perfect compound feed prepared by 4% above-mentioned premixed feed.
From in terms of Chinese veterinarian's angle, pig blue-ear disease belongs to Epidemic Febrile Disease, and " mutual aid of empty heresy " is predisposing factors i.e. traditional Chinese medical science institute
Virus is taken advantage of a weak point when the five internal organs said are in " void ", cause it is evil win just decline, it is disease-resistant powerless；The sick summer is multiple, more because diseases caused by external factors are wet
Thermalization fire, causes Lung Qi obstruction, disturbance in ascending and descending, imbalance of yin and yang.Case change is mainly lung and sticks together with pleura, lung swelling,
Lung has dispersivity bleeding, in interstitial pneumonia, some lung atrophys, in meat sample denaturation, serious loss gas exchange capacity；Tracheae,
There are the foam-like mucus or faint yellow purulence mucus of volume in bronchus.The notable swelling of inguinal lymph nodes, tangent plane moistening are turned up,
Congested, bleeding is serious, lymphonodi mesenterici, hilar lymph node obvious tumefaction, in khaki or kermesinus.The Ying Yiqing in treatment
Thermal detoxification, the carbuncle that disappears apocenosis, cool blood dissipates the stasis of blood, anti-inflammation strengthens pig resistance.
The each Pharmaceutical Analysis of the present invention：
Honeysuckle：Gas delicate fragrance, lightly seasoned, slight bitter.It is sweet, tremble with fear.Return lung, the heart, stomach.Function is clearing heat and detoxicating, wind-heat dissipating.For
Carbuncle swells furunculosis. larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm disease heating.《Explaining abstruseness of the canon of materia medica》：Honeysuckle, main turgor diarrhea, disappears
Carbuncle dissipates poison, and qi-restoratives treats wind, common people but knows the work(of its sterilization, hides its swollen sharp wind void and is used, and with it in all diseases of minor, takes effect repeatedly.
《The southern regions of the Yunnan Province book on Chinese herbal medicine》：Heat-clearing, solves all sores, ulcer carbuncle on the back, pellet stream scrofula.《The sward property of medicine is standby will》：The ulcer that can disappear serious case of furuncle, only dysentery,
Infantile malnutrition due to digestive disturbances or intestinalparasites sore is washed, skin blood-head is gone.《Essentials of Materia Medica》：Blood-nourishing is quenched the thirst.Control mange.《Chongqing hall random notes》：Clear network apoplexy fire is damp and hot, Xie Wen
The dirty filthy heresy of epidemic disease, the floating more wind sun of breath liver and gall is controlled convulsion and is fainted all diseases of epilepsy.Guangzhou army《Conventional Chinese herbal medicine handbook》：It is clearing heat and detoxicating.Control
Fever caused by exogenous pathogens is coughed, enteritis, bacillary dysentery, measles, parotitis, septicemia, sore furuncle poison, appendicitis, trauma infection contamination, children's miliaria poison.
Cold tea is made, heatstroke, flu and enteric infectious disease can be prevented.
Cordate houttuynia：Fresh herb for saururaceae plant houttuynia cordata HouttuyniacordataThunb. is dryly gone up
Partly, fresh goods is annual can tap；The luxuriant flower spike of dry product summer cauline leaf is tapped when many, removes impurity, is dried.It is pungent, it is slightly cold.Return lung
Jing.It is clearing heat and detoxicating, the carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia.For lung carbuncle pyemesis, phlegm heat panting is coughed, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus.《The southern regions of the Yunnan Province
Book on Chinese herbal medicine》：Lung carbuncle cough band purulence blood is controlled, phlegm has stench, and large intestine heat toxin treats hemorrhoid.《Compendium of Materia Medica》：The malicious carbuncle swells of radiating, sore hemorrhoid take off
Anus, shop disease of breaking, Nao is malicious for solution.《Medical center bun will》：Water-filling, assaults fortified position, and removes miasma, relieving summer-heat.Snakeworm poison is treated, tinea pedis is controlled, ulcer of bursting, stasis eliminatings
Blood.《Classification is herbal》：Five pouring are controlled, consumer edema goes dyspepsia, and qi-restoratives is weak, and disappear expansion.《The south of the Five Ridges is gathered medicinal herbs record》：Leaf：Apply vicious big
Sore, can sterilize；Decoction energy remuval of damp and hot, controls dysentery.Guangzhou air force《Conventional Chinese herbal medicine handbook》：Eliminating inflammation and expelling toxin, inducing diuresis to remove edema.Control
Respiratory tract infection, lung abscess, urinary tract inflammation and other position purulent inflammations, venomous snake bite.Guangzhou army《Conventional Chinese herbal medicine hand
Volume》：It is clearing heat and detoxicating.Control mastitis, cellulitis, tympanitis, enteritis.
The radix paeoniae rubrathe：This product is ranunculaceae plant Chinese herbaceous peony PaeonialactifloraPall. or the river radix paeoniae rubrathe
The dry root of PaeoniaveitchiiLynch.Gas micro-perfume, it is mildly bitter flavor, sour and astringent.Hardship, is slightly cold.Return liver warp.Effect clearing heat and cooling blood,
Blood stasis removing analgesic.For febrile virulent maculae, hematemesis and epistaxis, hot eyes tumour, liver-depressed hypochondrium pain, Amenorrhea dysmenorrhoea ， Disorder lump in the abdomen is suffered from abdominal pain, injury from falling down,
Carbuncle swells sore.《The new compilation of materia medica》：Chinese herbaceous peony, red scattered heresy is stagnant in energy blood.《This Jing》：Main perverse trend stomachache, except blood-arthralgia, breaks hard product, trembles with fear
Hot hernia lump in the abdomen, pain relieving, diuresis, beneficial gas.《Do not record》：Clear and coherent blood vessels, in delaying, dispelling malignant blood, expelling extravasated blood goes aqueous vapor, sharp bladder size
Intestines, subduing inflammation, when row fever and chills, middle evil stomachache, pain in the back.《Haigoushen》：Lung perverse trend is controlled, a surname's internal organs are led in Fu Zhong Xu pains, vim and vigour accumulation
Gas is gathered around, evil pain sepsis is controlled, disease bone heat, strong the five internal organs, kidney tonifying gas, control that trusted subordinate's heavily fortified point is swollen when main, and married woman's blood closes obstructed, disappear the stasis of blood blood, can lose
Purulence.《Japan hanako materia medica》：Control wind mend labor, main woman all it is sick and it is antenatal after all diseases, Tong Yueshui, relieving restlessness of bringing down a fever, beneficial gas, day row heat
Disease, pest miasma shies mad, married woman's blood fortune, and intestines wind rushes down blood；Hemorrhoid complicated by anal fistula, carbuncle on the back, sore scabies, headache, improving eyesight, hot eyes, the triangular mass of mucous membrane growing from the inner corner of the eye.《The southern regions of the Yunnan Province sheet
Grass》：Spleen fire is rushed down, sending down abnormally ascending, promoting circulation of blood, broken stasis of blood dissipates clot, only suffers from abdominal pain, and moves back blood-head, attacks ulcerative carbuncle, controls scabies leprosy.《Medicineization justice》：Purging the liver of pathogenic fire
Fire.
The root bark of white mulberry：This product is the dry root skin of moraceae plants mulberry MirusalbaL..Last years in autumn falling to adopted before secondary spring germination
Uproot portion, scrape off yellowish-brown tertia.Cut open longitudinal direction.Root skin is stripped, is dried.Gas is micro-, taste micro-sweet.It is sweet, tremble with fear.Return lung Jing.Purging the lung of pathogenic fire is put down
Breathe heavily, inducing diuresis for removing edema.For dyspnea and cough due to lung-heat, oedema turgor oliguria, appearance skin edema.《This Jing》：In main wound, exhaustion or lesion of the five internal organs sextupole is thin
Thin, metrorrhagia, arteries and veins is exhausted, tonify deficiency benefit health.《Do not record》：Aqueous vapor in lung is gone, spitting blood, heat is thirsty, and oedema, abdomen completely sets out swollen, dredging water passages, gone very little
In vain, metal-inflicted wound can be stitched.《Haigoushen》：Control lung qi and breathe heavily full, aqueous vapor edema, main wound is exhausted, dredging water passages, and disappear aqueous vapor, consumptive disease visitor's heat, head
Bitterly, interior tonifying for the deficiency.《The southern regions of the Yunnan Province book on Chinese herbal medicine》：Only cough with lung heat.《Detailed outline》：Purging the lung of pathogenic fire, sending down abnormally ascending dissipates blood.
The Radix Astragali：Gas is micro-, and taste is micro- sweet, and that what is chewed micro- has beany flavor.It is sweet, temperature.Return lung, the spleen channel.Invigorating qi for strengthening superficies, diuretic and maintain drug, row
Purulence, expelling pus and promoting granulation.For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy water
It is swollen, ulcer is difficult to burst, bursts for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；Chronic rephrilis protinuria, diabetes.《Bencao Jingshu》：Function
Real table, has table heresy person not use；Gas can be helped, gas reality person do not use；Interior can fill in, tonifying for the deficiency, chest diaphragm is gas-tight to ask, stomach has stagnant person not
With；Energy yang-tonifying, overabundance of YANG leading to deficiency of YIN person avoids it；Part of the body cavity above the diaphragm housing the heart and lungs heat is contained, and lower burnt cold of insufficiency type person avoids it；The many anger of patient, irritability discord person do not take；Variola
Blood system heat is notably disabled.
The premixing flour of the present invention be referred to the swine rearing standard that the Ministry of Agriculture 2004 promulgates and《Chinese feed ingredient
And nutritive value table (2016 the 27th edition)》Prepared, added nourishing additive agent, to meet the development of in-pig growth period
Required vitamin, trace element, amino acid etc..
The raw material composition of the nourishing additive agent：Vitamin A, vitamin D, vitamin E, vitamin K3, Cobastab1, dimension life
Plain B2, Cobastab6, Cobastab12, nicotinic acid, D-VB5 calcium, folic acid, biotin, Choline Chloride, 1B, DL- METHIONINE,
Cupric sulfate pentahydrate, ferrous sulfate monohydrate, manganese sulfate monohydrate, monohydrate zinc sulphate, 1% sodium selenite, 1% KI, cobalt chloride, stone
Powder, calcium monohydrogen phosphate, sodium chloride.Its product composition table is as follows：
Its product composition analysis guarantee value table of table 1
| Vitamin A (ten thousand IU) | 20-25 | Iron g | 1.75-2.25 |
| Vitamin D (ten thousand IU) | 2.0-10 | Manganese g | 0.2-3.5 |
| Vitamin E IU | 1125-1875 | Zinc g | 1-1.5 |
| Vitamin K3mg | 12.5-250 | Iodine mg | 3.5-125 |
| Cobastab1mg≥ | 44 | Selenium mg | 2.5-10 |
| Cobastab2mg≥ | 132 | Cobalt mg | 2.5-45 |
| Cobastab6mg≥ | 41.25 | Lysine % >= | 3.0 |
| Cobastab12mg≥ | 0.495 | Sodium chloride % | 6-32.5 |
| Folic acid mg >= | 82.5 | Calcium % | 12-22 |
| Nicotinic acid mg >= | 605 | Total phosphorus % >= | 2.0 |
| Biotin mg >= | 11 | Methionine % >= | —— |
| Pantothenic acid mg >= | 412.5 | Phytase KIU >= | 10 |
| Choline g >= | 28.75 | Copper g | 0.125-0.85 |
【Carrier】Zeolite powder, powdered rice hulls, honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali, the root bark of white mulberry.
The premixed feed for obtaining is prepared according to the method described above not directly to feed, and should be mixed with corn, dregs of beans etc. and be made
Mixed feed is used.This product can meet vitamin, the trace element required for the development of in-pig growth period, amino acid
Deng improve production efficiency.Mixed feed recommended formula is as shown in table 2：
Mixed feed recommended ratio table of table 2 (in terms of parts by weight)
| Raw material | Corn | Dregs of beans | Wheat bran | Premixed feed | It is total |
| Recommended formula | 60 | 14 | 22 | 4 | 100 |
Beneficial effects of the present invention：
1) premixed feed of the present invention using chemically stable, can not with microcomponent reaction material as carrier or dilution
Agent, zeolite meal component is mainly silicates, to ph stability, therefore can guarantee that the stability of trace element, micro- so as to ensure that
The quality of secondary element premixed feed.Test shows that, using zeolite powder and powdered rice hulls as carrier, its moisture is low, acid for the present invention
Basicity is close to that neutral, granularity is moderate, bearing capacity is strong, unit weight and microcomponent is close and low cost, can guarantee that microcomponent is equal
It is even to be mixed in feed, proportioning accuracy and dispensing speed are improved, while by the scientifical use to carrier or diluent, can solve
Certainly physicochemical property is inconsistent between the stability difference and various additives of some microcomponents and influencing each other of causing.
2) premixed feed of the invention addition Chinese herbal medicine honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry, with clear
Thermal detoxification, the carbuncle that disappears apocenosis, cool blood dissipates the stasis of blood, righting are got rid of evils, anti-inflammation function, improve immunity of organisms, the resistance against diseases of pig, are resisted
, stress there is remarkable result to preventing and treating highly pathogenic PRRS.Raw material sources of the present invention are wide, the letter of low cost, technique
Single, pig feed of the present invention can be good at preventing and treating the generation of pig blue-ear disease, it is ensured that the Jing of raiser and breeding enterprise
Ji income, with good economic benefit and social benefit, is conducive to the sound development of aquaculture.
Specific embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
Prescription：Honeysuckle 500g, cordate houttuynia 500g, radix paeoniae rubrathe 500g, Radix Astragali 500g, root bark of white mulberry 500g.
Preparation process is as follows：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, plus 12 times of amount decoctings are boiled 3 times, every time 1 is little
When, merge decoction liquor, filter, relative density 1.15～1.27 (50 DEG C) is evaporated to, drying under reduced pressure is crushed, and crosses 100 mesh
Sieve, obtains Chinese herb feed additive；
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative bag
Dress up premixed feed.
Embodiment 2
Prescription：Honeysuckle 750g, cordate houttuynia 750g, radix paeoniae rubrathe 40g, Radix Astragali 300g, root bark of white mulberry 300g.
Preparation process is as follows：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, plus 8～12 times amount decoctings boil 2～3 times,
1～3 hour every time, merge decoction liquor, filter, be evaporated to relative density 1.15～1.27 (50 DEG C), drying under reduced pressure, powder
It is broken, 100 mesh sieves are crossed, obtain Chinese herb feed additive；
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative bag
Dress up premixed feed.
Embodiment 3
Prescription：Honeysuckle 400g, cordate houttuynia 600g, radix paeoniae rubrathe 700g, Radix Astragali 400g, root bark of white mulberry 400g.
Preparation process is as follows：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, is mixed, crushed, 100 mesh sieves are crossed, in obtaining
Chinese herbal medicine additive agent.
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative bag
Dress up premixed feed.
Embodiment 4
Prescription：Honeysuckle 400g, cordate houttuynia 400g, radix paeoniae rubrathe 600g, Radix Astragali 700g, root bark of white mulberry 400g.
Preparation process is as follows：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, plus 8 times of amount decoctings are boiled 3 times, every time 2 is little
When, merge decoction liquor, filter, relative density 1.15～1.27 (50 DEG C) is evaporated to, drying under reduced pressure is crushed, and crosses 100 mesh
Sieve, obtains Chinese herb feed additive；
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative bag
Dress up premixed feed.
Embodiment 5
Prescription：Honeysuckle 400g, cordate houttuynia 600g, radix paeoniae rubrathe 500g, Radix Astragali 500g, root bark of white mulberry 500g.
Preparation process is as follows：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, plus 10 times of amount decoctings are boiled 2 times, every time 3 is little
When, merge decoction liquor, filter, relative density 1.15～1.27 (50 DEG C) is evaporated to, drying under reduced pressure is crushed, and crosses 100 mesh
Sieve, obtains Chinese herb feed additive；
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative bag
Dress up premixed feed.
Experimental example 1：Therapeutic action of the premixed feed of the present invention to the pig blue-ear disease of in-pig
1. materials and methods
1.1 trial drugs
Trial drug is that premixing prepared by premixed feed prepared by the embodiment of the present invention 1 and the embodiment of the present invention 3 is raised
Material；Control drug is commercially available circle indigo plant health.
1.2 experimental animals
60 in-pigs of natural infection pig blue-ear disease.
In March, 2015,100 bull in-pig sudden onset of Beijing plant, body temperature rises up to more than 40 DEG C, eye
, there is different degrees of expiratory dyspnea symptom in conjunctiva inflammation, palpebral edema, spiritual depressed, poor appetite or useless exhausted, heating.Root
According to incidence, clinical symptoms and pathological change, the tentative diagnosis swinery is blue otopathy poison infection.Select wherein body weight Yue Age phases
Closely, the typical sow of the state of an illness 60 is tested, and observes the clinical efficacy of premixed feed of the present invention.
1.3 test methods
60 sick pigs are randomly divided into 3 groups, 20 per group.The 1st group of premixed feed prepared for the embodiment of the present invention 1
Group, is mixed with common daily ration with 4% ratio, 1 day 1 time, is concentrated and is thrown clothes, is used in conjunction 3～5 days；2nd group is made for the embodiment of the present invention 3
Standby premixed feed group, is mixed with common daily ration with 4% ratio, 1 day 1 time, is concentrated and is thrown clothes, is used in conjunction 3～5 days；3rd group is circle
Blue health control group, usage and dosage is 100g spice 200kg, once a day, concentrates and throws clothes, is used in conjunction 3-5 days.It is dynamic to all tests
Thing, Continuous Observation 15 days during medication and after medication record daily death toll, symptom change, drink, are intended to and the feelings such as state of mind
Condition.
1.4 curative effect determinate standards are invalid：
In administration and observation period, it is invalid to be considered as without effect or DeGrain；
Effectively：Various clinical symptom remissions in administration and observation period, hypothermia, palpebral edema, skin color, breathing are tired
Difficult and nervous symptoms etc. take a turn for the better, and the state of mind takes a turn for the better, and appetite increases, or the pig cured completely is accordingly to be regarded as effectively；
Cure：Various clinical symptom disappearances, body temperature, breathing recover normal, and appetite, the state of mind are good, after being discontinued one week
Do not recur.
2. test results and analysis
Result of the test see the table below.Test data carries out variance analysis using SPSS12.0 softwares, and result of the test data are entered
Row significance test.
The therapeutic effect of the pig blue-ear disease of table 3
Result of the test finds：In process of the test, the pig of test group of the present invention is too anxious because falling ill except testing 2 pigs of initial stage
Dead outer, other pigs all survive and take a turn for the better, and it is 90% that the embodiment of the present invention 1 prepares the total effective rate of medication therapy groups, is cured
Rate is 80%；The embodiment of the present invention 3 prepares the total effective rate 80% of medication therapy groups, and cure rate is 75%；Circle indigo plant health control group
Total effective rate is 85%, and cure rate is also only 70%.As can be seen from the test results, the effect of front 2 groups of medication groups with 3rd group pair
It is similar according to group effect, but the difference of Jing x2 inspections, test group and control group is not significantly (P >=0.05), i.e., it is obvious without statistics
Difference, illustrating the Chinese medicine compound pharmaceutical composition of the present invention can treat both principal and secondary aspect of disease, and have splendid to this kind of fever caused by exogenous pathogens disease of pig blue-ear disease
Curative effect.
Experimental example 2：Prevention effect of the premixed feed of the present invention to the pig blue-ear disease of in-pig
Sow due to farrow 60 is taken, three groups are divided at random, 20 per group, 1 group is normally fed, and 2,3 groups respectively in every pig
The embodiment 1 of weight percentage 4% and the premixed feed of embodiment 3 are added in daily feed.
2 Zhou Tianhou are raised, it is each in 2 groups respectively to add a pig with pig blue-ear disease, observe the farrowing of each group sow
Situation, the results are shown in Table 4.
Prevention effect of the premix of the present invention of table 4 to the pig blue-ear disease of sow
As a result show, the premixed feed of the present invention has obvious preventive and therapeutic action to pig blue-ear disease to sow.
Although the present invention is described in detail above to have used general explanation and specific embodiment, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
Without departing from theon the basis of the spirit of the present invention these modifications or improvements, belong to the scope of protection of present invention.
Claims (8)
1. it is a kind of preventing and treating in-pig indigo plant otopathy premixed feed, it is characterised in that the premixed feed contain nutritious addition
Agent, Chinese herb feed additive and diluent；Containing the weight that raw medicinal herbs amount is premixed feed the 0.5 of the Chinese herb feed additive～
8%, it is made up of the extracted preparation of the medicine of following parts by weight or directly crushing：Honeysuckle 0.5-3 parts, cordate houttuynia 0.5-
3 parts, radix paeoniae rubrathe 0.5-3 parts, Radix Astragali 0.5-3 parts, root bark of white mulberry 0.5-3 parts；The diluent is weight proportion zeolite powder：Powdered rice hulls=
1:1 mixture.
2. it is according to claim 1 preventing and treating in-pig indigo plant otopathy premixed feed, it is characterised in that：Described medium-height grass
Medicine additive be by the extracted preparation of the medicine of following parts by weight or directly crush and made by mixture：1 part of honeysuckle, fish
1 part of raw meat grass, 1 part of the radix paeoniae rubrathe, 1 part of the Radix Astragali, 1 part of the root bark of white mulberry.
3. it is according to claim 1 preventing and treating in-pig indigo plant otopathy premixed feed, it is characterised in that：The Chinese herbal medicine
Additive is the 1.5～6% of the weight of premixed feed containing raw medicinal herbs amount.
4. it is according to claim 1 preventing and treating in-pig indigo plant otopathy premixed feed, it is characterised in that：The Chinese herbal medicine
Additive is the 2～5% of the weight of premixed feed containing raw medicinal herbs amount.
5. it is according to claim 1 preventing and treating in-pig indigo plant otopathy premixed feed, it is characterised in that：The nutrition adds
Plus agent is mixed containing B B-complex, composite trace element, sodium chloride, compound amino acid, Choline Chloride and carrier components
Compound.
6. it is according to claim 5 preventing and treating in-pig indigo plant otopathy premixed feed, it is characterised in that：The compound dimension
Raw element includes vitamin A, vitamin D, vitamin E, vitamin K3, Cobastab1, Cobastab2, Cobastab6, Cobastab12、
Nicotinic acid, D-VB5 calcium, folic acid, one or more of biotin；The composite trace element premixed feed include copper, iron, manganese,
One or more in zinc, iodine, solarization, cobalt, calcium；The compound amino acid include lysine, one or more of methionine.
7. the preparation method of milking sow premixed feed according to claim 1, it is characterised in that including following step
Suddenly：
1) recipe quantity honeysuckle, cordate houttuynia, the radix paeoniae rubrathe, the Radix Astragali and the root bark of white mulberry are weighed, plus 8～12 times of amount decoctings boil 2～3 times, every time 1
～3 hours, merge decoction liquor, filter, be evaporated to relative density 1.15～1.27 (50 DEG C), drying under reduced pressure is crushed, mistake
100 mesh sieves, obtain Chinese herb feed additive；
2) zeolite powder and powdered rice hulls are crushed respectively, by weight 1:1 mixing, crosses 30-80 mesh sieves, as diluent；
3) by Chinese herb feed additive, nourishing additive agent and diluent, put in stainless steel mixer and stir and evenly mix, by quantitative package into
Premixed feed.
8. the application of premixed feed according to claim 1, it is characterised in that：In the in-pig stage, add weight
Percentage composition is perfect compound feed prepared by 4% above-mentioned premixed feed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611258851.1A CN106615660A (en) | 2016-12-30 | 2016-12-30 | Premix feed capable of preventing and curing porcine reproductive and respiratory syndrome (PRRS) of pregnant sows, and preparation method of premix feed |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611258851.1A CN106615660A (en) | 2016-12-30 | 2016-12-30 | Premix feed capable of preventing and curing porcine reproductive and respiratory syndrome (PRRS) of pregnant sows, and preparation method of premix feed |
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ID=58838470
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111467393A (en) * | 2020-05-26 | 2020-07-31 | 浙江中法制药有限公司 | Traditional Chinese medicine composition, pig feed additive and application of pig feed additive in preparation of control agent for porcine reproductive and respiratory syndrome or swine fever |
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| CN101019608A (en) * | 2007-03-16 | 2007-08-22 | 狄惠明 | Chinese herbal medicine mixture for feed |
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| CN106071059A (en) * | 2016-06-28 | 2016-11-09 | 白会娟 | A kind of pig feed preventing kind of pig blue-ear disease and preparation method thereof |
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2016
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| CN101019608A (en) * | 2007-03-16 | 2007-08-22 | 狄惠明 | Chinese herbal medicine mixture for feed |
| CN101584747A (en) * | 2009-06-29 | 2009-11-25 | 北京大北农科技集团股份有限公司 | Antibacterial antivirus Chinese medicinal composition for animal |
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| CN111467393A (en) * | 2020-05-26 | 2020-07-31 | 浙江中法制药有限公司 | Traditional Chinese medicine composition, pig feed additive and application of pig feed additive in preparation of control agent for porcine reproductive and respiratory syndrome or swine fever |
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