CN104435907A - Compound fermented Chinese medicine for livestock fattening and preparation method of compound fermented Chinese medicine - Google Patents

Compound fermented Chinese medicine for livestock fattening and preparation method of compound fermented Chinese medicine Download PDF

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Publication number
CN104435907A
CN104435907A CN201410829624.4A CN201410829624A CN104435907A CN 104435907 A CN104435907 A CN 104435907A CN 201410829624 A CN201410829624 A CN 201410829624A CN 104435907 A CN104435907 A CN 104435907A
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parts
chinese medicine
fattening
composition
preparation
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Inventor
杨荣恩
陈文萍
吴庭才
唐光武
伦柏楠
郝伟
崔学仁
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HENAN TANATU BIOTECHNOLOGY CO Ltd
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HENAN TANATU BIOTECHNOLOGY CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/34Copper; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

A compound fermented Chinese medicine for livestock fattening is characterized by comprising, by weight, 20-25 parts of hawthorn, 10-12 parts of symplectic leaves, 8-10 parts of red beans, 8-10 parts of soybeans, 10-12 parts of cyrtomium fortunei, 15-20 parts of malt, 10-12 parts of gelsemium elegans, 8-10 parts of polygonum multiflorum, 8-10 parts of astragalus, 8-10 parts of spine date seeds, 10-12 parts of glossy privet fruits, 20-25 parts of orange peel, 10-12 parts of schisandrae fruits, 20-25 parts of dyer woad leaves, 15-20 parts of empress tree leaves, 20-25 parts of pine needle powder, 8-10 parts of fructus cannabis, 5-8 parts of ferrous sulfate, 3-5 parts of copper sulfate, 5-8 parts of salt and 3-5 parts of multi-fibers. The compound fermented Chinese medicine has the functions of tonifying spleen, promoting appetite and rapidly fattening, livestock body spleen and stomach functions are enhanced, the livestock appetite is effectively enhanced, feed conversion ratio is increased, rapid fattening of livestock is promoted, potential safety hazards caused by chemical drugs are relieved by pure Chinese medicines, and medicine taking safety is improved. Medicine effects are rapidly produced, side effects are small, application time is short, and the compound fermented Chinese medicine is convenient to use.

Description

A kind of compound fermentation type Chinese medicine of fattening for poultry and preparation method thereof
Technical field
The present invention relates to a kind of compound fermentation type Chinese medicine of fattening for poultry and preparation method thereof.
Background technology
Along with the development of modern farming, on the one hand due to the reasons such as environmental stress, epidemic disease, feeding and management low SI, trophic structure are unreasonable, the limitation of breeding technology very easily cause that appetite of livestock and poultry is not good, feed intake decline, feed conversion rate reduction, nutritional imbalance etc., thus make raising poultry nutritive bad, build slight of stature, poor growth; On the other hand because of the needs of Modern Animal Husbandry, in order to improve the economic benefit of plant, improve the speed of production of poultry as much as possible, to improve the output of meat, eggs and milk.This technology is intended to poultry and fattens.
Herbal medicine is resist exopathogenic factor invade the QI and blood caused change by cultivating vigour in body substantially, fundamentally can improve body constitution and promote the growth of rehabilitation and histoorgan.And modern age, doctor trained in Western medicine advocated solution disease for first, alleviated apparent.Positive so-called Western medicine bactericidal antiphlogistic is controlled " mark ", Chinese medicine enhancing body anti pathologic immunity function, is positive controlling " basis ".Chinese medicine is natural green medicine, not easily causes receptor drug resistance and sequela, noresidue, ensures food safety.Improve absorbing of its effective ingredient by the fermentation of microbial ecological agent simultaneously.
Veterinary is common often uses Chinese powder medicine and oral liquid etc., and compound fermentation Chinese medicine is a kind of novel special dosage form on veterinary drug.Modern herbal medicine theory is pointed out, a herb has nearly more than 300 plants active ingredient, usually can not play its due effect completely, can only do some make up by escalated dose, cause and utilize herbal medicine disease therapy high cost.The physiological characteristics intestinal of birds is short and small in addition, and content excreted at 3-4 hour, and make absorption not thorough, trap only has about 30%.And fermented type Chinese medicine is almost all absorbed in section at this moment.Compound fermentation Chinese medicinal ointment be Chinese herbal medicine through ultrasonic grinding, then add compound bacteria-fermented and form, the efficient composition such as albumen, tannin, starch in not removed Chinese herbal medicine, and these compositions play vital effect in treatment of diseases.Be converted into the composition that body is convenient to absorb simultaneously with microbial action, accelerate health care and treatment speed, improve health-care effect and curative effect, improve the microecological environment of body, improve animal spontaneous recovery and resistance against diseases, improve animal feed rate of returns.As can be seen here, compound fermentation Chinese medicine is greatly be better than other form of Chinese drug on pharmacological effect.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, be provided for compound fermentation type Chinese medicine that poultry fatten and preparation method thereof.
For achieving the above object, the present invention is by the following technical solutions:
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 20-25, Xin Ye 10-12, Semen Phaseoli 8-10, Semen Glycines 8-10, Rhizoma Osmundae 10-12, Fructus Hordei Germinatus 15-20, Herba Gelsemii Elegantis 10-12, Radix Polygoni Multiflori 8-10, Radix Astragali 8-10, Semen Ziziphi Spinosae 8-10, Fructus Ligustri Lucidi 10-12, Pericarpium Citri Reticulatae 20-25, Fructus Schisandrae Chinensis 10-12, Folium Isatidis 20-25, Folium paulowniae 15-20, pine needle powder 20-25, Fructus Cannabis 8-10, ferrous sulfate 5-8, copper sulfate 3-5, Sal 5-8, multidimensional 3-5.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 20-80 object sieve and carries out preliminary treatment;
Step 2, each composition step one handled well mixes, and then to add weight portion be that the composite bacteria liquid of 2-3 mixes, and at the culture medium top fermentation 16-18 hour of 35-37 DEG C, adds stabilizing agent mixing and save backup after being cooled to 20-25 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 20-30%, bean cake 3-4%, ammonium sulfate 1-2%, magnesium sulfate 0.5-1%, calcium carbonate 1-2% and water 20-30%.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.05-0.08% and antioxidant propyl gallate 0.008-0.01%.
In described step 2, extracting lactic acid bacterium, yeast, streptococcus faecalis and bacillus cereus carry out slant strains cultivation as strain to the concrete preparation method of composite bacteria liquid: a. respectively respectively, is added to increase in bacterium cultured solution of broth after the bacterium colony normal saline eluting that often kind of slant culture is produced and make suspension, and then amplification culture is distinguished in appropriate media, be cultured to exponential phase 0.5 × 10 8cFU/mL to 1.0 × 10 8during CFU/mL only; B. the lactobacillus suspension, yeast liquid, streptococcus faecalis liquid and the bacillus liquid that are obtained by step a are according to 2:(1-2): 1:1 ratio is mixed to get composite bacteria liquid.
The pharmacological action of Chinese medicine of the present invention is as follows:
Fructus Crataegi: acid is sweet, tepor.Enter spleen, stomach, Liver Channel.Help digestion long-pending, dissipating blood stasis blood, expelling tenia.
Xin Ye: toil, tepor, slightly poisonous.Invigorate blood circulation, dissipating blood stasis, removing toxic substances of dispeling the wind.
Semen Phaseoli: property is put down, sweet in the mouth, acid, can inducing diuresis and reducing edema, heat clearing away jaundice eliminating, removing toxic substances and promoting pus discharge.
Semen Glycines: sweet in the mouth, property are flat, enter spleen, large intestine channel, can kill Aconitum carmichjaelii Debx., Radix Aconiti Lateralis Preparata poison; There is spleen invigorating alleviating distention in middle-JIAO, moisturize effect of the water that disappears, heat-clearing and toxic substances removing, QI invigorating
Rhizoma Osmundae: bitter, puckery, is slightly cold.Enter liver, stomach warp.Kill ascarid, silk ribbon, pinworm, heat clearing away, removing toxic substances, removing heat from blood, hemostasis.
Fructus Hordei Germinatus: slightly warm in nature.Return spleen, stomach, Liver Channel.Energy digesting and appetizing, and in, galactopoiesis.
Herba Gelsemii Elegantis: removing mass is drawn out pus by applying a plaster to the affected part, stasis-dispelling and pain-killing, killing parasites for relieving itching, analgesia.
Radix Polygoni Multiflori: bitter sweet puckery, tepor.Enter liver, kidney channel.Nourishing the blood and yin; Loosening bowel to relieve constipation; Preventing the attack (or recurrence) of malaria; Dispel the wind; Removing toxic substances.
The Radix Astragali: nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Semen Ziziphi Spinosae: sweet is flat.Gui Jing; Spleen channel, Liver Channel, gallbladder meridian.Mind tranquilizing and the heart calming; Nourishing the liver; Arresting sweating.
Fructus Ligustri Lucidi: sweet is bitter, flat.Return liver; Kidney channel.Liver and kidney tonifying, clearind deficient heat, strong waist knee joint, improve visual and auditory acuity, black beard and hair.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Astringe the lung, nourishing kidney, promotes the production of body fluid, and receives antiperspirant, arresting seminal emission.
Folium Isatidis: bitter in the mouth, cold in nature.Return liver, the heart, stomach, spleen channel.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.
Folium paulowniae: bitter in the mouth; Cold in nature.Main carbuncle; Furuncle swelling toxin; Wound hemorrhage.
Pine needle powder: bitter, puckery, temperature.Enter liver, kidney, lung, spleen channel.Expelling wind and activating blood circulation, improving eyesight, calms the nerves, removing toxic substances, antipruritic.
In formula of the present invention, Fructus Crataegi, Xin Ye, Semen Phaseoli are monarch drug, and three tastes share, heat clearing away dissipating blood stasis, invigorating the stomach and promoting digestion; Radix Polygoni Multiflori, the Radix Astragali, Semen Ziziphi Spinosae, Fructus Ligustri Lucidi are adjuvant drug, the sweet tepor of Fructus Schisandrae Chinensis, Folium Isatidis, Folium paulowniae hardship are cool, heat-clearing and toxic substances removing, to promote the production of body fluid hemostasis, pine needle powder, Pericarpium Citri Reticulatae, Semen Glycines, Fructus Cannabis Gan Wenping, regulating qi-flowing for strengthening spleen, nourishing YIN to relieve dryness, altogether for making medicine, ferrous sulfate, copper sulfate, Sal, multidimensional supplement body jointly must nutrient.Therefore, full side demonstrates the effect that effectively can promote poultry spleen benefiting and stimulating the appetite, quick fattening.
Positive beneficial effect of the present invention:
(1) from traditional Chinese veterinary medicine angle analysis, " exogenous pathogen mutual aid " is numerous disease predisposing factors, and when the five internal organs that namely traditional Chinese medical science is said are in " void ", virus is taken advantage of a weak point, and causes pathogen being excessive but vital QI weak, disease-resistant unable; Many because of the damp and hot fire-transformation of diseases caused by exogenous pathogenic factor, cause inhibited pulmonary QI, abnormal ascending-descending of QI, imbalance of YIN and YANG.Chinese herbal medicine can YIN and YANG balance regulating, treating both the principal and secondary aspects of a disease, make body constitutionally, immunity is thought and acted in one and the same way, equilibrium between yin and yang, thus reach the ideal cultivation state of " ill to send out less, morbidity die less ".The present invention's science of being carried out by various Chinese medicine reasonable compatibility is extracted and is used, and plays the complementary action of different mechanism of action, thus plays the effect of stronger antibacterial, antiviral, raising immunity.
(2) adopt microbial fermentation technology, the effective ingredient of medicine is converted into and is easy to absorb and fast onset effect, adopt ultrasonic grinding technology simultaneously, effective ingredient is not destroyed, ensure that effective ingredient is sufficient, drug effect increases.
(3) the present invention has the effect of spleen benefiting and stimulating the appetite, quick fattening, enhances the function of poultry body taste, effectively can strengthen appetite of livestock and poultry, improve food conversion ratio, promote poultry quick fattening, pure Chinese medicine also mitigates the potential safety hazard that chemical medicine causes, and adds the safety of medication.
(4) drug effect plays rapidly, and side effect is little, the time that plays a role short (5 ~ 7 days), easy to use.
Detailed description of the invention
In embodiments of the invention, the concrete preparation method of composite bacteria liquid is as follows: a. respectively extracting lactic acid bacterium, yeast, streptococcus faecalis and bacillus cereus carries out slant strains cultivation respectively as strain, is added to increase in bacterium cultured solution of broth after the bacterium colony normal saline eluting that often kind of slant culture is produced and make suspension, and then amplification culture is distinguished in appropriate media, be cultured to exponential phase 0.5 × 10 8cFU/mL to 1.0 × 10 8during CFU/mL only; B. the lactobacillus suspension, yeast liquid, streptococcus faecalis liquid and the bacillus liquid that are obtained by step a are according to 2:(1-2): 1:1 ratio is mixed to get composite bacteria liquid.
Embodiment 1
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 20-25, Xin Ye 10-12, Semen Phaseoli 8-10, Semen Glycines 8-10, Rhizoma Osmundae 10-12, Fructus Hordei Germinatus 15-20, Herba Gelsemii Elegantis 10-12, Radix Polygoni Multiflori 8-10, Radix Astragali 8-10, Semen Ziziphi Spinosae 8-10, Fructus Ligustri Lucidi 10-12, Pericarpium Citri Reticulatae 20-25, Fructus Schisandrae Chinensis 10-12, Folium Isatidis 20-25, Folium paulowniae 15-20, pine needle powder 20-25, Fructus Cannabis 8-10, ferrous sulfate 5-8, copper sulfate 3-5, Sal 5-8, multidimensional 3-5.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 20-80 object sieve and carries out preliminary treatment;
Step 2, each composition step one handled well mixes, and then to add weight portion be that the composite bacteria liquid of 2-3 mixes, and at the culture medium top fermentation 16-18 hour of 35-37 DEG C, adds stabilizing agent mixing and save backup after being cooled to 20-25 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 20-30%, bean cake 3-4%, ammonium sulfate 1-2%, magnesium sulfate 0.5-1%, calcium carbonate 1-2% and water 20-30%.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.05-0.08% and antioxidant propyl gallate 0.008-0.01%.
In described step 2, extracting lactic acid bacterium, yeast, streptococcus faecalis and bacillus cereus carry out slant strains cultivation as strain to the concrete preparation method of composite bacteria liquid: a. respectively respectively, is added to increase in bacterium cultured solution of broth after the bacterium colony normal saline eluting that often kind of slant culture is produced and make suspension, and then amplification culture is distinguished in appropriate media, be cultured to exponential phase 0.5 × 10 8cFU/mL to 1.0 × 10 8during CFU/mL only; B. the lactobacillus suspension, yeast liquid, streptococcus faecalis liquid and the bacillus liquid that are obtained by step a are according to 2:(1-2): 1:1 ratio is mixed to get composite bacteria liquid.
Embodiment 2
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 20g, Xin Ye 10g, Semen Phaseoli 10g, Semen Glycines 10g, pass through 10 many g, Fructus Hordei Germinatus 20g, Herba Gelsemii Elegantis 10g, Radix Polygoni Multiflori 10g, Radix Astragali 10g, Semen Ziziphi Spinosae 10g, Fructus Ligustri Lucidi 10g, Pericarpium Citri Reticulatae 20g, Fructus Schisandrae Chinensis 10g, Folium Isatidis 20g, Folium paulowniae 20g, pine needle powder 20g, Fructus Cannabis 10g, ferrous sulfate 5g, copper sulfate 5g, Sal 5g, multidimensional 5g.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 20 orders, carry out preliminary treatment after 80 object sieves;
Step 2, each composition step one handled well mixes, and then to add weight portion be that the composite bacteria liquid of 2-3 mixes, and the culture medium top fermentation 18 hours of 35 DEG C, adds stabilizing agent mixing and save backup after being cooled to 25 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 65g, bean cake 8g, ammonium sulfate 5g, magnesium sulfate 3g, calcium carbonate 5g and water 53g.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.3 g and antioxidant propyl gallate 0.04g.
Compound bacteria in described step 2 is compound lactobacillus, yeast, streptococcus faecalis, compound bacillus quality be respectively 1 g, 0.5 g, 0.5 g, 0.5 g.
Embodiment 3
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 25g, Xin Ye 11g, Semen Phaseoli 9g, Semen Glycines 10g, pass through 11 many g, Fructus Hordei Germinatus 18g, Herba Gelsemii Elegantis 8g, Radix Polygoni Multiflori 9g, Radix Astragali 11g, Semen Ziziphi Spinosae 9g, Fructus Ligustri Lucidi 10g, Pericarpium Citri Reticulatae 23g, Fructus Schisandrae Chinensis 10g, Folium Isatidis 24g, Folium paulowniae 18g, pine needle powder 25g, Fructus Cannabis 10g, ferrous sulfate 7g, copper sulfate 4g, Sal 8g, multidimensional 5g.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 80 object sieves and carries out preliminary treatment;
Step 2, each composition step one handled well mixes, and then to add weight be that the composite bacteria liquid of 2g mixes, and the culture medium top fermentation 17 hours of 37 DEG C, adds stabilizing agent mixing and save backup after being cooled to 22 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 72g, bean cake 8g, ammonium sulfate 3g, magnesium sulfate 1g, calcium carbonate 5g and water 53g.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.24 g and antioxidant propyl gallate 0.04g.
Compound bacteria in described step 2 is compound lactobacillus, yeast, streptococcus faecalis, compound bacillus quality be respectively 1g, 0.5g, 0.5 g, 0.5g.
Embodiment 4
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 21g, Xin Ye 12g, Semen Phaseoli 8g, Semen Glycines 9g, pass through 10 many g, Fructus Hordei Germinatus 18g, Herba Gelsemii Elegantis 9g, Radix Polygoni Multiflori 8g, Radix Astragali 15g, Semen Ziziphi Spinosae 8g, Fructus Ligustri Lucidi 11g, Pericarpium Citri Reticulatae 25g, Fructus Schisandrae Chinensis 11g, Folium Isatidis 22g, Folium paulowniae 20g, pine needle powder 23g, Fructus Cannabis 9g, ferrous sulfate 5g, copper sulfate 5g, Sal 7g, multidimensional 5g.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 20 orders, carry out preliminary treatment after 80 object sieves;
Step 2, each composition step one handled well mixes, and then to add weight be that the composite bacteria liquid of 3g mixes, and the culture medium top fermentation 18 hours of 37 DEG C, adds stabilizing agent mixing and save backup after being cooled to 24 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 68g, bean cake 10g, ammonium sulfate 5g, magnesium sulfate 2g, calcium carbonate 3g and water 73g.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.34 g and antioxidant propyl gallate 0.03g.
Compound bacteria in described step 2 is compound lactobacillus, yeast, streptococcus faecalis, compound bacillus quality be respectively 1.2g, 0.9 g, 0.45 g, 0.45 g.
Embodiment 5
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 20g, Xin Ye 11g, Semen Phaseoli 10g, Semen Glycines 8g, pass through 12 many g, Fructus Hordei Germinatus 19g, Herba Gelsemii Elegantis 8g, Radix Polygoni Multiflori 9g, Radix Astragali 10g, Semen Ziziphi Spinosae 10g, Fructus Ligustri Lucidi 12g, Pericarpium Citri Reticulatae 23g, Fructus Schisandrae Chinensis 10g, Folium Isatidis 21g, Folium paulowniae 17g, pine needle powder 25g, Fructus Cannabis 8g, ferrous sulfate 5g, copper sulfate 5g, Sal 6g, multidimensional 3g.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 80 mesh sieves and carries out preliminary treatment;
Step 2, each composition step one handled well mixes, and then to add weight be that the composite bacteria liquid of 2g mixes, and the culture medium top fermentation 16 hours of 36 DEG C, adds stabilizing agent mixing and save backup after being cooled to 25 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 50g, bean cake 8g, ammonium sulfate 3g, magnesium sulfate 3g, calcium carbonate 5g and water 66g.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.19 g and antioxidant propyl gallate 0.04g.
Compound bacteria in described step 2 is compound lactobacillus, yeast, streptococcus faecalis, compound bacillus quality be respectively 1g, 0.4g, 0.3g, 0.3g.
Embodiment 6
For the compound fermentation type Chinese medicine that poultry are fattened, be made up of the material of following weight portion: Fructus Crataegi 24g, Xin Ye 12g, Semen Phaseoli 10g, Semen Glycines 9g, pass through 11 many g, Fructus Hordei Germinatus 15g, Herba Gelsemii Elegantis 10g, Radix Polygoni Multiflori 10g, Radix Astragali 14g, Semen Ziziphi Spinosae 10g, Fructus Ligustri Lucidi 10g, Pericarpium Citri Reticulatae 24g, Fructus Schisandrae Chinensis 10g, Folium Isatidis 25g, Folium paulowniae 20g, pine needle powder 20g, Fructus Cannabis 9g, ferrous sulfate 7g, copper sulfate 3g, Sal 5g, multidimensional 5g.
For a preparation method for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 20 orders, carry out preliminary treatment after 80 object sieves;
Step 2, each composition step one handled well mixes, and then to add weight be that the composite bacteria liquid of 2g mixes, and the culture medium top fermentation 16 hours of 36 DEG C, adds stabilizing agent mixing and save backup after being cooled to 25 DEG C.
The each composition of culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 53g, bean cake 8g, ammonium sulfate 5g, magnesium sulfate 2g, calcium carbonate 3g and water 66g.
Stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.0.24 g and antioxidant propyl gallate 0.04g.
Compound bacteria in described step 2 is compound lactobacillus, yeast, streptococcus faecalis, compound bacillus quality be respectively 1g, 0.4g, 0.3g, 0.3g.
this Chinese herbal medicine proves according to clinical trial
This Chinese herbal medicine through ultrasonic grinding and cell wall wall breaking technology, then carries out micro-ecology fermentation, and direct spice uses.Prove according to 3000 broiler clinical trials, haul oneself willingly into observation post administration, chicken mine massively appetite improve, keep Intestine of Broiler stable acidic environment, make intestinal keep low pH value, suppress harmful intestinal tract bacteria propagation, for probiotics provides nutrition, improves immunity of meat chickens and anti-stress ability, improve feed conversion rate, repair damaged organ fast, improve broiler health, reduce death rate, improve growth of meat chicken performance and economic benefit
2, drug absorption is abundant, and the persistent period that plays a role is long, lasting medicine.
Through comparing: normal Chinese herbal medicine stops 2-6 hour at digestive system, and after this technical finesse, be 8-12 hour in the effective time of birds digestive system, substantially prolongs the time of staying in intestinal, absorption rate significantly increases, and through comparing, common Chinese (40-60 order) can detect a large amount of Chinese medicine prototypes after discharging with feces in intestinal, and this experiment product is after discharging through feces, almost can't check.MIC also obviously differs simultaneously, and this experiment product is higher than common Chinese by 95%.
3, body non-specific immunity strengthens, and body weight significantly increases 19.56%, and feed conversion rate improves 26.31%, and premunition strengthens, and protective rate improves 10.79%.
the model case of Chinese medicine composition clinical efficacy:
The concrete formula that this model case uses and preparation method as described in Example 2, make an addition in feedstuff in the ratio of feedstuff 0.5-1%.
Example one: Jiaozhuo, Henan plant about 3000 0 Japanese instar chicklings, compound fermentation Chinese medicine composition prepared by application the present invention carries out 0.5% feedstuff and adds use 48 days, compared with the same addition of common Chinese preparation, fermented tcm chicken of feeding appetite of mining massively significantly improves, immunity of meat chickens and anti-stress ability are significantly improved, improve the growth regularity of chicken, significantly improve broiler health, reduce death rate, improve meat chicken production performance and economic benefit, improve survivability of chicks, improve the brightness of broiler feather gloss, cockscomb is rubescent, chicken feet jaundice is bright, the feather picking anus pecking that treatment malnutrition causes, accelerate growth of meat chicken, shorten the livestock on hand phase, broiler carcass is plentiful, meat is vivid, deliver 5-8 days in advance for sale.
Example two: 500, Jiyuan, Henan pig farm, applies compound fermentation Chinese medicine composition prepared by the present invention from 21 ages in days, adopts the mode administration of 0.5% spice administration, is used in conjunction to delivering for sale, carries out strict sterilization to pig house and surrounding.Compared with the same addition of common Chinese preparation, daily gain significantly improves 15%-20%.

Claims (5)

1., for the compound fermentation type Chinese medicine that poultry are fattened, it is characterized in that being made up of the material of following weight portion: Fructus Crataegi 20-25, Xin Ye 10-12, Semen Phaseoli 8-10, Semen Glycines 8-10, Rhizoma Osmundae 10-12, Fructus Hordei Germinatus 15-20, Herba Gelsemii Elegantis 10-12, Radix Polygoni Multiflori 8-10, Radix Astragali 8-10, Semen Ziziphi Spinosae 8-10, Fructus Ligustri Lucidi 10-12, Pericarpium Citri Reticulatae 20-25, Fructus Schisandrae Chinensis 10-12, Folium Isatidis 20-25, Folium paulowniae 15-20, pine needle powder 20-25, Fructus Cannabis 8-10, ferrous sulfate 5-8, copper sulfate 3-5, Sal 5-8, multidimensional 3-5.
2. the preparation method of the compound fermentation type Chinese medicine of fattening for poultry as claimed in claim 1, is characterized in that comprising the steps:
Step one, takes by weight by each for Chinese medicine composition, adopts ultrasonic grinding to pulverize respectively, then crosses 20-80 object sieve and carries out preliminary treatment;
Step 2, each composition step one handled well mixes, and then to add weight portion be that the composite bacteria liquid of 2-3 mixes, and at the culture medium top fermentation 16-18 hour of 35-37 DEG C, adds stabilizing agent mixing and save backup after being cooled to 20-25 DEG C.
3. the preparation method of compound fermentation type Chinese medicine of fattening for poultry according to claim 2, it is characterized in that, each composition of the culture medium in described step 2 is the mass percent of each composition sum of Chinese medicine: wheat bran 20-30%, bean cake 3-4%, ammonium sulfate 1-2%, magnesium sulfate 0.5-1%, calcium carbonate 1-2% and water 20-30%.
4. the preparation method of compound fermentation type Chinese medicine of fattening for poultry according to claim 2, it is characterized in that, the stabilizing agent in described step 2 is the mass percent of each composition sum of Chinese medicine: preservative sodium benzoate 0.05-0.08% and antioxidant propyl gallate 0.008-0.01%.
5. the preparation method of compound fermentation type Chinese medicine of fattening for poultry according to claim 2, it is characterized in that, in described step 2, extracting lactic acid bacterium, yeast, streptococcus faecalis and bacillus cereus carry out slant strains cultivation as strain to the concrete preparation method of composite bacteria liquid: a. respectively respectively, is added to increase in bacterium cultured solution of broth after the bacterium colony normal saline eluting that often kind of slant culture is produced and make suspension, and then amplification culture is distinguished in appropriate media, be cultured to exponential phase 0.5 × 10 8cFU/mL to 1.0 × 10 8during CFU/mL only; B. the lactobacillus suspension, yeast liquid, streptococcus faecalis liquid and the bacillus liquid that are obtained by step a are according to 2:(1-2): 1:1 ratio is mixed to get composite bacteria liquid.
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