CN103948699A - Traditional Chinese medicinal formula for treating migraine - Google Patents
Traditional Chinese medicinal formula for treating migraine Download PDFInfo
- Publication number
- CN103948699A CN103948699A CN201410159352.1A CN201410159352A CN103948699A CN 103948699 A CN103948699 A CN 103948699A CN 201410159352 A CN201410159352 A CN 201410159352A CN 103948699 A CN103948699 A CN 103948699A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- traditional chinese
- chinese medicinal
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a traditional Chinese medicinal formula for treating migraine. The traditional Chinese medicament is prepared from the following raw materials in parts by weight: 20-40 parts of ligusticum wallichii, 15-20 parts of notopterygium root, 14-20 parts of angelica root, 15-20 parts of divaricate saposhnikovia root, 15-20 parts of silkworm larva, 10-15 parts of mint, 5-10 parts of coptis chinensis, 5-10 parts of scutellaria baicalensis, 20-30 parts of radix achyranthis bidentatae and 5-10 parts of cinnamon. The traditional Chinese medicinal formula can be used for effectively eliminating all clinical symptoms of migraine, is remarkable in clinical curative effect, hardly has toxic or side effects, can remarkably improve symptoms of a patient and relieve pains, and has higher popularization and application values; practice on 500 clinical cases proves that the total effective rate of the traditional Chinese medicinal formula is over 95 percent; all adopted raw materials are common traditional Chinese medicinal materials and are low in price and easily available, the treatment method is simple and convenient, and the administration compliance is good.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate generally to one and treat migrainous Chinese medicine formula.
Background technology
Migraine claims again vascular headache, nervous headache; it is a kind of headache of repeatability outbreak; it is clinical common primary headache; it is characterized in that ictal, mostly be inclined to one side side, middle severe, the sample of beating headache; general 4～72 h that continue; can be with feeling sick, vomitting, light, sound stimulate or daily routines all can increase the weight of headache, and quiet environment, rest can be alleviated headache.Migraine belongs to clinical common chronic neural blood vessel disorder disease, and it can betide any age bracket, is more common between 35-45 year and peaks, and incidence rate afterwards declines with advancing age and gradually.Its sickness rate is higher, and serious harm people's is healthy.Showing according to the study, more easily there is brain local damage in migraine patient than usual people, and the attack times of its migraine is more, and the region of brain damaged can be larger.Migraine is common clinical and frequently-occurring disease, is nerve, dysfunction of blood vessel disease that the side of repeatedly showing effect or bilatenal headache are feature, has a strong impact on people's daily studying and living.
Still not fully aware of to migrainous pathogeny and pathological molecule mechanism at present.Generally adopt clinically aspirin, indometacin, Thebe woods, piracetam etc. to treat, but Western medicine can only be alleviated slight illness, cannot effect a radical cure the state of an illness, effective percentage, for lower, is prone to drug resistance, and side effect is larger.Therefore, clinical effectiveness is not remarkable.So exploitation is a kind of, and effectively medicine is significant.
Summary of the invention
In order to address the above problem, the invention provides one and can effectively eliminate migrainous all clinical symptoms, clinical efficacy is remarkable, the Chinese medicine formula of almost non-toxic side effect.
The object of the present invention is to provide one to treat migrainous Chinese medicine formula.
The technical solution used in the present invention is:
One is treated migrainous Chinese medicine formula, and its raw material by following parts by weight forms: Rhizoma Chuanxiong 20-40 part, Rhizoma Et Radix Notopterygii 15-20 part, Radix Angelicae Dahuricae 15-20 part, Radix Saposhnikoviae 15-20 part, Bombyx Batryticatus 15-20 part, Herba Menthae 10-15 part, Rhizoma Coptidis 5-10 part, Radix Scutellariae 5-10 part, Radix Achyranthis Bidentatae 20-30 part, Cortex Cinnamomi 5-10 part.
Further, one is treated migrainous Chinese medicine formula, and its raw material by following parts by weight forms: 30 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Saposhnikoviaes, 15 parts of Bombyx Batryticatus, 15 parts of Herba Menthaes, 6 parts of Rhizoma Coptidis, 6 parts of Radix Scutellariaes, 20 parts of Radix Achyranthis Bidentataes, 6 parts of Cortex Cinnamomis.
The invention has the beneficial effects as follows:
1) Chinese medicine formula of the present invention can effectively be eliminated migrainous all clinical symptoms, and clinical efficacy is remarkable, and almost non-toxic side effect significantly improves patient's symptom, eases the pain, and has higher application value.
2) experimentation of the present invention confirms, Chinese medicine formula of the present invention can be adjusted orthosympathetic function, make vasomotoricity recover normal, remove in time the spasticity of blood vessel, make local organization blood supply recover normal, microcirculation improving action, thus bring into play good analgesia, sedation, migraine is had to significant clinical efficacy.Through the practice of clinical 500 examples, total effective rate reaches more than 95%.
3) raw material that the present invention adopts is common Chinese medicinal material, and cheap and easy to get, Therapeutic Method is easy, and medication compliance is good.
Detailed description of the invention
a kind of preparation for the treatment of migrainous Chinese medicine formula
1) take respectively the raw material of Chinese medicine of following parts by weight: Rhizoma Chuanxiong 20-40 part, Rhizoma Et Radix Notopterygii 15-20 part, Radix Angelicae Dahuricae 15-20 part, Radix Saposhnikoviae 15-20 part, Bombyx Batryticatus 15-20 part, Herba Menthae 10-15 part, Rhizoma Coptidis 5-10 part, Radix Scutellariae 5-10 part, Radix Achyranthis Bidentatae 20-30 part, Cortex Cinnamomi 5-10 part.
2), then according to regular pharmaceutical technology flow process, be produced into clinical conventional various pharmaceutical dosage forms, as concentrated granular electuary, Chinese medicine oral liquid, tablet or capsule.
Preferably, the parts by weight of each raw material of Chinese medicine are: 30 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Saposhnikoviaes, 15 parts of Bombyx Batryticatus, 15 parts of Herba Menthaes, 6 parts of Rhizoma Coptidis, 6 parts of Radix Scutellariaes, 20 parts of Radix Achyranthis Bidentataes, 6 parts of Cortex Cinnamomis.
The present invention is the migrainous Chinese medicine composition for the treatment of, and its TCM Recipe solution is as follows:
Rhizoma Chuanxiong: property and flavor of peppery and warm, return liver, the heart, gallbladder three warps, function: blood-activating and qi-promoting, loose wind pain relieving, cures mainly stagnation of QI due to depression of the liver, costa sternales pain, migraine and general headache, general pain, rheumatic Bi syndrome.For " all key medicines through headache ", be good at expelling wind and activating blood circulation and only headache, and be longer than the few sun for the treatment of, JUE YIN meridian headache.
Rhizoma Et Radix Notopterygii: arduous and warm, return bladder, kidney channel.Effect: cold expelling, dispel the wind, dehumidifying, pain relieving.Cure mainly cold, have a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, the diseases such as skin sore.Be longer than the headache for the treatment of Taiyang channel.
The Radix Angelicae Dahuricae: pungent, warm, return stomach, large intestine, lung meridian.Effect: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.Cure mainly flu, headache, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Be longer than the headache for the treatment of Yangming Channel.
Radix Saposhnikoviae: acrid, sweet, warm, return bladder, liver, spleen channel.Function: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.Cure mainly headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.Anti-wind energy " all ailment said due to cold or exposure of extensively treating ", for controlling the key medicine of wind pain relieving.With to declare loose Head And Face ailment said due to cold or exposure.
Bombyx Batryticatus: acrid in the mouth, salty, property is flat, returns liver, lung, stomach warp.Function: expelling wind and relieving convulsion; Dissipating phlegm and resolving masses; Resolving toxin and disinhibiting the throat.Curing mainly frightened epilepsy twitches; Middle air port eye is oblique; Migraine and general headache; Abscess of throat; Scrofula; Mumps; Rubella; The illnesss such as sore.
Herba Menthae: pungent, cool, return lung, Liver Channel.Function: dispelling wind-heat, the clear sharp head, rash.Cure mainly anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast side of body feeling of distension and oppression.
Rhizoma Coptidis: hardship, cold, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.With one of the clear part of the body cavity above the diaphragm housing the heart and lungs burning hot.
Radix Scutellariae: hardship, cold, return lung, gallbladder, spleen, large intestine, small intestine meridian.Function: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Cure mainly hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Radix Achyranthis Bidentatae: bitter, sour, flat, return liver, kidney channel.Function: invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.Cure mainly soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.Radix Achyranthis Bidentatae " walk and can mend, property is kind descending ", the facial wind-fire of leader used is descending and separate.
Cortex Cinnamomi: pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel.Function: mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Cure mainly sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
In this Chinese medicine composition, Rhizoma Chuanxiong, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae three medicines share, the ailment said due to cold or exposure of the few sun of the loose Head And Face of a surname, the sun, Yangming Channel and pain relieving is monarch drug altogether; Radix Saposhnikoviae, Bombyx Batryticatus, Herba Menthae, auxiliary monarch drug is strengthened the loose ailment said due to cold or exposure of a surname, the clear sharp head and pain relieving is ministerial drug altogether; Rhizoma Coptidis, Radix Scutellariae removing summer-heat part of the body cavity above the diaphragm housing the heart and lungs pathogenic heat are assistant; Radix Achyranthis Bidentatae draws the descending double invigorating the liver and kidney of invigorating blood circulation of heat, and Cortex Cinnamomi guiding fire to origin, altogether for making medicine.All medicines share, the loose Head And Face ailment said due to cold or exposure of a surname, and the clear sharp head and pain relieving, play effect of dispelling wind and relieving jointly.
Experimentation of the present invention confirms, it can adjust orthosympathetic function, make vasomotoricity recover normal, remove in time the spasticity of blood vessel, make local organization blood supply recover normal, microcirculation improving action, thus bring into play good analgesia, sedation, migraine is had to significant clinical efficacy.Through the practice of clinical 500 examples, total effective rate reaches more than 95%.
Below in conjunction with specific embodiment to the present invention do under explanation, but be not limited to this.
embodiment 1: one is treated migrainous Chinese medicine formula
Take respectively the raw material of Chinese medicine of following parts by weight: 30 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Saposhnikoviaes, 15 parts of Bombyx Batryticatus, 15 parts of Herba Menthaes, 6 parts of Rhizoma Coptidis, 6 parts of Radix Scutellariaes, 20 parts of Radix Achyranthis Bidentataes, 6 parts of Cortex Cinnamomis.
Preparation method: to the strict selection of the former material of Chinese medicine, cleaning, drying, then according to regular pharmaceutical technology flow process, are produced into clinical conventional various pharmaceutical dosage forms, as concentrated granular electuary, Chinese medicine oral liquid, tablet or capsule.
Instructions of taking: make after fixed dosage form, according to dosage difference, oral, every day 2 times or 3 times, within 30 days, be a course for the treatment of.
embodiment 2: one is treated migrainous Chinese medicine formula
Take respectively the raw material of Chinese medicine of following parts by weight: 20 parts of Rhizoma Chuanxiongs, 15 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Saposhnikoviaes, 20 parts of Bombyx Batryticatus, 15 parts of Herba Menthaes, 5 parts of Rhizoma Coptidis, 10 parts of Radix Scutellariaes, 20 parts of Radix Achyranthis Bidentataes, 5 parts of Cortex Cinnamomis.
Preparation method: to the strict selection of the former material of Chinese medicine, cleaning, drying, then according to regular pharmaceutical technology flow process, are produced into clinical conventional various pharmaceutical dosage forms, as concentrated granular electuary, Chinese medicine oral liquid, tablet or capsule.
Instructions of taking: make after fixed dosage form, according to dosage difference, oral, every day 2 times or 3 times, within 30 days, be a course for the treatment of.
embodiment 3: one is treated migrainous Chinese medicine formula
Take respectively the raw material of Chinese medicine of following parts by weight: 40 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Et Radix Notopterygiis, 15 parts of the Radixs Angelicae Dahuricae, 15 parts of Radix Saposhnikoviaes, 15 parts of Bombyx Batryticatus, 10 parts of Herba Menthaes, 10 parts of Rhizoma Coptidis, 10 parts of Radix Scutellariaes, 30 parts of Radix Achyranthis Bidentataes, 10 parts of Cortex Cinnamomis.
Preparation method: to the strict selection of the former material of Chinese medicine, cleaning, drying, then according to regular pharmaceutical technology flow process, are produced into clinical conventional various pharmaceutical dosage forms, as concentrated granular electuary, Chinese medicine oral liquid, tablet or capsule.
Instructions of taking: make after fixed dosage form, according to dosage difference, oral, every day 2 times or 3 times, within 30 days, be a course for the treatment of.
The migrainous Chinese medicine formula for the treatment of of the present invention is made to further effect detection below.
1 clinical data
1.1 physical data
Select medical migraineur's 360 examples of in December, 2009～2013 year December Jian Wo institute, case selection meets Migraine without aura in the international headache migrainous classification of association in 2004 and diagnosis and has the migrainous diagnostic criteria of tendency type: 1. meet 2.～at least 5 outbreaks 4.; 2. headache outbreak (untreated or fail to respond to any medical treatment) continues 4～72 hours; 3. have 2 headache feature (one-sided property in following at least; Pulsation; In or severe pain; When increasing the weight of headache or headache, daily routines meeting avoids sort of activity); 4. in headache process, at least follow following l item (n or V; Photophobia and phonophobia; Can not be owing to Other diseases).
Inclusive criteria: meet above-mentioned Western medicine diagnose standard, and to meet tcm diagnosis be wind syndrome of head patient, the age between 18～68 years old, be ready partner treatment operation, check and efficacy evaluation person.
Exclusion standard: the headache due to organic disease, cervical spondylosis, the infectious disease such as hypertension, cerebrovascular accident, the cerebral tumor, except anemia of pregnant woman, the person that goes out coagulation disorders.
Standard comes off: include in and divide into groups, but because a variety of causes does not complete this treatment observer in accordance with regulations, as treatment group does not complete course of therapy person, that observation of curative effect records is imperfect, cannot judge curative effect person, not drug administration person on request for the treatment of of control group.
Selected patient is divided into two groups at random, every group of 180 example, wherein treatment group: male's 83 examples, women's 97 examples, 19～65 years old age, average (36.93 ± 8.42) year; Matched group: male's 81 examples, women's 89 examples, 22～67 years old age, average (34.50 ± 9.17) year.Two groups of physical data comparisons, the equal not statistically significant of difference (p > 0.05), has comparability.
1.2 Therapeutic Method
Matched group gives general treatment, oral hydrochloride flunarizine capsule (Tianjin Pharmaceutical Group Xinzheng Co., Ltd., lot number: H20067316), and 5mg/d, once a day, takes 4 weeks continuously.Treatment group is selected the migrainous Chinese medicine formula of the treatment described in embodiment 1, and 1 dose of every day (every dose of 158g), decocting 2 times boils 35min at every turn, the about 600ml of extracting juice altogether, and each decoction being taken warmly 300ml, takes 4 weeks continuously sooner or later.
1.3 criterion of therapeutical effect
Draft criterion of therapeutical effect with reference to Ministry of Health of the People's Republic of China's " new Chinese medicine guideline of clinical investigations " and " neurological ".Clinical recovery: headache and simultaneous phenomenon disappear; Effective: pain intensity and simultaneous phenomenon obviously alleviate, attack times reduces, and the persistent period reduces more than 2/3; Effective: headache alleviates to some extent, outbreak extends interval time, and the persistent period reduces more than 1/3; Invalid: pain is without obvious variation or increase the weight of, attack times increases, and the persistent period is extended for.
Headache degree standard: adopt visual analogue scales (VAS) scoring, 0～10 point of scale.No headache: be 0 point; Slight headache: headache does not affect daily routines (1≤mark < 4); Moderate headache: headache affects daily routines, working and learning (4≤mark < 7); Severe headache: because headache must bed cause working or to learn (7≤mark < 10).
1.4 statistical procedures
Adopt SPSS16.0 software to carry out data statistic analysis, measurement data data represent with " X ± s ", relatively adopt t inspection between group; Between enumeration data group, relatively adopt X
2inspection, has statistical significance taking P<0.05 as difference.
2 interpretations of result
2.1 clinical and experimental study
1) clinical observation on the therapeutic effect
According to above-mentioned Therapeutic Method, and detect the therapeutic effect of each group, as shown in table 1 below, the effective percentage for the treatment of group is 93.33%, and the effective percentage of matched group is 68.89%, and result proves, Chinese medicine coordinates acupuncture treatment group total effective rate apparently higher than matched group, and difference has statistical significance.
Table 1 treatment group and matched group Clinical efficacy comparison
Note: * represents and relatively p < 0.05 of matched group
2) VAS scoring
Above-mentioned therapeutic effect is carried out to VAS headache scoring, as shown in table 2, the treatment group before treatment and the VAS of matched group scoring and attack times there was no significant difference (P > 0.05); After treatment, VAS scoring and the attack times of matched group and treatment group all decrease before treating, but the improvement for the treatment of group is obviously better than matched group (P < 0.05).
vAS scoring and the comparison of morbidity number of times before and after table 2 liang group treatment
Note: * represents and treatment group is treated front relatively p < 0.05,
#represent and the front relatively p < 0.05 for the treatment of of control group.
3) conclusion
Migraine is a kind of stubborn disease taking head outbreak pain as main manifestations being caused by vasomotor dysfunction.Migraine belongs to the traditional Chinese medical science " wind syndrome of head ", " headache caused by pathogenic wind " category.Chinese medicine thinks, head is " confluence of all yang-channels " " the house of mind " brain being the marrow sea ".The gas of the blood of the five internal organs elite, the clear sun of six internal organs, all can be in head, normal circulation of qi and blood, and spirit and QI cleaning of the clear spirit of brain, therefore generation and internal organs, the QI and blood of having a headache, expectorant is turbid, blood stasis is closely related.Evil resistance venation, clear key is unfavorable, is the basic pathogenesis of migraine.Modern medicine thinks that the many factors such as the morbidity of this disease and inherited genetic factors, vascular factor, hemorheology and mediator class factor, endocrine factors, physical factor, neural Nervous and Mental Factors have.About its pathogenesis, think due to dysfunction of blood vessel and the change of body biochemical substances more.
In the formula of above-described embodiment, Rhizoma Chuanxiong can blood circulation promoting and blood stasis dispelling, again can dissipating depression of QI pain relieving, and the descending sea of blood, the up head, its speciality clear light gas of body that can induce one is up in brain, for controlling the key medicine of headache; The Bombyx Batryticatus wind in network of dispelling; Light clear rising of Herba Menthae, adjusts and reaches stagnation of liver-QI, unclogs and readjusts the stagnation of QI, and play altogether dispelling wind and removing obstruction in the collateral pain relieving, improve the merit of brain microcirculation full side.Study and also show, acupuncture can be adjusted sympathetic nerve, makes cerebral vessels systolic and diastolic function recover normal, and local organization microcirculation is improved, and removes the spasticity of blood vessel, thereby plays dredging the meridian, the effect of wind-expelling pain-stopping.According to above-mentioned therapeutic outcome, the treatment migraine Chinese medicine that uses the present invention to prepare, the clinically good effect of normal acquisition.
In sum, the migrainous Chinese medicine formula for the treatment of of the present invention, can obviously improve clinical efficacy, improves patient's symptom, eases the pain, and has higher application value.
2.2 animal experiment study
Detect in above-described embodiment and treat the impact of migrainous Chinese medicine formula on Nerve in Migraine Model rat cerebral tissue 5-hydroxy tryptamine (5-HT), nitric oxide (NO) and plasma 5-hydroxytryptamine in patients (5-HT), norepinephrine (NE), Endothelin (ET) level.Observe the therapeutical effect of Chinese medicine formula of the present invention to experimental migraine rat model, inquire into its possible treatment mechanism.
1) method
Experimental rat is divided into totally 6 groups of Normal groups, Nerve in Migraine Model group, Flunarizine Hydrochloride for treating group, the high, medium and low dosage treatment group of Chinese medicine formula of the present invention.Respectively with Chinese medicine formula of the present invention 0.40,0.80,1.60g/kg gavage 7 days, observe treatment after each group rat behavior change.Detect respectively the NO of Ge Zu rat cerebral tissue and 5-HT level by immunohistochemical method; Euzymelinked immunosorbent assay (ELISA) is measured plasma 5-hydroxytryptamine in patients (5-HT), norepinephrine (NE), Endothelin (ET) level.
2) result
Nerve in Migraine Model group rat occurs that ear is red, scratches one's head, climbs the phenomenons such as cage, and these phenomenons appear in treatment group hardly that take Chinese medicine formula of the present invention 0.40,0.80,1.60g/kg.With the comparison of blank group, blood plasma 5-HT, NE, the ET content of Nerve in Migraine Model rat significantly raises due to nitroglycerin, and cerebral tissue NO level all raises, and in cerebral tissue, 5-HT content significantly reduces.With model group comparison, the treatment group of taking Chinese medicine formula of the present invention 0.40,0.80,1.60g/kg all can make rat plasma 5-HT, NE, ET content reduce, and in cerebral tissue, 5-HT content raises, and cerebral tissue NO level all reduces, and all has statistical significance.
3) conclusion
The above results illustrate the migrainous medicine composition for the treatment of of the present invention have the rat 5-HT of adjusting, NE, ET, etc. monoamine transmitters and vaso-active substance content, improving cerebral tissue blood supplies, the effectively effect of conditioning vasomotion disorder, this may be that it treats one of migrainous mechanism of action.
Claims (2)
1. the migrainous Chinese medicine formula for the treatment of, it is characterized in that: its raw material by following parts by weight forms: Rhizoma Chuanxiong 20-40 part, Rhizoma Et Radix Notopterygii 15-20 part, Radix Angelicae Dahuricae 15-20 part, Radix Saposhnikoviae 15-20 part, Bombyx Batryticatus 15-20 part, Herba Menthae 10-15 part, Rhizoma Coptidis 5-10 part, Radix Scutellariae 5-10 part, Radix Achyranthis Bidentatae 20-30 part, Cortex Cinnamomi 5-10 part.
2. one according to claim 1 is treated migrainous Chinese medicine formula, it is characterized in that: its raw material by following parts by weight forms: 30 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 20 parts of Radix Saposhnikoviaes, 15 parts of Bombyx Batryticatus, 15 parts of Herba Menthaes, 6 parts of Rhizoma Coptidis, 6 parts of Radix Scutellariaes, 20 parts of Radix Achyranthis Bidentataes, 6 parts of Cortex Cinnamomis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410159352.1A CN103948699B (en) | 2014-04-21 | 2014-04-21 | One treats migrainous Chinese medicine composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410159352.1A CN103948699B (en) | 2014-04-21 | 2014-04-21 | One treats migrainous Chinese medicine composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103948699A true CN103948699A (en) | 2014-07-30 |
| CN103948699B CN103948699B (en) | 2016-02-10 |
Family
ID=51326141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410159352.1A Expired - Fee Related CN103948699B (en) | 2014-04-21 | 2014-04-21 | One treats migrainous Chinese medicine composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103948699B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560618A (en) * | 2015-09-09 | 2016-05-11 | 张苗 | Traditional Chinese medicine for treating cephalic wind syndrome |
| CN106857924A (en) * | 2016-12-22 | 2017-06-20 | 广州肇基生物科技有限公司 | A kind of herbal tea for controlling antimigraine and preparation method thereof |
| CN108143928A (en) * | 2017-12-29 | 2018-06-12 | 刘建民 | A kind of Chinese medicine for treating migraine |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1365749A (en) * | 2001-01-19 | 2002-08-28 | 杨孟君 | Nano medicine 'Xiongju Shangqing' and its preparing process |
| CN1706460A (en) * | 2005-05-14 | 2005-12-14 | 许志炎 | Headache treating Chinese medicine and its prepn process |
-
2014
- 2014-04-21 CN CN201410159352.1A patent/CN103948699B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1365749A (en) * | 2001-01-19 | 2002-08-28 | 杨孟君 | Nano medicine 'Xiongju Shangqing' and its preparing process |
| CN1706460A (en) * | 2005-05-14 | 2005-12-14 | 许志炎 | Headache treating Chinese medicine and its prepn process |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105560618A (en) * | 2015-09-09 | 2016-05-11 | 张苗 | Traditional Chinese medicine for treating cephalic wind syndrome |
| CN106857924A (en) * | 2016-12-22 | 2017-06-20 | 广州肇基生物科技有限公司 | A kind of herbal tea for controlling antimigraine and preparation method thereof |
| CN108143928A (en) * | 2017-12-29 | 2018-06-12 | 刘建民 | A kind of Chinese medicine for treating migraine |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103948699B (en) | 2016-02-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103948699B (en) | One treats migrainous Chinese medicine composition | |
| CN104524247B (en) | One treats migrainous medical composition and its use | |
| CN105535495A (en) | Chinese medicinal composition for treating esophageal cancer by reinforcing vital essence and strengthening primordial qi and preparation method | |
| CN102579750B (en) | Traditional Chinese medicine composition for treating primary dysmenorrhea | |
| CN102091246B (en) | Chinese medicine composition for treating myocardial infarction | |
| CN1915400A (en) | Medication for treating symptoms of the illness of nasosinusitis | |
| CN104225569A (en) | Chinese medicinal composition for treating chronic enteritis | |
| CN103263645B (en) | Gastritis and gastric ulcer treatment drug | |
| CN103272181B (en) | Traditional Chinese medicinal composition for treating qi depression cold-phlegm syndrome globus hystericus | |
| CN105194588A (en) | Traditional Chinese medicine preparation for treating liver cirrhosis | |
| CN105998903A (en) | Traditional Chinese medicine pills for treating gingival pain and swelling | |
| CN101700279A (en) | Traditional Chinese medicine for treating children asthmatic brouchitis | |
| CN105288171A (en) | Pharmaceutical composition for treating male climacteric syndrome | |
| CN108465004A (en) | A kind of Chinese medicine composition for treating migraine | |
| CN104258223A (en) | Traditional Chinese medicine for treating pulmonary tuberculosis | |
| CN102688458B (en) | Chinese medicament for treating primary dysmenorrhea | |
| CN104083733A (en) | Traditional Chinese medicine preparation for cold-type children's bronchitis | |
| CN104257972A (en) | Traditional Chinese medicine for treating child asthmatic pneumonia | |
| CN103432394B (en) | A kind of Chinese medicine treating systemic sclerosis | |
| CN104258361A (en) | Traditional Chinese medicine composition for treating infantile asthma | |
| CN103768464A (en) | Traditional Chinese medicinal composition for treating myelodysplastic syndrome | |
| CN103446370B (en) | Traditional Chinese medicine composition for treating spleen-deficiency and phlegm-turbid stagnation type acne | |
| CN103251841A (en) | Chinese medicinal composition for treating qi-depression phlegm-heat imagined bolus in throat | |
| CN103536894A (en) | Traditional Chinese medicinal composition for treating primary dysmenorrhea | |
| CN105079711A (en) | Traditional Chinese medicine preparation for treating cervical spondylosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160210 Termination date: 20210421 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |