CN104271129A - 使用极光激酶抑制剂治疗癌症的方法 - Google Patents

使用极光激酶抑制剂治疗癌症的方法 Download PDF

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Publication number
CN104271129A
CN104271129A CN201380015806.1A CN201380015806A CN104271129A CN 104271129 A CN104271129 A CN 104271129A CN 201380015806 A CN201380015806 A CN 201380015806A CN 104271129 A CN104271129 A CN 104271129A
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CN
China
Prior art keywords
cancer
administration
purposes according
paclitaxel
lisai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380015806.1A
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English (en)
Chinese (zh)
Inventor
阿里吉特·查克拉瓦蒂
杰弗里·A·埃切迪
罗伯特·W·克莱因菲尔德
卡·N·莱
文·希·徐
卡尔蒂克·文卡塔克里希南
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Millennium Pharmaceuticals Inc
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Millennium Pharmaceuticals Inc
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Filing date
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Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of CN104271129A publication Critical patent/CN104271129A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201380015806.1A 2012-03-20 2013-03-19 使用极光激酶抑制剂治疗癌症的方法 Pending CN104271129A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261613258P 2012-03-20 2012-03-20
US61/613,258 2012-03-20
PCT/US2013/032962 WO2013142491A1 (en) 2012-03-20 2013-03-19 Methods of treating cancer using aurora kinase inhibitors

Publications (1)

Publication Number Publication Date
CN104271129A true CN104271129A (zh) 2015-01-07

Family

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Family Applications (1)

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CN201380015806.1A Pending CN104271129A (zh) 2012-03-20 2013-03-19 使用极光激酶抑制剂治疗癌症的方法

Country Status (24)

Country Link
US (2) US20130303519A1 (enExample)
EP (1) EP2827855B1 (enExample)
JP (1) JP6373252B2 (enExample)
KR (1) KR102128866B1 (enExample)
CN (1) CN104271129A (enExample)
AU (1) AU2013235275B2 (enExample)
CA (1) CA2868024A1 (enExample)
EA (1) EA036434B1 (enExample)
ES (1) ES2746946T3 (enExample)
GE (2) GEAP201813599A (enExample)
IL (1) IL234686B (enExample)
IN (1) IN2014DN08477A (enExample)
JO (1) JO3630B1 (enExample)
MA (1) MA37438A1 (enExample)
MX (1) MX358411B (enExample)
MY (1) MY175225A (enExample)
NZ (1) NZ700744A (enExample)
PH (1) PH12014502109A1 (enExample)
SG (2) SG11201405621UA (enExample)
TN (1) TN2014000387A1 (enExample)
TW (1) TWI649082B (enExample)
UA (1) UA117455C2 (enExample)
WO (1) WO2013142491A1 (enExample)
ZA (1) ZA201407551B (enExample)

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Publication number Priority date Publication date Assignee Title
US20130303519A1 (en) 2012-03-20 2013-11-14 Millennium Pharmaceuticals, Inc. Methods of treating cancer using aurora kinase inhibitors
JP2018502089A (ja) * 2014-12-23 2018-01-25 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． Ｒａｆ阻害剤及びａｕｒｏｒａキナーゼ阻害剤の組み合わせ
JP6786530B2 (ja) * 2015-07-02 2020-11-18 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． オーロラａキナーゼの選択的インヒビターに対する応答のバイオマーカー
CN114681455A (zh) * 2018-08-17 2022-07-01 深圳微芯生物科技股份有限公司 组蛋白去乙酰化酶抑制剂与蛋白激酶抑制剂之组合及其制药用途

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GEAP201813599A (en) 2018-06-25
SG10201607741RA (en) 2016-11-29
IL234686B (en) 2020-01-30
JO3630B1 (ar) 2020-08-27
HK1206253A1 (en) 2016-01-08
KR20140144215A (ko) 2014-12-18
MX358411B (es) 2018-08-20
EP2827855A1 (en) 2015-01-28
US20130303519A1 (en) 2013-11-14
TN2014000387A1 (en) 2015-12-21
MY175225A (en) 2020-06-16
US10213436B2 (en) 2019-02-26
TW201343169A (zh) 2013-11-01
ES2746946T3 (es) 2020-03-09
UA117455C2 (uk) 2018-08-10
KR102128866B1 (ko) 2020-07-01
EA036434B1 (ru) 2020-11-10
EA201491727A1 (ru) 2015-01-30
MA37438A1 (fr) 2016-05-31
PH12014502109A1 (en) 2014-12-10
ZA201407551B (en) 2019-01-30
JP2015510945A (ja) 2015-04-13
NZ700744A (en) 2016-09-30
SG11201405621UA (en) 2014-10-30
MX2014011324A (es) 2014-12-05
US20160193224A1 (en) 2016-07-07
WO2013142491A1 (en) 2013-09-26
IN2014DN08477A (enExample) 2015-05-08
IL234686A0 (en) 2014-11-30
EP2827855B1 (en) 2019-06-26
JP6373252B2 (ja) 2018-08-15
GEP20186900B (en) 2018-10-10
AU2013235275A1 (en) 2014-10-23
AU2013235275B2 (en) 2017-12-07
TWI649082B (zh) 2019-02-01
CA2868024A1 (en) 2013-09-26

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Application publication date: 20150107