CN104189811A - Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof Download PDFInfo
- Publication number
- CN104189811A CN104189811A CN201410408842.0A CN201410408842A CN104189811A CN 104189811 A CN104189811 A CN 104189811A CN 201410408842 A CN201410408842 A CN 201410408842A CN 104189811 A CN104189811 A CN 104189811A
- Authority
- CN
- China
- Prior art keywords
- radix
- chinese medicine
- component
- medicine composition
- minutes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition for treating postpartum fainting. The traditional Chinese medicine composition consists of the following components in parts by weight: herba leonuri, fresh ginger, red jujubes, Chinese ginseng, astragalus, white atractylodes rhizome, Chinese angelica, safflower, fructus lycii, radix paeoniae rubra, donkey-hide gelatin, ligusticum wallichii, radix curcumae, liquorice, lotus leaf, herba ecliptae, benzoin, polygonum multiflorum, peach kernels, prepared rehmannia root and rhizoma cyperi. The traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, tonifying qi, regulating flow of qi and relieving pains, increasing uterine contraction amplitude, reducing postpartum hemorrhage, strengthening immunity of the body and improving the hematopoietic function of the body. The traditional Chinese medicine composition adopts a pure traditional Chinese medicine preparation, is safe and free of pollution, free of toxic and side effects, reasonable in formula, remarkable in curative effect, and free of adverse reaction, as well as toxic and side effects.
Description
Technical field
The invention belongs to Chinese materia medica technical field, be specifically related to a kind of Chinese medicine composition for the treatment of puerperal blood faints and preparation method thereof.
Background technology
Puerperal blood faints is one of obstetrics' common disease.Main manifestations is to have a dizzy spell suddenly after parturient childbirth, can not play seat, or ambition is full vexed, nausea and vomiting, and what is said or talked about is gushed out of breath, vexed uneasiness, even coma locked mouth, syncope, claims again " blood fortune in puerperal ".
Primary disease is equivalent to collapse, the shock that western medicine postpartum hemorrhage causes, pregnancy associated with cardiac disease heart failure in puerperal, or the disease such as amniotic embolism are one of severe crisis in puerperal, if treatment not in time, often jeopardize puerpera's life, or becomes raw his disease because asthenia of qi and blood declines.
The main not outer deficiency and excess of pathogenesis two ends, cloudy blood is died cruelly, lack of preservation of spirit, or blood stasis stagnation, QI rising in reverse order is made a psychological attack.Be divided into two kinds:
One, blood deficiency QI prostration
The first deficiency of vital energy of new product is exhausted, or because of childbirth trauma uterus, blood goes too much, under battalion's the moon, takes by force, excessive bleeding associated with exhaustion of QI, and lack of preservation of spirit, causes and makes bruise.
Two, blood stasis leading to QI-adverseness
Puerperal vessels of the uterus inanition, cold-evil take advantage of a weak point in opponent's defence in invade, blood is cold coagulation, the stasis of blood is stagnant not all right, lochia is puckery few, blood stasis leading to QI-adverseness, upset the mind, faint and cause.
The treatment of puerperal blood faints, first when distinguishing its deficiency and excess, distinguish the depletion syndrome and excess syndrome of stroke.Primary disease belongs to puerperal.Three punchings " scope, deficiency and excess all belongs to severe crisis, must give treatment in time.
One, type of deficiency of blood and exhaustion of QI
Main syndromes: new producing dehematized too much, swoons suddenly, pale complexion, and cardiopalmus feedback is vexed, and very dusk is not known people, and eye is remained silent out, and hands spreads cold extremities, dripping cold sweat, light red tongue, tongue is few, faint pulse being about to disappear or floating large and empty.
Syndrome analysis: blood goes too much, and the heart is become homeless foster, the mind being out of control, order swoons, and cardiopalmus is muddled vexed, or dusk is not known people; Cloudy blood sudden collapse, can not sending nutrient upward to eye, closes the eyes and emits eye to close; Excessive bleeding associated with exhaustion of QI, spleen sun is on the decline, therefore pale complexion, mouth is opened, hands spreads cold extremities; Battalion is cloudy sudden and violent empty, and lonely sun leaks, dripping cold sweat.Light red tongue, tongue is few. and faint pulse being about to disappear or floating large and empty is levying of blood deficiency QI prostration.
Two, blood stasis leading to QI-adverseness type
Main syndromes: lochiostasis, or under also very few, lower abdomen pain with tenderness, very fullness in the epigastrium is vexed, rough dyspnea with rapid and short breath, nausea and vomiting, coma locked mouth, syncope, two hold fist, purplish complexion, words purple is dim, hesitant pulse is strong.
Syndrome analysis: new to produce sense cold, inside attacks in born of the same parents, and the turbid liquid of remaining blood is met and coldly stagnated, stop holding in interior and must not go out down, therefore retention of lochia, or under also very few; Blood-stasis internal-depression, therefore lower abdomen pain with tenderness; Deteriorated blood stops, and functional activity of QI being not smooth is made a psychological attack, attacked lung on contrary, attacks stomach, and make a psychological attack and upset gods, clear key obturation, so that coma locked mouth, syncope, attacks the duty of impairment of purifying function of the lung of lung, and disease sees that fullness in the epigastrium is vexed, and rough dyspnea with rapid and short breath is attacked stomach-QI being unable to descend normally of stomach, and is seen nausea and vomiting; In blood stasis, stop, muscle arteries and veins loses supports and contracture, therefore two hold fist, is resembling of excess syndrome of stroke.Purplish complexion, words purple is dim, and hesitant pulse is strong, is levying of blood stasis.
At present, the medicine for the treatment of puerperal blood faints is more, but is mostly Western medicine.Western medicine instant effect, but toxic and side effects is larger, easily leaves over sequela.Clinically, treatment by Chinese herbs puerperal blood faints is also more common, but takes trouble, need patient's decoction, moreover onset is slower, is unfavorable for that patient body recovers.
Summary of the invention
In order to overcome deficiency of the prior art, the invention provides a kind of Chinese medicine composition for the treatment of puerperal blood faints and preparation method thereof.
In order to solve the problems of the technologies described above, the technical solution used in the present invention is as follows: a kind of Chinese medicine composition for the treatment of puerperal blood faints and preparation method thereof, is made up of each component of following parts by weight:
Herba Leonuri 5-50 part, Rhizoma Zingiberis Recens 5-20 part, Fructus Jujubae 1-20 part, Radix Ginseng 1-10 part, Radix Astragali 1-20 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Radix Angelicae Sinensis 1-10 part, Flos Carthami 1-5 part, Fructus Lycii 5-20 part, Radix Paeoniae Rubra 1-15 part, Colla Corii Asini 1-20 part, Rhizoma Chuanxiong 5-20 part, Radix Curcumae 1-10 part, Radix Glycyrrhizae 5-15 part, Folium Nelumbinis 1-10 part, Herba Ecliptae 5-20 part, Benzoinum 1-10 part, Radix Polygoni Multiflori 5-20 part, Semen Persicae 5-20 part, Radix Rehmanniae Preparata 5-10 part, Rhizoma Cyperi 5-10 part.
Treat a Chinese medicine composition for puerperal blood faints, also can be formed by each component of following parts by weight:
Herba Leonuri 5-25 part, Rhizoma Zingiberis Recens 5-15 part, Fructus Jujubae 1-10 part, Radix Ginseng 1-5 part, Radix Astragali 1-15 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Radix Angelicae Sinensis 1-5 part, Flos Carthami 1-3 part, Fructus Lycii 5-15 part, Radix Paeoniae Rubra 1-10 part, Colla Corii Asini 1-15 part, Rhizoma Chuanxiong 5-15 part, Radix Curcumae 1-8 part, Radix Glycyrrhizae 5-10 part, Folium Nelumbinis 1-8 part, Herba Ecliptae 5-15 part, Benzoinum 1-8 part, Radix Polygoni Multiflori 5-18 part, Semen Persicae 5-15 part, Radix Rehmanniae Preparata 5-8 part, Rhizoma Cyperi 5-7 part.
Treat a Chinese medicine composition for puerperal blood faints, also can be formed by each component of following parts by weight:
Herba Leonuri 5-10 part, Rhizoma Zingiberis Recens 5-10 part, Fructus Jujubae 1-5 part, Radix Ginseng 1-3 part, Radix Astragali 1-10 part, Rhizoma Atractylodis Macrocephalae 5-8 part, Radix Angelicae Sinensis 1-3 part, Flos Carthami 1-2 part, Fructus Lycii 5-10 part, Radix Paeoniae Rubra 1-6 part, Colla Corii Asini 1-10 part, Rhizoma Chuanxiong 5-10 part, Radix Curcumae 1-5 part, Radix Glycyrrhizae 5-8 part, Folium Nelumbinis 1-5 part, Herba Ecliptae 5-10 part, Benzoinum 1-5 part, Radix Polygoni Multiflori 5-10 part, Semen Persicae 5-10 part, Radix Rehmanniae Preparata 5-6 part, Rhizoma Cyperi 5-6 part.
Treat a Chinese medicine composition for puerperal blood faints, can in described Chinese medicine composition, further add Radix Notoginseng, described Radix Notoginseng is Radix Notoginseng 5-20 part at the addition of described Chinese medicine composition.
Described Chinese medicine composition can be prepared into tablet, capsule, powder as required.
The preparation method of Chinese medicine composition of the present invention, comprises the following steps:
The first step, puts into water by Rhizoma Zingiberis Recens, Fructus Jujubae, Fructus Lycii and Radix Notoginseng and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, the Chinese medicine after pulverizing is crossed to 100 mesh sieves and obtain component 1;
Second step, by Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Flos Carthami, Fructus Lycii, Radix Paeoniae Rubra, Colla Corii Asini, Rhizoma Chuanxiong, Radix Curcumae, Radix Glycyrrhizae is put into water and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, in the ethanol that adds 5-10 doubly to measure the Chinese medicinal powder after pulverizing, soak 2 hours, reflux, extract, 2 times～4 times, filters, merging filtrate, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, the extractum of 1.3-1.5 when ultrafiltrate concentrating under reduced pressure relative density is 70 DEG C, heating is concentrated into paste, paste is dry, in super micron mill, pulverize 10 minutes～20 minutes, become component 2;
The 3rd step, puts into Folium Nelumbinis, Herba Ecliptae, Benzoinum, Radix Polygoni Multiflori, Semen Persicae, Radix Rehmanniae Preparata, Rhizoma Cyperi water and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, add the decocting that 1-5 doubly measures to boil 1～5 hour the Chinese medicinal powder after pulverizing, decoction liquor is filtered, collect filtrate, boil 2～4 hours adding in filtering residue with respect to its quality 1-3 decocting doubly, decoction liquor is filtered, collect filtrate, finally twice filtrate is merged to heating and be concentrated into extractum, by extract dry, in super micron mill, pulverize 10 minutes～20 minutes, become component 3;
The 4th step, by component 1, component 2 and component 3 mix homogeneously, adds adjuvant to obtain different dosage form according to different dosage form;
In the time that the dosage form of described Chinese medicine composition is tablet, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, add wetting agent and adhesive to carry out wet granulation, and dry, add adjuvant tabletting to obtain tablet.
In the time that the dosage form of described Chinese medicine composition is powder, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, then add the starch mix homogeneously with respect to 2～5 times of its quality, ozone sterilization 30 minutes, is prepared into powder.
In the time that the dosage form of described Chinese medicine composition is capsule, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, then add capsule adjuvant, mix homogeneously, ozone sterilization 30 minutes, finally adopts capsule machine that mixed powder is incapsulated.
Described component 1, component 2 and the equal ultraviolet sterilization 1-2 hour of component 3 drug powder.In described Chinese medicine, the pharmacology of each component is as follows:
Herba Leonuri, has another name called: Herba Leonuri, Muscovitum grass.Acrid in the mouth hardship, cool, invigorates blood circulation, blood stasis dispelling, regulating menstruation, water disappears.Control menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Promoting tissue regeneration by removing blood stasis, can be used for again traumatic injury, also has certain curative effect for women by damp and hot pelvic inflammation.Anemia of pregnant woman's forbidding.Without the stasis of blood, stagnant and deficiency of YIN insufficiency of blood person avoids use.
Rhizoma Zingiberis Recens, another name has race, hundred peppery clouds.Pungent and loose temperature, strengthening the spleen stomach, kind warming middle-JIAO to send down the adverse QI preventing or arresting vomiting, the painful abdominal mass that disappears that dehumidifies, eliminating phlegm and stopping cough, taking stopping nausea and vomiting by lowering the adverse flow of QI as long.Antioxidation, suppresses tumor, and appetite promoting and the spleen strengthening promotes appetite, and sunstroke prevention, lower the temperature, refresh oneself, disinfecting detoxifying, reducing swelling and alleviating pain, carsickness-proof, only nausea and vomiting, alleviates waist shoulder pain, and the diseases such as neurasthenia, dizziness, agitation are had to good efficacy.Yin asthenia generating intrinsic heat and excess-heat disease are prohibited clothes.
Fructus Jujubae, sweet in the mouth is warm in nature, spleen reinforcing stomach function regulating, and supplementing QI for promoting the production of body fluid adjusts battalion to defend, and separates poison of drug.Cure mainly insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid deficiency, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.In " herbal classic ", be recorded, Fructus Jujubae is returned taste warp, has the function of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine; All have damp-phlegm, stagnant, tooth disease, a worm patient, all unsuitable.
Radix Ginseng, sweet, micro-hardship, flat.Return spleen, lung, heart channel.Strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, and invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock.
The Radix Astragali, tepor; Sweet; Return spleen, lung meridian.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
The Rhizoma Atractylodis Macrocephalae, temperature, bitter, sweet; Return spleen, stomach warp.Function cures mainly: air making-up and spleen enlivening, and dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Yin asthenia generating intrinsic heat, the careful clothes of body fluid loss person; Inside there is the stagnant person of excess pathogen harmony to prohibit clothes.
Radix Angelicae Sinensis, Radix Angelicae Sinensis is used for enriching blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Cure mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Flos Carthami, has another name called: champac, and nature and flavor are pungent, temperature; Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea ， mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Fructus Lycii, another name Gou Qizi, the red reality of Fructus Lycii.Feeble QI, sweet, the micro-acid of taste.Fructus Lycii is for nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; The expensive essence of sexual impotence; Cough due to consumptive disease; The taking fluids profusely of quenching one's thirst.
Radix Rehmanniae Preparata, has another name called: Radix Rehmanniae Preparata.Tepor; Sweet; Return liver, kidney channel.The YIN nourishing of enriching blood, beneficial essence is filled out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.Weakness of the spleen and stomach, stagnation of QI abundant expectoration, the careful clothes of abdominal distention loose stool person.
Radix Paeoniae Rubra, another name: wooden Radix Paeoniae, red Radix Paeoniae.Be slightly cold; Bitter; Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, abdominal mass stomachache, injury from falling down, carbuncle skin infection.Yang deficiency, blood deficiency are without the card of the stasis of blood and the carbuncle careful clothes of person of having burst.Should not be with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.
Colla Corii Asini, another name: Fu causes glue, Colla Corii Asini.Meridian distribution of property and flavor: flat; Sweet; Return lung, kidney, Liver Channel.Enrich blood, hemostasis, YIN nourishing intestine moistening.For blood deficiency and yellow complexion, dizzy, cardiopalmus; Multiple go out blood disorder; Yin deficiency syndrome and dryness syndrome.Weakness of the spleen and stomach, the careful clothes of dyspepsia person.
Rhizoma Chuanxiong, another name: rhizome of chuanxiong Qiong, Rhizoma Chuanxiong.Nature and flavor: pungent, temperature.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea ， mass in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Curcumae, another name: Huang Yu.Meridian distribution of property and flavor: cold; Pungent, bitter; Return liver, gallbladder, heart channel.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.Asthenia of qi and blood and the stagnant and deficiency of YIN person of losing blood prohibits clothes, the careful clothes of anemia of pregnant woman without the stasis of blood.Should not be with Flos Caryophylli, Fructus Caryophylli with using.
Radix Glycyrrhizae, another name: Glycyrrhizae, close sweet.Meridian distribution of property and flavor: flat; Sweet; GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Should not be with Radix Euphorbiae Pekinensis, Flos Genkwa, Radix Kansui, Sargassum with using.
Folium Nelumbinis, another name: raw Folium Nelumbinis, dry Folium Nelumbinis.Meridian distribution of property and flavor: flat; Bitter; Return liver, spleen, stomach warp.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood is told nosebleed, the metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding.For multiple hemorrhage and puerperal blood faints.The careful clothes of the thin asthenia of qi and blood weak person of body.
Herba Ecliptae, another name: Herba Ecliptae.Meridian distribution of property and flavor: cold; Sweet, sour; Return liver, kidney channel.Nourishing the liver and kidney, cooling blood for hemostasis.For odontoseisis, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, YinXuXueRe, haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.The careful clothes of Deficiency and coldness of spleen and stomach person.
Benzoinum, another name: clumsy shellfish Luo Xiang.Meridian distribution of property and flavor: flat; Pungent, bitter; GUIXIN, liver, spleen channel.The refreshing clearly circulation of qi promoting of having one's ideas straightened out, invigorates blood circulation, pain relieving.For apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, trusted subordinate's pain, puerperal blood deficiency, infantile convulsion.Deficiency of vital energy deficiency, the careful clothes of hyperactivity of fire caused by deficiency of YIN person.
Radix Polygoni Multiflori, another name: the Radix Polygoni Multiflori, Herba Stellariae Saxatilis.Gas is without, bitter and puckery flavor.Tonifying liver, kidney tonifying, nourishes blood, and dispels the wind.Control hepatic and renal YIN deficiency, sending out must be early white, blood deficiency dizziness, and waist knee joint weakness, muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Radix Polygoni Multiflori Preparata invigorating the liver and kidney, benefiting essence-blood, black beard and hair, strengthening bone and muscle; For vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, neurasthenia, hyperlipidemia.Diarrhea with loose stool and have damp-phlegm person is unsuitable.
Semen Persicae, another name: Semen Persicae.Meridian distribution of property and flavor: flat; Bitter, sweet; GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, injury from falling down, dryness of the intestine constipation.Woman and prohibit clothes without blood stasis blood person.
Rhizoma Cyperi, another name: passeris montani saturati head perfume (or spice), cyperi rhizoma.Meridian distribution of property and flavor: flat; Pungent, micro-hardship, micro-sweet; Return liver, spleen, tri-jiao channel.Promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.The deficiency of vital energy is without the careful clothes of stagnant person; The deficiency of YIN, heat in blood person prohibit clothes.
Radix Notoginseng, has another name called: Radix Notoginseng, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae).Sweet in the mouth, micro-hardship, warm in nature, return liver, stomach, the heart, lung and large intestine channel.The effect of tool hemostasis dissipating blood stasis, subduing swelling and relieving pain, the clots absorbing of promoting blood circulation.Cure mainly to fall and flutter congestive edema, thoracic obstruction angor, lump in the abdomen, blood stasis amenorrhea, the cloudy stomachache of the stasis of blood in puerperal, sore, carbuncle and painful swelling etc." jade is seized medicine solution " day: " all puerperal, menstrual period, traumatic injury, carbuncle, all blood stasis are all broken: all nosebleeds, metrorrhagia, knife injury, arrow of telling are penetrated, and all fresh blood all stop." taboo: dysmenorrhea, menoxenia etc. due to deficiency of qi and blood.
The present invention can blood circulation promoting and blood stasis dispelling, QI invigorating, and regulating QI to relieve pain, strengthens uterine contraction amplitude, reduces postpartum hemorrhage, and enhancing human body immunity power improves body hemopoietic function.The present invention adopts pure Chinese medicinal preparation, and safety non-pollution has no side effect, and formula rationally, evident in efficacy, has no adverse reaction and toxic and side effects.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the parts by weight of effective ingredient of the present invention are: 5 parts of Herba Leonuris, 5 parts, Rhizoma Zingiberis Recens, 1 part of Fructus Jujubae, 1 part of Radix Ginseng, 1 part of the Radix Astragali, 5 parts of the Rhizoma Atractylodis Macrocephalaes, 1 part of Radix Angelicae Sinensis, 1 part, Flos Carthami, 5 parts of Fructus Lyciis, 1 part of Radix Paeoniae Rubra, 1 part, Colla Corii Asini, 5 parts of Rhizoma Chuanxiongs, 1 part of Radix Curcumae, 5 parts, Radix Glycyrrhizae, 1 part, Folium Nelumbinis, 5 parts of Herba Ecliptaes, 1 part of Benzoinum, 10 parts of Radix Polygoni Multiflori, 10 parts, Semen Persicae, 5 parts of Radix Rehmanniae Preparata, 5 parts of Rhizoma Cyperis.
The present invention further adds Radix Notoginseng in described Chinese medicine composition, and described Radix Notoginseng is 5 parts of Radix Notoginseng at the addition of described Chinese medicine composition.
Described Chinese medicine composition can be prepared into tablet, capsule, powder according to needs very much.
Preparation method of the present invention, comprises the following steps:
The first step, puts into water by Rhizoma Zingiberis Recens, Fructus Jujubae, Fructus Lycii and Radix Notoginseng and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, the Chinese medicine after pulverizing is crossed to 100 mesh sieves and obtain A group drug component 1;
Second step, by Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Flos Carthami, Fructus Lycii, Radix Paeoniae Rubra, Colla Corii Asini, Rhizoma Chuanxiong, Radix Curcumae, Radix Glycyrrhizae is put into water and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, in the ethanol that adds 5-10 doubly to measure the Chinese medicinal powder after pulverizing, soak 2 hours, reflux, extract, 2 times～4 times, filters, merging filtrate, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, the extractum of 1.3-1.5 when ultrafiltrate concentrating under reduced pressure relative density is 70 DEG C, heating is concentrated into paste, paste is dry, in super micron mill, pulverize 10 minutes～20 minutes, become component 2;
The 3rd step, puts into Folium Nelumbinis, Herba Ecliptae, Benzoinum, Radix Polygoni Multiflori, Semen Persicae, Radix Rehmanniae Preparata, Rhizoma Cyperi water and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, add the decocting that 1-5 doubly measures to boil 1～5 hour the Chinese medicinal powder after pulverizing, decoction liquor is filtered, collect filtrate, boil 2～4 hours adding in filtering residue with respect to its quality 1-3 decocting doubly, decoction liquor is filtered, collect filtrate, finally twice filtrate is merged to heating and be concentrated into extractum, by extract dry, in super micron mill, pulverize 10 minutes～20 minutes, become component 3;
The 4th step, by component 1, component 2 and component 3 mix homogeneously, adds adjuvant to obtain different dosage form according to different dosage form;
In the time that the dosage form of described Chinese medicine composition is tablet, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, add wetting agent and adhesive to carry out wet granulation, and dry, add adjuvant magnesium stearate tabletting to obtain tablet.
In the time that the dosage form of described Chinese medicine composition is powder, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, then add the starch mix homogeneously with respect to 2～5 times of its quality, and ozone sterilization 30 minutes, pack is prepared into powder.
In the time that the dosage form of described Chinese medicine composition is capsule, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, then add capsule adjuvant, mix homogeneously, ozone sterilization 30 minutes, finally adopts capsule machine that mixed powder is incapsulated.
Embodiment 2
Raw material composition and the parts by weight of active ingredient of the present invention are 8 parts of Herba Leonuris, 8 parts, Rhizoma Zingiberis Recens, 4 parts of Fructus Jujubaes, 2 parts of Radix Ginsengs, 5 parts of the Radixs Astragali, 7 parts of the Rhizoma Atractylodis Macrocephalaes, 2 parts of Radix Angelicae Sinensis, 1 part, Flos Carthami, 6 parts of Fructus Lyciis, 3 parts of Radix Paeoniae Rubra, 4 parts, Colla Corii Asini, 6 parts of Rhizoma Chuanxiongs, 4 parts of Radix Curcumaes, 7 parts, Radix Glycyrrhizae, 4 parts, Folium Nelumbinis, 6 parts of Herba Ecliptaes, 4 parts of Benzoinumes, 7 parts of Radix Polygoni Multiflori, 8 parts, Semen Persicae, 5 parts of Radix Rehmanniae Preparata, 5 parts of Rhizoma Cyperis.
Method for preparing tablet thereof is as embodiment 1
Powder preparation method is as embodiment 1
Capsule preparation method thereof is as embodiment 1
Embodiment 3
Raw material composition and the parts by weight of effective ingredient of the present invention are: 10 parts of Herba Leonuris, 10 parts, Rhizoma Zingiberis Recens, 5 parts of Fructus Jujubaes, 3 parts of Radix Ginsengs, 10 parts of the Radixs Astragali, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts of Radix Angelicae Sinensis, 2 parts, Flos Carthami, 10 parts of Fructus Lyciis, 6 parts of Radix Paeoniae Rubra, 10 parts, Colla Corii Asini, 10 parts of Rhizoma Chuanxiongs, 5 parts of Radix Curcumaes, 8 parts, Radix Glycyrrhizae, 5 parts, Folium Nelumbinis, 10 parts of Herba Ecliptaes, 5 parts of Benzoinumes, 10 parts of Radix Polygoni Multiflori, 10 parts, Semen Persicae, 6 parts of Radix Rehmanniae Preparata, 6 parts of Rhizoma Cyperis.
Method for preparing tablet thereof is as embodiment 1
Powder preparation method is as embodiment 1
Capsule preparation method thereof is as embodiment 1
Toxicity test:
Laboratory animal
1 materials and methods
1.1 animal white mice, body weight (20 ± 5) g, male and female half and half Qingdao City's laboratory animal and zoopery center provide.
1.2 trial drug Chinese medicine composition of the present invention is studied white mice toxic action.
2 methods
2.1 LD50 tests: this experiment adopts improvement karber's method, first white mice is divided into 5 groups at random, ten every group, male and female half and half, are scattered in distilled water ultrasonic medicine of the present invention, are made into Cmax, give white mice maximum dosage according to clinical animal experiment standard, described dosage is followed successively by 26,24.5,20.1,16.8,14.7,11.4,9.2,7.8 (gkg
-1), give white mice fasting after 18 hours, a bu three times administration, at least 2 hours, each administration time interval, each 0.5ml, after administration, observes mice dying situation.
2.2 MTD tests: get 20 of white mice, each 10 of male and female.Be scattered in distilled water ultrasonic medicine of the present invention, be made into Cmax, give white mice maximum tolerated dose according to clinical animal experiment standard, can twitch and be as the criterion to inject irrigation stomach device.Give white mice fasting after 18 hours, a bu three times administration, at least 2 hours, each administration time interval, each 0.5ml (every milliliter contained 0.054g), total dosage is 17.6g crude drug/kg.d, after administration, within continuous seven days, observes mice dying situation.
3 experimental results
When result demonstration is used maximum acceptable concentration to give white mice medication, do not occur mice dying, LD50 result does not detect.MTD test drug withdrawal is after three days, observe white mice behavioral activity, ingest, the general variation and survival condition such as drinking-water, hair, feces.Within 7 days, dissect afterwards the mode of appearance of the white mice perusal heart, liver, spleen, lung, kidney, and Liver of Mice is carried out to pathologic section, observe its pathological changes situation, result shows and has no adverse reaction, and shows that acute toxicity of the present invention is minimum.MTD＞17.6g/Kg.d。
4 long term toxicity test data of the present invention
Get 30 white mice, be divided into three groups, 10 every group, male and female half and half, give gastric infusion to three groups of white mice, test duration 20 weeks, and wherein first group gives normal saline gavage; Second group gives medicine gavage of the present invention, and drug dose is 0.25,2.5 and 10g/kg.d, and the 3rd group gives lovastatin gavage, and dosage is 0.5mg, 5.0mg and 20.0mg/g.d.During administration, white mice is carried out to drug toxicity evaluation, evaluation criterion comprises clinical manifestation, histopathology, hematology etc.Result shows: two dosage groups that show the 3rd group of lovastatin concentration 5.0mg and 20.0mg/g.d of toxicity maximum, and two groups of white mice have all showed abnormal reaction and the symptoms such as sialorrhea, diarrhoea, step, and two groups of Mice weight averages have and alleviate; Histopathological analysis result shows have and Liver and kidney pathological change like the mankind in lovastatin 20mg/kg.d dosage group; Blood biochemical detects and shows that erythrocyte, hemoglobin and platelet count all obviously decline, and quantity of leucocyte all increases.There is not above-mentioned similar reaction at viewing duration in of the present invention group and normal saline group and lovastatin 0.5mg/kg.d dosage group.Result of the test shows that the toxic and side effects that the present invention both can reduce lovastatin also can increase clinical non-toxic.
Clinical trial:
Clinical puerperal blood faints patient 188 examples of random screening, random packet, is experimental group and matched group, every group of 94 examples.
Therapeutic scheme:
Experimental group is taken tablet prepared by the embodiment of the present invention, and every day three times, each two 3 days is a course for the treatment of.
Matched group is taken merciful ferry capsule, one time 5,2 times on the one, sooner or later respectively once.
Criterion of therapeutical effect:
Therapeutic scheme: take the circumstances into consideration administration according to the state of an illness.
The standard of curative effect evaluation: treatment evaluation criteria, " traditional Chinese medical science disease Standardization of diagnosis and curative effect " formulated according to State Administration of Traditional Chinese Medicine judged
Cure: have a dizzy spell, ambition is full vexed, nausea and vomiting, what is said or talked about is gushed out of breath, vexed uneasiness, coma locked mouth, the symptoms such as syncope disappear completely, and the positive ordinary index of blood pressure and blood sugar recovery, without any discomfort symptom;
Effective: have a dizzy spell, ambition is full vexed, nausea and vomiting, what is said or talked about is gushed out of breath, vexed uneasiness, coma locked mouth, the symptoms such as syncope obviously alleviate, and blood pressure and blood glucose recover positive ordinary index substantially, need continual cure;
Invalid: symptom does not have any improvement, even there is the trend increasing the weight of;
Therapeutic outcome (in table 1)
Table 1 liang group therapeutic outcome
Table 1 shows, experimental group cures, effectively, total effective rate is all obviously better than matched group.Illustrate that the present invention has than the better curative effect of merciful ferry capsule.
Puerperal blood faints is divided into type of deficiency of blood and exhaustion of QI and blood stasis leading to QI-adverseness type according to traditional Chinese medical science standard.
Table 2 is the relation between two set types and treatment curative effect
There is above table data show, the present invention all has good curative effect total effective rate all more than 70% for these two types, and this experimental data shows that medicine of the present invention all has good curative effect for blood deficiency and Qi exhaustion type post partum blood faint and blood stasis leading to QI-adverseness type puerperal blood faints.
Feature case is as follows:
Case 1 Liu 27
Medical history: have a surplus 6 days so far puerperal, frequently occurs spinning sensation, sensation limbs fatigue, can not normally do, and by the food of edible nourishing class, the state of an illness is slightly improved, but occurs all the time unable phenomenon.The antenatal physical qualification of puerpera is fair, without the dizzy medical history of repeatability.
Clinical symptoms: brains is dizzy, blurred vision, myasthenia of limbs, can not play seat.
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes tablet of the present invention every day, and each two, every day 3 times.Take medicine after 3 days, dizzy number of times reduces, normal visual acuity, and appetite strengthens, and takes medicine after 6 days, does not occur dizzy phenomenon, can normally do, and spirit is good.
Case 2 Zhangs 26
Medical history: dizziness in puerperal, unable, continues a couple of days.Hemorrhage more when parturient childbirth, antenatal physical qualification is fair.
Clinical symptoms: swoon suddenly, pale complexion, cardiopalmus feedback is vexed, dripping cold sweat
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes powder of the present invention every day, each bag, every day 3 times.Take medicine after 5 days, complexion is obviously improved, and the phenomenon that is in a cold sweat alleviates.Take medicine after 10 days, do not occur the phenomenon that swoons, breathe smooth and easy, better spiritual.
Case 3 Zhengs 28
Medical history: puerperal pale complexion, limbs fatigue, continue a few days.
Clinical symptoms: even have dusk not know people, and eye is remained silent out, and hands spreads cold extremities, light red tongue, tongue is few.
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes tablet of the present invention every day, and each two, every day 3 times.Take medicine after 7 days, dizzy number of times reduces, and appetite strengthens, and takes medicine after 15 days, and dizzy symptom obviously reduces, and complexion is gradually red, and spirit is better.
Case 4 Qin so-and-so 28
Medical history: phenomenon uncomfortable in chest, unable appears in puerpera from puerperal, by the food of more edible nourishing classes, slightly sense is strong, can do voluntarily, but have uncomfortable in chestly, is in a cold sweat.
Clinical symptoms: myasthenia of limbs, emit cold sweat, occur once in a while dizzy, uncomfortable in chest.
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes tablet of the present invention every day, and each two, every day 3 times.Take medicine after 5 days, can normally do, emit cold sweat phenomenon to alleviate.Take medicine after 8 days, do not occur during this time dizzyly, mental restoration is normal.
Case 5 kings so-and-so 30
, without obviously bad phenomenon appearance, there is limply phenomenon puerperal in medical history: the antenatal physical qualification of puerpera is better, and with short of breath, through Drug therapy and tonic, take a favorable turn without force phenomenon, but uncomfortable in chest, the short of breath persistent period is longer, and so far, first quarter moon is had a surplus.
Clinical symptoms: chest distress and palpitation symptoms, breathe slightly hurriedly limbs fatigue, pale complexion.
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes powder of the present invention every day, each 2 bags, every day 3 times.Take medicine after 3 days, breathe normally, appetite strengthens, take medicine after 6 days,, complexion is gradually red, can normally do, and phenomenon uncomfortable in chest disappears.
Case 6 Liu so-and-so 27
Medical history: puerpera's trick in puerperal is cooler, is easily in a cold sweat, and after feed, often with vomiting phenomenon, and food-intake is few, in one week puerperal, occurs the phenomenon that swoons.
Clinical symptoms: occasionally now swoon, trick is ice-cold, is in a cold sweat, often nausea and vomiting.
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes powder of the present invention every day, each 2 bags, every day 3 times.Take medicine after 3 days, vomiting phenomenon reduces, and trick is warm normal, and appetite strengthens, and takes medicine after 7 days, does not occur during this time the phenomenon that swoons, and mental restoration is normal.
Case 7 poplars 26
, there is nausea and vomiting phenomenon puerperal in medical history: the antenatal physical qualification of puerpera is good, lower abdomen is with tenderness, and words are blue, ate after a little nourishing group foods, and the purple dim phenomenon of words slightly take a favorable turn, can normally do, but often with uncomfortable in chest, the phenomenon of feeling sick.
Clinical symptoms: feel sick and retch, tachypnea is uncomfortable in chest, and lower abdomen has tenderness.Words purple is dim.
Therapeutic process: Chinese medical discrimination belongs to bruise disease, takes powder of the present invention every day, each 2 bags, every day 3 times.Take medicine after 8 days, dizzy number of times reduces, and appetite strengthens, and takes medicine after 17 days, and the retch symptom of feeling sick obviously reduces, and complexion is gradually red, symptom be improved significantly, the sense of lower abdomen tenderness disappears.
The above; it is only most preferred embodiment of the present invention; not the present invention is done to any pro forma restriction; any those of ordinary skill in the art; do not departing from technical solution of the present invention scope situation; utilize the method content of above-mentioned announcement to make many possible variations and modification to technical solution of the present invention, all belong to the scope of claims protection.
Claims (10)
1. a Chinese medicine composition for the treatment of puerperal blood faints, is characterized in that: the each component by following parts by weight forms:
Herba Leonuri 5-50 part, Rhizoma Zingiberis Recens 5-20 part, Fructus Jujubae 1-20 part, Radix Ginseng 1-10 part, Radix Astragali 1-20 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Radix Angelicae Sinensis 1-10 part, Flos Carthami 1-5 part, Fructus Lycii 5-20 part, Radix Paeoniae Rubra 1-15 part, Colla Corii Asini 1-20 part, Rhizoma Chuanxiong 5-20 part, Radix Curcumae 1-10 part, Radix Glycyrrhizae 5-15 part, Folium Nelumbinis 1-10 part, Herba Ecliptae 5-20 part, Benzoinum 1-10 part, Radix Polygoni Multiflori 5-20 part, Semen Persicae 5-20 part, Radix Rehmanniae Preparata 5-10 part, Rhizoma Cyperi 5-10 part.
2. a kind of Chinese medicine composition for the treatment of puerperal blood faints according to claim 1, is characterized in that: the each component by following parts by weight forms:
Herba Leonuri 5-25 part, Rhizoma Zingiberis Recens 5-15 part, Fructus Jujubae 1-10 part, Radix Ginseng 1-5 part, Radix Astragali 1-15 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Radix Angelicae Sinensis 1-5 part, Flos Carthami 1-3 part, Fructus Lycii 5-15 part, Radix Paeoniae Rubra 1-10 part, Colla Corii Asini 1-15 part, Rhizoma Chuanxiong 5-15 part, Radix Curcumae 1-8 part, Radix Glycyrrhizae 5-10 part, Folium Nelumbinis 1-8 part, Herba Ecliptae 5-15 part, Benzoinum 1-8 part, Radix Polygoni Multiflori 5-18 part, Semen Persicae 5-15 part, Radix Rehmanniae Preparata 5-8 part, Rhizoma Cyperi 5-7 part.
3. a kind of Chinese medicine composition for the treatment of puerperal blood faints according to claim 1, is characterized in that: the each component by following parts by weight forms:
Herba Leonuri 5-10 part, Rhizoma Zingiberis Recens 5-10 part, Fructus Jujubae 1-5 part, Radix Ginseng 1-3 part, Radix Astragali 1-10 part, Rhizoma Atractylodis Macrocephalae 5-8 part, Radix Angelicae Sinensis 1-3 part, Flos Carthami 1-2 part, Fructus Lycii 5-10 part, Radix Paeoniae Rubra 1-6 part, Colla Corii Asini 1-10 part, Rhizoma Chuanxiong 5-10 part, Radix Curcumae 1-5 part, Radix Glycyrrhizae 5-8 part, Folium Nelumbinis 1-5 part, Herba Ecliptae 5-10 part, Benzoinum 1-5 part, Radix Polygoni Multiflori 5-10 part, Semen Persicae 5-10 part, Radix Rehmanniae Preparata 5-6 part, Rhizoma Cyperi 5-6 part.
4. a kind of Chinese medicine composition for the treatment of puerperal blood faints according to claim 1, is characterized in that: can in described Chinese medicine composition, further add Radix Notoginseng, described Radix Notoginseng is Radix Notoginseng 5-20 part at the addition of described Chinese medicine composition.
5. a kind of Chinese medicine composition for the treatment of puerperal blood faints according to claim 1, is characterized in that: described Chinese medicine composition can be prepared into tablet, capsule, powder as required.
6. the preparation method of a kind of Chinese medicine composition for the treatment of puerperal blood faints according to claim 3, is characterized in that: comprise the following steps:
The first step, puts into water by Rhizoma Zingiberis Recens, Fructus Jujubae, Fructus Lycii and Radix Notoginseng and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, the Chinese medicine after pulverizing is crossed to 100 mesh sieves and obtain component 1;
Second step, by Radix Ginseng, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Flos Carthami, Fructus Lycii, Radix Paeoniae Rubra, Colla Corii Asini, Rhizoma Chuanxiong, Radix Curcumae, Radix Glycyrrhizae is put into water and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, in the ethanol that adds 5-10 doubly to measure the Chinese medicinal powder after pulverizing, soak 2 hours, reflux, extract, 2 times～4 times, filters, merging filtrate, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, the extractum of 1.3-1.5 when ultrafiltrate concentrating under reduced pressure relative density is 70 DEG C, heating is concentrated into paste, paste is dry, in super micron mill, pulverize 10 minutes～20 minutes, become component 2;
The 3rd step, puts into Folium Nelumbinis, Herba Ecliptae, Benzoinum, Radix Polygoni Multiflori, Semen Persicae, Radix Rehmanniae Preparata, Rhizoma Cyperi water and rinses, and dries; Proportionally be positioned in super micron mill and pulverize 30 minutes～40 minutes, add the decocting that 1-5 doubly measures to boil 1～5 hour the Chinese medicinal powder after pulverizing, decoction liquor is filtered, collect filtrate, boil 2～4 hours adding in filtering residue with respect to its quality 1-3 decocting doubly, decoction liquor is filtered, collect filtrate, finally twice filtrate is merged to heating and be concentrated into extractum, by extract dry, in super micron mill, pulverize 10 minutes～20 minutes, become component 3;
The 4th step, by component 1, component 2 and component 3 mix homogeneously, adds corresponding adjuvant to obtain different dosage form medicine according to dosage form.
7. the preparation method of a kind of Chinese medicine composition for the treatment of puerperal blood faints as claimed in claim 1, it is characterized in that: in the time that the dosage form of described Chinese medicine composition is tablet, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, add wetting agent and adhesive to carry out wet granulation, dry, add adjuvant tabletting to obtain tablet.
8. the preparation method of a kind of Chinese medicine composition for the treatment of puerperal blood faints as claimed in claim 1, it is characterized in that: in the time that the dosage form of described Chinese medicine composition is powder, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, add again the starch mix homogeneously with respect to 2～5 times of its quality, ozone sterilization 30 minutes, is prepared into powder.
9. the preparation method of a kind of Chinese medicine composition for the treatment of puerperal blood faints as claimed in claim 1, it is characterized in that: in the time that the dosage form of described Chinese medicine composition is capsule, the described the 4th is step by step suddenly: by component 1, component 2 and component 3 mix homogeneously, add again capsule adjuvant, mix homogeneously, ozone sterilization 30 minutes, finally adopts capsule machine that mixed powder is incapsulated.
10. the preparation method of a kind of Chinese medicine composition for the treatment of puerperal blood faints as claimed in claim 6, is characterized in that: component 1, component 2 and the equal ultraviolet sterilization 1-2 hour of component 3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410408842.0A CN104189811A (en) | 2014-08-15 | 2014-08-15 | Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410408842.0A CN104189811A (en) | 2014-08-15 | 2014-08-15 | Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104189811A true CN104189811A (en) | 2014-12-10 |
Family
ID=52075282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410408842.0A Pending CN104189811A (en) | 2014-08-15 | 2014-08-15 | Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104189811A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105521333A (en) * | 2015-12-30 | 2016-04-27 | 张永红 | Foot bathing liquor relieving postpartum anemic fainting and preparing method thereof |
| CN105596527A (en) * | 2016-01-14 | 2016-05-25 | 吴媛 | Traditional Chinese medicine for treating postpartum anemic fainting and preparation method thereof |
| CN106266758A (en) * | 2015-06-10 | 2017-01-04 | 王世祥 | A kind of Chinese medicine formula treating blood deficiency |
| CN108567954A (en) * | 2018-01-23 | 2018-09-25 | 夏宝真 | A kind of Chinese medicine composition and its preparation method and application for treating late puerperal hemorrhage |
| CN109925186A (en) * | 2017-12-19 | 2019-06-25 | 王丽 | A kind of postpartum repairs combined complete and its uses technology |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102363022A (en) * | 2011-11-03 | 2012-02-29 | 李光彩 | Chinese medicine for treating postpartum anemic fainting |
-
2014
- 2014-08-15 CN CN201410408842.0A patent/CN104189811A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102363022A (en) * | 2011-11-03 | 2012-02-29 | 李光彩 | Chinese medicine for treating postpartum anemic fainting |
Non-Patent Citations (4)
| Title |
|---|
| 哈孝贤: "产后出血漫谈", 《天津中医学院学报》 * |
| 林强等: ""麒麟桂红饮"治疗产后血晕80例", 《江苏中医药》 * |
| 梁秀芳: "产后血晕验案2则", 《四川中医》 * |
| 田岩: "产后病的病理特点及辨证施治", 《浙江中医杂志》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266758A (en) * | 2015-06-10 | 2017-01-04 | 王世祥 | A kind of Chinese medicine formula treating blood deficiency |
| CN105521333A (en) * | 2015-12-30 | 2016-04-27 | 张永红 | Foot bathing liquor relieving postpartum anemic fainting and preparing method thereof |
| CN105596527A (en) * | 2016-01-14 | 2016-05-25 | 吴媛 | Traditional Chinese medicine for treating postpartum anemic fainting and preparation method thereof |
| CN109925186A (en) * | 2017-12-19 | 2019-06-25 | 王丽 | A kind of postpartum repairs combined complete and its uses technology |
| CN108567954A (en) * | 2018-01-23 | 2018-09-25 | 夏宝真 | A kind of Chinese medicine composition and its preparation method and application for treating late puerperal hemorrhage |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102166317B (en) | Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis | |
| CN105749179A (en) | Traditional Chinese medicine composition for treating metabolic syndrome | |
| CN105920514A (en) | Traditional Chinese medicinal composition for treating metabolic syndrome | |
| CN103432390B (en) | Medicament for treating coronary heart disease and preparation method thereof | |
| CN104189811A (en) | Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof | |
| CN105664099A (en) | Traditional Chinese medicine composition for warming and invigorating kidney yang and preparation method thereof | |
| CN103394058B (en) | Medicament for treating postpartum disease and preparation method thereof | |
| CN104173773A (en) | Preparation with functions of treating migraine, dispelling wind and promoting blood circulation and preparation methods | |
| CN102302740B (en) | Preparation method of traditional Chinese medicine used for treating thoracic obstructions caused by yin deficiency of heart and kidney | |
| CN105535798A (en) | Novel traditional Chinese medicine composition for treating diarrhea and preparation method thereof | |
| CN103127481B (en) | Drug curing depressive disorder | |
| CN102293964B (en) | Medicine for treating gastric ulcer, and preparation method thereof | |
| CN103301341A (en) | Traditional Chinese medicine composition of treating ischemic cerebral apoplexy | |
| CN103735916B (en) | A kind of medicine for the treatment of the nephrotic syndrome and preparation method thereof | |
| CN104857370A (en) | Traditional Chinese medicine composition for treating breast cancer | |
| CN105727001A (en) | Traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases | |
| CN105362827A (en) | Decoction capable of effectively treating anemia and preparation method thereof | |
| CN105457001A (en) | Medicine for treating attention-deficit hyperactivity disorder and preparation method of medicine | |
| CN101947303B (en) | Drug for radical treatment of hypertension and preparation method thereof | |
| CN104998074A (en) | Traditional Chinese medicine for treating gastropathy and preparation method thereof | |
| CN104547553A (en) | Traditional Chinese medicine for treating nervous endocrine disorder | |
| CN104189615B (en) | Traditional Chinese medicine preparation for treating metrorrhagia and metrostaxis, and preparation method of traditional Chinese medicine preparation | |
| CN105327194A (en) | Medicine for treating anemia and preparing method thereof | |
| CN105343863A (en) | Medicine for treating benign ovarian cyst and preparation method of medicine | |
| CN105412830A (en) | Medicine for treating acute icteric hepatitis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20141210 |
|
| RJ01 | Rejection of invention patent application after publication |