CN105920514A - Traditional Chinese medicinal composition for treating metabolic syndrome - Google Patents
Traditional Chinese medicinal composition for treating metabolic syndrome Download PDFInfo
- Publication number
- CN105920514A CN105920514A CN201610268253.6A CN201610268253A CN105920514A CN 105920514 A CN105920514 A CN 105920514A CN 201610268253 A CN201610268253 A CN 201610268253A CN 105920514 A CN105920514 A CN 105920514A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- semen
- herba
- fructus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 208000001145 Metabolic Syndrome Diseases 0.000 title abstract description 11
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 title abstract description 11
- 239000003814 drug Substances 0.000 claims abstract description 68
- 210000000582 semen Anatomy 0.000 claims abstract description 55
- 238000011282 treatment Methods 0.000 claims abstract description 35
- 229940079593 drug Drugs 0.000 claims abstract description 19
- 241001116389 Aloe Species 0.000 claims abstract description 14
- 235000009797 Lagenaria vulgaris Nutrition 0.000 claims abstract description 14
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 14
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 14
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 14
- 239000009670 cang er zi wan Substances 0.000 claims abstract description 14
- 235000008434 ginseng Nutrition 0.000 claims abstract description 14
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 14
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 13
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 13
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims abstract description 12
- 239000009636 Huang Qi Substances 0.000 claims abstract description 8
- 208000011580 syndromic disease Diseases 0.000 claims description 30
- 230000004060 metabolic process Effects 0.000 claims description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 238000002360 preparation method Methods 0.000 claims description 16
- 241000208340 Araliaceae Species 0.000 claims description 13
- 240000009087 Crescentia cujete Species 0.000 claims description 13
- 235000005983 Crescentia cujete Nutrition 0.000 claims description 13
- 241000628997 Flos Species 0.000 claims description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 13
- 238000009835 boiling Methods 0.000 claims description 10
- 206010020772 Hypertension Diseases 0.000 claims description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 8
- 239000012141 concentrate Substances 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 7
- 239000008187 granular material Substances 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims description 7
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 6
- 201000010099 disease Diseases 0.000 claims description 6
- 239000008188 pellet Substances 0.000 claims description 6
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 claims description 6
- 235000021286 stilbenes Nutrition 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
- 239000006187 pill Substances 0.000 claims description 5
- 239000002552 dosage form Substances 0.000 claims description 4
- 239000003937 drug carrier Substances 0.000 claims description 4
- 201000005577 familial hyperlipidemia Diseases 0.000 claims description 4
- 239000003826 tablet Substances 0.000 claims description 4
- 208000004611 Abdominal Obesity Diseases 0.000 claims description 3
- 244000025254 Cannabis sativa Species 0.000 claims description 3
- 206010065941 Central obesity Diseases 0.000 claims description 3
- 230000002159 abnormal effect Effects 0.000 claims description 3
- 230000023852 carbohydrate metabolic process Effects 0.000 claims description 3
- 235000021256 carbohydrate metabolism Nutrition 0.000 claims description 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 3
- 241000251468 Actinopterygii Species 0.000 claims description 2
- 206010003210 Arteriosclerosis Diseases 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 235000020995 raw meat Nutrition 0.000 claims description 2
- 239000003390 Chinese drug Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000004369 blood Anatomy 0.000 abstract description 46
- 239000008280 blood Substances 0.000 abstract description 46
- 230000000694 effects Effects 0.000 abstract description 12
- 208000008589 Obesity Diseases 0.000 abstract description 6
- 235000020824 obesity Nutrition 0.000 abstract description 6
- 206010022489 Insulin Resistance Diseases 0.000 abstract description 4
- 244000183278 Nephelium litchi Species 0.000 abstract description 4
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract description 4
- 150000002632 lipids Chemical class 0.000 abstract description 3
- 238000012827 research and development Methods 0.000 abstract description 2
- 240000008027 Akebia quinata Species 0.000 abstract 1
- 235000007756 Akebia quinata Nutrition 0.000 abstract 1
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000233839 Commelina communis Species 0.000 abstract 1
- 240000006509 Gynostemma pentaphyllum Species 0.000 abstract 1
- 235000002956 Gynostemma pentaphyllum Nutrition 0.000 abstract 1
- 235000018142 Hedysarum alpinum var americanum Nutrition 0.000 abstract 1
- 240000006461 Hedysarum alpinum var. americanum Species 0.000 abstract 1
- 244000303847 Lagenaria vulgaris Species 0.000 abstract 1
- 240000002853 Nelumbo nucifera Species 0.000 abstract 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 abstract 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000006751 Platycodon Nutrition 0.000 abstract 1
- 244000274050 Platycodon grandiflorum Species 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 240000004922 Vigna radiata Species 0.000 abstract 1
- 235000010721 Vigna radiata var radiata Nutrition 0.000 abstract 1
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 229930189914 platycodon Natural products 0.000 abstract 1
- 235000021018 plums Nutrition 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 description 34
- 235000019634 flavors Nutrition 0.000 description 34
- 230000006870 function Effects 0.000 description 32
- 235000009508 confectionery Nutrition 0.000 description 29
- 210000004185 liver Anatomy 0.000 description 27
- 210000000952 spleen Anatomy 0.000 description 27
- 210000004072 lung Anatomy 0.000 description 26
- 208000002193 Pain Diseases 0.000 description 23
- 230000036407 pain Effects 0.000 description 21
- 210000002784 stomach Anatomy 0.000 description 21
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 14
- 206010012735 Diarrhoea Diseases 0.000 description 13
- 206010012601 diabetes mellitus Diseases 0.000 description 13
- 231100000614 poison Toxicity 0.000 description 13
- 239000000243 solution Substances 0.000 description 12
- 210000002216 heart Anatomy 0.000 description 11
- 206010062717 Increased upper airway secretion Diseases 0.000 description 10
- 210000001015 abdomen Anatomy 0.000 description 10
- 208000026435 phlegm Diseases 0.000 description 10
- 230000001737 promoting effect Effects 0.000 description 10
- 230000008673 vomiting Effects 0.000 description 10
- 206010030113 Oedema Diseases 0.000 description 9
- 210000003734 kidney Anatomy 0.000 description 9
- 206010011224 Cough Diseases 0.000 description 8
- 208000004880 Polyuria Diseases 0.000 description 8
- 206010047700 Vomiting Diseases 0.000 description 8
- 230000035619 diuresis Effects 0.000 description 8
- 231100000252 nontoxic Toxicity 0.000 description 8
- 230000003000 nontoxic effect Effects 0.000 description 8
- 230000008961 swelling Effects 0.000 description 8
- 201000000736 Amenorrhea Diseases 0.000 description 7
- 206010001928 Amenorrhoea Diseases 0.000 description 7
- 206010007247 Carbuncle Diseases 0.000 description 7
- 102000004877 Insulin Human genes 0.000 description 7
- 108090001061 Insulin Proteins 0.000 description 7
- 241000700159 Rattus Species 0.000 description 7
- 208000033809 Suppuration Diseases 0.000 description 7
- 206010042674 Swelling Diseases 0.000 description 7
- 231100000540 amenorrhea Toxicity 0.000 description 7
- 208000001848 dysentery Diseases 0.000 description 7
- 229940125396 insulin Drugs 0.000 description 7
- 210000002429 large intestine Anatomy 0.000 description 7
- 208000030159 metabolic disease Diseases 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 210000000038 chest Anatomy 0.000 description 6
- 230000007812 deficiency Effects 0.000 description 6
- 230000001047 pyretic effect Effects 0.000 description 6
- 230000035922 thirst Effects 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 5
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 5
- 206010010774 Constipation Diseases 0.000 description 5
- 201000004624 Dermatitis Diseases 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 230000037396 body weight Effects 0.000 description 5
- 239000002574 poison Substances 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 208000004998 Abdominal Pain Diseases 0.000 description 4
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical group C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 description 4
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Chemical group C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 description 4
- 208000017170 Lipid metabolism disease Diseases 0.000 description 4
- 206010027514 Metrorrhagia Diseases 0.000 description 4
- 206010030302 Oliguria Diseases 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 230000036528 appetite Effects 0.000 description 4
- 235000019789 appetite Nutrition 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 4
- 229960005370 atorvastatin Drugs 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 210000001124 body fluid Anatomy 0.000 description 4
- 239000010839 body fluid Substances 0.000 description 4
- 235000005911 diet Nutrition 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000002398 materia medica Substances 0.000 description 4
- 235000013372 meat Nutrition 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 208000005171 Dysmenorrhea Diseases 0.000 description 3
- 206010013935 Dysmenorrhoea Diseases 0.000 description 3
- 206010017553 Furuncle Diseases 0.000 description 3
- 206010023126 Jaundice Diseases 0.000 description 3
- 208000019255 Menstrual disease Diseases 0.000 description 3
- 206010033307 Overweight Diseases 0.000 description 3
- 206010033557 Palpitations Diseases 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 208000001431 Psychomotor Agitation Diseases 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- 206010038743 Restlessness Diseases 0.000 description 3
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000037213 diet Effects 0.000 description 3
- 208000001780 epistaxis Diseases 0.000 description 3
- 208000035861 hematochezia Diseases 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
- 230000002218 hypoglycaemic effect Effects 0.000 description 3
- 206010022437 insomnia Diseases 0.000 description 3
- 230000000968 intestinal effect Effects 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 230000001575 pathological effect Effects 0.000 description 3
- 230000007096 poisonous effect Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 206010042772 syncope Diseases 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 241000208365 Celastraceae Species 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 208000001380 Diabetic Ketoacidosis Diseases 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010019909 Hernia Diseases 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- 206010060378 Hyperinsulinaemia Diseases 0.000 description 2
- 206010020710 Hyperphagia Diseases 0.000 description 2
- 208000013016 Hypoglycemia Diseases 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 206010068319 Oropharyngeal pain Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 201000007100 Pharyngitis Diseases 0.000 description 2
- 206010067171 Regurgitation Diseases 0.000 description 2
- 235000000336 Solanum dulcamara Nutrition 0.000 description 2
- 206010043458 Thirst Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 239000002221 antipyretic Substances 0.000 description 2
- 201000009361 ascariasis Diseases 0.000 description 2
- 210000003445 biliary tract Anatomy 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 210000000232 gallbladder Anatomy 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 235000003642 hunger Nutrition 0.000 description 2
- 201000001421 hyperglycemia Diseases 0.000 description 2
- 230000003451 hyperinsulinaemic effect Effects 0.000 description 2
- 201000008980 hyperinsulinism Diseases 0.000 description 2
- 210000003026 hypopharynx Anatomy 0.000 description 2
- 230000001976 improved effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000003907 kidney function Effects 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 201000003453 lung abscess Diseases 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 208000022530 polyphagia Diseases 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000001603 reducing effect Effects 0.000 description 2
- 206010040872 skin infection Diseases 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 230000004206 stomach function Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 210000004916 vomit Anatomy 0.000 description 2
- 208000016261 weight loss Diseases 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 241000244186 Ascaris Species 0.000 description 1
- 206010003591 Ataxia Diseases 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010006895 Cachexia Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 240000004528 Catalpa ovata Species 0.000 description 1
- 235000010005 Catalpa ovata Nutrition 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010010947 Coordination abnormal Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010012669 Diabetic hyperosmolar coma Diseases 0.000 description 1
- 208000032928 Dyslipidaemia Diseases 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108010061435 Enalapril Proteins 0.000 description 1
- 206010014759 Endometrial neoplasm Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- 206010018367 Glomerulonephritis chronic Diseases 0.000 description 1
- 108010023302 HDL Cholesterol Proteins 0.000 description 1
- 208000023661 Haematological disease Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010019799 Hepatitis viral Diseases 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020741 Hyperpyrexia Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 206010028836 Neck pain Diseases 0.000 description 1
- 208000001140 Night Blindness Diseases 0.000 description 1
- 206010033425 Pain in extremity Diseases 0.000 description 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
- 240000002834 Paulownia tomentosa Species 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 206010034568 Peripheral coldness Diseases 0.000 description 1
- 206010034960 Photophobia Diseases 0.000 description 1
- 235000014676 Phragmites communis Nutrition 0.000 description 1
- 206010062104 Renal mass Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 201000004239 Secondary hypertension Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 241000282894 Sus scrofa domesticus Species 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000009911 Urinary Calculi Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 206010047531 Visual acuity reduced Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 208000036981 active tuberculosis Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 229940127003 anti-diabetic drug Drugs 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 230000001166 anti-perspirative effect Effects 0.000 description 1
- 239000003472 antidiabetic agent Substances 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 206010007625 cardiogenic shock Diseases 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 208000016097 disease of metabolism Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 208000026500 emaciation Diseases 0.000 description 1
- GBXSMTUPTTWBMN-XIRDDKMYSA-N enalapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 GBXSMTUPTTWBMN-XIRDDKMYSA-N 0.000 description 1
- 229960000873 enalapril Drugs 0.000 description 1
- 201000003914 endometrial carcinoma Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 238000000556 factor analysis Methods 0.000 description 1
- 208000024756 faint Diseases 0.000 description 1
- 210000002468 fat body Anatomy 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 238000005242 forging Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000000745 gonadal hormone Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000016290 incoordination Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 231100001022 leukopenia Toxicity 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 description 1
- 229960003105 metformin Drugs 0.000 description 1
- 230000001617 migratory effect Effects 0.000 description 1
- 201000002266 mite infestation Diseases 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000003119 painkilling effect Effects 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 201000001514 prostate carcinoma Diseases 0.000 description 1
- 208000018299 prostration Diseases 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 201000001474 proteinuria Diseases 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000012109 statistical procedure Methods 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 230000008359 toxicosis Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 201000001862 viral hepatitis Diseases 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicinal composition for treating metabolic syndrome. The traditional Chinese medicinal composition consists of the following components: radix angelicae sinensis, radix notoginseng, ginseng, rhizoma alismatis, lotus leaves, dark plums, fiveleaf gynostemma herb, semen cassiae, platycodon root, liquorice root, fructus xanthii, bulbus allii macrostemi, cassia twig, radix paeoniae alba, radix salviae miltiorrhizae, rhizoma coptidis, fructus crataegi, herba houttuyniae, peach kernels, semen raphani, semen litchi, radix astragali, common dayflower herb, honeysuckle flowers, dandelion, mung beans, aloe, poria cocos, radix stephaniae tetrandrae, herba dianthi, lagenaria siceraria, radix curcumae, herba leonuri, fructus amomi, radix puerariae and folium lycii. The traditional Chinese medicinal composition disclosed by the invention, through the compatibility of the various medicines which complement each other, is effectively applicable to the dialectical treatment of the metabolic syndrome, and the traditional Chinese medicinal composition is capable of improving blood lipid level, relieving insulin resistance and obesity state, and the like. The traditional Chinese medicinal composition disclosed by the invention is convenient to prepare, low in side effect, high in safety and low in cost; and the traditional Chinese medicinal composition provides a technical basis for the research and development of medicines for treating integral metabolic syndrome and complications thereof.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to treat the Chinese medicine composition of metabolism syndrome.
Background technology
Metabolism syndrome refers to the pathological state of the material generation metabolism disorders such as the protein of human body, fat, carbohydrate,
It is a complex set of metabolism disorder disease group, is the risk factor causing diabetes cardiovascular and cerebrovascular disease.It has the following characteristics that
The most multiple metabolism disorder is rolled into one, metabolic arthritis, height glutinous including obesity, hyperglycemia, hypertension, dyslipidemia, high blood
Fatty liver incidence rate and hyperinsulinemia, these metabolism disorders are the pathologic basis of the heart, cerebrovascular disease and diabetes.
Visible diabetes are not isolated diseases, but one of ingredient of metabolism syndrome.2. there is common pathologic basis,
Think that at present their common cause is exactly the obesity insulin resistant that especially central obesity is caused and hyperinsulinemia more
Disease.3. multiple disease can be caused to increase, such as hypertension, coronary heart disease, apoplexy, even some cancer, including with gonadal hormone
Relevant breast carcinoma, carcinoma of endometrium, carcinoma of prostate, and the cancer of pancreas of digestive system, liver and gall cancer, colon cancer etc..④
There are common prevention and remedy measures, prevent and treat a kind of metabolism disorder, be also advantageous for the preventing and treating of other metabolism disorders.
At present, treatment metabolic syndrome many uses fat regulation medicine, antidiabetic drug, antihypertensive etc. are treated, but every kind of medicine can only pin
Some or certain two pathology links to metabolic syndrome.It is of a great variety that this results in patient medication, adds medicine not
Good reaction and untoward reaction each other, and add the financial burden of patient, it is unfavorable for long-term treatment.Chinese medicine has many targets
The feature of some pharmacological action, it is possible to simultaneously improve insulin resistant, abnormal carbohydrate metabolism, obesity, blood fat disorder etc., and to generation
Bad clinical consequences such as atherosclerosis, the diabetes etc. of thanking to syndrome are prevented and treated.It addition, the traditional Chinese medical science also has the side of taking
Just, side effect is little, and safety is high, cheap, it is simple to long-term taking and reduce the advantages such as patient economy burden.Though it is existing
Having treatment metabolism syndrome multi-medicament, including Chinese medicine, but for various reasons, its use and curative effect are the most unsatisfactory, because of
This, treatment metabolism syndrome medicine on improvement and innovate imperative.
Summary of the invention
It is an object of the invention to provide the Chinese medicine composition for the treatment of metabolism syndrome.It is above-mentioned that the mesh of the present invention also resides in offer
The preparation method and its usage of the Chinese medicine composition for the treatment of metabolism syndrome.
In order to solve above-mentioned technical problem, the technical solution used in the present invention is as follows: the Chinese medicine composition for the treatment of metabolism syndrome
Thing is made up of each raw material components of following parts by weight proportioning:
The Chinese medicine composition for the treatment of metabolism syndrome, is made up of each component of following parts by weight: Radix Angelicae Sinensis 1-15 part, three
Seven 1-10 parts, Radix Ginseng 1-8 part, Rhizoma Alismatis 1-10 part, Folium Nelumbinis 5-25 part, Fructus Mume 5-20 part, Herb Gynostemmae Pentaphylli 5-18 part,
Semen Cassiae 2-13 part, Radix Platycodonis 2-8 part, Radix Glycyrrhizae 5-20 part, Fructus Xanthii 3-18 part, Bulbus Allii Macrostemonis 5-25 part, Ramulus Cinnamomi 2-11
Part, Radix Paeoniae Alba 2-14 part, Radix Salviae Miltiorrhizae 3-10 part, Rhizoma Coptidis 1-10 part, Fructus Crataegi 4-25 part, Herba Houttuyniae 1-10 part, Semen Persicae 2-6
Part, Semen Raphani 1-6 part, Semen Litchi 2-17 part, Radix Astragali 1-11 part, Herba Commelinae 1-8 part, Flos Lonicerae 1-12 part, Pu
Herba Taraxaci 1-12 part, Semen phaseoli radiati 1-12 part, Aloe 1-13 part, Poria 4-12 part, Radix Stephaniae Tetrandrae 2-11 part, Herba Dianthi 1-10 part,
Calabash 2-15 part, Radix Curcumae 1-8 part, Herba Leonuri 2-16 part, Fructus Amomi 2-11 part, Radix Puerariae 2-11 part, Folium Lycii 2-25
Part.
Furthermore, preferred each component parts by weight proportioning is:
Radix Angelicae Sinensis 1-11 part, Radix Notoginseng 1-10 part, Radix Ginseng 1-8 part, Rhizoma Alismatis 1-10 part, Folium Nelumbinis 5-25 part, Fructus Mume 5-16
Part, Herb Gynostemmae Pentaphylli 5-15 part, Semen Cassiae 2-10 part, Radix Platycodonis 2-5 part, Radix Glycyrrhizae 5-15 part, Fructus Xanthii 3-15 part, Bulbus Allii Macrostemonis
5-16 part, Ramulus Cinnamomi 2-10 part, Radix Paeoniae Alba 2-14 part, Radix Salviae Miltiorrhizae 3-10 part, Rhizoma Coptidis 1-10 part, Fructus Crataegi 4-16 part, fish raw meat
Grass 1-10 part, Semen Persicae 2-6 part, Semen Raphani 1-4 part, Semen Litchi 2-15 part, Radix Astragali 1-10 part, Herba Commelinae 1-8 part,
Flos Lonicerae 1-12 part, Herba Taraxaci 1-12 part, Semen phaseoli radiati 1-12 part, Aloe 1-13 part, Poria 4-12 part, Radix Stephaniae Tetrandrae 2-9
Part, Herba Dianthi 1-10 part, calabash 2-15 part, Radix Curcumae 1-8 part, Herba Leonuri 2-16 part, Fructus Amomi 2-11 part, Radix Puerariae 2-10
Part, Folium Lycii 2-16 part.
Furthermore, each component parts by weight proportioning being more highly preferred to is:
Radix Angelicae Sinensis 3 parts, Radix Notoginseng 3 parts, Radix Ginseng 1 part, Rhizoma Alismatis 2 parts, 6 parts of Folium Nelumbinis, Fructus Mume 5 parts, Herb Gynostemmae Pentaphylli 5 parts,
Semen Cassiae 3 parts, Radix Platycodonis 4 parts, 6 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 5 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 3 parts, pellet
Join 3 parts, Rhizoma Coptidis 1 part, Fructus Crataegi 8 parts, Herba Houttuyniae 6 parts, 3 parts of Semen Persicae, Semen Raphani 1 part, Semen Litchi 6 parts, yellow
Stilbene 4 parts, Herba Commelinae 4 parts, Flos Lonicerae 6 parts, Herba Taraxaci 5 parts, 6 parts of Semen phaseoli radiati, Aloe 2 parts, 4 parts of Poria, anti-
Oneself 2 parts, Herba Dianthi 2 parts, 2 parts of calabash, Radix Curcumae 2 parts, Herba Leonuri 7 parts, Fructus Amomi 6 parts, Radix Puerariae 3 parts, Folium Lycii
7 parts.
Furthermore, each component parts by weight proportioning being more highly preferred to is:
Radix Angelicae Sinensis 2 parts, Radix Notoginseng 2 parts, Radix Ginseng 1 part, Rhizoma Alismatis 3 parts, 10 parts of Folium Nelumbinis, Fructus Mume 6 parts, Herb Gynostemmae Pentaphylli 6 parts,
Semen Cassiae 4 parts, Radix Platycodonis 2 parts, 7 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 7 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 5 parts, pellet
Join 3 parts, Rhizoma Coptidis 1 part, Fructus Crataegi 6 parts, Herba Houttuyniae 2 parts, 3 parts of Semen Persicae, Semen Raphani 2 parts, Semen Litchi 8 parts, yellow
Stilbene 2 parts, Herba Commelinae 2 parts, Flos Lonicerae 6 parts, Herba Taraxaci 4 parts, 3 parts of Semen phaseoli radiati, Aloe 5 parts, 4 parts of Poria, anti-
Oneself 3 parts, Herba Dianthi 4 parts, 6 parts of calabash, Radix Curcumae 7 parts, Herba Leonuri 9 parts, Fructus Amomi 3 parts, Radix Puerariae 4 parts, Folium Lycii
7 parts.
Medicine of the present invention can be prepared as acceptable decoction, capsule on any pharmaceutics according to the common process of this area
One in agent, pill, tablet, powder, oral liquid, granule.
It addition, present invention also offers the preparation method of the Chinese medicine composition of above-mentioned treatment metabolism syndrome, including following step
Rapid: by described crude drug boiling twice, add water 5-10 times amount for the first time, boils 1-5 hour；Second time adds water
4-8 times amount, boils 0.5-3 hour, collecting decoction, filters, and in 55 DEG C, filtrate is concentrated into proportion is 1.14-1.47,
Release concentrated solution, dilute, stand 24 hours, take supernatant and cross 300-400 mesh filter screen, concentrate, add appropriate tax
Shape agent, is spray dried to granule；It is distributed into pouch, obtains powder.
Other preferred dosage form of the present invention also can be prepared as follows method and make: by described crude drug boiling twice, the
Once add water 5-10 times amount, boils 1-5 hour；Add water 4-8 times amount for the second time, boils 0.5-3 hour, collecting decoction,
Filtering, in 55 DEG C, filtrate is concentrated into proportion is 1.14-1.47, releases concentrated solution, dilute, stands 24 hours,
Take supernatant and cross 300-400 mesh filter screen, concentrate, the most routinely preparation process be respectively prepared corresponding capsule, pill,
Tablet, powder, oral liquid or granule.
Present invention additionally comprises the Chinese medicine composition of described treatment metabolism syndrome or described Chinese medicine composition with pharmaceutically
The application in the pharmaceutical preparation of preparation treatment metabolism syndrome of the acceptable pharmaceutical carrier.
Present invention additionally comprises described Chinese medicine composition or described Chinese medicine composition and pharmaceutically acceptable pharmaceutical carrier
In preparation treatment abnormal carbohydrate metabolism, central obesity, hypertension, hyperlipemia or the medicine system of atheromatosis
Application in agent.
By technique scheme, the present invention has the advantage that and provides the benefit that: all medicine compatibilities of the present invention, benefits mutually
Evident, can be effectively used for dialectical treatment metabolism syndrome, improve blood lipid level, alleviate insulin resistant and fat state etc..
The present invention is easy to make, side effect is little, safety is high, cheap, entirety and complication for metabolism syndrome are controlled
The research and development treating medicine provides technical foundation.
Detailed description of the invention
The core that the application is claimed, with it is crucial that the compatibility of Chinese medicine composition, does not lies in dosage form, every this Chinese medicine of employing
Any dosage form that compositions is made, belongs to the scope that the present invention is claimed.Its raw material components comprised is: Radix Angelicae Sinensis,
Radix Notoginseng, Radix Ginseng, Rhizoma Alismatis, Folium Nelumbinis, Fructus Mume, Herb Gynostemmae Pentaphylli, Semen Cassiae, Radix Platycodonis, Radix Glycyrrhizae, Fructus Xanthii, Bulbus Allii Macrostemonis, Ramulus Cinnamomi,
The Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, Rhizoma Coptidis, Fructus Crataegi, Herba Houttuyniae, Semen Persicae, Semen Raphani, Semen Litchi, the Radix Astragali, Herba Commelinae, Flos Lonicerae,
Herba Taraxaci, Semen phaseoli radiati, Aloe, Poria, Radix Stephaniae Tetrandrae, Herba Dianthi, calabash, Radix Curcumae, Herba Leonuri, Fructus Amomi, Radix Puerariae, Folium Lycii.
Wherein, main component and effect of each Chinese medicinal components is described below respectively:
Radix Angelicae Sinensis: sweet in the mouth is pungent, temperature, can rise and can drop, the YIN aspect of YANG is nontoxic.Though there being upper purgation to divide, enrich blood then one.
Dong Yuan calls tail removing blood stasis person, by mistake.Enter the heart, spleen, liver three dirty.But its property is the most dynamic, then QI invigorating, the benefit entered in the Qi-tonifying drug entered
Blood medicine is then enriched blood, the ascending medicine entered then carries gas, the fall entered by medicine then by blood also.And with cold then tremble with fear, use it
Re Zere, without determining merit also.
Radix Notoginseng: nature and flavor: hardship sweet, micro-, temperature.Gui Jing: return liver, stomach warp.Function cures mainly: dissipating blood stasis stops blooding, subduing swelling and relieving pain.
For spitting blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.
Radix Ginseng: nature and flavor: hardship sweet, micro-is flat.Gui Jing: return spleen, lung, heart channel.Function cures mainly: strongly invigorating primordial QI, multiple arteries and veins
Gu de-, invigorating the spleen to benefit the lung, promotes the production of body fluid, calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung breathes with cough, and Tianjin is hindered
Thirsty, interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb；Heart failure, cardiogenic shock.
Rhizoma Alismatis: nature and flavor: sweet, cold.Gui Jing: return kidney, bladder warp.Function cures mainly: diuresis, clearing away damp-heat.For little
The most unfavorable, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria；Hyperlipidemia.
Folium Nelumbinis: nature and flavor: bitter is flat.Gui Jing: return liver, spleen, stomach warp.Function cures mainly: clearing away summer-heat, sending up the lucid YANG,
Cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy
The stasis of blood is stopped blooding.For multiple hemorrhage and puerperal blood faints.
Fructus Mume: nature and flavor: sour, puckery is flat.Gui Jing: return liver, spleen, lung, large intestine channel.Function cures mainly: astringe the lung, astringing intestine to stop diarrhea,
Promote the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic dysentery laxation, deficiency-heat quenches one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract.
Herb Gynostemmae Pentaphylli: nature and flavor: bitter in the mouth；Micro-sweet；Cool in nature.Gui Jing: return lung；Spleen；Kidney channel.Function cures mainly: heat clearing away；Mend
Empty；Removing toxic substances.Main body void is weak；Nephrasthenia emission；Leukopenia；Hyperlipemia；Viral hepatitis；Chronic gastrointestinal
Scorching；Chronic tracheitis.
Semen Cassiae: nature and flavor: sweet, bitter, salty, is slightly cold.Gui Jing: return liver, large intestine channel.Function cures mainly: clearing away heat to improve acuity of vision,
Loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, dizziness of having a headache, poor vision, constipation.
Radix Platycodonis: nature and flavor: bitter, pungent is flat.Gui Jing: return lung meridian.Function cures mainly: lung qi dispersing, and sore-throat relieving eliminates the phlegm, evacuation of pus.
For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Radix Glycyrrhizae: nature and flavor: sweet, flat.1. " herbal classic ": " sweet in the mouth is flat." 2. " not Lu ": " be nontoxic." 3. " book on Chinese herbal medicine
Spread out justice ": " micro-cool." 4. " pearl sac ": " is raw sweet, flat；Process sweet, temperature." return through: enter spleen, stomach, lung meridian.①
Materia Medica of Decoction: " enter sufficient cloudy, lunar, shaoyin channel of fainting." 2. " Thunder God concocts property of medicine solution ": " enters the heart, spleen two warp."
3. " explaining abstruseness of the canon of materia medica ": " enter spleen, stomach." 4. " book on Chinese herbal medicine is through solving ": " enters lung meridian, spleen meridian." function
Cure mainly: and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Process use, control weakness of the spleen and stomach, lack of appetite, loose stool of suffering from abdominal pain, overstrain
Heating, consumptive lung disease cough, cardiopalmus, infantile convulsion；Raw use, controls laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solve poison of drug and
Alimentary toxicosis.1. " herbal classic ": " main the five internal organs six mansion cold and heat pathogen, hard muscles and bones, long muscle, times power, incised wound swells, and solves
Poison." 2. " not Lu ": " warming the middle warmer and descending qi, stuffy sensation with restlessness is losed heart, and hinders dirty cough, quenches the thirst, qualcomm meridian, profit vim and vigour, solves hundred medicines
Poison."
Fructus Xanthii: nature and flavor: sweet, temperature, poisonous.1. " herbal classic ": " sweet in the mouth, temperature." 2. " not Lu ": " be bitter."③
" product remittance essence is wanted ": " bitter but sweet flavor, warm in nature, slightly poisonous." return through: enter lung, Liver Channel.1. " Thunder God concocts property of medicine solution ":
" enter lung meridian." 2. " beautiful Chinese catalpa medicine solution ": " enters liver channel of foot-Jueyin." 3. " book on Chinese herbal medicine is looked for the truth ": " enters liver, spleen." 4. " meeting
About cure mirror ": " enter liver, kidney two warp." function cures mainly: dissipate wind, pain relieving, damp eliminating, parasite killing.Control headche due to wind-cold, nasal sinusitis,
Toothache, anemofrigid-damp arthralgia, limb pain twin, mange, pruritus.
Bulbus Allii Macrostemonis: nature and flavor: pungent, bitter, temperature.Gui Jing: return lung, stomach, large intestine channel.Function cures mainly: activating YANG and eliminating stagnation, circulation of qi promoting
Intestinal stasis relieving.For thoracic obstruction pain, phlegm retention cough with asthma, let out weight after dysentery.
Ramulus Cinnamomi: nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, bladder warp.Function cures mainly: diaphoresis expelling pathogenic factors from muscles, Wen Tong
Passages through which vital energy circulates, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention,
Edema, cardiopalmus, renal mass.
The Radix Paeoniae Alba: nature and flavor: picric acid is cool.1. " herbal classic ": " bitter in the mouth is flat." 2. " WU Pu Bencao ": " paulownia monarch: sweet,
Nontoxic.Qi primary: salty.Li Shi: the Slight Cold.Thunder God: acid." 3. " not Lu ": " acid, flat is slightly cold, slightly poisonous." return through:
Enter liver, spleen channel.1. " product remittance essence is wanted ": " row hands is lunar, meridian of Foot-TAI YIN." 2. " Bencao Jingshu ": " brothers are lunar draws
Through medicine, enter liver, spleen blood system." function cures mainly: nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing receives antiperspirant.Control the chest and abdomen pain over the hypochondriac region,
Dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Radix Salviae Miltiorrhizae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, Liver Channel.Function cures mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clearly
Heart relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, vexed
Sleeplessness；Hepatosplenomegaly, angina pectoris.
Rhizoma Coptidis: nature and flavor: bitter, cold.Gui Jing: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing away is dry
Wet, eliminating fire and detoxication.For damp and hot feeling of fullness, vomit acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, vexed not
Sleeping, heat in blood tells nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle；External treatment eczema, eczema, auditory meatus is suppurated.Rhizoma Coptidis (processed with wine) is apt to
The clear part of the body cavity above the diaphragm housing the heart and lungs is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness
Vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomit acid regurgitation.
Fructus Crataegi: nature and flavor: sour, sweet, tepor.Gui Jing: return spleen, stomach, Liver Channel.Function cures mainly: promoting digestion and invigorating the stomach, circulation of qi promoting
Dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia is ached
Bitterly；Hyperlipemia.Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving effect strengthens.For meat stagnation, dysentery is not well.
Herba Houttuyniae: nature and flavor: pungent, is slightly cold.Gui Jing: return lung meridian.Function cures mainly: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, diuresis
Treating stranguria.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Semen Persicae: nature and flavor: bitter sweet is flat.1. " herbal classic ": " bitter in the mouth is flat." 2. " not Lu ": " be sweet, nontoxic."③
" a thousand pieces of gold dietetic therapy ": " bitter but sweet flavor is pungent, flat, nontoxic." return through: enter the heart, liver, large intestine channel.Function cures mainly: removing blood stasis
Clots absorbing, moisturizes laxation.Controlling amenorrhea, lump in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, blood is dry
Constipation.
Semen Raphani: nature and flavor: acrid in the mouth；Sweet；Property flat.Gui Jing: spleen；Stomach；Lung；Large intestine channel.Function cures mainly: helps digestion and leads
Stagnant；Lowering the adverse-rising QI to resolve phlegm.Main stagnation of QI due to dyspepsia；Distension and fullness in the abdomen；Diarrhoea；Weight after dysentery；Cough ant phlegm；QI rising in reverse order dyspnea with fullness of the chest.
Semen Litchi: the dry mature seed of sapindaceous plant Fructus Litchi Litchi chinensis Sonn..Summer harvesting ripe
Fruit, removes peel and meat aril, cleans, dries.Nature and flavor: sweet puckery, temperature.1. " detailed outline ": " sweet, temperature,
Puckery, nontoxic." 2. " medical center bun is wanted ": " is sweet puckery, and temperature is micro-salty." 3. " Guangxi Chinese medicinal herbal ": " sweet and slightly bitter taste is puckery, and property is put down,
Nontoxic." return through: enter liver, kidney channel.1. " detailed outline ": " enter the moon of fainting." 2. " Bencao Jingshu ": " enters liver, kidney." 3. " this
Grass brief points ": " enter lunar, the JUE YIN meridian of foot." function cures mainly: warming middle-JIAO, regulates the flow of vital energy, pain relieving.Control gastric abscess, colicky, woman
Female's pricking caused by the stagnation of QI and blood.1. control the long pain of trusted subordinate's gastral cavilty, touch originator repeatly repeatly: Semen Litchi one money, the Radix Aucklandiae eight points.For end.Often take one
Money, clear soup is taken after mixing with liquid.(Jing-Yue Complete Works litchi perfume (or spice) dissipate) 2. controls pained and small intestine-QI: Semen Litchi one piece.Forging sustainability, wine is adjusted
Clothes, (amplification on Canon of Materia Medica) 3. controls kidney greatly such as bucket: Fructus Foeniculi, Pericarpium Citri Reticulatae Viride (full person), Semen Litchi decile on oceangoing ship.File dissipates, and fries,
Go out fire-toxin, for end.Two money under wine, taking medicine three times daily.(Effective Formulas Tested by Physicians for Generations litchi core dissipates) is 4. controlled hernia TUI and is swollen: Semen Litchi
Four nineteens, Pericarpium Citri Reticulatae (the whitest) nine money, sulfur four money, for end, it is big that lake, face ball Semen phaseoli radiati bought by saline.When meeting pain, hollow wine
Take nine balls, take the most again, also control all pain due to disorder of QI.(" smooth celestial being all efficacious prescriptions " Yuhuan reflex is red) 5. controls pricking caused by the stagnation of QI and blood: Semen Litchi (burns
Sustainability) half two, Rhizoma Cyperi one or two.Upper for end.Often taking two money, salt wine send down.
The Radix Astragali: nature and flavor: sweet, temperature.Gui Jing: return lung, spleen channel.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus,
Expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, gas
Empty edema, carbuncle difficulty is burst, and bursts for a long time and does not holds back, and blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes.
Herba Commelinae: nature and flavor: sweet, light, cold.Gui Jing: return lung, stomach, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, profit
Water is subsided a swelling.For anemopyretic cold, hyperpyrexia, laryngopharynx swelling and pain, edema oliguria, the puckery pain of pyretic stranguria, carbuncle furunculosis.
Flos Lonicerae: nature and flavor: sweet, cold.Gui Jing: return lung, the heart, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, wind-heat dissipating.
For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Herba Taraxaci: nature and flavor: bitter sweet, cold.1. Tang Materia Medica: " sweet in the mouth, flat, nontoxic." 2. Li Gao: " micro-hardship, cold.
" 3. " book on Chinese herbal medicine is stated ": " is sweet, puts down and is slightly cold." 4. Guangzhou army " conventional Chinese herbal medicine handbook ": " is bitter sweet, cold." return through:
Enter liver, stomach warp.1. Li Gao: " meridian of Foot-SHAO YIN." 2. " Amplification on Materia Medica addendum ": " enters bright, the Taiyin channels of sun." function master
Control: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis,
Cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Semen phaseoli radiati: nature and flavor: sweet, cold.Gui Jing: enter the heart, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, relieves summer heat.For summer-heat
Excessive thirst, the disease such as sore carbuncle.Radix Aconiti Lateralis Preparata, Fructus Crotonis poison can be solved.
Aloe: nature and flavor: bitter, cold.Gui Jing: return liver, stomach, large intestine channel.Function cures mainly: removing heat from the liver, relieving constipation.For
Constipation, infantile malnutrition, infantile convulsion；External treatment exudative dermatitis.
Poria: nature and flavor: sweet, light is flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Function cures mainly: promoting diuresis to eliminate damp pathogen, strong
Spleen mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Radix Stephaniae Tetrandrae: nature and flavor: bitter, cold.Gui Jing: return bladder, lung meridian.Function cures mainly: inducing diuresis to remove edema, wind-expelling pain-stopping.With
In edema tinea pedis, dysuria, eczema sore, rheumatic arthralgia；Hypertension.
Herba Dianthi: nature and flavor: bitter；Cold in nature.Gui Jing: the heart；Liver；Small intestinal；Bladder warp.Function cures mainly: diuresis；The wettest
Heat；Promoting blood circulation to restore menstrual flow.Main urinary obstruction；Pyretic stranguria；Stranguria with blood；Stranguria caused by urinary stone；Amenorrhea；Conjunctival congestion and swelling pain；Carbuncle sore tumefacting virus；Eczema scabies
Itch.
Calabash: sweet in the mouth, light, cold in nature.The moon is also.Cold stomach, dynamic cold disease.Having cold disease to eat it, tripe abdomen aches, send out rheumatism in abdomen,
Accumulation of phlegm.Have winddamp phlegm food stagnation it, send rubella, pruritus, unsuitable polyphagia.Cure mainly antipyretic, relieving restlessness, lung moistening, treating stranguria,
Diuresis, polyphagia makes us vomiting and diarrhea foot pain.
Radix Curcumae: nature and flavor: pungent, bitter, cold.Gui Jing: return liver, the heart, lung meridian.Function cures mainly: regulating qi to disperse stagnation, and clear away heart-fire solution
Strongly fragrant, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy goes mad, jaundice dark coloured urine.
Herba Leonuri: nature and flavor: bitter, pungent, is slightly cold.Gui Jing: return liver, pericardium channel.Function cures mainly: promoting blood flow to regulate menstruation, diuresis
Detumescence.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria；Acute nephritis edema.
Fructus Amomi: nature and flavor: pungent, temperature.Gui Jing: return spleen, stomach, kidney channel.Function cures mainly: removing dampness is whetted the appetite, warming spleen and stopping diarrha,
Regulate the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Radix Puerariae: nature and flavor: sweet, pungent is cool.Gui Jing: return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash,
Yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels；High blood
Pressure neck pain.
Folium Lycii: there is antipyretic, the treatment curative effect such as diabetes, relieving cough and resolving phlegm, effect: the liver and the kidney tonifying, only promote the production of body fluid
Yearningly, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling.Control deficient fever, excessive thirst, conjunctival congestion dusk pain, nyctalopia of hiding from view, bleeding not during menses, pyretic toxicity
Skin ulcer swells.
Below by way of concrete preferred embodiment, the present invention is described in further detail, but the present invention is not limited in following
Embodiment.
Embodiment 1
Radix Angelicae Sinensis 3 parts, Radix Notoginseng 3 parts, Radix Ginseng 1 part, Rhizoma Alismatis 2 parts, 6 parts of Folium Nelumbinis, Fructus Mume 5 parts, Herb Gynostemmae Pentaphylli 5 parts,
Semen Cassiae 3 parts, Radix Platycodonis 4 parts, 6 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 5 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 3 parts, pellet
Join 3 parts, Rhizoma Coptidis 1 part, Fructus Crataegi 8 parts, Herba Houttuyniae 6 parts, 3 parts of Semen Persicae, Semen Raphani 1 part, Semen Litchi 6 parts, yellow
Stilbene 4 parts, Herba Commelinae 4 parts, Flos Lonicerae 6 parts, Herba Taraxaci 5 parts, 6 parts of Semen phaseoli radiati, Aloe 2 parts, 4 parts of Poria, anti-
Oneself 2 parts, Herba Dianthi 2 parts, 2 parts of calabash, Radix Curcumae 2 parts, Herba Leonuri 7 parts, Fructus Amomi 6 parts, Radix Puerariae 3 parts, Folium Lycii
7 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment metabolism syndrome, comprises the following steps: added water by described crude drug
Decocting twice, add water 5 amounts for the first time, when boiling 2；Add water 5 amounts, when boiling 2, collecting decoction for the second time, filters,
In 55 DEG C, filtrate is concentrated into proportion is 1.14, releases concentrated solution, dilute, stands 24 hours, take supernatant mistake
300-400 mesh filter screen, concentrates, adds appropriate excipient, be spray dried to granule；It is distributed into pouch, obtains powder.
Embodiment 2
Radix Angelicae Sinensis 2 parts, Radix Notoginseng 2 parts, Radix Ginseng 1 part, Rhizoma Alismatis 3 parts, 10 parts of Folium Nelumbinis, Fructus Mume 6 parts, Herb Gynostemmae Pentaphylli 6 parts,
Semen Cassiae 4 parts, Radix Platycodonis 2 parts, 7 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 7 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 5 parts, pellet
Join 3 parts, Rhizoma Coptidis 1 part, Fructus Crataegi 6 parts, Herba Houttuyniae 2 parts, 3 parts of Semen Persicae, Semen Raphani 2 parts, Semen Litchi 8 parts, yellow
Stilbene 2 parts, Herba Commelinae 2 parts, Flos Lonicerae 6 parts, Herba Taraxaci 4 parts, 3 parts of Semen phaseoli radiati, Aloe 5 parts, 4 parts of Poria, anti-
Oneself 3 parts, Herba Dianthi 4 parts, 6 parts of calabash, Radix Curcumae 7 parts, Herba Leonuri 9 parts, Fructus Amomi 3 parts, Radix Puerariae 4 parts, Folium Lycii
7 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment metabolism syndrome, comprises the following steps: added water by described crude drug
Decocting twice, add water 5 amounts for the first time, when boiling 2；Add water 4 amounts, when boiling 1, collecting decoction for the second time, filters,
In 55 DEG C, filtrate is concentrated into proportion is 1.47, releases concentrated solution, dilute, stands 24 hours, take supernatant mistake
300-400 mesh filter screen, concentrates, and preparation process makes corresponding capsule the most routinely.
Embodiment 3
Radix Angelicae Sinensis 2 parts, Radix Notoginseng 2 parts, Radix Ginseng 1 part, Rhizoma Alismatis 3 parts, 10 parts of Folium Nelumbinis, Fructus Mume 6 parts, Herb Gynostemmae Pentaphylli 6 parts,
Semen Cassiae 4 parts, Radix Platycodonis 2 parts, 7 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 7 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 5 parts, pellet
Join 3 parts, Rhizoma Coptidis 1 part, Fructus Crataegi 6 parts, Herba Houttuyniae 2 parts, 3 parts of Semen Persicae, Semen Raphani 2 parts, Semen Litchi 8 parts, yellow
Stilbene 2 parts, Herba Commelinae 2, Flos Lonicerae 6, Herba Taraxaci 3, Semen phaseoli radiati 2, Aloe 2, Poria 4, Radix Stephaniae Tetrandrae 2, Herba Dianthi 2, calabash
Reed 3, Radix Curcumae 2, Herba Leonuri 3, Fructus Amomi 2, Radix Puerariae 3, Folium Lycii 4.
The preparation method of the Chinese medicine composition of above-mentioned treatment metabolism syndrome, comprises the following steps: added water by described crude drug
Decocting twice, add water 5 amounts for the first time, when boiling 2；Add water 4 amounts, when boiling 1, collecting decoction for the second time, filters,
In 55 DEG C, filtrate is concentrated into proportion is 1.47, releases concentrated solution, dilute, stands 24 hours, take supernatant mistake
300-400 mesh filter screen, concentrates, and preparation process makes pill the most routinely.
Toxicity test
Taking West Germany rabbit 80, male and female half and half, body weight 2.0-3.0kg, divide two groups, often group 40, one of which is super large
Dosetest group, another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, gives
Prescription formula is that administration by gavage is administered, and every day, secondary, serve on 7 days, observes every day and is administered reaction, and result shows that two groups of rabbit live
Dynamic, diet normal, medicine is without bad toxic and side effects.
One, blood fat reducing effect experiment
Materials and methods
1.1 material: laboratory animal takes 3 week old ablactation male Wister rats, body weight 55 ± 10g.
1.2 animal packet and 70 rats of method are randomly divided into Normal group, high fat high salt (model) group, diformazan is double
Guanidine group, atorvastatin group, the present composition high, medium and low dosage group, totally 7 groups, every treated animal 10.Just
Often control animals gives normal diet, and other respectively organize rat all with high fat (49% Adeps Sus domestica) high salt (4% sodium chloride) feedstuff
Feeding, each group rat drinks normal saline, feeds 8 weeks continuously.And fill respectively in modelling each administration on same day group rat
Stomach gives Drug therapy, and once a day, wherein atorvastatin group gives atorvastatin 8mg/kg, and blood sugar lowering group gives
Metformin 670mg/kg, Chinese medicine low (TCM-H), in (TCM-M), high (TCM-L) dosage component do not give
Give and be equivalent to crude drug amount 2g/kg, 4g/kg, 8g/kg body weight present composition.Put to death animal fasted for one day prior and can't help water,
Experiment terminates, and abdominal vein takes blood, detects serum insulin, insulin resistance index.
1.3 statistical procedures the data obtaineds are analyzed through statistics software SPSS13.0.Each group data are all with ± s table
Show that multiple comparisons one factor analysis of variance between measurement data sample average compares between group and checks with t.P ＜ 0.05
For statistically significant.
2. experimental result
Result shows, compares with model group and atorvastatin group, and the present composition all can obviously reduce metabolism syndrome
Rat blood serum insulin level and insulin resistance index (P ＜ 0.05 or 0.01)
Table 1 present composition is on rats with metabolic syndrome serum insulin and the impact of insulin resistance index
| Packet | INS(mU/L) | HONA-IR |
| Normal group | 0.672±0.141※ | 1.75±0.352※ |
| Model group | 0.905±0.235※ | 2.65±0.472 |
| Metformin | 0.660±0.173※ | 1.93±0.287※ |
| Atorvastatin | 0.823±0.210 | 2.30±0.421 |
| TCM-H | 0.616±0.150※※⊿ | 1.87±0.349※※⊿ |
| TCM-M | 0.669±0.123※⊿ | 1.79±0.413※⊿ |
| TCM-L | 0.616±0.150※⊿ | 1.86±0.331※⊿ |
Compare with model group, * P < 0.05；**P<0.01.△ P < 0.05 is compared with atorvastatin group.Experiment shows,
Chinese medicine composition of the present invention has significant impact to rat blood serum insulin and insulin resistance index, can be effectively used for treatment
Metabolism syndrome, and try out through clinical practice, achieve very satisfied Advantageous Effects.
Two, the clinical observation of Drug therapy metabolism syndrome of the present invention
The medication combined fasting of the present invention observes 68 example Metabolic Syndrome Patients clinically, and result shows this medication combined taboo
Food has good therapeutic effect to overweight/obesity and associated metabolic disease.Hypoglycemia is had no during use
Reaction and other untoward reaction.
(1) diabetes branch of Chinese Medical Association (CSS) diagnostic criteria in 2004 is pressed in metabolic syndrome diagnostic criteria: tool
Standby following 3 or above person.(1) overweight and (or) fat: BMI >=25kg/m2；(2) blood fat disorder: on an empty stomach
Blood TG >=1.7mmol/L, and (or) fasting blood HDL-C man ＜ 0.9mmol/L or female ＜ 1.0mmol/L person,
(or) make a definite diagnosis blood fat disorder person；(3) hyperglycemia: FPG >=6.1mmol/L (110mg/dl) and (or) 2hPG >=
7.8mmol/L (140mg/dl), (or) person that is diagnosed as treating diabetes；(4) hypertension: SBP/DBP >=
140/90mmHg, and (or) it is diagnosed as hyperpietic.
(2) case inclusive criteria
1 diagnostic criteria meeting metabolic syndrome；Between 2 age 18-70 years.
(3) case exclusion standard
1 age is under-18s or the patient of more than 70 years old；2 have Diabetic Acute complications (bag in nearly 1 month
Include in diabetic Hypoglycemia, diabetic hyperosmolar coma, Diabetic ketosis and ketoacidosis, diabetes lactate acid
Poison, Diabetic Acute infect)；3 merge the infull patient of severe cardiac, Liver and kidney function；4 mental diseases fail partner；
5 pregnant or age of sucking and preparation gravid woman；6 noncooperationists (refer to coordinate fasting maybe can not take Chinese medicine by regulation
And the person of affecting the treatment)；7 malignant tumor and inpatient with haematological diseases；8 active tuberculosis patients；Bursting of 9 serious gastrorrhagias
Infections patient；101 diabetes mellitus types；112 patients with type Ⅰ DM control bad, need insulin injection patient；12 is primary
Property hypertension enalapril meleate control the best, secondary hypertension patient；13 researcheres are deemed unsuitable for into other of group
Situation.
(4) all patients of Therapeutic Method all sign Informed Consent Form before starting treatment, all on the basis maintaining former treatment
On, carry out fasting (strict diet control) and add this Chinese medicine, one month course for the treatment of.
(5) observation index
1 curative effect index body weight, waistline, blood pressure, blood fat, change of blood sugar.
2 safety indexes hypoglycemic incidence, hunger intensity and curative compliance, hepatic and renal function, routine blood test.
(6) Comprehensive Clinical the standard of curative effect evaluation
Effective: weight loss more than 3.5 kilograms after month, blood fat, blood glucose, blood pressure are obviously improved the most earlier above.
Effective: weight loss more than 2 kilograms after month, improve before the most relatively fasting of blood fat, blood glucose, blood pressure.
Invalid: not reach above standard person.
(7) result
1 body weight and waistline change
In 68 example overweight/obesity persons, male's weight average declines more than 6 kilograms；Women averagely decline 10 kilograms with
On；Women waistline declines inconspicuous, may be more with women waist and belly capsule meat, measures not accurate enough relevant.
2 Blood Lipid
| Project | Number | Before treatment | After treatment |
| TC(mmom/L) | 68 | 7.13±1.03 | 4.03±0.37 |
| HDL-c(mmom/L) | 68 | 0.87±0.19 | 1.32±0.29 |
| LDL-c(mmom/L) | 68 | 4.18±0.86 | 2.19±0.17 |
| TG(mmom/L) | 68 | 5.96±1.14 | 1.53±1.01 |
3 change of blood sugar
| Project | Number | Before treatment | After treatment |
| FBG(mmom/L) | 68 | 9.1±2.3 | 6.2±1.1 |
| P0.5hBG(mmom/L) | 68 | 13.9±4.9 | 9.6±2.1 |
| P2hBG(mmom/L) | 68 | 11.9±3.1 | 6.9±1.4 |
4 Evaluation of Synthetic Effect of Holistics
The medication combined fasting of the present invention observes 68 example Metabolic Syndrome Patients, the most effective 43 examples, effective 24 examples, nothing clinically
Imitate 1 example.
The medication combined fasting of the present invention has good therapeutic effect to metabolism syndrome, and without obvious adverse reaction；Permissible
The ability of patient resistance to hunger is greatly improved and accepts the compliance of diet control.
The above, be only presently preferred embodiments of the present invention, and the present invention not makees any pro forma restriction, therefore
Every without departing from technical solution of the present invention content, according to the technical spirit of the present invention above example is made any simply
Amendment, equivalent variations and modification, all still fall within the range of technical solution of the present invention.
Claims (9)
1. treat the Chinese medicine composition of metabolism syndrome, it is characterised in that: it is made up of each component of following parts by weight:
Radix Angelicae Sinensis 1-15 part, Radix Notoginseng 1-10 part, Radix Ginseng 1-8 part, Rhizoma Alismatis 1-10 part, Folium Nelumbinis 5-25 part, Fructus Mume 5-20 part,
Herb Gynostemmae Pentaphylli 5-18 part, Semen Cassiae 2-13 part, Radix Platycodonis 2-8 part, Radix Glycyrrhizae 5-20 part, Fructus Xanthii 3-18 part, Bulbus Allii Macrostemonis 5-25
Part, Ramulus Cinnamomi 2-11 part, Radix Paeoniae Alba 2-14 part, Radix Salviae Miltiorrhizae 3-10 part, Rhizoma Coptidis 1-10 part, Fructus Crataegi 4-25 part, Herba Houttuyniae 1-10
Part, Semen Persicae 2-6 part, Semen Raphani 1-6 part, Semen Litchi 2-17 part, Radix Astragali 1-11 part, Herba Commelinae 1-8 part, Flos Lonicerae
1-12 part, Herba Taraxaci 1-12 part, Semen phaseoli radiati 1-12 part, Aloe 1-13 part, Poria 4-12 part, Radix Stephaniae Tetrandrae 2-11 part, Qu
Wheat 1-10 part, calabash 2-15 part, Radix Curcumae 1-8 part, Herba Leonuri 2-16 part, Fructus Amomi 2-11 part, Radix Puerariae 2-11 part,
Folium Lycii 2-25 part.
The Chinese medicine composition for the treatment of metabolism syndrome the most according to claim 1, it is characterised in that: it is by following
Each component composition of parts by weight:
Radix Angelicae Sinensis 1-11 part, Radix Notoginseng 1-10 part, Radix Ginseng 1-8 part, Rhizoma Alismatis 1-10 part, Folium Nelumbinis 5-25 part, Fructus Mume 5-16
Part, Herb Gynostemmae Pentaphylli 5-15 part, Semen Cassiae 2-10 part, Radix Platycodonis 2-5 part, Radix Glycyrrhizae 5-15 part, Fructus Xanthii 3-15 part, Bulbus Allii Macrostemonis
5-16 part, Ramulus Cinnamomi 2-10 part, Radix Paeoniae Alba 2-14 part, Radix Salviae Miltiorrhizae 3-10 part, Rhizoma Coptidis 1-10 part, Fructus Crataegi 4-16 part, fish raw meat
Grass 1-10 part, Semen Persicae 2-6 part, Semen Raphani 1-4 part, Semen Litchi 2-15 part, Radix Astragali 1-10 part, Herba Commelinae 1-8 part,
Flos Lonicerae 1-12 part, Herba Taraxaci 1-12 part, Semen phaseoli radiati 1-12 part, Aloe 1-13 part, Poria 4-12 part, Radix Stephaniae Tetrandrae 2-9
Part, Herba Dianthi 1-10 part, calabash 2-15 part, Radix Curcumae 1-8 part, Herba Leonuri 2-16 part, Fructus Amomi 2-11 part, Radix Puerariae 2-10
Part, Folium Lycii 2-16 part.
The Chinese medicine composition for the treatment of metabolism syndrome the most according to claim 1, it is characterised in that: it is by following
Each component composition of parts by weight:
Radix Angelicae Sinensis 3 parts, Radix Notoginseng 3 parts, Radix Ginseng 1 part, Rhizoma Alismatis 2 parts, 6 parts of Folium Nelumbinis, Fructus Mume 5 parts, Herb Gynostemmae Pentaphylli 5 parts,
Semen Cassiae 3 parts, Radix Platycodonis 4 parts, 6 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 5 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 3 parts, pellet
Join 3 parts, Rhizoma Coptidis 1 part, Fructus Crataegi 8 parts, Herba Houttuyniae 6 parts, 3 parts of Semen Persicae, Semen Raphani 1 part, Semen Litchi 6 parts, yellow
Stilbene 4 parts, Herba Commelinae 4 parts, Flos Lonicerae 6 parts, Herba Taraxaci 5 parts, 6 parts of Semen phaseoli radiati, Aloe 2 parts, 4 parts of Poria, anti-
Oneself 2 parts, Herba Dianthi 2 parts, 2 parts of calabash, Radix Curcumae 2 parts, Herba Leonuri 7 parts, Fructus Amomi 6 parts, Radix Puerariae 3 parts, Folium Lycii
7 parts.
4. the Chinese medicine composition of the treatment metabolism syndrome according to any one of claim 1-3, it is characterised in that: when
Return 2 parts, Radix Notoginseng 2 parts, Radix Ginseng 1 part, Rhizoma Alismatis 3 parts, 10 parts of Folium Nelumbinis, Fructus Mume 6 parts, Herb Gynostemmae Pentaphylli 6 parts, Semen Cassiae
Son 4 parts, Radix Platycodonis 2 parts, 7 parts of Radix Glycyrrhizae, Fructus Xanthii 3 parts, Bulbus Allii Macrostemonis 7 parts, Ramulus Cinnamomi 3 parts, the Radix Paeoniae Alba 5 parts, Radix Salviae Miltiorrhizae 3
Part, Rhizoma Coptidis 1 part, Fructus Crataegi 6 parts, Herba Houttuyniae 2 parts, 3 parts of Semen Persicae, Semen Raphani 2 parts, Semen Litchi 8 parts, the Radix Astragali 2
Part, Herba Commelinae 2 parts, Flos Lonicerae 6 parts, Herba Taraxaci 4 parts, 3 parts of Semen phaseoli radiati, Aloe 5 parts, 4 parts of Poria, Radix Stephaniae Tetrandrae 3
Part, Herba Dianthi 4 parts, 6 parts of calabash, Radix Curcumae 7 parts, Herba Leonuri 9 parts, Fructus Amomi 3 parts, Radix Puerariae 4 parts, Folium Lycii 7 parts.
5. according to the Chinese medicine composition of the treatment metabolism syndrome according to any one of claim 1-4, it is characterised in that:
Dosage form is the one in decoction, capsule, pill, tablet, powder, oral liquid, granule.
6. according to the preparation method of the Chinese medicine composition treating metabolism syndrome according to any one of claim 1-5,
It is characterized in that: comprise the following steps: by described crude drug boiling twice, add water 5-10 times amount for the first time, boils
Boil 1-5 hour；Add water 4-8 times amount for the second time, boils 0.5-3 hour, collecting decoction, filters, by filtrate in 55 DEG C
Being concentrated into proportion is 1.14-1.47, releases concentrated solution, dilute, stands 24 hours, take supernatant and cross 300-400 mesh
Filter screen, concentrates, adds appropriate excipient, be spray dried to granule；It is distributed into pouch, obtains powder.
7. according to the preparation method of the Chinese medicine composition treating metabolism syndrome according to any one of claim 1-6,
It is characterized in that: comprise the following steps: by described crude drug boiling twice, add water 5-10 times amount for the first time, boils
Boil 1-5 hour；Add water 4-8 times amount for the second time, boils 0.5-3 hour, collecting decoction, filters, by filtrate in 55 DEG C
Being concentrated into proportion is 1.14-1.47, releases concentrated solution, dilute, stands 24 hours, take supernatant and cross 300-400 mesh
Filter screen, concentrates, and preparation process is respectively prepared corresponding capsule, pill, tablet, powder, oral liquid the most routinely
Or granule.
The Chinese medicine composition for the treatment of metabolism syndrome the most according to claim 1 or described Chinese medicine composition and medicine
Acceptable pharmaceutical carrier application in the pharmaceutical preparation of preparation treatment metabolism syndrome on.
Application the most according to claim 8, it is characterised in that described Chinese medicine composition or described Chinese drug-treated group
Compound and pharmaceutically acceptable pharmaceutical carrier are at preparation treatment abnormal carbohydrate metabolism, central obesity, hypertension, hyperlipemia
Application in the pharmaceutical preparation of disease or atheromatosis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610268253.6A CN105920514A (en) | 2016-04-27 | 2016-04-27 | Traditional Chinese medicinal composition for treating metabolic syndrome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610268253.6A CN105920514A (en) | 2016-04-27 | 2016-04-27 | Traditional Chinese medicinal composition for treating metabolic syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105920514A true CN105920514A (en) | 2016-09-07 |
Family
ID=56837504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610268253.6A Withdrawn CN105920514A (en) | 2016-04-27 | 2016-04-27 | Traditional Chinese medicinal composition for treating metabolic syndrome |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105920514A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184752A (en) * | 2017-06-07 | 2017-09-22 | 广西中医药大学第附属医院 | A kind of blood fat regulating capsule and preparation method thereof |
| RU2684524C1 (en) * | 2018-05-21 | 2019-04-09 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for prediction of developing metabolic syndrome in patients with chronic viral hepatitis c |
| EP3603657A4 (en) * | 2017-09-21 | 2020-05-06 | Corporation Ilwonbio | Composition containing amomum villosum extract for prevention, alleviation, or treatment of obesity |
| RU2727465C1 (en) * | 2019-07-15 | 2020-07-21 | Игорь Фёдорович Душкин | Method of restorative treatment of patients with metabolic syndrome at sanatorium-and-spa stage |
| CN111671817A (en) * | 2020-07-04 | 2020-09-18 | 刘巧凤 | A Chinese medicinal composition for treating thick blood lipid and its preparation method |
| CN115400168A (en) * | 2022-10-31 | 2022-11-29 | 云南中医药大学 | A Chinese medicinal composition |
| WO2024063239A1 (en) * | 2022-09-23 | 2024-03-28 | 주식회사 한국인삼공사 | Composition for preventing, improving, or treating metabolic diseases, comprising extracts of red ginseng, crataegi fructus, and cassia semen |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028900A (en) * | 2010-06-12 | 2011-04-27 | 中山大学附属第一医院 | Traditional Chinese medicine for treating metabolic syndrome and preparation method thereof |
| CN104288412A (en) * | 2014-11-07 | 2015-01-21 | 河南中医学院 | Traditional Chinese medicinal composition for treating metabolic syndrome |
-
2016
- 2016-04-27 CN CN201610268253.6A patent/CN105920514A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028900A (en) * | 2010-06-12 | 2011-04-27 | 中山大学附属第一医院 | Traditional Chinese medicine for treating metabolic syndrome and preparation method thereof |
| CN104288412A (en) * | 2014-11-07 | 2015-01-21 | 河南中医学院 | Traditional Chinese medicinal composition for treating metabolic syndrome |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184752A (en) * | 2017-06-07 | 2017-09-22 | 广西中医药大学第附属医院 | A kind of blood fat regulating capsule and preparation method thereof |
| EP3603657A4 (en) * | 2017-09-21 | 2020-05-06 | Corporation Ilwonbio | Composition containing amomum villosum extract for prevention, alleviation, or treatment of obesity |
| RU2684524C1 (en) * | 2018-05-21 | 2019-04-09 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method for prediction of developing metabolic syndrome in patients with chronic viral hepatitis c |
| RU2727465C1 (en) * | 2019-07-15 | 2020-07-21 | Игорь Фёдорович Душкин | Method of restorative treatment of patients with metabolic syndrome at sanatorium-and-spa stage |
| CN111671817A (en) * | 2020-07-04 | 2020-09-18 | 刘巧凤 | A Chinese medicinal composition for treating thick blood lipid and its preparation method |
| WO2024063239A1 (en) * | 2022-09-23 | 2024-03-28 | 주식회사 한국인삼공사 | Composition for preventing, improving, or treating metabolic diseases, comprising extracts of red ginseng, crataegi fructus, and cassia semen |
| CN115400168A (en) * | 2022-10-31 | 2022-11-29 | 云南中医药大学 | A Chinese medicinal composition |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101940740B (en) | Chinese medicinal preparation for treating anemia | |
| CN105920514A (en) | Traditional Chinese medicinal composition for treating metabolic syndrome | |
| CN101797326B (en) | Chinese materia medica preparation for treating borborygmus diarrhoea and preparation method thereof | |
| CN105749179A (en) | Traditional Chinese medicine composition for treating metabolic syndrome | |
| CN102755596B (en) | Traditional Chinese medicine for treating phlegm-dampness hyperplasia of mammary glands and preparation method thereof | |
| CN103736072B (en) | Medicine of a kind for the treatment of of allergic rhinitis and preparation method thereof | |
| CN106267120A (en) | A kind of Chinese medicine for treating rhinitis preparation and preparation method thereof | |
| CN109966462A (en) | A kind of herbal paste and preparation method thereof improving constitution | |
| CN105031517A (en) | Dendrobium officinale healthcare tea capable of reducing blood fat, blood sugar, and blood pressure and preparation method thereof | |
| CN105311581A (en) | Traditional Chinese medicine composition for preventing and treating hyperplasia of mammary glands and preparation method thereof | |
| CN102526498A (en) | Chinese medicine for eliminating toxic and side effects after nasopharyngeal carcinoma radiotherapy and preparation method and administration way thereof | |
| CN104189811A (en) | Traditional Chinese medicine composition for treating postpartum fainting and preparation method thereof | |
| CN103920034A (en) | Traditional Chinese medicine composition for alleviating side effects of chemotherapy of cancer patient and preparation method traditional Chinese medicine composition | |
| CN108619355A (en) | A kind of antitumor Chinese and preparation method thereof | |
| CN102698210A (en) | Traditional Chinese medicine capable of invigorating spleen and supplementing qi and treating gastroptosis | |
| CN104491718B (en) | Medicine for treating liver-depression and phlegm-stasis type mammary gland hyperplasia and preparation method | |
| CN103356901A (en) | Medicine for curing dampness-heat of spleen and stomach and preparation method thereof | |
| CN103041233A (en) | Pharmaceutical composition for treating infantile diarrhea and preparation method thereof | |
| CN106177542A (en) | The Chinese prescription of a kind of summer heat clearing toxin resolving and goods thereof | |
| CN104587300A (en) | Traditional Chinese medicine composition for treating acute leukemia and preparation method of traditional Chinese medicine composition | |
| CN108853340A (en) | A kind of Chinese medicine of nourishing the liver and kidney and preparation method thereof | |
| CN104189615B (en) | Traditional Chinese medicine preparation for treating metrorrhagia and metrostaxis, and preparation method of traditional Chinese medicine preparation | |
| CN103800744A (en) | Acne removing composition prepared from medicine-food homologous medicinal materials fully | |
| CN108671116A (en) | Herbal composite and its preparation for treating diabetes and instructions of taking | |
| CN103007145A (en) | Traditional Chinese medicine composition for treating children rotavirus enteritis and preparation method of composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20160907 |
|
| WW01 | Invention patent application withdrawn after publication |