CN103301341A - Traditional Chinese medicine composition of treating ischemic cerebral apoplexy - Google Patents
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention aims at providing a traditional Chinese medicine composition of treating ischemic cerebral apoplexy. The traditional Chinese medicine composition is prepared by repeated verification of a clinical test, and accords with the principle of the traditional Chinese medicine. According to the formula, natural plant and animal drugs are selected as materials; the combined effect of each traditional Chinese medicine is utilized to treat the ischemic cerebral apoplexy; the traditional Chinese medicine composition is free of chemical preparation, free of poison and harm to a human body; no matter how serious the state of an illness is, the drugs of the traditional Chinese medicine composition can be independently taken, and do not need to be combined with other drugs, so as to achieve the cure target. The pesticide effect can lastingly play a role; recurrence is not easily generated; the treatment effect is good. The pharmaceutical composition is characterized by comprising the components of fructus choerospondiatis, saffron crocus, globe amaranth flower, cinnamon, mulberry, semen cassia, olibanum, long-noded pit viper, cacumen biotae, succus bambusae, raphanus sativus, calculus bovis, centipede, rhizoma arisaematis, herba epimedii, tomentose glorybower branchlet and leaf, ginseng flower, lophatherum gracile, red ginseng, rosa chinensis, fruit of Chinese wolfberry, sesame and musk according to the ratio of the formula by manners of sorting, baking, crushing into fine powder, evenly mixing and packaging into capsules.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of Chinese medicine composition for the treatment of ischemia apoplexy.
Background technology
The blood of human body supply brain be the large blood vessel of 'go'gage to the little blood vessel of bore, finally arrive blood capillary.Therefore, when sclerosis occured the large tremulous pulse of bore, blood vessel wall can thicken in hardening, be covered with harden plaque and thrombi in the tube chamber, the existence of these things may not cause clinical symptoms at ordinary times and is easily ignored by the people, in case come off, will block more capillary vessel, cause cerebral infarction.
Ischemia apoplexy can be according to the morbidity weight just like the next stage:
Asymptomatic stage patient can without any neurological symptom and sign, only find to have the lacunar cerebral infarction when CT or magnetic resonance (MRI) inspection.Because these positions do not affect motion or sensation.This mainly is because due to micro-embolization comes off for transient ischemic attack (TIA).Clinical symptoms mainly comprises unexpected appearance one side limbs sensation or motor function transience obstacle, simple eye blindness or the aphasia of a property crossed.These symptoms can be recovered in 24 hours fully, and ordinary circumstance only continues a few minutes, and imaging examination is without focal lesion.At present, generally acknowledge that TIA is the tendency that the severe apoplexy occurs.If there is TIA, patient's probability that apoplexy occurs in 2 years is that the probability that occurs in 26%, 5 year is 40%.
Reversibility ischemic nerve injury (RIND) cerebral ischemia, focal neurological disorder can continue more than 24 hours, but recovered fully within a week, and imaging examination has focal lesion.
Apoplexy cerebral ischemia neurological disorder surpasses a week or apoplexy sequela (such as babble, a side limb movement disturbance etc.) is arranged recovery time, and corresponding neurological symptom, sign and Features are arranged.
The patient of apoplexy has been occured in some, also can improve brain blood circulation by above-mentioned processing, be beneficial to rehabilitation.The more important thing is the again generation of prevention apoplexy.
For causing one of human dead three major types disease apoplexy, the comprehensive treatment of employing has at present: 1, control blood pressure, cerebral; 2, volume expansion therapy; 3, medicament for expanding vascellum treatment; 4, thrombolytic therapy etc.Although these treatment measures can be played preferably effect, but its acute attack stage for apoplexy, also just control the deterioration development of mitigate the disease, although also have the therapeutic modalities such as some other logical bolt, operation, but risk is larger, and be subjected to disease time, the pharmacy of the conditions such as patient's age body constitution, and impracticable.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of ischemia apoplexy, form by the clinic tests and repeated verification configuration, the theory that meets Chinese medicine, it is raw material that we select natural animal-plant medicine, utilize the comprehensive function treatment ischemia apoplexy of the Chinese medicine of respectively distinguishing the flavor of, without chemicals, nontoxic to human body, no matter state of an illness weight all can be taken separately the present invention's medicine, need not unite use with other drug, can reach the healing purpose, and behind the cured substance taken of patient, the sustainable performance effect of drug effect, be difficult for recurrence, therapeutic effect is good.
A kind of Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that, is comprised of the raw material of following weight portion:
Fructus Choerospondiatis 20-30 part, Stigma Croci 20-30 part, Flos Gomphrenae 20-30 part, Cortex Cinnamomi 20-30 part, Fructus Mori 20-30 part, Semen Cassiae 20-30 part, Olibanum 20-30 part, Agkistrodon 10-20 part, Cacumen Platycladi 10-20 part, Succus Bambusae 10-20 part, Radix Raphani 10-20 part, Calculus Bovis 10-20 part, Scolopendra 30-40 part, Rhizoma Arisaematis 30-40 part, Herba Epimedii 30-40 part, Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 30-40 part, Flos Ginseng 1-10 part, Herba Lophatheri 1-10 part, Radix Ginseng Rubra 1-10 part, Flos Rosae Chinensis 1-10 part, Fructus Lycii 1-10 part, Semen Sesami 1-10 part, Moschus 0.1-0.9 part;
Preparation method process of the present invention is:
By formula proportion with the conventional sorting of all medicines after → dry → be crushed to 300-400 order fine powder → mix homogeneously → incapsulate.
A kind of Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that, is comprised of the raw material of following weight portion:
Fructus Choerospondiatis 22-28 part; Stigma Croci 22-28 part; Flos Gomphrenae 22-28 part; Cortex Cinnamomi 22-28 part; Fructus Mori 22-28 part; Semen Cassiae 22-28 part; Olibanum 22-28 part; Agkistrodon 12-18 part; Cacumen Platycladi 12-18 part; Succus Bambusae 12-18 part; Radix Raphani 12-18 part; Calculus Bovis 12-18 part; Scolopendra 32-38 part; Rhizoma Arisaematis 32-38 part; Herba Epimedii 32-38 part; Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 32-38 part; Flos Ginseng 2-8 part; Herba Lophatheri 2-8 part; Radix Ginseng Rubra 2-8 part; Flos Rosae Chinensis 2-8 part; Fructus Lycii 2-8 part; Semen Sesami 2-8 part; Moschus 0.2-0.8 part.
A kind of Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that, is comprised of the raw material of following weight portion:
25 parts of Fructus Choerospondiatis, 25 parts of Stigma Crocis, 25 parts of Flos Gomphrenaes, 25 parts of Cortex Cinnamomis, 25 parts in Fructus Mori, 25 parts of Semen Cassiaes, 25 parts of Olibanums, 15 parts of Agkistrodons, 15 parts of Cacumen Platycladis, 15 parts of Succus Bambusaes, 15 parts of Radix Raphanis, 15 parts of Calculus Boviss, 35 parts of Scolopendras, 35 parts of Rhizoma Arisaematiss, 35 parts of Herba Epimedii, 35 parts of Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels), 5 parts of Flos Ginseng, 5 parts of Herba Lophatheris, 5 parts of Radix Ginseng Rubra, 5 parts of Flos Rosae Chinensiss, 5 parts of Fructus Lycii, 5 parts of Semen Sesamis, 0.5 part in Moschus.
Soup potus preparation method of the present invention is specially:
Each component is pulverized respectively, be mixed in proportion, obtain mixture, add water to and flood mixture powder 3 ~ 5cm, soaked 1 ~ 2 hour, heating decocts, boil the rear slow fire of using, the rear decoction 2 ~ 4 hours of boiling for the first time leaches medicinal liquid, again add water in the filtering residue and flood mixture powder 3 ~ 5cm, heated and boiled is boiled the rear slow fire of using, the rear decoction 1 ~ 2 hour of boiling for the second time, filter, the medicinal liquid that merges twice filtration centrifugal 30 minutes ~ 1 hour, extracts supernatant, being concentrated into crude drug concentration is 1g/ml ~ 2g/ml, obtains the soup potus.
Injection preparation of the present invention is specially:
Each component is pulverized respectively, be mixed in proportion, obtain mixture, add water to and flood mixture powder 3 ~ 5cm, soaked 1 ~ 2 hour, heating decocts, boil the rear slow fire of using, the rear decoction 2 ~ 4 hours of boiling for the first time leaches medicinal liquid, again add water in the filtering residue and flood mixture powder 3 ~ 5cm, heated and boiled is boiled the rear slow fire of using, the rear decoction 1 ~ 2 hour of boiling for the second time filters, and merges the medicinal liquid of twice filtration, adding accounts for quality of liquid medicine 0.5% active carbon, keeps pH value 7.0, heats little boiling 15 minutes, cooling, filter, get the 500ml filtrate, inject water to 1000ml, packed, in 115 ℃ of sterilizations 30 minutes, cold preservation 48 hours namely got injection.
The present invention relates to pharmacology and the property of medicine of Chinese medicine:
Fructus Choerospondiatis:
[meridian distribution of property and flavor] is sweet, sour, and be flat.
[function] promoting flow of QI and blood nourishes heart, and calms the nerves, and resists myocardial ischemia the effects such as cardiac function protecting.Be used for qi depression to blood stasis, the thoracic obstruction is had a pain, shortness of breath and palpitation, irritability.
Stigma Croci:
[nature and flavor] sweet in the mouth, little suffering, property is flat; GUIXIN, Liver Channel.
[function cures mainly] has blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, the effect of removing pathogenic heat from blood and toxic substance from the body.Cure mainly menoxenia, dysmenorrhea, amenorrhea, disease that postpartum lochia can't go, enclosed mass pain in the abdomen, injury from falling down, melancholy painful abdominal mass is vexed, palpitation with fear, epidemic febrile disease is sent out speckle, measles.
Flos Gomphrenae:
[nature and flavor] are sweet, and are flat.
[function cures mainly] controls wind syndrome of head, ophthalmalgia, and asthma and cough, dysentery, pertussis, infantile convulsion, scrofula is stolen, skin infection.For chronic or asthmatic bronchitis, pertussis.
Cortex Cinnamomi:
[nature and flavor] extremely hot in nature, acrid in the mouth, sweet.
It is supporing yang that [function cures mainly] mends fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea, warming the meridian and promoting blood circulation.
Fructus Mori:
[nature and flavor] are sweet, are slightly cold; GUIXIN, liver, kidney channel.
[function cures mainly] controls hepatic and renal YIN deficiency, and send and take off, constipation, order is dark, tinnitus, former infections, articular instability.It is improved skin (comprising scalp) blood supply, the nutrition skin, makes the effect such as the delicate and black hair of skin, and can slow down aging.Fructus Mori is be healthy and strong U.S. face, antidotal good fruit and good medicine of middle-aged and elderly people.Normal food Fructus Mori can make eye bright the symptom that relieving eye strain is dry and astringent.Fructus Mori has immunologic enhancement.Fructus Mori has effect of gain to spleen, and reaction has potentiation to hemolytic, can prevent human body artery sclerosis, skeleton arthrosclerosis, enhances metabolism; Fructus Mori can promote the growth of erythrocyte, prevents leukopenia, and the diseases such as treatment diabetes, anemia, hypertension, hyperlipidemia, coronary heart disease, neurasthenia are had auxiliary curative effect.Fructus Mori has the effects such as promoting the production of body fluid to quench thirst, facilitating digestion, help defecation, and proper amount of edible can promote gastric secretion, stimulates enterokinesia and removes scorching.The traditional Chinese medical science thinks, Fructus Mori is sweet in flavor and cold in property, has the liver and the kidney tonifying, an effect such as the intestine moistening of promoting the production of body fluid, black hair make eye bright.
Semen Cassiae:
[nature and flavor] mildly bitter flavor is little sweet, and property is flat, little cold.
[function] returns liver, kidney, large intestine channel.Liver heat removing makes eye bright, relieving constipation.Be used for having a headache dizzy, conjunctival congestion is dim-sighted, constipation.1: the effect that reduces blood pressure; 2: the effect of resisting pathogenic microbes; 3: reduce the effect of serum cholesterol and triglyceride; 4: the diarrhea effect; 5: to uterine contraction and the effect of hastening parturition.
Olibanum: regulating QI, to invigorate blood circulation, pain relieving chases after poison.Antibiotic, the flatulence that restrains, dispels, promote that wound scabs, promotes cytoactive, sharp digestion, diuresis, calmness, benefit body, sharp uterus, controls wound.
Agkistrodon:
[nature and flavor] are sweet, salty, temperature; Poisonous.
[return through] returns Liver Channel.
[function] dispels the wind, collateral dredging, relieving convulsion.
[curing mainly] is used for rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies.
Cacumen Platycladi:
[nature and flavor] are cold in nature, bitter and puckery flavor.
[function cures mainly] removing heat from blood, hemostasis, wind-damp dispelling, loose toxic swelling.Control haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, cough, erysipelas, mumps is scalded." the SHENGCAO property of medicine is standby to be wanted ": " loose blood applies skin ulcer, beats deposited with slab sugar.Also control traumatic injury.It is contrary that " " medical center bun want ": " lets out lung, eliminating heart-fire, suppressing the hyperactive liver heat, the heat that purifies the blood minute.Diuresis, dissipating blood stasis are dispeled the wind in " " south of the Five Ridges gather medicinal herbs record ": " removing heat from blood circulation of qi promoting."
Succus Bambusae:
[meridian distribution of property and flavor] sweetness and bitterness is cold, return through: enter the heart, stomach warp, 1. " medicineization justice ": " enter lung, stomach two warps." 2. " book on Chinese herbal medicine is new again ": " enters the heart, liver, lung three warps."
The sliding expectorant of [function cures mainly] heat clearing away, relieving convulsion sharp key.Control middle wind-phlegm fan, lung-heat expectorant is stopped up, infantile convulsion, epilepsy, high fever excessive thirst, restlessness during pregnancy, tetanus.1. " not Lu ": " treat sudden and violent apoplexy migratory arthralgia, large heat be in the heart ended unhappy (have under the sentence of " detailed outline " end ' the recurrence caused by overexertion of quenching one's thirst ')." 2. " property of medicine opinion ": " controls apoplexy aphonia in silence." 3. supplement to the Herbal: " is yearningly vexed for a long time." 4. " detailed outline ": " controls the eclampsia gravidarum puerperal tetanus, separates the Extract Aconiti Radicis sucus poison." 5. essentials of Matea Medica: " pathogenic wind expelling pathogenic fire reducing is moisturized capable expectorant, the tonifying YIN that nourishes blood, sharp key tomorrow.Control the apoplexy locked mouth, the large heat of expectorant fan, puerperal tetanus is demented, and unhappiness is quenched one's thirst, spontaneous sweating due to deficientcy of blood.Liver-fire falls in " 6. " book on Chinese herbal medicine is new again ": " clearing away heart-fire, reduces phlegm and quenches the thirst, and toothache is controlled in analgesic relieving restlessness, bright eyes."
Radix Raphani:
Radix Raphani has another name called Radix Raphani, sieve clothes.
[Nature and flavor] Xin Gan, cold;
[return through
]Enter lung, stomach warp;
[function cures mainly] removing food stagnancy stagnates, the heat of reducing phlegm, the therapeutic method to keep the adverse QI flowing downwards, alleviating distention in middle-JIAO, detoxifcation.Control the food stagnation distension, phlegmatic cough aphonia is spitted blood, and epistaxis is quenched one's thirst, dysentery, migraine and general headache.
1. " not Lu ": " main sharp the five internal organs, beneficial rational diet gas." 2. Tang Materia Medica: " loose clothes and big gun boil to be taken, the large therapeutic method to keep the adverse QI flowing downwards, and rapid digestion of food removes accumulation of phlegm in the hypochondrium; Give birth to and smash the juice clothes, main quenching one's thirst."
3. the Meng numerous: " bad odor in the five internal organs except the five internal organs apoplexy, is practiced in very sharp joint."
4. " four tones of standard Chinese pronunciation book on Chinese herbal medicine ": " ordinary person surfeits, and gives birth to and chews just disappearing of pharynx, the also main lung haematemesis of coughing."
5. " feeding habits book on Chinese herbal medicine ": " sector-style gas, steam uncharms." " flower: make eye bright."
6. " Japan hanako materia medica ": " energy stopping coughing and removing phlegm; Controlling consumptive lung disease spits blood; Warming middle-JIAO, tonifying for the deficiency control the thin cough of labor, and Carnis caprae seu ovis, Carassius auratus is cooked it."
7. " daily book on Chinese herbal medicine ": " the chest stuffiness relieving diaphragm, sharp defecation.Prepared food it, rapid digestion of food reduces phlegm; Give birth to and eat it, alleviating distention in middle-JIAO quenches the thirst."
8. Wang Ying " food book on Chinese herbal medicine ": " give birth to and smash clothes, control fasting dysentery."
9. " book on Chinese herbal medicine can be compiled ": " kill fishy smell, control bean curd long-pending."
10. " detailed outline ": " main acid regurgitation, eliminate indigestion stagnates, alcoholic intoxication, dissipating blood stasis blood, very effect.The end clothes are controlled five types of stranguria; The ball clothes are controlled nebulousurine; Fry in shallow oil soup foot bath gas; Drink juice is controled the inferior dysentery and aphonia, and sootiness is wanted dead; Give birth to smash be coated with beat pounce on, burn."
⑾ " book on Chinese herbal medicine is looked for the truth ": " separate the Radix Aconiti Lateralis Preparata poison."
⑿ " occupying the diet spectrum with breath ": " control the cough with aphonia, all diseases of throat; Separate carbon monoxide poisoning, Fructus Solani melongenae poison.Ripe person's therapeutic method to keep the adverse QI flowing downwards and in, spleen reinforcing fortune food, born fluid is driven wind and cold, foul leukorrhea, damp fetal cultivation blood."
Calculus Bovis:
[nature and flavor with return through] are sweet, cold.GUIXIN, Liver Channel.
[function with cure mainly] clears away heart-fire, and eliminating phlegm is had one's ideas straightened out, cool liver, endogenous wind stopping, detoxifcation.Be used for the calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.
Scolopendra:
[meridian distribution of property and flavor] acrid in the mouth, temperature; Poisonous; Return Liver Channel.
[function cures mainly] endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Rhizoma Arisaematis:
[meridian distribution of property and flavor] is bitter, hot, temperature; Poisonous.Return lung, liver, spleen channel.
[function cures mainly] drying dampness to eliminate phlegm is expellingged wind and relieving convulsion mass dissipating and swelling eliminating.Be used for the pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Give birth to and use external treatment carbuncle, snake bite and insect sting.
Herba Epimedii:
[nature and flavor] are hot, cold, nontoxic.
Expelling wind and removing dampness is invigorated blood circulation in [function] tonifying YANG.
[curing mainly] be caused by liver and kidney deficiency 1., can not replenishing vital QI with drugs of warm nature, and QI-blood circulation is obstructed, and wet three heresies of wind and cold are taken advantage of the limbs joint pain due to attacking, migratory pain, joint joint stuffiness.2. the waist that thanks to causes of insufficiency of kidney-YANG is ached the lower limb weakness.3. the extremity of apoplexy sequela appearance are unsuccessful, skin numbness.
Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels):
[return through] liver; Kidney channel
[effect] dispelling wind and removing obstruction in the collateral; " middle traditional Chinese medicines are planted will ": control Pe1lionia tsoongii (Merr.) Merr.; Control poliomyelitis.
The Flos Ginseng:
[nature and flavor]: bitterness Hui Tian has the hot sweet taste of Radix Ginseng.
[function]: replenish human body vigour, regain one's strength, strengthen body immunity.
Herba Lophatheri:
[meridian distribution of property and flavor] is sweet, light, and be cold.GUIXIN, stomach, small intestine meridian.
[function cures mainly] clearing heat and relieving fidgetness, diuresis.Be used for the calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
Radix Ginseng Rubra:
[meridian distribution of property and flavor] sweet, little hardship, temperature is returned spleen, lung, heart channel;
[function cures mainly] strongly invigorating primordial QI, multiple arteries and veins takes off nourishing qi to stop admittedly.Be used for weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis; Heart failure, cardiogenic shock.
Flos Rosae Chinensis:
[meridian distribution of property and flavor] sweet in the mouth, warm in nature enters Liver Channel.
[function cures mainly] has the effect of promoting blood flow to regulate menstruation, subduing swelling and detoxicating.Because blood stasis dispelling, circulation of qi promoting, the analgesic effect of Flos Rosae Chinensis are obvious, therefore often be used to treat the diseases such as menoxenia, dysmenorrhea, amenorrhea appears in the women or menstruation is thin, color is light and the amount less, lower abdominal pain, have the smooth and constipation due to dry stool of spirit etc. concurrently, or above-mentioned symptom appears in menstrual phase, spring soup therapeutic effect is good with winning.
Fructus Lycii:
[nature and flavor] are sweet, and are flat, enter liver, stomach two warps, doublely enter lung meridian;
[function cures mainly] the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.Cure mainly: control apoplexy dizzy, asthenia is allly seen blood disorder, cough blood, flaccidity, faint, contraction, the miasma that disappears is hindered dryly, passes out semen reddish and whitish turbid urine, beriberi, the arthroncus of knee.
Semen Sesami:
Medicine is through record
Shennong's Herbal says, Semen Sesami cures mainly that " damaging the spleen and stomach is empty wins, and mends in five, physical strength profiting, longue meat, life essence-filling, marrow-benefitting.”
" the Master of Preserving Simplicity ": anti-rheumatism, mend old and feeble.
Compendium of Material Medica: linum is got oil, wins with Bai Zhewei, takes take black person as good.
" Bencao Congxin ": the intestinal that makes us of linum clothes is slided, and vital essence is not consolidated the person and also should do not eaten.
" book on Chinese herbal medicine is looked for the truth ": instability of kidney-QI and see the loose stool, sexual impotence, essence is sliding, and leucorrhea is all avoided usefulness.
Health preserving in ancient times scholar TAO Hong-Jing was once said: among eight paddy, only this be good, celestial family do the meal bait it, the paddy of breaking is long-living.
At ancient Chinese, Semen Sesami always is regarded as life lengthening food, and Song dynasty famous poet Soviet Union and Eastern Europe also thinks on the slope, and Semen Sesami can be kept fit body, and defying age steams linum with nine, and with the peeling Poria, entering less whitish honey is wheaten food, and with the passing of time strength does not wane, and all kinds of diseases and ailments are from going, and this is long-living gist.
Dietary function
Semen Sesami sweet in the mouth, property are put down, and enter liver, kidney, lung, spleen channel.
Enrich blood make eye bright, dispel the wind intestine moistening, the lactogenesis that promotes the production of body fluid, the liver benefiting hair care, keep fit body, the effect of defying age.
Can be used for treating that physical weakness, dizziness and tinnitus, hypertension, hyperlipidemia, cough, physical weakness, early whitening of hair, anemia are sallow, deficiency of body fluid, constipation due to dry stool, breast less, the disease such as hematuria.
It is deficient that [purposes] is used for Liver and kidney, asthenia of essence and blood, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, myasthenia of limbs; Puerperal blood deficiency, hypogalactia; Blood deficiency and depleted fluid, dryness of the intestine constipation etc.
Moschus:
[meridian distribution of property and flavor] acrid in the mouth, temperature.GUIXIN, spleen channel.
[function cures mainly] refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.Be used for the calentura coma, the apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, the attacked by pestiferous factors stupor, amenorrhea ， WEIJIA, the difficult labour stillborn fetus, trusted subordinate's sudden pain, the carbuncle scrofula, laryngopharynx swelling and pain falls and pounces on the pain of injury, and arthralgia pain is numb.
The specific embodiment:
Embodiment 1, prescription:
Fructus Choerospondiatis 20g, Stigma Croci 20, Flos Gomphrenae 20g, Cortex Cinnamomi 20g, Fructus Mori 20g, Semen Cassiae 20g, Olibanum 20g, Agkistrodon 10g, Cacumen Platycladi 10g, Succus Bambusae 10g, Radix Raphani 10g, Calculus Bovis 10g, Scolopendra 30g, Rhizoma Arisaematis 30g, Herba Epimedii 30g, Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 30g, Flos Ginseng 1g, Herba Lophatheri 1g, Radix Ginseng Rubra 1g, Flos Rosae Chinensis 1g, Fructus Lycii 1g, Semen Sesami 1g, Moschus 0.1g;
Preparation method process of the present invention is:
By formula proportion with the conventional sorting of all medicines after → dry → be crushed to 300-400 order fine powder → mix homogeneously → incapsulate.
Instructions of taking: each 2, every day twice, every 0.25g, warm water takes.
Embodiment 2, prescription:
Fructus Choerospondiatis 22g, Stigma Croci 22g, Flos Gomphrenae 22g, Cortex Cinnamomi 22g, Fructus Mori 22g, Semen Cassiae 22g, Olibanum 22g, Agkistrodon 12g, Cacumen Platycladi 12g, Succus Bambusae 12g, Radix Raphani 12g, Calculus Bovis 12g, Scolopendra 32g, Rhizoma Arisaematis 32g, Herba Epimedii 32g, Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 32g, Flos Ginseng 2g, Herba Lophatheri 2g, Radix Ginseng Rubra 2g, Flos Rosae Chinensis 2g, Fructus Lycii 2g, Semen Sesami 2g, Moschus 0.2g.
Preparation method is identical with embodiment 1.
Embodiment 3, prescription:
Fructus Choerospondiatis 25g, Stigma Croci 25g, Flos Gomphrenae 25g, Cortex Cinnamomi 25g, Fructus Mori 25g, Semen Cassiae 25g, Olibanum 25g, Agkistrodon 15g, Cacumen Platycladi 15g, Succus Bambusae 15g, Radix Raphani 15g, Calculus Bovis 15g, Scolopendra 35g, Rhizoma Arisaematis 35g, Herba Epimedii 35g, Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 35g, Flos Ginseng 5g, Herba Lophatheri 5g, Radix Ginseng Rubra 5g, Flos Rosae Chinensis 5g, Fructus Lycii 5g, Semen Sesami 5g, Moschus 0.5g.
Preparation method is identical with embodiment 1.
Embodiment 4, prescription:
Fructus Choerospondiatis 28g, Stigma Croci 28g, Flos Gomphrenae 28g, Cortex Cinnamomi 28g, Fructus Mori 28g, Semen Cassiae 28g, Olibanum 28g, Agkistrodon 18g, Cacumen Platycladi 18g, Succus Bambusae 18g, Radix Raphani 18g, Calculus Bovis 18g, Scolopendra 38g, Rhizoma Arisaematis 38g, Herba Epimedii 38g, Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 38g, Flos Ginseng 8g, Herba Lophatheri 8g, Radix Ginseng Rubra 8g, Flos Rosae Chinensis 8g, Fructus Lycii 8g, Semen Sesami 8g, Moschus 0.8g.
Soup potus preparation method is specially:
Each component is pulverized respectively, be mixed in proportion, obtain mixture, add water to and flood mixture powder 3 ~ 5cm, soaked 1 ~ 2 hour, heating decocts, boil the rear slow fire of using, the rear decoction 2 ~ 4 hours of boiling for the first time leaches medicinal liquid, again add water in the filtering residue and flood mixture powder 3 ~ 5cm, heated and boiled is boiled the rear slow fire of using, the rear decoction 1 ~ 2 hour of boiling for the second time, filter, the medicinal liquid that merges twice filtration centrifugal 30 minutes ~ 1 hour, extracts supernatant, being concentrated into crude drug concentration is 1g/ml ~ 2g/ml, obtains the soup potus.
Instructions of taking: every day twice, each one little bowl, warm taking.
Embodiment 5, prescription:
Fructus Choerospondiatis 30g, Stigma Croci 30g, Flos Gomphrenae 30g, Cortex Cinnamomi 30g, Fructus Mori 30g, Semen Cassiae 30g, Olibanum 30g, Agkistrodon 20g, Cacumen Platycladi 20g, Succus Bambusae 20g, Radix Raphani 20g, Calculus Bovis 20g, Scolopendra 40g, Rhizoma Arisaematis 40g, Herba Epimedii 40g, Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 40g, Flos Ginseng 10g, Herba Lophatheri 10g, Radix Ginseng Rubra 10g, Flos Rosae Chinensis 10g, Fructus Lycii 10g, Semen Sesami 10g, Moschus 0.9g;
Injection preparation of the present invention is specially:
Each component is pulverized respectively, be mixed in proportion, obtain mixture, add water to and flood mixture powder 3 ~ 5cm, soaked 1 ~ 2 hour, heating decocts, boil the rear slow fire of using, the rear decoction 2 ~ 4 hours of boiling for the first time leaches medicinal liquid, again add water in the filtering residue and flood mixture powder 3 ~ 5cm, heated and boiled is boiled the rear slow fire of using, the rear decoction 1 ~ 2 hour of boiling for the second time filters, and merges the medicinal liquid of twice filtration, adding accounts for quality of liquid medicine 0.5% active carbon, keeps pH value 7.0, heats little boiling 15 minutes, cooling, filter, get the 500ml filtrate, inject water to 1000ml, packed, in 115 ℃ of sterilizations 30 minutes, cold preservation 48 hours namely got injection.
The pharmacology pharmacodynamic experiment:
1, acute toxicity test
The application mice carries out acute toxicity testing and shows: mice oral administration gavage Chinese medicine preparation of the present invention, under 488.8g crude drug/kg dosage, the light activity minimizing appears in mice after the administration, recover normal about 1 hour, Continuous Observation is 7 days after the administration, none animal dead, its overall health of patients, diet, to take the photograph water, urine and body weight gain all normal, and experimental result shows: the maximum dosage-feeding of mice oral administration gavage Traditional Chinese medicine preparation capsule agent of the present invention is 488.8g crude drug/kg/d (LD 50＞488.8g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.1g crude drug/kg/d; Press weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 4888 times of clinical patient.Point out this medicine acute toxicity low, clinical drug safety.
2, long term toxicity test
Select the SD rat, give variable concentrations (18.0,6.0, the Chinese medicine preparation of the present invention of 2.0g crude drug/kg), every day gavage once, continuous 90 days, 24 hours each groups are lived and are killed 1/2 animal (male and female half and half) after the last administration, live extremely after all the other 1/2 animals continuation observed for 2 weeks.Duration of test is observed outward appearance, general behavior, food ration, the body weight change of animal, after the administration 90 days and carry out hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) in 2 weeks of drug withdrawal and the index checkings such as blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology.Result of the test shows: preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight gain all change without unusual; Three dosage groups and matched group hematological examination, blood biochemical are learned, the urine biochemical analysis is all in normal range, between group without significant difference; Each is organized the main organs histopathological examination and shows no obvious abnormalities.The These parameters drug withdrawal also has no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test Chinese medicine preparation of the present invention high, medium and low three dosage (18.0,6.0, the 2.0g crude drug/kg) administration in continuous 90 days has no significant effect rat, without clear and definite toxicity target organ and sensitive indicator, the convalescent period observation also has no the retardance toxic reaction, points out the dosage safety of Chinese medicine preparation clinical practice of the present invention higher.
3, animal local excitation test:
The allergic reaction on guinea pigs of preparation of the present invention and Rat-rectum medication irritation test.The result shows: skin anaphylactic test, high dose group 0.8g (medicated powder)/kg, low dose group 0.1g (medicated powder)/kg, be equivalent to respectively to intend 20 times, 2.5 times of clinical people's consumption [0.04g (medicated powder)/kg], through the skin administration, be showed no animal and produce allergy; Rectal application irritation test high dose group 5.0g (medicated powder)/kg, low dose group 3.2g (medicated powder)/kg, be equivalent to respectively to intend 125,80 times of clinical people's consumption, observe mucous membrane of rectum all without phenomenons such as hyperemia, edema in setting time, histopathologic examination and blank group be no significant difference relatively, have no and obvious irritative response occurs, every group of its overall health of patients of Some Animals of retaining, body weight, breathing, circulation, central nervous system and extremity activity etc., all Non Apparent Abnormality reactions.
The observation of curative effect for the treatment of ischemia apoplexy
Ischemia apoplexy, we adopted homemade traditional Chinese drug prescription treatment case 1000 many cases in 2000-2012 according to clinical statistics, obtained good result, now were summarized as follows.
Diagnostic criteria:
Suddenly faint with the patient, syncope, facial hemiparalysis occurs together, dysphonia, hemiplegia or faint and hemiplegia occurs suddenly or partially body is unable, the symptoms such as hemidysesthesia, aphasia, monocular vision obstacle, engage brain CT examination feature and show, low-density shadow both can be made a definite diagnosis as pathological changes.
Typical clinical case inclusion criteria:
Inclusion criteria: have typical clinical manifestation, meet diagnostic criteria.
MethodsThe cases enrolled 600 examples, wherein male's 380 examples. women's 220 examples.
Efficacy determination: adopt 4 grade standards
Curative effect judging standard (pressing limbs changes):
1, invalid: show as and collapse from physical exhaustion, limbs do not have motor function.
2, effective: limb function begins to recover, and occurs faint voluntary movement, and muscle spasm is rudimentary not with motion with some.
3, produce effects: muscle spasm begins to alleviate, and study was had any problem when some were initial than compound movement, has then then become easily or can learn the more difficult motion of being responsible for.
4, recovery from illness: muscle spasm disappears, and the various motions in each joint can both be carried out, and the motor coordination function approaches normal.
Clinical statistics is summarized as follows:
Recovery from illness clinical improvements rate 〉=95%; Produce effects clinical improvements rate＜95%, 〉=60%;
Effective clinical improvement rate＜60%, 〉=20%; Invalid clinical improvements rate＜20%.
Claims (6)
1. a Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that, is comprised of the raw material of following weight portion:
Fructus Choerospondiatis 20-30 part; Stigma Croci 20-30 part; Flos Gomphrenae 20-30 part; Cortex Cinnamomi 20-30 part; Fructus Mori 20-30 part; Semen Cassiae 20-30 part; Olibanum 20-30 part; Agkistrodon 10-20 part; Cacumen Platycladi 10-20 part; Succus Bambusae 10-20 part; Radix Raphani 10-20 part; Calculus Bovis 10-20 part; Scolopendra 30-40 part; Rhizoma Arisaematis 30-40 part; Herba Epimedii 30-40 part; Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 30-40 part; Flos Ginseng 1-10 part; Herba Lophatheri 1-10 part; Radix Ginseng Rubra 1-10 part; Flos Rosae Chinensis 1-10 part; Fructus Lycii 1-10 part; Semen Sesami 1-10 part; Moschus 0.1-0.9 part.
2. a kind of Chinese medicine composition for the treatment of ischemia apoplexy according to claim 1 is characterized in that, is comprised of the raw material of following weight portion:
Fructus Choerospondiatis 22-28 part; Stigma Croci 22-28 part; Flos Gomphrenae 22-28 part; Cortex Cinnamomi 22-28 part; Fructus Mori 22-28 part; Semen Cassiae 22-28 part; Olibanum 22-28 part; Agkistrodon 12-18 part; Cacumen Platycladi 12-18 part; Succus Bambusae 12-18 part; Radix Raphani 12-18 part; Calculus Bovis 12-18 part; Scolopendra 32-38 part; Rhizoma Arisaematis 32-38 part; Herba Epimedii 32-38 part; Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels) 32-38 part; Flos Ginseng 2-8 part; Herba Lophatheri 2-8 part; Radix Ginseng Rubra 2-8 part; Flos Rosae Chinensis 2-8 part; Fructus Lycii 2-8 part; Semen Sesami 2-8 part; Moschus 0.2-0.8 part.
3. a kind of Chinese medicine composition for the treatment of ischemia apoplexy according to claim 1 is characterized in that, is comprised of the raw material of following weight portion:
25 parts of Fructus Choerospondiatis, 25 parts of Stigma Crocis, 25 parts of Flos Gomphrenaes, 25 parts of Cortex Cinnamomis, 25 parts in Fructus Mori, 25 parts of Semen Cassiaes, 25 parts of Olibanums, 15 parts of Agkistrodons, 15 parts of Cacumen Platycladis, 15 parts of Succus Bambusaes, 15 parts of Radix Raphanis, 15 parts of Calculus Boviss, 35 parts of Scolopendras, 35 parts of Rhizoma Arisaematiss, 35 parts of Herba Epimedii, 35 parts of Cacumen et folium clerodendri mandarinori (Clerodendron mandarinorum Diels), 5 parts of Flos Ginseng, 5 parts of Herba Lophatheris, 5 parts of Radix Ginseng Rubra, 5 parts of Flos Rosae Chinensiss, 5 parts of Fructus Lycii, 5 parts of Semen Sesamis, 0.5 part in Moschus.
4. described a kind of Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that according to claim 1-3, and injection preparation is specially:
Each component is pulverized respectively, be mixed in proportion, obtain mixture, add water to and flood mixture powder 3 ~ 5cm, soaked 1 ~ 2 hour, heating decocts, boil the rear slow fire of using, the rear decoction 2 ~ 4 hours of boiling for the first time leaches medicinal liquid, again add water in the filtering residue and flood mixture powder 3 ~ 5cm, heated and boiled is boiled the rear slow fire of using, the rear decoction 1 ~ 2 hour of boiling for the second time filters, and merges the medicinal liquid of twice filtration, adding accounts for quality of liquid medicine 0.5% active carbon, keeps pH value 7.0, heats little boiling 15 minutes, cooling, filter, get the 500ml filtrate, inject water to 1000ml, packed, in 115 ℃ of sterilizations 30 minutes, cold preservation 48 hours namely got injection.
5. described a kind of Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that according to claim 1-3, and soup potus preparation method is specially:
Each component is pulverized respectively, be mixed in proportion, obtain mixture, add water to and flood mixture powder 3 ~ 5cm, soaked 1 ~ 2 hour, heating decocts, boil the rear slow fire of using, the rear decoction 2 ~ 4 hours of boiling for the first time leaches medicinal liquid, again add water in the filtering residue and flood mixture powder 3 ~ 5cm, heated and boiled is boiled the rear slow fire of using, the rear decoction 1 ~ 2 hour of boiling for the second time, filter, the medicinal liquid that merges twice filtration centrifugal 30 minutes ~ 1 hour, extracts supernatant, being concentrated into crude drug concentration is 1g/ml ~ 2g/ml, obtains the soup potus.
6. described a kind of Chinese medicine composition for the treatment of ischemia apoplexy is characterized in that according to claim 1-3, and the capsule preparation method thereof process is:
By formula proportion with the conventional sorting of all medicines after → dry → be crushed to 300-400 order fine powder → mix homogeneously → incapsulate.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173688A (en) * | 2014-08-29 | 2014-12-03 | 曹丽丽 | Traditional Chinese medicine capsule for treating ischemic stroke and preparation method thereof |
| CN105012847A (en) * | 2015-08-10 | 2015-11-04 | 王艳娣 | Traditional Chinese medicine for preventing miscarriages and reinforcing uteri |
| CN105434987A (en) * | 2015-12-29 | 2016-03-30 | 杜小卫 | Traditional Chinese medicine preparation for treating cerebral infarction |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943726A (en) * | 2005-10-08 | 2007-04-11 | 周小明 | A Chinese traditional medicinal composition for treatment of ischemic apoplexy and its preparation method |
-
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943726A (en) * | 2005-10-08 | 2007-04-11 | 周小明 | A Chinese traditional medicinal composition for treatment of ischemic apoplexy and its preparation method |
Non-Patent Citations (3)
| Title |
|---|
| 张青萍等: "缺血性中风中药治疗研究进展", 《泛中医论坛.思考中医2006论文集》 * |
| 李鸿泓等: "中药治疗缺血性中风研究进展", 《山西中医》 * |
| 梁富英: "中风病中医研究进展", 《云南中医中药杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173688A (en) * | 2014-08-29 | 2014-12-03 | 曹丽丽 | Traditional Chinese medicine capsule for treating ischemic stroke and preparation method thereof |
| CN105012847A (en) * | 2015-08-10 | 2015-11-04 | 王艳娣 | Traditional Chinese medicine for preventing miscarriages and reinforcing uteri |
| CN105434987A (en) * | 2015-12-29 | 2016-03-30 | 杜小卫 | Traditional Chinese medicine preparation for treating cerebral infarction |
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Application publication date: 20130918 |