CN104146960A - 包含用抗粘添加剂进行表面修饰的颗粒的干粉吸入制剂 - Google Patents
包含用抗粘添加剂进行表面修饰的颗粒的干粉吸入制剂 Download PDFInfo
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- CN104146960A CN104146960A CN201410314552.XA CN201410314552A CN104146960A CN 104146960 A CN104146960 A CN 104146960A CN 201410314552 A CN201410314552 A CN 201410314552A CN 104146960 A CN104146960 A CN 104146960A
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- HDOZVRUNCMBHFH-UHFFFAOYSA-N zotepine Chemical compound CN(C)CCOC1=CC2=CC=CC=C2SC2=CC=C(Cl)C=C12 HDOZVRUNCMBHFH-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A—HUMAN NECESSITIES
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0425758.0 | 2004-11-23 | ||
| GBGB0425758.0A GB0425758D0 (en) | 2004-11-23 | 2004-11-23 | Preparation of pharmaceutical compositions |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CNA2005800470735A Division CN101106975A (zh) | 2004-11-23 | 2005-11-23 | 包含用抗粘添加剂进行表面修饰的颗粒的干粉吸入制剂 |
Publications (1)
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|---|---|
| CN104146960A true CN104146960A (zh) | 2014-11-19 |
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| CN201410314552.XA Pending CN104146960A (zh) | 2004-11-23 | 2005-11-23 | 包含用抗粘添加剂进行表面修饰的颗粒的干粉吸入制剂 |
| CNA2005800470735A Pending CN101106975A (zh) | 2004-11-23 | 2005-11-23 | 包含用抗粘添加剂进行表面修饰的颗粒的干粉吸入制剂 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| CNA2005800470735A Pending CN101106975A (zh) | 2004-11-23 | 2005-11-23 | 包含用抗粘添加剂进行表面修饰的颗粒的干粉吸入制剂 |
Country Status (16)
| Country | Link |
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| US (4) | US20080127972A1 (https=) |
| EP (4) | EP2311434B1 (https=) |
| JP (2) | JP5339401B2 (https=) |
| CN (2) | CN104146960A (https=) |
| AT (1) | ATE456363T1 (https=) |
| CA (1) | CA2589514C (https=) |
| DE (1) | DE602005019192D1 (https=) |
| DK (2) | DK2174653T3 (https=) |
| ES (3) | ES2490240T3 (https=) |
| GB (1) | GB0425758D0 (https=) |
| HU (1) | HUE027465T2 (https=) |
| IN (1) | IN2014CN04336A (https=) |
| PL (3) | PL1814521T3 (https=) |
| PT (3) | PT1814521E (https=) |
| SI (2) | SI2174653T1 (https=) |
| WO (1) | WO2006056812A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109200034A (zh) * | 2017-06-30 | 2019-01-15 | 正大天晴药业集团股份有限公司 | 一种可吸入干粉形式的组合物及其制备方法 |
| WO2025195446A1 (zh) * | 2024-03-20 | 2025-09-25 | 浙江萃泽医药科技有限公司 | 一种可吸入的药物粉末制剂及其制备方法 |
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- 2005-11-23 EP EP10179073.1A patent/EP2311434B1/en not_active Revoked
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- 2005-11-23 ES ES10151576.5T patent/ES2490240T3/es not_active Expired - Lifetime
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- 2005-11-23 DK DK10151576.5T patent/DK2174653T3/da active
- 2005-11-23 DK DK10179073.1T patent/DK2311434T3/en active
- 2005-11-23 EP EP15173932.3A patent/EP2949317B1/en not_active Revoked
- 2005-11-23 ES ES05808842T patent/ES2340599T3/es not_active Expired - Lifetime
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- 2005-11-23 AT AT05808842T patent/ATE456363T1/de active
- 2005-11-23 PL PL10179073T patent/PL2311434T3/pl unknown
- 2005-11-23 CN CN201410314552.XA patent/CN104146960A/zh active Pending
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- 2005-11-23 JP JP2007542131A patent/JP5339401B2/ja not_active Expired - Lifetime
- 2005-11-23 PT PT101515765T patent/PT2174653E/pt unknown
- 2005-11-23 ES ES10179073.1T patent/ES2548884T3/es not_active Expired - Lifetime
- 2005-11-23 US US11/791,385 patent/US20080127972A1/en not_active Abandoned
- 2005-11-23 DE DE602005019192T patent/DE602005019192D1/de not_active Expired - Lifetime
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- 2005-11-23 CN CNA2005800470735A patent/CN101106975A/zh active Pending
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109200034A (zh) * | 2017-06-30 | 2019-01-15 | 正大天晴药业集团股份有限公司 | 一种可吸入干粉形式的组合物及其制备方法 |
| WO2025195446A1 (zh) * | 2024-03-20 | 2025-09-25 | 浙江萃泽医药科技有限公司 | 一种可吸入的药物粉末制剂及其制备方法 |
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