CN104146955A - 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途 - Google Patents

含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途 Download PDF

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Publication number
CN104146955A
CN104146955A CN201410322762.3A CN201410322762A CN104146955A CN 104146955 A CN104146955 A CN 104146955A CN 201410322762 A CN201410322762 A CN 201410322762A CN 104146955 A CN104146955 A CN 104146955A
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CN
China
Prior art keywords
fatty acid
dha
oil mixture
epa
preconcentrate
Prior art date
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Pending
Application number
CN201410322762.3A
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English (en)
Chinese (zh)
Inventor
S.O.休斯特维特
P.H.奥尔森
G.伯格
J.E.J.克拉维尼斯
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Pronova Biopharma Norge AS
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Pronova Biocare AS
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Publication date
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Publication of CN104146955A publication Critical patent/CN104146955A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
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    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
CN201410322762.3A 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途 Pending CN104146955A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US15861309P 2009-03-09 2009-03-09
US61/158,613 2009-03-09
US24263009P 2009-09-15 2009-09-15
US61/242,630 2009-09-15
US25429309P 2009-10-23 2009-10-23
US25429109P 2009-10-23 2009-10-23
US61/254,293 2009-10-23
US61/254,291 2009-10-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2010800203059A Division CN102421422A (zh) 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途

Publications (1)

Publication Number Publication Date
CN104146955A true CN104146955A (zh) 2014-11-19

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ID=42727856

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201410322762.3A Pending CN104146955A (zh) 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途
CN2010800203059A Pending CN102421422A (zh) 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途
CN201910497672.0A Pending CN110538148A (zh) 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途

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CN2010800203059A Pending CN102421422A (zh) 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途
CN201910497672.0A Pending CN110538148A (zh) 2009-03-09 2010-03-09 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途

Country Status (17)

Country Link
US (6) US11612579B2 (enExample)
EP (4) EP3915554A1 (enExample)
JP (4) JP6176894B2 (enExample)
KR (3) KR101841756B1 (enExample)
CN (3) CN104146955A (enExample)
AU (1) AU2010222648B2 (enExample)
BR (1) BRPI1009431A2 (enExample)
CA (2) CA2754860C (enExample)
CO (1) CO6501136A2 (enExample)
EA (1) EA022028B1 (enExample)
ES (3) ES2979118T3 (enExample)
IL (1) IL215043A (enExample)
MX (1) MX2011009503A (enExample)
NZ (1) NZ595204A (enExample)
PH (1) PH12019500030A1 (enExample)
SG (1) SG174314A1 (enExample)
WO (3) WO2010103402A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105614638A (zh) * 2014-11-28 2016-06-01 深圳市前海安测信息技术有限公司 Dha纳米乳及其制备方法和其在健康保健饮品中的应用

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010222648B2 (en) * 2009-03-09 2016-07-07 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
SMT201800047T1 (it) 2009-04-29 2018-03-08 Amarin Pharmaceuticals Ie Ltd Composizione farmaceutica stabile e metodi di utilizzo della stessa
NZ720946A (en) 2009-04-29 2017-09-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
KR102012111B1 (ko) 2009-06-15 2019-08-19 아마린 파마, 인크. 병용 스타틴 요법을 받는 대상체에서 ldl-c 수준을 상승시키지 않으면서 트리글리세리드를 저하시키기 위한 조성물 및 방법
BR122019016628B8 (pt) 2009-09-23 2021-07-27 Amarin Corp Plc uso de uma composição compreendendo um derivado de hidróxi de atorvastatina ou sal farmaceuticamente aceitável do mesmo e um óleo compreendendo etil eicosapentaenoato ou etil docosahexaenoato para a fabricação de um medicamento para o tratamento de uma doença cardiovascular
US9717703B2 (en) * 2009-10-16 2017-08-01 Glaxosmithkline Llc Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed
CN102724972A (zh) * 2009-10-23 2012-10-10 普罗诺瓦生物医药挪威公司 脂肪酸油混合物的包衣胶囊和包衣片剂
JP5827625B2 (ja) 2009-10-29 2015-12-02 アカスティ ファーマ インコーポレイテッド 濃縮治療用リン脂質組成物
PE20130491A1 (es) 2009-12-30 2013-05-02 Basf Pharma Callanish Ltd Proceso simulado de separacion cromatografica de lecho movil para la purificacion de acidos grasos poliinsaturados
EP4056708A1 (en) 2010-01-19 2022-09-14 DSM IP Assets B.V. Isolated biomass from schizochytrium or thraustochytrium comprising epa and dha and its use in animal feed
US11236351B2 (en) 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
WO2012032415A2 (en) * 2010-09-08 2012-03-15 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture comprising epa and dha in free acid form, a surfactant, and a statin
WO2012032414A2 (en) * 2010-09-08 2012-03-15 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture, a surfactant, and a statin
US20140017308A1 (en) * 2010-09-08 2014-01-16 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture, a free fatty acid, and a statin
AU2011324909B2 (en) * 2010-11-05 2016-09-08 Pronova Biopharma Norge As Methods of treatment using lipid compounds
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
WO2012074930A2 (en) 2010-11-29 2012-06-07 Amarin Pharma, Inc. Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
CA2827555A1 (en) * 2011-02-16 2012-08-23 Pivotal Therapeutics, Inc. Cholesterol absorption inhibitor (azetidinone) and omega 3 fatty acids (epa, dha, dpa) for the reduction of cholesterol and for the reduction of cardiovascular events
CA2827579A1 (en) * 2011-02-16 2012-08-23 Pivotal Therapeutics, Inc. Omega 3 formulations comprising epa, dha and dpa for treatment of risk factors for cardiovascular disease
US20120302639A1 (en) * 2011-02-16 2012-11-29 Pivotal Therapeutics Inc. Omega 3 formulations for treatment of risk factors for cardiovascular disease and protection against sudden death
US8715648B2 (en) 2011-02-16 2014-05-06 Pivotal Therapeutics Inc. Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics
JP2014505732A (ja) * 2011-02-16 2014-03-06 ピヴォタル セラピューティクス インコーポレイテッド 心血管疾患において用いるための、スタチンおよびω3脂肪酸(EPA、DHAおよびDPA)
US8951514B2 (en) * 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
US8952000B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
JP2014506891A (ja) * 2011-02-16 2014-03-20 ピヴォタル セラピューティクス インコーポレイテッド 心血管疾患(CVD)患者の食事管理のためのω3脂肪酸診断アッセイ
US9119826B2 (en) * 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US8697676B2 (en) * 2011-06-15 2014-04-15 Ronald E Rosedale Omega-3 fatty acid nutriceutical composition and optimization method
US10383839B2 (en) 2011-06-30 2019-08-20 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
ES2857173T3 (es) * 2011-07-21 2021-09-28 Dsm Ip Assets Bv Aceites microbianos enriquecidos en ácidos grasos poliinsaturados
AU2012285806B2 (en) 2011-07-21 2017-09-14 Dsm Ip Assets B.V. Fatty acid compositions
TW201307553A (zh) * 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
WO2013072767A1 (en) * 2011-11-18 2013-05-23 Pronova Biopharma Norge As Compositions and preconcentrates comprising at least one salicylate and omega-3 fatty acid oil mixture
JP6399655B2 (ja) 2012-01-06 2018-10-03 オムセラ・ファーマシューティカルズ・インコーポレイテッド 遊離酸型のオメガ−3多価不飽和脂肪酸のdpa濃縮組成物
AU2013235266B2 (en) 2012-03-20 2017-10-19 Particle Dynamics International, Llc Gelling agent-based dosage form
US20160228397A1 (en) * 2012-03-30 2016-08-11 Sancilio & Company, Inc. Omega-3 fatty acid ester compositions
US20150132389A1 (en) * 2012-03-30 2015-05-14 Sancilio & Company, Inc. Omega-3 Fatty Acid Ester Compositions
US20150125529A1 (en) * 2012-03-30 2015-05-07 Sancilio & Company, Inc. Omega-3 Fatty Acid Ester Compositions
HK1204978A1 (zh) * 2012-03-30 2015-12-11 桑茨利奥&孔帕尼股份有限公司 ω-3脂肪酸酯组合物
US9480651B2 (en) * 2012-03-30 2016-11-01 Sancilio & Company, Inc. Omega-3 fatty acid ester compositions unitary pharmaceutical dosage forms
US10898458B2 (en) 2012-03-30 2021-01-26 Micelle Biopharma, Inc. Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states
EP2846779A4 (en) 2012-05-07 2015-12-16 Omthera Pharmaceuticals Inc STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS
KR20250164338A (ko) * 2012-05-14 2025-11-24 가부시키가이샤 닛스이 환경 오염 물질을 저감시킨 고도 불포화 지방산 또는 고도 불포화 지방산 에틸에스테르 및 그 제조 방법
US20140194512A1 (en) * 2012-06-17 2014-07-10 Matinas Biopharma, Inc. Compositions comprising docosapentaenoic acid and methods of use
AU2013277441B2 (en) 2012-06-17 2017-07-06 Matinas Biopharma, Inc. Omega-3 pentaenoic acid compositions and methods of use
WO2014074552A2 (en) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
CN103015230B (zh) * 2012-11-27 2015-04-01 广州嘉德乐生化科技有限公司 一种单硬脂酸甘油酯和聚氧乙烯醚脂肪酸皂的组合物
KR20210059779A (ko) * 2012-12-06 2021-05-25 마티나스 바이오파마, 인코포레이티드 오메가-3 펜타엔산 조성물 및 사용 방법
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
EP3578170A1 (en) * 2013-02-28 2019-12-11 Basf As A composition comprising a lipid compound, a triglyceride, and a surfactant, and methods of using the same
JP2016518315A (ja) * 2013-03-13 2016-06-23 マティナス バイオファーマ インコーポレイテッド ω3ペンタエン酸組成物および使用方法
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US20140322314A1 (en) * 2013-04-29 2014-10-30 Matinas Biopharma, Inc. Omega-3 Fatty Acid Formulations for Use as Pharmaceutical Treatment
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP3023099B1 (en) 2013-07-18 2020-09-30 Mochida Pharmaceutical Co., Ltd. Self-emulsifying composition of -3 fatty acid
JPWO2015008849A1 (ja) 2013-07-18 2017-03-02 持田製薬株式会社 ω3脂肪酸の自己乳化組成物
WO2015011724A2 (en) * 2013-07-22 2015-01-29 Kms Health Center Pvt Ltd A novel omega -3 fatty acid composition with a plant extract
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
EP2883860B1 (fr) 2013-12-11 2016-08-24 Novasep Process Procédé chromatographique de production d'acides gras polyinsaturés
US9745538B2 (en) 2013-12-20 2017-08-29 MARA Renewables Corporation Methods of recovering oil from microorganisms
EP3092218B1 (fr) 2014-01-07 2022-03-09 Novasep Process Solutions Procédé de purification d'acides aminés aromatiques
US10143674B2 (en) * 2014-01-28 2018-12-04 Fresenius Kabi Deutschland Gmbh Composition comprising EPA and DHA triglycerides for parenteral administration
IN2014CH01872A (enExample) 2014-04-09 2015-05-08 Nanoceutica Lab Pvt Ltd
EP3906920A1 (en) * 2014-06-06 2021-11-10 Marine Ingredients, LLC Omega-3 compositions, dosage forms, and methods of use
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US20160120964A1 (en) * 2014-11-05 2016-05-05 George Shlieout Processes for producing compositions with improved safety profile having lipase activity and compositions suitable for pharmaceutical use
US11007161B1 (en) * 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
US10561627B2 (en) * 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
MX384954B (es) 2015-01-21 2025-03-14 Mochida Pharm Co Ltd Composición auto-emulsionante de ácido graso ?3.
JP6806339B2 (ja) * 2015-06-02 2021-01-06 日東薬品工業株式会社 新規なトリグリセリド及びその用途
RU2655803C2 (ru) * 2016-03-10 2018-05-29 АД Смарт, СИА Фармацевтическая композиция для профилактики и лечения атеросклероза
EP3429377B1 (en) * 2016-03-16 2020-09-09 Golden Omega Norway AS Powders and tablets comprising omega-3 fatty acid derivatives and method for their production
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
CN106072611A (zh) * 2016-06-20 2016-11-09 威海百合生物技术股份有限公司 一种含不饱和脂肪酸的多相稀释组合物
GB201611920D0 (en) * 2016-07-08 2016-08-24 Astrazeneca Ab Pharmaceutical compositions
AU2017301077B2 (en) * 2016-08-12 2022-07-07 Pharmako Biotechnologies Pty Limited Omega-3 compositions and methods relating thereto
WO2018054265A1 (zh) * 2016-09-20 2018-03-29 张碧婷 亲水性脂类组合物的包装组合物,其制备及调配方法和应用
WO2018116093A1 (en) 2016-12-22 2018-06-28 MARA Renewables Corporation Methods for producing biomass rich in dha, palmitic acid and protein using a eukaryotic microorganism
CN107048405A (zh) * 2017-03-03 2017-08-18 武汉锶博睿医药技术有限公司 脂肪酸组件微胶囊及其制备方法
GR1009542B (el) 2018-04-25 2019-06-07 Φαρματεν Α.Β.Ε.Ε. Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
ES2983568T3 (es) 2018-09-24 2024-10-23 Amarin Pharmaceuticals Ie Ltd Métodos para reducir el riesgo de eventos cardiovasculares en un sujeto
KR20210097153A (ko) 2018-11-30 2021-08-06 에보니크 오퍼레이션즈 게엠베하 인지질 및 지방산 염의 분산액을 포함하는 제제
CA3137085A1 (en) 2019-04-18 2020-10-22 Akershus Universitetssykehus Hf Combination therapy comprising an ffar4 agonist and an alpha-7 nachr agonist or positive modulator
KR102096391B1 (ko) * 2019-10-11 2020-04-06 (주)아이엠디팜 액상결정 구조체를 형성하는 오메가-3-지방산 조성물
CN110584084A (zh) * 2019-10-17 2019-12-20 广州白云山汉方现代药业有限公司 一种乳化稳定剂及含该乳化稳定剂的营养乳液
EP4058141A4 (en) 2019-11-12 2023-11-22 Amarin Pharmaceuticals Ireland Limited METHOD FOR REDUCING THE RISK OF CARDIOVASCULAR EVENTS IN A SUBJECT WITH Atrial fibrillation and/or atrial flutter
WO2021199009A1 (en) 2020-04-03 2021-10-07 MARA Renewables Corporation Microbial oils with high levels of omega-3 fatty acids
CN113827547A (zh) * 2020-06-23 2021-12-24 南京清普生物科技有限公司 一种缓释制剂组合物
CN111729125B (zh) * 2020-07-31 2022-10-04 陕西佰傲再生医学有限公司 骨止血材料
JP2021008518A (ja) * 2020-10-21 2021-01-28 持田製薬株式会社 ω3脂肪酸の自己乳化組成物
AU2022263358A1 (en) 2021-04-21 2023-11-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure
CN116407543B (zh) * 2021-12-29 2025-12-12 中国科学院上海药物研究所 Epa-ee纳米脂质组合物、及其制剂、制备方法和应用
KR20230161551A (ko) * 2022-05-18 2023-11-28 부광약품 주식회사 제제학적으로 안정성이 향상된 연질 캡슐

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284268B1 (en) * 1997-12-10 2001-09-04 Cyclosporine Therapeutics Limited Pharmaceutical compositions containing an omega-3 fatty acid oil
CN1968689A (zh) * 2004-06-18 2007-05-23 狄洛特医药有限公司 包含多不饱和脂肪酸和至少一种免疫抑制剂或抗肿瘤剂的药物组合物

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5312473B1 (enExample) 1971-05-24 1978-05-01
GB2033745B (en) 1978-05-26 1983-08-17 Wellcome Found Fatty acid and derivatives thereof for use in treatment or prophylaxis of thromboembolic conditions
PH19942A (en) 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
AU552068B2 (en) * 1981-09-21 1986-05-22 Asama Chemical Co. Ltd. Preservation of edible oils
WO1984002271A1 (en) 1982-12-09 1984-06-21 Hafsten Raymond J Jr Readily-absorpable fatty acid emulsions
JPS60100516A (ja) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4843095A (en) * 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
GB2209937B (en) 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
US5035896A (en) 1988-06-15 1991-07-30 Warner-Lambert Company Water insoluble drugs coated by coacervated fish gelatin
GB8819110D0 (en) 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
EP0487575B1 (en) 1989-08-17 1994-11-02 Cortecs Limited Pharmaceutical formulations
US5532002A (en) * 1989-08-17 1996-07-02 Cortecs Limited Gelatin pharmaceutical formulations
CH683149A5 (fr) 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5501077A (en) * 1994-05-27 1996-03-26 Springwell Dispensers, Inc. Thermoelectric water chiller
JPH0889167A (ja) 1994-09-27 1996-04-09 Nippon Oil & Fats Co Ltd 多価不飽和脂肪酸含有醗酵乳の製造方法
MY118354A (en) 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
GB9509764D0 (en) 1995-05-15 1995-07-05 Tillotts Pharma Ag Treatment of inflammatory bowel disease using oral dosage forms of omega-3 polyunsaturated acids
DE19608137A1 (de) * 1996-03-02 1997-09-04 Meyer Lucas Gmbh & Co Lipid-Zubereitungen für diätetische Zwecke
KR100300251B1 (ko) 1997-12-05 2001-10-29 김용규 사이클로스포린함유약학적조성물
AU1809499A (en) 1997-12-10 1999-06-28 Awadhesh K. Mishra Self-emulsifying fenofibrate formulations
AU3843999A (en) * 1998-05-07 1999-11-23 Elan Corporation, Plc Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
GB9901809D0 (en) * 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
US20050037065A1 (en) 1999-05-27 2005-02-17 Drugtech Corporation Nutritional formulations
ATE305810T1 (de) 2000-05-22 2005-10-15 Pro Aparts Investimentos E Con Fettsäure enthaltende pharmazeutische zusammensetzung die wenigstens 80 gew. epa und dha enthält
EP1279400A1 (en) * 2001-07-25 2003-01-29 Target Hit sa Modifying the fatty acid composition of cell membranes of organs and tissues
KR100441167B1 (ko) 2001-12-27 2004-07-21 씨제이 주식회사 마이크로에멀젼 예비 농축액 조성물
ITMI20020269A1 (it) 2002-02-12 2003-08-12 Victorix Assets Ltd Uso di steri etilici di acidi poliinsaturi omega-3 in pazienti con insufficienza cardiaca
GB0210212D0 (en) * 2002-05-03 2002-06-12 Univ Southampton Effects of dietary N-3 and N-6 pufa intake on atheromatous plaque stability
ITMI20022511A1 (it) 2002-11-26 2004-05-27 Victorix Assets Ltd Uso di composizioni farmaceutiche contenenti esteri etilici di acidi poliinsaturi omega-3 nella orevenzione della fibrillazione atriale.
US20040254357A1 (en) 2002-12-19 2004-12-16 Zaloga Gary P. Fatty acid phenolic conjugates
WO2004056370A1 (en) 2002-12-20 2004-07-08 Pronova Biocare As Use of a fatty acid composition for treatment of male infertility
SE0303513D0 (sv) * 2003-12-19 2003-12-19 Pronova Biocare As Use of a fatty acid composition comprising at least one of epa and dha or any combinations thereof
GB0403247D0 (en) * 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
GB0413729D0 (en) 2004-06-18 2004-07-21 Tillotts Pharma Ag A pharmaceutical composition and its use
US20090030077A1 (en) * 2004-08-06 2009-01-29 Transform Pharmaceuticals Inc. Novel Fenofibrate Formulations and Related Methods of Treatment
MX2007001553A (es) * 2004-08-06 2008-03-07 Transform Pharmaceuticals Inc Nuevas composiciones farmaceuticas de estatina y metodos de tratamiento relacionados.
AU2005271407A1 (en) * 2004-08-06 2006-02-16 Transform Pharmaceuticals, Inc. Novel fenofibrate formulations and related methods of treatment
WO2006018024A2 (en) * 2004-08-18 2006-02-23 Ace Aps Cosmetic and pharmaceutical compositions comprising ace inhibitors and/or angiotensin ii receptor antagonists
US20060051462A1 (en) * 2004-09-03 2006-03-09 Wang Jimmy X Self emulsifying compositions for delivering lipophilic coenzyme Q10 and other dietary ingredients
CN101098690A (zh) * 2004-12-06 2008-01-02 瑞莱恩特医药品有限公司 用于血脂治疗的ω-3脂肪酸和脂血异常剂
GB0428384D0 (en) * 2004-12-24 2005-02-02 Sla Pharma Ag Eicosapentaenoic acid
JP5503846B2 (ja) * 2005-01-24 2014-05-28 プロノヴァ・バイオファーマ・ノルゲ・アーエス アミロイドーシス関連疾患の治療のための医療品又は食料品の製造における、dhaを含有する脂肪酸組成物の使用
CA2600429A1 (en) 2005-03-08 2006-09-14 Reliant Pharmaceuticals, Inc. Treatment with statin and omega-3 fatty acids and a combination product thereof
TWI412361B (zh) 2005-07-08 2013-10-21 Mochida Pharm Co Ltd 預防心血管症候用組成物
ITMI20051560A1 (it) * 2005-08-10 2007-02-11 Tiberio Bruzzese Composizione di acidi grassi n-3 con elevata concentrazione di epa e-o dha e contenente acidi grassi n-6
US7652068B2 (en) * 2005-12-20 2010-01-26 Cenestra Llc Omega 3 fatty acid formulations
CN101484148A (zh) 2006-02-10 2009-07-15 斯博茨科姆丹麦私人有限公司 包衣片剂及其制备方法和相关用途
MY153288A (en) 2006-06-28 2015-01-29 Hovid Berhad An effective pharmaceutical carrier for poorly bioavailable drugs
JP2009544701A (ja) * 2006-07-21 2009-12-17 リライアント・ファーマシューティカルズ・インコーポレイテッド オメガ3脂肪酸を含む組成物、ならびに末梢動脈障害および間欠性跛行を処置するためのそれらの使用
WO2008011179A2 (en) 2006-07-21 2008-01-24 Reliant Pharmaceuticals, Inc. Omega-3 fatty acids for use in treating resistant hypertension
US7676518B2 (en) 2006-08-16 2010-03-09 Sap Ag Clustering for structured data
JP2010506920A (ja) 2006-10-18 2010-03-04 リライアント・ファーマシューティカルズ・インコーポレイテッド Lp−pla2濃度を減少させるためのオメガ−3脂肪酸
CA2677670C (en) * 2007-03-20 2010-08-03 Centre De Recherche Sur Les Biotechnologies Marines Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof
PL2124973T3 (pl) * 2007-03-23 2015-10-30 Novartis Ag Kompozycja zawierająca kwasy tłuszczowe omega-3 oraz zamaskowane lub powleczone sole miedzi
US20080261896A1 (en) 2007-04-11 2008-10-23 Sinphar Pharmaceutical Co., Ltd. Testosterone generating and metabolizing enhancer
US20090011012A1 (en) 2007-07-06 2009-01-08 Baum Seth J Fatty acid compositions and methods of use
WO2009087939A1 (ja) 2008-01-04 2009-07-16 University Of Yamanashi 秘匿通信方法
EA201200829A1 (ru) 2008-01-10 2012-11-30 Такеда Фармасьютикал Компани Лимитед Состав капсулы
US20100062057A1 (en) 2008-09-10 2010-03-11 Pronova BioPharma Norge AS. Formulation
US20100130608A1 (en) 2008-10-01 2010-05-27 Martek Biosciences Corporation Compositions and methods for reducing triglyceride levels
AU2010222648B2 (en) * 2009-03-09 2016-07-07 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof
US9717703B2 (en) 2009-10-16 2017-08-01 Glaxosmithkline Llc Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed
CN102724972A (zh) 2009-10-23 2012-10-10 普罗诺瓦生物医药挪威公司 脂肪酸油混合物的包衣胶囊和包衣片剂

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284268B1 (en) * 1997-12-10 2001-09-04 Cyclosporine Therapeutics Limited Pharmaceutical compositions containing an omega-3 fatty acid oil
CN1968689A (zh) * 2004-06-18 2007-05-23 狄洛特医药有限公司 包含多不饱和脂肪酸和至少一种免疫抑制剂或抗肿瘤剂的药物组合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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