CN104080905B - 细胞培养基和方法 - Google Patents
细胞培养基和方法 Download PDFInfo
- Publication number
- CN104080905B CN104080905B CN201280068225.XA CN201280068225A CN104080905B CN 104080905 B CN104080905 B CN 104080905B CN 201280068225 A CN201280068225 A CN 201280068225A CN 104080905 B CN104080905 B CN 104080905B
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- medium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
- B01J13/22—Coating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
- B29C67/24—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 characterised by the choice of material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2009/00—Layered products
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/32—Polylysine, polyornithine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/72—Chitin, chitosan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/76—Agarose, agar-agar
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/78—Cellulose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/80—Hyaluronan
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- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611042079.XA CN106635949B (zh) | 2011-12-22 | 2012-12-21 | 细胞培养基和方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579432P | 2011-12-22 | 2011-12-22 | |
| US61/579,432 | 2011-12-22 | ||
| PCT/US2012/071411 WO2013096858A1 (en) | 2011-12-22 | 2012-12-21 | Cell culture media and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611042079.XA Division CN106635949B (zh) | 2011-12-22 | 2012-12-21 | 细胞培养基和方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104080905A CN104080905A (zh) | 2014-10-01 |
| CN104080905B true CN104080905B (zh) | 2016-11-16 |
Family
ID=47557531
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611042079.XA Active CN106635949B (zh) | 2011-12-22 | 2012-12-21 | 细胞培养基和方法 |
| CN201280068225.XA Active CN104080905B (zh) | 2011-12-22 | 2012-12-21 | 细胞培养基和方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611042079.XA Active CN106635949B (zh) | 2011-12-22 | 2012-12-21 | 细胞培养基和方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9410118B2 (enExample) |
| EP (2) | EP3702442B1 (enExample) |
| JP (4) | JP6216327B2 (enExample) |
| KR (1) | KR102039494B1 (enExample) |
| CN (2) | CN106635949B (enExample) |
| WO (1) | WO2013096858A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190092629A (ko) | 2011-02-07 | 2019-08-07 | 라이프 테크놀로지스 코포레이션 | 감수성 화합물을 안정화시키는 조성물 및 방법 |
| KR102039494B1 (ko) * | 2011-12-22 | 2019-11-01 | 라이프 테크놀로지스 코포레이션 | 세포 배양 배지 및 방법 |
| EP3019594B1 (en) * | 2013-07-11 | 2020-12-02 | Merck Patent GmbH | Cell culture media |
| CN105934511B (zh) * | 2014-01-23 | 2021-01-22 | 日产化学工业株式会社 | 培养基组合物 |
| US20150275167A1 (en) * | 2014-03-28 | 2015-10-01 | Corning Incorporated | Composition and method for cell culture sustained release |
| KR20160144429A (ko) * | 2014-04-10 | 2016-12-16 | 바이엘 헬쓰케어 엘엘씨 | 배합된 배지 분말 제형 및 세포 배양을 위한 액체 배지의 제조 방법 |
| PL3303562T3 (pl) * | 2015-06-08 | 2023-05-08 | Corning Incorporated | Formulacja susząca dla mikronośników hydrożelowych |
| WO2017085321A1 (en) * | 2015-11-20 | 2017-05-26 | Qiagen Gmbh | Method of preparing sterilized compositions for stabilization of extracellular nucleic acids |
| US10822584B2 (en) * | 2015-12-17 | 2020-11-03 | Life Technologies Corporation | Pellets used in cell culture and methods of making thereof |
| CN108699510A (zh) * | 2015-12-30 | 2018-10-23 | 生命技术公司 | 细胞培养用层状颗粒及其制法 |
| CN106222236A (zh) * | 2016-07-27 | 2016-12-14 | 郑州点石生物技术有限公司 | 血液中微生物检测试剂及其制备方法 |
| CN109395095B (zh) * | 2017-09-18 | 2021-09-24 | 武汉原生原代生物医药科技有限公司 | 体内用生物膜及其制备方法和用途 |
| JPWO2020022511A1 (ja) * | 2018-07-27 | 2021-08-02 | 味の素株式会社 | 動物細胞の浮遊培養用の添加物、浮遊培養用培地および浮遊培養方法 |
| CN111849879A (zh) * | 2020-08-07 | 2020-10-30 | 张娇 | 一种细胞培养基及细胞培养方法 |
| CN112553116A (zh) * | 2020-12-23 | 2021-03-26 | 邢箫 | 一种益生菌培养基及益生菌制剂 |
| WO2024096506A1 (ko) * | 2022-10-31 | 2024-05-10 | 삼성바이오에피스 주식회사 | 고농도 액체 배지 제조 방법 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003005989A2 (en) * | 2001-07-11 | 2003-01-23 | Apr Applied Pharma Research Sa | Granulates containing liposoluble substances and a process for the preparation thereof |
| WO2011049547A1 (en) * | 2009-10-21 | 2011-04-28 | Dow Pharmaceutical Sciences, Inc. | Method for wetting a powder containing benzoyl peroxide |
| WO2011136274A1 (ja) * | 2010-04-28 | 2011-11-03 | 株式会社フジクラ | 光ファイバケーブル |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3870061D1 (de) * | 1987-06-19 | 1992-05-21 | Univ Temple | Mikrokapseln mit gelenkter freigabe und verfahren zu deren herstellung. |
| JPS6413986A (en) * | 1987-07-08 | 1989-01-18 | Mitsuiwa Eng Kk | Microcapsule for cultivating cell and production thereof |
| EP0626170A3 (en) * | 1993-05-10 | 1996-03-27 | Sandoz Ltd | Stabilization of pharmacologically active compounds in delayed release agents. |
| US6281015B1 (en) * | 1994-12-16 | 2001-08-28 | Children's Medical Center Corp. | Localized delivery of factors enhancing survival of transplanted cells |
| EP2221361A3 (en) * | 1996-08-30 | 2011-02-09 | Life Technologies Corporation | Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium |
| US6383810B2 (en) | 1997-02-14 | 2002-05-07 | Invitrogen Corporation | Dry powder cells and cell culture reagents and methods of production thereof |
| ES2169980B1 (es) * | 1999-12-17 | 2003-11-01 | Lipotec Sa | Microcapsulas para la liberacion prolongada de farmacos. |
| JP2002114667A (ja) * | 2000-10-11 | 2002-04-16 | Ltt Institute Co Ltd | 徐放性製剤用組成物、その製造法および徐放性マイクロカプセル製剤 |
| JP2004521615A (ja) * | 2000-11-06 | 2004-07-22 | インヴィトロジェン コーポレーション | 乾燥粉末細胞および細胞培養試薬およびその生産の方法 |
| ATE462781T1 (de) * | 2001-11-30 | 2010-04-15 | Life Technologies Corp | Zellkulturmedien |
| US6974592B2 (en) * | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| AU2003303525A1 (en) * | 2002-12-31 | 2004-07-29 | Ultra-Sonic Technologies, L.L.C. | Transdermal delivery using encapsulated agent activated by ultrasound and/or heat |
| ES2389441T3 (es) | 2004-01-08 | 2012-10-26 | North Carolina State University | Métodos y dispositivos para el microencapsulamiento de células |
| US7740861B2 (en) | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
| WO2007094000A2 (en) * | 2006-02-15 | 2007-08-23 | Botanocap Ltd. | Applications of microencapsulated essential oils |
| US20110262965A1 (en) | 2010-04-23 | 2011-10-27 | Life Technologies Corporation | Cell culture medium comprising small peptides |
| JP5820874B2 (ja) | 2010-04-30 | 2015-11-24 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | N−(4−(2−アミノ−3−クロロピリジン−4−イルオキシ)−3−フルオロフェニル)−4−エトキシ−1−(4−フルオロフェニル)−2−オキソ−1,2−ジヒドロピリジン−3−カルボキサミドを含有する医薬組成物 |
| KR20190092629A (ko) * | 2011-02-07 | 2019-08-07 | 라이프 테크놀로지스 코포레이션 | 감수성 화합물을 안정화시키는 조성물 및 방법 |
| KR102039494B1 (ko) * | 2011-12-22 | 2019-11-01 | 라이프 테크놀로지스 코포레이션 | 세포 배양 배지 및 방법 |
-
2012
- 2012-12-21 KR KR1020147019999A patent/KR102039494B1/ko active Active
- 2012-12-21 US US14/367,413 patent/US9410118B2/en active Active
- 2012-12-21 JP JP2014548973A patent/JP6216327B2/ja active Active
- 2012-12-21 EP EP20170574.6A patent/EP3702442B1/en active Active
- 2012-12-21 CN CN201611042079.XA patent/CN106635949B/zh active Active
- 2012-12-21 CN CN201280068225.XA patent/CN104080905B/zh active Active
- 2012-12-21 EP EP12814100.9A patent/EP2794853B1/en active Active
- 2012-12-21 WO PCT/US2012/071411 patent/WO2013096858A1/en not_active Ceased
-
2016
- 2016-06-30 US US15/198,237 patent/US10066200B2/en active Active
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2017
- 2017-09-22 JP JP2017181983A patent/JP6457041B2/ja active Active
-
2018
- 2018-08-03 US US16/054,601 patent/US20180346872A1/en not_active Abandoned
- 2018-12-19 JP JP2018236870A patent/JP6843824B2/ja active Active
-
2020
- 2020-07-01 US US16/918,838 patent/US12203095B2/en active Active
-
2021
- 2021-02-24 JP JP2021026972A patent/JP7217765B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003005989A2 (en) * | 2001-07-11 | 2003-01-23 | Apr Applied Pharma Research Sa | Granulates containing liposoluble substances and a process for the preparation thereof |
| WO2011049547A1 (en) * | 2009-10-21 | 2011-04-28 | Dow Pharmaceutical Sciences, Inc. | Method for wetting a powder containing benzoyl peroxide |
| WO2011136274A1 (ja) * | 2010-04-28 | 2011-11-03 | 株式会社フジクラ | 光ファイバケーブル |
Non-Patent Citations (1)
| Title |
|---|
| Novel aspects of wet milling for the production of microsuspensions and nanosuspensions of porrly water-soluble drugs;ANAGHA BHAKAY ET AL;《DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY》;20110801;第37卷(第8期);全文 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6216327B2 (ja) | 2017-10-18 |
| US9410118B2 (en) | 2016-08-09 |
| US20180346872A1 (en) | 2018-12-06 |
| KR102039494B1 (ko) | 2019-11-01 |
| JP6457041B2 (ja) | 2019-01-23 |
| JP7217765B2 (ja) | 2023-02-03 |
| US20150064785A1 (en) | 2015-03-05 |
| CN106635949A (zh) | 2017-05-10 |
| JP2021087446A (ja) | 2021-06-10 |
| US20200332250A1 (en) | 2020-10-22 |
| EP2794853B1 (en) | 2020-04-22 |
| EP3702442B1 (en) | 2025-06-25 |
| US20160376548A1 (en) | 2016-12-29 |
| JP6843824B2 (ja) | 2021-03-17 |
| EP2794853A1 (en) | 2014-10-29 |
| CN106635949B (zh) | 2020-05-19 |
| KR20140113693A (ko) | 2014-09-24 |
| CN104080905A (zh) | 2014-10-01 |
| EP3702442A1 (en) | 2020-09-02 |
| US12203095B2 (en) | 2025-01-21 |
| JP2015503329A (ja) | 2015-02-02 |
| JP2018038404A (ja) | 2018-03-15 |
| US10066200B2 (en) | 2018-09-04 |
| WO2013096858A1 (en) | 2013-06-27 |
| JP2019062901A (ja) | 2019-04-25 |
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