PL3303562T3 - Formulacja susząca dla mikronośników hydrożelowych - Google Patents

Formulacja susząca dla mikronośników hydrożelowych

Info

Publication number
PL3303562T3
PL3303562T3 PL16732406.0T PL16732406T PL3303562T3 PL 3303562 T3 PL3303562 T3 PL 3303562T3 PL 16732406 T PL16732406 T PL 16732406T PL 3303562 T3 PL3303562 T3 PL 3303562T3
Authority
PL
Poland
Prior art keywords
drying formulation
microcarriers
hydrogel
hydrogel microcarriers
formulation
Prior art date
Application number
PL16732406.0T
Other languages
English (en)
Inventor
Paula Jean DOLLEY-SONNEVILLE
David Henry
Jeffery Joseph SCIBEK
Yue Zhou
Original Assignee
Corning Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corning Incorporated filed Critical Corning Incorporated
Publication of PL3303562T3 publication Critical patent/PL3303562T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C12N5/0075—General culture methods using substrates using microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
    • C12N2500/62—DMSO
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/99—Serum-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
    • C12N2537/10—Cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PL16732406.0T 2015-06-08 2016-06-08 Formulacja susząca dla mikronośników hydrożelowych PL3303562T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562172449P 2015-06-08 2015-06-08
PCT/US2016/036464 WO2016200954A1 (en) 2015-06-08 2016-06-08 Drying formulation for hydrogel microcarriers

Publications (1)

Publication Number Publication Date
PL3303562T3 true PL3303562T3 (pl) 2023-05-08

Family

ID=56236091

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16732406.0T PL3303562T3 (pl) 2015-06-08 2016-06-08 Formulacja susząca dla mikronośników hydrożelowych

Country Status (6)

Country Link
US (2) US10900021B2 (pl)
EP (1) EP3303562B1 (pl)
JP (1) JP6930925B2 (pl)
CN (1) CN107750274A (pl)
PL (1) PL3303562T3 (pl)
WO (1) WO2016200954A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3911730A1 (en) * 2019-01-16 2021-11-24 Corning Incorporated Systems and methods for culturing cells in suspension
CN111559542B (zh) * 2020-05-15 2022-03-04 北京华龛生物科技有限公司 一种使微载体聚集体保留吸水分散特性的辐照灭菌方法
JP7281116B2 (ja) 2021-05-11 2023-05-25 大日本印刷株式会社 乾燥マイクロキャリアおよびその製造方法
CN114958709B (zh) * 2021-12-07 2024-04-19 中科睿极(海宁)生物科技有限公司 可快速崩解的微载体聚集体及其制备方法
CN115518197B (zh) * 2022-07-25 2024-03-19 上海大学 用于骨缺损修复的聚氨基酸纳米纤维开口中空微载体、其制备方法及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0611290B2 (ja) 1986-11-05 1994-02-16 住友ベークライト株式会社 ポリビニルアルコ−ルゲルのγ線滅菌法
US6313103B1 (en) * 1998-05-13 2001-11-06 Carrington Laboratories, Inc. Pectic substance as a growth factor stabilizer
WO2005014774A1 (ja) 2003-08-11 2005-02-17 National Institute Of Agrobiological Sciences 動物細胞の培養担体と、該培養担体を用いた動物細胞の培養方法および移植方法
JP5179381B2 (ja) 2006-02-17 2013-04-10 ノバルティス アーゲー ヒドロゲルコンタクトレンズの滅菌方法
US20070218038A1 (en) 2006-03-17 2007-09-20 Pegasus Biologics, Inc. Stabilized, sterilized collagen scaffolds with active adjuncts attached
EP1938690B1 (de) 2006-12-22 2013-10-23 Preentec AG Sterilisierung und Konservierung von Fluiden
WO2009132224A2 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Rehydratable thiolated polysaccharide particles and sponge
EP2288389B1 (en) 2008-04-24 2014-06-11 Medtronic, Inc Cold ionizing radiation sterilization
US9068182B2 (en) * 2009-07-28 2015-06-30 Corning Incorporated Synthetic polysaccharide microcarriers for culturing cells
CN102686245B (zh) 2009-10-29 2015-09-30 阿森迪斯药物股份有限公司 可生物降解水凝胶的消毒
US8721963B2 (en) 2010-03-29 2014-05-13 University Of South Carolina Cold sterilization of tissue engineering scaffolds with compressed carbon dioxide
US20160145567A1 (en) 2010-05-27 2016-05-26 Corning Incorporated Cell culture article and methods thereof
US10441610B2 (en) * 2010-11-23 2019-10-15 Georgia Tech Research Corporation Protein delivery from stem cell microcarriers
CN102250390B (zh) 2011-05-25 2012-10-31 天津大学 海藻酸盐水凝胶微载体及其制备方法
WO2013070775A1 (en) 2011-11-07 2013-05-16 C.R. Bard, Inc Ruggedized ultrasound hydrogel insert
AU2014302772A1 (en) 2013-06-24 2016-01-28 Celularity Inc. Extracellular matrix composition beads for cell culture
CN105492595B (zh) * 2013-06-24 2021-02-12 康宁股份有限公司 细胞培养制品及其方法
WO2016200888A1 (en) 2015-06-08 2016-12-15 Corning Incorporated Digestible substrates for cell culture

Also Published As

Publication number Publication date
EP3303562B1 (en) 2023-01-11
CN107750274A (zh) 2018-03-02
US10900021B2 (en) 2021-01-26
JP2018516578A (ja) 2018-06-28
JP6930925B2 (ja) 2021-09-01
US20180171301A1 (en) 2018-06-21
US20210207098A1 (en) 2021-07-08
WO2016200954A1 (en) 2016-12-15
EP3303562A1 (en) 2018-04-11

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