CN104023759B - 用于镁植入物材料上的生物相容性等离子体电解涂层的贫电解质 - Google Patents

用于镁植入物材料上的生物相容性等离子体电解涂层的贫电解质 Download PDF

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Publication number
CN104023759B
CN104023759B CN201280054582.0A CN201280054582A CN104023759B CN 104023759 B CN104023759 B CN 104023759B CN 201280054582 A CN201280054582 A CN 201280054582A CN 104023759 B CN104023759 B CN 104023759B
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China
Prior art keywords
implant
coating
magnesium
bone
ceramic layer
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN201280054582.0A
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English (en)
Chinese (zh)
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CN104023759A (zh
Inventor
T.伊姆温克里伊德
P.库泽
S.贝克
D.巴纳杰
T.施瓦兹
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Synthes USA LLC
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Synthes USA LLC
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8085—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with pliable or malleable elements or having a mesh-like structure, e.g. small strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/086—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/022—Anodisation on selected surface areas
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/026—Anodisation with spark discharge
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02—Anodisation
    • C25D11/30—Anodisation of magnesium or alloys based thereon
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/36—Phosphatising
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D3/00—Electroplating: Baths therefor
    • C25D3/02—Electroplating: Baths therefor from solutions
    • C25D3/54—Electroplating: Baths therefor from solutions of metals not provided for in groups C25D3/04 - C25D3/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
CN201280054582.0A 2011-11-07 2012-11-07 用于镁植入物材料上的生物相容性等离子体电解涂层的贫电解质 Expired - Fee Related CN104023759B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161556563P 2011-11-07 2011-11-07
US61/556563 2011-11-07
PCT/US2012/063815 WO2013070669A1 (en) 2011-11-07 2012-11-07 Lean electrolyte for biocompatible plasmaelectrolytic coatings on magnesium implant material

Publications (2)

Publication Number Publication Date
CN104023759A CN104023759A (zh) 2014-09-03
CN104023759B true CN104023759B (zh) 2016-06-22

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CN201280054582.0A Expired - Fee Related CN104023759B (zh) 2011-11-07 2012-11-07 用于镁植入物材料上的生物相容性等离子体电解涂层的贫电解质

Country Status (11)

Country Link
US (2) US9066999B2 (enExample)
EP (1) EP2776083B1 (enExample)
JP (1) JP6177789B2 (enExample)
KR (1) KR102122707B1 (enExample)
CN (1) CN104023759B (enExample)
AU (1) AU2012335990B2 (enExample)
BR (1) BR112014010980B1 (enExample)
CA (1) CA2854667C (enExample)
IN (1) IN2014DN03158A (enExample)
TW (1) TWI569819B (enExample)
WO (1) WO2013070669A1 (enExample)

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EP3011979A4 (en) * 2013-06-18 2017-02-15 Olympus Corporation Implant for living organisms
JP2015085098A (ja) * 2013-11-01 2015-05-07 オリンパス株式会社 生体用インプラント
JP2015228906A (ja) * 2014-06-03 2015-12-21 オリンパス株式会社 骨接合用インプラント
JP2015229792A (ja) * 2014-06-05 2015-12-21 オリンパス株式会社 インプラントとその製造方法
JP6253528B2 (ja) * 2014-06-26 2017-12-27 オリンパス株式会社 インプラント
KR101695858B1 (ko) * 2015-07-14 2017-01-13 전북대학교산학협력단 생체 분해성 임플란트 및 이의 제조방법
WO2018134930A1 (ja) * 2017-01-19 2018-07-26 オリンパス株式会社 整形外科用インプラントおよびその製造方法
EP3981444A1 (en) * 2017-03-30 2022-04-13 Biomet Manufacturing, LLC Methods of modifying the porous surface of implants
KR102056844B1 (ko) 2018-04-19 2019-12-17 조선대학교산학협력단 전해질 조성물과 그 조성물을 이용하는 플라즈마 전해 산화 공정이 포함된 임플란트 제조방법
CN110585481B (zh) * 2019-08-28 2021-12-17 华南师范大学 一种针对脊柱损伤修复的纳米氢氧化镁区域性涂布聚乳酸-己内酯支架的制备及应用
CN113373491B (zh) * 2020-12-15 2024-07-09 北京航空航天大学 一种类牙釉质结构复合材料的制备方法
CN116940390A (zh) * 2021-02-03 2023-10-24 博恩解决方案有限公司 用于骨科植入物的镁基多孔涂层
DE102021103786B4 (de) 2021-02-17 2023-07-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Implantat zum Implantieren in einen Organismus und Verfahren
CN116098691B (zh) * 2022-12-30 2025-10-10 沪创医疗科技（上海）有限公司 可降解镁金属颅骨固定系统

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CN1069083A (zh) * 1991-07-15 1993-02-17 技术应用集团股份有限公司 镁制品的电化学二步涂覆法
CN1388272A (zh) * 2002-04-27 2003-01-01 上海金属腐蚀与防护技术有限公司 镁合金表面复合陶瓷质膜和生成方法
CN101040066A (zh) * 2004-07-23 2007-09-19 坎梅陶尔股份有限公司 在由可阳极氧化金属或合金制成的物品上形成高抗腐蚀性硬涂层的方法
US20100131052A1 (en) * 2008-11-21 2010-05-27 Gerhard Kappelt Method for producing a corrosion-inhibiting coating on an implant made of a biocorrodible magnesium alloy and implant produced according to the method
CN101871119A (zh) * 2010-07-28 2010-10-27 哈尔滨工业大学 一种镁合金表面微弧氧化/喷涂复合膜的制备方法

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US20150258252A1 (en) 2015-09-17
JP2015502193A (ja) 2015-01-22
JP6177789B2 (ja) 2017-08-09
WO2013070669A1 (en) 2013-05-16
KR20140091579A (ko) 2014-07-21
KR102122707B1 (ko) 2020-06-29
EP2776083B1 (en) 2017-07-26
EP2776083A1 (en) 2014-09-17
IN2014DN03158A (enExample) 2015-05-22
AU2012335990B2 (en) 2016-03-24
TW201334816A (zh) 2013-09-01
AU2012335990A1 (en) 2014-05-29
CA2854667A1 (en) 2013-05-16
CA2854667C (en) 2021-03-30
US9682176B2 (en) 2017-06-20
CN104023759A (zh) 2014-09-03
US9066999B2 (en) 2015-06-30
BR112014010980A2 (pt) 2017-06-06
TWI569819B (zh) 2017-02-11
BR112014010980B1 (pt) 2019-09-24
US20130116696A1 (en) 2013-05-09

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