CN103874727B - 注塑的剂型 - Google Patents

注塑的剂型 Download PDF

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Publication number
CN103874727B
CN103874727B CN201280050229.5A CN201280050229A CN103874727B CN 103874727 B CN103874727 B CN 103874727B CN 201280050229 A CN201280050229 A CN 201280050229A CN 103874727 B CN103874727 B CN 103874727B
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CN
China
Prior art keywords
composition
polysaccharide
shell
weight
dosage form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280050229.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN103874727A (zh
Inventor
M.D.里德
K.A.科彭斯
M.J.哈尔
J.赵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Global Technologies LLC
Original Assignee
Dow Global Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC filed Critical Dow Global Technologies LLC
Publication of CN103874727A publication Critical patent/CN103874727A/zh
Application granted granted Critical
Publication of CN103874727B publication Critical patent/CN103874727B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0016—Plasticisers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/05—Alcohols; Metal alcoholates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/286—Alkyl ethers substituted with acid radicals, e.g. carboxymethyl cellulose [CMC]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
CN201280050229.5A 2011-10-12 2012-10-09 注塑的剂型 Expired - Fee Related CN103874727B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161546242P 2011-10-12 2011-10-12
US61/546,242 2011-10-12
PCT/US2012/059323 WO2013055668A1 (en) 2011-10-12 2012-10-09 Injection-molded dosage form

Publications (2)

Publication Number Publication Date
CN103874727A CN103874727A (zh) 2014-06-18
CN103874727B true CN103874727B (zh) 2016-05-11

Family

ID=47144117

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280050229.5A Expired - Fee Related CN103874727B (zh) 2011-10-12 2012-10-09 注塑的剂型

Country Status (8)

Country Link
US (1) US9649278B2 (enExample)
EP (1) EP2766423A1 (enExample)
JP (1) JP6267125B2 (enExample)
KR (1) KR20140076621A (enExample)
CN (1) CN103874727B (enExample)
BR (1) BR112014003386A2 (enExample)
IN (1) IN2014CN02610A (enExample)
WO (1) WO2013055668A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550065B (zh) * 2013-10-26 2015-01-28 中山市凯博思淀粉材料科技有限公司 一种复合挤出法生产淀粉基软胶囊的方法
CN103520133B (zh) * 2013-10-26 2015-02-04 中山市凯博思淀粉材料科技有限公司 一种淀粉基软胶囊的制备方法
CN103495176B (zh) * 2013-10-26 2015-01-28 中山市凯博思淀粉材料科技有限公司 一种共混挤出法制备淀粉基软胶囊的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1720903A (zh) * 2005-06-20 2006-01-18 宁江松 一种带孔胶囊及其制备方法
CN1953739A (zh) * 2004-03-12 2007-04-25 史密斯克莱·比奇曼公司 药物制剂
CN101917978A (zh) * 2007-11-08 2010-12-15 葛兰素集团有限公司 药物制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526683A (en) 1946-04-13 1950-10-24 Lilly Co Eli Methyl cellulose capsules and process of manufacture
US4790881A (en) 1982-03-26 1988-12-13 Warner-Lambert Company Molded hydrophilic polymer
US4645812A (en) 1983-02-28 1987-02-24 Henkel Corporation Method of suspension polymerization of vinyl chloride
US4576284A (en) 1983-12-02 1986-03-18 Warner-Lambert Company Closing of filled capsules
US4738724A (en) 1983-11-04 1988-04-19 Warner-Lambert Company Method for forming pharmaceutical capsules from starch compositions
US4738817A (en) 1983-11-17 1988-04-19 Warner-Lambert Company Method for forming pharmaceutical capsules from hydrophilic polymers
TW207987B (enExample) 1991-03-20 1993-06-21 Hoechst Ag
US20050175687A1 (en) 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US6752953B2 (en) 2001-12-03 2004-06-22 Yung Shin Pharmaceutical Co., Ltd. Method for manufacturing hard non-gelatin pharmaceutical capsules
EP1396263A1 (en) * 2002-08-09 2004-03-10 Warner-Lambert Company Film coating for tablets and caplets
TW200526274A (en) * 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
KR20090094076A (ko) * 2006-10-20 2009-09-03 맥네일-피피씨, 인코포레이티드 아세트아미노펜／이부프로펜 병용물
EP2104493A2 (en) 2007-01-16 2009-09-30 Egalet A/S Use of i) a polyglycol and n) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse
US20090074944A1 (en) 2007-09-18 2009-03-19 Viva Pharmaceuticals Inc. Enteric coatings for orally ingestible compositions
JP2010540547A (ja) * 2007-09-28 2010-12-24 ノバルティス アーゲー アリスキレンおよびバルサルタンのガレヌス製剤
CN101827572A (zh) * 2007-10-15 2010-09-08 葛兰素集团有限公司 用于释放药物组合物的有板条的胶囊壳

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1953739A (zh) * 2004-03-12 2007-04-25 史密斯克莱·比奇曼公司 药物制剂
CN1720903A (zh) * 2005-06-20 2006-01-18 宁江松 一种带孔胶囊及其制备方法
CN101917978A (zh) * 2007-11-08 2010-12-15 葛兰素集团有限公司 药物制剂

Also Published As

Publication number Publication date
WO2013055668A1 (en) 2013-04-18
CN103874727A (zh) 2014-06-18
JP2014532069A (ja) 2014-12-04
KR20140076621A (ko) 2014-06-20
BR112014003386A2 (pt) 2017-03-01
US9649278B2 (en) 2017-05-16
JP6267125B2 (ja) 2018-01-24
IN2014CN02610A (enExample) 2015-08-07
EP2766423A1 (en) 2014-08-20
US20140271833A1 (en) 2014-09-18

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Granted publication date: 20160511

Termination date: 20181009

CF01 Termination of patent right due to non-payment of annual fee