CN103858007B - 用于预测对癌症治疗的敏感性的生物标记 - Google Patents

用于预测对癌症治疗的敏感性的生物标记 Download PDF

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CN103858007B
CN103858007B CN201280027029.8A CN201280027029A CN103858007B CN 103858007 B CN103858007 B CN 103858007B CN 201280027029 A CN201280027029 A CN 201280027029A CN 103858007 B CN103858007 B CN 103858007B
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methyl
piperazin
dihydro
pyrimidin
akt
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CN103858007A (zh
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K.林
E.庞努斯
S.塞沙吉里
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Genentech Inc
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Genentech Inc
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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CN201280027029.8A 2011-04-01 2012-03-30 用于预测对癌症治疗的敏感性的生物标记 Active CN103858007B (zh)

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Application Number Priority Date Filing Date Title
US201161471036P 2011-04-01 2011-04-01
US61/471,036 2011-04-01
PCT/US2012/031662 WO2012135749A2 (en) 2011-04-01 2012-03-30 Biomarkers for predicting sensitivity to cancer treatments

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CN103858007A CN103858007A (zh) 2014-06-11
CN103858007B true CN103858007B (zh) 2017-03-29

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US (4) US20140031259A1 (https=)
EP (2) EP2694959B8 (https=)
JP (4) JP6293655B2 (https=)
KR (2) KR102165122B1 (https=)
CN (1) CN103858007B (https=)
AU (1) AU2012236134A1 (https=)
BR (1) BR112013025356B1 (https=)
CA (1) CA2850175C (https=)
ES (1) ES2768081T3 (https=)
IL (1) IL228636A0 (https=)
MX (1) MX348655B (https=)
PL (1) PL2694959T3 (https=)
RU (1) RU2635193C2 (https=)
SG (2) SG10201507582VA (https=)
WO (1) WO2012135749A2 (https=)

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US20170290849A1 (en) * 2014-09-05 2017-10-12 The Trustees Of Columbia University In The City Of New York AKT and SHH Pathway Inhibitor Combination Therapy for Treating Basal Cell Carcinomas
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WO2020252455A1 (en) * 2019-06-13 2020-12-17 The General Hospital Corporation Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells
CA3189601A1 (en) 2020-07-24 2022-01-27 The General Hospital Corporation Enhanced virus-like particles and methods of use thereof for delivery to cells
CN113025713B (zh) * 2021-02-23 2022-11-22 浙江东睿生物科技有限公司 用于预测肿瘤患者对特定抗肿瘤药物的敏感性的生物标志物的应用

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