CN103800914A - Sweet orange-flavored traditional Chinese medicine mate - Google Patents

Sweet orange-flavored traditional Chinese medicine mate Download PDF

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CN103800914A
CN103800914A CN201410054974.8A CN201410054974A CN103800914A CN 103800914 A CN103800914 A CN 103800914A CN 201410054974 A CN201410054974 A CN 201410054974A CN 103800914 A CN103800914 A CN 103800914A
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chinese medicine
traditional chinese
citric acid
malic acid
fructus citri
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CN103800914B (en
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李学林
刘瑞新
张璐
康冰亚
施钧瀚
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FIRST AFFILIATED HOSPITAL OF HENAN INSTITUTE OF CHINESE MEDICINE
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Abstract

The invention relates to a sweet orange-flavored traditional Chinese medicine mate capable of solving the problem that the traditional Chinese medicine decoction is bitter and astringent in mouth feel and odorous in smell. A method is as follows: the sweet orange-flavored traditional Chinese medicine mate is prepared from the following raw materials in percentage by weight: 50-70 percent of sucrose, 0.05-0.1 percent of sucralose, 2-5 percent of sweet orange fruit powder, 0.5-1 percent of citric acid, 0.25-0.5 percent of malic acid, 22-50 percent of beta-cyclodextrin, 0.1-0.5 percent of orange essence and 0.01-0.05 percent of sweet orange essence, wherein the sucrose, the citric acid and the malic acid are crushed; the sucralose is uniformly mixed with the citric acid, the malic acid and the sweet orange fruit powder through an equivalent incremental method, then uniformly mixed with sucrose powder and the beta-cyclodextrin, dried at the temperature of 55 DEG C to 65 DEG C, cooling to the room temperature of 18 DEG C to 25 DEG C, added with the orange essence and the sweet orange essence and uniformly mixed to obtain the sweet orange-flavored traditional Chinese medicine mate. The sweet orange-flavored traditional Chinese medicine mate is eaten after being blended with the traditional Chinese medicine decoction or Chinese medicinal granules, so that the odorous taste of the traditional Chinese medicine decoction can be eliminated and the traditional Chinese medicine decoction is sweet and palatable in taste; therefore, the sweet orange-flavored traditional Chinese medicine mate not only is a nutriment easy to be digested and absorbed by human body but also improves the odorous taste of the traditional Chinese medicine, is convenient to be taken by a patient and beneficial to health, and also can be taken independently and increase the nutritional ingredients of the human body.

Description

Fructus Citri sinensis taste traditional Chinese medicine mate
Technical field
The present invention relates to solid beverage nutritious food, a kind of Fructus Citri sinensis taste traditional Chinese medicine mate of especially following Chinese medicine to take.
Background technology
Chinese medicine decoction is that China applies the earliest dosage form the most widely, can, with card plus-minus medicine, embody the marrow that the traditional Chinese medical science is cured the disease.Since 21 century, the consciousness of " back to nature, recover one's original simplicity " is rooted in the hearts of the people more, and Chinese medicine " correspondence between man and universe " theory that decoction embodies is favored more.But, many drawbacks of Chinese medicine decoction as preparation with carry serious its application of restriction such as inconvenience, mouthfeel is poor.Decoction agent for many years changes to take certain effect, and as single granule, boil medicine packaging facilities etc. has improved to a certain extent Chinese medicine decoction preparation and carried inconvenient drawback automatically, but the bad mouthfeel of Chinese medicine decoction is effectively improved.Have no need for reticence, " good medicine tastes bitter " become the biggest obstacle of restriction Chinese medicine compound decoction application already, and realizing " good medicine is no longer bitter to the taste " is the only way of realizing the modernization of Chinese medicine.Keeping under the former medicable prerequisite of decoction, by safety, easy, economic, feasible method, realize " good medicine is not bitter ", even " good medicine is tasty and refreshing ", will be very effective, necessary and urgent, and this is for improving patient's compliance, adapt to the health idea that modern people prevent and cure diseases, improve Chinese medicine decoction usage ratio, improve the reputation of Chinese medicine, promotion Chinese medicine modernization etc. is of great significance.Therefore, develop a kind of bad smell that can improve Chinese medicine decoction, be convenient to the traditional Chinese medicine mate that Chinese medicine decoction is taken by extensive patients, become urgent problem.
Summary of the invention
For above-mentioned situation, for overcoming the defect of prior art, the present invention's object is just to provide a kind of Fructus Citri sinensis taste traditional Chinese medicine mate, can effectively solve the problem of Chinese medicine decoction mouthfeel hardship, puckery and bad smell.
The technical scheme that the present invention solves is that this traditional Chinese medicine mate is to be made up of the raw material of following weight percent meter: sucrose 50-70%, sucralose 0.05-0.1%, Fructus Citri sinensis fruit powder 2-5%, citric acid 0.5-1%, malic acid 0.25-0.5%, beta-schardinger dextrin-22-50%, flavoring orange essence 0.1-0.5% and orange flavor 0.01-0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 55-65 ℃, be cooled to room temperature 18-25 ℃, add flavoring orange essence, orange flavor, mix homogeneously, subpackage.
It is edible after the present invention and Chinese medicine decoction or Chinese medicinal granule are in harmonious proportion, each 7g, can remove the poor taste of Chinese medicine decoction, make taste fragrant and sweet agreeable to the taste, be not only a kind of nutriment that human body is digested and assimilated that is easy to, improve again the bad mouthfeel of Chinese medicine, facilitate patients, also can take separately, increase the nutritional labeling of human body, be beneficial to healthy.
The specific embodiment
Below in conjunction with embodiment, the specific embodiment of the present invention is illustrated.
Embodiment 1
The present invention is in concrete enforcement, and this traditional Chinese medicine mate is to be made up of the raw material of following weight percent meter: sucrose 55%, sucralose 0.06%, Fructus Citri sinensis fruit powder 3%, citric acid 0.6%, malic acid 0.35%, beta-schardinger dextrin-40.76%, flavoring orange essence 0.2% and orange flavor 0.03%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 55 ℃, be cooled to 18 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, every bag 7g.
Embodiment 2
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percent meter: sucrose 60%, sucralose 0.07%, Fructus Citri sinensis fruit powder 4%, citric acid 0.7%, malic acid 0.4%, beta-schardinger dextrin-34.49%, flavoring orange essence 0.3% and orange flavor 0.04%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 60 ℃, be cooled to 22 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, every bag 7g.
Embodiment 3
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percent meter: sucrose 65%, sucralose 0.09%, Fructus Citri sinensis fruit powder 5%, citric acid 0.9%, malic acid 0.3%, beta-schardinger dextrin-28.24%, flavoring orange essence 0.45% and orange flavor 0.02%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 65 ℃, be cooled to 25 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, every bag 7g.
Embodiment 4
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percent meter: sucrose 70%, sucralose 0.1%, Fructus Citri sinensis fruit powder 5%, citric acid 1%, malic acid 0.5%, beta-schardinger dextrin-22.85%, flavoring orange essence 0.5% and orange flavor 0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 65 ℃, be cooled to 25 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, every bag 7g.
Embodiment 5
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percent meter: sucrose 50%, sucralose 0.05%, Fructus Citri sinensis fruit powder 2%, citric acid 0.5%, malic acid 0.25%, beta-schardinger dextrin-47.09%, flavoring orange essence 0.1% and orange flavor 0.01%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 63 ℃, be cooled to 24 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, every bag 7g.
The present invention after tested, protein, aminoacid, sugar and the polysaccharide, fat, mineral and the multivitamin that contain needed by human, edible after following Chinese medicine decoction or Chinese medicinal granule to be in harmonious proportion, can effectively remove the poor taste of Chinese medicine decoction, make taste fragrant and sweet agreeable to the taste, be not only a kind of nutriment that human body is digested and assimilated that is easy to, improve again the bad mouthfeel of Chinese medicine, facilitate patients, relevant experimental data is as follows:
1. Chinese medicine is divided into 5 grades by bitter degree, concrete following table:
The bad flavour hardship of Chinese medicine degree value ( i) qualitative description and quantitative scope
Figure 2014100549748100002DEST_PATH_IMAGE002A
2. the preparation of sample
Get Chinese medicinal granule composition " the stagnant soup of heat clearing awayization " by the clinical conventional prescription of the pharmacist of Chinese medicine " the stagnant soup of heat clearing awayization ", one pair of medicine rushes 120ml solution and obtains bitterness sample " the stagnant soup of heat clearing awayization ".
The stagnant soup formula of heat clearing awayization: Radix Bupleuri 18g, Radix Scutellariae 10g, Radix Puerariae 10g, Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 10g, Cortex Magnoliae Officinalis 6g, Semen Arecae 10g, Semen Coicis 30g, Rhizoma Et Radix Notopterygii 6g, Fructus Aurantii Immaturus 6g, Radix Glycyrrhizae 9g.
3. valuation officer's screening
After the examination and approval of Ethics Committee of No.1 Hospital Attached to He'nan Traditional Chinese Medical College, seminar has carried out including the strict screening bitterness sensitivity etc. the volunteer who recruits, 16 healthy volunteers are as experimenter in final selection, before test, sign Informed Consent Form, through training the qualified valuation officer of being decided to be.
4. test method
First surveying reference liquid first gets the 30 negative reference solutions of mL (purified water) and tastes in dixie cup in mouth, contained in mouth by valuation officer, timing 15s, the oral cavity action of gargling around here, so that the bitterness of sample can be experienced in the bitterness receptive field of the root of the tongue and tongue side, and be apprised of bitter degree classification and the concrete bitter degree value of this solution, spue, gargle 5 times, in oral cavity without bitterness.
The assay method of sample is measured with reference solution.One group of sample to valuation officer, taste impression according to mouth, according to the taste degree to sample, sample is sorted, and in conjunction with the contrast of reference solution, first bitter degree grade is determined in the statement of the bitterness in reference table, gives a concrete bitter degree value to tasted sample, in " the bitter taste of drug description list " recording and design in advance, each sample has been surveyed and has been gargled 5 times, in oral cavity without bitterness, after 2min, measure another sample.In addition,, when subject is to sample test in experiment, adopt random, single blind method to test sample.
The rejecting of 4.2 exceptional values
Now carrying out spearman check according to ranking results according to GBT 12315-2008 method evaluates valuation officer's performance, valuation officer's evaluating data of correlation coefficient r value less than 0.5 is all rejected, and residue valuation officer data adopt Grubbs method of inspection data to be carried out to circular test and the rejecting of exceptional value according to appraisal result.And take two-sided test, the mode of significant level 0.05 is rejected outlier, each is organized each and takes turns and only reject an exceptional value.And after rejecting, no longer carry out interpolation or supplement test.
5. result
" the stagnant soup of heat clearing awayization " bitter degree value average out to 3.2 ± 0.9, after adding the present invention, bitter degree value is reduced to 1.6 ± 0.6(P<0.01), the original bitterness of decoction and strange taste are covered to a great extent, added the sour-sweet mouthfeel of Fructus Citri sinensis simultaneously, make medicine mouthfeel approach orange juice, be more easily accepted.
Therefore, traditional Chinese medicine mate of the present invention and other Chinese medicine decoction or granule and other dosage form are followed and are taken, all obtain good useful technique effect, its experimental technique is with " the stagnant soup of heat clearing awayization ", tired stating no longer one by one, by experimental result and test, the present invention not only has the nutrient substance of needed by human, and have good flavored action, and follow Chinese medicine to take, can increase patient's nutrition, can give full play to again drug effect, being very beneficial for Rehabilitation, is to take the good companion of Chinese medicine, and economic and social benefit is remarkable.

Claims (6)

1. a Fructus Citri sinensis taste traditional Chinese medicine mate, it is characterized in that, made by the raw material of following weight percent meter: sucrose 50-70%, sucralose 0.05-0.1%, Fructus Citri sinensis fruit powder 2-5%, citric acid 0.5-1%, malic acid 0.25-0.5%, beta-schardinger dextrin-22-50%, flavoring orange essence 0.1-0.5% and orange flavor 0.01-0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, dry at 55-65 ℃, be cooled to room temperature 18-25 ℃, add flavoring orange essence, orange flavor, mix homogeneously.
2. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, made by the raw material of following weight percent meter: sucrose 55%, sucralose 0.06%, Fructus Citri sinensis fruit powder 3%, citric acid 0.6%, malic acid 0.35%, beta-schardinger dextrin-40.76%, flavoring orange essence 0.2% and orange flavor 0.03%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 55 ℃, be cooled to 18 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously.
3. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, made by the raw material of following weight percent meter: sucrose 60%, sucralose 0.07%, Fructus Citri sinensis fruit powder 4%, citric acid 0.7%, malic acid 0.4%, beta-schardinger dextrin-34.49%, flavoring orange essence 0.3% and orange flavor 0.04%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 60 ℃, be cooled to 22 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously.
4. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, made by the raw material of following weight percent meter: sucrose 65%, sucralose 0.09%, Fructus Citri sinensis fruit powder 5%, citric acid 0.9%, malic acid 0.3%, beta-schardinger dextrin-28.24%, flavoring orange essence 0.45% and orange flavor 0.02%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 65 ℃, be cooled to 25 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously.
5. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, made by the raw material of following weight percent meter: sucrose 70%, sucralose 0.1%, Fructus Citri sinensis fruit powder 5%, citric acid 1%, malic acid 0.5%, beta-schardinger dextrin-22.85%, flavoring orange essence 0.5% and orange flavor 0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 65 ℃, be cooled to 25 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously.
6. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, made by the raw material of following weight percent meter: sucrose 50%, sucralose 0.05%, Fructus Citri sinensis fruit powder 2%, citric acid 0.5%, malic acid 0.25%, beta-schardinger dextrin-47.09%, flavoring orange essence 0.1% and orange flavor 0.01%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder with equivalent incremental method, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, be dried at 63 ℃, be cooled to 24 ℃ of room temperatures, add flavoring orange essence, orange flavor, mix homogeneously.
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Cited By (9)

* Cited by examiner, † Cited by third party
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CN105725018A (en) * 2016-01-30 2016-07-06 山西大学 Sugar-free L-calcium lactate drink and preparation method thereof
CN105816528A (en) * 2016-03-23 2016-08-03 四川好医生药业集团有限公司 Exterior syndrome relieving granules for children with taste improved and preparing method thereof
CN107348419A (en) * 2017-08-25 2017-11-17 云南省药物研究所 A kind of haw taste pseudo-ginseng companion
CN108094805A (en) * 2018-01-26 2018-06-01 河南中医药大学第附属医院 A kind of milk flavor traditional Chinese medicine mate
CN110585438A (en) * 2019-10-22 2019-12-20 湖南焱医堂中医药产业有限公司 Sugar-free Chinese medicinal mate
CN110585119A (en) * 2019-09-30 2019-12-20 河南中医药大学第一附属医院 Jelly type traditional Chinese medicine mate
CN112472811A (en) * 2021-01-14 2021-03-12 河南中医药大学第一附属医院 Sugar-free Chinese medicinal effervescent tablet and its preparation method
CN112870372A (en) * 2021-04-09 2021-06-01 陕西中财润德医药科技有限公司 Traditional Chinese medicine composition for improving bad taste of traditional Chinese medicine decoction and preparation method
CN114712314A (en) * 2022-03-10 2022-07-08 河南中医药大学第一附属医院 Chinese gooseberry-flavored traditional Chinese medicine mate particles and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102166034A (en) * 2010-11-23 2011-08-31 天津市尖峰天然产物研究开发有限公司 Solid beverage for seasoning tea powder and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102166034A (en) * 2010-11-23 2011-08-31 天津市尖峰天然产物研究开发有限公司 Solid beverage for seasoning tea powder and preparation method thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105725018A (en) * 2016-01-30 2016-07-06 山西大学 Sugar-free L-calcium lactate drink and preparation method thereof
CN105816528A (en) * 2016-03-23 2016-08-03 四川好医生药业集团有限公司 Exterior syndrome relieving granules for children with taste improved and preparing method thereof
CN105816528B (en) * 2016-03-23 2018-12-25 四川好医生药业集团有限公司 Improve the Xiaoerjiebiao granules and preparation method thereof of mouthfeel
CN107348419A (en) * 2017-08-25 2017-11-17 云南省药物研究所 A kind of haw taste pseudo-ginseng companion
CN108094805A (en) * 2018-01-26 2018-06-01 河南中医药大学第附属医院 A kind of milk flavor traditional Chinese medicine mate
CN110585119A (en) * 2019-09-30 2019-12-20 河南中医药大学第一附属医院 Jelly type traditional Chinese medicine mate
CN110585438A (en) * 2019-10-22 2019-12-20 湖南焱医堂中医药产业有限公司 Sugar-free Chinese medicinal mate
CN112472811A (en) * 2021-01-14 2021-03-12 河南中医药大学第一附属医院 Sugar-free Chinese medicinal effervescent tablet and its preparation method
CN112870372A (en) * 2021-04-09 2021-06-01 陕西中财润德医药科技有限公司 Traditional Chinese medicine composition for improving bad taste of traditional Chinese medicine decoction and preparation method
CN114712314A (en) * 2022-03-10 2022-07-08 河南中医药大学第一附属医院 Chinese gooseberry-flavored traditional Chinese medicine mate particles and preparation method thereof

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