CN103800914B - Fructus Citri sinensis taste traditional Chinese medicine mate - Google Patents
Fructus Citri sinensis taste traditional Chinese medicine mate Download PDFInfo
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- CN103800914B CN103800914B CN201410054974.8A CN201410054974A CN103800914B CN 103800914 B CN103800914 B CN 103800914B CN 201410054974 A CN201410054974 A CN 201410054974A CN 103800914 B CN103800914 B CN 103800914B
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Abstract
The present invention relates to Fructus Citri sinensis taste traditional Chinese medicine mate, effectively can solve the problem of bitter, the puckery and bad smell of Chinese medicine decoction mouthfeel, method is, is made up of the raw material of following weight percent meter: sucrose 50-70%, sucralose 0.05-0.1%, Fructus Citri sinensis fruit powder 2-5%, citric acid 0.5-1%, malic acid 0.25-0.5%, beta-schardinger dextrin-22-50%, flavoring orange essence 0.1-0.5% and orange flavor 0.01-0.05%, wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method and citric acid, malic acid and Fructus Citri sinensis fruit powder mix homogeneously, again with cane sugar powder, beta-schardinger dextrin-mix homogeneously, 55-65 DEG C of drying, be cooled to room temperature 18-25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, it is edible after the present invention and Chinese medicine decoction or Chinese medicinal granule are in harmonious proportion, the poor taste of Chinese medicine decoction can be removed, make taste fragrant and sweet agreeable to the taste, be not only a kind of nutriment being easy to human consumption and absorbing, improve again the bad mouthfeel of Chinese medicine, facilitate patients, also can take separately, increase the nutritional labeling of human body, be beneficial to healthy.
Description
Technical field
The present invention relates to solid beverage nutritious food, especially with a kind of Fructus Citri sinensis taste traditional Chinese medicine mate that Chinese medicine is taken.
Background technology
Chinese medicine decoction is that China applies the earliest dosage form the most widely, with card plus-minus medicine, can embody the marrow that the traditional Chinese medical science is cured the disease.Since 21 century, the consciousness of " back to nature, recover one's original simplicity " is rooted in the hearts of the people more, and Chinese medicine " correspondence between man and universe " theory that decoction embodies is favored more.But, many drawbacks of Chinese medicine decoction as preparation with carry inconvenience, mouthfeel difference etc. and seriously restrict it and apply.Decoction agent for many years changes and achieves certain effect, and as single granule, automatically packaging facilities etc. of boiling medicine improve Chinese medicine decoction preparation and the drawback of carrying inconvenience to a certain extent, but the bad mouthfeel of Chinese medicine decoction is effectively improved.Have no need for reticence, " good medicine tastes bitter " had become the biggest obstacle of restriction Chinese medicine compound decoction application already, and realizing " good medicine is no longer bitter to the taste " is the only way realizing the modernization of Chinese medicine.Under the former medicable prerequisite of maintenance decoction, by safety, easy, economic, feasible method, realize " good medicine is not bitter ", even " good medicine is tasty and refreshing ", will be very effective, necessary and urgent, this be for raising patient medication compliance, adapt to the health idea that modern people prevent and cure diseases, improve Chinese medicine decoction usage ratio, improve the reputation of Chinese medicine, promote TCM Modernization process etc. and be of great significance.Therefore, develop a kind of bad smell that can improve Chinese medicine decoction, be convenient to the traditional Chinese medicine mate that Chinese medicine decoction is taken by extensive patients, become urgent problem.
Summary of the invention
For above-mentioned situation, for overcoming the defect of prior art, the object of the present invention is just to provide a kind of Fructus Citri sinensis taste traditional Chinese medicine mate, effectively can solve the problem of bitter, the puckery and bad smell of Chinese medicine decoction mouthfeel.
The technical scheme that the present invention solves is that this traditional Chinese medicine mate is made up of the raw material of following weight percent meter: sucrose 50-70%, sucralose 0.05-0.1%, Fructus Citri sinensis fruit powder 2-5%, citric acid 0.5-1%, malic acid 0.25-0.5%, beta-schardinger dextrin-22-50%, flavoring orange essence 0.1-0.5% and orange flavor 0.01-0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 55-65 DEG C of drying, be cooled to room temperature 18-25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, subpackage.
It is edible after the present invention and Chinese medicine decoction or Chinese medicinal granule are in harmonious proportion, each 7g, the poor taste of Chinese medicine decoction can be removed, make taste fragrant and sweet agreeable to the taste, be not only a kind of nutriment being easy to human consumption and absorbing, improve again the bad mouthfeel of Chinese medicine, facilitate patients, also can take separately, increase the nutritional labeling of human body, be beneficial to healthy.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is illustrated.
Embodiment 1
The present invention is in concrete enforcement, and this traditional Chinese medicine mate is made up of the raw material of following weight percentage: sucrose 55%, sucralose 0.06%, Fructus Citri sinensis fruit powder 3%, citric acid 0.6%, malic acid 0.35%, beta-schardinger dextrin-40.76%, flavoring orange essence 0.2% and orange flavor 0.03%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 55 DEG C of dryings, be cooled to room temperature 18 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, often wraps 7g.
Embodiment 2
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percentage: sucrose 60%, sucralose 0.07%, Fructus Citri sinensis fruit powder 4%, citric acid 0.7%, malic acid 0.4%, beta-schardinger dextrin-34.49%, flavoring orange essence 0.3% and orange flavor 0.04%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 60 DEG C of dryings, be cooled to room temperature 22 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, often wraps 7g.
Embodiment 3
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percentage: sucrose 65%, sucralose 0.09%, Fructus Citri sinensis fruit powder 5%, citric acid 0.9%, malic acid 0.3%, beta-schardinger dextrin-28.24%, flavoring orange essence 0.45% and orange flavor 0.02%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 65 DEG C of dryings, be cooled to room temperature 25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, often wraps 7g.
Embodiment 4
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percentage: sucrose 70%, sucralose 0.1%, Fructus Citri sinensis fruit powder 5%, citric acid 1%, malic acid 0.5%, beta-schardinger dextrin-22.85%, flavoring orange essence 0.5% and orange flavor 0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 65 DEG C of dryings, be cooled to room temperature 25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, often wraps 7g.
Embodiment 5
The present invention is in concrete enforcement, and this traditional Chinese medicine mate also can be made up of the raw material of following weight percentage: sucrose 50%, sucralose 0.05%, Fructus Citri sinensis fruit powder 2%, citric acid 0.5%, malic acid 0.25%, beta-schardinger dextrin-47.09%, flavoring orange essence 0.1% and orange flavor 0.01%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 63 DEG C of dryings, be cooled to room temperature 24 DEG C, add flavoring orange essence, orange flavor, mix homogeneously, subpackage, often wraps 7g.
The present invention after tested, protein containing needed by human, aminoacid, sugar and polysaccharide, fat, mineral and multivitamin, edible after being in harmonious proportion with Chinese medicine decoction or Chinese medicinal granule, effectively can remove the poor taste of Chinese medicine decoction, make taste fragrant and sweet agreeable to the taste, be not only a kind of nutriment being easy to human consumption and absorbing, improve again the bad mouthfeel of Chinese medicine, facilitate patients, regarding assay data is as follows:
1. Chinese medicine is divided into 5 grades by bitter degree, concrete following table:
The bitter angle value of the bad flavour of Chinese medicine (
i) qualitative description and quantification range
2. the preparation of sample
Get Chinese medicinal granule composition " the stagnant soup of heat clearing awayization " by the clinical conventional prescription of the pharmacist of Chinese medicine " the stagnant soup of heat clearing awayization ", one pair of medicine rushes 120ml solution and namely obtains bitterness sample " the stagnant soup of heat clearing awayization ".
The stagnant soup formula of heat clearing awayization: Radix Bupleuri 18g, Radix Scutellariae 10g, Radix Puerariae 10g, Gypsum Fibrosum 30g, Rhizoma Anemarrhenae 10g, Cortex Magnoliae Officinalis 6g, Semen Arecae 10g, Semen Coicis 30g, Rhizoma Et Radix Notopterygii 6g, Fructus Aurantii Immaturus 6g, Radix Glycyrrhizae 9g.
3. valuation officer's screening
After the examination and approval of Ethics Committee of No.1 Hospital Attached to He'nan Traditional Chinese Medical College, seminar has carried out to the volunteer recruited the strict screening comprising bitterness sensitivity etc., final selection 16 healthy volunteers are as experimenter, signing Informed Consent Form before the test, being qualifiedly decided to be valuation officer through training.
4. test method
First survey reference liquid first to get 30mL negative reference solution (purified water) and taste in dixie cup in mouth, by valuation officer containing in mouth, timing 15s, gargle action in oral cavity around here, with the bitterness enabling the bitterness receptive field of the root of the tongue and tongue side experience sample, and be apprised of the bitter degree classification of this solution and concrete bitter angle value, spue, gargle 5 times, without bitterness to oral cavity.
Sample tests method measures with reference solution.One group of sample to valuation officer, impression is tasted according to mouth, according to the taste degree of sample, sample is sorted, and combine and the contrast of reference solution, bitter degree grade is determined in the bitterness statement first in reference table, gives a concrete bitter angle value to tasted sample, record is with " the bitter taste of drug description list " that design in advance, each sample has been surveyed and has been gargled 5 times, without bitterness to oral cavity, measures another sample after 2min.In addition, when subject is to sample test in experiment, random, single blind method is adopted to test sample.
The rejecting of 4.2 exceptional values
Now carry out spearman inspection according to ranking results according to GBT12315-2008 method to evaluate valuation officer's performance, the valuation officer evaluating data of correlation coefficient r value less than 0.5 is all rejected, and residue valuation officer data have carried out circular test and the rejecting of exceptional value to data according to appraisal result employing Grubbs method of inspection.And take two-sided test, the mode of significant level 0.05 is rejected outlier, and each is organized each and takes turns an only rejecting exceptional value.And no longer carry out interpolation after rejecting or supplement test.
5. result
" the stagnant soup of heat clearing awayization " bitter angle value average out to 3.2 ± 0.9, after adding the present invention, bitter angle value reduces to 1.6 ± 0.6(P<0.01), mask the original bitterness of decoction and strange taste to a great extent, add the sour-sweet mouthfeel of Fructus Citri sinensis simultaneously, make medicine mouthfeel close to orange juice, be more easily accepted.
Therefore, traditional Chinese medicine mate of the present invention and other Chinese medicine decoction or granule and other dosage form are with taking, all achieve good Advantageous Effects, its experimental technique is with " the stagnant soup of heat clearing awayization ", tire out no longer one by one and state, by experimental result and test, the present invention not only has the nutrient substance of needed by human, and have good flavored action, take with Chinese medicine, the nutrition of patient can be increased, drug effect can be given full play to again, be very beneficial for Rehabilitation, be take the good companion of Chinese medicine, economic and social benefit is remarkable.
Claims (6)
1. a Fructus Citri sinensis taste traditional Chinese medicine mate, it is characterized in that, be made up of the raw material of following weight percent meter: sucrose 50-70%, sucralose 0.05-0.1%, Fructus Citri sinensis fruit powder 2-5%, citric acid 0.5-1%, malic acid 0.25-0.5%, beta-schardinger dextrin-22-50%, flavoring orange essence 0.1-0.5% and orange flavor 0.01-0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 55-65 DEG C of drying, be cooled to room temperature 18-25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously.
2. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, be made up of the raw material of following weight percentage: sucrose 55%, sucralose 0.06%, Fructus Citri sinensis fruit powder 3%, citric acid 0.6%, malic acid 0.35%, beta-schardinger dextrin-40.76%, flavoring orange essence 0.2% and orange flavor 0.03%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 55 DEG C of dryings, be cooled to room temperature 18 DEG C, add flavoring orange essence, orange flavor, mix homogeneously.
3. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, be made up of the raw material of following weight percentage: sucrose 60%, sucralose 0.07%, Fructus Citri sinensis fruit powder 4%, citric acid 0.7%, malic acid 0.4%, beta-schardinger dextrin-34.49%, flavoring orange essence 0.3% and orange flavor 0.04%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 60 DEG C of dryings, be cooled to room temperature 22 DEG C, add flavoring orange essence, orange flavor, mix homogeneously.
4. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, be made up of the raw material of following weight percentage: sucrose 65%, sucralose 0.09%, Fructus Citri sinensis fruit powder 5%, citric acid 0.9%, malic acid 0.3%, beta-schardinger dextrin-28.24%, flavoring orange essence 0.45% and orange flavor 0.02%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 65 DEG C of dryings, be cooled to room temperature 25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously.
5. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, be made up of the raw material of following weight percentage: sucrose 70%, sucralose 0.1%, Fructus Citri sinensis fruit powder 5%, citric acid 1%, malic acid 0.5%, beta-schardinger dextrin-22.85%, flavoring orange essence 0.5% and orange flavor 0.05%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 65 DEG C of dryings, be cooled to room temperature 25 DEG C, add flavoring orange essence, orange flavor, mix homogeneously.
6. Fructus Citri sinensis taste traditional Chinese medicine mate according to claim 1, it is characterized in that, be made up of the raw material of following weight percentage: sucrose 50%, sucralose 0.05%, Fructus Citri sinensis fruit powder 2%, citric acid 0.5%, malic acid 0.25%, beta-schardinger dextrin-47.09%, flavoring orange essence 0.1% and orange flavor 0.01%; Wherein, sucrose, citric acid and malic acid are pulverized, and sucralose equal increments method is mixed homogeneously with citric acid, malic acid and Fructus Citri sinensis fruit powder, mix homogeneously with cane sugar powder, beta-schardinger dextrin-again, 63 DEG C of dryings, be cooled to room temperature 24 DEG C, add flavoring orange essence, orange flavor, mix homogeneously.
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| CN105725018A (en) * | 2016-01-30 | 2016-07-06 | 山西大学 | Sugar-free L-calcium lactate drink and preparation method thereof |
| CN105816528B (en) * | 2016-03-23 | 2018-12-25 | 四川好医生药业集团有限公司 | Improve the Xiaoerjiebiao granules and preparation method thereof of mouthfeel |
| CN107348419A (en) * | 2017-08-25 | 2017-11-17 | 云南省药物研究所 | A kind of haw taste pseudo-ginseng companion |
| CN108094805A (en) * | 2018-01-26 | 2018-06-01 | 河南中医药大学第附属医院 | A kind of milk flavor traditional Chinese medicine mate |
| CN110585119A (en) * | 2019-09-30 | 2019-12-20 | 河南中医药大学第一附属医院 | Jelly type traditional Chinese medicine mate |
| CN110585438A (en) * | 2019-10-22 | 2019-12-20 | 湖南焱医堂中医药产业有限公司 | Sugar-free Chinese medicinal mate |
| CN112472811A (en) * | 2021-01-14 | 2021-03-12 | 河南中医药大学第一附属医院 | Sugar-free Chinese medicinal effervescent tablet and its preparation method |
| CN112870372A (en) * | 2021-04-09 | 2021-06-01 | 陕西中财润德医药科技有限公司 | Traditional Chinese medicine composition for improving bad taste of traditional Chinese medicine decoction and preparation method |
| CN114712314A (en) * | 2022-03-10 | 2022-07-08 | 河南中医药大学第一附属医院 | Chinese gooseberry-flavored traditional Chinese medicine mate particles and preparation method thereof |
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Effective date of registration: 20180829 Address after: 450000 Henan free trade pilot area Zhengzhou area (Zheng Dong) business outer ring road 7, 14 level 1411. Patentee after: Henan ring Jia medicine food homology Biotechnology Co., Ltd. Address before: 450004 19 Renmin Road, Zhengzhou, Henan Patentee before: THE FIRST AFFILIATED HOSPITAL OF HENAN INSTITUTE OF CHINESE MEDICINE |
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