CN103764028B - 凝固控制剂和包含凝固控制剂的装置 - Google Patents

凝固控制剂和包含凝固控制剂的装置 Download PDF

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Publication number
CN103764028B
CN103764028B CN201280041036.3A CN201280041036A CN103764028B CN 103764028 B CN103764028 B CN 103764028B CN 201280041036 A CN201280041036 A CN 201280041036A CN 103764028 B CN103764028 B CN 103764028B
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CN
China
Prior art keywords
container
thrombin
blood
controlling agent
carboxylic acid
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CN201280041036.3A
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English (en)
Chinese (zh)
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CN103764028A (zh
Inventor
D·门罗
S·诺瓦拉
R·A·霍克
P·F·霍姆斯
J·杜达罗内克
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Becton Dickinson and Co
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Becton Dickinson and Co
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150473—Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physiology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201280041036.3A 2011-07-05 2012-07-02 凝固控制剂和包含凝固控制剂的装置 Active CN103764028B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161504496P 2011-07-05 2011-07-05
US61/504,496 2011-07-05
PCT/US2012/045243 WO2013006550A1 (en) 2011-07-05 2012-07-02 Coagulation controlling agents and devices comprising the same

Publications (2)

Publication Number Publication Date
CN103764028A CN103764028A (zh) 2014-04-30
CN103764028B true CN103764028B (zh) 2016-08-24

Family

ID=46545906

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280041036.3A Active CN103764028B (zh) 2011-07-05 2012-07-02 凝固控制剂和包含凝固控制剂的装置

Country Status (15)

Country Link
US (1) US9949473B2 (ru)
EP (1) EP2729068B1 (ru)
JP (2) JP6060156B2 (ru)
KR (1) KR102059120B1 (ru)
CN (1) CN103764028B (ru)
AU (1) AU2012279135B2 (ru)
BR (1) BR112014000144B1 (ru)
CA (1) CA2841088C (ru)
ES (1) ES2703512T3 (ru)
MX (1) MX347114B (ru)
MY (1) MY167803A (ru)
RU (1) RU2622760C9 (ru)
SG (1) SG10201605495UA (ru)
WO (1) WO2013006550A1 (ru)
ZA (1) ZA201400329B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL229134A0 (en) 2013-10-29 2014-03-31 Omrix Biopharmaceuticals Ltd Compounds and methods for stabilizing thrombin activity
KR102571662B1 (ko) * 2014-06-01 2023-08-25 데비오팜 인터네셔날 에스 에이 샘플 수집 및 가공 장치
CN106645721B (zh) * 2016-09-30 2018-10-09 广州鸿琪光学仪器科技有限公司 一种凝固酶检测试剂、反应垫、其制备方法及试剂盒
US20200269233A1 (en) * 2019-02-25 2020-08-27 Binyamin Baruch Lowenstein Modified Conical Centrifuge Tubes
EP4064837A4 (en) * 2019-11-29 2023-01-04 Rutgers, the State University of New Jersey COMPOSITIONS, KITS AND METHODS FOR STORING BLOOD PRODUCTS AND METHODS OF USE THEREOF
CN118284808A (zh) * 2022-03-25 2024-07-02 积水医疗株式会社 循环肿瘤细胞分离试剂盒、循环肿瘤细胞分离容器及循环肿瘤细胞的分离方法
US20240218344A1 (en) * 2022-12-23 2024-07-04 Instrumentation Laboratory Company Liquid thrombin reagent

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985026A (en) * 1988-08-03 1991-01-15 Terumo Kabushiki Kaisha Blood collecting tube
US5511558A (en) * 1994-06-06 1996-04-30 Becton, Dickinson And Company Blood collection assembly having additive dispensing means and method for sample collection using same
US5634474A (en) * 1995-04-28 1997-06-03 Becton, Dickinson And Company Blood collection assembly including clot-accelerating glass insert
CN1585654A (zh) * 2001-11-13 2005-02-23 贝克顿迪肯森公司 将抗凝血剂涂在注射器套筒上的喷雾干燥法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3902964A (en) * 1971-12-13 1975-09-02 U S Medical Research And Dev I Method of and apparatus for chemically separating plasma or serum from formed elements of blood
JPS5639782A (en) 1979-09-04 1981-04-15 Dai Ichi Pure Chem Co Ltd Stabilization of thrombin
JPS62253036A (ja) 1986-04-25 1987-11-04 テルモ株式会社 凝固促進剤入採血管
US4788139A (en) 1987-08-06 1988-11-29 Streck Laboratories, Inc. Platelet aggregation reagent, reagent container and method of determining platelet aggregation in EDTA-anticoagulated blood
JP2715104B2 (ja) * 1988-08-18 1998-02-18 株式会社ミドリ十字 トロンビン乾燥製剤
US4946601A (en) * 1988-08-22 1990-08-07 Sherwood Medical Company Blood serum separator tube
US5378431A (en) * 1993-06-14 1995-01-03 Becton, Dickinson And Company Dual pathway clotting enhancer for blood collection tube
US5556643A (en) * 1993-12-22 1996-09-17 Hydrite Chemical Co. Anticoagulant compositions
US5860937A (en) * 1997-04-30 1999-01-19 Becton, Dickinson & Company Evacuated sample collection tube with aqueous additive
US6534016B1 (en) 1997-04-30 2003-03-18 Richmond Cohen Additive preparation and method of use thereof
JP2000070241A (ja) 1998-08-31 2000-03-07 Nissho Corp 急速凝固用真空採血管
DE60008584T2 (de) 1999-12-08 2004-11-04 Ajinomoto Co., Inc. Benzamidin-derivate
EP2260942A3 (en) 2002-05-13 2011-03-09 Becton, Dickinson and Company Protease Inhibitor Sample Collection System
EP1580551B1 (en) * 2002-11-19 2013-02-20 Sekisui Medical Co., Ltd. Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane
CN1504580A (zh) 2002-11-28 2004-06-16 希森美康株式会社 凝血酶试剂以及检查试剂套装
JP2004191367A (ja) * 2002-11-28 2004-07-08 Sysmex Corp トロンビン試薬及び検査試薬キット
KR20060070536A (ko) * 2003-08-05 2006-06-23 벡톤 디킨슨 앤드 컴퍼니 생물학적 액체 샘플의 수집과 선택된 성분들의 처리를 위한장치 및 방법
JP2005265126A (ja) 2004-03-19 2005-09-29 Ntn Corp 総ころ型円錐ころ軸受
US7700046B2 (en) * 2004-09-14 2010-04-20 Goldenberg Alec S Controlled additive/reactant delivery system
JP4914115B2 (ja) 2006-05-12 2012-04-11 積水化学工業株式会社 血液検査用容器
CN101059521B (zh) 2007-05-30 2011-06-29 保定天岳生物工程有限公司 一种无需稀释血浆样本测定纤维蛋白原含量的试剂及其测定方法
WO2009110488A1 (ja) 2008-03-04 2009-09-11 テルモ株式会社 採血管
CA2734711C (en) 2008-08-28 2012-10-30 Sekisui Medical Co., Ltd. Blood collection container

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985026A (en) * 1988-08-03 1991-01-15 Terumo Kabushiki Kaisha Blood collecting tube
US5511558A (en) * 1994-06-06 1996-04-30 Becton, Dickinson And Company Blood collection assembly having additive dispensing means and method for sample collection using same
US5634474A (en) * 1995-04-28 1997-06-03 Becton, Dickinson And Company Blood collection assembly including clot-accelerating glass insert
CN1585654A (zh) * 2001-11-13 2005-02-23 贝克顿迪肯森公司 将抗凝血剂涂在注射器套筒上的喷雾干燥法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
p-Aminobenzamindine as a fluorescent probe for the active site of serine proteases;Susan A. Evans 等;《The Journal of Biological Chemistry》;19820325;第257卷(第6期);第3014-3017页 *

Also Published As

Publication number Publication date
BR112014000144A2 (pt) 2017-06-13
NZ619674A (en) 2015-06-26
JP2017075960A (ja) 2017-04-20
RU2014103327A (ru) 2015-08-10
EP2729068B1 (en) 2018-10-10
KR102059120B1 (ko) 2019-12-24
US20130183655A1 (en) 2013-07-18
MY167803A (en) 2018-09-26
AU2012279135B2 (en) 2017-05-25
US9949473B2 (en) 2018-04-24
MX347114B (es) 2017-04-12
RU2622760C2 (ru) 2017-06-19
CA2841088C (en) 2018-01-16
CA2841088A1 (en) 2013-01-10
JP2014524027A (ja) 2014-09-18
JP6392835B2 (ja) 2018-09-19
RU2622760C9 (ru) 2017-08-08
WO2013006550A1 (en) 2013-01-10
ES2703512T3 (es) 2019-03-11
EP2729068A1 (en) 2014-05-14
ZA201400329B (en) 2015-06-24
CN103764028A (zh) 2014-04-30
AU2012279135A1 (en) 2014-01-23
KR20140051281A (ko) 2014-04-30
BR112014000144B1 (pt) 2022-03-03
MX2014000152A (es) 2014-02-19
JP6060156B2 (ja) 2017-01-11
SG10201605495UA (en) 2016-09-29

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