CN103751682A - 一种治疗肺热咳嗽的药物及其制备方法 - Google Patents
一种治疗肺热咳嗽的药物及其制备方法 Download PDFInfo
- Publication number
- CN103751682A CN103751682A CN201410038493.8A CN201410038493A CN103751682A CN 103751682 A CN103751682 A CN 103751682A CN 201410038493 A CN201410038493 A CN 201410038493A CN 103751682 A CN103751682 A CN 103751682A
- Authority
- CN
- China
- Prior art keywords
- radix
- grams
- gram
- rhizoma
- clean
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 42
- 206010011224 Cough Diseases 0.000 title claims abstract description 38
- 229940079593 drugs Drugs 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 210000004072 Lung Anatomy 0.000 title abstract description 32
- 210000002216 Heart Anatomy 0.000 claims abstract description 10
- 238000004140 cleaning Methods 0.000 claims description 56
- 239000012535 impurity Substances 0.000 claims description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances data:image/svg+xml;base64,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 data:image/svg+xml;base64,PD94bWwgdmVyc2lvbj0nMS4wJyBlbmNvZGluZz0naXNvLTg4NTktMSc/Pgo8c3ZnIHZlcnNpb249JzEuMScgYmFzZVByb2ZpbGU9J2Z1bGwnCiAgICAgICAgICAgICAgeG1sbnM9J2h0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnJwogICAgICAgICAgICAgICAgICAgICAgeG1sbnM6cmRraXQ9J2h0dHA6Ly93d3cucmRraXQub3JnL3htbCcKICAgICAgICAgICAgICAgICAgICAgIHhtbG5zOnhsaW5rPSdodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rJwogICAgICAgICAgICAgICAgICB4bWw6c3BhY2U9J3ByZXNlcnZlJwp3aWR0aD0nODVweCcgaGVpZ2h0PSc4NXB4JyB2aWV3Qm94PScwIDAgODUgODUnPgo8IS0tIEVORCBPRiBIRUFERVIgLS0+CjxyZWN0IHN0eWxlPSdvcGFjaXR5OjEuMDtmaWxsOiNGRkZGRkY7c3Ryb2tlOm5vbmUnIHdpZHRoPSc4NS4wJyBoZWlnaHQ9Jzg1LjAnIHg9JzAuMCcgeT0nMC4wJz4gPC9yZWN0Pgo8dGV4dCB4PScxMy4zJyB5PSc1My42JyBjbGFzcz0nYXRvbS0wJyBzdHlsZT0nZm9udC1zaXplOjIzcHg7Zm9udC1zdHlsZTpub3JtYWw7Zm9udC13ZWlnaHQ6bm9ybWFsO2ZpbGwtb3BhY2l0eToxO3N0cm9rZTpub25lO2ZvbnQtZmFtaWx5OnNhbnMtc2VyaWY7dGV4dC1hbmNob3I6c3RhcnQ7ZmlsbDojRTg0MjM1JyA+SDwvdGV4dD4KPHRleHQgeD0nMjguMicgeT0nNjIuOScgY2xhc3M9J2F0b20tMCcgc3R5bGU9J2ZvbnQtc2l6ZToxNXB4O2ZvbnQtc3R5bGU6bm9ybWFsO2ZvbnQtd2VpZ2h0Om5vcm1hbDtmaWxsLW9wYWNpdHk6MTtzdHJva2U6bm9uZTtmb250LWZhbWlseTpzYW5zLXNlcmlmO3RleHQtYW5jaG9yOnN0YXJ0O2ZpbGw6I0U4NDIzNScgPjI8L3RleHQ+Cjx0ZXh0IHg9JzM1LjAnIHk9JzUzLjYnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6MjNweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5PPC90ZXh0Pgo8L3N2Zz4K O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- 241000628997 Flos Species 0.000 claims description 20
- 238000005202 decontamination Methods 0.000 claims description 18
- 230000003588 decontaminative Effects 0.000 claims description 18
- 241000756943 Codonopsis Species 0.000 claims description 10
- 210000000582 Semen Anatomy 0.000 claims description 10
- 239000010440 gypsum Substances 0.000 claims description 10
- 229910052602 gypsum Inorganic materials 0.000 claims description 10
- 239000008517 radix Trichosanthis Substances 0.000 claims description 10
- 235000001892 vitamin D2 Nutrition 0.000 claims description 10
- 239000009636 Huang Qi Substances 0.000 claims description 8
- 238000005520 cutting process Methods 0.000 claims description 8
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 160.7,153.3 L 144.3,136.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-0 atom-19' d='M 160.7,153.3 L 183.3,147.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-0 atom-19' d='M 162.9,147.9 L 178.7,143.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-8 atom-0' d='M 154.5,175.8 L 160.7,153.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 144.3,136.7 L 145.7,113.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-5 atom-1' d='M 121.8,142.6 L 144.3,136.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-1 atom-29' d='M 149.3,135.7 L 148.8,134.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-1 atom-29' d='M 154.3,134.6 L 153.2,131.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-1 atom-29' d='M 159.2,133.6 L 157.6,129.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 145.7,113.4 L 124.0,104.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-3' d='M 109.2,122.9 L 125.8,106.4 L 122.2,103.4 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-4 atom-4 atom-5' d='M 109.2,122.9 L 121.8,142.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-4 atom-10' d='M 109.2,122.9 L 85.9,121.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 121.8,142.6 L 115.5,165.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-5 atom-9' d='M 121.8,142.6 L 98.3,143.7 L 99.0,148.3 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-6 atom-6 atom-7' d='M 115.5,165.0 L 131.9,181.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 131.9,181.7 L 154.5,175.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 85.9,121.5 L 77.6,99.6 L 73.4,101.7 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-11 atom-10 atom-12' d='M 85.9,121.5 L 73.1,141.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 73.1,141.0 L 49.8,139.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 69.8,136.1 L 53.5,135.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 49.8,139.6 L 36.9,159.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 36.9,159.0 L 13.8,155.3 L 13.5,160.0 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-15 atom-14 atom-16' d='M 36.9,159.0 L 47.4,179.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 47.4,179.9 L 34.5,199.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-16 atom-18' d='M 47.4,179.9 L 70.6,181.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 183.3,147.4 L 199.6,164.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 199.6,164.1 L 222.2,158.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 201.9,158.7 L 217.7,154.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 222.2,158.2 L 238.6,174.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-29 atom-27 atom-21' d='M 228.4,135.7 L 222.2,158.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-22 atom-23' d='M 238.6,174.8 L 261.2,169.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-23 atom-24' d='M 263.9,172.8 L 265.0,171.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-23 atom-24' d='M 266.6,176.7 L 268.8,174.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-23 atom-24' d='M 269.3,180.5 L 272.6,177.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-23 atom-25' d='M 261.2,169.0 L 267.4,146.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-25 atom-26' d='M 267.4,146.5 L 251.0,129.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-26 atom-27' d='M 251.0,129.9 L 228.4,135.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-27 atom-28' d='M 230.1,134.1 L 213.7,117.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-27 atom-28' d='M 226.8,137.4 L 210.4,120.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='274.7' y='190.2' class='atom-24' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='281.2' y='190.2' class='atom-24' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='163.4' y='133.2' class='atom-29' style='font-size:9px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 43.6,42.9 L 39.1,38.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-0 atom-19' d='M 43.6,42.9 L 49.7,41.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-0 atom-19' d='M 44.2,41.4 L 48.5,40.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-8 atom-0' d='M 41.9,49.1 L 43.6,42.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 39.1,38.4 L 39.5,32.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-5 atom-1' d='M 32.9,40.0 L 39.1,38.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-1 atom-29' d='M 40.5,38.1 L 40.3,37.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-1 atom-29' d='M 41.9,37.8 L 41.6,37.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-1 atom-29' d='M 43.3,37.5 L 42.9,36.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 39.5,32.0 L 33.5,29.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-4 atom-3' d='M 29.5,34.6 L 34.0,30.1 L 33.0,29.3 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-4 atom-4 atom-5' d='M 29.5,34.6 L 32.9,40.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-4 atom-10' d='M 29.5,34.6 L 23.1,34.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 32.9,40.0 L 31.2,46.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-5 atom-9' d='M 32.9,40.0 L 26.5,40.3 L 26.7,41.5 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-6 atom-6 atom-7' d='M 31.2,46.1 L 35.7,50.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 35.7,50.7 L 41.9,49.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 23.1,34.2 L 20.8,28.2 L 19.7,28.8 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-11 atom-10 atom-12' d='M 23.1,34.2 L 19.6,39.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 19.6,39.5 L 13.2,39.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 18.7,38.2 L 14.3,37.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 13.2,39.1 L 9.7,44.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-14 atom-15' d='M 9.7,44.5 L 3.4,43.5 L 3.3,44.7 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-15 atom-14 atom-16' d='M 9.7,44.5 L 12.6,50.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 12.6,50.2 L 9.1,55.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-16 atom-18' d='M 12.6,50.2 L 18.9,50.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 49.7,41.3 L 54.2,45.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 54.2,45.8 L 60.4,44.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 54.8,44.4 L 59.1,43.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 60.4,44.2 L 64.8,48.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-29 atom-27 atom-21' d='M 62.1,38.1 L 60.4,44.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-22 atom-23' d='M 64.8,48.8 L 71.0,47.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-23 atom-24' d='M 71.7,48.2 L 72.0,47.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-23 atom-24' d='M 72.4,49.2 L 73.0,48.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-23 atom-24' d='M 73.1,50.2 L 74.0,49.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-23 atom-25' d='M 71.0,47.2 L 72.7,41.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-25 atom-26' d='M 72.7,41.0 L 68.2,36.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-26 atom-27' d='M 68.2,36.5 L 62.1,38.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-27 atom-28' d='M 62.5,37.6 L 58.1,33.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-27 atom-28' d='M 61.6,38.5 L 57.1,34.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='73.7' y='54.7' class='atom-24' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='77.8' y='54.7' class='atom-24' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='43.3' y='39.1' class='atom-29' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims description 8
- 239000011653 vitamin D2 Substances 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 6
- 235000013305 food Nutrition 0.000 claims description 5
- 241000245240 Lonicera Species 0.000 claims description 4
- 235000013399 edible fruits Nutrition 0.000 claims description 4
- 210000003165 Abomasum Anatomy 0.000 claims description 2
- 241000605447 Anemarrhena Species 0.000 claims description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 2
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 2
- 240000003917 Bambusa tulda Species 0.000 claims description 2
- 241000212941 Glehnia Species 0.000 claims description 2
- 235000014676 Phragmites communis Nutrition 0.000 claims description 2
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 2
- 241000545442 Radix Species 0.000 claims description 2
- 241001530126 Scrophularia Species 0.000 claims description 2
- 239000011425 bamboo Substances 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- -1 remove stem and leaf Substances 0.000 claims description 2
- 238000009738 saturating Methods 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 230000001429 stepping Effects 0.000 claims description 2
- 239000004575 stone Substances 0.000 claims description 2
- 210000004185 Liver Anatomy 0.000 abstract description 13
- 230000000694 effects Effects 0.000 abstract description 7
- 231100000331 toxic Toxicity 0.000 abstract description 5
- 231100000486 side effect Toxicity 0.000 abstract description 3
- 230000001988 toxicity Effects 0.000 abstract description 3
- 231100000419 toxicity Toxicity 0.000 abstract description 3
- 230000002936 tranquilizing Effects 0.000 abstract description 2
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241001573366 Astragalus membranaceus Species 0.000 abstract 1
- 240000000218 Cannabis sativa Species 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 241000037740 Coptis chinensis Species 0.000 abstract 1
- 240000007171 Imperata cylindrica Species 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 241000756042 Polygonatum Species 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000008422 Schisandra chinensis Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 description 29
- 235000019634 flavors Nutrition 0.000 description 29
- 210000000952 Spleen Anatomy 0.000 description 22
- 210000003734 Kidney Anatomy 0.000 description 20
- 210000004369 Blood Anatomy 0.000 description 19
- 239000008280 blood Substances 0.000 description 19
- 210000002784 Stomach Anatomy 0.000 description 18
- 235000009508 confectionery Nutrition 0.000 description 14
- 206010037660 Pyrexia Diseases 0.000 description 12
- 230000001717 pathogenic Effects 0.000 description 11
- 206010012735 Diarrhoea Diseases 0.000 description 10
- 206010007247 Carbuncle Diseases 0.000 description 9
- 231100000614 Poison Toxicity 0.000 description 9
- 230000035922 thirst Effects 0.000 description 9
- 206010030113 Oedema Diseases 0.000 description 8
- 208000002193 Pain Diseases 0.000 description 8
- 230000036407 pain Effects 0.000 description 8
- 230000027939 micturition Effects 0.000 description 7
- 206010042674 Swelling Diseases 0.000 description 6
- 201000008286 diarrhea Diseases 0.000 description 6
- 201000010099 disease Diseases 0.000 description 6
- 230000001737 promoting Effects 0.000 description 6
- 230000002269 spontaneous Effects 0.000 description 6
- 230000002522 swelling Effects 0.000 description 6
- 239000003440 toxic substance Substances 0.000 description 6
- 206010003549 Asthenia Diseases 0.000 description 5
- 206010010774 Constipation Diseases 0.000 description 5
- 208000001848 Dysentery Diseases 0.000 description 5
- 208000001780 Epistaxis Diseases 0.000 description 5
- 206010043458 Thirst Diseases 0.000 description 5
- 206010068760 Ulcers Diseases 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 5
- 231100000397 ulcer Toxicity 0.000 description 5
- 200000000019 wound Diseases 0.000 description 5
- 206010000087 Abdominal pain upper Diseases 0.000 description 4
- 210000001124 Body Fluids Anatomy 0.000 description 4
- 206010013781 Dry mouth Diseases 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 4
- 206010013975 Dyspnoeas Diseases 0.000 description 4
- 206010013990 Dysuria Diseases 0.000 description 4
- 210000001624 Hip Anatomy 0.000 description 4
- 206010023126 Jaundice Diseases 0.000 description 4
- 210000003205 Muscles Anatomy 0.000 description 4
- 210000003800 Pharynx Anatomy 0.000 description 4
- 208000001431 Psychomotor Agitation Diseases 0.000 description 4
- 206010038743 Restlessness Diseases 0.000 description 4
- 239000010839 body fluid Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000003014 reinforcing Effects 0.000 description 4
- 210000001015 Abdomen Anatomy 0.000 description 3
- 210000000988 Bone and Bones Anatomy 0.000 description 3
- 208000002173 Dizziness Diseases 0.000 description 3
- 206010016256 Fatigue Diseases 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 210000003026 Hypopharynx Anatomy 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 210000002105 Tongue Anatomy 0.000 description 3
- 210000002700 Urine Anatomy 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 235000019789 appetite Nutrition 0.000 description 3
- 230000036528 appetite Effects 0.000 description 3
- 235000019658 bitter taste Nutrition 0.000 description 3
- 230000001684 chronic Effects 0.000 description 3
- 230000002950 deficient Effects 0.000 description 3
- 230000003203 everyday Effects 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 210000000629 knee joint Anatomy 0.000 description 3
- 244000052769 pathogens Species 0.000 description 3
- 239000002574 poison Substances 0.000 description 3
- 238000010791 quenching Methods 0.000 description 3
- 230000000306 recurrent Effects 0.000 description 3
- 230000035900 sweating Effects 0.000 description 3
- 230000002588 toxic Effects 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 206010002156 Anal fistula Diseases 0.000 description 2
- 208000002399 Aphthous Stomatitis Diseases 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 206010012218 Delirium Diseases 0.000 description 2
- 206010013954 Dysphoria Diseases 0.000 description 2
- 206010016286 Febrile disease Diseases 0.000 description 2
- 210000003128 Head Anatomy 0.000 description 2
- 208000000616 Hemoptysis Diseases 0.000 description 2
- 206010022114 Injury Diseases 0.000 description 2
- 208000009856 Lung Disease Diseases 0.000 description 2
- 206010029410 Night sweats Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000008128 Pulmonary Tuberculosis Diseases 0.000 description 2
- 208000009205 Tinnitus Diseases 0.000 description 2
- 208000005946 Xerostomia Diseases 0.000 description 2
- 201000000736 amenorrhea Diseases 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 230000003419 expectorant Effects 0.000 description 2
- 239000003172 expectorant agent Substances 0.000 description 2
- 235000019525 fullness Nutrition 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 201000007227 lymph node tuberculosis Diseases 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 230000025627 positive regulation of urine volume Effects 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 230000001047 pyretic Effects 0.000 description 2
- 230000035812 respiration Effects 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 235000014347 soups Nutrition 0.000 description 2
- 230000001225 therapeutic Effects 0.000 description 2
- 231100000886 tinnitus Toxicity 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 208000006673 Asthma Diseases 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 208000002894 Beriberi Diseases 0.000 description 1
- 210000000481 Breast Anatomy 0.000 description 1
- 206010006895 Cachexia Diseases 0.000 description 1
- 206010008479 Chest pain Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010061428 Decreased appetite Diseases 0.000 description 1
- 241000668709 Dipterocarpus costatus Species 0.000 description 1
- 208000005679 Eczema Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 206010015958 Eye pain Diseases 0.000 description 1
- 206010016029 Face oedema Diseases 0.000 description 1
- 206010016326 Feeling cold Diseases 0.000 description 1
- 210000003754 Fetus Anatomy 0.000 description 1
- 206010016766 Flatulence Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 240000004859 Gamochaeta purpurea Species 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 206010067715 Gastrointestinal sounds abnormal Diseases 0.000 description 1
- 208000001786 Gonorrhea Diseases 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 206010018830 Haematemesis Diseases 0.000 description 1
- 206010018836 Haematochezia Diseases 0.000 description 1
- 206010018987 Haemorrhage Diseases 0.000 description 1
- 206010019233 Headache Diseases 0.000 description 1
- 206010019345 Heat stroke Diseases 0.000 description 1
- 208000002287 Hemorrhoids Diseases 0.000 description 1
- 208000005252 Hepatitis A Diseases 0.000 description 1
- 206010019780 Hepatitis infectious Diseases 0.000 description 1
- 206010020039 Hiccups Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 210000003127 Knee Anatomy 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 210000000214 Mouth Anatomy 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 206010037211 Psychomotor hyperactivity Diseases 0.000 description 1
- 210000004915 Pus Anatomy 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 210000003296 Saliva Anatomy 0.000 description 1
- 210000003491 Skin Anatomy 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- 210000003802 Sputum Anatomy 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 208000009189 Tinea Favosa Diseases 0.000 description 1
- 206010043866 Tinea capitis Diseases 0.000 description 1
- 208000004371 Toothache Diseases 0.000 description 1
- 231100000765 Toxin Toxicity 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 208000001877 Whooping Cough Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000001154 acute Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000001166 anti-perspirant Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 231100000319 bleeding Toxicity 0.000 description 1
- 230000000740 bleeding Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000002612 cardiopulmonary Effects 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 201000004624 dermatitis Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 231100001003 eczema Toxicity 0.000 description 1
- 230000029578 entry into host Effects 0.000 description 1
- 201000000297 erysipelas Diseases 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002496 gastric Effects 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 229920000591 gum Polymers 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000001976 improved Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000002175 menstrual Effects 0.000 description 1
- 101710031899 moon Proteins 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 244000045947 parasites Species 0.000 description 1
- 201000005702 pertussis Diseases 0.000 description 1
- 201000002367 primary immunodeficiency disease Diseases 0.000 description 1
- 230000000171 quenching Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 230000007958 sleep Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000002087 whitening Effects 0.000 description 1
Abstract
本发明公开了一种治疗肺热咳嗽的药物及其制备方法，它主要是由党参、黄芪、知母、黄连、五味子、玄参、白茅根、桑白皮、忍冬藤、玉竹、黄精等药物按一定重量配比制备而成，本发明药物具有养心安神，疏肝解郁，清热解毒的功能，用于治疗肺热咳嗽见效快，疗效好，无毒副作用。
Description
一种治疗肺热咳嗽的药物及其制备方法
技术领域
[0001] 本发明涉及一种用于治疗肺热咳嗽的药物及其制备方法，属中药领域。
背景技术
[0002] 肺热咳嗽是由于风热邪毒犯肺，或风寒化热，邪热蕴肺，肺受热毒所灼，痰热内部导致肺内郁热出现以咳嗽为主的典型症状，常在肺热感冒症状后出现。肺热咳嗽常多见于免疫力低下的中老年体弱者，主要表现为反复咳嗽。目前，西药治疗肺热咳嗽效果不佳，且长期服用西药有较多副作用，因此，人们对有效治疗肺热咳嗽的中药存在很大的需求。
发明内容
[0003] 本发明人依据中医理论的研究及临床反复的试验和验证，终于找到了有效治疗肺热咳嗽的药物，从而完成了本发明。
[0004] 本发明的目的就是提供一种能够有效治疗肺热咳嗽的组合药物。
[0005] 本发明的另一个目的就是提供了该组合药物的制备方法。
[0006] 本发明药物是选用党参、黄芪、知母、黄连、五味子、玄参、白茅根、桑白皮、忍冬藤、玉竹、黄精、北沙参、麦冬、金银花、寒水石、山茱萸、大黄、益智仁、甘草、白术、荜澄茄、金樱子、泽兰、菟丝子、生 地黄、红花、女贞子、天花粉、石膏、山药药物进行组合的，将这些药物组合使得各药物功效产生协同作用，从而能够快速治疗肺热咳嗽的复发。其中选用党参是因为其性味甘，平，入手、足太阴经气分，有补中益气，生津的功能，治脾胃虚弱，气血两亏，体倦无力，食少，口渴，久泻，脱肛。选用黄芪是因为其性味甘，微温，入肺、脾经，生用有益卫固表，利水消肿，托毒，生肌的功能，治自汗，盗汗，血痹，浮肿，痈疽不溃或溃久敛；炙用有补中益的功能，治内伤劳倦，脾虚泄泻，脱肛，气虚血脱，崩带及一切气衰血虚之症。选用知母是因为其性味苦，寒，入肺、胃、肾经，有滋阴降火，润燥滑肠的功能，治烦热消渴，骨蒸劳热，肺热咳嗽，大便燥结，小便不利。选用黄连是因为其性味苦，寒，入心、肝、胃、大肠经，有泻火，燥湿，解毒，杀虫的功能，治时行热毒、伤寒，热盛心烦，痞满呕逆，菌痢，热泻腹痛，肺结核，吐、衄、下血，消渴，疳积，蛔虫病，百日咳，咽喉肿痛，火眼，口疮，痈疽疮毒，湿疫，汤火烫伤。选用五味子是因为其性味酸，温，入肺、肾经，有敛肺，滋肾，生津，收汗，涩精的功能，治肺虚喘咳，口干作渴，自汗，盗汗，劳伤羸瘦，梦遗滑精，久泻久痢。选用玄参是因为其性味苦咸，凉，入肺、肾经，有滋阴，降火，除烦，解毒的功能，治热病烦渴，发斑，骨蒸劳热，夜寐不宁，自汗盗汗，津伤便秘，吐血衄血，咽喉肿痛，痈肿，瘰疬。选用白茅根是因为其性味甘、寒，入肺、胃、小肠经，有凉血，止血，清热，利尿的功能，治热病烦渴，吐血，衄血，肺热喘急，胃热哕逆，淋病，小便不利，水肿，黄疸。选用桑白皮是因为其性味甘，寒，入肺、脾经，有泻肺平喘，行水消肿的功能，治肺热喘咳，吐血，水肿，脚气，小便不利。选用忍冬藤是因为其性味甘，寒，入心、肺经，有清热，解毒，通络的功能，治温病发热，热毒血痢，传染性肝炎，痈肿疮毒，筋骨疼痛。选用玉竹是因为其性味甘，平，入肺，胃经，有养阴，润燥，除烦，止渴的功能，治热病阳伤，咳嗽，烦渴，虚劳发热，消谷易饥，小便频数。选用黄精是因为其性味甘平，入脾、肺、肾经，有补中益气，润心肺，强筋骨的功能，治虚损寒热，肺痨咳血，病后体虚食少，筋骨软弱，风湿疼痛，风癞癣疾。选用北沙参是因为其性味甘苦淡，凉，入肺、脾经，有养阴清肺，祛痰止咳的功能，治肺热燥咳，虚痨久咳，阴伤咽干、口渴。选用麦冬是因为其性味甘微苦，寒，入肺、胃、心经，有养阴润肺，清心除烦，益胃生津的功能，治肺燥干咳，吐血，咯血，肺痿，肺痈，虚劳烦热，清渴，热病津伤，咽干口燥，便秘。选用金银花是因为其性味甘，寒，入肺、胃经，有清热，解毒的功能，治温病发热，热毒血痢，痈疡，肿毒，瘰疬，痔漏。选用寒水石是因为其性味辛咸，寒，入心、胃、肾经，有清热降火，利窍，消肿的功能，治时行热病，积热烦渴，吐泻，水肿，尿闭，齿衄，丹毒，烫伤。选用山茱萸是因为其性味酸，微温，入肝、肾经，有补肝肾，涩精气，固虚脱的功能，治腰膝酸痛，眩晕，耳鸣，阳痿，遗精，小便频数，肝虚寒热，虚汗不止，心摇脉散。选用大黄是因为其性味苦、寒，入胃、大肠、肝径，有泻热毒，破积滞，行瘀血的功能，治实热便秘，谵语发狂，食积痞满，痢疾初起，里急后重，瘀停经闭，癥瘕积聚，时行热疫，暴眼赤痛，吐血，衄血，阳黄，水肿，淋浊，溲赤，痈疡肿毒，疔疮，汤火伤。选用益智仁是因为其性味辛，温，入脾、肾经，有温脾，暖肾，固气，涩精的功能，治冷气腹痛，中寒吐泻，多唾，遗精，小便余浙，夜多小便。选用甘草是因为其性味甘平，入脾、胃、肺经，有和中缓急，润肺，解毒，调和诸药的功能，炙用治脾胃虚弱，食少，腹痛便溏，劳倦发热，肺痿咳嗽，心悸，惊痈，生用治咽喉肿痛，消 化性溃疡，痈疽疮疡，解药毒及食物中毒。选用白术是因为其性味苦甘，温，入脾、胃经，有补脾，益胃，燥湿，和中的功能，治脾胃气弱，不思饮食，倦怠少气，虚胀，泄泻，痰饮，水肿，黄疸，湿痹，小便不利，头晕，自汗，胎气不安。选用荜澄茄是因为其性味辛，温，入脾、肾经，有温暖脾肾，健胃消食的功能，治食积气胀，脘腹冷痛，反胃呕吐，肠鸣泄泻，痢疾，痰癖。选用金樱子是因为其性味酸涩，平，有固精涩肠，缩尿止泻的功能，治滑精，遗尿，小便频数，脾虚泻痢。选用泽兰是因为其性味苦辛，微温，入肝、脾经，有活血，行水的功能，治经闭，癥瘕，产后瘀滞腹痛，身面浮肿，跌扑损伤，金疮，痈肿。选用菟丝子是因为其性味辛甘，平，入肝、肾经，有补肝肾，益精髓，明目的功能，治腰膝酸痛，遗精，消渴，尿有余浙，目暗。选用生地黄是因为其性味甘，寒，归心、肝、肾经，有清热凉血，养阴，生津的功能，治热病烦渴，阴虚内热，骨蒸劳热，内热消渴，吐血，衄血，发斑发疹。选用红花是因为其性味辛，温，入心、肝经，有活血通经，去瘀止痛的功能，治经闭，癥瘕，难产，死胎，产后恶露不行，瘀血作痛，痈肿，跌扑损伤。选用女贞子是因为其性味苦甘，平，入肝、肾经，有补肝肾，强腰膝的功能，治阴虚内热，头晕，目花耳鸣，腰膝酸软，须发早白。选用天花粉是因为其性味甘苦酸，凉，入肺、胃经，有生津，止渴，降火，润燥，排脓，消肿的功能，治热病口渴，消渴，黄疸，肺燥咳血，痈肿，痔瘘。选用石膏是因为其性味辛甘，寒，入肺、胃经，生用有解肌清热，除烦止渴的功能，治热病壮热不退，心烦神昏，谵语发狂，口渴咽干，肺热喘急，中暑自汗，胃火头痛、牙痛，热毒壅盛，发斑发疹，口舌生疮，煅敷生肌敛疮，外治痈疽疮疡，溃不收回，汤火烫伤。选用山药是因为其性味甘，平，入肺、脾、肾经，有健脾，补肺，固肾，益精的功能，治脾虚泄泻，久痢，虚劳咳嗽，消渴，遗精、带下，小便频数。
具体实施方式
[0007] 本发明组分的药物用量也是发明人经过大量摸索总结得出的，各组分的用量在下述重量范围内都具有较好疗效
党参 5-15克 黄芪 10-20克知母 10-20克黄连 5-15克 五味子 10-20克玄参 10-20克
白茅根 15-25克 桑白皮 15-25克忍冬藤 15-25克
玉竹 15-25克 黄精 15-25克北沙参 15-25克
麦冬 15-25克 金银花 15-25克寒水石 15-25克
山茱萸 5-15克 大黄 10-20克益智仁 10-20克
甘草 5-15克 白术 10-20克荜澄茄 10-20克
金樱子 5-15克 泽兰 10-20克菟丝子 10-20克
生地黄 5-15克 红花 10-20克女贞子 10-20克
天花粉 5-15克 石膏 15-25克山药 10-20克
优选用量为
党参 10克 黄芪 15克 知母 15克
黄连 10克 五味子 15克 玄参 15克
白茅根 20克 桑白皮 20克 忍冬藤 20克
玉竹 20克 黄精 20克 北沙参 20克
麦冬 20克 金银花 20克 寒水石 20克
山茱萸 10克 大黄 15克 益智仁 15克
甘草 10克 白术 15克 荜澄茄 15克
金樱子 10克 泽兰 15克 菟丝子 15克
生地黄 10克 红花 15克 女贞子 15克
天花粉 10克 石膏 20克 山药 15克
本发明药物的制备方法如下 一、备料
1、党参:洗净泥沙后润透去芦，切片或切段，晒干；
2、黄芪:拣净杂质，除去残留的根头和空心较大者，用水浸泡，捞出，润透后及时切片，晒干；
3、知母:拣净杂质，用水撞洗，捞出，润软，切片晒干；
4、黄连:拣去杂质，洗净泥砂，润透，切片，阴干；
5、五味子:筛去灰屑，除去杂质，置蒸笼内蒸透，取出晒干；
6、玄参:拣净杂质，除去芦头，洗净润透，切片，晾干；
7、白茅根:拣净杂质，洗净，微润，切段，晒干，簸净碎屑；
8、桑白皮:刷去灰屑，洗净，润透后切丝，晒干；
9、忍冬藤:拣去杂质，用水浸泡，润透，切片，晒干；
10、玉竹:除去杂质，洗净泥土，闷润至内外湿度均匀，切片，晒干；
11、黄精:洗净泥土，略润，切片，晒干；
12、北沙参:拣去杂质，除去茎基，用水略洗，捞出，稍润，切段，晒干；
13、麦冬:拣净杂质，用水浸泡，捞出，润透后抽去心，再洗净晒干；
14、金银花:筛去泥沙，拣净杂质；
15、寒水石:取原药材，除去杂质，洗净，干燥，打成碎块；
16、山茱萸:洗净，除去果核及杂质，晒干；17、大黄:拣净杂质，大小分档，焖润至内外湿度均匀，切片或切成小块、晒干；
18、益智仁:取益智仁置锅内，炒至外壳焦黑，取出冷透，除去果壳，取仁捣碎用；
19、甘草:拣去杂质，洗净，用水浸泡至八成透时，捞出，润透，切片，凉干；
20、白术:拣净杂质,用水浸泡,泡后捞出，润透,切片，晒干；
21、荜澄茄:拣去杂质，摘去果柄，洗净，晒干；
22、金樱子:拣去杂质，切两瓣，用水稍浸泡，捞出，闷润后除去残留毛刺，挖净毛、核，干
燥；
23、泽兰:拣去杂质，除去残根，喷水稍润，切段晒干；
24、菟丝子:过萝去净杂质，洗净，晒干；
25、生地黄:取原药材，除去杂质，洗净，稍润，切厚片，干燥，筛去碎屑；
26、红花:拣净杂质，除去茎叶、蒂头，晒干；
27、女贞子:拣去杂质，洗净，晒干；
28、天花粉:拣去杂质，大小块分开，用水泡至六成透，捞出，闷润至内外湿度均匀，切片，晒干，或用水洗净，捞出，晒干，捣成小块；
29、石膏:去净杂石，洗净泥土，打碎成小块；
30、山药:拣净杂质，用水浸泡至山药中心部软化时，捞出稍晾，切片晒干或烘干。
[0008] 二、制备
1、将所述重量的党参、黄芪、知母、黄连、五味子、玄参、白茅根、桑白皮、忍冬藤、玉竹、黄精、北沙参、麦冬、金银花、寒水石、山茱萸、大黄、益智仁、甘草、白术、荜澄茄、金樱子、泽兰、菟丝子、生地黄、红花、女贞子、天花粉、石膏、山药药物加水煎煮二次，第一次加水8倍量，浸泡180分钟后，武火煎煮沸腾10分钟，再用文火煎煮30分钟，过滤得第一次煎煮液。
[0009] 2、将过滤的药渣加水6倍量，武火煮沸，再用文火煎煮20分钟，过滤得第二次煎煮液。
[0010] 3、合并两次煎煮液，分成4剂服用。
[0011] 本发明药物具有养心安神，疏肝解郁，清热解毒的功能，用于治疗肺热咳嗽，疗程短、见效快、无毒副作用。
[0012] 以下通过试验例来进一步阐述本发明所述药物的有益效果，这些试验例包括了本发明药物的动物毒性试验报告和临床观察资料。
[0013][试验例I]本发明药物的动物毒性试验报告
取家兔30只，雌雄兼用，体重2.0-2.3kg，分两组，每组15只，其中一组为超剂量试验组，另一组为正常量试验组。超常量组为20ml/kg，正常量为10ml/kg，给药方式为灌胃法给药，每天2次，连服7天，每天观察给药反应，结果表明二组家兔活动、饮食正常，药物无不良毒副作用。
[0014][试验例2]本发明药物治疗肺热咳嗽的观察资料
1、一般资料
收治肺热咳嗽患者共217例。
[0015] 2、诊断标准
肺热咳嗽主 要症状之一为反复咳嗽，常伴有恶寒发热，咳嗽胸痛，痰少而粘，呼吸不利、口干咽燥，舌苔薄黄，脉浮滑而数。部分还伴有胸胁隐痛、气短乏力、自汗盗汗，低热或潮热，面色少华，形体消瘦等症状。
[0016] 临床主要表现为反复咳嗽，咳黄痰，伴有口干，咽痛，便秘，尿赤，身热或伴有喘息等症状，舌质红，苔薄黄或黄腻，少津，脉滑数或细数。
[0017] 3、治疗方法
选用上述药剂，给患者服用，每次服用I剂，每天早、晚各服I次，7天为一个疗程，连续服用3个疗程。
[0018] 4、疗效评定标准
显效:肺热咳嗽症状消失，观察半年无反弹者；
好转:肺热咳嗽症状明显改善，体质逐步增强；
无效:肺热咳嗽症状无改变，达不到好转标准者。
[0019] 5、治疗结果(见下表)
在上述的治疗中，用本发明药物治疗肺热咳嗽患者217例，结果显效206例，显效率为94.93%，好转8例，好转率为3.69%，无效3例，总有效率为98.62%。
Claims (3)
1.一种治疗肺热咳嗽的药物，其特征在于:它是由下列重量范围内的原料药制成: 党参5-15克黄芪10-20克知母10-20克 黄连5-15克五味子10-20克玄参10-20克 白茅根15-25克桑白皮15-25克忍冬藤15-25克 玉竹15-25克黄精15-25克北沙参15-25克 麦冬15-25克金银花15-25克寒水石15-25克 山茱萸 5-15克大黄10-20克益智仁10-20克 甘草5-15克白术10-20克荜澄茄10-20克 金樱子5-15克泽兰10-20克菟丝子10-20克 生地黄5-15克红花10-20克女贞子10-20克 天花粉5-15克石膏15-25克山药10-20克。
2.根据权利要求1所述的药物，其中各原料药的用量为: 党参10克黄芪15克知母15克 黄连10克五味子15克玄参15克 白茅根20克桑白皮20克忍冬藤20克 玉竹20克黄精20克北沙参20克 麦冬20克金银花20克寒水石20克 山茱萸 10克大黄15克益智仁15克 甘草10克白术15克荜澄茄15克 金樱子10克泽兰15克菟丝子15克 生地黄10克红花15克女贞子15克 天花粉10克石膏20克山药15克。
3.根据权利要求1或2所述药物的制备方法，它包括下列步骤: (一)备料 (1)党参:洗净泥沙后润透去芦，切片或切段，晒干； (2)黄芪:拣净杂质，除去残留的根头和空心较大者，用水浸泡，捞出，润透后及时切片，晒干； (3)知母:拣净杂质，用水撞洗，捞出，润软，切片晒干； (4)黄连:拣去杂质，洗净泥砂，润透，切片，阴干； (5)五味子:筛去灰屑，除去杂质，置蒸笼内蒸透，取出晒干； (6)玄参:拣净杂质，除去芦头，洗净润透，切片，晾干； (7)白茅根:拣净杂质，洗净，微润，切段，晒干，簸净碎屑； (8)桑白皮:刷去灰屑，洗净，润透后切丝，晒干； (9)忍冬藤:拣去杂质，用水浸泡，润透，切片，晒干； (10)玉竹:除去杂质，洗净泥土，闷润至内外湿度均匀，切片，晒干； (11)黄精:洗净泥土，略润，切片，晒干； (12)北沙参:拣去杂质，除去茎基，用水略洗，捞出，稍润，切段，晒干； (13)麦冬:拣净杂质，用水浸泡，捞出，润透后抽去心，再洗净晒干； (14)金银花:筛去泥沙，拣净杂质；(15)寒水石:取原药材，除去杂质，洗净，干燥，打成碎块； (16)山茱萸:洗净，除去果核及杂质，晒干； (17)大黄:拣净杂质，大小分档，焖润至内外湿度均匀，切片或切成小块、晒干； (18)益智仁:取益智仁置锅内，炒至外壳焦黑，取出冷透，除去果壳，取仁捣碎用； (19)甘草:拣去杂质，洗净，用水浸泡至八成透时，捞出，润透，切片，凉干； (20)白术:拣净杂质,用水浸泡,泡后捞出，润透,切片，晒干； (21)荜澄茄:拣去杂质，摘去果柄，洗净，晒干； (22)金樱子:拣去杂质，切两瓣，用水稍浸泡，捞出，闷润后除去残留毛刺，挖净毛、核，干燥； (23)泽兰:拣去杂质，除去残根，喷水稍润，切段晒干； (24)菟丝子:过萝去净杂质，洗净，晒干； (25)生地黄:取原药材，除去杂质，洗净，稍润，切厚片，干燥，筛去碎屑； (26)红花:拣净杂质，除去茎叶、蒂头，晒干； (27)女贞子 :拣去杂质，洗净，晒干； (28)天花粉:拣去杂质，大小块分开，用水泡至六成透，捞出，闷润至内外湿度均匀，切片，晒干，或用水洗净，捞出，晒干，捣成小块； (29)石膏:去净杂石，洗净泥土，打碎成小块； (30)山药:拣净杂质，用水浸泡至山药中心部软化时，捞出稍晾，切片晒干或烘干； (二)制备 (1)将所述重量的党参、黄芪、知母、黄连、五味子、玄参、白茅根、桑白皮、忍冬藤、玉竹、黄精、北沙参、麦冬、金银花、寒水石、山茱萸、大黄、益智仁、甘草、白术、荜澄茄、金樱子、泽兰、菟丝子、生地黄、红花、女贞子、天花粉、石膏、山药药物加水煎煮二次，第一次加水8倍量，浸泡180分钟后，武火煎煮沸腾10分钟，再用文火煎煮30分钟，过滤得第一次煎煮液； (2)将过滤的药渣加水6倍量，武火煮沸，再用文火煎煮20分钟，过滤得第二次煎煮液； (3)合并两次煎煮液，分成4剂服用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410038493.8A CN103751682B (zh) | 2014-01-27 | 2014-01-27 | 一种治疗肺热咳嗽的药物及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410038493.8A CN103751682B (zh) | 2014-01-27 | 2014-01-27 | 一种治疗肺热咳嗽的药物及其制备方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103751682A true CN103751682A (zh) | 2014-04-30 |
| CN103751682B CN103751682B (zh) | 2016-03-30 |
Family
ID=50519109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410038493.8A Expired - Fee Related CN103751682B (zh) | 2014-01-27 | 2014-01-27 | 一种治疗肺热咳嗽的药物及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103751682B (zh) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961584A (zh) * | 2014-05-29 | 2014-08-06 | 刘士和 | 一种治疗肺热的药物及其制备方法 |
| CN104906378A (zh) * | 2015-06-21 | 2015-09-16 | 臧海阳 | 一种治疗肺热咳嗽的中药组合物 |
| CN105194406A (zh) * | 2015-10-28 | 2015-12-30 | 黄秋丽 | 一种肺热咳嗽药及其制备方法 |
| CN105560982A (zh) * | 2016-01-04 | 2016-05-11 | 成都富豪斯生物科技有限公司 | 一种治疗肺热咳嗽的内服药物及其制备方法 |
| CN105770398A (zh) * | 2016-04-11 | 2016-07-20 | 吴金霞 | 红景天止咳宁 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101062266A (zh) * | 2007-05-23 | 2007-10-31 | 陈江 | 泻火止咳散 |
-
2014
- 2014-01-27 CN CN201410038493.8A patent/CN103751682B/zh not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101062266A (zh) * | 2007-05-23 | 2007-10-31 | 陈江 | 泻火止咳散 |
Non-Patent Citations (1)
| Title |
|---|
| 吴玉涛: "咳嗽辨治雏议", 《云南中医中药杂志》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961584A (zh) * | 2014-05-29 | 2014-08-06 | 刘士和 | 一种治疗肺热的药物及其制备方法 |
| CN104906378A (zh) * | 2015-06-21 | 2015-09-16 | 臧海阳 | 一种治疗肺热咳嗽的中药组合物 |
| CN105194406A (zh) * | 2015-10-28 | 2015-12-30 | 黄秋丽 | 一种肺热咳嗽药及其制备方法 |
| CN105560982A (zh) * | 2016-01-04 | 2016-05-11 | 成都富豪斯生物科技有限公司 | 一种治疗肺热咳嗽的内服药物及其制备方法 |
| CN105770398A (zh) * | 2016-04-11 | 2016-07-20 | 吴金霞 | 红景天止咳宁 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103751682B (zh) | 2016-03-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103505630B (zh) | 一种治疗糖尿病的药物及其制备方法 | |
| CN103405658B (zh) | 一种治疗糖尿病的药物及其制备方法 | |
| CN103751682B (zh) | 一种治疗肺热咳嗽的药物及其制备方法 | |
| CN102973822B (zh) | 一种治疗口臭的药物及其制备方法 | |
| CN103736037A (zh) | 一种治疗慢性疲劳综合症的药物及其制备方法 | |
| CN103656406B (zh) | 一种治疗肺结核的药物及其制备方法 | |
| CN102805843A (zh) | 一种治疗胃痛的药物及其制备方法 | |
| CN103977306A (zh) | 一种治疗乙型肝炎的药物及其制备方法 | |
| CN102631655B (zh) | 一种治疗冠心病的药物及其制备方法 | |
| CN103751750B (zh) | 一种治疗口腔溃疡的药物及其制备方法 | |
| CN103961616A (zh) | 一种治疗过敏性咳嗽的药物及其制备方法 | |
| CN103550694A (zh) | 一种治疗脱发的药物及其制备方法 | |
| CN106110184A (zh) | 一种治疗脂肪肝的药物及其制备方法 | |
| CN105343678A (zh) | 一种治疗肺炎的药物及其制备方法 | |
| CN103263575B (zh) | 一种治疗头痛的药物及其制备方法 | |
| CN104435684A (zh) | 一种治疗口腔溃疡的药物及其制备方法 | |
| CN104398925A (zh) | 一种治疗皮肤病的药物及其制备方法 | |
| CN103961584A (zh) | 一种治疗肺热的药物及其制备方法 | |
| CN103751730A (zh) | 一种治疗单纯性肥胖症的药物及其制备方法 | |
| CN108524888A (zh) | 一种治疗失眠的药物及其制备方法 | |
| CN103566066B (zh) | 一种治疗脂溢性皮炎的药物及其制备方法 | |
| CN105213946A (zh) | 一种治疗便秘的药物及其制备方法 | |
| CN105456928A (zh) | 一种治疗类风湿性关节炎的药物及其制备方法 | |
| CN105412830A (zh) | 一种治疗急性黄疸型肝炎的药物及其制备方法 | |
| CN105327194A (zh) | 一种治疗贫血的药物及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| C06 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| C10 | Entry into substantive examination | ||
| GR01 | Patent grant | ||
| C14 | Grant of patent or utility model | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160330 Termination date: 20200127 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |