CN108524888A - 一种治疗失眠的药物及其制备方法 - Google Patents

一种治疗失眠的药物及其制备方法 Download PDF

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CN108524888A
CN108524888A CN201810526026.8A CN201810526026A CN108524888A CN 108524888 A CN108524888 A CN 108524888A CN 201810526026 A CN201810526026 A CN 201810526026A CN 108524888 A CN108524888 A CN 108524888A
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张永红
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张永红
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Abstract

本发明公开了一种治疗失眠的药物及其制备方法,其是由酸枣仁、党参、茯神、大枣、百合、琥珀、甘草、珍珠母、山楂、鹿茸、菟丝子、远志、合欢皮、莱菔子、半夏、连翘、杜仲、木香、干姜、乳香、黄芪、白术、黄连、陈皮、石菖蒲、人参、生地黄、牛膝、当归、肉桂、鸡血藤、何首乌、龙骨、桔梗、墨旱莲、仙鹤草重量配比制备而成,本发明药物具有养肝、宁心安神、补中益气、补脾和胃、平肝潜阳、养阴生津的功能,用于治疗失眠见效快、疗效好,不复发。

Description

一种治疗失眠的药物及其制备方法
技术领域
[0001] 本发明涉及一种治疗失眠的药物及其制备方法,属中药领域。 技术背景
[0002] 失眠是指无法入睡或无法保持睡眠状态,导致睡眠不足。又称入睡和维持睡眠障 碍①IMS),为各种原因引起入睡困难、睡眠深度或频度过短、早醒及睡眠时间不足或质量 差。中医则认为失眠与肝郁化火、心脾两虚、阴虚火旺、心虚畏怯有关。由于西药治疗副作用 大,因此人们对有效治疗失眠的中药药物存在极大的需求,至今为止,还没有发现关于本发 明的有关报道。
发明内容
[0003] 本发明人依据中医理论的研究和临床试验的反复验证,终于找到了有效治疗失眠 的药物,从而完成了本发明。
[0004] 本发明的目的就是提供一种有效治疗失眠的中药组合药物。
[0005] 本发明的另一目的就是提供了该中药组合药物的制备方法。
[0006] 本发明是选择酸枣仁、党参、茯神、大枣、百合、琥珀、甘草、珍珠母、山楂、鹿茸、菟 丝子、远志、合欢皮、莱菔子、半夏、连翘、杜仲、木香、干姜、乳香、黄芪、白术、黄连、陈皮、石 菖蒲、人参、生地黄、牛膝、当归、肉桂、鸡血藤、何首乌、龙骨、桔梗、墨旱莲、仙鹤草药物进行 组合制备的,将这些药物组合使得各药物功效产生协同作用,从而能够有效治疗失眠。其中 选用酸枣仁是因为其性味甘,平,入心、脾、肝、胆经,有养肝,宁心,安神,敛汗的功能,治虚 烦不眠,惊悸怔忡,烦渴,虚汗。选用党参是因为其性味甘,平,入手、足太阴经气分,有补中 益气,生津的功能,治脾胃虚弱,气血两亏,体倦无力,食少,口渴,久泻,脱肛。选用茯神是因 为其性味甘淡,平,入心、脾经,有宁心,安神,利水的功能,治心虚惊悸,健忘,失眠,惊癎,小 便不利。选用大枣是因为其性味甘,温,入脾、胃经,有补脾和胃,益气生津,调营卫,解药毒 的功能,治胃虚食少,脾弱便溏,气血津液不足,营卫不和,心悸怔忡,妇人脏躁。选用百合是 因为其性味甘微苦,平,入心、肺经,有润肺止咳,清心安神的功能,治肺痨久嗽,咳唾痰血, 热病后余热未清,虚烦惊悸,神志恍惚,脚气浮肿。选用琥珀是因为其性味甘,平,入心、肝、 小肠经,有镇惊安神,散瘀止血,利水通淋的功能,治惊风癫癎,惊悸失眠,血淋血尿,小便不 通,妇女闭经,产后停瘀腹痛,痈疽疮毒,跌打创伤。选用甘草是因为其性味甘平,入脾、胃、 肺经,有和中缓急,润肺,解毒,调和诸药的功能,炙用治脾胃虚弱,食少,腹痛便溏,劳倦发 热,肺痿咳嗽,心悸,惊痈,生用治咽喉肿痛,消化性溃疡,痈疽疮疡,解药毒及食物中毒。选 用珍珠母是因为其性味咸,凉,入心、肝两经,有平肝,潜阳,定惊,止血的功能,治头眩,耳 鸣,心悸,失眠,癫狂,惊癎,吐血,衄血,妇女血崩。选用山楂是因为其性味酸甘,微温,入脾、 胃、肝经,有消食积,散瘀血,驱绦虫的功能,治肉积,癥瘕,痰饮,痞满,吞酸,泻痢,肠风,腰 痛,疝气,产后儿枕痛,恶露不尽,小儿乳食停滞。选用鹿茸是因为其性味甘、咸,温。归肝、肾 经,有补肾阳,益精血,强筋骨的功能,主治肾虚阳萎遗精,宫冷不孕,眩晕耳鸣,筋骨无力, 腰膝酸痛,崩漏带下,阴疽不敛。选用菟丝子是因为其性味辛甘,平,入肝、肾经,有补肝肾, 益精髓,明目的功能,治腰膝酸痛,遗精,消渴,尿有余沥,目暗。选用远志是因为其性味苦 辛,温,入心、肾经,有安神益智,祛痰,解郁的功能,治惊悸,健忘,梦遗,失眠,咳嗽多痰,痈 疽疮肿。选用合欢皮是因为其性味甘,平,入心、肝经,有解郁,和血,宁心,消痈肿的功能,治 心神不安,忧郁失眠,肺痈,痈肿,瘰疬,筋骨折伤。选用莱菔子是因为其性味辛甘,平,入肺、 胃经,有下气定喘,消食化痰的功能,治咳嗽痰喘,食积气滞,胸闷腹胀,下痢后重。选用半夏 是因为其性味辛,温,有毒,入脾、胃经,有燥湿化痰,降逆止呕,消痞散结的功能,治湿痰冷 饮,呕吐,反胃,咳喘痰多,胸膈胀满,痰厥头痛,头晕不眠,外消痈肿。选用连翘是因为其性 味苦,凉,入心、肝、胆经,有清热,解毒,散结,消肿的功能,治温热,丹毒,斑瘆,痈疡肿毒,瘰 疬,小便淋闭。选用杜仲是因为其性味甘微辛,温,入肝、肾经,有补肝肾,强筋骨,安胎的功 能,治腰脊酸疼,足膝痿弱,小便余沥,阴下湿痒,胎漏欲堕,高血压。选用木香是因为其性味 辛苦,温,入肺、肝、脾经,有行气止痛,温中和胃的功能,治中寒气滞,胸腹胀痛,呕吐,泄泻, 下痢里急后重,寒疝。选用款冬花是因为其性味辛,温,入肺经,有润肺下气,化痰止嗽的功 能,治咳逆喘息,喉痹。选用干姜是因为其性味辛,热,入脾、胃、肺经,有温中逐寒,回阳通脉 的功能,治心腹冷痛,吐泻,肢冷脉微,寒饮喘咳,风寒湿痹,阳虚吐、衄、下血。选用乳香是因 为其性味辛苦,温,入心、肝、脾经,有调气活血,定痛,追毒的功能,治气血凝滞,心腹疼痛, 痈疮肿毒,跌打损伤,痛经,产后瘀血刺痛。选用黄芪是因为其性味甘,微温,入肺、脾经,生 用有益卫固表,利水消肿,托毒,生肌的功能,治自汗,盗汗,血痹,浮肿,痈疽不溃或溃久敛; 炙用有补中益的功能,治内伤劳倦,脾虚泄泻,脱肛,气虚血脱,崩带及一切气衰血虚之症。 选用白术是因为其性味苦甘,温,入脾、胃经,有补脾,益胃,燥湿,和中的功能,治脾胃气弱, 不思饮食,倦怠少气,虚胀,泄泻,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。 选用黄连是因为其性味苦,寒,入心、肝、胃、大肠经,有泻火,燥湿,解毒,杀虫的功能,治时 行热毒、伤寒,热盛心烦,痞满呕逆,菌痢,热泻腹痛,肺结核,吐、衄、下血,消渴,疳积,蛔虫 病,百日咳,咽喉肿痛,火眼,口疮,痈疽疮毒,湿瘆,汤火烫伤。选用陈皮是因为其性味苦、 辛,温,归肺、脾经,有理气健脾,燥湿化痰的功能,治胸脘胀满,食少吐泻,咳嗽痰多。选用石 菖蒲是因为其性味辛苦,微温,入心、肝、脾经,有开窍,豁痰,理气,活血,散风,去湿的功能, 治癫癎,痰厥,热病神昏,健忘,气闭耳聋,心胸烦闷,胃痛,腹痛,风寒湿痹,痈疽肿毒,跌打 损伤。选用人参是因为其性味甘微甘,温,入脾、肺经,有大补元气,固脱生津,安神的功能, 治劳伤虚损,食少,倦怠,反胃吐食,大便滑泄,虚咳喘促,自汗暴脱,惊悸,健忘,眩晕头痛, 阳萎,尿频,消渴,妇女崩漏,小儿慢惊及久虚不复,一切气血津液不足之症。选用生地黄是 因为其性味甘,寒,归心、肝、肾经,有清热凉血,养阴,生津的功能,治热病烦渴,阴虚内热, 骨蒸劳热,内热消渴,吐血,衄血,发斑发瘆。选用牛膝是因为其性味甘苦酸,平,入肝、肾经, 生用散瘀血,消痈肿,治淋病,尿血,经闭,癥瘕,难产,胞衣不下,产后瘀血腹痛,喉痹,痈肿, 跌打损伤,熟用补肝肾,强筋骨,治腰膝骨痛,四肥拘挛,痿痹。选用当归是因为其性味甘辛, 温,入心、肝、脾经,有补血和血,调经止痛,润燥滑肠的功能,治月经不调,经闭腹痛,癥瘕结 聚,崩漏,血虚头痛,眩晕,痿痹,肠燥便难,赤痢后重,痈疽疮疡,跌扑损伤。选用肉桂是因为 其性味辛甘,热,入肾、脾、膀胱经,有补元阳,暖脾胃,除积冷,通血脉的功能,治命门火衰, 肢冷脉微,亡阳虚脱,腹痛泄泻,寒疝奔豚,腰膝冷痛,经闭癥瘕,阴疽,流注,及虚阳浮越,上 热下寒。选用鸡血藤是因为其性味苦甘,温,入心、脾二经,有活血、舒筋的功能,治腰膝酸 痛,麻木瘫痪,月经不调。选用何首乌是因为其性味苦甘涩,微温,入肝、肾经,有补肝,益肾, 养血,祛风的功能,治肝肾阴亏,发须早白,血虚头晕,腰膝软弱,筋骨酸痛,遗精,崩带,久 疟,久痢,慢性肝炎,痈肿,瘰疬,肠风,痔疾。选用龙骨是因为其性味甘涩,平,归入心、肝、 肾、大肠经,有镇惊安神,敛汗固精的功能,治惊癎癫狂,怔忡健忘,失眠多梦,自汗盗汗。选 用桔梗是因为其性味苦辛,平,入肺、胃经,有开宣肺气,祛痰排脓的功能,治外感咳嗽,咽喉 肿痛,肺痈吐脓,胸满胁痛,痢疾腹痛。选用墨旱莲是因为其性味苦酸,凉,入肝、肾经,有凉 血,止血,补肾,益阴的功能,治吐血,咳血,衄血,尿血,便血,血痢,刀伤出血,须发早白,白 喉,淋浊,滞下,阴部湿痒。选用仙鹤草是因为其性味苦辛,平,入肺、肝、脾经,有止血,健胃 的功能,治咯血,吐血,尿血,便血,赤白痢疾,崩漏带下,劳伤脱力,痈肿,跌打、创伤出血。
具体实施方式
[0007] 本发明组分的药物用量也是发明人经过大量摸索总结得出的,各组分的用量在下述重 量范围内都具有较好的疗效: 酸枣仁15-25克、党参10-20克、茯神5-15克、大枣10-20克、百合10-15克、琥珀10-20克、 甘草5-15克、珍珠母10-15克、山楂10-15克、鹿茸10-15克、菟丝子5-10克、远志5-15克、合欢 皮10-15克、莱菔子5-15克、半夏3-5克、连翘10-15克、杜仲5-10克、木香5-15克、干姜5-15 克、乳香10-15克、黄芪10-20克、白术10-15克、黄连5-15克、陈皮10-15克、石菖蒲10-15克、 人参10-20克、生地黄5-15克、牛膝5-10克、当归5-10克、肉桂10-20克、鸡血藤5-10克、何首 乌5-15克、龙骨10-20克、桔梗10-15克、墨旱莲10-15克、仙鹤草5-15克。
[0008] 优选为: 酸枣仁20克、党参15克、茯神10克、大枣15克、百合12克、琥珀15克、甘草10克、珍珠母12 克、山楂12克、鹿茸12克、菟丝子8克、远志10克、合欢皮12克、莱菔子10克、半夏3克、连翘12 克、杜仲8克、木香10克、干姜10克、乳香12克、黄芪15克、白术12克、黄连10克、陈皮12克、石 菖蒲12克、人参15克、生地黄10克、牛膝8克、当归8克、肉桂15克、鸡血藤8克、何首乌10克、龙 骨15克、桔梗12克、墨旱莲12克、仙鹤草10克。
[0009] 本发明药物的制备方法如下 一、备料 1、 酸枣仁:原药放入竹箩内,沉入清水缸中,使仁浮在水面,壳沉水底,将刺仁捞出,晒 干; 2、 党参:洗净泥沙后润透去芦,切片或切段,晒干; 3、 茯神:取原药材,除去杂质,洗净,润透,切成正方形的厚生或块,阴干; 4、 大枣:拣净杂质,晒干; 5、 百合:拣去杂质,黑瓣,簸除灰肩; 6、 琥珀:拣净杂质,用时捣碎研成细粉; 7、 甘草:拣去杂质,洗净,用水浸泡至八成透时,捞出,润透,切片,凉干; 8、 珍珠母:拣去杂质,敲成碎块,筛去灰肩; 9、 山楂:拣净杂质,筛去核; 10、 鹿茸:夏、秋两季将角锯下或砍下,经加工后,阴干或烘干。横切薄片,或据成碎块, 研成细粉用; 11、 菟丝子:过箩去净杂质,洗净,晒干; 12、 远志:拣去杂质,切段,筛去灰肩; 13、 合欢皮:清水浸泡洗净,捞出,闷润后先划成相等大的长条,再切块或切丝,干燥; 14、 莱菔子:簸去杂质,漂净泥土,捞出,晒干,用时捣碎; 15、 半夏:拣去杂质,筛去灰肩; 16、 连翘:拣净杂质,搓开,除去枝梗; 17、 杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干; 18、 木香:将原生药放清水内洗净,捞出,闷润12—24小时使软,切片,晒干; 19、 干姜:拣净杂质,用水浸泡3—6小时,捞出,闷润后切片或切成小方块,晒干; 20、 乳香:拣去砂子杂质; 21、 黄芪:拣净杂质,除去残留的根头和空心较大者,用水浸泡; 22、 白术:拣净杂质,用水浸泡,泡后捞出,润透,切片,晒干; 23、 黄连:拣去杂质,洗净泥砂,润透,切片,阴干; 24、 陈皮:取原药材,除去杂质及变黑的果皮,抢水洗净,润软,切丝,晒干或低温干燥, 筛去灰肩; 25、 石菖蒲:拣去杂质,洗净,稍稍浸泡,润透,切片,晒干; 26、 人参:除去芦头,切段即可; 27、 生地黄:取原药材,除去杂质,洗净,稍润,切厚片,干燥,筛去碎肩; 28、 牛膝:拣去杂质,洗净,润软,去芦,切段,晒干; 29、 当归:拣去杂质,洗净,闷润,稍晾,切片晒干; 30、 肉桂:拣净杂质,刮去粗皮,用时打碎,或刮去粗皮,用温开水浸润片刻,切片,晾干; 31、 鸡血藤:用水润透,切片,或蒸软后乘热切片,晒干; 32、 何首乌:拣去杂质,洗净,用水泡至八成透,捞出,润至内外湿度均匀,切片或切成方 块,晒干; 33、 龙骨:刷净泥土,打碎; 34、 桔梗:拣净杂质,除去芦头,洗净捞出,润透后切片,晒干; 35、 墨旱莲:拣净杂质,除去残根,洗净闷透,切段晒干; 36、 仙鹤草:除去杂质残根,洗净,润透,切断,晒干。
[0010] 二、制备 1、 将所述重量的酸枣仁、党参、茯神、大枣、百合、琥珀、甘草、珍珠母、山楂、鹿茸、菟丝 子、远志、合欢皮、莱菔子、半夏、连翘、杜仲、木香、干姜、乳香、黄苗、白术、黄连、陈皮、石菖 蒲、人参、生地黄、牛膝、当归、肉桂、鸡血藤、何首乌、龙骨、桔梗、墨旱莲、仙鹤草放入煎药容 器内,加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮 液,将第一次煎煮液倒入容器内; 2、 将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液; 3、 将两次煎煮液混合搅拌均匀,分为4剂服用。
[0011] 组方中酸率仁养肝,宁心,安神,敛汗,党参有补中益气,生津的功能二者为君药; 茯神宁心,安神,利水,大枣有补脾和胃,益气生津,调营卫,解药毒的功能,与百合、琥珀、甘 草为臣药,七味药共同发挥养肝、宁心安神、补中益气、补脾和胃、调营卫、解药毒、敛汗的作 用,治疗失眠效力全面,且以养肝、宁心安神、补中益气、补脾和胃为主,可治本;珍珠母有平 肝,潜阳,定惊,止血的功能与山楂、鹿茸、菟丝子、远志、合欢皮、莱菔子、半夏、连翘、杜仲、 木香、干姜、乳香、黄芪、白术、黄连、陈皮、石菖蒲、人参为佐药;生地黄清热凉血,养阴,生津 的功能与余下诸药为使药,是治标。
[0012] 本发明药物具有养肝、宁心安神、补中益气、补脾和胃、平肝潜阳、养阴生津的功 能,用于治疗失眠,疗程短、见效快、治愈后不复发。
[0013] 以下通过试验例来进一步阐述本发明所述药物的有益效果,这些试验例包括本发 明药物的动物毒性试验报告和临床疗效观察资料。
[0014] [试验例1]本发明药物的动物毒性试验报告: 取家兔30只,雌雄兼用,体重2.0—2.5kg,分两组,每组15只,其中一组为超剂量试验 组,另一组为正常量试验组。超常量组为20ml/kg,正常量为10ml/kg,给药方式为灌胃法给 药,每天两次,连服7天,每天观察给药反应,结果表明二组家兔活动、饮食正常,药物无不良 毒副作用。
[0015] [试验例2]本发明药物的临床疗效观察 1、一般资料 收治失眠门诊患者共30例。
[0016] 2、诊断标准 典型症状为:入睡困难、不能熟睡、早醒、睡后精力没恢复、容易惊醒等。
[0017] 3、治疗方法 选用上述药剂,给患者服用,每次服用1剂,每天早、晚各服1次,15天为一个疗程,连续 服用2个疗程。
[0018] 4、疗效评定标准 显效:失眠症状消失,恢复正常,疫愈; 好转:患者入睡困难、不能熟睡、早醒、睡后精力没恢复、容易惊醒的现象减轻,失眠症 状明显好转,逐步恢复正常; 无效:达不到好转标准者。
[0019] 5、治疗结果(见下表)
Figure CN108524888AD00081
在上述治疗中,用本发明药物治疗失眠患者30例,结果显效25例,显效率为83.33%,好 转4例,好转率为13.33%,无效1例,总有效率为96.66%。

Claims (3)

1. 一种治疗失眠的药物,其特征在于:它是由下列重量范围内的原料药制成: 酸枣仁15-25克、党参10-20克、茯神5-15克、大枣10-20克、百合10-15克、琥珀10-20克、 甘草5-15克、珍珠母10-15克、山楂10-15克、鹿茸10-15克、菟丝子5-10克、远志5-15克、合欢 皮10-15克、莱菔子5-15克、半夏3-5克、连翘10-15克、杜仲5-10克、木香5-15克、干姜5-15 克、乳香10-15克、黄芪10-20克、白术10-15克、黄连5-15克、陈皮10-15克、石菖蒲10-15克、 人参10-20克、生地黄5-15克、牛膝5-10克、当归5-10克、肉桂10-20克、鸡血藤5-10克、何首 乌5-15克、龙骨10-20克、桔梗10-15克、墨旱莲10-15克、仙鹤草5-15克。
2. 根据权利要求1所述的药物,其中各原料药的用量为: 酸枣仁20克、党参15克、茯神10克、大枣15克、百合12克、琥珀15克、甘草10克、珍珠母12 克、山楂12克、鹿茸12克、菟丝子8克、远志10克、合欢皮12克、莱菔子10克、半夏3克、连翘12 克、杜仲8克、木香10克、干姜10克、乳香12克、黄芪15克、白术12克、黄连10克、陈皮12克、石 菖蒲12克、人参15克、生地黄10克、牛膝8克、当归8克、肉桂15克、鸡血藤8克、何首乌10克、龙 骨15克、桔梗12克、墨旱莲12克、仙鹤草10克。
3. 根据权利要求1或2所述药物的制备方法,它包括下列步骤: (一)备料 (1) 酸枣仁:原药放入竹箩内,沉入清水缸中,使仁浮在水面,壳沉水底,将刺仁捞出,晒 干; (2) 党参:洗净泥沙后润透去芦,切片或切段,晒干; (3) 茯神:取原药材,除去杂质,洗净,润透,切成正方形的厚生或块,阴干; (4) 大枣:拣净杂质,晒干; (5) 百合:拣去杂质,黑瓣,簸除灰肩; (6) 琥珀:拣净杂质,用时捣碎研成细粉; (7) 甘草:拣去杂质,洗净,用水浸泡至八成透时,捞出,润透,切片,凉干; (8) 珍珠母:拣去杂质,敲成碎块,筛去灰肩; (9) 山楂:拣净杂质,筛去核; (10) 鹿鸾:夏、秋两季将角锯下或砍下,经加工后,阴干或烘干; (11) 菟丝子:过箩去净杂质,洗净,晒干; (12) 远志:拣去杂质,切段,筛去灰肩; (13) 合欢皮:清水浸泡洗净,捞出,闷润后先划成相等大的长条,再切块或切丝,干燥; (14) 莱菔子:簸去杂质,漂净泥土,捞出,晒干,用时捣碎; (15) 半夏:拣去杂质,筛去灰肩; (16) 连翘:拣净杂质,搓开,除去枝梗; (17) 杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干; (18) 木香:将原生药放清水内洗净,捞出,闷润12—24小时使软,切片,晒干; (19) 干姜:拣净杂质,用水浸泡3—6小时,捞出,闷润后切片或切成小方块,晒干; (20) 乳香:拣去砂子杂质; (21) 黄苗:拣净杂质,除去残留的根头和空心较大者,用水浸泡; (22) 白术:拣净杂质,用水浸泡,泡后捞出,润透,切片,晒干; (23) 黄连:拣去杂质,洗净泥砂,润透,切片,阴干; (24) 陈皮:取原药材,除去杂质及变黑的果皮,抢水洗净,润软,切丝,晒干或低温干燥, 筛去灰肩; (25) 石菖蒲:拣去杂质,洗净,稍稍浸泡,润透,切片,晒干; (26) 人参:除去芦头,切段即可; (27) 生地黄:取原药材,除去杂质,洗净,稍润,切厚片,干燥,筛去碎肩; (28) 牛膝:拣去杂质,洗净,润软,去芦,切段,晒干; (29) 当归:拣去杂质,洗净,闷润,稍晾,切片晒干; (30) 肉桂:拣净杂质,刮去粗皮,用时打碎,或刮去粗皮,用温开水浸润片刻,切片,瞭 干; (31) 鸡血藤:用水润透,切片,或蒸软后乘热切片,晒干; (32) 何首乌:拣去杂质,洗净,用水泡至八成透,捞出,润至内外湿度均匀,切片或切成 方块,晒干; (33) 龙骨:刷净泥土,打碎; (34) 桔梗:拣净杂质,除去芦头,洗净捞出,润透后切片,晒干; (35) 墨旱莲:拣净杂质,除去残根,洗净闷透,切段晒干; (36) 仙鹤草:除去杂质残根,洗净,润透,切断,晒干; (二)制备 (1) 将所述重量的酸枣仁、党参、茯神、大枣、百合、琥珀、甘草、珍珠母、山楂、鹿茸、菟丝 子、远志、合欢皮、莱菔子、半夏、连翘、杜仲、木香、干姜、乳香、黄苗、白术、黄连、陈皮、石菖 蒲、人参、生地黄、牛膝、当归、肉桂、鸡血藤、何首乌、龙骨、桔梗、墨旱莲、仙鹤草放入煎药容 器内,加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮 液,将第一次煎煮液倒入容器内; (2) 将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液; (3) 将两次煎煮液混合搅拌均匀,分为4剂服用。
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