CN103648482B - 阴道内递送系统 - Google Patents

阴道内递送系统 Download PDF

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Publication number
CN103648482B
CN103648482B CN201280035030.5A CN201280035030A CN103648482B CN 103648482 B CN103648482 B CN 103648482B CN 201280035030 A CN201280035030 A CN 201280035030A CN 103648482 B CN103648482 B CN 103648482B
Authority
CN
China
Prior art keywords
delivery system
intravaginal delivery
acid
intravaginal
eva
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280035030.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN103648482A (zh
Inventor
J·P·雷蒙
C·韦尔瓦埃特
H·韦斯特拉艾伦
M·特默尔曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Gent
Original Assignee
Universiteit Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiteit Gent filed Critical Universiteit Gent
Publication of CN103648482A publication Critical patent/CN103648482A/zh
Application granted granted Critical
Publication of CN103648482B publication Critical patent/CN103648482B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201280035030.5A 2011-07-15 2012-07-12 阴道内递送系统 Expired - Fee Related CN103648482B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11174103.9 2011-07-15
EP11174103 2011-07-15
PCT/EP2012/063702 WO2013010915A1 (en) 2011-07-15 2012-07-12 Intravaginal delivery system

Publications (2)

Publication Number Publication Date
CN103648482A CN103648482A (zh) 2014-03-19
CN103648482B true CN103648482B (zh) 2018-01-02

Family

ID=46579003

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280035030.5A Expired - Fee Related CN103648482B (zh) 2011-07-15 2012-07-12 阴道内递送系统

Country Status (5)

Country Link
US (1) US9168303B2 (enExample)
EP (1) EP2731587B1 (enExample)
JP (1) JP6010120B2 (enExample)
CN (1) CN103648482B (enExample)
WO (1) WO2013010915A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170319833A1 (en) * 2010-03-28 2017-11-09 Evestra, Inc. Intravaginal drug delivery device
CN104379111A (zh) * 2011-12-16 2015-02-25 维玛科合资有限公司 阴道药物递送器具和制造方法
CN104274388B (zh) * 2014-09-28 2017-02-15 南京泽恒医药技术开发有限公司 维生素c缓释栓剂组合物及制备方法
EP3559107B1 (en) * 2016-12-21 2023-12-13 Braskem S.A. Modified ethylene vinyl acetate compositions, polymer blends and films made therefrom
JP2021528452A (ja) * 2018-06-25 2021-10-21 タイタン ファーマシューティカルズ インコーポレイテッド インプラントとして使用するための装填可能な多孔質構造
KR102078462B1 (ko) * 2018-07-24 2020-02-17 주식회사 디네이쳐 질환경 개선 조성물 및 이를 포함하는 개선제
CN112569225B (zh) * 2019-09-27 2022-10-21 共生地球生物科技有限公司 非药物幽门杆菌杀菌组合物
KR20210097421A (ko) * 2020-01-30 2021-08-09 주식회사 디네이쳐 펄스형 질내 약산성 환경 유지 조성물
CA3167761C (en) * 2020-02-12 2025-05-20 Shenzhen Eulikan Biotechnology Co Ltd BACTERIOSTATIC COMPOSITION, PREPARATION PROCESS AND USE

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101849936A (zh) * 2004-06-17 2010-10-06 金伯利-克拉克环球有限公司 阴道保健产品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5543150A (en) * 1993-09-15 1996-08-06 Columbia Laboratories, Inc. Method of progesterone delivery and affect thereof
ATE461681T1 (de) 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
WO2006065873A2 (en) 2004-12-14 2006-06-22 Poly-Med, Inc. Intravaginal ringed mesh device and applicator therefor
TW200927141A (en) 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
WO2009129459A1 (en) * 2008-04-18 2009-10-22 Combinent Biomedical Systems, Inc. Devices that include ethylene-vinyl acetate copolymers and methods of making and using same
FI20095550A0 (fi) 2009-05-19 2009-05-19 Bayer Schering Pharma Oy Vaginaalinen antojärjestelmä
KR101993786B1 (ko) * 2010-11-12 2019-06-28 더 유니버시티 오브 유타 리서치 파운데이션 윤활제의 제어된 전달을 위한 질내 장치

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101849936A (zh) * 2004-06-17 2010-10-06 金伯利-克拉克环球有限公司 阴道保健产品

Also Published As

Publication number Publication date
CN103648482A (zh) 2014-03-19
EP2731587B1 (en) 2024-12-04
EP2731587A1 (en) 2014-05-21
JP6010120B2 (ja) 2016-10-19
US20140154293A1 (en) 2014-06-05
JP2014520871A (ja) 2014-08-25
US9168303B2 (en) 2015-10-27
WO2013010915A1 (en) 2013-01-24

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