CN103622864A - Multifunctional aloe gel and preparation method thereof - Google Patents

Multifunctional aloe gel and preparation method thereof Download PDF

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Publication number
CN103622864A
CN103622864A CN201310033975.XA CN201310033975A CN103622864A CN 103622864 A CN103622864 A CN 103622864A CN 201310033975 A CN201310033975 A CN 201310033975A CN 103622864 A CN103622864 A CN 103622864A
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skin
aloe
sodium
functional
aloe glue
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庞义
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GUANGDONG YALGET FINE CHEMICAL Co Ltd
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GUANGDONG YALGET FINE CHEMICAL Co Ltd
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Priority to CN201310033975.XA priority Critical patent/CN103622864A/en
Priority to PCT/CN2013/001490 priority patent/WO2014117316A1/en
Publication of CN103622864A publication Critical patent/CN103622864A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • Birds (AREA)
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  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses multifunctional aloe gel and a preparation method thereof. Formerly conventional aloe gel products cannot maintain good skin quality and cannot reach multiple beauty-maintaining skin-care effects. The multifunctional aloe gel provided by the invention comprises effective active components such as aloe freeze-dried powder, plant extract, compounded sodium hyaluronate, allantoin, D-panthenol, menthol, betaine, beta-glucan and the like, employs methylisothiazolinone combined with iodopropynyl butylcarbamate as an antiseptic, and employs an alkali liquid selected from solutions of potassium hydroxide or sodium hydroxide with the concentration of 5%. The product prepared by employing the preparation method provided by the invention has the good efficacy of retaining moisture, calming, resisting ageing, resisting inflammation and bacteria, alleviating stimulation, compacting skin, promoting healing of damaged skin, and the like, and is mild in properties, safe to use and excellent in moisture-retaining performance. The simultaneous usage of the multiple components not only gives full play to the effective effects of each component, but also helps to guarantee the best beauty-maintaining skin-care effect of the integral product.

Description

Multi-functional Aloe glue and preparation method thereof
Technical field
The present invention relates to a kind of Aloe glue, particularly a kind of multi-functional Aloe glue and preparation method thereof.
Background technology
Along with the beauty functions of Aloe is subject to people's approval gradually, to the research and development of its effective ingredient and effect also progressively deeply.At present, Aloe skin care item kind is on the market a feast for the eyes, and moisturizing is as a kind of basic function of skin protection cosmetics, selects to have superior moisture-retaining capacity and the lasting wetting agent of effect, it is maintained to the good skin quality of skin most important.Conventionally, for increasing the moisture-keeping efficacy of skin care item, wetting agent can be added in formula for a product, as glycerol, propylene glycol, sorbitol, 1, the polyhydric alcohol such as 3-butanediol, separately have unique water conservation lubricating function nature moisturizing factor---hyaluronate sodium is also added in high-grade cosmetics conventionally.But conventional hyaluronic acid is polymer hyaluronic acid, its molecular weight be hundreds of thousands arrive up to a million more than.Only add common conventional hyaluronic acid, the more difficult multiple moistening effect that makes consumer satisfaction that reaches.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of character gentleness, use safely, have multi-functional Aloe glue of superior cosmetology effect and preparation method thereof.
The technical solution adopted for the present invention to solve the technical problems is: multi-functional Aloe glue, by weight percentage, comprises following component:
Aloe frozen-dried powder 0.10 ~ 1.50%, Herba portulacae extract 0.00% ~ 10.00%, polymer hyaluronic acid sodium 0.00% ~ 1.00%, oligomerization hyaluronate sodium 0.00% ~ 1.00%, allantoin 0.00% ~ 0.40%, D-panthenol 0.00% ~ 5.00%, betanin 0.00% ~ 5.00%, beta glucan 0.10% ~ 3.00%, 1,3 butylene glycol 1.00% ~ 15.00%, Mentholum 0.00% ~ 1.00%, carbomer 0.10% ~ 2.00%, essence 0.00%-0.30%, antiseptic 0.00% ~ 0.30%, alkali liquor 0.10% ~ 10.00%, deionized water 10.00% ~ 90.00%.
Multi-functional Aloe glue, described oligomerization hyaluronate sodium is the low-molecular-weight hyaluronate sodium that the molecular weight that made by enzyme cutting method is 3000 ~ 10000.
Multi-functional Aloe glue, described betanin is the betanin of cosmetics-stage or pharmaceutical grade.
Multi-functional Aloe glue, described antiseptic is one or both mixing in Methylisothiazolinone and iodo propinyl ammonia butyl formate.
Multi-functional Aloe glue, described alkali liquor is a kind of in potassium hydroxide or sodium hydroxide solution.
Multi-functional Aloe glue, described alkali liquor is that concentration is a kind of in 5% potassium hydroxide or sodium hydroxide solution.
The preparation method of multi-functional Aloe glue, comprises the following steps:
It is standby that A takes each component by weight percentage;
B is by appropriate water dissolution for aloe frozen-dried powder, stand-by;
C polymer hyaluronic acid sodium, oligomerization hyaluronate sodium, deionized water, allantoin, D-panthenol, betanin, beta glucan, carbomer drop into respectively in emulsifying pot, evacuation, with 30 revs/min-50 revs/min, mix and blend, be heated to after 70 ℃ of temperature simultaneously, control heating, continue to stir until after dissolving completely, be cooled to temperature 50 C, add product and Herba portulacae extract described in B step, evacuation, 30 revs/min of stirrings, continue to be cooled to temperature to drop to below 45 ℃;
D drops into emulsifying pot by 1,3 butylene glycol, Mentholum, antiseptic, essence mix homogeneously and after dissolving, and stirs 5 minutes, until dissolve completely and mix homogeneously;
It is 5% alkali liquor that E adds concentration, stirs and is cooled to below 40 ℃;
F discharging.
The invention has the beneficial effects as follows: multi-functional Aloe glue of the present invention is owing to containing aloe frozen-dried powder, plant extract, hyaluronate sodium, allantoin, D-panthenol, Mentholum, betanin, the effective active compositions such as beta glucan, that a kind of character is gentle, use safety, there is superior performance of keeping humidity, can use separately the skin effect of performance Aloe self, can use with other multiple skin-protection product collocation the multi-functional Aloe glue of the multiple cosmetology effect of performance Aloe again, wherein, Aloe has sun-proof, moisturizing, analgesia, anti-inflammation, pre-anti-acne, the effects such as healing shallow wound, Herba portulacae extract has the effects such as antiallergic, irritation, antiinflammatory anti-acne, composite hyaluronate sodium is the mixture of polymer hyaluronic acid sodium and oligomerization hyaluronate sodium, polymer hyaluronic acid sodium has good film property, can pin skin top layer moisture, the skin that compacts, and oligomerization hyaluronate sodium has rapid osmotic, deep moisturizing, reduce the effects such as skin wrinkle, allantoin has skin moistening, crease-resistant, horny layer softening albumen, stimulates tissue growth, promotes the effects such as wound healing, D-panthenol has the effects such as antiinflammatory, moisturizing, promotion wound healing, the effects such as that Mentholum has is antipruritic, antiallergic, reducing swelling and alleviating pain, antiphlogistic antibacterial, betanin can improve the moisture holding capacity of skin, activated cell vigor, have keep skin moist, smooth, prevent effect dry and that shade, and beta glucan has the effects such as moisturizing, defying age, antiallergic antiinflammatory, antagonism uv damage, the healing that promotes cicatrix and regeneration, various ingredients is used simultaneously, can give full play to the effect unique of each component, can guarantee again the optimum efficiency of integral product.
The specific embodiment
Multi-functional Aloe glue, by weight percentage, comprises following component:
Aloe frozen-dried powder 0.10 ~ 1.50%, Herba portulacae extract 0.00% ~ 10.00%, polymer hyaluronic acid sodium 0.00% ~ 1.00%, oligomerization hyaluronate sodium 0.00% ~ 1.00%, allantoin 0.00% ~ 0.40%, D-panthenol 0.00% ~ 5.00%, betanin 0.00% ~ 5.00%, beta glucan 0.10% ~ 3.00%, 1,3 butylene glycol 1.00% ~ 15.00%, Mentholum 0.00% ~ 1.00%, carbomer 0.10% ~ 2.00%, essence 0.00%-0.30%, antiseptic 0.00% ~ 0.30%, alkali liquor 0.10% ~ 10.00%, deionized water 10.00% ~ 90.00%.Wherein aloe frozen-dried powder selects Aloe vulgaris lyophilized powder as main effect raw material, and in this Aloe, the effective ingredient such as contained barbaloin, aminoacid, mucopolysaccharide makes it have superior cosmetology effect; On the skin protection basis of Aloe, by the composite of plurality of active ingredients such as Herba portulacae extract, D-panthenol and beta glucans, add, make the effect such as bactericidal antiphlogistic, antiallergic, defying age, the healing of promotion damaged skin of the multi-functional Aloe glue of the present invention obtain strengthening, can increase the resistance of damaged skin to alien bacteria, can promote epidermal cell proliferation again, contribute to the skin regeneration of damaged part.And in the selection of wetting agent, the present invention has selected the hyaluronate sodium of two kinds of different molecular weights---and polymer hyaluronic acid sodium and oligomerization hyaluronate sodium are as wetting agent, the hyaluronate sodium molecular energy of high molecular forms ventilative hydration shell at skin surface, make horny layer hydration softening, increase horny layer absorbing active substance; And oligomerization hyaluronate sodium can directly infiltrate skin corium, the supply of expansion blood capillary, increase blood microcirculation, reinforced nutrition matter, the common cooperation by both, reaches more comprehensive, three-dimensional moistening effect.And the 1,3 butylene glycol adding in the present invention, allantoin and betanin, can make skin keep moistening from atmosphere and deep skin absorption moisture, and improve the moisture holding capacity of skin, further promoted its water-absorbing-retaining effect, wherein 1,3 butylene glycol also has good bacteriostasis.In addition, the present invention selects carbomer as gel, has the feature of water-soluble base, release rapidly, without greasy, to skin and mucosa nonirritant, during use, can form protecting film at skin surface, the infringement of isolated external contaminant to skin.In addition, for avoiding triethanolamine in the serious zest of impurity to skin such as the residual diethanolamine of building-up process, nitrosamine, the present invention has selected potassium hydroxide or sodium hydroxide solution that concentration is 5% wherein a kind of as nertralizer, make acid carbomer salify, curling molecule opens and thickening, thereby regulates stability and the viscosity of preparation.In the selection of antiseptic, the present invention uses Methylisothiazolinone together in conjunction with iodo propinyl ammonia butyl formate, can effectively prevent cosmetics putrid and deteriorated and secondary pollution before the deadline, to guarantee the safety and stability of product.Experiment showed, multi-functional Aloe glue stable in properties of the present invention, compatible good, gel tissue is fine and smooth evenly, foreign, fragrance up to specification, even if also there will not be lamination under the condition of high temperature and low temperature.In addition, the indices such as its pH value, bacterial content and content of beary metal all meets the prescription of skin care item.
Multi-functional Aloe glue, described oligomerization hyaluronate sodium is the low-numerator sodium hyaluronate that the molecular weight that made by enzyme cutting method is 3000 ~ 10000; In common cosmetology product, substantially all only adopted high molecular weight hyaluronic acid to receive, and the present invention has selected the hyaluronate sodium of two kinds of different molecular weights---polymer hyaluronic acid sodium and oligomerization hyaluronate sodium are as wetting agent, the hyaluronate sodium molecular energy of high molecular forms ventilative hydration shell at skin surface, make horny layer hydration softening, increase horny layer absorbing active substance; And oligomerization hyaluronate sodium can directly infiltrate skin corium, the supply of expansion blood capillary, increase blood microcirculation, reinforced nutrition matter, the common cooperation by both, reaches more comprehensive, three-dimensional moistening effect.
Multi-functional Aloe glue, described betanin belongs to the betanin of cosmetics-stage or pharmaceutical grade, betanin can improve the moisture holding capacity of skin, activated cell vigor, have keep skin moist, smooth, prevent effect dry and that shade;
Multi-functional Aloe glue, described antiseptic is one or both mixing in Methylisothiazolinone and iodo propinyl ammonia butyl formate; The present invention uses Methylisothiazolinone together in conjunction with iodo propinyl ammonia butyl formate, can effectively prevent cosmetics putrid and deteriorated and secondary pollution before the deadline, to guarantee the safety and stability of product;
Multi-functional Aloe glue, described alkali liquor is that concentration is a kind of in 5% potassium hydroxide or sodium hydroxide solution, for avoiding triethanolamine in the serious zest of impurity to skin such as the residual diethanolamine of building-up process, nitrosamine, the present invention has selected potassium hydroxide or sodium hydroxide solution that concentration is 5% wherein a kind of as nertralizer, make acid carbomer salify, curling molecule opens and thickening, thereby regulates stability and the viscosity of preparation.
The preparation method of multi-functional Aloe glue, comprises the following steps:
It is standby that A takes each component by weight percentage;
B is by appropriate water dissolution for aloe frozen-dried powder, stand-by;
C polymer hyaluronic acid sodium, oligomerization hyaluronate sodium, deionized water, allantoin, D-panthenol, betanin, beta glucan, carbomer drop into respectively in emulsifying pot, evacuation, with 30 revs/min-50 revs/min, mix and blend, be heated to after 70 ℃ of temperature simultaneously, control heating, continue to stir until after dissolving completely, be cooled to temperature 50 C, add product and Herba portulacae extract described in B step, evacuation, with 30 revs/min of stirrings, continues to be cooled to temperature to drop to below 45 ℃;
D drops into emulsifying pot by 1,3 butylene glycol, Mentholum, antiseptic, essence mix homogeneously and after dissolving, and stirs 5 minutes, until dissolve completely and mix homogeneously;
It is 5% alkali liquor that E adds concentration, stirs and is cooled to below 40 ℃;
F discharging.
Embodiment mono-:
By 10 kilograms of multi-functional Aloe glue finished products, take various compositions:
10 grams of aloe frozen-dried powders, 100 grams of Herba portulacae extracts, 10 grams, polymer hyaluronic acid sodium, 5 grams of oligomerization hyaluronate sodiums, 15 grams of allantoin, 50 grams of D-panthenol, 100 grams of betanins, 10 grams of beta glucans, 500 grams of 1,3 butylene glycols, 60 grams of carbomers, 1 gram of Methylisothiazolinone, 5 grams of iodo propinyl ammonia butyl formates, 500 grams of 5% potassium hydroxide solutions, 8624 grams of deionized waters are standby; First polymer hyaluronic acid sodium, oligomerization hyaluronate sodium, deionized water, allantoin, D-panthenol, betanin, beta glucan, carbomer are dropped into respectively in emulsifying pot, evacuation, with 30 revs/min-50 revs/min, mix and blend, be heated to after 70 ℃ of temperature simultaneously, control heating, continue to stir until after dissolving completely, be cooled to temperature 50 C, add product and Herba portulacae extract described in B step, evacuation, with 30 revs/min of stirrings, continues to be cooled to temperature to drop to below 45 ℃; By 1,3 butylene glycol, Mentholum, antiseptic, essence mix homogeneously and after dissolving, drop into emulsifying pot again, stir 5 minutes, until dissolve completely and mix homogeneously; Then adding concentration is 5% alkali liquor, stirs and is cooled to below 40 ℃; Discharging.
Embodiment bis-:
By 10 kilograms of multi-functional Aloe glue finished products, take various compositions:
40 grams of aloe frozen-dried powders, 200 grams of Herba portulacae extracts, 5 grams, polymer hyaluronic acid sodium, 20 grams of oligomerization hyaluronate sodiums, 10 grams of allantoin, 50 grams of D-panthenol, 100 grams of betanins, 10 grams of beta glucans, 500 grams of 1,3 butylene glycols, 1 gram of Mentholum, 120 grams of carbomers, 1 gram of Methylisothiazolinone, 5 grams of iodo propinyl ammonia butyl formates, 1000 grams of 5% potassium hydroxide solutions, 7763 grams of deionized waters are standby; First polymer hyaluronic acid sodium, oligomerization hyaluronate sodium, deionized water, allantoin, D-panthenol, betanin, beta glucan, carbomer are dropped into respectively in emulsifying pot, evacuation, with 30 revs/min-50 revs/min, mix and blend, be heated to after 70 ℃ of temperature simultaneously, control heating, continue to stir until after dissolving completely, be cooled to temperature 50 C, add product and Herba portulacae extract described in B step, evacuation, with 30 revs/min of stirrings, continues to be cooled to temperature to drop to below 45 ℃; By 1,3 butylene glycol, Mentholum, antiseptic, essence mix homogeneously and after dissolving, drop into emulsifying pot again, stir 5 minutes, until dissolve completely and mix homogeneously; Then adding concentration is 5% alkali liquor, stirs and is cooled to below 40 ℃; Discharging.
Embodiment tri-:
By 10 kilograms of multi-functional Aloe glue finished products, take various compositions:
50 grams of aloe frozen-dried powders, 100 grams of Herba portulacae extracts, 50 grams of oligomerization hyaluronate sodiums, 20 grams of allantoin, 300 grams of betanins of D-panthenol, 300 grams, 10 grams of beta glucans, 300 grams of 1,3 butylene glycols, 130 grams of carbomers, 1 gram of Methylisothiazolinone, 5 grams of iodo propinyl ammonia butyl formates, 5 grams, essence, 1100 grams of 5% potassium hydroxide solutions, 7635 grams of deionized waters are standby; First polymer hyaluronic acid sodium, oligomerization hyaluronate sodium, deionized water, allantoin, D-panthenol, betanin, beta glucan, carbomer are dropped into respectively in emulsifying pot, evacuation, with 30 revs/min-50 revs/min, mix and blend, be heated to after 70 ℃ of temperature simultaneously, control heating, continue to stir until after dissolving completely, be cooled to temperature 50 C, add product and Herba portulacae extract described in B step, evacuation, with 30 revs/min of stirrings, continues to be cooled to temperature to drop to below 45 ℃; By 1,3 butylene glycol, Mentholum, antiseptic, essence mix homogeneously and after dissolving, drop into emulsifying pot again, stir 5 minutes, until dissolve completely and mix homogeneously; Then adding concentration is 5% alkali liquor, stirs and is cooled to below 40 ℃; Discharging.
In a word, three embodiment of the present invention are the specific embodiment of three arbitrary datas in protection domain of the present invention, the product property finally obtaining is stable, compatible good, gel tissue is fine and smooth evenly, foreign, fragrance up to specification, even if also there will not be lamination under the condition of high temperature and low temperature; In addition, the indices such as its pH value of product of the present invention, bacterial content and content of beary metal all meets the prescription of skin care item after tested; Any other replaces the similar formula of each component all within protection scope of the present invention with the identical equivalents of character.

Claims (7)

1. multi-functional Aloe glue, by weight percentage, comprises following component:
Aloe frozen-dried powder 0.10 ~ 1.50%, Herba portulacae extract 0.00% ~ 10.00%, polymer hyaluronic acid sodium 0.00% ~ 1.00%, oligomerization hyaluronate sodium 0.00% ~ 1.00%, allantoin 0.00% ~ 0.40%, D-panthenol 0.00% ~ 5.00%, betanin 0.00% ~ 5.00%, beta glucan 0.10% ~ 3.00%, 1,3 butylene glycol 1.00% ~ 15.00%, Mentholum 0.00% ~ 1.00%, carbomer 0.10% ~ 2.00%, essence 0.00%-0.30%, antiseptic 0.00% ~ 0.30%, alkali liquor 0.10% ~ 10.00%, deionized water 10.00% ~ 90.00%.
2. multi-functional Aloe glue according to claim 1, is characterized in that described oligomerization hyaluronate sodium is the low-molecular-weight hyaluronate sodium that the molecular weight that made by enzyme cutting method is 3000 ~ 10000.
3. multi-functional Aloe glue according to claim 1, is characterized in that described betanin is the betanin of cosmetics-stage or pharmaceutical grade.
4. multi-functional Aloe glue according to claim 1, is characterized in that described antiseptic is one or both mixing in Methylisothiazolinone and iodo propinyl ammonia butyl formate.
5. multi-functional Aloe glue according to claim 1, is characterized in that described alkali liquor is a kind of in potassium hydroxide or sodium hydroxide solution.
6. multi-functional Aloe glue according to claim 1, is characterized in that described alkali liquor is that concentration is a kind of in 5% potassium hydroxide or sodium hydroxide solution.
7. the preparation method of multi-functional Aloe glue, comprises the following steps:
It is standby that A takes each component by weight percentage;
B is by appropriate water dissolution for aloe frozen-dried powder, stand-by;
C polymer hyaluronic acid sodium, oligomerization hyaluronate sodium, deionized water, allantoin, D-panthenol, betanin, beta glucan, carbomer drop into respectively in emulsifying pot, evacuation, with 30 revs/min-50 revs/min, mix and blend, be heated to after 70 ℃ of temperature simultaneously, control heating, continue to stir until after dissolving completely, be cooled to temperature 50 C, add product and Herba portulacae extract described in B step, evacuation, with 30 revs/min of stirrings, continues to be cooled to temperature to drop to below 45 ℃;
D drops into emulsifying pot by 1,3 butylene glycol, Mentholum, antiseptic, essence mix homogeneously and after dissolving, and stirs 5 minutes, until dissolve completely and mix homogeneously;
It is 5% alkali liquor that E adds concentration, stirs and is cooled to below 40 ℃;
F discharging.
CN201310033975.XA 2013-01-30 2013-01-30 Multifunctional aloe gel and preparation method thereof Pending CN103622864A (en)

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PCT/CN2013/001490 WO2014117316A1 (en) 2013-01-30 2013-12-05 Multi-function aloe gel and preparation method thereof

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