CN103599062A - Eye cream and preparation method thereof - Google Patents
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Abstract
The invention discloses an eye cream and a preparation method thereof. The eye cream is fine and smooth, the color is uniform, and the flavor is pure. On the basis of an antioxidant network system, active ingredients such as a polysaccharides skin toner, beta-glucan, transparent hyaluronic acid, resveratrol and the like are added, and multiple traditional Chinese herb extracts such as frankincense, Tuckahoe, rhodiola rosea and the like are compounded, so that the eye cream has a strong antioxidant function, a strong moistening function and a strong skin toning function. Multiple active ingredients are matched with each other and are in synergistic interaction with each other, so that eye wrinkles can be improved, dark circles can be smoothed, the eye contour can be toned, and eyes can be restored in good color.
Description
Technical field
The present invention relates generally to a kind of eye cream, belongs to cosmetic field.
Background technology
Skin aging is by endogenous factor and the coefficient result of extrinsic factor.The highly chemically active free radical that has wherein producing in organism metabolism process is old and feeble important startup factor.Free radical is a kind of asymmetric, unsettled atom or molecule forming because losing an electronics, there is very large energy, the materials such as lipid, protein, saccharide and DNA in can attack cells tissue, attempt is captured an electronics in the hope of rebalancing, this just caused the oxidation of lipid and saccharide, the inactivation of the degeneration of protein, enzyme, the cut-out of DNA structure, base change etc., thereby cause the damage of cell membrane, genetic factor etc., and then bring out various diseases, canceration, organism aging process etc.Be subject to for a long time the extrinsic factors such as ultraviolet radiation, environmental pollution and smoke from cigarette also all can produce a large amount of free radicals, cause skin aging.
Antioxidant can be by suppressing free-radical generating or removing and trapping free radical, free chain reaction is interrupted and reaches antioxidation object.By its chemical constitution, can be divided into enzyme and non-enzyme antioxidant, enzyme antioxidant comprises superoxide dismutase (SOD), catalase, coenzyme Q10 (CoQ10) and DNA/RNA repairase etc.; Non-enzyme antioxidant is as materials such as vitamin A (VA), vitamin C (VC), vitamin E (VE), beta-carotene, alpha-lipoic acid (LA), glutathion (GSH) and zinc, selenium.Antioxidant is for cosmetics, both can suppress active substance and nutritional labeling invades or photocatalysis generation oxidation deterioration through antibacterial in air, again can with cosmetics in other active component jointly play a role, play moisturizing, reduce wrinkle, the anti-ageing effect of waiting for a long time.
Research discovery, the antioxidant activity of some composite antioxidant is higher than each component in the active sum of adding under concentration, and multiple antioxidant is combined use, and its effect is often greater than the effect of using with the single antioxidant of dosage.Between antioxidant content, often there is antioxidation synergism, and synergism is affected by concentration, reaction system of antioxidant etc.The scholars such as the famous professor of Univ California-Berkeley, international free radical chairman doctor LestPaker of association have proposed free radical scavenger chain reaction and antioxidant network technology, clear and clearly by their analogies for efficient antidotal latest modern technological pattern.In this antioxidant series or antioxidant network, VC, VE, CoQ10, LA, GSH are drafted core and the essence for antioxidant network technology, and its reason mainly contains: the first, and body can not produce VC and VE, must from food, obtain; The second, although body can produce GSH, LA and CoQ10 voluntarily, they in vivo level decline with age and obviously; The 3rd, these 5 kinds of antioxidants have wide spectrum, efficient radical scavenging activity, and can mutually supplement each other, Synergistic; The 4th, network freedom base scavenger or Network Antioxidants respectively have it to be different from the unique effect of other free radical scavenger or antioxidant; The 5th, between these 5 kinds of network freedom base scavengers or Network Antioxidants, exist and interact in vivo, and can mutually regenerate, make to enter each other recirculation, formed
| Raw material | w% | Raw material | w% |
Network, has greatly strengthened the function of antioxidant, and this network is the main defence line of resisting the toxic damages of free radical mediated in living things system, finally at slow down aging with in improving the process of body resistance against diseases, is bringing into play particular utility.
Antioxidation chain reaction and antioxidant network technology have become at present the modern pattern of antioxidation, defying age with innovating all the fashion in the world.According to this network technology and pattern, can develop various dissimilar skin anti-aging cosmetics, and 5 kinds of antioxidant networks are bound to play a positive role and complementary advantage in anti-aging cosmetics use procedure, make skin anti-aging show more obvious characteristic, produce more significant effect.
The eyes are the windows of the mind, the age that also can reveal women.With advancing age, the worry of eye skin can be than any one position is all many on the face.Eye part skin is thin, and fat content is few, lack flexibility fiber and collagen structure, and can make eye skin be subject to continuous stretching nictation frequently; In addition daily life system is irregular, dim, lax with the eye eye part skin that all easily causes such as improper, just there will be the problems such as black eye, eye pouch, crows-feet, and dry skin person is more prone to the sign of above-mentioned aging.Eye cream is mainly for dry skin person design, more salubriouser, fine and smooth than facial cream, has both been easy to be absorbed by eye part skin, can suitably supplement oil content again, has moisturizing, moistens, calms down the effects such as microgroove.
At present, on market, eye cream is various in style, but there is not yet, Chinese herbal medicine extract and antioxidant network system is combined and is applied to the commodity in eye cream.It is guidance that the theoretical and emulsion theory of antioxidant network system is take in the present invention, multiple additive and the Chinese herbal medicine extract with antioxidant activity carried out composite, add efficient moisture-retention agent, Firm agent simultaneously, develop there is moisturizing, the eye cream of crease-resistant, the multi-efficiency such as compact; To the sense organ of this eye cream and physical and chemical index, moisture retention, non-oxidizability and to crease-resistant effect of compacting of skin near the eyes etc., test simultaneously.
Summary of the invention
The object of the invention is just to provide a kind of eye cream and preparation method thereof.
The present invention is achieved by the following technical solutions:
An eye cream, is characterized in that the formula of described eye cream is:
A phase and B are placed in respectively to 70-75 ℃ of water-bath mutually and stir 25-30min, decorating film is dissolved, then the F having dissolved is added to A it is uniformly dispersed in mutually, then while stirring B is added to; After rapid stirring 25-30min, lower the temperature, while being cooled to 40-45 ℃, C phase, D phase and E added respectively mutually and be stirred to evenly, temperature stops while being down to 30-35 ℃ stirring, and discharging, obtains described eye cream.
A preparation method for eye cream for making manufactured goods total amount remain 100g, adds appropriate distilled water in preparation process when adding each phase again.
Advantage of the present invention is:
It is oil phase raw material that eye cream of the present invention be take type siloxane, synthetic squalane, caprylic/capric triglyceride etc.,
| Raw material | w% | Raw material | w% |
Moist, smooth, ventilative, give skin around the eyes as the sensation as silk; Add the materials such as hyaluronate sodium, pantothenylol and avenabeta glucosan with remarkable enrich the water, moisturizing and barrier function that can momentary recovery skin, the inherent water cycle of balance adjustment skin also improves coarse skin quality; Centered by antioxidant network system, composite Radix Rhodiolae extract, the antioxidant that resveratrol isoreactivity is stronger, have wide spectrum, efficient radical scavenging activity, and energy Synergistic, regeneration, makes to enter each other recirculation mutually, has greatly strengthened the function of antioxidant; It is lax that the agent of polysaccharide Firm suppresses eye, allows eye skin plastotype compact, and has raising resistance simultaneously, promotes cell enlargement, the effect of antiinflammatory; Poria extract energy consumer edema, highlights near the eyes; Olibanum extract have invigorate blood circulation, antiinflammatory, removal black eye and the effects such as skin of compacting; Radix Astragali extract can promote the synthetic of collagen protein; Radix Angelicae Sinensis extract can blood circulation promoting and blood stasis dispelling, has prevention and removes black-eyed effect.
Eye cream mastic of the present invention is fine and smooth, color and luster is even.Part active component adopt nanoemulsions, liposome and and microcapsule technology, be both beneficial to the transmission of active component and the absorption of skin, increased again the stability of product.Soft in formula, essence, parabens, gentle non-stimulated.Various active composition cooperatively interacts, and Synergistic can improve eye wrinkle-removing, Vitamin K, the profile near the eyes that compacts, and it is color that the two pupils of order are replied radiating power and vitality god.
Accompanying drawing explanation
Fig. 1 is the microphotograph (* 400) of eye cream sample of the present invention;
Fig. 2 is the hydroscopicity temporal evolution graph of a relation of eye cream;
Fig. 3, for trier uses 30 minutes front and back contrast photos of eye cream, is (a) before using; (b) for using after 15 minutes; (c) for using after 30 minutes.
Fig. 4 be respectively 42 years old and 26 years old, dry skin two ages experimenter before use with use after 90 days the comparison diagram of skin near the eyes, be (a) before 42 years old trier uses; (b) be that 42 years old trier used after 90 days; (c) be before 26 years old trier uses; (d) be that 26 years old trier used after 90 days.
The specific embodiment
Embodiment 1
An eye cream, is characterized in that the formula of described eye cream is:
A preparation method for eye cream, comprises the following steps:
A phase and B are placed in respectively to 70-75 ℃ of water-bath mutually and stir 25-30min, decorating film is dissolved, then the F having dissolved is added to A it is uniformly dispersed in mutually, then while stirring B is added to; After rapid stirring 25-30min, lower the temperature, while being cooled to 40-45 ℃, C phase, D phase and E added respectively mutually and be stirred to evenly, temperature stops while being down to 30-35 ℃ stirring, and discharging, obtains described eye cream.
Performance test:
Testing graininess
Take a morsel eye cream sample on microscope slide, and covered, rolls and is evenly placed on micro-Microscopic observation and takes pictures.Microscope amplification is 400 times.
Antioxidation test
Take 0.5g eye cream, after dissolving, proceed to standardize solution in 100mL volumetric flask with pure water, making mass concentration is 5.00 * 10
-3the sample solution of g/mL.
Compound concentration is 2 * 10 respectively
-4the ethanol solution of the DPPH of g/mL, concentration are the FeSO that the salicylic ethanol solution of 10mmol/L, concentration are 10mmol/L
4the H that aqueous solution, concentration are 8.8mmol/L
2o
2the pyrogallol solution that the HCl solution that the Tris-HCl buffer solution that aqueous solution, pH are 8.2, concentration are 10mmol/L, concentration are 5mmol/L (the HCl solution that the concentration of take is 10mmol/L is solvent).
(1) the suppression ratio test to DPPH free radical
Pipette testing sample solution 3mL in 10mL volumetric flask, adding subsequently 3mL concentration is 2 * 10
-4g/mL DPPH solution.Cover stopper, shake up, reaction 30min, measures absorbance A at 517nm place
i; Measure the absorbance A of 3mL sample liquid and 3mL alcohol mixeding liquid
j; Measuring 3mL concentration is 2 * 10
-4g/mLDPPH solution and the mixed absorbance A of 3mL pure water
0.According to formula P=[1-(A
i-A
j)/A
0] * 100%, brings the absorbance recording to try to achieve the suppression ratio of liquid to be measured to DPPH free radical into.
(2) the suppression ratio test to OH free radical
In the volumetric flask of 10mL, add the salicylic acid solution of 10mmol/L and the FeSO of 10mmol/L
4each 2mL of solution, then adds liquid 2mL to be measured, then to add 2mL concentration be the H of 8.8mmol/L
2o
2solution reacts 30min after shaking up in 37 ℃ of water-baths.At 510nm place, measure absorbance A
i; With 2mL pure water, replace H
2o
2measure absorbance A
j; With 2mL pure water, replace liquid to be measured to measure absorbance A
0.According to formula P=[1-(A
i-A
j)/A
0] * 100%, brings the absorbance recording to try to achieve the suppression ratio of liquid to be measured to OH free radical into.
(3) to O
2 -the suppression ratio test of free radical
Get pH and be 8.2 Tris-HCl buffer solution 5mL in 10mL volumetric flask, preheating 20min in 25 ℃ of water-baths, then adds the pyrogallol solution 0.5mL of liquid 2mL to be measured and 5mmol/L successively, shakes up immediately, in 25 ℃ of water-baths, react 4min, at 320nm place, measure immediately its absorbance A
i; HCl solution 0.5mL with 10mmol/L replaces pyrogallol, measures absorbance A
j; With 2mL pure water, replace liquid to be measured to measure absorbance A
0.According to formula P=[1-(A
i-A
j)/A
0] * 100%, brings the absorbance recording to try to achieve liquid to be measured to O into
2 -the suppression ratio of free radical.
Hydroscopicity test
Take eye cream sample 5g and be placed in weighing botle, at (20 ± 1) ℃, relative humidity, in 43%, 75% environment, place, every 1h, take out and weigh once, to 8h.By following formula, calculate hydroscopicity.
M wherein
nfor placing sample quality after n hour, g; m
0for placing front testing sample quality, g.
Organoleptic properties evaluation
Whether the eye cream of preparing visual observations mastic under room temperature and non-direct sunlight is fine and smooth, and whether color and luster uniformity, with olfactory sensation, differentiates that whether abnormal smells from the patient is pure.
PH test
Take sample 3.0g, put into and fill 30.0mL and remove CO
2the small beaker of deionized water in, be heated to 40 ± 1 ℃ and constantly stir, be chilled to after room temperature with the pH meter measurement of having proofreaied and correct.
High and low temperature experiment
Sample is packed in sealed plastic box, be placed in respectively the constant temperature oven of 40 ℃ and the freezer compartment of refrigerator 24h of-10 ℃, taking-up observes whether have oil-water separation phenomenon or obvious character difference after returning to room temperature.
Efficacy test
Select 20 people as tester, the mean age was 35 one full year of life, mostly was dry hydropenia skin quality.After subject is early later than clean every day, smear near the eyes eye cream, using altogether 90 days, every 15 days, with skinanalysis apparatus, testing a skin.And to several experimenters wherein before using eye cream and use the eye after 15 minutes and 30 minutes to take pictures.
Test result
Emulsified particles test result
As can be seen from Figure 1, the granule of this eye cream sample is little and be uniformly dispersed, and emulsify well is described.Conventionally under the fixing prerequisite of emulsifying agent, when adjusting glycerol, butanediol, pentanediol ratio and being 4:2:1, the eye cream decentralized photo granularity of preparing is the most even, and mastic is the finest and the smoothest.
Antioxidation test result
The suppression ratio of table 2 eye cream solution to 3 kinds of free radicals
| Free radical | DPPH· | ·OH | ·O 2 - |
| Suppression ratio | 84.9% | 63.6% | 53.6% |
Table 2 is the suppression ratio of eye cream solution to 3 kinds of free radicals.Can find out that in concentration be 5.00 * 10
-3during g/mL, eye cream solution is to DPPH, OH and O
2 -3the suppression ratio of planting free radical has reached respectively 84.9%, 63.6% and 53.6%, shows that eye cream of the present invention has stronger oxidation resistance, can effectively remove free radical.Stronger oxidation resistance is mainly by by composite acquisitions such as antioxidant network system and resveratrol, Olibanum extract, Radix Rhodiolae extracts.
Performance of keeping humidity is analyzed
Take the time as abscissa, hydroscopicity be vertical coordinate mapping, the time dependent graph of a relation of hydroscopicity of eye cream sample is shown in Fig. 2.In figure, can find out that hydroscopicity is negative value, illustrating that the long period is placed sample all can dehydration; But owing to having added multiple wetting agent in sample, at 20 ℃, relative humidity is respectively in 75% and 43% environment and places after 8h, and hydroscopicity is respectively-1.04% and-1.15%, and dehydration is very slow, illustrates that this eye cream has good moisture-retaining capacity.
Sense organ and physical and chemical testing result
Table 3 sense organ and physical and chemical index test result
The test result of table 3 shows the sense organ of eye cream of the present invention and the standard-required that physical and chemical index all meets China's cosmetic industry.
Result on trial is analyzed
Fig. 3 is to be that 55 years old, the trier of dry skin are before being used eye cream and use skin near the eyes after 15 minutes, the 30 minutes comparison diagram of taking pictures at an age.As can be seen from the figure, before use, skin lines is darker near the eyes, and wrinkle is obvious; Use eye cream of the present invention after 15 minutes, wrinkle obviously shoals, and experimenter can obviously feel that skin lifts sense; Use after 30 minutes, skin lines continues to shoal, and experimenter still can feel and lift effect.
The experimenter that Fig. 4 is respectively 42 years old and 26 years old, dry skin for two ages wherein before use with use comparison diagram of skin near the eyes after 90 days, its near the eyes skin indices situation of change in Table 4.Can find out, use continuously the near the eyes skin texture of this eye cream after 90 days obviously to shoal, the dim heavy problem of hydropenia and near the eyes skin makes moderate progress, and profile becomes and compacts near the eyes.
Table 4 is used before and after eye cream 90 days each index situation of change of skin near the eyes
Claims (3)
1. an eye cream, is characterized in that the formula of described eye cream is:
2. a preparation method for eye cream as claimed in claim 1, is characterized in that comprising the following steps:
A phase and B are placed in respectively to 70-75 ℃ of water-bath mutually and stir 25-30min, decorating film is dissolved, then the F having dissolved is added to A it is uniformly dispersed in mutually, then while stirring B is added to; After rapid stirring 25-30min, lower the temperature, while being cooled to 40-45 ℃, C phase, D phase and E added respectively mutually and be stirred to evenly, temperature stops while being down to 30-35 ℃ stirring, and discharging, obtains described eye cream.
3. the preparation method of a kind of eye cream according to claim 2, is characterized in that in preparation process, for making manufactured goods total amount remain 100g, adding appropriate distilled water when adding each phase again.
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705414A (en) * | 2013-12-12 | 2014-04-09 | 诺斯贝尔(中山)无纺日化有限公司 | Eye cream customized for Night Cats |
| CN104027269A (en) * | 2014-06-17 | 2014-09-10 | 娇时化妆品（杭州）有限公司 | Eye cream and preparation method thereof |
| CN104546543A (en) * | 2015-01-09 | 2015-04-29 | 杭州四林生物科技有限公司 | tea polyphenol containing anti-wrinkling and skin-moistening eye cream and preparation process thereof |
| CN104887617A (en) * | 2014-12-26 | 2015-09-09 | 尚臣美邦（北京）生物科技有限公司 | Composition for nursing eyes and preparation method of composition |
| CN105943475A (en) * | 2016-07-08 | 2016-09-21 | 广州花出见生物科技有限公司 | Wrinkle-relieving eye cream containing traditional Chinese medicine components as well as preparation method and application thereof |
| CN105997841A (en) * | 2016-08-08 | 2016-10-12 | 黄美风 | Beauty maintenance eye cream and preparation method thereof |
| CN106491460A (en) * | 2016-12-23 | 2017-03-15 | 广州市科能化妆品科研有限公司 | A kind of eye essence and preparation method thereof |
| CN107375145A (en) * | 2017-08-09 | 2017-11-24 | 广州丸美生物科技有限公司 | Cosmetic base, preparation method and applications and eye cream and preparation method thereof |
| CN107661262A (en) * | 2017-10-28 | 2018-02-06 | 安徽孔氏奇医药科技有限公司 | One kind is compacted radioresistance eye cream and preparation method thereof |
| CN110522713A (en) * | 2019-08-14 | 2019-12-03 | 天津科技大学 | One kind is crease-resistant to remove fat granule and black-eyed milk matrix lipid body eye cream and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078283A (en) * | 2011-01-25 | 2011-06-01 | 朱爱民 | Traditional Chinese medicinal nutritional emulsifiable paste for whitening skin and removing speckles |
-
2013
- 2013-11-12 CN CN201310561265.4A patent/CN103599062B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078283A (en) * | 2011-01-25 | 2011-06-01 | 朱爱民 | Traditional Chinese medicinal nutritional emulsifiable paste for whitening skin and removing speckles |
Non-Patent Citations (2)
| Title |
|---|
| SEPPIC: "SIMULGEL EG", 《安全技术说明书》 * |
| 丁克祥: "国际抗氧化网络理论在抗衰老化妆品研制中的应用", 《第十届东南亚地区医学美容学术大会论文汇编》 * |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103705414B (en) * | 2013-12-12 | 2016-01-20 | 诺斯贝尔化妆品股份有限公司 | A kind of eye cream |
| CN103705414A (en) * | 2013-12-12 | 2014-04-09 | 诺斯贝尔(中山)无纺日化有限公司 | Eye cream customized for Night Cats |
| CN104027269A (en) * | 2014-06-17 | 2014-09-10 | 娇时化妆品（杭州）有限公司 | Eye cream and preparation method thereof |
| CN104887617B (en) * | 2014-12-26 | 2017-11-14 | 尚臣美邦（北京）生物科技有限公司 | A kind of composition for eye-care and preparation method thereof |
| CN104887617A (en) * | 2014-12-26 | 2015-09-09 | 尚臣美邦（北京）生物科技有限公司 | Composition for nursing eyes and preparation method of composition |
| CN104546543A (en) * | 2015-01-09 | 2015-04-29 | 杭州四林生物科技有限公司 | tea polyphenol containing anti-wrinkling and skin-moistening eye cream and preparation process thereof |
| CN105943475A (en) * | 2016-07-08 | 2016-09-21 | 广州花出见生物科技有限公司 | Wrinkle-relieving eye cream containing traditional Chinese medicine components as well as preparation method and application thereof |
| CN105997841A (en) * | 2016-08-08 | 2016-10-12 | 黄美风 | Beauty maintenance eye cream and preparation method thereof |
| CN106491460A (en) * | 2016-12-23 | 2017-03-15 | 广州市科能化妆品科研有限公司 | A kind of eye essence and preparation method thereof |
| CN106491460B (en) * | 2016-12-23 | 2019-09-27 | 广州市科能化妆品科研有限公司 | A kind of eye essence and preparation method thereof |
| CN107375145A (en) * | 2017-08-09 | 2017-11-24 | 广州丸美生物科技有限公司 | Cosmetic base, preparation method and applications and eye cream and preparation method thereof |
| CN107661262A (en) * | 2017-10-28 | 2018-02-06 | 安徽孔氏奇医药科技有限公司 | One kind is compacted radioresistance eye cream and preparation method thereof |
| CN110522713A (en) * | 2019-08-14 | 2019-12-03 | 天津科技大学 | One kind is crease-resistant to remove fat granule and black-eyed milk matrix lipid body eye cream and preparation method thereof |
| CN110522713B (en) * | 2019-08-14 | 2022-04-12 | 天津科技大学 | Milk-based liposome eye cream capable of resisting wrinkles, removing fat particles and blacking eyes and preparation method thereof |
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| CN103599062B (en) | 2016-05-25 |
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Address after: 237009 Anhui Lu'an Economic Development Zone Science and Technology Innovation Service Center Co-patentee after: ANHUI University Patentee after: Anhui Dan Dan materia medica Technology Co.,Ltd. Address before: 237009 Anhui Lu'an Economic Development Zone Science and Technology Innovation Service Center Co-patentee before: Anhui University Patentee before: LU'AN DANHUANG BIOTECHNOLOGY Co.,Ltd. |
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Effective date of registration: 20230821 Address after: No. 716, 7th floor, building 4, No. 99, Guangfu Road, Wuhou District, Chengdu, Sichuan 610041 Patentee after: Chengdu yishenrui Technology Co.,Ltd. Address before: 237009 Anhui Lu'an Economic Development Zone Science and Technology Innovation Service Center Patentee before: Anhui Dan Dan materia medica Technology Co.,Ltd. Patentee before: ANHUI University Effective date of registration: 20230821 Address after: Room 1103, Unit 2, Building 7, Xiangyi Huafu, Huajian Road, Zhanggong District, Ganzhou, Jiangxi Province 341000 Patentee after: Zhao Xianliang Address before: No. 716, 7th floor, building 4, No. 99, Guangfu Road, Wuhou District, Chengdu, Sichuan 610041 Patentee before: Chengdu yishenrui Technology Co.,Ltd. |