CN105943475A - Wrinkle-relieving eye cream containing traditional Chinese medicine components as well as preparation method and application thereof - Google Patents
Wrinkle-relieving eye cream containing traditional Chinese medicine components as well as preparation method and application thereof Download PDFInfo
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- CN105943475A CN105943475A CN201610541050.XA CN201610541050A CN105943475A CN 105943475 A CN105943475 A CN 105943475A CN 201610541050 A CN201610541050 A CN 201610541050A CN 105943475 A CN105943475 A CN 105943475A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a wrinkle-relieving eye cream containing traditional Chinese medicine components as well as a preparation method and application thereof. The wrinkle-relieving eye cream is prepared from the following raw materials in parts by weight: 50-60 parts of water, 2.0-4.0 parts of glycerol, 0.5-0.8 part of methyl glucoside eicoepoxyethane, 0.2-0.6 part of stearic acid, 0.1-0.3 part of cyclopentasiloxane, 0.02-0.04 part of hyaluronic acid, 0.3-0.8 part of isomerized sugar, 0.02-0.05 part of rose essential oil, 0.05-0.1 part of radix astragali extractive, 0.05-0.1 part of eleutherococcus extractive, 0.05-0.1 part of rhodiola rosea extractive, 0.05-0.1 part of fiveleaf gynostemma herb extractive and 0.05-0.1 part of radix lithospermi extractive. The wrinkle-relieving eye cream is refreshing, smooth, mild and irritation-free, and is capable of retaining moisture of eye skin for a long time, accelerating eye blood circulation and effectively reducing eye fine wrinkles; the main additives of the wrinkle-relieving eye cream are natural plants, so that the wrinkle-relieving eye cream is green, safe and environmental-friendly.
Description
Technical field
The present invention relates to cosmetic skin care field, particularly relate to a kind of anti-wrinkle eye cream containing Chinese medicine ingredients and preparation method thereof and answer
With.
Background technology
Eye skin is the thinnest skin of human body, is again movable most frequent position simultaneously, but also is to pull skin in cosmetic
The most places of number, are very easy to grow wrinkle, and once grow and be difficult to eliminate.The work of high rhythm and life so that
Stay up late, working overtime becomes the life normality of a lot of people, this to cause eyestrain, deepen eyeprint, accelerate eye muscle aging play
The effect added fuel to the flames, especially for women, the maintenance of eye skin is particularly important.Currently there are most
Eyeware products and solution for lenses and contact lenses is exactly eye cream, but most of eye cream is all to be synthesized by industrial chemicals, and itself just has certain for skin
Poison, for these reasons, develop a natural drug anti-wrinkle eye cream containing medicinal herb components to overcome a difficult problem for prior art,
Become particularly important.
Summary of the invention
It is an object of the invention to overcome weak point of the prior art, it is provided that a kind of anti-wrinkle eye cream containing Chinese medicine ingredients and
Its preparation method and application, described anti-wrinkle eye cream gentleness is non-stimulated, can effectively reduce eye wrinkle-removing, delay eye part skin old and feeble.
For achieving the above object, the application provides following technical scheme:
First aspect, the invention provides a kind of anti-wrinkle eye cream containing Chinese medicine ingredients, the described crease-resistant eye containing Chinese medicine ingredients
The raw material of frost, counts by weight, including: water 50-60 part, glycerol 2.0-4.0 part, methylglucoside 20 oxirane
0.5-0.8 part, stearic acid 0.2-0.6 part, siliceous smooth dose of 0.1-0.3 part, hyaluronic acid 0.02-0.04 part, isomerized sugar 0.3-0.8
Part, Flos Rosae Rugosae quintessence oil 0.02-0.05 part, Radix Astragali extract 0.05-0.1 part, cortex acanthopanacis radicis extract 0.05-0.1 part, Radix Rhodiolae extract
Thing 0.05-0.1 part, Herb Gynostemmae Pentaphylli extract 0.05-0.1 part, radix lithospermi extract 0.05-0.1 part.
Preferably, the described anti-wrinkle eye cream containing Chinese medicine ingredients, the raw material of the described anti-wrinkle eye cream containing Chinese medicine ingredients, press
Parts by weight meter, including: water 50-55 part, glycerol 2.2-3.8 part, methylglucoside 20 oxirane 0.6-0.7 part, hard
Fat acid 0.3-0.5 part, siliceous smooth dose of 0.15-0.25 part, hyaluronic acid 0.03-0.04 part, isomerized sugar 0.4-0.7 part, rhodamine toner
Oil 0.02-0.04 part, Radix Astragali extract 0.07-0.1 part, cortex acanthopanacis radicis extract 0.07-0.1 part, Radix Rhodiolae extract 0.07-0.1
Part, Herb Gynostemmae Pentaphylli extract 0.07-0.1 part, radix lithospermi extract 0.07-0.1 part.
It is further preferred that the described anti-wrinkle eye cream containing Chinese medicine ingredients, the described anti-wrinkle eye cream containing Chinese medicine ingredients former
Material, counts by weight, including: 55 parts of water, glycerol 3.5 parts, 0.6 part of methylglucoside 20 oxirane, tristearin
Acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, isomerized sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04 part, the Radix Astragali carry
Take thing 0.1 part, cortex acanthopanacis radicis extract 0.1 part, Radix Rhodiolae extract 0.1 part, Herb Gynostemmae Pentaphylli extract 0.1 part, radix lithospermi extraction
Thing 0.1 part.
Preferably, described containing in the raw material of the anti-wrinkle eye cream of Chinese medicine ingredients, described water is deionized water.
It is understood that it is described containing in the raw material of the anti-wrinkle eye cream of Chinese medicine ingredients, to described Radix Astragali extract, Radix Acanthopanacis Senticosi
Extract, Radix Rhodiolae extract, Herb Gynostemmae Pentaphylli extract, the preparation method of radix lithospermi extract do not have special restriction, can adopt
Prepared described Radix Astragali extract, cortex acanthopanacis radicis extract, Radix Rhodiolae extract, strand is extracted through Chinese medicine general extraction methods with crude drug
Stock blue extract, the method for radix lithospermi extract.
Preferably, described Chinese medicine general extraction methods, comprise the steps:
According to the ratio that w/v mg/ml is 1:10～20 of described crude drug Yu solvent, crude drug and solvent are mixed
After under conditions of 60-100 DEG C stir 2～4h (preferably 3h), be collected by filtration and obtain the first filtrate and the first filtering residue；According to institute
State the ratio that w/v mg/ml is 1:10～20 of the first filtering residue and solvent, after described first filtering residue and solvent are mixed
Stir 1～3h (preferably 2h) under conditions of 60-100 DEG C, be collected by filtration and obtain the second filtrate and the second filtering residue, by described first
After filtrate and described second filtrate mixing, concentrating under reduced pressure prepares Chinese medicine extract.
It is further preferred that in the preparation method of described Chinese medicine extract, described solvent includes water and/or ethanol.
It is further preferred that in the preparation method of described Chinese medicine extract, described crude drug is for being dried raw material of Chinese medicine, pulverizing
Prepare.
It is further preferred that in the preparation method of described Chinese medicine extract, the size of described crude drug is 50-400 mesh.
Second aspect, the invention provides the preparation method of a kind of anti-wrinkle eye cream containing Chinese medicine ingredients, comprises the following steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: water 50-60 part, glycerol 2.0-4.0 part, methyl glucose
Glucoside 20 oxirane 0.5-0.8 part, stearic acid 0.2-0.6 part, siliceous smooth dose of 0.1-0.3 part, hyaluronic acid 0.02-0.04
Part, isomerized sugar 0.3-0.8 part, Flos Rosae Rugosae quintessence oil 0.02-0.05 part, Radix Astragali extract 0.05-0.1 part, cortex acanthopanacis radicis extract 0.05-0.1
Part, Radix Rhodiolae extract 0.05-0.1 part, Herb Gynostemmae Pentaphylli extract 0.05-0.1 part, radix lithospermi extract 0.05-0.1 part；By glycerol,
Methylglucoside 20 oxirane, stearic acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose with account for described water gross weight 1/4～2/3
Water (water of the 1/2 of the most described water gross weight) mixing after, under the rotating speed of 150-200r/min stir 10-15min obtain
Mixture, then hyaluronic acid, isomerized sugar, Radix Astragali extract, cortex acanthopanacis radicis extract, Radix Rhodiolae extract, Herb Gynostemmae Pentaphylli are extracted
Thing, radix lithospermi extract add in described mixture after mixing with excess water, and stir under the rotating speed of 150-200r/min
20-25min, sterilizing, encapsulation prepare the anti-wrinkle eye cream containing Chinese medicine ingredients.
Preferably, described containing in the preparation method of the anti-wrinkle eye cream of Chinese medicine ingredients, the described crease-resistant eye containing Chinese medicine ingredients
The raw material of frost, counts by weight, including: water 50-55 part, glycerol 2.2-3.8 part, methylglucoside 20 oxirane
0.6-0.7 part, stearic acid 0.3-0.5 part, siliceous smooth dose of 0.15-0.25 part, hyaluronic acid 0.03-0.04 part, isomerized sugar 0.4-0.7
Part, Flos Rosae Rugosae quintessence oil 0.02-0.04 part, Radix Astragali extract 0.07-0.1 part, cortex acanthopanacis radicis extract 0.07-0.1 part, Radix Rhodiolae extract
Thing 0.07-0.1 part, Herb Gynostemmae Pentaphylli extract 0.07-0.1 part, radix lithospermi extract 0.07-0.1 part.
It is further preferred that described containing in the preparation method of the anti-wrinkle eye cream of Chinese medicine ingredients, described containing Chinese medicine ingredients
The raw material of anti-wrinkle eye cream, counts by weight, including: 55 parts of water, glycerol 3.5 parts, methylglucoside 20 oxirane
0.6 part, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, isomerized sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04
Part, Radix Astragali extract 0.1 part, cortex acanthopanacis radicis extract 0.1 part, Radix Rhodiolae extract 0.1 part, Herb Gynostemmae Pentaphylli extract 0.1 part,
Radix lithospermi extract 0.1 part.
It is understood that it is described containing in the raw material of the anti-wrinkle eye cream of Chinese medicine ingredients, to described Radix Astragali extract, Radix Acanthopanacis Senticosi
Extract, Radix Rhodiolae extract, Herb Gynostemmae Pentaphylli extract, the preparation method of radix lithospermi extract do not have special restriction, can adopt
Prepared described Radix Astragali extract, cortex acanthopanacis radicis extract, Radix Rhodiolae extract, strand is extracted through Chinese medicine general extraction methods with crude drug
Stock blue extract, the method for radix lithospermi extract.
Preferably, described Chinese medicine general extraction methods, comprise the steps:
According to the ratio that w/v mg/ml is 1:10～20 of described crude drug Yu solvent, crude drug and solvent are mixed
After under conditions of 60-100 DEG C stir 2～4h (preferably 3h), be collected by filtration and obtain the first filtrate and the first filtering residue；According to institute
State the ratio that w/v mg/ml is 1:10～20 of the first filtering residue and solvent, after described first filtering residue and solvent are mixed
Stir 1～3h (preferably 2h) under conditions of 60-100 DEG C, be collected by filtration and obtain the second filtrate and the second filtering residue, by described first
After filtrate and described second filtrate mixing, concentrating under reduced pressure prepares Chinese medicine extract.
It is further preferred that in the preparation method of described Chinese medicine extract, described solvent includes water and/or ethanol.
It is further preferred that in the preparation method of described Chinese medicine extract, described crude drug is for being dried raw material of Chinese medicine, pulverizing
Prepare.
It is further preferred that in the preparation method of described Chinese medicine extract, the size of described crude drug is 50-400 mesh.
The third aspect, the invention provides a kind of anti-wrinkle eye cream containing Chinese medicine ingredients as described in relation to the first aspect at cosmetic skin care
Application in terms of product.
Fourth aspect, the invention provides the preparation method of a kind of anti-wrinkle eye cream containing Chinese medicine ingredients as described in second aspect
Application in terms of preparing cosmetic skin care product.
In anti-wrinkle eye cream of the present invention, each Chinese herbal medicine extract has following effect and a feature:
The Radix Astragali, has another name called continuous stilbene.Herbaceos perennial, the most more than 2000 year medicinal history, it has enhancing body to exempt from
Epidemic disease function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial action.Modern study finds, the Radix Astragali is not
It is only capable of coronary artery dilator, improves blood supply of cardiac muscle, improve immunologic function, and can the process of delaying cell aging.
Radix Et Caulis Acanthopanacis Senticosi is the most i.e. considered to have and adds essence and mend marrow and the good medicine of anti-aging effects.Trade name Radix Acanthopanacis Senticosi, former main product in
Mountain area, Heilongjiang Province, local popular name is practised and is claimed " tiger is hasty and careless ".Prove through modern medicine, Radix Et Caulis Acanthopanacis Senticosi have expansion blood vessel, reduce blood pressure,
Anti-platelet aggregation, maintenance blood pressure are steady, improve hemorheological characteristics and improve microcirculatory effect.
Radix Rhodiolae is the herb of crassulaceae plants full lobe Radix Rhodiolae, can make medicinal, it is possible to QI invigorating lung heat clearing, and Fructus Alpiniae Oxyphyllae is nourished heart.Modern
Pharmacology and clinical research find, Radix Rhodiolae has the benefiting action of similar Radix Ginseng, can anti-hypoxia, cold resistance, resisting fatigue, radioprotective,
Delay body aging also to have the biggest cosmetic result, skin care item can be made, it is possible to be edible.
Herb Gynostemmae Pentaphylli is the herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli, and modern medicine finds have Multiple components and part Radix Ginseng in its composition
Saponin structure is identical, has defying age, resisting fatigue, anticancer, endocrine regulation function, can improve human body adaptability to changes and immunity
Power, reduces cholesterol and transaminase, prophylaxis of tumours, suppresses ulcer, keeping tensions down, calm, analgesia.
Radix lithospermi contains multiple polysaccharide, saponarin and extraordinary Trace Elements, has good crease-resistant, moisturizing, antioxidation,
The multiple effects such as delay skin aging, reparation Skin Cell, promotion Skin Cell regenerate, dissolve, the row's of forcing skin foreign body.Skin
Long-term absorption radix lithospermi element composition, can improve skin elasticity, makes skin become pure white smooth, and has suppression tyrosinase activity
Effect, thus melanic generation can be suppressed, treating for skin disease function well pigmentosa to chloasma, freckle etc..
Beneficial effects of the present invention is as follows: the anti-wrinkle eye cream containing Chinese medicine ingredients provided by the present invention, the most soft and smooth, gentle
Non-stimulated, the moisture of eye skin can be maintained for a long time, promote ocular circulation, effective eye reduces the generation of microgroove, main
Want additive to be all from natural plants, there is green, the feature such as safe and environment-friendly.
Accompanying drawing explanation
In order to be illustrated more clearly that the embodiment of the present application or technical scheme of the prior art, below will be to embodiment or existing skill
In art description, the required accompanying drawing used is briefly described, it should be apparent that, the accompanying drawing in describing below is only the application's
Some embodiments, for those of ordinary skill in the art, on the premise of not paying creative work, it is also possible to according to this
A little accompanying drawings obtain other accompanying drawing.
Different types of eye cream that uses that Fig. 1 provides for the embodiment of the present invention affects schematic diagram to skin elasticity.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with in the embodiment of the present invention
Accompanying drawing, is clearly and completely described the technical scheme in the embodiment of the present invention, it is clear that described embodiment is this
Bright a part of embodiment rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art are not having
There is on the premise of making creative work the every other embodiment obtained, broadly fall into the scope of protection of the invention.
Radix Astragali extract that the embodiment of the present invention is provided, cortex acanthopanacis radicis extract, Radix Rhodiolae extract, Herb Gynostemmae Pentaphylli extract,
Radix lithospermi extract part all uses crude drug to extract through Chinese medicine general extraction methods and prepares, described Chinese medicine general extraction methods
Comprise the steps:
According to the ratio that w/v mg/ml is 1:20 of described crude drug Yu water, after crude drug and solvent are mixed
Stir 3h under conditions of 100 DEG C, be collected by filtration and obtain the first filtrate and the first filtering residue；Weight according to described first filtering residue Yu solvent
Amount volume ratio mg/ml is the ratio of 10, stirs 2h, filter and receive after described first filtering residue and water being mixed under conditions of 80 DEG C
Collection obtains the second filtrate and the second filtering residue, and concentrating under reduced pressure after described first filtrate and described second filtrate mixing is prepared Chinese medicine extraction
Thing.
Embodiment 1
Embodiments provide the preparation method of a kind of anti-wrinkle eye cream containing Chinese medicine ingredients, comprise the steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: deionized water 50 parts, glycerol 2.2 parts,
0.6 part of methylglucoside 20 oxirane, stearic acid 0.3 part, siliceous smooth dose 0.15 part, hyaluronic acid 0.03 part,
Isomerized sugar 0.4 part, Flos Rosae Rugosae quintessence oil 0.02 part, Radix Astragali extract 0.07 part, cortex acanthopanacis radicis extract 0.07 part, Radix Rhodiolae extract
0.07 part, Herb Gynostemmae Pentaphylli extract 0.07 part, radix lithospermi extract 0.07 part；
By glycerol, methylglucoside 20 oxirane, stearic acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose with account for described in go from
The deionized water mixing of the 1/2 of 55.1 parts of sub-water adds in reaction pot, stirs 10min under the rotating speed of 150r/min, then will thoroughly
Bright matter acid, isomerized sugar, Chinese herbal medicine extract mixing add balance deionized water, add in the lump in reaction pot after agitation as appropriate,
Stirring 20min under the rotating speed of 150r/min, be then charged in the bottle of sterilization, sealing i.e. obtains anti-wrinkle eye cream one.
Embodiment 2
Embodiments provide the preparation method of a kind of anti-wrinkle eye cream containing Chinese medicine ingredients, comprise the steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: deionized water 55 parts, glycerol 3.8 parts,
0.7 part of methylglucoside 20 oxirane, stearic acid 0.5 part, siliceous smooth dose 0.25 part, hyaluronic acid 0.04 part,
Isomerized sugar 0.7 part, Flos Rosae Rugosae quintessence oil 0.04 part, Radix Astragali extract 0.1 part, cortex acanthopanacis radicis extract 0.1 part, Radix Rhodiolae extract
0.1 part, Herb Gynostemmae Pentaphylli extract 0.1 part, radix lithospermi extract 0.1 part；
By account for described deionized water 55.1 parts 1/2 deionized water, glycerol, methylglucoside 20 oxirane, hard
Fat acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose of mixing add in reaction pot, stir 15min under the rotating speed of 200r/min, then will thoroughly
Bright matter acid, isomerized sugar, Chinese herbal medicine extract mixing add balance deionized water, add in the lump in reaction pot after agitation as appropriate,
Stirring 25min under the rotating speed of 200r/min, be then charged in the bottle of sterilization, sealing i.e. obtains anti-wrinkle eye cream two.
Embodiment 3
Embodiments provide the preparation method of a kind of anti-wrinkle eye cream containing Chinese medicine ingredients, comprise the steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: deionized water 55 parts, glycerol 3.5 parts,
0.6 part of methylglucoside 20 oxirane, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, different
Structure sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04 part, Radix Astragali extract 0.1 part, cortex acanthopanacis radicis extract 0.1 part, Radix Rhodiolae extract 0.1
Part, Herb Gynostemmae Pentaphylli extract 0.1 part, radix lithospermi extract 0.1 part；
By account for described deionized water 55.1 parts 1/2 deionized water, glycerol, methylglucoside 20 oxirane, hard
Fat acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose of mixing add in reaction pot, stir 15min under the rotating speed of 180r/min, then will thoroughly
Bright matter acid, isomerized sugar, Chinese herbal medicine extract mixing add balance deionized water, add in the lump in reaction pot after agitation as appropriate,
Stirring 25min under the rotating speed of 180r/min, be then charged in the bottle of sterilization, sealing i.e. obtains anti-wrinkle eye cream three.
Comparative example 1 is without Radix Acanthopanacis Senticosi, the anti-wrinkle eye cream of Herb Gynostemmae Pentaphylli
Embodiments provide a kind of without Radix Acanthopanacis Senticosi, the preparation method of the anti-wrinkle eye cream of Herb Gynostemmae Pentaphylli composition, including as follows
Step:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: deionized water 55.1 parts, glycerol 3.5 parts,
0.6 part of methylglucoside 20 oxirane, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, different
Structure sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04 part, Radix Astragali extract 0.1 part, Radix Rhodiolae extract 0.1 part, radix lithospermi extract 0.1
Part；
By account for described deionized water 55.1 parts 1/2 deionized water, glycerol, methylglucoside 20 oxirane, hard
Fat acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose of mixing add in reaction pot, stir 15min under the rotating speed of 180r/min, then will thoroughly
Bright matter acid, isomerized sugar, Chinese herbal medicine extract mixing add balance deionized water, add in the lump in reaction pot after agitation as appropriate,
Stirring 25min under the rotating speed of 180r/min, be then charged in the bottle of sterilization, sealing i.e. obtains anti-wrinkle eye cream four.
Comparative example 2 is without Radix Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, the anti-wrinkle eye cream of radix lithospermi
Embodiments provide a kind of without Radix Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, the preparation method of anti-wrinkle eye cream of radix lithospermi composition,
Comprise the steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: deionized water 55.1 parts, glycerol 3.5 parts,
0.6 part of methylglucoside 20 oxirane, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, different
Structure sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04 part, Radix Astragali extract 0.1 part, Radix Rhodiolae extract 0.1 part；
By account for described deionized water 55.1 parts 1/2 deionized water, glycerol, methylglucoside 20 oxirane, hard
Fat acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose of mixing add in reaction pot, stir 15min under the rotating speed of 180r/min, then will thoroughly
Bright matter acid, isomerized sugar, Chinese herbal medicine extract mixing add balance deionized water, add in the lump in reaction pot after agitation as appropriate,
Stirring 25min under the rotating speed of 180r/min, be then charged in the bottle of sterilization, sealing i.e. obtains anti-wrinkle eye cream five.
Comparative example 3 is containing Galla Chinensis, Radix Angelicae Sinensis, the anti-wrinkle eye cream of Semen Coicis
Embodiments provide a kind of containing Galla Chinensis, Radix Angelicae Sinensis, the preparation method of anti-wrinkle eye cream of Semen Coicis composition, bag
Include following steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: deionized water 55.1 parts, glycerol 3.5 parts,
0.6 part of methylglucoside 20 oxirane, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, different
Structure sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04 part, Radix Astragali extract 0.1 part, Galla Chinensis extract 0.1 part, Radix Rhodiolae extract 0.1
Part, Radix Angelicae Sinensis extract 0.1 part, Semen Coicis extract 0.1 part；
By account for described deionized water 55.1 parts 1/2 deionized water, glycerol, methylglucoside 20 oxirane, hard
Fat acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose of mixing add in reaction pot, stir 15min under the rotating speed of 180r/min, then will thoroughly
Bright matter acid, isomerized sugar, Chinese herbal medicine extract mixing add balance deionized water, add in the lump in reaction pot after agitation as appropriate,
Stirring 25min under the rotating speed of 180r/min, be then charged in the bottle of sterilization, sealing i.e. obtains anti-wrinkle eye cream six.
The crease-resistant efficacy assessments of effect example 1 different ratio eye cream
This test uses skin elasticity test to evaluate crease-resistant effect, uses CK company of Germany skin elasticity tester
MPA580, uses suction method, eye cream, comparative example 1～3 institute to embodiment 1～3 gained respectively with constant negative pressure pattern
Eye cream and commercially available Buddhist clean poem orange perfume (or spice) compact anti-wrinkle eye cream carry out anti-wrinkle effect test, i.e. test probe skin surface apply
Skin is sucked probe aperture by negative pressure, and after negative pressure disappears, skin deformation is recovered, and skin deformation changed with negative pressure and time can be by test
Launching light in instrument and the device accepting light records, this device can reflect that skin is inhaled into the degree of depth, so available skin stretch length
Time history plot, represents skin maximum tension amount with Uf, and Ue represents that constant negative pressure is added to skin during skin upper 0.1 second
The amount of tension of skin, Ur indicates that Ua represents that cancellation negative pressure arrives without skin amount of recovery after negative pressure 0.1S, Ur=Uf-Ue viscoelasticity part
Next time, follow-on test added the amount of recovery of negative pressure skin again, and R2=Ua/Uf, R2 are the parameter of a reflection skin elasticity, R2 value
The biggest then skin elasticity is the best, the best closer to 1 elasticity；
Test number: 35 people, is divided into 4 groups, often organizes 5 people,
Test period: 28 days,
Test index: skin elasticity
Test method: before smearing sample, experimenter uses clean water face, marks at canthus, experimenter left and right
1×1cm2The square Experimental Area of size, using left eye as the test zone of embodiment eye cream, it is right that the corresponding region of right eye is carried out
The test of ratio (the common eye cream in market), takes eye cream 0.1g and is applied to experimenter canthus, and using frequency is that the morning and evening is each the most once, continuously
Every day uses, it is to avoid atmospheric exposure.
Each test position elasticity R2 value is detected respectively at these position skinanalysis apparatus after 7d, 14d, 21d, 28d,
Each test zone respectively detects 5 hypoelasticity R2The meansigma methods of value.
After 20 experimenters use comparative example and embodiment 28d, measured at experimenter's labelling point by skin elasticity tester
After using 7,14,21, the skin elasticity of 28d changes as shown in Figure 1.
Interpretation: Fig. 1 is that the impact of skin elasticity is illustrated by different types of eye cream that the embodiment of the present invention provides
Figure；Compacted by the eye cream used obtained by embodiment 1～3, eye cream obtained by comparative example 1～3 and commercially available Buddhist clean poem orange perfume (or spice)
The variation tendency of the eye part skin elastic effect of the experimenter of anti-wrinkle eye cream understands, and uses eye cream obtained by embodiment 1～3, right
Raising is all presented than the compact skin elasticity of experimenter of anti-wrinkle eye cream of the eye cream obtained by embodiment 1～3 and commercially available Buddhist clean poem orange perfume (or spice)
Trend, wherein, use the eye of the experimenter of the eye cream obtained by embodiment 1～3 and the eye cream obtained by comparative example 1～3
Portion's skin elasticity effect all significantly better than using commercially available Buddhist clean poem orange perfume (or spice) to compact the experimenter of anti-wrinkle eye cream, wherein, uses embodiment
The using effect of the experimenter of the eye cream obtained by 1～3 is best, illustrates that its anti-wrinkle effect is best, Radix Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli are also described
With radix lithospermi, there is different effective ingredient, there is complementary collaborative potentiation.
Last it is noted that various embodiments above is only in order to illustrate technical scheme, it is not intended to limit；Although
With reference to foregoing embodiments, the present invention is described in detail, it will be understood by those within the art that: it still may be used
So that the technical scheme described in foregoing embodiments is modified, or the most some or all of technical characteristic is equal to
Replace；And these amendments or replacement, do not make the essence of appropriate technical solution depart from the model of various embodiments of the present invention technical scheme
Enclose.
Claims (10)
1. the anti-wrinkle eye cream containing Chinese medicine ingredients, it is characterised in that the raw material of the described anti-wrinkle eye cream containing Chinese medicine ingredients,
Count by weight, including: water 50-60 part, glycerol 2.0-4.0 part, methylglucoside 20 oxirane 0.5-0.8 part,
Stearic acid 0.2-0.6 part, siliceous smooth dose of 0.1-0.3 part, hyaluronic acid 0.02-0.04 part, isomerized sugar 0.3-0.8 part, rhodamine toner
Oil 0.02-0.05 part, Radix Astragali extract 0.05-0.1 part, cortex acanthopanacis radicis extract 0.05-0.1 part, Radix Rhodiolae extract 0.05-0.1
Part, Herb Gynostemmae Pentaphylli extract 0.05-0.1 part, radix lithospermi extract 0.05-0.1 part.
2. the anti-wrinkle eye cream containing Chinese medicine ingredients as claimed in claim 1, it is characterised in that described resisting containing Chinese medicine ingredients
The raw material of wrinkle eye cream, counts by weight, including: water 50-55 part, glycerol 2.2-3.8 part, methylglucoside 20 epoxy
Ethane 0.6-0.7 part, stearic acid 0.3-0.5 part, siliceous smooth dose of 0.15-0.25 part, hyaluronic acid 0.03-0.04 part, isomerized sugar
0.4-0.7 part, Flos Rosae Rugosae quintessence oil 0.02-0.04 part, Radix Astragali extract 0.07-0.1 part, cortex acanthopanacis radicis extract 0.07-0.1 part, red scape
It extract 0.07-0.1 part, Herb Gynostemmae Pentaphylli extract 0.07-0.1 part, radix lithospermi extract 0.07-0.1 part.
3. the anti-wrinkle eye cream containing Chinese medicine ingredients as claimed in claim 1, it is characterised in that described resisting containing Chinese medicine ingredients
The raw material of wrinkle eye cream, counts by weight, including: 55 parts of water, glycerol 3.5 parts, methylglucoside 20 oxirane 0.6
Part, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, isomerized sugar 0.6 part, Flos Rosae Rugosae quintessence oil 0.04 part,
Radix Astragali extract 0.1 part, cortex acanthopanacis radicis extract 0.1 part, Radix Rhodiolae extract 0.1 part, Herb Gynostemmae Pentaphylli extract 0.1 part, purple stamen
Grass extract 0.1 part.
4. the preparation method of the anti-wrinkle eye cream containing Chinese medicine ingredients, it is characterised in that comprise the following steps:
Take the raw material of the anti-wrinkle eye cream containing Chinese medicine ingredients of following portions by weight: water 50-60 part, glycerol 2.0-4.0 part, methyl
Glycoside 20 oxirane 0.5-0.8 part, stearic acid 0.2-0.6 part, siliceous smooth dose of 0.1-0.3 part, hyaluronic acid 0.02-0.04
Part, isomerized sugar 0.3-0.8 part, Flos Rosae Rugosae quintessence oil 0.02-0.05 part, Radix Astragali extract 0.05-0.1 part, cortex acanthopanacis radicis extract 0.05-0.1
Part, Radix Rhodiolae extract 0.05-0.1 part, Herb Gynostemmae Pentaphylli extract 0.05-0.1 part, radix lithospermi extract 0.05-0.1 part；By glycerol,
Methylglucoside 20 oxirane, stearic acid, Flos Rosae Rugosae quintessence oil, siliceous smooth dose with account for described water gross weight 1/4～2/3
Water mixing after, under the rotating speed of 150-200r/min, stir 10-15min obtain mixture, then by hyaluronic acid, isomerized sugar,
After Radix Astragali extract, cortex acanthopanacis radicis extract, Radix Rhodiolae extract, Herb Gynostemmae Pentaphylli extract, radix lithospermi extract mix with excess water
In mixture described in addition, and stirring 20-25min under the rotating speed of 150-200r/min, sterilizing, encapsulation prepare containing Chinese medicine
The anti-wrinkle eye cream of composition.
5. contain the anti-wrinkle eye cream of Chinese medicine ingredients as claimed in claim 1 or as claimed in claim 4 containing Chinese medicine ingredients
The preparation method of anti-wrinkle eye cream, it is characterised in that described containing in the raw material of the anti-wrinkle eye cream of Chinese medicine ingredients, carries the described Radix Astragali
Take thing, cortex acanthopanacis radicis extract, Radix Rhodiolae extract, Herb Gynostemmae Pentaphylli extract, radix lithospermi extract for using crude drug normal through Chinese medicine
Rule extracting method extracts and prepares, and described Chinese medicine general extraction methods comprises the steps:
According to the ratio that w/v mg/ml is 1:10～20 of described crude drug Yu solvent, after crude drug and solvent are mixed
Under conditions of 60-100 DEG C, stir 2～4h, be collected by filtration and obtain the first filtrate and the first filtering residue；According to described first filtering residue with molten
The ratio that w/v mg/ml is 1:10～20 of agent, the condition of 60-100 DEG C after mixing described first filtering residue and solvent
Lower stirring 1～3h, is collected by filtration and obtains the second filtrate and the second filtering residue, subtracts after described first filtrate and described second filtrate mixing
Pressure concentrates and prepares Chinese medicine extract.
6. the preparation method of the anti-wrinkle eye cream containing Chinese medicine ingredients as claimed in claim 4, it is characterised in that described contain
The raw material of the anti-wrinkle eye cream of medicine composition, counts by weight, including: water 50-55 part, glycerol 2.2-3.8 part, methyl glucoside
Glycoside 20 oxirane 0.6-0.7 part, stearic acid 0.3-0.5 part, siliceous smooth dose of 0.15-0.25 part, hyaluronic acid 0.03-0.04
Part, isomerized sugar 0.4-0.7 part, Flos Rosae Rugosae quintessence oil 0.02-0.04 part, Radix Astragali extract 0.07-0.1 part, cortex acanthopanacis radicis extract 0.07-0.1
Part, Radix Rhodiolae extract 0.07-0.1 part, Herb Gynostemmae Pentaphylli extract 0.07-0.1 part, radix lithospermi extract 0.07-0.1 part.
7. the preparation method of the anti-wrinkle eye cream containing Chinese medicine ingredients as claimed in claim 4, it is characterised in that described contain
The raw material of the anti-wrinkle eye cream of medicine composition, counts by weight, including: 55 parts of water, glycerol 3.5 parts, methylglucoside 20
0.6 part of oxirane, stearic acid 0.4 part, siliceous smooth dose 0.20 part, hyaluronic acid 0.3 part, isomerized sugar 0.6 part, Flos Rosae Rugosae
Quintessence oil 0.04 part, Radix Astragali extract 0.1 part, cortex acanthopanacis radicis extract 0.1 part, Radix Rhodiolae extract 0.1 part, Herb Gynostemmae Pentaphylli extract
0.1 part, radix lithospermi extract 0.1 part.
8. the anti-wrinkle eye cream containing Chinese medicine ingredients, it is characterised in that for using Chinese medicine ingredients as claimed in claim 4
The preparation method of anti-wrinkle eye cream prepares.
9. one kind contains the application in terms of cosmetic skin care product of the anti-wrinkle eye cream of Chinese medicine ingredients as claimed in claim 1.
10. the preparation method of the anti-wrinkle eye cream containing Chinese medicine ingredients as claimed in claim 4 is preparing cosmetic skin care product side
The application in face.
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| CN201610541050.XA CN105943475A (en) | 2016-07-08 | 2016-07-08 | Wrinkle-relieving eye cream containing traditional Chinese medicine components as well as preparation method and application thereof |
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