CN103585096B - A kind of face of living essence and preparation method thereof that compacts - Google Patents
A kind of face of living essence and preparation method thereof that compacts Download PDFInfo
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- CN103585096B CN103585096B CN201310561225.XA CN201310561225A CN103585096B CN 103585096 B CN103585096 B CN 103585096B CN 201310561225 A CN201310561225 A CN 201310561225A CN 103585096 B CN103585096 B CN 103585096B
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- essence
- skin
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- living
- compacts
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Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a kind of emulsion-type face essence that compacts of living, this product is on antioxidant network system basis, add poly-polysaccharide Firm agent, avenabeta glucosan, hyaluronic acid isoreactivity composition, and the multiple Chinese herbal medicine extract such as composite rhodiola root, glossy ganoderma, have stronger anti-oxidant, immediately compact and long-acting moisture-keeping efficacy, good to the repairing effect of skin barrier damage. Use continuously this essence, wrinkle obviously shoals, and that skin becomes is smooth, compact, soft, tender white.
Description
Technical field
The present invention relates generally to a kind of face of living essence that compacts, and relates in particular to a kind of face of living compact essence and system thereofPreparation Method.
Background technology
Mid-term the 1950's, Harman founded old and feeble free radical theory, and this theory thinks that aging isFree radical (being mainly oxygen radical) causes harmful attack of cell component. Free radical refers to notMolecule, atom or the ion of paired electrons, have active chemical property, easily occurs with other contiguous moleculesReaction. In overwhelming majority's reaction, the easy chain-react of free radical a: free-radical generating goes out otherIndividual free radical, unpaired electronics is passed to another molecule from a molecule; When two free radicals meet alsoWhile being combined into duplet, this chain reaction just can stop. Free radical is human homergy's product, normalUnder physiological situation, in the dynamic equilibrium of the free radical in human body in continuous generation and elimination. In human body, exist fewAmount free radical not only human body is not constituted to threat, but also can help transmit sustain life power energy, disappearExcept inflammation, decomposition noxious material etc. If the quantity of people's interior free yl is gathered too much, will cause lipid mistakeOxidation, destroys eucaryotic cell structure, affects the eubolism of human body, causes disease, accelerates the process of human senility.
Under normal circumstances, all there is the anti-oxidative defense system of a set of complete removing interior free yl in organismSystem, they can or stop it that oxidation reaction further occurs by direct removing free radical indirectly, to reduce lifeBecome stronger free radical and the intermediate product of toxic action. But, with advancing age, in body, produce freelyBase scavenger is that the ability of antioxidant declines gradually, thereby has weakened the defence capability to free radical damage, makesBody tissue organ is easily impaired, has accelerated the aging of body, causes a series of disease. In order to prevent this type ofThe generation of phenomenon, can supplement artificially antioxidant, thereby reach defence disease, the object delaying senility.
Conventional antioxidant comprises that enzyme antioxidant is as superoxide dismutase (SOD), catalase(CAT), glutathione peroxidase (GSHP), coenzyme (CoQ10) etc., and non-enzyme antioxidant is as dimensionRaw plain A (VA), vitamin C (VC), vitamin E (VE), beta carotene, alpha-lipoic acid (LA), paddy Guang are sweetThe materials such as peptide (GSH) and zinc, selenium. From plant or Chinese herbal medicine, also can extract to separate and obtain having removing free radicalThe bioactivator of effect, as flavonoids, triterpenes, curcumin, Anthraquinones, polysaccharide, saponin classAnd the compound that contains phenolic hydroxyl structure etc., this class material is being given full play to antioxidant or free radical scavengerBiological effect, thus play the effect of protecting body.
Between antioxidant content, often there is anti-oxidant synergy. Pluralistic theory thinks, multiple antioxidant canReparative regeneration mutually, form redox cycle system, thereby it is single anti-oxidant that antioxidation activity is significantly better thanAgent. Based on this, the famous professor of Univ California-Berkeley, the international free radical chairman LestPaker of associationThe scholars such as doctor propose free radical scavenger chain reaction and antioxidant network technology, and they are by clear and clear and definite ratioBe likened to the old and feeble pattern of latest modern technological Effective Anti, be considered to revolutionary in free radical biomedicine and anti-ageing fieldTheory. In this theory, there is the representative theory of two special significants: one is antioxidantSystem or antioxidant network; Another is the compound chain reaction of antioxidant or the compound chain of antioxidant.
In this antioxidant series, VC, VE, CoQ10, LA and GSH drafted as antioxidant network skillThe essence of art and core. Its main cause is: the first, and body itself can not produce VC and VE, must be from foodIn thing, obtain. The second, although body can produce CoQ voluntarily10, LA, GSH, but with advancing age,Their levels in vivo obviously decline. The 3rd, these 5 kinds of antioxidants all have wide spectrum, efficient free radicalRemoving ability, and can mutually supplement each other, Synergistic. The 4th, 5 kinds of antioxidants all respectively haveIt is different from the unique effect of other antioxidants. The 5th, in body, between these 5 kinds of antioxidants, existInteract, and can mutually regenerate, make to have entered each other recirculation, thereby form network, greatly strengthenThe function of antioxidant. This network is resist toxic damages taking free radical as mediation main in vivoSpecial effect is finally being brought into play in defence line in the process that improves body resistance against diseases and delay senility.
Antioxidant network system is the important umbrella that defence organism crosses presenility, the lost of life, their associatingsEffect, can significantly improve biologically active each other, and energy Synergistic, contributes to organism to remove free radicalTo keep good anti-oxidant poised state. Reaction equation (1)～(10) have illustrated in this antioxidant network system fivePlant the principle that antioxidant supplements mutually, Synergistic is removed free radical. (1) in formula LOO be fat peroxy fromBy base.
LOO·+VE→LOOH+VE·(1)
LOO·+VC→LOOH+VC·(2)
VE·+VC→VE+VC·(3)
VC·+VE→VC+VE·(4)
VE·+GSH→VE+GSSG(5)
VC·+GSH→VC+GSSG(6)
GSSG+CoQ10H2→2GSH+CoQ10(7)
LA+VC·→VC+LA·(8)
LA+VE·→VE+LA·(9)
LA·+H·→LA(10)
These 5 kinds of antioxidants can also with other antioxidant use in conjunction, as carried with SOD, natural plantsGet thing, epithelical cell growth factor (EGF), natural hormone, skin moisturizer, skin-nourishing agent and skin anti-Shining agent etc. can use in conjunction, to play a positive role and complementary advantage, makes anti-aging cosmetics performance more aobviousThe effect of work.
China is the cradle of Chinese herbal medicine, and the application of Chinese herbal medicine aspect health and beauty has more than 3,000 year going throughHistory. Chinese herbal medicine extract is for cosmetics, can play moisturizing, whitening, sun-proof, anti-oxidant, delay senility,Promote skin immunity, promote the objects such as skin health. At present, having had on the market many moneys to add Chinese herbal medicine carriesGet the cosmetics of thing, but Chinese herbal medicine extract and antioxidant network system are combined and be applied in cosmeticsRarely seen report of research.
Essence, is the superfine product in skin care item, compared with emulsion, cream kind cosmetics, and its composition exquisiteness, meritImitate powerful, effect is remarkable, can play the effect of " comfort in peace outer ". Supplement on the one hand skin needed as far as possibleNutrition, moisture, strengthening skin natural resistance, resists the infringement of external environment, allows skin recover as early as possible normal;On the other hand, stimulate maintenance and the renewal of accelerating cell, allow skin more become clear, to compact. The contained work of essenceProperty constituent concentration in all cosmetics, be the highest, and general quality is thinner, easily transmits into skinDeep layer, is absorbed by the skin better, the amount of playing half merit effect doubly. The present invention is taking cosmetics emulsion theory as basePlinth screening matrix formulations, is used for instructing answering of active component by theoretical antioxidant network system and drug matching theoryJoin, add multiple antioxidant, skin moisturizer, Chinese herbal medicine extract isoreactivity composition, develop and haveThe essence of strong anti-oxidation, moisturizing, crease-resistant, the effect of compacting; Simultaneously the sense organ to essence and physical and chemical index,Moisture retention, non-oxidizability are tested, and repairing effect to skin barrier damage and long-term effect after on probationMake an appraisal.
Summary of the invention
The object of the invention is just to provide a kind of face of living essence and preparation method thereof that compacts.
The present invention is achieved by the following technical solutions:
A kind of face of living essence that compacts, the compact formula of essence of described face alive is:
The compact preparation method of essence of the face of living, comprises the following steps:
Above-mentioned A phase and B are placed in respectively to 75-80 DEG C of water-bath mutually and stir 25-30min, make decorating film moltenSeparate; C is added to A phase, while stirring B is added to; After rapid stirring 25-30min, lower the temperature; ColdBut, during to 40-45 DEG C, respectively D phase, E phase and F are added to and are stirred to evenly; Temperature is down to 30-35 DEG CIn time, stops stirring, and discharging, obtains the described face alive essence that compacts.
The compact preparation method of essence of the face of living, in preparation process for making manufactured goods total amount remain 100G, can add appropriate distilled water cooling time.
Advantage of the present invention is:
Antioxidant network system is used for to formula, and adds multiple other antioxidants, to bring into play oxidation resistant associationSame synergistic effect; Add poly-polysaccharide Firm agent, multiple NMF, product is had immediately lift to compact and long-actingMoisture-keeping efficacy; Select the emulsifying matrix formulations as carrier, be convenient to water-soluble and fat-soluble various active compositionDissolve; Part active component adopts nanoemulsions and microcapsules technology, has both been beneficial to transmission and the skin of active componentAbsorption, increased again the stability of product; Soft in formula, essence, parabens, gentle nothingStimulate.
VCE in the present invention formula is not affect biologically active and truly can variable colorVitamin C derivative, thereby after entering skin, decomposed by enzyme the effect of bringing into play VC; Effectively check melanin is thin for itBorn of the same parents' is synthetic, prevents and desalinates color spot, can also improve skin gloss simultaneously, repairs Skin Cell activity, promotesThe formation of collagen, has the function that prevents skin senescence. Vitwas E is the stable derivatives of VE,It is decomposed into VE after penetrating skin, thereby produces antioxidation activity, and protection skin exempts from the injury of free radical;It can also promote skin metabolism, improves the elasticity of skin, prevents pigmentation etc. Glutathione is tool not onlyThere is non-oxidizability, can also affect Skin Cell tyrosinase activity, check melanin generation, prevent skin-colorThe generation of spot. Retinol Palmitate has anti aging effect, the effect such as anticancer. Resveratrol can be removed certainlyBy base, anti-oxidant, anti-ageing, the activity of inhibition intracellular tyrosine enzyme, stops melanic formation. Sulphur is pungentAcid has strong anti-oxidation, has concurrently water-solublely and fat-soluble, be easy to skin and absorb, for livid ring around eye, wrinkle andThe usefulness such as spot are distinguished, can also improve skin dim heavy, careful pore. Ubiquinone10Can effectively remove free radical,Prevent skin senescence, promote skin metabolism, reduce the generation of wrinkle, also have anti-Pigmented effect.In formula, select to add the nanoemulsions of Co-Q10 and lipoic acid, have that particle diameter is little, skin compatibility is good andClosed effect on skin, can effectively promote the permeability of active component on skin, raising active materialAbsorb.
Niacinamide (Cobastab3) the effectively generation of check melanin cell, skin whitening. Panthenol claims again dimensionRaw plain former B5, be the NMF of deep infiltration, can stimulate epithelial growth, promote wound healing, rise and disappearScorching effect. Avenabeta glucosan has moisturizing, anti-ageing, anti-wrinkle, promotes wound healing, and repair and shine rear damage,Desalination scar, the multiple efficacies such as anti-quick anti-inflammatory. Sodium Hyaluronate is called as optimal NMF, and it can be heldKubo is wet, makes skin tender, smooth; Also can promote the absorption of other active components and nutriment, improve skinThe Nutrition and Metabolism of skin, for dermal collagen and elastomer synthetic provides good environment, alleviates aging wrinkleLine vestige, prevents aging. Poly-polysaccharide Firm agent has instantaneous level and smooth skin quality and lifts effect, makes skin plastotype tightReal.
Glossy ganoderma, ginseng, the Radix Astragali, Radix Angelicae Sinensis, rhodiola root all belong to help class Chinese medicine, and glossy ganoderma is invigorated the spleen and benefited qi, ginsengMend strengthening spleen and lung, Radix Astragali invigorating qi for strengthening superficies, Radix Angelicae Sinensis blood circulation promoting and enriching, rhodiola root promoting blood circulation and hemostasis. According to traditional Chinese medical science compatibility theory,Glossy ganoderma and ginseng, the Radix Astragali, Radix Angelicae Sinensis compatibility, have the effect that increases blood-enrich. Be added on cosmetics as active componentIn, effect that they are also had nothing in common with each other: glossy ganoderma, ginseng extract have anti-oxidant delay skin aging, liftingThe multiple efficacies such as cutaneous immunisation power; Astragalus Root P.E can promote the synthetic of collagen, promotes skin elasticity; WhenReturn the activity of extract energy restraint of tyrosinase, have certain white-skinned face function; Gadol extract has very strongNon-oxidizability, the injury that can resist multiple radical pair skin.
The sense organ of essence of the present invention and physical and chemical index all meet China's moisturizing lotion professional standard requirement, haveAnti-oxidant, moisturizing, compact, desalinate the multi-efficiencies such as pigment, good to the repairing effect of skin barrier damage, connectContinuous this work face essence that compacts that uses, wrinkle obviously shoals, skin become water moisten, compact, pale, tender.
Brief description of the drawings
Fig. 1 is face compact essence hydroscopicity and the time chart of living;
Fig. 2 is that each index returns to the front horizontal number of damage and time chart;
Fig. 3 is the face essence skin trial effect statistical chart that compacts of living;
Fig. 4 is skin contrast before and after product beta test, and a is for before on probation, and b is for after on probation.
Detailed description of the invention
Embodiment 1
A kind of face of living essence that compacts, the compact formula of essence of described face alive is:
The compact preparation method of essence of the face of living, comprises the following steps:
Above-mentioned A phase and B are placed in respectively to 75-80 DEG C of water-bath mutually and stir 25-30min, make decorating film moltenSeparate; C is added to A phase, while stirring B is added to; After rapid stirring 25-30min, lower the temperature; ColdBut, during to 40-45 DEG C, respectively D phase, E phase and F are added to and are stirred to evenly; Temperature is down to 30-35 DEG CIn time, stops stirring, and discharging, obtains the described face alive essence that compacts.
Performance test
Organoleptic properties evaluation
Whether fine and smooth get the face alive essence visual observations particle under room temperature and non-direct sunlight that compacts, whether color and lusterUniformity; Differentiate that with sense of smell whether smell is pure.
The test of pH value
Take the face alive essence sample 3.0g that compacts, put into the small beaker that fills 30mL water, at 40 DEG CHeating for dissolving. Measure the pH value of the essence aqueous solution with the pH meter of having proofreaied and correct.
Centrefuge experiment
The face essence sample that compacts of living is packed in the centrifuge tube of 10mL, with the centrifugal 30min of 3000r/min,Observation has or not lamination.
Heat-resisting, cold-resistant test
The face of the living essence sample that compacts is positioned in the freezer compartment of refrigerator of the constant temperature oven of 40 DEG C and-10 DEG C to 24After h, take out, recover to observe whether have layering, precipitation or water outlet phenomenon after room temperature.
Non-oxidizability test
Take the face alive essence 1.00g that compacts, after dissolving with distilled water, proceed to constant volume in 10mL volumetric flask. WithThis dilutes for original solution, and preparation mass concentration is 2.00 × 10-3The sample solution of g/mL, carries out anti-oxidantProperty is tested.
(1) clearance rate to DPPH free radical
Getting respectively above-mentioned sample solution and amount of substance concentration is 2.00 × 10-4The DPPH absolute ethyl alcohol of mol/LThe each 3mL of solution adds in same tool plug test tube, shakes up, and lucifuge is placed after 30min, uses ultraviolet-visible light splittingPhotometric determination mixed solution is in the absorbance A at 517nm placei1, measure each extractant and the 3mL of 3mL simultaneouslyThe mixed absorbance A of DPPH solution01With 3mL sample solution and the mixed extinction of 3mL absolute ethyl alcoholDegree Aj1, calculate clearance rate P according to formula1：
P1＝[1－(Ai1－Aj1)/A01]×100%
(2) clearance rate to OH free radical
Getting 2mL amount of substance concentration is 1.00 × 10-2The salicylic acid solution of mol/L, FeSO4After solution and dilutionSample solution add in same tool plug test tube, then adding 2mL amount of substance concentration is 8.80 × 10-2The H of mol/L2O2Solution, shakes up rear startup reaction, reacts after 30min, at 510nm in 37 DEG C of water-bathsPlace measures absorbance Ai2; Replace salicylic acid solution to measure absorbance A with 2mL distilled waterj2; Distill with 2mLWater replaces sample solution to measure absorbance A02. Calculate clearance rate P according to formula2：
P2=[1－(Ai2－Aj2)/A02]×100%
(3) to O2 ￣The clearance rate of free radical
Get pH and be 8.2 Tris-HCl cushioning liquid 5mL in tool plug test tube, preheating 20 in 25 DEG C of water-bathsAfter min, adding successively sample solution 2mL and 0.5mL amount of substance concentration is 5.00 × 10-3The adjacent benzene three of mol/LPhenates acid solution, shakes up immediately, in 25 DEG C of water-baths, reacts 4min, measures immediately its extinction at 320nm placeDegree Ai3; With 1.00 × 10-2The HCl solution 0.5mL of mol/L replaces pyrogallol hydrochloric acid solution, measures absorbance Aj3; With the above-mentioned different sample solutions of 2mL distilled water replacement, measure absorbance A03. Calculate and remove according to formulaRate P3：
P3=[1－(Ai3－Aj3)/A03]×100%
Hydroscopicity test
Take the 5.00g face essence that compacts of living, be placed in the measuring cup that diameter is 4cm, at room temperature, putPut 8h in the environment of relative humidity 43%, 75%, the variation that weighs and record each sample quality every 1h,Calculate hydroscopicity.
Wherein mnFor placing sample quality after n hour, g; m0For placing front testing sample quality, g.
Skin experiment on probation
(1) the repairing effect test to skin barrier damage
Select 20 people as tester, be divided into 2 groups. With inboard arm 3 × 3cm2Place is portion on probationPosition, cleans, and tests with skinanalysis apparatus. Test with 50% ethanolic solution wiping 5min first group of surveyAfter the indoor standing 20min of examination personnel, smear sample, with skinanalysis apparatus test, survey every 1h afterwards immediatelyTry 1 time, observe trial effect. Ethanolic solution wiping is complete is left intact with 50% for second group of tester,Every 1h test 1 time, observation of nature repairing effect.
(2) skin is tested for a long time
Select 20 people as tester, the mean age was 35 one full year of life, the on probation face of living of the face essence that compacts,Every day is each use 1 time sooner or later, shares 42 days, with skinanalysis apparatus test, observes trial effect week about.
Test result
Sense organ and physical and chemical index measurement result
Non-oxidizability
The face of the living essence that compacts is 2.00 × 10 in mass concentration-3When g/mL to DPPH, OH and O2 ￣3 kinds certainlyBe respectively 60.4%, 81.3%, 70.3% by the clearance rate of base, illustrate that the face of the living essence that compacts has more anti-Oxidisability;
The compact moisture retention of essence of the face of living
Fig. 1 compacts essence at ambient temperature for the face of living, and when relative humidity is respectively 43% and 75%, protectsWet rate and time chart. Can find out, under room temperature condition, when relative humidity is 75%, the face of the living essence of compactingThe plain hydroscopicity of China declines slowly, is only-0.43% after 8h; When relative humidity is 43%, the face of the living essence of compactingThe plain hydroscopicity of China declines during compared with relative humidity 75% fast, but is only also-0.61%. Can find out, the face of living is tightThe moistening effect that causes essence is better.
To the repairing effect test of skin barrier damage
Ethanol can be partly dissolved Stratum corneum lipids composition, destroys original structure, causes barrier function damage, mainShow as skin oil content, moisture, elasticity, collagen content decline. Fig. 2 is that first group of subject usesThe face of the living essence that compacts is smeared after damage location, and each index returns to number and the time relationship of level before damageFigure. After smearing, there is 6 experimenters' the oil content content to recover normal level before damage, whole experimenters after 1hOil content recovers the front normal level of damage; After smearing, there is 7 experimenters' moisture to recover to damage front normalLevel, after 2h, all experimenter's moisture is recovered the front normal level of damage; After smearing, there are 3 experimentersSkin elasticity returns to normal level before damage, has 7 experimenter's skin elasticities just to return to before damage after 8hOrdinary water is flat; After smearing, have 4 collagen contents return to damage before normal level, after 8h, have 6 testedPerson's collagen content returns to the front normal level of damage. Second group of subject repairs naturally, oil content after 8h,The number that moisture, elasticity, collagen content return to the front level of damage is respectively 7,4,2,2. CanFind out, smear the face alive injured skin after essence that compacts and all repair to some extent, all experimenters' oil content and moisture containAmount just can return to the front normal level of damage at short notice, and skin elasticity and collagen content recover numberAlso all more than 6 people, be significantly higher than nature repairing effect, illustrate that the face of the living essence that compacts damages skin barrierRepairing effect more remarkable.
Skin is tested for a long time
With advancing age, the moisture of human body skin, elasticity, collagen fabric content all can be constantly underFall, and lack of water will be destroyed the water oil balance of skin, causes skin to secrete more oil content, pigment content along withGrowth, the solar radiation etc. at age, also can increase gradually. The on probation face of living of subject is compacted before and after essenceMoisture, oil content, elasticity, collagen and pigment content in skin are tested, to try out number of days as horizontal seatMark, the each index variation of skin number is ordinate mapping. As seen from Figure 3,20 subjects are on probationThe face of living is compacted after essence, the vicissitudinous number of each index. Along with the prolongation of number of days on probation, moisture, elasticity,The tested number that collagen content improves increases gradually, and the number that after 42 days, these 3 indexs are improved respectivelyBe 18,12,14; And oil content and pigment content be along with number of days on probation extends, the subject who reduces gradually alsoConstantly increase, after 42 days, these 2 indexs are compared the front number reducing on probation and are respectively 17 and 10. 70%Subject's reaction, the skin that can significantly feel for first week on probation becomes soft, smooth, water profit, continuously examinationWith after 42 days, 85% experimenter can significantly see the variation of skin. Fig. 4 for 44 one full year of life wherein,Experimenter's front comparison diagram with trying out skin after 42 days on probation of Dry. Can find out on probation 42Dermatoglyph after it obviously shoals, and it is pale glossy that skin also becomes. Test result shows, the face of living on probation continuouslyThe essence wrinkle that compacts obviously shoals, and skin becomes water profit, pale, soft flexible.
Claims (3)
1. the face of the living essence that compacts, is characterized in that the compact formula of essence of described face alive is:
2. the face alive as claimed in claim 1 preparation method for essence of compacting, is characterized in that comprisingFollowing steps:
Above-mentioned A phase and B are placed in respectively to 75-80 DEG C of water-bath mutually and stir 25-30min, make decorating film moltenSeparate; C is added to A phase, while stirring B is added to; After rapid stirring 25-30min, lower the temperature; ColdBut, during to 40-45 DEG C, respectively D phase, E phase and F are added to and are stirred to evenly; Temperature is down to 30-35 DEG CIn time, stops stirring, and discharging, obtains the described face alive essence that compacts.
3. a kind of face of living according to claim 2 preparation method of essence of compacting, is characterized in thatIn preparation process, for making manufactured goods total amount remain 100g, cooling time, can add appropriate distilled water.
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| CN104473791A (en) * | 2014-12-10 | 2015-04-01 | 唯美度科技（北京）有限公司 | Breathable double-effect fresh protective emulsion |
| CN104688553A (en) * | 2015-02-06 | 2015-06-10 | 深圳唯美度生物科技有限公司 | Emulsion containing lipoic acid and preparation method of emulsion |
| CN104958242A (en) * | 2015-07-31 | 2015-10-07 | 桂林市宏旭生物科技有限公司 | Anti-ultraviolet mask liquid and preparation method thereof |
| CN104958240A (en) * | 2015-07-31 | 2015-10-07 | 桂林市宏旭生物科技有限公司 | Freckle expelling facial mask and preparation method thereof |
| CN104971029A (en) * | 2015-07-31 | 2015-10-14 | 桂林市宏旭生物科技有限公司 | Whitening mask and preparation method thereof |
| CN104983646A (en) * | 2015-07-31 | 2015-10-21 | 桂林市宏旭生物科技有限公司 | Night maintenance mask solution and preparation method thereof |
| CN105434266A (en) * | 2015-12-20 | 2016-03-30 | 青岛海特新蓝生物科技有限公司 | Whitening cosmetic containing rhodiola-rosea extractive, ginseng extractive and ganoderma-lucidum extractive |
| CN107137260A (en) * | 2017-04-05 | 2017-09-08 | 北海市韩能生物科技有限公司 | Toner |
| CN107095828B (en) * | 2017-07-03 | 2020-08-11 | 四川省中医药科学院 | Daily chemical product composition with skin barrier repair function and preparation method and application thereof |
| CN107383167B (en) * | 2017-08-07 | 2021-02-09 | 温州千瑞生物科技有限公司 | Antioxidant active peptide and application thereof |
| CN107998027A (en) * | 2017-12-24 | 2018-05-08 | 姚佑灿 | A kind of antiradiation injury repairs breast |
| CN108354869A (en) * | 2018-04-28 | 2018-08-03 | 广东巴松那生物科技有限公司 | A kind of essence lotion and preparation method thereof that fixes of the coreopsis tinctoria extract containing Tianshan Mountains |
| CN109394671A (en) * | 2018-12-18 | 2019-03-01 | 韩孝 | The composition and its preparation method and application of albumen bracket firm skin |
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