CN103598460A - Forage for preventing infectious bronchitis of chicken - Google Patents
Forage for preventing infectious bronchitis of chicken Download PDFInfo
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Abstract
The invention provides a forage for preventing the infectious bronchitis of chicken. The forage is characterized in that the forage comprises corn, soybean meal, salt, fish meal, bone meal, a trace element additive, an amino acid additive, a vitamin additive, and a traditional Chinese medicinal immune powder feed additive used for preventing the infectious bronchitis of chicken. The forage has a substantial effect on the prevention of the infectious bronchitis of chicken, and has the advantages of non-toxicity, drug resistance and no drug residual.
Description
Technical field
The present invention relates to traditional Chinese medicine technical field, relate in particular to a kind of for preventing the feed of infectious bronchitis of chicken.
Background technology
Infectious bronchitis of chicken (Infectious Bronchitis, IB) be by IBV (Infectious Bronchitis Virus, IBV) a kind of acute height contagious disease causing, infected chicken is because of growth retardation, feed consumption increases, lays eggs and egg matter declines, death rate increases, and to poultry husbandry, causes tremendous economic loss.In order effectively to prevent and control the generation of this disease, existing vaccine immunity and the western medicines of adopting, because IBV strain has the feature of highly easily variation and many serotypes, and make immunity inoculation complicated more, are difficult to control.At present, China mainly prevents and treats infectious bronchitis of chicken with Western medicine, but because Western medicine mainly excretes via renal metabolism, and the kidney damage being caused by this disease is put aside medicine in vivo in a large number, the unsatisfactory curative effect sick to this not only, but also easily produce a toxic reaction to a drug.
Chinese medicine animal organism physiological function being carried out to comprehensively regulating, improve body immunity, premunition and the aspect such as antiviral have distinctive feature, effectively prevention and control and treat this disease.Chinese veterinarian thinks that infective bronchitis is mainly that heat poison, wet poison, epidemic disease accumulate in malicious, causes that sputum blocks tracheae, causes coughing and breathes heavily, stream nose liquid, cough to breathe heavily and injure healthy tendency, cause the failure of the kidney in receiving air, Wei Yang does not fill, and in lower void, contains, suffer from a deficiency of the kidney and can not normally evaporate water liquid, therefore the cold limb of shape is cold, ight soil is abnormal.
The dirty pathology and disease mechanism of the Clinical symptoms of infectious bronchitis of chicken and traditional Chinese veterinary medicine lung, spleen, kidney three is closely related, theoretical according to Chinese veterinarian, infectious bronchitis of chicken is the evil lung of violating of plague poison, phlegm is turbid to be jammed, cause that lung loses that a surname is respectful, qi stagnation hemagglutination, body fluid lose due to the spreading, its disease at all at lung, Syndrome Differentiation of Traditional Chinese Medicine is in the majority with affection of exogenous wind-heat, minority is syndrome of superficies cold and interior heat, all belongs to heat and is defending minute or disease involving weifen and qifen.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for preventing Chinese medicine immune formulation and the feed of infectious bronchitis of chicken, and it has significant effect in prevention aspect infectious bronchitis of chicken, and have nontoxic, the advantage of resistance, drug residue free.
For solving the problems of the technologies described above, the invention provides a kind ofly for preventing the Chinese medicine immune formulation of infectious bronchitis of chicken, its bulk drug comprises Glabrous Sarcandra Herb, the root of large-flowered skullcap, great burdock achene, edible tulip, cape jasmine, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, fritillaria thunbergii, the fruit of Chinese magnoliavine, climbing groundsel, gynostemma pentaphylla, bush, date, subprostrate sophora, adenophora tetraphylla, the calyx and receptacle of a persimmon, hawthorn, radish seed, hairy euphorbia, Gorgon fruit, wilsonii, radix fici simplicissimae and Japanese cryptotaenia stem and leaf.
Wherein, in described Chinese medicine immune formulation, the weight portion of each bulk drug is respectively: Glabrous Sarcandra Herb 25 weight portion～35 weight portions, the root of large-flowered skullcap 45 weight portion～55 weight portions, great burdock achene 25 weight portion～35 weight portions, edible tulip 35 weight portion～45 weight portions, cape jasmine 45 weight portion～55 weight portions, the tubers of dwarf lilyturf 55 weight portion～65 weight portion, sealwort 45 weight portion～55 weight portions, radix pseudostellariae 75 weight portion～85 weight portions, the vine of multiflower knotweed 35 weight portion～45 weight portions, the fruit of Chinese wolfberry 55 weight portion～65 weight portions, fritillaria thunbergii 20 weight portion～30 weight portions, the fruit of Chinese magnoliavine 25 weight portion～35 weight portions, climbing groundsel 20 weight portion～30 weight portions, gynostemma pentaphylla 45 weight portion～55 weight portions, bush 20 weight portion～30 weight portions, date 35 weight portion～45 weight portions, subprostrate sophora 25 weight portion～35 weight portions, adenophora tetraphylla 45 weight portion～55 weight portions, the calyx and receptacle of a persimmon 20 weight portion～30 weight portions, hawthorn 25 weight portion～35 weight portions, radish seed 20 weight portion～30 weight portions, hairy euphorbia 25 weight portion～35 weight portions, Gorgon fruit 35 weight portion～45 weight portions, wilsonii 30 weight portion～40 weight portions, radix fici simplicissimae 30 weight portion～40 weight portions and Japanese cryptotaenia stem and leaf 20 weight portion～30 weight portions.
Wherein, in described Chinese medicine immune formulation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 28 weight portion～32 weight portions, the root of large-flowered skullcap 48 weight portion～52 weight portions, great burdock achene 28 weight portion～32 weight portions, edible tulip 38 weight portion～42 weight portions, cape jasmine 48 weight portion～52 weight portions, the tubers of dwarf lilyturf 58 weight portion～62 weight portion, sealwort 48 weight portion～52 weight portions, radix pseudostellariae 78 weight portion～82 weight portions, the vine of multiflower knotweed 38 weight portion～42 weight portions, the fruit of Chinese wolfberry 58 weight portion～62 weight portions, fritillaria thunbergii 23 weight portion～27 weight portions, the fruit of Chinese magnoliavine 28 weight portion～32 weight portions, climbing groundsel 23 weight portion～27 weight portions, gynostemma pentaphylla 48 weight portion～52 weight portions, bush 23 weight portion～27 weight portions, date 38 weight portion～42 weight portions, subprostrate sophora 28 weight portion～32 weight portions, adenophora tetraphylla 48 weight portion～52 weight portions, the calyx and receptacle of a persimmon 23 weight portion～27 weight portions, hawthorn 28 weight portion～32 weight portions, radish seed 23 weight portion～27 weight portions, hairy euphorbia 28 weight portion～32 weight portions, Gorgon fruit 38 weight portion～42 weight portions, wilsonii 33 weight portion～37 weight portions, radix fici simplicissimae 33 weight portion～37 weight portions and Japanese cryptotaenia stem and leaf 23 weight portion～27 weight portions.
Wherein, in described Chinese medicine immune formulation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 30 weight portions, the root of large-flowered skullcap 50 weight portions, great burdock achene 30 weight portions, edible tulip 40 weight portions, cape jasmine 50 weight portions, the tubers of dwarf lilyturf 60 weight portion, sealwort 50 weight portions, radix pseudostellariae 80 weight portions, the vine of multiflower knotweed 40 weight portions, the fruit of Chinese wolfberry 60 weight portions, fritillaria thunbergii 25 weight portions, the fruit of Chinese magnoliavine 30 weight portions, climbing groundsel 25 weight portions, gynostemma pentaphylla 50 weight portions, bush 25 weight portions, date 40 weight portions, subprostrate sophora 30 weight portions, adenophora tetraphylla 50 weight portions, the calyx and receptacle of a persimmon 25 weight portions, hawthorn 30 weight portions, radish seed 25 weight portions, hairy euphorbia 30 weight portions, Gorgon fruit 40 weight portions, wilsonii 35 weight portions, radix fici simplicissimae 35 weight portions and Japanese cryptotaenia stem and leaf 25 weight portions.
The present invention also provides the preparation method of above-mentioned Chinese medicine immune formulation, is specially:
The first step, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, gynostemma pentaphylla, date, adenophora tetraphylla, Gorgon fruit and wilsonii are mixed in proportion, getting mixture 100g packs in percolator, white wine 600g～the 800g that adds 50 ℃～55 ℃, under the condition of 25 ℃～35 ℃, soak 20 hours～30 hours, regulate percolator valve, white wine liquid is slowly oozed, and the speed of oozing is 2～4mL per minute, collects drip, obtain the percolate of 700mL～1L, concentrated, remove white wine, dry, pulverize, obtain the first dried powder;
Second step, mixes remaining component in proportion, gets 100g mixture, the water that adds 500g～800g, boils 3～4 hours, filters, obtain the first filtrate, filter residue adds the water of 200g～300g again, again boils 1～2 hour, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder;
The 3rd step, mixes the first dried powder and the second dried powder, obtains Chinese medicine immune formulation powder.
It is a kind of for preventing the feed of infectious bronchitis of chicken that the present invention also provides, and its raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamin(e) supplement and for preventing the Chinese medicine immune formulation powder feed addictive of infectious bronchitis of chicken.
Wherein, in described feed, the weight portion of each material composition is respectively corn 90 weight portion～110 weight portions, dregs of beans 30 weight portion～50 weight portions, salt 2 weight portion～4 weight portions, fish meal 8 weight portion～12 weight portions, bone meal 3 weight portion～5 weight portions, trace mineral supplement 2 weight portion～4 weight portions, amino acid additive 2 weight portion～4 weight portions, vitamin(e) supplement 2 weight portion～4 weight portions and Chinese medicine immune formulation powder feed addictive 15 weight portion～20 weight portions.
Wherein, in described feed, the weight portion of each material composition is respectively corn 100 weight portions, dregs of beans 40 weight portions, salt 3 weight portions, fish meal 10 weight portions, bone meal 4 weight portions, trace mineral supplement 3 weight portions, amino acid additive 3 weight portions, vitamin(e) supplement 3 weight portions and Chinese medicine immune formulation powder feed addictive 18 weight portions.
The present invention also provides the preparation method of above-mentioned feed, is specially:
The first step, prepares described Chinese medicine immune formulation powder feed addictive according to the method described above;
Second step, puts into fodder mixing machine together with the described Chinese medicine immune formulation powder feed addictive that other raw material components in feedstuff and the first step are obtained, and continuous uniform stirred after 1～3 hour, put into pulverizer and pulverized, and obtained feed.
Beneficial effect of the present invention:
Feed provided by the invention has significant effect in prevention aspect infectious bronchitis of chicken, and have nontoxic, the advantage of resistance, drug residue free.
The specific embodiment
Chinese veterinarian treats infective bronchitis and adheres to the eliminating evil and large principle of righting two, and eliminating evil is the heresy of dispelling the harmful cause of disease-epidemic disease poison, suppresses or eliminates virulence factor, gets rid of pathological product.Righting is by strengthening the premunition of body, improve immunologic function, righting is widely used in various infectious diseases all the time, basic principle is yin-nourishing Bao Jin, and can directly the degrade toxin of pathogen of medicinal herb components can also strengthen the immunologic function of body, by the clearing heat and detoxicating virus that suppresses, be aided with clearing heat and eliminating phlegm, antiasthmatic-antitussive reaches eliminating evil object, and collaborative help class Chinese medicine strengthens immunity of organisms jointly, reaches the object of righting.
Theoretical according to traditional Chinese veterinary medicine, infectious bronchitis of chicken be in epidemic disease poison, invade due to, belong to warm heat disease category, the clinical Qi phase syndrome marquis with accumulation of heat in the lung is the most common, accumulation of heat in the lung clearly should mistake department, the heap soil or fertilizer over and around the roots of circulation of vital energy in the wrong direction phlegm, therefore be shown in the diseases such as cough, asthma.Because its characteristic of disease belongs to heat, sick position is at lung, and controlling should be clearing heat and detoxicating, should lung relieving asthma, relieving cough and reducing sputum.
Based on above-mentioned theory of traditional Chinese medical science, the present invention proposes to invigorate the spleen and benefit qi, and yin-nourishing Bao Jin is main, be aided with clearing heat and detoxicating, should lung relieving asthma, relieving cough and reducing sputum, realize the prevention to infectious bronchitis of chicken.
The invention provides a kind ofly for preventing the Chinese medicine immune formulation of infectious bronchitis of chicken, its bulk drug comprises Glabrous Sarcandra Herb, the root of large-flowered skullcap, great burdock achene, edible tulip, cape jasmine, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, fritillaria thunbergii, the fruit of Chinese magnoliavine, climbing groundsel, gynostemma pentaphylla, bush, date, subprostrate sophora, adenophora tetraphylla, the calyx and receptacle of a persimmon, hawthorn, radish seed, hairy euphorbia, Gorgon fruit, wilsonii, radix fici simplicissimae and Japanese cryptotaenia stem and leaf.
Further, described Chinese medicine immune formulation only consists of above-mentioned raw materials medicine.
In side, Glabrous Sarcandra Herb anti-inflammation, containing isofraxidin, fumaric acid, butanedioic acid, lignum-vitae base lignan, can improve energetic supersession, broad-spectrum antiseptic, virus replication, immunologic function is had to dual regulation, the root of large-flowered skullcap is clearing heat and detoxicating has the effect of the bronchial spasm of releasing, great burdock achene preventing phlegm from forming and stopping coughing, clearing throat, edible tulip is clearing heat and detoxicating, reducing phlegm and resolving masses, cape jasmine soothing liver-qi stagnation, clearing heat and promoting diuresis, the tuber of dwarf lilyturf Yin nourishing and lung moistening, preventing phlegm from forming and stopping coughing, sealwort, radix pseudostellariae, the contained saponin(e of wilsonii, polysaccharide, flavonoids, organic acid and vitamin isoreactivity composition, have and reinforce vital energy, multiple arteries and veins is admittedly de-, reinforce the spleen to benefit the lung, promote the production of body fluid, the effect of calming the nerves, can significantly improve body's immunity and anti-stress ability, there is antiviral activity, the vine of multiflower knotweed can promote hematopoiesis function, there is tonic effect, cough-relieving that the fruit of Chinese wolfberry is nourishing Yin and moistening lung, fritillaria thunbergii is moistened the lung and relieve the cough and reduces phlegm, the fruit of Chinese magnoliavine is relieving cough and asthma, climbing groundsel is clearing heat and detoxicating, gynostemma pentaphylla has facilitation to humoral immunity, bush is promoting blood circulation and removing blood stasis, date air making-up and spleen enlivening, nourishing blood and tranquilization, subprostrate sophora removing toxic substances relieve sore throat, adenophora tetraphylla is moistened the lung and relieve the cough, nourishing the stomach to improve the production of body fluid, calyx and receptacle of a persimmon lowering the adverse flow of QI, hawthorn, radish seed stomach strengthening and digestion promoting, hairy euphorbia is clearing heat and detoxicating, dampness removing is antipruritic, Gorgon fruit supplementing the kidney to control the nocturnal, tonifying spleen antidiarrheal, radix fici simplicissimae invigorating the spleen for eliminating dampness, promoting the circulation of qi is reduced phlegm, Japanese cryptotaenia stem and leaf dispelling wind stopping cough, eliminating damp, detoxifying.
Glabrous Sarcandra Herb: latin name Sarcandrae Herba, slightly warm in nature, bitter, pungent, has anti-inflammation, dispelling wind and removing obstruction in the meridians, the effect of blood circulation promoting and dispersing pathogen accumulation, cures mainly the cards such as pneumonia, appendicitis, cellulitis, arthralgia due to wind-dampness, injury from falling down, tumour.
The root of large-flowered skullcap: latin name Scutellariae Radix, bitter, cold in nature, enters the heart, lung, stomach, courage, large intestine channel, has heat-clearing and damp-drying drug, and purging intense heat and detonicating is antiabortive, the effect of hemostasis, the diarrhoea, dysentery, jaundice, the heat that are mainly used in due to damp and hot are drenched; Cough with lung heat, thirsty pharyngalgia, also can be used for fetal movement with fever, and hot malicious fire-evil is invaded the swollen card of sore carbuncle poison of excessive skin.
Great burdock achene: taste is pungent, hardship; Cold in nature, return lung, stomach warp, has dispelling wind and heat from the body, clearing heat and detoxicating promoting eruption, the loose swollen effect of a surname's lung relieve sore throat, cure mainly anemopyretic cold, warm disease from the beginning of; Wind-heat or cough with lung heat, cough up phlegm not smooth; Abscess of throat; Macula is not saturating; At the measles initial stage, rash goes out not smooth and rubella itch; The card such as sore swollen toxin and mumps.
Edible tulip: taste is sweet, micro-pungent, cool in nature, returns liver, the spleen channel, has clearing heat and detoxicatingly, and the effect of reducing phlegm and resolving masses, for the swollen serious case of furuncle of carbuncle, scrofula subcutaneous nodule, scrofula, the cards such as snake bite and insect sting.
Cape jasmine: bitter, cold in nature, enter the heart, lung, three warmers, have the effect of relieving restlessness purging intense heat, soothing liver-qi stagnation, clearing heat and promoting diuresis, cooling blood and hemostasis, be mainly used in the strongly fragrant chest gastral cavity of warm heat disease heat vexed uneasiness, bother not peaceful; Liver depression is not relaxed or Liver Channel has having a dizzy spell of heat, pain in chest and hypochondrium, hot eyes dry throat; Jaundice with damp-heat pathogen; The symptoms such as the abdominal distention of qi depression to blood stasis.
The tuber of dwarf lilyturf: latin name Ophiopogonis Radix, sweet, the micro-hardship of taste, cold nature, enter the heart, lung, stomach warp, have the effect that Yin nourishing and lung moistening, preventing phlegm from forming and stopping coughing, heat-clearing nourish heart, curing mainly the dryness evil impariment of the lung or the lung-dryness syndrome due to yin deficiency has the dry cough phlegm of heat glutinous, the labor hemoptysis of coughing, dry throat nasal cavity dryness, lung carbuncle, dry mouth and throat due to thermal burn stomach-Yin or deficiency of stomach-Yin, the red few tongue of tongue, vague epigastralgia, interior heat is quenched one's thirst, dry feces, the deficiency of the heart-yin and warm disease heat evil are disturbed and the heart-nutriment and the dysphoria and insomnia that causes, the deep red and dry card that waits of tongue.
Sealwort: taste is sweet, property is flat, enters lung, spleen, kidney channel, has nourshing kidney moistening lung, the effect of invigorating the spleen and benefiting qi, for the lung-dryness syndrome due to yin deficiency, dry cough phlegm is few, and many drinks of quenching one's thirst are weakness of the spleen and the stomach, Spleen-Qi Deficiency or deficiency of spleen-YIN, deficiency of kidney essence, soreness and weakness of waist and knees, the cards such as poliosis.
Radix pseudostellariae: sweet, the micro-hardship of taste, property is put down, and enters spleen, lung channel, has air making-up and spleen enlivening, the effect that moistening lung is promoted the production of body fluid, for the few burnout of food of deficiency-weakness of spleen-QI, deficiency of stomach-Yin, the beneficial temper of energy, nourishing stomach-YIN, many for the deficiency syndrome of the lung cough caused by dryness of deficiency of vital energy Tianjin wound and palpitaition egersis, abnormal heat sweat, energy nourishing generate fluid, controls deficiency of vital energy xeropulmonary cough, the cards such as the palpitaition egersis of deficiency of both qi and yin, hidrosis.
The vine of multiflower knotweed: sweet, the micro-hardship of taste, property is flat; The thoughts of returning home, Liver Channel, having can mental-tranquilization, the effect of dispelling wind and removing obstruction in the meridians, cures mainly insomnia and dreamful sleep, deficiency of blood bodily pain, numbness, arthralgia due to wind-dampness, the cards such as wind sore mange.
The fruit of Chinese wolfberry: taste is sweet, property is flat, enters liver, kidney channel, have tonify the liver and kidney, nourish blood enrich blood, benefiting shrewd head, the effect that moistens the lung and relieve the cough, be mainly used in soreness and weakness of waist and knees, dizziness and tinnitus, seminal emission tinnitus, the unconsciously sweat and tire of liver kidney two void, asthenia of essence and blood; The impotence of the insufficiency of the kidney yang, sterile; Dim-sighted and the deficiency of Yin labor of the eyes of deficiency of YIN-essence,impairment of YIN-essence, the deficiency of liver-blood card such as cough.
Fritillaria thunbergii: bitter, cold in nature, enter lung, the heart channel of Hang-Shaoyin, there is clearing heat and eliminating phlegm, the effect of powder detoxifcation, cures mainly cough due to wind-heat evil, lung carbuncle larynx numbness, scrofula, the cards such as sore swollen toxin.
The fruit of Chinese magnoliavine: warm in nature, taste acid, sweet, returns lung, the heart, kidney channel, has convergence astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, the effect of kidney calming, cure mainly the void of coughing for a long time and breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the feeble pulse of losing heart, interior heat is quenched one's thirst, the cards such as palpitation and insomnia.
Climbing groundsel: cold in nature, bitter, returns lung, Liver Channel, has effect clearing heat and detoxicating, improving eyesight dampness removing, have the cards such as carbuncle sore tumefacting virus, cold, fever, red eye, swell pain, dysentery, skin eczema, climbing groundsel has antibacterial activity to staphylococcus aureus, ETEC, shigella dysenteriae.
Gynostemma pentaphylla: cold in nature, taste is sweet, returns lung, spleen, kidney channel, useful gas, calms the nerves, hypotensive effect, for deficiency of vital energy and physically weak, weak breath is weak; Vexed insomnia; High blood pressure, Light-headedness; Virus hepatitis; Tumor in digestive tract; Chronic bronchitis, the polysaccharide that gynostemma pentaphylla is rich in can improve serum hemolysin content, and humoral immunity is had to facilitation, and total saponin(e that gynostemma pentaphylla is rich in can promote lymphocyte transformation, improves the activity of DNA polysaccharide, promotes the synthetic of lymphocyte DNA.
Bush: taste is sweet, become, property is flat, the thoughts of returning home, liver, the spleen channel, have promoting blood circulation, the effect of swelling and pain relieving, cures mainly traumatic injury, the fracture injury of the tissues, stasis swells and ache, through closing dysmenorrhoea, postpartum stasis blocking, chest ventral spine waits card bitterly.
Date: taste is sweet, warm in nature, enter spleen, stomach warp, there is the effect of air making-up and spleen enlivening, nourishing blood and tranquilization, harmonizing yingfen and weifen, the mitigation property of medicine, for weakness of the spleen and the stomach, fatigue and asthenia, anorexia and loose stool, the card such as insufficiency of vital energy and blood, has a headache and fever, sweating hot blast.
Subprostrate sophora: bitter, cold in nature, enter the heart, lung, large intestine channel, there is removing toxic substances relieve sore throat, clearing heat and promoting diuresis, the effect that desinsection is anticancer, for abscess of throat, the gum dentalgia that swells, cough with lung heat, dysentery, jaundice, the cards such as the swollen favus of the scalp of heat.
Adenophora tetraphylla: sweet, the micro-hardship of taste, cold nature, enters lung, stomach warp, moistens the lung and relieve the cough, and the effect of nourishing the stomach to improve the production of body fluid, is mainly used in the few phlegm of the lung-dryness syndrome due to yin deficiency, dry cough, the labor phlegm blood of coughing, the cards such as deficiency of stomach-Yin, mouthfeel pharynx are dry, constipation, the red few tongue of tongue.
The calyx and receptacle of a persimmon: bitter, flat, return stomach warp, there is the effect of lowering the adverse flow of QI, cure mainly hiccup; Gas; The cards such as gastric disorder causing nausea.
Taste acid, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel, and for food digesting stomach fortifying, the promoting the circulation of qi stasis of blood of fall apart, is mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, hawthorn is the staple for the treatment of indigestion, hawthorn can increase the secretion of peptic digest enzyme, promotes to digest; Shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc. are had to obvious inhibitory action.
Radish seed: property is flat, and taste is pungent, sweet, returns lung, spleen, stomach warp, has the de-swelling of helping digestion, the effect of lowering the adverse-rising QI to resolve phlegm, cures mainly retention of food and drink, abdominal distention, constipation, the stagnant dysentery, phlegm of rushing down is stopped up the card such as breath with cough.
Hairy euphorbia: mildly bitter flavor, micro-acid, cool in nature, have clearing heat and detoxicating, the effect that dampness removing is antipruritic, for bacillary dysentery, amoebic dysentery, enteritis, enteron aisle trichomonad, indigestion, bronchitis, pyelonephritis; The cards such as eczema, dermatitis, pruitus are controlled in external application.
Gorgon fruit: taste is sweet, puckery, property is flat.Return spleen, kidney channel.There is supplementing the kidney to control the nocturnal, tonifying spleen antidiarrheal, clearing damp is the function of band only, cures mainly emission, splenasthenic diarrhea, insufficiency of the spleen gonorrhoea, is with inferior card.
Sting five power: latin name Acanthopanacis Senticosi Radix et Rhizomaseu Caulis, taste is pungent, bitter, micro-sweet, warm in nature, enter spleen, kidney, the heart channel of Hang-Shaoyin, have and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, the effect of dispelling rheumatism, soft for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence, be slow in action, the card such as body void is thin and weak, traumatic injury, fracture, oedema, beriberi, uncontrolled urination are itched.
Radix fici simplicissimae: sweet, tepor, has invigorating the spleen for eliminating dampness, and promoting the circulation of qi is reduced phlegm, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, cures mainly pulmonary tuberculosis cough, chronic bronchitis, rheumatic arthritis, waist has a pain in the leg, insufficiency of the spleen edema, the after being ill card such as night sweat.
Japanese cryptotaenia stem and leaf: taste is pungent, hardship; Property is put down, and has dispelling wind stopping cough; Eliminating damp, detoxifying; The effect of blood-activating analgetic, cures mainly pneumonia, pulmonary abscess, and gonorrhoea, hernia, acute toothache, ulcer malignant boil is swollen, herpes zoster, the cards such as pruitus.
In described Chinese medicine immune formulation, the weight portion of each bulk drug is respectively: Glabrous Sarcandra Herb 25 weight portion～35 weight portions, the root of large-flowered skullcap 45 weight portion～55 weight portions, great burdock achene 25 weight portion～35 weight portions, edible tulip 35 weight portion～45 weight portions, cape jasmine 45 weight portion～55 weight portions, the tubers of dwarf lilyturf 55 weight portion～65 weight portion, sealwort 45 weight portion～55 weight portions, radix pseudostellariae 75 weight portion～85 weight portions, the vine of multiflower knotweed 35 weight portion～45 weight portions, the fruit of Chinese wolfberry 55 weight portion～65 weight portions, fritillaria thunbergii 20 weight portion～30 weight portions, the fruit of Chinese magnoliavine 25 weight portion～35 weight portions, climbing groundsel 20 weight portion～30 weight portions, gynostemma pentaphylla 45 weight portion～55 weight portions, bush 20 weight portion～30 weight portions, date 35 weight portion～45 weight portions, subprostrate sophora 25 weight portion～35 weight portions, adenophora tetraphylla 45 weight portion～55 weight portions, the calyx and receptacle of a persimmon 20 weight portion～30 weight portions, hawthorn 25 weight portion～35 weight portions, radish seed 20 weight portion～30 weight portions, hairy euphorbia 25 weight portion～35 weight portions, Gorgon fruit 35 weight portion～45 weight portions, wilsonii 30 weight portion～40 weight portions, radix fici simplicissimae 30 weight portion～40 weight portions and Japanese cryptotaenia stem and leaf 20 weight portion～30 weight portions.
Further preferably, in described Chinese medicine immune formulation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 28 weight portion～32 weight portions, the root of large-flowered skullcap 48 weight portion～52 weight portions, great burdock achene 28 weight portion～32 weight portions, edible tulip 38 weight portion～42 weight portions, cape jasmine 48 weight portion～52 weight portions, the tubers of dwarf lilyturf 58 weight portion～62 weight portion, sealwort 48 weight portion～52 weight portions, radix pseudostellariae 78 weight portion～82 weight portions, the vine of multiflower knotweed 38 weight portion～42 weight portions, the fruit of Chinese wolfberry 58 weight portion～62 weight portions, fritillaria thunbergii 23 weight portion～27 weight portions, the fruit of Chinese magnoliavine 28 weight portion～32 weight portions, climbing groundsel 23 weight portion～27 weight portions, gynostemma pentaphylla 48 weight portion～52 weight portions, bush 23 weight portion～27 weight portions, date 38 weight portion～42 weight portions, subprostrate sophora 28 weight portion～32 weight portions, adenophora tetraphylla 48 weight portion～52 weight portions, the calyx and receptacle of a persimmon 23 weight portion～27 weight portions, hawthorn 28 weight portion～32 weight portions, radish seed 23 weight portion～27 weight portions, hairy euphorbia 28 weight portion～32 weight portions, Gorgon fruit 38 weight portion～42 weight portions, wilsonii 33 weight portion～37 weight portions, radix fici simplicissimae 33 weight portion～37 weight portions and Japanese cryptotaenia stem and leaf 23 weight portion～27 weight portions.
Further preferred, in described Chinese medicine immune formulation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 30 weight portions, the root of large-flowered skullcap 50 weight portions, great burdock achene 30 weight portions, edible tulip 40 weight portions, cape jasmine 50 weight portions, the tubers of dwarf lilyturf 60 weight portion, sealwort 50 weight portions, radix pseudostellariae 80 weight portions, the vine of multiflower knotweed 40 weight portions, the fruit of Chinese wolfberry 60 weight portions, fritillaria thunbergii 25 weight portions, the fruit of Chinese magnoliavine 30 weight portions, climbing groundsel 25 weight portions, gynostemma pentaphylla 50 weight portions, bush 25 weight portions, date 40 weight portions, subprostrate sophora 30 weight portions, adenophora tetraphylla 50 weight portions, the calyx and receptacle of a persimmon 25 weight portions, hawthorn 30 weight portions, radish seed 25 weight portions, hairy euphorbia 30 weight portions, Gorgon fruit 40 weight portions, wilsonii 35 weight portions, radix fici simplicissimae 35 weight portions and Japanese cryptotaenia stem and leaf 25 weight portions.
The first step, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, gynostemma pentaphylla, date, adenophora tetraphylla, Gorgon fruit and wilsonii are mixed in proportion, getting mixture 100g packs in percolator, white wine 600g～the 800g that adds 50 ℃～55 ℃, under the condition of 25 ℃～35 ℃, soak 20 hours～30 hours, regulate percolator valve, white wine liquid is slowly oozed, and the speed of oozing is 2～4mL per minute, collects drip, obtain the percolate of 700mL～1L, concentrated, remove white wine, dry, pulverize, obtain the first dried powder;
Second step, mixes remaining component in proportion, gets 100g mixture, the water that adds 500g～800g, boils 3～4 hours, filters, obtain the first filtrate, filter residue adds the water of 200g～300g again, again boils 1～2 hour, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder;
The 3rd step, mixes the first dried powder and the second dried powder, obtains Chinese medicine immune formulation powder.
Chinese medicine immune formulation provided by the invention can be admixed in feed for chicken and take, or is dissolved in water and gavages to chicken.
It is a kind of for preventing the feed of infectious bronchitis of chicken that the present invention also provides, and its raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamin(e) supplement and for preventing the Chinese medicine immune formulation powder feed addictive of infectious bronchitis of chicken.
Further, described feed only consists of above-mentioned raw materials.
Wherein, in described feed, the weight portion of each material composition is respectively corn 90 weight portion～110 weight portions, dregs of beans 30 weight portion～50 weight portions, salt 2 weight portion～4 weight portions, fish meal 8 weight portion～12 weight portions, bone meal 3 weight portion～5 weight portions, trace mineral supplement 2 weight portion～4 weight portions, amino acid additive 2 weight portion～4 weight portions, vitamin(e) supplement 2 weight portion～4 weight portions and Chinese medicine immune formulation powder feed addictive 15 weight portion～20 weight portions.
Further preferably, in described feed, the weight portion of each material composition is respectively corn 100 weight portions, dregs of beans 40 weight portions, salt 3 weight portions, fish meal 10 weight portions, bone meal 4 weight portions, trace mineral supplement 3 weight portions, amino acid additive 3 weight portions, vitamin(e) supplement 3 weight portions and Chinese medicine immune formulation powder feed addictive 18 weight portions.
Trace mineral supplement can be the trace mineral supplement of various routines, can use simple acylate, as ironic citrate, also can use trace element and amino-acid chelate, as amino acid iron, the trace element adding mainly contains iron, zinc, copper, manganese, iodine, cobalt, selenium, molybdenum, also can use composite trace element premix, the Great Britain and America who provides as Beijing You Libao biotechnology Co., Ltd you.
Amino acid additive comprises the various conventional amino acid such as serine, glutamic acid, glycine, isoleucine, leucine, alanine, proline, also can adopt amino acid premix, the composite aminophenol powder that as above sea cowry energy Chemical Co., Ltd. produces.
Vitamin(e) supplement comprises the various conventional vitamins such as riboflavin, vitamin C, vitamin E, vitamin A, Cobastab, also can adopt vitamin premix, as plain in the excellent dimension that Beijing You Libao Bioisystech Co., Ltd produces.
The present invention also provides the preparation method of above-mentioned feed, is specially:
The first step, prepares described Chinese medicine immune formulation powder feed addictive according to the method described above;
Second step, puts into fodder mixing machine together with the described Chinese medicine immune formulation powder feed addictive that other raw material components in feedstuff and the first step are obtained, and continuous uniform stirred after 1～3 hour, put into pulverizer and pulverized, and obtained feed.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine immune formulation 1
By the 60g tuber of dwarf lilyturf, sealwort 50g, radix pseudostellariae 80g, vine of multiflower knotweed 40g, fruit of Chinese wolfberry 60g, gynostemma pentaphylla 50g, date 40g, adenophora tetraphylla 50g, Gorgon fruit 40g and wilsonii 35g mix in proportion, get mixture 100g and pack in percolator, add the white wine 700g of 50 ℃, under the condition of 30 ℃, soak 25 hours, regulate percolator valve, white wine liquid is slowly oozed, the speed of oozing is 3mL per minute, collects drip, obtains the percolate of 800mL, concentrated, remove white wine, dry, pulverize, obtain the first dried powder, by Glabrous Sarcandra Herb 30g, root of large-flowered skullcap 50g, great burdock achene 30g, edible tulip 40g, cape jasmine 50g, fritillaria thunbergii 25g, fruit of Chinese magnoliavine 30g, climbing groundsel 25g, bush 25g, subprostrate sophora 30g, calyx and receptacle of a persimmon 25g, hawthorn 30g, radish seed 25g, hairy euphorbia 30g, radix fici simplicissimae 35g and Japanese cryptotaenia stem and leaf 25g mix, and get 100g mixture, add the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boils 2 hours, filters, obtain the second filtrate, the first filtrate and the second filtrate are mixed, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder, the first dried powder and the second dried powder are mixed, obtain Chinese medicine immune formulation 1.
Embodiment 2 Chinese medicine immune formulations 2
By the 58g tuber of dwarf lilyturf, sealwort 48g, radix pseudostellariae 78g, vine of multiflower knotweed 38g, fruit of Chinese wolfberry 58g, gynostemma pentaphylla 48g, date 38g, adenophora tetraphylla 48g, Gorgon fruit 38g and wilsonii 33g mix in proportion, get mixture 100g and pack in percolator, add the white wine 700g of 50 ℃, under the condition of 30 ℃, soak 25 hours, regulate percolator valve, white wine liquid is slowly oozed, the speed of oozing is 3mL per minute, collects drip, obtains the percolate of 800mL, concentrated, remove white wine, dry, pulverize, obtain the first dried powder, by Glabrous Sarcandra Herb 28g, root of large-flowered skullcap 48g, great burdock achene 28g, edible tulip 38g, cape jasmine 48g, fritillaria thunbergii 23g, fruit of Chinese magnoliavine 28g, climbing groundsel 23g, bush 23g, subprostrate sophora 28g, calyx and receptacle of a persimmon 23g, hawthorn 28g, radish seed 23g, hairy euphorbia 28g, radix fici simplicissimae 33g and Japanese cryptotaenia stem and leaf 23g mix, and get 100g mixture, add the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boils 2 hours, filters, obtain the second filtrate, the first filtrate and the second filtrate are mixed, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder, the first dried powder and the second dried powder are mixed, obtain Chinese medicine immune formulation 2.
Embodiment 3 Chinese medicine immune formulations 3
By the 62g tuber of dwarf lilyturf, sealwort 52g, radix pseudostellariae 82g, vine of multiflower knotweed 42g, fruit of Chinese wolfberry 62g, gynostemma pentaphylla 52g, date 42g, adenophora tetraphylla 52g, Gorgon fruit 42g and wilsonii 37g mix in proportion, get mixture 100g and pack in percolator, add the white wine 700g of 50 ℃, under the condition of 30 ℃, soak 25 hours, regulate percolator valve, white wine liquid is slowly oozed, the speed of oozing is 3mL per minute, collects drip, obtains the percolate of 800mL, concentrated, remove white wine, dry, pulverize, obtain the first dried powder, by Glabrous Sarcandra Herb 32g, root of large-flowered skullcap 52g, great burdock achene 32g, edible tulip 42g, cape jasmine 52g, fritillaria thunbergii 27g, fruit of Chinese magnoliavine 32g, climbing groundsel 27g, bush 27g, subprostrate sophora 32g, calyx and receptacle of a persimmon 27g, hawthorn 32g, radish seed 27g, hairy euphorbia 32g, radix fici simplicissimae 37g and Japanese cryptotaenia stem and leaf 27g mix, and get 100g mixture, add the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boils 2 hours, filters, obtain the second filtrate, the first filtrate and the second filtrate are mixed, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder, the first dried powder and the second dried powder are mixed, obtain Chinese medicine immune formulation 3.
Embodiment 4 toxicological experiments
Acute toxicity testing
Select 20 of Kunming mouses, female half and half, body weight (20+2) g, by Qingdao City's Experimental Animal Center, provided, the Chinese medicine immune formulation of embodiment 1 preparation is dissolved in water, obtain the solution that crude drug concentration is 1g/ml, gavage mouse, through preliminary experiment, fail to detect the LD of oral administration
50, therefore survey its maximal tolerance dose, administration volume with 1.4ml/10g body weight, gavage 2 times/d, interval 6h, give observation post administration 7d, record animal dead and toxicity symptom, when experiment finishes, all animals is processed, dissect, visually observe each main organs lesion tissue situation, gavage for 2 times after 140g crude drug/kg, animal activity, feed water inlet does not show any abnormalities, observe 7d animal dead, gross necropsy has no the obviously abnormal of main organs tissue, therefore, the maximum dosage-feeding of Chinese herbal granules is > 140g crude drug/kg, this dosage is equivalent to 70 times of maximum oral dose 2g crude drug/kg clinical adult (by 60kg) every day.
Long term toxicity test
Select 40 male SD rats, weight (180 ± 20) g, by Qingdao City's Experimental Animal Center, provided, be divided at random 2 groups, blank group and Chinese drug-treated group, every group 20, blank group gives distilled water, the Chinese medicine immune formulation of embodiment 1 preparation is dissolved in water, obtain the solution that crude drug concentration is 1g/ml, gavage rat, the amount of gavaging is 50g crude drug/kg, on every Mondays to gastric infusion 1 time in morning Saturday, continuous 180d, administration volume is 2mL/100g body weight, observe rat general state every day before administration and during administration, sign, food ration, drinking-water and ight soil situation.During administration 90d, after last administration 24h, each group extracts 6, male and female half and half; During 180d, after last administration 24h, each group extracts 6, male and female half and half; After drug withdrawal, each group of 30d extracts 6, male and female half and half, with urethane, anaesthetize, from abdominal aortic, get blood, each group is all killed and is got animal, checks hematology and blood parameters, gets after blood, amass wealth by heavy taxation at once core, the internal organs such as liver,kidney,spleen, lung, adrenal gland, thyroid gland, thymus gland, testis, ovary, uterus, brain, prostate weigh, according to weight calculator official weight coefficient and make pathological examination.
On inspection, during successive administration, the activity of animal, body weight, food ration, stool and hair luster degree no abnormality seen, it is dead that animal has no, naked eyes have no obvious pathology, each organizes the inspection of rat peripheral hemogram all in normal range (NR), and physiochemical indice is all in normal range (NR), and Chinese drug-treated group Rats Organs and Tissues coefficient is compared and be there is no significant difference with blank group.
Embodiment 5 feeds 1
Together with Chinese medicine immune formulation 1.8kg prepared by corn 10kg, dregs of beans 4kg, salt 0.3kg, fish meal 0.1kg, bone meal 0.4kg, trace mineral supplement Great Britain and America that (Beijing You Libao biotechnology Co., Ltd provides) 0.3kg, amino acid additive composite aminophenol powder (above sea cowry energy Chemical Co., Ltd. produces) 0.3kg, excellent dimension element (production of Beijing You Libao Bioisystech Co., Ltd) 0.3kg of vitamin(e) supplement and embodiment 1, put into fodder mixing machine, continuous uniform stirred after 3 hours, put into pulverizer and pulverize, obtain feed 1.
Comparative example 1 feed 2
Corn 10kg, dregs of beans 4kg, salt 0.3kg, fish meal 0.1kg, bone meal 0.4kg, trace mineral supplement Great Britain and America that (Beijing You Libao biotechnology Co., Ltd provides) 0.3kg, amino acid additive composite aminophenol powder (above sea cowry energy Chemical Co., Ltd. produces) 0.3kg, the excellent dimension element of vitamin(e) supplement (production of Beijing You Libao Bioisystech Co., Ltd) 0.3kg are put into fodder mixing machine together, continuous uniform stirred after 3 hours, put into pulverizer and pulverize, obtain feed 2.
Embodiment 6 zooperies
Animal used as test
Select 400 of the healthy SPF chickens of 7 ages in days, by Qingdao, Nanjing brocade animal used as test Co., Ltd provides, and without IBV epidemic prevention, is divided at random 4 groups, 100 every group.
Normal healthy controls group: do not attack poison, do not feed any medicine, isolated rearing, feeding corn feed.
Attack malicious control group: attack after poison, do not feed any medicine, isolated rearing, feeding corn feed.
Prevent 1 group: attack the feed 1 that poison starts feeding embodiment 5 preparations for first 3 days.
Prevent 2 groups: attack the feed 2 that poison starts 1 preparation of feeding comparative example for first 3 days.
Experimental drug
The feed 2 of the feed 1 of embodiment 5 preparations and comparative example 1 preparation.
IBV
Attacking poison provides with IBV M41 velogen strain ，You China Veterinary Drugs Supervisory Inst., during use, virus is diluted by tracheae inoculation test chicken 0.2ml/ only at 1: 10.
Symptom classification and curative effect judging standard
Through trial test, determine that the infective dose of IBV-M41 strain kind poison is that every plumage 0.2mL carries out collunarium inoculation.When attacking the most chickens morbidity of malicious control group, each group chicken is carried out to clinical symptoms and score, and test chicken is cutd open to inspection, cut open and examine symptom and score, calculate each group result of scoring, according to curative effect judging standard, conclude.Clinical symptoms classification, cut open inspection symptom classification and curative effect determinate standard specific as follows:
Clinical symptoms classification
One-level (0 minute): the chicken state of mind is good, diet is wanted, activity is all normal.
Secondary (1 minute): be discontinuity cough, accidental nasal cavity has mucus, gets rid of head, and food effect is little, and walking is normal.
Three grades (2 minutes): expiratory dyspnea, tracheae has rale, and spirit is depressed, and feather is contrary vertical, peels off slow-witted vertical, and appetite declines or does not eat.
Level Four (3 minutes): expiratory dyspnea, death by suffocation.
Cut open the classification of inspection symptom
One-level (0 minute): without obviously pathological change.
Secondary (1 minute): have mucus secretion in nasal cavity, have thin mucus secretion in tracheae and bronchus.The micro-muddiness of air bag.
Three grades (2 minutes): in tracheae hypomere and bronchus, have the secretion of more thickness, have no hemorrhage, air bag thickens.
Level Four (3 minutes): have yellow cheesy exudate in tracheae hypomere and bronchus.Some tracheae hypomeres and bronchus place have ring-type hemorrhage.Air bag thickens.
Curative effect determinate standard
Effective: refer to attack the rear 48h of poison, prevention group is compared with attacking malicious control group, and main clinic symptoms, the pathological change of morbidity chicken obviously improve, i.e. 60% < therapeutic index < 100%.
Effective: refer to attack the rear 48h of poison, prevention group is compared with attacking malicious control group, and main clinic symptoms, the pathological change of morbidity chicken make moderate progress, i.e. 30% < therapeutic index < 60%.
Invalid: refer to attack the rear 48h of poison, prevention group is compared with attacking malicious control group, and main clinic symptoms, the pathological change of morbidity chicken are not improved or add to some extent severe one, and therapeutic index < 30%.
Note: therapeutic index=(attacking score-prevention of malicious control group group scores) ÷ attack malicious control group score * 100%.
Data processing and analysis
Each is organized data and all uses mean soil standard deviation
represent, each is organized mean and does test of normality and duplicate measurements homogeneity test of variance, younger check between organizing with one-way analysis of variance), P < 0.05 is for differing significantly, and P < 0.01 is for differing highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Result
Attacking malicious control group most of chicken after attacking malicious 48h and occur significantly cough, there is the symptoms such as rale, expiratory dyspnea in part chicken, and sick chicken spirit is depressed, poor appetite, dead chicken is cutd open to inspection, occur infectious bronchitis of chicken typical case pathological change, illustrate and attack poison success.
Chinese medicine immune formulation of the present invention to the preventive effect of infectious bronchitis of chicken in Table 1.
The preventive effect of table 1 Chinese medicine immune formulation to infectious bronchitis of chicken
As can be seen from Table 1, adopt the prevention group incidence of disease of Chinese medicine immune formulation of the present invention to be significantly less than the prevention group of attacking malicious control group and not adding Chinese medicine immune formulation of the present invention, illustrate that the preventive effect of this Chinese medicine immune formulation is remarkable.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (6)
1. for preventing a feed for infectious bronchitis of chicken, it is characterized in that: raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamin(e) supplement and for preventing the Chinese medicine immune formulation powder feed addictive of infectious bronchitis of chicken.
2. feed as claimed in claim 1, is characterized in that: the weight portion of each material composition is respectively corn 90 weight portion～110 weight portions, dregs of beans 30 weight portion～50 weight portions, salt 2 weight portion～4 weight portions, fish meal 8 weight portion～12 weight portions, bone meal 3 weight portion～5 weight portions, trace mineral supplement 2 weight portion～4 weight portions, amino acid additive 2 weight portion～4 weight portions, vitamin(e) supplement 2 weight portion～4 weight portions and Chinese medicine immune formulation powder feed addictive 15 weight portion～20 weight portions.
3. feed as claimed in claim 1 or 2, is characterized in that: the bulk drug of described Chinese medicine immune formulation powder feed addictive comprises Glabrous Sarcandra Herb, the root of large-flowered skullcap, great burdock achene, edible tulip, cape jasmine, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, fritillaria thunbergii, the fruit of Chinese magnoliavine, climbing groundsel, gynostemma pentaphylla, bush, date, subprostrate sophora, adenophora tetraphylla, the calyx and receptacle of a persimmon, hawthorn, radish seed, hairy euphorbia, Gorgon fruit, wilsonii, radix fici simplicissimae and Japanese cryptotaenia stem and leaf.
4. the feed as described in claims 1 to 3, is characterized in that: in described Chinese medicine immune formulation powder feed addictive, the weight portion of each bulk drug is respectively: Glabrous Sarcandra Herb 25 weight portion～35 weight portions, the root of large-flowered skullcap 45 weight portion～55 weight portions, great burdock achene 25 weight portion～35 weight portions, edible tulip 35 weight portion～45 weight portions, cape jasmine 45 weight portion～55 weight portions, the tubers of dwarf lilyturf 55 weight portion～65 weight portion, sealwort 45 weight portion～55 weight portions, radix pseudostellariae 75 weight portion～85 weight portions, the vine of multiflower knotweed 35 weight portion～45 weight portions, the fruit of Chinese wolfberry 55 weight portion～65 weight portions, fritillaria thunbergii 20 weight portion～30 weight portions, the fruit of Chinese magnoliavine 25 weight portion～35 weight portions, climbing groundsel 20 weight portion～30 weight portions, gynostemma pentaphylla 45 weight portion～55 weight portions, bush 20 weight portion～30 weight portions, date 35 weight portion～45 weight portions, subprostrate sophora 25 weight portion～35 weight portions, adenophora tetraphylla 45 weight portion～55 weight portions, the calyx and receptacle of a persimmon 20 weight portion～30 weight portions, hawthorn 25 weight portion～35 weight portions, radish seed 20 weight portion～30 weight portions, hairy euphorbia 25 weight portion～35 weight portions, Gorgon fruit 35 weight portion～45 weight portions, wilsonii 30 weight portion～40 weight portions, radix fici simplicissimae 30 weight portion～40 weight portions and Japanese cryptotaenia stem and leaf 20 weight portion～30 weight portions.
5. the feed described in claim 1 to 4, is characterized in that: the preparation method of described Chinese medicine immune formulation powder feed addictive is specially,
The first step, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, gynostemma pentaphylla, date, adenophora tetraphylla, Gorgon fruit and wilsonii are mixed in proportion, getting mixture 100g packs in percolator, white wine 600g～the 800g that adds 50 ℃～55 ℃, under the condition of 25 ℃～35 ℃, soak 20 hours～30 hours, regulate percolator valve, white wine liquid is slowly oozed, and the speed of oozing is 2～4mL per minute, collects drip, obtain the percolate of 700mL～1L, concentrated, remove white wine, dry, pulverize, obtain the first dried powder;
Second step, mixes remaining component in proportion, gets 100g mixture, the water that adds 500g～800g, boils 3～4 hours, filters, obtain the first filtrate, filter residue adds the water of 200g～300g again, again boils 1～2 hour, filter, obtain the second filtrate, the first filtrate and the second filtrate are mixed, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder;
The 3rd step, mixes the first dried powder and the second dried powder, obtains Chinese medicine immune formulation.
6. the preparation method of feed described in claim 1 to 5, is characterized in that:
The first step, prepares described Chinese medicine immune formulation powder feed addictive according to method described in claim 5;
Second step, puts into fodder mixing machine together with the described Chinese medicine immune formulation powder feed addictive that other raw material components in feedstuff and the first step are obtained, and continuous uniform stirred after 1～3 hour, put into pulverizer and pulverized, and obtained feed.
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| CN104222632A (en) * | 2014-09-10 | 2014-12-24 | 青岛华仁技术孵化器有限公司 | Feed for preventing coccidiosis of rabbits |
| CN104222631A (en) * | 2014-09-10 | 2014-12-24 | 青岛华仁技术孵化器有限公司 | Feed for treating coccidiosis of rabbits |
| CN105053630A (en) * | 2015-07-31 | 2015-11-18 | 张翔 | Feed containing Chinese medicinal additive for controlling goose laryngotracheitis |
| CN105519812A (en) * | 2016-01-01 | 2016-04-27 | 闫冷 | Chick infectious broncheitis treatment feed additive |
| CN106306533A (en) * | 2016-08-20 | 2017-01-11 | 丁永军 | Traditional Chinese medicine feed for preventing and treating infectious bronchitis and preparation method thereof |
| CN107279571A (en) * | 2017-07-20 | 2017-10-24 | 无为县青松养殖有限公司 | A kind of laying hen disease-resistant feed |
| CN107279577A (en) * | 2017-07-25 | 2017-10-24 | 安徽华米生物科技有限公司 | It is a kind of to be used to prevent and treat feed of infectious bronchitis of chicken and preparation method thereof |
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