CN103598460B - For preventing the feed of infectious bronchitis of chicken - Google Patents
For preventing the feed of infectious bronchitis of chicken Download PDFInfo
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Abstract
The invention provides a kind of for preventing the feed of infectious bronchitis of chicken, it is characterized in that: raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamine supplement and for preventing the Traditional Chinese medicine immune preparation powder feed addictive of infectious bronchitis of chicken.This feed has significant effect in prevention infectious bronchitis of chicken, and has nontoxic, the advantage of resistance, drug residue free.
Description
Technical field
The present invention relates to technical field of Chinese medicine, particularly relating to a kind of for preventing the feed of infectious bronchitis of chicken.
Background technology
Infectious bronchitis of chicken (Infectious Bronchitis, IB) be by IBV (Infectious Bronchitis Virus, IBV) the acute high degree in contact sexually transmitted disease of the one caused, infected chicken is because of growth retardation, feed consumption increases, lay eggs and egg matter declines, death rate increases, and causes tremendous economic to lose to poultry husbandry.In order to the generation of this disease of prevention and corntrol effectively, now adopt vaccine immunity and western medicine more, because IBV strain has the feature of highly easily variation and many serotype, and make immunity inoculation complicated, be difficult to prevent and treat.At present, China mainly prevents and treats infectious bronchitis of chicken with Western medicine, but mainly excretes via renal metabolism due to Western medicine, and the kidney damage caused by this disease makes medicine put aside in a large number in vivo, not only to the unsatisfactory curative effect of this disease, but also easily produce a toxic reaction to a drug.
Chinese medicine carrying out comprehensively regulating to animal organism physiological function, improve body immunity, premunition and antiviral etc. in there is distinctive feature, can effectively prevention and control and treat this disease.Chinese veterinarian think infective bronchitis mainly heat poison, wet poison, epidemic disease malicious in accumulate, cause sputum to block tracheae, cause coughing and breathe heavily, stream nose liquid, cough to breathe heavily and injure healthy tendency, cause the failure of the kidney in receiving air, Wei Yang does not fill, and lower void is contained, suffer from a deficiency of the kidney and can not normally to evaporate water liquid, therefore shape is trembled with fear, limb is cold, and ight soil is abnormal.
The dirty pathology and disease mechanism of the Clinical symptoms of infectious bronchitis of chicken and traditional Chinese veterinary medicine lung, spleen, kidney three is closely related, theoretical according to Chinese veterinarian, infectious bronchitis of chicken is plague poison evil criminal lung, phlegm is turbid to be jammed, causing lung to lose a surname respectful, qi stagnation hemagglutination, body fluid loses caused by the spreading, its disease basic at lung, and Syndrome Differentiation of Traditional Chinese Medicine is in the majority with affection of exogenous wind-heat, minority is syndrome of superficies cold and interior heat, all belongs to heat and to defend point or disease involving weifen and qifen.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for preventing Traditional Chinese medicine immune preparation and the feed of infectious bronchitis of chicken, and it has significant effect in prevention infectious bronchitis of chicken, and has nontoxic, the advantage of resistance, drug residue free.
For solving the problems of the technologies described above, the invention provides a kind of for preventing the Traditional Chinese medicine immune preparation of infectious bronchitis of chicken, its bulk drug comprises Glabrous Sarcandra Herb, the root of large-flowered skullcap, great burdock achene, edible tulip, cape jasmine, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, fritillaria thunbergii, the fruit of Chinese magnoliavine, climbing groundsel, gynostemma pentaphylla, bush, date, subprostrate sophora, adenophora tetraphylla, the calyx and receptacle of a persimmon, hawthorn, radish seed, hairy euphorbia, Gorgon fruit, wilsonii, radix fici simplicissimae and Japanese cryptotaenia stem and leaf.
Wherein, in described Traditional Chinese medicine immune preparation, the weight portion of each bulk drug is respectively: Glabrous Sarcandra Herb 25 weight portion ~ 35 weight portion, the root of large-flowered skullcap 45 weight portion ~ 55 weight portion, great burdock achene 25 weight portion ~ 35 weight portion, edible tulip 35 weight portion ~ 45 weight portion, cape jasmine 45 weight portion ~ 55 weight portion, the tuber of dwarf lilyturf 55 weight portion ~ 65 weight portion, sealwort 45 weight portion ~ 55 weight portion, radix pseudostellariae 75 weight portion ~ 85 weight portion, the vine of multiflower knotweed 35 weight portion ~ 45 weight portion, the fruit of Chinese wolfberry 55 weight portion ~ 65 weight portion, fritillaria thunbergii 20 weight portion ~ 30 weight portion, the fruit of Chinese magnoliavine 25 weight portion ~ 35 weight portion, climbing groundsel 20 weight portion ~ 30 weight portion, gynostemma pentaphylla 45 weight portion ~ 55 weight portion, bush 20 weight portion ~ 30 weight portion, date 35 weight portion ~ 45 weight portion, subprostrate sophora 25 weight portion ~ 35 weight portion, adenophora tetraphylla 45 weight portion ~ 55 weight portion, the calyx and receptacle of a persimmon 20 weight portion ~ 30 weight portion, hawthorn 25 weight portion ~ 35 weight portion, radish seed 20 weight portion ~ 30 weight portion, hairy euphorbia 25 weight portion ~ 35 weight portion, Gorgon fruit 35 weight portion ~ 45 weight portion, wilsonii 30 weight portion ~ 40 weight portion, radix fici simplicissimae 30 weight portion ~ 40 weight portion and Japanese cryptotaenia stem and leaf 20 weight portion ~ 30 weight portion.
Wherein, in described Traditional Chinese medicine immune preparation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 28 weight portion ~ 32 weight portion, the root of large-flowered skullcap 48 weight portion ~ 52 weight portion, great burdock achene 28 weight portion ~ 32 weight portion, edible tulip 38 weight portion ~ 42 weight portion, cape jasmine 48 weight portion ~ 52 weight portion, the tuber of dwarf lilyturf 58 weight portion ~ 62 weight portion, sealwort 48 weight portion ~ 52 weight portion, radix pseudostellariae 78 weight portion ~ 82 weight portion, the vine of multiflower knotweed 38 weight portion ~ 42 weight portion, the fruit of Chinese wolfberry 58 weight portion ~ 62 weight portion, fritillaria thunbergii 23 weight portion ~ 27 weight portion, the fruit of Chinese magnoliavine 28 weight portion ~ 32 weight portion, climbing groundsel 23 weight portion ~ 27 weight portion, gynostemma pentaphylla 48 weight portion ~ 52 weight portion, bush 23 weight portion ~ 27 weight portion, date 38 weight portion ~ 42 weight portion, subprostrate sophora 28 weight portion ~ 32 weight portion, adenophora tetraphylla 48 weight portion ~ 52 weight portion, the calyx and receptacle of a persimmon 23 weight portion ~ 27 weight portion, hawthorn 28 weight portion ~ 32 weight portion, radish seed 23 weight portion ~ 27 weight portion, hairy euphorbia 28 weight portion ~ 32 weight portion, Gorgon fruit 38 weight portion ~ 42 weight portion, wilsonii 33 weight portion ~ 37 weight portion, radix fici simplicissimae 33 weight portion ~ 37 weight portion and Japanese cryptotaenia stem and leaf 23 weight portion ~ 27 weight portion.
Wherein, in described Traditional Chinese medicine immune preparation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 30 weight portion, the root of large-flowered skullcap 50 weight portion, great burdock achene 30 weight portion, edible tulip 40 weight portion, cape jasmine 50 weight portion, the tuber of dwarf lilyturf 60 weight portion, sealwort 50 weight portion, radix pseudostellariae 80 weight portion, the vine of multiflower knotweed 40 weight portion, the fruit of Chinese wolfberry 60 weight portion, fritillaria thunbergii 25 weight portion, the fruit of Chinese magnoliavine 30 weight portion, climbing groundsel 25 weight portion, gynostemma pentaphylla 50 weight portion, bush 25 weight portion, date 40 weight portion, subprostrate sophora 30 weight portion, adenophora tetraphylla 50 weight portion, the calyx and receptacle of a persimmon 25 weight portion, hawthorn 30 weight portion, radish seed 25 weight portion, hairy euphorbia 30 weight portion, Gorgon fruit 40 weight portion, wilsonii 35 weight portion, radix fici simplicissimae 35 weight portion and Japanese cryptotaenia stem and leaf 25 weight portion.
Present invention also offers the preparation method of above-mentioned Traditional Chinese medicine immune preparation, be specially:
The first step, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, gynostemma pentaphylla, date, adenophora tetraphylla, Gorgon fruit and wilsonii are mixed in proportion, getting mixture 100g loads in percolator, add the white wine 600g ~ 800g of 50 DEG C ~ 55 DEG C, soak 20 hours ~ 30 hours under the condition of 25 DEG C ~ 35 DEG C, regulate percolator valve, white wine liquid is slowly oozed, and the speed of oozing is 2 ~ 4mL per minute, collects drip, obtain the percolate of 700mL ~ 1L, concentrated, removing white wine, dry, pulverize, obtain the first dried powder;
Second step, mixes in proportion by remaining components, gets 100g mixture, add the water of 500g ~ 800g, boil 3 ~ 4 hours, filter, obtain the first filtrate, filter residue adds the water of 200g ~ 300g again, again boils 1 ~ 2 hour, filter, obtain the second filtrate, by the first filtrate and the mixing of the second filtrate, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder;
3rd step, by the first dried powder and the mixing of the second dried powder, obtains Traditional Chinese medicine immune preparation powder.
Present invention also offers a kind of for preventing the feed of infectious bronchitis of chicken, its raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamine supplement and for preventing the Traditional Chinese medicine immune preparation powder feed addictive of infectious bronchitis of chicken.
Wherein, in described feed, the weight portion of each material composition is respectively corn 90 weight portion ~ 110 weight portion, dregs of beans 30 weight portion ~ 50 weight portion, salt 2 weight portion ~ 4 weight portion, fish meal 8 weight portion ~ 12 weight portion, bone meal 3 weight portion ~ 5 weight portion, trace mineral supplement 2 weight portion ~ 4 weight portion, amino acid additive 2 weight portion ~ 4 weight portion, vitamine supplement 2 weight portion ~ 4 weight portion and Traditional Chinese medicine immune preparation powder feed addictive 15 weight portion ~ 20 weight portion.
Wherein, in described feed, the weight portion of each material composition is respectively corn 100 weight portion, dregs of beans 40 weight portion, salt 3 weight portion, fish meal 10 weight portion, bone meal 4 weight portion, trace mineral supplement 3 weight portion, amino acid additive 3 weight portion, vitamine supplement 3 weight portion and Traditional Chinese medicine immune preparation powder feed addictive 18 weight portion.
Present invention also offers the preparation method of above-mentioned feed, be specially:
The first step, prepares described Traditional Chinese medicine immune preparation powder feed addictive according to the method described above;
Second step, puts into fodder mixing machine together with the described Traditional Chinese medicine immune preparation powder feed addictive other raw material components in feedstuff and the first step obtained, and continuous uniform stirred after 1 ~ 3 hour, put into pulverizer and pulverized, and obtains feed.
Beneficial effect of the present invention:
Feed provided by the invention has significant effect in prevention infectious bronchitis of chicken, and has nontoxic, the advantage of resistance, drug residue free.
Detailed description of the invention
Chinese veterinarian treats infective bronchitis and adheres to eliminating evil principle large with righting two, and eliminating evil is the heresy dispelling harmful cause of disease-epidemic disease poison, namely suppresses or eliminates virulence factor, gets rid of pathological product.Righting is the premunition by strengthening body, improve immunologic function, righting is widely used in various infectious disease all the time, basic principle is yin-nourishing Bao Jin, and medicinal herb components can directly be degraded the toxin of pathogen, can also strengthen the immunologic function of body, virus is suppressed by clearing heat and detoxicating, be aided with clearing heat and eliminating phlegm, antiasthmatic-antitussive reaches eliminating evil object, and collaborative help class Chinese medicine strengthens immunity of organisms jointly, reaches the object of righting.
Theoretical according to traditional Chinese veterinary medicine, caused by invading in infectious bronchitis of chicken system epidemic disease poison, belong to warm heat disease category, the clinical Qi phase syndrome marquis with accumulation of heat in the lung is the most common, and accumulation of heat in the lung, should lose department clearly, and circulation of vital energy in the wrong direction phlegm is stopped up, therefore sees the diseases such as cough, asthma.Because of its characteristic of disease belong to heat, sick position at lung, control should clearing heat and detoxicating, should lung relieving asthma, relieving cough and reducing sputum.
Based on above-mentioned theory of traditional Chinese medical science, the present invention propose to invigorate the spleen and benefit qi, yin-nourishing Bao Jin is main, be aided with clearing heat and detoxicating, should lung relieving asthma, relieving cough and reducing sputum, realize the prevention to infectious bronchitis of chicken.
The invention provides a kind of for preventing the Traditional Chinese medicine immune preparation of infectious bronchitis of chicken, its bulk drug comprises Glabrous Sarcandra Herb, the root of large-flowered skullcap, great burdock achene, edible tulip, cape jasmine, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, fritillaria thunbergii, the fruit of Chinese magnoliavine, climbing groundsel, gynostemma pentaphylla, bush, date, subprostrate sophora, adenophora tetraphylla, the calyx and receptacle of a persimmon, hawthorn, radish seed, hairy euphorbia, Gorgon fruit, wilsonii, radix fici simplicissimae and Japanese cryptotaenia stem and leaf.
Further, described Traditional Chinese medicine immune preparation is only made up of above-mentioned raw materials medicine.
Fang Zhong, Glabrous Sarcandra Herb anti-inflammation, containing isofraxidin, fumaric acid, butanedioic acid, lignum-vitae base lignan, energetic supersession can be improved, broad-spectrum antiseptic, virus replication, to immunologic function, there is dual regulation, the root of large-flowered skullcap is clearing heat and detoxicating has the effect of releasing bronchial spasm, great burdock achene preventing phlegm from forming and stopping coughing, clearing throat, edible tulip is clearing heat and detoxicating, reducing phlegm and resolving masses, cape jasmine soothing liver-qi stagnation, clearing heat and promoting diuresis, the tuber of dwarf lilyturf Yin nourishing and lung moistening, preventing phlegm from forming and stopping coughing, sealwort, radix pseudostellariae, saponin(e contained by wilsonii, polysaccharide, flavonoids, organic acid and vitamin isoreactivity composition, have and reinforce vital energy, multiple arteries and veins takes off admittedly, reinforce the spleen to benefit the lung, promote the production of body fluid, to calm the nerves effect, body's immunity and anti-stress ability can be significantly improved, there is antiviral activity, the vine of multiflower knotweed can promote hematopoiesis function, there is tonic effect, cough-relieving that the fruit of Chinese wolfberry is nourishing Yin and moistening lung, fritillaria thunbergii is moistened the lung and relieve the cough and reduces phlegm, the fruit of Chinese magnoliavine is relieving cough and asthma, climbing groundsel is clearing heat and detoxicating, gynostemma pentaphylla has facilitation to humoral immunity, bush is promoting blood circulation and removing blood stasis, date air making-up and spleen enlivening, nourishing blood and tranquilization, subprostrate sophora removing toxic substances relieve sore throat, adenophora tetraphylla is moistened the lung and relieve the cough, nourishing the stomach to improve the production of body fluid, calyx and receptacle of a persimmon lowering the adverse flow of QI, hawthorn, radish seed stomach strengthening and digestion promoting, hairy euphorbia is clearing heat and detoxicating, dampness removing is antipruritic, Gorgon fruit supplementing the kidney to control the nocturnal, tonifying spleen antidiarrheal, radix fici simplicissimae invigorating the spleen for eliminating dampness, promoting the circulation of qi is reduced phlegm, Japanese cryptotaenia stem and leaf dispelling wind stopping cough, eliminating damp, detoxifying.
Glabrous Sarcandra Herb: latin name Sarcandrae Herba, slightly warm in nature, bitter, pungent, there is anti-inflammation, dispelling wind and removing obstruction in the meridians, effect of blood circulation promoting and dispersing pathogen accumulation, cure mainly the cards such as pneumonia, appendicitis, cellulitis, arthralgia due to wind-dampness, injury from falling down, tumour.
The root of large-flowered skullcap: latin name Scutellariae Radix, bitter, cold in nature, enter the heart, lung, stomach, courage, large intestine channel, have heat-clearing and damp-drying drug, purging intense heat and detonicating, antiabortive, the effect of hemostasis, is mainly used in damp and hot caused diarrhoea, dysentery, jaundice, heat drenches; Cough with lung heat, thirsty pharyngalgia, also can be used for fetal movement with fever, and hot malicious fire-evil invades the swollen card of sore carbuncle poison of excessive skin.
Great burdock achene: taste is pungent is bitter; Cold in nature, return lung, stomach warp, has dispelling wind and heat from the body, clearing heat and detoxicating promoting eruption, and a surname's lung relieve sore throat falls apart swollen effect, cure mainly anemopyretic cold, warm disease from the beginning of; Wind-heat or cough with lung heat, cough up phlegm not smooth; Abscess of throat; Macula is not saturating; At the measles initial stage, rash goes out not smooth and rubella itch; The card such as sore swollen toxin and mumps.
Edible tulip: taste is sweet, micro-pungent, cool in nature, returns liver, the spleen channel, has clearing heat and detoxicating, effect of reducing phlegm and resolving masses, to swell serious case of furuncle for carbuncle, scrofula subcutaneous nodule, scrofula, the cards such as snake bite and insect sting.
Cape jasmine: bitter, cold in nature, enter the heart, lung, three burnt, have the effect of relieving restlessness purging intense heat, soothing liver-qi stagnation, clearing heat and promoting diuresis, cooling blood and hemostasis, be mainly used in the vexed uneasiness of the strongly fragrant chest gastral cavity of warm heat disease heat, bother not peaceful; Liver depression is not relaxed or Liver Channel has having a dizzy spell of heat, pain in chest and hypochondrium, hot eyes dry throat; Jaundice with damp-heat pathogen; The symptoms such as the abdominal distention of qi depression to blood stasis.
The tuber of dwarf lilyturf: latin name Ophiopogonis Radix, sweet, the micro-hardship of taste, cold nature, enter the heart, lung, stomach warp, there is Yin nourishing and lung moistening, effect that preventing phlegm from forming and stopping coughing, heat-clearing are nourished heart, cure mainly the dryness evil impariment of the lung or the lung-dryness syndrome due to yin deficiency has the dry cough phlegm of heat to stick, labor is coughed hemoptysis, dry throat nasal cavity dryness, lung carbuncle, thermal burn stomach-Yin or the dry mouth and throat caused by deficiency of stomach-Yin, the red few tongue of tongue, vague epigastralgia, interior heat is quenched one's thirst, dry feces, the deficiency of the heart-yin and warm disease heat evil are disturbed and the heart-nutriment and the dysphoria and insomnia that causes, and tongue is deep red and dry waits card.
Sealwort: taste is sweet, property is put down, and enter lung, spleen, kidney channel, have nourshing kidney moistening lung, the effect of invigorating the spleen and benefiting qi, for the lung-dryness syndrome due to yin deficiency, dry cough phlegm is few, many drinks of quenching one's thirst, weakness of the spleen and the stomach, Spleen-Qi Deficiency or deficiency of spleen-YIN, deficiency of kidney essence, soreness and weakness of waist and knees, the cards such as poliosis.
Radix pseudostellariae: sweet, the micro-hardship of taste, property is put down, and enters spleen, lung channel, has air making-up and spleen enlivening, the effect that moistening lung is promoted the production of body fluid, the few burnout of food for deficiency-weakness of spleen-QI, deficiency of stomach-Yin, the beneficial temper of energy, nourishing stomach-YIN, for the deficiency syndrome of the lung cough caused by dryness of deficiency of vital energy Tianjin wound and palpitaition egersis, abnormal heat sweat many, energy nourishing generate fluid, controls deficiency of vital energy xeropulmonary cough, the card such as palpitaition egersis, hidrosis of deficiency of both qi and yin.
The vine of multiflower knotweed: sweet, the micro-hardship of taste, property is put down; The thoughts of returning home, Liver Channel, have effect of energy mental-tranquilization, dispelling wind and removing obstruction in the meridians, cure mainly insomnia and dreamful sleep, deficiency of blood bodily pain, numbness, arthralgia due to wind-dampness, the cards such as wind sore mange.
The fruit of Chinese wolfberry: taste is sweet, property is flat, enters liver, kidney channel, have tonify the liver and kidney, nourish blood enrich blood, benefiting shrewd head, the effect that moistens the lung and relieve the cough, be mainly used in liver kidney two void, the soreness and weakness of waist and knees of asthenia of essence and blood, dizziness and tinnitus, seminal emission tinnitus, unconsciously sweat and tire; The impotence of the insufficiency of the kidney yang, sterile; The eyes of deficiency of YIN-essence,impairment of YIN-essence, deficiency of liver-blood dim-sighted and deficiency of Yin labor such as to be coughed at the card.
Fritillaria thunbergii: bitter, cold in nature, enter lung, the heart channel of Hang-Shaoyin, have clearing heat and eliminating phlegm, effect of powder detoxifcation, cures mainly cough due to wind-heat evil, lung carbuncle larynx numbness, scrofula, the cards such as sore swollen toxin.
The fruit of Chinese magnoliavine: warm in nature, taste is sour, sweet, returns lung, the heart, kidney channel, has convergence astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, effect of kidney calming, cure mainly void of coughing for a long time to breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and feeble pulse of losing heart, interior heat is quenched one's thirst, the cards such as palpitation and insomnia.
Climbing groundsel: cold in nature, bitter, returns lung, Liver Channel, has effect that is clearing heat and detoxicating, improving eyesight dampness removing, have the cards such as carbuncle sore tumefacting virus, cold, fever, red eye, swell pain, dysentery, skin eczema, climbing groundsel has antibacterial activity to staphylococcus aureus, ETEC, shigella dysenteriae.
Gynostemma pentaphylla: cold in nature, taste is sweet, returns lung, spleen, kidney channel, useful gas, calms the nerves, hypotensive effect, and for deficiency of vital energy and physically weak, weak breath is weak; Vexed insomnia; High blood pressure, Light-headedness; Virus hepatitis; Tumor in digestive tract; Chronic bronchitis, the polysaccharide that gynostemma pentaphylla is rich in can improve serum hemolysis cellulose content, has facilitation to humoral immunity, and the total saposins that gynostemma pentaphylla is rich in can promote lymphocyte transformation, improves the activity of DNA polysaccharide, promotes the synthesis of lymphocyte DNA.
Bush: taste is sweet, become, property is put down, and the thoughts of returning home, liver, the spleen channel, have promoting blood circulation, and effect of swelling and pain relieving, cures mainly traumatic injury, the fracture injury of the tissues, and stasis swells and ache, through closing dysmenorrhoea, postpartum stasis blocking, the cards such as chest ventral spine pain.
Date: taste is sweet, warm in nature, enter spleen, stomach warp, there is the effect of air making-up and spleen enlivening, nourishing blood and tranquilization, harmonizing yingfen and weifen, the mitigation property of medicine, for weakness of the spleen and the stomach, fatigue and asthenia, anorexia and loose stool, the cards such as insufficiency of vital energy and blood, has a headache and fever, sweating hot blast.
Subprostrate sophora: bitter, cold in nature, enter the heart, lung, large intestine channel, there is removing toxic substances relieve sore throat, clearing heat and promoting diuresis, effect that desinsection is anticancer, the cards such as abscess of throat, gum swells dentalgia, cough with lung heat, dysentery, jaundice, the swollen favus of the scalp of heat.
Adenophora tetraphylla: sweet, the micro-hardship of taste, cold nature, enters lung, stomach warp, moistens the lung and relieve the cough, the effect of nourishing the stomach to improve the production of body fluid, is mainly used in the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, labor cough the cards such as phlegm blood, the pharynx of deficiency of stomach-Yin, mouthfeel is dry, the red few tongue of constipation, tongue.
The calyx and receptacle of a persimmon: bitter, flat, return stomach warp, there is effect of lowering the adverse flow of QI, cure mainly hiccup; Gas; The cards such as gastric disorder causing nausea.
Taste acid, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel, and for food digesting stomach fortifying, promoting the circulation of qi is fallen apart the stasis of blood, and be mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, hawthorn be the staple for the treatment of indigestion, and hawthorn can increase the secretion of peptic digest enzyme, promotes to digest; To shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc., there is obvious inhibitory action.
Radish seed: property is put down, and taste is pungent, sweet, returns lung, spleen, stomach warp, has the de-swelling that helps digestion, effect of lowering the adverse-rising QI to resolve phlegm, cures mainly retention of food and drink, abdominal distention, constipation, stagnant rushes down dysentery, phlegm stops up cards such as breathing with cough.
Hairy euphorbia: mildly bitter flavor, micro-acid, cool in nature, have clearing heat and detoxicating, effect that dampness removing is antipruritic, for bacillary dysentery, amoebic dysentery, enteritis, enteron aisle trichomonad, indigestion, bronchitis, pyelonephritis; The cards such as eczema, dermatitis, pruitus are controlled in external application.
Gorgon fruit: taste is sweet, puckery, property is put down.Return spleen, kidney channel.There is supplementing the kidney to control the nocturnal, tonifying spleen antidiarrheal, the function that clearing damp is only with, cure mainly emission, splenasthenic diarrhea, insufficiency of the spleen gonorrhoea, be with inferior card.
Sting five power: latin name Acanthopanacis Senticosi Radix et Rhizomaseu Caulis, taste is pungent, bitter, micro-sweet, warm in nature, enter spleen, kidney, the heart channel of Hang-Shaoyin, have and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, the effect of dispelling rheumatism, soft for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence, be slow in action, the card such as body void is thin and weak, traumatic injury, fracture, oedema, beriberi, uncontrolled urination are itched.
Radix fici simplicissimae: sweet, tepor, has invigorating the spleen for eliminating dampness, and promoting the circulation of qi is reduced phlegm, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, and cure mainly pulmonary tuberculosis cough, chronic bronchitis, rheumatic arthritis, waist has a pain in the leg, insufficiency of the spleen edema, after being ill the card such as night sweat.
Japanese cryptotaenia stem and leaf: taste is pungent is bitter; Property is put down, and has dispelling wind stopping cough; Eliminating damp, detoxifying; Effect of blood-activating analgetic, cures mainly pneumonia, pulmonary abscess, gonorrhoea, hernia, acute toothache, and ulcer malignant boil swells, herpes zoster, the cards such as pruitus.
In described Traditional Chinese medicine immune preparation, the weight portion of each bulk drug is respectively: Glabrous Sarcandra Herb 25 weight portion ~ 35 weight portion, the root of large-flowered skullcap 45 weight portion ~ 55 weight portion, great burdock achene 25 weight portion ~ 35 weight portion, edible tulip 35 weight portion ~ 45 weight portion, cape jasmine 45 weight portion ~ 55 weight portion, the tuber of dwarf lilyturf 55 weight portion ~ 65 weight portion, sealwort 45 weight portion ~ 55 weight portion, radix pseudostellariae 75 weight portion ~ 85 weight portion, the vine of multiflower knotweed 35 weight portion ~ 45 weight portion, the fruit of Chinese wolfberry 55 weight portion ~ 65 weight portion, fritillaria thunbergii 20 weight portion ~ 30 weight portion, the fruit of Chinese magnoliavine 25 weight portion ~ 35 weight portion, climbing groundsel 20 weight portion ~ 30 weight portion, gynostemma pentaphylla 45 weight portion ~ 55 weight portion, bush 20 weight portion ~ 30 weight portion, date 35 weight portion ~ 45 weight portion, subprostrate sophora 25 weight portion ~ 35 weight portion, adenophora tetraphylla 45 weight portion ~ 55 weight portion, the calyx and receptacle of a persimmon 20 weight portion ~ 30 weight portion, hawthorn 25 weight portion ~ 35 weight portion, radish seed 20 weight portion ~ 30 weight portion, hairy euphorbia 25 weight portion ~ 35 weight portion, Gorgon fruit 35 weight portion ~ 45 weight portion, wilsonii 30 weight portion ~ 40 weight portion, radix fici simplicissimae 30 weight portion ~ 40 weight portion and Japanese cryptotaenia stem and leaf 20 weight portion ~ 30 weight portion.
Further preferably, in described Traditional Chinese medicine immune preparation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 28 weight portion ~ 32 weight portion, the root of large-flowered skullcap 48 weight portion ~ 52 weight portion, great burdock achene 28 weight portion ~ 32 weight portion, edible tulip 38 weight portion ~ 42 weight portion, cape jasmine 48 weight portion ~ 52 weight portion, the tuber of dwarf lilyturf 58 weight portion ~ 62 weight portion, sealwort 48 weight portion ~ 52 weight portion, radix pseudostellariae 78 weight portion ~ 82 weight portion, the vine of multiflower knotweed 38 weight portion ~ 42 weight portion, the fruit of Chinese wolfberry 58 weight portion ~ 62 weight portion, fritillaria thunbergii 23 weight portion ~ 27 weight portion, the fruit of Chinese magnoliavine 28 weight portion ~ 32 weight portion, climbing groundsel 23 weight portion ~ 27 weight portion, gynostemma pentaphylla 48 weight portion ~ 52 weight portion, bush 23 weight portion ~ 27 weight portion, date 38 weight portion ~ 42 weight portion, subprostrate sophora 28 weight portion ~ 32 weight portion, adenophora tetraphylla 48 weight portion ~ 52 weight portion, the calyx and receptacle of a persimmon 23 weight portion ~ 27 weight portion, hawthorn 28 weight portion ~ 32 weight portion, radish seed 23 weight portion ~ 27 weight portion, hairy euphorbia 28 weight portion ~ 32 weight portion, Gorgon fruit 38 weight portion ~ 42 weight portion, wilsonii 33 weight portion ~ 37 weight portion, radix fici simplicissimae 33 weight portion ~ 37 weight portion and Japanese cryptotaenia stem and leaf 23 weight portion ~ 27 weight portion.
Further preferred, in described Traditional Chinese medicine immune preparation, the weight portion of each bulk drug is respectively Glabrous Sarcandra Herb 30 weight portion, the root of large-flowered skullcap 50 weight portion, great burdock achene 30 weight portion, edible tulip 40 weight portion, cape jasmine 50 weight portion, the tuber of dwarf lilyturf 60 weight portion, sealwort 50 weight portion, radix pseudostellariae 80 weight portion, the vine of multiflower knotweed 40 weight portion, the fruit of Chinese wolfberry 60 weight portion, fritillaria thunbergii 25 weight portion, the fruit of Chinese magnoliavine 30 weight portion, climbing groundsel 25 weight portion, gynostemma pentaphylla 50 weight portion, bush 25 weight portion, date 40 weight portion, subprostrate sophora 30 weight portion, adenophora tetraphylla 50 weight portion, the calyx and receptacle of a persimmon 25 weight portion, hawthorn 30 weight portion, radish seed 25 weight portion, hairy euphorbia 30 weight portion, Gorgon fruit 40 weight portion, wilsonii 35 weight portion, radix fici simplicissimae 35 weight portion and Japanese cryptotaenia stem and leaf 25 weight portion.
The first step, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, gynostemma pentaphylla, date, adenophora tetraphylla, Gorgon fruit and wilsonii are mixed in proportion, getting mixture 100g loads in percolator, add the white wine 600g ~ 800g of 50 DEG C ~ 55 DEG C, soak 20 hours ~ 30 hours under the condition of 25 DEG C ~ 35 DEG C, regulate percolator valve, white wine liquid is slowly oozed, and the speed of oozing is 2 ~ 4mL per minute, collects drip, obtain the percolate of 700mL ~ 1L, concentrated, removing white wine, dry, pulverize, obtain the first dried powder;
Second step, mixes in proportion by remaining components, gets 100g mixture, add the water of 500g ~ 800g, boil 3 ~ 4 hours, filter, obtain the first filtrate, filter residue adds the water of 200g ~ 300g again, again boils 1 ~ 2 hour, filter, obtain the second filtrate, by the first filtrate and the mixing of the second filtrate, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder;
3rd step, by the first dried powder and the mixing of the second dried powder, obtains Traditional Chinese medicine immune preparation powder.
Traditional Chinese medicine immune preparation provided by the invention can be admixed in feed and take for chicken, or is dissolved in water and gavages to chicken.
Present invention also offers a kind of for preventing the feed of infectious bronchitis of chicken, its raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamine supplement and for preventing the Traditional Chinese medicine immune preparation powder feed addictive of infectious bronchitis of chicken.
Further, described feed is only made up of above-mentioned raw materials.
Wherein, in described feed, the weight portion of each material composition is respectively corn 90 weight portion ~ 110 weight portion, dregs of beans 30 weight portion ~ 50 weight portion, salt 2 weight portion ~ 4 weight portion, fish meal 8 weight portion ~ 12 weight portion, bone meal 3 weight portion ~ 5 weight portion, trace mineral supplement 2 weight portion ~ 4 weight portion, amino acid additive 2 weight portion ~ 4 weight portion, vitamine supplement 2 weight portion ~ 4 weight portion and Traditional Chinese medicine immune preparation powder feed addictive 15 weight portion ~ 20 weight portion.
Further preferably, in described feed, the weight portion of each material composition is respectively corn 100 weight portion, dregs of beans 40 weight portion, salt 3 weight portion, fish meal 10 weight portion, bone meal 4 weight portion, trace mineral supplement 3 weight portion, amino acid additive 3 weight portion, vitamine supplement 3 weight portion and Traditional Chinese medicine immune preparation powder feed addictive 18 weight portion.
Trace mineral supplement can be the trace mineral supplement of various routine, simple acylate can be used, as ironic citrate, also trace element and amino-acid chelate can be used, as amino acid iron, the trace element added mainly contains iron, zinc, copper, manganese, iodine, cobalt, selenium, molybdenum, also can use composite trace element premix, as Great Britain and America's that Beijing You Libao biotechnology Co., Ltd provides.
Amino acid additive comprises the various conventional amino acid such as serine, glutamic acid, glycine, isoleucine, leucine, alanine, proline, also can adopt amino acid premix, the composite aminophenol powder of as above sea cowry energy Chemical Co., Ltd. production.
Vitamine supplement comprises the various conventional vitamin such as riboflavin, vitamin C, vitamin E, vitamin A, Cobastab, also can adopt vitamin premix, as the excellent dimension element that Beijing You Libao Bioisystech Co., Ltd produces.
Present invention also offers the preparation method of above-mentioned feed, be specially:
The first step, prepares described Traditional Chinese medicine immune preparation powder feed addictive according to the method described above;
Second step, puts into fodder mixing machine together with the described Traditional Chinese medicine immune preparation powder feed addictive other raw material components in feedstuff and the first step obtained, and continuous uniform stirred after 1 ~ 3 hour, put into pulverizer and pulverized, and obtains feed.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 Traditional Chinese medicine immune preparation 1
By the 60g tuber of dwarf lilyturf, sealwort 50g, radix pseudostellariae 80g, vine of multiflower knotweed 40g, fruit of Chinese wolfberry 60g, gynostemma pentaphylla 50g, date 40g, adenophora tetraphylla 50g, Gorgon fruit 40g and wilsonii 35g mixes in proportion, gets mixture 100g and loads in percolator, add the white wine 700g of 50 DEG C, soak 25 hours under the condition of 30 DEG C, regulate percolator valve, white wine liquid is slowly oozed, the speed of oozing is 3mL per minute, collects drip, obtains the percolate of 800mL, concentrated, removing white wine, dry, pulverize, obtain the first dried powder, by Glabrous Sarcandra Herb 30g, root of large-flowered skullcap 50g, great burdock achene 30g, edible tulip 40g, cape jasmine 50g, fritillaria thunbergii 25g, fruit of Chinese magnoliavine 30g, climbing groundsel 25g, bush 25g, subprostrate sophora 30g, calyx and receptacle of a persimmon 25g, hawthorn 30g, radish seed 25g, hairy euphorbia 30g, radix fici simplicissimae 35g and Japanese cryptotaenia stem and leaf 25g mixes, and gets 100g mixture, adds the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boils 2 hours, filters, obtain the second filtrate, by the first filtrate and the mixing of the second filtrate, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder, by the first dried powder and the mixing of the second dried powder, obtain Traditional Chinese medicine immune preparation 1.
Embodiment 2 Traditional Chinese medicine immune preparation 2
By the 58g tuber of dwarf lilyturf, sealwort 48g, radix pseudostellariae 78g, vine of multiflower knotweed 38g, fruit of Chinese wolfberry 58g, gynostemma pentaphylla 48g, date 38g, adenophora tetraphylla 48g, Gorgon fruit 38g and wilsonii 33g mixes in proportion, gets mixture 100g and loads in percolator, add the white wine 700g of 50 DEG C, soak 25 hours under the condition of 30 DEG C, regulate percolator valve, white wine liquid is slowly oozed, the speed of oozing is 3mL per minute, collects drip, obtains the percolate of 800mL, concentrated, removing white wine, dry, pulverize, obtain the first dried powder, by Glabrous Sarcandra Herb 28g, root of large-flowered skullcap 48g, great burdock achene 28g, edible tulip 38g, cape jasmine 48g, fritillaria thunbergii 23g, fruit of Chinese magnoliavine 28g, climbing groundsel 23g, bush 23g, subprostrate sophora 28g, calyx and receptacle of a persimmon 23g, hawthorn 28g, radish seed 23g, hairy euphorbia 28g, radix fici simplicissimae 33g and Japanese cryptotaenia stem and leaf 23g mixes, and gets 100g mixture, adds the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boils 2 hours, filters, obtain the second filtrate, by the first filtrate and the mixing of the second filtrate, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder, by the first dried powder and the mixing of the second dried powder, obtain Traditional Chinese medicine immune preparation 2.
Embodiment 3 Traditional Chinese medicine immune preparation 3
By the 62g tuber of dwarf lilyturf, sealwort 52g, radix pseudostellariae 82g, vine of multiflower knotweed 42g, fruit of Chinese wolfberry 62g, gynostemma pentaphylla 52g, date 42g, adenophora tetraphylla 52g, Gorgon fruit 42g and wilsonii 37g mixes in proportion, gets mixture 100g and loads in percolator, add the white wine 700g of 50 DEG C, soak 25 hours under the condition of 30 DEG C, regulate percolator valve, white wine liquid is slowly oozed, the speed of oozing is 3mL per minute, collects drip, obtains the percolate of 800mL, concentrated, removing white wine, dry, pulverize, obtain the first dried powder, by Glabrous Sarcandra Herb 32g, root of large-flowered skullcap 52g, great burdock achene 32g, edible tulip 42g, cape jasmine 52g, fritillaria thunbergii 27g, fruit of Chinese magnoliavine 32g, climbing groundsel 27g, bush 27g, subprostrate sophora 32g, calyx and receptacle of a persimmon 27g, hawthorn 32g, radish seed 27g, hairy euphorbia 32g, radix fici simplicissimae 37g and Japanese cryptotaenia stem and leaf 27g mixes, and gets 100g mixture, adds the water of 600g, boil 4 hours, filter, obtain the first filtrate, filter residue adds the water of 300g again, again boils 2 hours, filters, obtain the second filtrate, by the first filtrate and the mixing of the second filtrate, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder, by the first dried powder and the mixing of the second dried powder, obtain Traditional Chinese medicine immune preparation 3.
Embodiment 4 toxicological experiment
Acute toxicity testing
Select Kunming mouse 20, female half and half, body weight (20+2) g, thered is provided by Qingdao City's Experimental Animal Center, be dissolved in water by Traditional Chinese medicine immune preparation prepared by embodiment 1, obtaining crude drug concentration is the solution of 1g/ml, gavages mouse, through preliminary experiment, fail to detect the LD of oral administration
50, therefore survey its maximal tolerance dose, with the administration volume of 1.4ml/10g body weight, gavage 2 times/d, interval 6h, to observation post administration 7d, record animal dead and toxicity symptom, at the end of experiment, by all animals process, dissect, visually observe each main organs lesion tissue situation, after gavaging 140g crude drug/kg for 2 times, animal activity, feed water inlet does not show any abnormalities, observe 7d animal dead, gross necropsy has no the obvious exception of main organs tissue, therefore, the maximum dosage-feeding of Chinese herbal granules is > 140g crude drug/kg, this dosage is equivalent to 70 times of maximum oral dose 2g crude drug/kg clinical adult (by 60kg) every day.
Long term toxicity test
Select 40 male SD rats, weight (180 ± 20) g, thered is provided by Qingdao City's Experimental Animal Center, be divided into 2 groups at random, blank group and Chinese drug-treated group, often organize 20, blank group gives distilled water, Traditional Chinese medicine immune preparation prepared by embodiment 1 is dissolved in water, obtaining crude drug concentration is the solution of 1g/ml, gavage rat, the amount of gavaging is 50g crude drug/kg, on every Mondays to gastric infusion 1 time in morning Saturday, continuous 180d, administration volume is 2mL/100g body weight, every day observes rat general state before administration and during administration, sign, food ration, drinking-water and ight soil situation.During administration 90d after last administration 24h, the extraction 6 of each group, male and female half and half; During 180d after last administration 24h, the extraction 6 of each group, male and female half and half; After drug withdrawal, 30d respectively organizes extraction 6, male and female half and half, anaesthetize with urethane, blood is got from abdominal aortic, each group is all killed and gets animal, checks hematology and blood parameters, after getting blood, amass wealth by heavy taxation at once core, liver,kidney,spleen, lung, adrenal gland, thyroid gland, thymus gland, testis, ovary, uterus, brain, the internal organs such as prostate weigh, and make pathological examination according to weight calculator official weight coefficient.
On inspection, during successive administration, the activity of animal, body weight, food ration, stool and hair luster degree no abnormality seen, animal has no dead, naked eyes have no obvious pathology, each group of rat peripheral hemogram checking is all in normal range (NR), and physiochemical indice is all in normal range (NR), and Chinese drug-treated group Rats Organs and Tissues coefficient does not have significant difference compared with blank group.
Embodiment 5 feed 1
Fodder mixing machine is put into together with the Traditional Chinese medicine immune preparation 1.8kg that corn 10kg, dregs of beans 4kg, salt 0.3kg, fish meal 0.1kg, bone meal 0.4kg, trace mineral supplement Great Britain and America that (Beijing You Libao biotechnology Co., Ltd provides) 0.3kg, amino acid additive composite aminophenol powder (upper sea cowry energy Chemical Co., Ltd. produces) 0.3kg, the excellent dimension element of vitamine supplement (production of Beijing You Libao Bioisystech Co., Ltd) 0.3kg and embodiment 1 are prepared, after continuous uniform stirs 3 hours, put into pulverizer to pulverize, obtain feed 1.
Comparative example 1 feed 2
Corn 10kg, dregs of beans 4kg, salt 0.3kg, fish meal 0.1kg, bone meal 0.4kg, trace mineral supplement Great Britain and America that (Beijing You Libao biotechnology Co., Ltd provides) 0.3kg, amino acid additive composite aminophenol powder (upper sea cowry energy Chemical Co., Ltd. produces) 0.3kg, the excellent dimension element of vitamine supplement (production of Beijing You Libao Bioisystech Co., Ltd) 0.3kg are put into fodder mixing machine together, after continuous uniform stirs 3 hours, put into pulverizer to pulverize, obtain feed 2.
Embodiment 6 zoopery
Animal used as test
Select the healthy SPF chicken 400 of 7 ages in days, by Qingdao, Nanjing brocade animal used as test Co., Ltd provides, and without IBV epidemic prevention, is divided into 4 groups at random, often organizes 100.
Normal healthy controls group: do not attack poison, does not feed any medicine, isolated rearing, feeding corn feed.
Attack malicious control group: after attacking poison, do not feed any medicine, isolated rearing, feeding corn feed.
Prevent 1 group: attack the feed 1 that poison starts feeding embodiment 5 and prepares for first 3 days.
Prevent 2 groups: attack the feed 2 that poison starts feeding comparative example 1 and prepares for first 3 days.
Experimental drug
Feed 1 prepared by embodiment 5 and feed 2 prepared by comparative example 1.
IBV
Attack poison IBV M41 velogen strain, provided by China Veterinary Drugs Supervisory Inst., after virus 1: 10 being diluted during use through tracheae inoculation test chicken 0.2ml/ only.
Syndrome Scale and curative effect judging standard
Determine that the infective dose of IBV-M41 strain kind poison is that every plumage 0.2mL carries out collunarium inoculation through trial test.In time attacking the most chicken of malicious control group and fall ill, clinical symptoms are carried out to each group of chicken and scores, and test chicken is cutd open inspection, cut open inspection symptom score, calculate each group of result of scoring, conclude according to curative effect judging standard.Clinical symptoms classification, cut open inspection Syndrome Scale and curative effect determinate standard specific as follows:
Clinical symptoms classification
One-level (0 point): the chicken state of mind is good, diet is all normal for, activity.
Secondary (1 point): cough in discontinuity, accidental nasal cavity has mucus, gets rid of head, food effect is little, and walking is normal.
Three grades (2 points): expiratory dyspnea, tracheae has rale, and spirit is depressed, and feather is inverse vertical, and peel off slow-witted vertical, appetite declines or do not eat.
Level Four (3 points): expiratory dyspnea, death by suffocation.
Cut open inspection Syndrome Scale
One-level (0 point): without obvious pathological change.
Secondary (1 point): have mucus secretion in nasal cavity, has thin mucus secretion in tracheae and bronchus.The micro-muddiness of air bag.
Three grades (2 points): the secretion having more thickness in tracheae hypomere and bronchus, have no hemorrhage, air bag thickens.
Level Four (3 points): have yellow cheesy exudate in tracheae hypomere and bronchus.Some tracheae hypomeres and bronchus place have ring-type hemorrhage.Air bag thickens.
Curative effect determinate standard
Effective: to refer to attack 48h after poison, prevention group with attack compared with malicious control group, main clinic symptoms, the pathological change of morbidity chicken obviously improve, i.e. 60% < therapeutic index < 100%.
Effective: to refer to attack 48h after poison, prevention group with attack compared with malicious control group, main clinic symptoms, the pathological change of morbidity chicken make moderate progress, i.e. 30% < therapeutic index < 60%.
Invalid: to refer to attack 48h after poison, prevention group with attack compared with malicious control group, main clinic symptoms, the pathological change of morbidity chicken are not improved or add severe one to some extent, be i.e. therapeutic index < 30%.
Note: therapeutic index=(attack malicious control group score-prevention group scores) ÷ attack malicious control group score × 100%.
Data process&analysis
Each group of data all use mean soil standard deviation
represent, each group mean does test of normality and duplicate measurements homogeneity test of variance, with inspection younger between one-way analysis of variance group), P < 0.05 is for differing significantly, and P < 0.01 is difference highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Result
Attack malicious control group most of chicken after attacking malicious 48h and occur significantly cough, there is the symptom such as rale, expiratory dyspnea in part chicken, sick chicken spirit is depressed, poor appetite, inspection is cutd open to dead chicken, occurs that infectious bronchitis of chicken typical pathologic changes, illustrate and attack poison success.
Traditional Chinese medicine immune preparation of the present invention to the preventive effect of infectious bronchitis of chicken in table 1.
Table 1 Traditional Chinese medicine immune preparation is to the preventive effect of infectious bronchitis of chicken
As can be seen from Table 1, adopt the prevention group incidence of disease of Traditional Chinese medicine immune preparation of the present invention to be significantly less than the prevention group of attacking malicious control group and not adding Traditional Chinese medicine immune preparation of the present invention, illustrate that the preventive effect of this Traditional Chinese medicine immune preparation is remarkable.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (3)
1. one kind for preventing the feed of infectious bronchitis of chicken, it is characterized in that: raw material comprises corn, dregs of beans, salt, fish meal, bone meal, trace mineral supplement, amino acid additive, vitamine supplement and for preventing the Traditional Chinese medicine immune preparation powder feed addictive of infectious bronchitis of chicken, the weight portion of each material composition is respectively corn 90 weight portion ~ 110 weight portion, dregs of beans 30 weight portion ~ 50 weight portion, salt 2 weight portion ~ 4 weight portion, fish meal 8 weight portion ~ 12 weight portion, bone meal 3 weight portion ~ 5 weight portion, trace mineral supplement 2 weight portion ~ 4 weight portion, amino acid additive 2 weight portion ~ 4 weight portion, vitamine supplement 2 weight portion ~ 4 weight portion and Traditional Chinese medicine immune preparation powder feed addictive 15 weight portion ~ 20 weight portion,
The bulk drug of described Traditional Chinese medicine immune preparation powder feed addictive is by Glabrous Sarcandra Herb, the root of large-flowered skullcap, great burdock achene, edible tulip, cape jasmine, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, fritillaria thunbergii, the fruit of Chinese magnoliavine, climbing groundsel, gynostemma pentaphylla, bush, date, subprostrate sophora, adenophora tetraphylla, the calyx and receptacle of a persimmon, hawthorn, radish seed, hairy euphorbia, Gorgon fruit, wilsonii, radix fici simplicissimae and Japanese cryptotaenia stem and leaf are formed, and in described Traditional Chinese medicine immune preparation powder feed addictive, the weight portion of each bulk drug is respectively: Glabrous Sarcandra Herb 25 weight portion ~ 35 weight portion, the root of large-flowered skullcap 45 weight portion ~ 55 weight portion, great burdock achene 25 weight portion ~ 35 weight portion, edible tulip 35 weight portion ~ 45 weight portion, cape jasmine 45 weight portion ~ 55 weight portion, the tuber of dwarf lilyturf 55 weight portion ~ 65 weight portion, sealwort 45 weight portion ~ 55 weight portion, radix pseudostellariae 75 weight portion ~ 85 weight portion, the vine of multiflower knotweed 35 weight portion ~ 45 weight portion, the fruit of Chinese wolfberry 55 weight portion ~ 65 weight portion, fritillaria thunbergii 20 weight portion ~ 30 weight portion, the fruit of Chinese magnoliavine 25 weight portion ~ 35 weight portion, climbing groundsel 20 weight portion ~ 30 weight portion, gynostemma pentaphylla 45 weight portion ~ 55 weight portion, bush 20 weight portion ~ 30 weight portion, date 35 weight portion ~ 45 weight portion, subprostrate sophora 25 weight portion ~ 35 weight portion, adenophora tetraphylla 45 weight portion ~ 55 weight portion, the calyx and receptacle of a persimmon 20 weight portion ~ 30 weight portion, hawthorn 25 weight portion ~ 35 weight portion, radish seed 20 weight portion ~ 30 weight portion, hairy euphorbia 25 weight portion ~ 35 weight portion, Gorgon fruit 35 weight portion ~ 45 weight portion, wilsonii 30 weight portion ~ 40 weight portion, radix fici simplicissimae 30 weight portion ~ 40 weight portion and Japanese cryptotaenia stem and leaf 20 weight portion ~ 30 weight portion.
2. feed according to claim 1, is characterized in that: the preparation method of described Traditional Chinese medicine immune preparation powder feed addictive is specially,
The first step, the tuber of dwarf lilyturf, sealwort, radix pseudostellariae, the vine of multiflower knotweed, the fruit of Chinese wolfberry, gynostemma pentaphylla, date, adenophora tetraphylla, Gorgon fruit and wilsonii are mixed in proportion, getting mixture 100g loads in percolator, add the white wine 600g ~ 800g of 50 DEG C ~ 55 DEG C, soak 20 hours ~ 30 hours under the condition of 25 DEG C ~ 35 DEG C, regulate percolator valve, white wine liquid is slowly oozed, and the speed of oozing is 2 ~ 4mL per minute, collects drip, obtain the percolate of 700mL ~ 1L, concentrated, removing white wine, dry, pulverize, obtain the first dried powder;
Second step, mixes in proportion by remaining components, gets 100g mixture, add the water of 500g ~ 800g, boil 3 ~ 4 hours, filter, obtain the first filtrate, filter residue adds the water of 200g ~ 300g again, again boils 1 ~ 2 hour, filter, obtain the second filtrate, by the first filtrate and the mixing of the second filtrate, concentrated, except anhydrating, dry, pulverize, obtain the second dried powder;
3rd step, by the first dried powder and the mixing of the second dried powder, obtains Traditional Chinese medicine immune preparation.
3. the preparation method of feed described in claim 2, is characterized in that:
The first step, prepares described Traditional Chinese medicine immune preparation powder feed addictive according to method described in claim 2;
Second step, puts into fodder mixing machine together with the described Traditional Chinese medicine immune preparation powder feed addictive other raw material components in feedstuff and the first step obtained, and continuous uniform stirred after 1 ~ 3 hour, put into pulverizer and pulverized, and obtains feed.
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| CN104222631B (en) * | 2014-09-10 | 2016-08-17 | 杨高林 | For treating the feedstuff of rabbit coccidiosis |
| CN104222632B (en) * | 2014-09-10 | 2017-02-08 | 赵玉妹 | Feed for preventing coccidiosis of rabbits |
| CN104222520A (en) * | 2014-09-16 | 2014-12-24 | 青岛华仁技术孵化器有限公司 | Feed additive for enhancing immunity of piglets |
| CN105053630A (en) * | 2015-07-31 | 2015-11-18 | 张翔 | Feed containing Chinese medicinal additive for controlling goose laryngotracheitis |
| CN105519812A (en) * | 2016-01-01 | 2016-04-27 | 闫冷 | Chick infectious broncheitis treatment feed additive |
| CN106306533A (en) * | 2016-08-20 | 2017-01-11 | 丁永军 | Traditional Chinese medicine feed for preventing and treating infectious bronchitis and preparation method thereof |
| CN107279571A (en) * | 2017-07-20 | 2017-10-24 | 无为县青松养殖有限公司 | A kind of laying hen disease-resistant feed |
| CN107279577A (en) * | 2017-07-25 | 2017-10-24 | 安徽华米生物科技有限公司 | It is a kind of to be used to prevent and treat feed of infectious bronchitis of chicken and preparation method thereof |
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| CN101006825A (en) * | 2007-01-29 | 2007-08-01 | 蔡向源 | A fowls and livestock feed capable of preventing bird flu effectively and its preparation |
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| CN101006825A (en) * | 2007-01-29 | 2007-08-01 | 蔡向源 | A fowls and livestock feed capable of preventing bird flu effectively and its preparation |
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