CN103582491B - 2型糖尿病患者中低血糖症的预防 - Google Patents

2型糖尿病患者中低血糖症的预防 Download PDF

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Publication number
CN103582491B
CN103582491B CN201280026545.9A CN201280026545A CN103582491B CN 103582491 B CN103582491 B CN 103582491B CN 201280026545 A CN201280026545 A CN 201280026545A CN 103582491 B CN103582491 B CN 103582491B
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treatment
patient
hypoglycemia
purposes
lixisenatide
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Chinese (zh)
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CN103582491A (zh
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G.博卡
L.西尔维斯特雷
P.米奥塞克
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Sanofi Aventis Deutschland GmbH
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Sanofi Aventis Deutschland GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
CN201280026545.9A 2011-03-29 2012-03-29 2型糖尿病患者中低血糖症的预防 Active CN103582491B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11160270.2 2011-03-29
EP11160270 2011-03-29
PCT/EP2012/055660 WO2012130955A1 (en) 2011-03-29 2012-03-29 Prevention of hypoglycaemia in diabetes mellitus type 2 patients

Publications (2)

Publication Number Publication Date
CN103582491A CN103582491A (zh) 2014-02-12
CN103582491B true CN103582491B (zh) 2016-12-07

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CN201280026545.9A Active CN103582491B (zh) 2011-03-29 2012-03-29 2型糖尿病患者中低血糖症的预防

Country Status (20)

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US (2) US20120277147A1 (es)
EP (1) EP2691109B1 (es)
JP (1) JP6410600B2 (es)
KR (1) KR20140033030A (es)
CN (1) CN103582491B (es)
AU (1) AU2012234180B2 (es)
BR (1) BR112013024973B1 (es)
CA (1) CA2830811A1 (es)
CY (1) CY1116799T1 (es)
DK (1) DK2691109T3 (es)
ES (1) ES2549955T3 (es)
HK (1) HK1192725A1 (es)
HR (1) HRP20151087T1 (es)
HU (1) HUE025716T2 (es)
MX (1) MX336657B (es)
PL (1) PL2691109T3 (es)
PT (1) PT2691109E (es)
RU (1) RU2583134C2 (es)
SI (1) SI2691109T1 (es)
WO (1) WO2012130955A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010043566A2 (de) 2008-10-17 2010-04-22 Sanofi-Aventis Deutschland Gmbh Kombination von einem insulin und einem glp-1-agonisten
US9707176B2 (en) 2009-11-13 2017-07-18 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist and methionine
ES2855146T3 (es) 2009-11-13 2021-09-23 Sanofi Aventis Deutschland Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (pt) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Acelerómetro pendular
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TWI780236B (zh) 2013-02-04 2022-10-11 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
SG11201604706TA (en) 2014-01-09 2016-07-28 Sanofi Sa Stabilized pharmaceutical formulations of insulin aspart
CN112957455A (zh) 2014-01-09 2021-06-15 赛诺菲 胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂
WO2015104311A1 (en) 2014-01-09 2015-07-16 Sanofi Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
WO2020112253A2 (en) * 2018-10-16 2020-06-04 The Board Of Regents Of The University Of Oklahoma Uses of glucagon-like peptide-1 receptor agonists for treating trauma-induced hearing loss

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1413582A (zh) * 2002-11-29 2003-04-30 贵州圣济堂制药有限公司 盐酸二甲双胍肠溶片及其制备方法
WO2007001150A2 (en) * 2005-06-27 2007-01-04 Jae-Kwan Hwang Method for preventing and treating conditions mediated by ppar using macelignan

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1076066A1 (en) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptides for lowering blood glucose levels
SK287810B6 (sk) * 1999-11-03 2011-10-04 Bristol-Myers Squibb Company Farmaceutický prostriedok obsahujúci nízkodávkovú kombináciu metformínu a glyburidu
PT1928499E (pt) * 2005-09-20 2011-09-09 Novartis Ag Utilização de um inibidor da dpp-iv para reduzir eventos hipoglicémicos
WO2010043566A2 (de) * 2008-10-17 2010-04-22 Sanofi-Aventis Deutschland Gmbh Kombination von einem insulin und einem glp-1-agonisten

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1413582A (zh) * 2002-11-29 2003-04-30 贵州圣济堂制药有限公司 盐酸二甲双胍肠溶片及其制备方法
WO2007001150A2 (en) * 2005-06-27 2007-01-04 Jae-Kwan Hwang Method for preventing and treating conditions mediated by ppar using macelignan

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Lixisenatide，a novel GLP-1 receptor agonist for the treatment of type2 diabetes mellitus;Christensen et al;《I Drugs》;20090831;第12卷(第8期);摘要，第505页右栏倒数第1-2段，第506页左栏倒数第1-3段，第506页右栏，第507页左栏，第508页左栏，第509页右栏倒数第1段，第510页左栏第1段 *

Also Published As

Publication number Publication date
RU2013148014A (ru) 2015-05-10
ES2549955T3 (es) 2015-11-03
SI2691109T1 (sl) 2015-11-30
CN103582491A (zh) 2014-02-12
CY1116799T1 (el) 2017-03-15
JP6410600B2 (ja) 2018-10-24
PT2691109E (pt) 2015-10-30
WO2012130955A1 (en) 2012-10-04
HUE025716T2 (en) 2016-04-28
CA2830811A1 (en) 2012-10-04
HK1192725A1 (en) 2014-08-29
US20120277147A1 (en) 2012-11-01
DK2691109T3 (en) 2015-10-19
PL2691109T3 (pl) 2015-12-31
MX336657B (es) 2016-01-27
US20180000902A1 (en) 2018-01-04
MX2013011174A (es) 2013-11-01
AU2012234180B2 (en) 2017-02-16
EP2691109B1 (en) 2015-07-15
KR20140033030A (ko) 2014-03-17
JP2014514289A (ja) 2014-06-19
HRP20151087T1 (hr) 2015-11-20
AU2012234180A1 (en) 2013-10-17
EP2691109A1 (en) 2014-02-05
BR112013024973A2 (pt) 2016-08-30
BR112013024973B1 (pt) 2022-06-07
RU2583134C2 (ru) 2016-05-10

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