CN103554143B - 1‑氨基‑2‑环丁基乙基硼酸衍生物 - Google Patents
1‑氨基‑2‑环丁基乙基硼酸衍生物 Download PDFInfo
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- CN103554143B CN103554143B CN201310475757.1A CN201310475757A CN103554143B CN 103554143 B CN103554143 B CN 103554143B CN 201310475757 A CN201310475757 A CN 201310475757A CN 103554143 B CN103554143 B CN 103554143B
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- 125000006168 tricyclic group Chemical group 0.000 description 1
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Classifications
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- C07K—PEPTIDES
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- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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Landscapes
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Abstract
Description
时间 | A[%] | B[%] | 流速[ml/min] |
0.0 | 95.0 | 5.0 | 1.0 |
7.5 | 0.0 | 100.0 | 1.0 |
9.8 | 0.0 | 100.0 | 1.0 |
9.8 | 95.0 | 5.0 | 1.0 |
10.0 | 95.0 | 5.0 | 1.0 |
Claims (10)
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CN (2) | CN103554143B (zh) |
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EP3090737A1 (en) | 2008-10-21 | 2016-11-09 | Onyx Therapeutics, Inc. | Combination therapy with peptide epoxyketones |
TWI504598B (zh) | 2009-03-20 | 2015-10-21 | Onyx Therapeutics Inc | 結晶性三肽環氧酮蛋白酶抑制劑 |
US8853147B2 (en) | 2009-11-13 | 2014-10-07 | Onyx Therapeutics, Inc. | Use of peptide epoxyketones for metastasis suppression |
MA34133B1 (fr) * | 2010-03-01 | 2013-04-03 | Onyx Therapeutics Inc | Composes pour inhibiteurs de l'immunoproteasome |
AR080863A1 (es) | 2010-03-31 | 2012-05-16 | Millennium Pharm Inc | Derivados del acido1-amino-2-ciclopropiletilboronico, composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del cancer. |
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JP6397765B2 (ja) | 2011-11-11 | 2018-09-26 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | プロテアソーム阻害剤に応答するバイオマーカー |
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