Summary of the invention
Based on this, be necessary to provide a kind of specific protein analyzer sampling needle cleaning method that improves the sampling needle cleaning quality.
Be necessary to provide a kind of specific protein analyzer sampling needle cleaning device that improves the sampling needle cleaning quality simultaneously.
A kind of specific protein analyzer sampling needle cleaning method comprises:
Outer wall washing: the swab liquid feed valve of controlling swab inlet feed liquor is opened, and the inlet by swab injects cleaning fluid in the swab inner chamber, and clean and run through by the sampling needle of swab inner chamber, and by the liquid outlet effluent discharge of swab;
Inner wall washing: sampling needle is drawn cleaning fluid and is carried out application of sample, after application of sample has moved, drives the liquid of getting rid of in the sampling needle inner chamber, cleans the sampling needle inwall;
Needle point cleans: the inlet by service sink injects cleaning fluid to service sink, cleans the part that is placed in the service sink inner chamber on sampling needle.
Described needle point also comprises before cleaning: drive sampling needle rotate and move up and down to service sink.
In a preferred embodiment, described outer wall washing also comprises: sampling needle moves up and down along swab, cleans the sampling needle diverse location; The inlet of described swab is arranged on the sidewall of described swab.
In a preferred embodiment, the liquid outlet of described swab is arranged on the sidewall of described swab; Described outer wall washing also comprises: utilize negative pressure from the liquid outlet of described swab by the liquid sucking-off described swab inner chamber.
In a preferred embodiment, the inlet of described service sink is arranged on the sidewall of this service sink, and the liquid outlet of described service sink is arranged on the bottom of this service sink; Described service sink is discharged liquid from the liquid outlet of bottom.
In a preferred embodiment, described outer wall washing also comprises: dynamical element drives and cleans the outer injectors action, controlling the swab liquid feed valve opens, inject cleaning fluid by inlet on the swab sidewall to the swab inner chamber, cleaning runs through by the sampling needle of swab inner chamber, and by the liquid outlet effluent discharge of swab;
Described inner wall washing also comprises: control sampling needle absorption cleaning fluid and carry out application of sample, after application of sample has moved, controlling sampling needle rotates and drops to service sink, controlling the sampling needle draining valve opens, order about sampling needle and discharge the liquid in its inner chamber, to clean the inwall of sampling needle, and liquid is entered to service sink;
Described needle point cleans and also comprises: control the service sink liquid feed valve and open, the inlet by the service sink sidewall injects cleaning fluid in the inner chamber of service sink, cleans the part that sampling needle is placed in service sink.
A kind of specific protein analyzer sampling needle cleaning device comprises: frame, be arranged on sampling needle rocker arm assembly on frame, be arranged on described rocker arm assembly and by this rocker arm assembly drive elevating movement and the hollow sampling needle rotatablely moved, be arranged on described rocker arm assembly and be set on described sampling needle and with the swab of this sampling needle synchronous rotary motion, and and the service sink of described sampling needle relative set; The tubular elements that described swab is hollow structure; Described sampling needle one end is fixed on described rocker arm assembly, and its other end runs through the hollow hole of described swab and along the hollow hole oscilaltion campaign of this swab; The hollow hole of described swab and described sampling needle are suitable, are provided with inlet and liquid outlet on the sidewall of described swab.
In a preferred embodiment, described rocker arm assembly comprises: the supporting plate that rocking arm, the transmission component be connected with described sampling needle power transmission shaft, the described transmission component of sampling needle power transmission shaft, the beam type that is connected with described sampling needle power transmission shaft connects and fix described swab; Described supporting plate and described synchronous rocker rotatablely move.
In a preferred embodiment, described transmission component comprises: the supporting plate anchor post assembly of fixing described supporting plate, the lifter plate be slidably connected with described sampling needle power transmission shaft, carry described and anchor post assembly and lifter plate and drive this anchor post assembly and rotating disk that lifter plate rotatablely moves, and drive driving force member and the dynamical element of turntable rotation motion; On described lifter plate, be provided with so that described sampling needle power transmission shaft, along the chute of its oscilaltion campaign, is provided with the position sensor of responding to described sampling needle position of rotation on described rotating disk.
In a preferred embodiment, be provided with the cavity volume of accommodating described sampling needle tip portion on described service sink; Be provided with inlet on the sidewall of described service sink, its bottom is provided with liquid outlet; Described sampling needle comprises: cannula body, be set in sleeve on cannula body, be arranged on the insulation sleeve between described sleeve and described cannula body.Described service sink up/down perforation also forms the inner chamber of accommodating sampling needle.
In a preferred embodiment, also comprise: liquid-way system, described liquid-way system comprises: hydraulic pump, the hydraulic pressure arm be connected with described hydraulic pump, the swab liquid feed valve be connected with the feed liquor oral fluid road of described swab, the service sink liquid feed valve be connected with the feed liquor oral fluid road of described service sink, the sampling needle-valve be connected with the intracavity liquid road of described sampling needle; Described swab liquid feed valve, service sink liquid feed valve, sampling needle-valve are linked in described hydraulic pump by the hydraulic pressure arm, be provided with between described sampling needle-valve and described sampling needle and inhale the sample syringe, the liquid outlet of described swab is linked into by the swab liquid valve in the vacuum tank that produces negative pressure, and described swab liquid feed valve also is connected with to drive controls the cleaning syringe that this swab liquid feed valve opens to clean described sampling needle.
Above-mentioned specific protein analyzer sampling needle cleaning device and method, clean the sampling needle that is placed in the swab inner chamber is cleaned with the outer wall to sampling needle by swab, and the inner chamber oscilaltion campaign formed along the hollow hole of swab by sampling needle is with comprehensive cleaning sampling needle, inhale sample and stock layout to clean the sampling needle inwall by sampling needle, clean by service sink the part that sampling needle is placed in the inner chamber of service sink, to clean the part that on sampling needle, swab can not clean or can not clean fully, realize thoroughly cleaning the sampling needle inside and outside wall.
The specific embodiment
As shown in Figures 1 to 7, the specific protein analyzer sampling needle cleaning device 100 of one embodiment of the invention, comprise: frame 20, be arranged on the sampling needle rocker arm assembly 40 on frame 20, the hollow sampling needle 60 that is arranged on rocker arm assembly 40 and drives elevating movement and rotatablely move by this rocker arm assembly, be arranged on rocker arm assembly 40 and be set on sampling needle 60 and with the swab 80 of these sampling needle 60 synchronous rotaries motions, and and the service sink 90 of sampling needle 60 relative set.
Further, the tubular elements that the swab 80 of the present embodiment is hollow structure, for sampling needle 60 connect through.
Further, sampling needle 60 1 ends of the present embodiment are fixed on rocker arm assembly 40, and its other end runs through the hollow hole of swab 80 and along the hollow hole oscilaltion campaign of this swab 80.
Further, the hollow hole of the swab 80 of the present embodiment is that inner chamber and sampling needle 60 are suitable.Be provided with inlet 82 on the sidewall of swab 80, reach liquid outlet 84.The sealed bottom of swab 80.
Further, the rocker arm assembly 40 of the present embodiment comprises: the sampling needle power transmission shaft 42 that drives sampling needle 60 oscilaltion campaigns, with sampling needle 60 power transmission shafts, be connected and the Rocker arm 44 of the cantilever beam structure of fixed sample pin 60, the transmission component 46 be connected with sampling needle power transmission shaft 42, be connected with transmission component 46, and the fixing supporting plate 48 of swab 80.Supporting plate 48 and Rocker arm 44 synchronous rotary motions.
Further, transmission component 46 comprises: the anchor post assembly 462 of fixed support plate 48, the lifter plate 464 be slidably connected with sampling needle power transmission shaft 42, carrying anchor post assembly 462 and lifter plate 464 also drives this anchor post assembly 462 and rotating disk 466 that lifter plate 464 rotatablely moves, and the driving force member and the dynamical element 468 that drive rotating disk 466 to rotatablely move.
On the lifter plate 464 of the present embodiment, be provided with so that sampling needle power transmission shaft 42 along the chute 4642 of its oscilaltion campaign.
Further, be provided with the position sensor 463 of induction sampling needle 60 position of rotation on the rotating disk 466 of the present embodiment.
Further, be provided with the cavity volume 92 of accommodating sampling needle 60 tip portion on the service sink 90 of the present embodiment.Be provided with inlet 94 on the sidewall of service sink 90, its bottom is provided with liquid outlet 96.
As shown in Figure 6, further, the sampling needle 60 of the present embodiment arranges layer minute and comprises inside and outside complying with: the cannula body 62 of hollow structure, be set in sleeve 64 on cannula body 62, be arranged on the insulation sleeve 66 between sleeve 64 and cannula body 62.
Further, for convenient, install and location, facilitate and be connected with liquid-way system simultaneously, the sampling needle 60 of the present embodiment preferably is set to turn shape, comprising: the operate portions 604 of the straight tube-like that liquid road connecting portion 602, Ji Yuye road connecting portion 602 connect.Liquid road connecting portion 602 is connected to form and turns shape with operate portions 604.Further, the straight tube-like operate portions 604 of the sampling needle of the present embodiment comprises: the cannula body 62 of hollow structure, be set in sleeve 64 on cannula body 62, be arranged on the insulation sleeve 66 between sleeve 64 and cannula body 62.On the cannula body 62 of the operate portions 604 of straight tube-like, relatively the other end of needle point 600 is arranged with guide pin bushing 65.Guide pin bushing 65 all is set on cannula body 62 with sleeve 64, and in abutting connection with arranging.Guide pin bushing 65 guiding sampling needles 60 coordinate installation with Rocker arm 44.
Further, the other end of the operate portions 604 relative needle points 600 of the straight tube-like of the present embodiment also be provided with the sampling needle limited post 61 be set on insulation sleeve 66 in exhausted guide pin bushing 65 tops.Sampling needle limited post 61 is for limit mounting sampling needle 60.Also overlap and be provided with sample needle insulation sleeve 67 on the insulation sleeve 66 of operate portions 604, in sampling needle limited post 61 belows and in being close on sampling needle limited post 61 positions.Also be provided with sample needle catch 69 on the operate portions 604 of straight tube-like.The present embodiment Ye road connecting portion 602 comprises: the cannula body 62 of hollow structure.The sampling needle 60 of the present embodiment is preferably inside and outside double sheathed needle, is provided with inductor on the inner tube wall of sampling needle to carry out level detection, and makes it have collision prevention function by inside and outside double sheathed needle structure.
As shown in Figure 7, further, the specific protein analyzer sampling needle cleaning device 100 of the present embodiment also comprises: liquid-way system 50.Liquid-way system 50 comprises: hydraulic pump 52, the hydraulic pressure arm 54 be connected with hydraulic pump 52, the swab liquid feed valve SV4 be connected with the inlet 82Ye road of swab 80, the service sink liquid feed valve SV2 be connected with the inlet 94Ye road of service sink 90, the sampling needle-valve SV3 be connected with the intracavity liquid road of sampling needle 60.
Further, the swab liquid feed valve SV4 of the present embodiment, service sink liquid feed valve SV2, sampling needle-valve SV3 are linked in hydraulic pump 52 by hydraulic pressure arm 54.
Further, for the ease of inhaling sample, be provided with between the sampling needle-valve SV3 of the present embodiment and sampling needle 60 and inhale sample syringe 70.
Further, for the ease of the liquid by swab 80, discharge, the liquid outlet 84 of swab 80 is connected to by swab liquid valve SV6 so that the liquid outlet 84 of this swab 80 produces in the vacuum tank assembly of negative pressure.The vacuum tank assembly comprises: vacuum tank 71 and the vavuum pump 73 be connected with vacuum tank 71.
Further, the swab liquid feed valve SV4 of the present embodiment also is connected with the cleaning syringe 74 that drives this swab liquid feed valve SV4 to open to clean sampling needle 60 outer walls.
The protein analyzer sampling needle cleaning device 100 that the present invention proposes, the sidewall that adopts swab 80 to clean cavity is provided with two holes, and be respectively inlet 82, reach liquid outlet 84, and its sealed bottom.Sampling needle 60 can run through swab 80 and move up and down, and swab 80 is positioned at the initial bit below of sampling needle 60, and the bottom needle point 600 of sampling needle 60 exposes swab 80.
Service sink 90 communicates up and down, and side has inlet 94, and liquid outlet 96 is arranged on service sink 90 bottoms, and the waste liquid after cleaning is discharged by bottom liquid outlet 90.
Sampling needle 60 is connected with sampling needle power transmission shaft 42 by Rocker arm 44, and sampling needle power transmission shaft 42 can stretch up and down, thereby drive Rocker arm 44 and the sampling needle 60 that is fixed on Rocker arm 44 move up and down.The bottom position of sampling needle power transmission shaft 42 arranges the fixedly supporting plate 48 of swab 80, supporting plate 48 and Rocker arm 44 synchronous rotary motions.
When sampling needle 60 passes through swab 80, on the cleaning syringe 74 of driven by motor cleaning sampling needle outer wall, draw, swab liquid feed valve SV4 opens, inlet 82 by swab 80 is squeezed into cleaning fluid, the negative pressure that liquid outlet utilizes vavuum pump 73 to produce is by the waste liquid sucking-off, this process is mainly used in cleaning the outer wall of sampling needle 60, is used in particular for the cleaning of whole blood sample.After sampling needle 60 completes the application of sample action, rotate and drop to service sink 90, sampling needle-valve SV3 opens, and cleaning fluid is got in sampling needle 60 inside, cleans the inwall of sampling needle 60, and waste liquid is entered in service sink 90, and this process is mainly used to clean the inwall of sampling needle.Simultaneously, service sink liquid feed valve SV2 valve is opened, inject cleaning fluid from the inlet 94 of service sink 90 sides to service sink 90, for cleaning the needle point place outer wall of the sampling needle 60 that sampling needle swab 80 can not clean or can not clean to fully, realize thoroughly clean to the sampling needle inside and outside wall.
The protein analyzer sampling needle cleaning device 100 that the present invention proposes can be realized the thorough cleaning to the inside and outside wall of sampling needle 60.The humoral specimens such as whole blood, blood plasma, serum, cerebrospinal fluid are all had to good cleaning performance.Adopt the method for sampling needle inside and outside wall synchronous cleaning, adopt swab 80 cleanings, reach two kinds of cleaning method combinations of service sink 90 cleanings, realize thoroughly cleaning multiple sample.
As shown in Figure 8, the specific protein analyzer sampling needle cleaning method of one embodiment of the invention comprises:
Step S301, outer wall washing: the swab liquid feed valve of controlling swab inlet feed liquor is opened, and the inlet by swab injects cleaning fluid in swab, cleans the sampling needle in swab, and by the liquid outlet effluent discharge of swab;
Step S303, inner wall washing: sampling needle is drawn cleaning fluid, and drives the liquid of discharging in the sampling needle inner chamber, to clean sampling needle;
Step S305, needle point cleans: drive sampling needle to service sink, the inlet by service sink injects cleaning fluid to service sink, cleans sampling needle.
Further, the step S301 of the present embodiment, outer wall washing also comprises: sampling needle 60 moves along the swab oscilaltion, cleans the diverse location of sampling needle 60 outer walls.
Further, the inlet 82 of the swab 80 of the present embodiment is arranged on the sidewall of swab 80.
Further, the liquid outlet 84 of the swab 80 of the present embodiment also is arranged on the sidewall of swab.Further, the step S301 of the present embodiment, outer wall washing also comprises:: utilize negative pressure from the liquid outlet 84 of swab 80 by liquid as the waste liquid sucking-off.
Further, the inlet 92 of the service sink 90 of the present embodiment is arranged on the sidewall of this service sink 80.The inlet 92 of service sink is by service sink liquid feed valve SV2, be connected to hydraulic pump 52 through hydraulic pressure arm 54.
Further, the liquid outlet 94 of the service sink 90 of the present embodiment is arranged on the bottom of this service sink 90.Service sink 90 is discharged liquid from the liquid outlet 94 of bottom.The liquid outlet 94 of service sink 90 is connected in sewer pipe 77 and carries out discharge opeing.
As shown in Figure 9, the specific protein analyzer sampling needle cleaning method of one embodiment of the present invention comprises:
Step S501, outer wall washing: dynamical element drives and cleans syringe 74 actions, control and drive swab liquid feed valve SV4 to open, inject cleaning fluid by inlet 82 on swab 80 sidewalls in the inner chamber of swab 80, be applied in the sampling needle 60 in the inner chamber of swab 80 with cleaning, after cleaning, by the liquid outlet 84 of swab 80, discharge liquid.Dynamical element is preferably motor.Preferably, driven by motor is cleaned on syringe 74 and is drawn, and opens swab liquid feed valve SV4.Swab 80 sealed bottoms.
Step S503, inner wall washing: the sampling needle application of sample is drawn cleaning fluid, and sampling needle rotates and moves up and down to service sink 90 after completing the application of sample action, controls sampling needle-valve SV3 and opens, and orders about sampling needle 60 inner chambers and discharges cleaning fluid, to clean the inwall of sampling needle 60; And the waste liquid after cleaning is entered in service sink 90.
Step S505, needle point cleans: control and open service sink liquid feed valve SV2, the inlet 92 arranged by service sink 90 sides injects cleaning fluid to service sink 90, cleans sampling needle.In the needle point cleaning step, mainly clean the needle point place outer wall of the sampling needle 60 that in swab 80 cleanings, can not clean or can not clean to fully, realize thoroughly cleaning the sampling needle inside and outside wall.
Further, the liquid outlet 94 of the service sink 90 of the present embodiment is arranged on the bottom of this service sink 90.Service sink 90 is discharged liquid from the liquid outlet 94 of bottom.The liquid outlet 94 of service sink 90 is connected in sewer pipe 77 and carries out discharge opeing.
The above embodiment has only expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.