CN109030846B - Sample analyzer and sample suction needle movement control method thereof - Google Patents
Sample analyzer and sample suction needle movement control method thereof Download PDFInfo
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- CN109030846B CN109030846B CN201710433328.6A CN201710433328A CN109030846B CN 109030846 B CN109030846 B CN 109030846B CN 201710433328 A CN201710433328 A CN 201710433328A CN 109030846 B CN109030846 B CN 109030846B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
Abstract
The invention relates to a sample analyzer and a sample suction needle movement control method thereof. The sample analyzer comprises a sampling structure, a sample transporting structure and a controller, wherein the sampling structure comprises a sample sucking needle and a transfer assembly, the sample sucking needle is arranged on the transfer assembly, and the transfer assembly can move the sample sucking needle along a first direction and a second direction; the sample transport structure is capable of transporting the sample container to a first sampling location; the controller is used for controlling the transferring assembly; the sample sucking needle can suck the sample in the sample container transferred to the first sampling position by the sample conveying structure, and can suck the sample in the handheld sample container positioned at the second sampling position; in the process that the controller controls the transfer assembly to move the sample sucking needle to the second sampling position, the controller firstly controls the transfer assembly to move the sample sucking needle to the first preset position along the first direction, then moves the sample sucking needle to the second preset position along the second direction, and then moves the sample sucking needle to the second sampling position along the first direction. The sample analyzer can reduce the risk of injuring the hand when the sample suction needle descends.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a sample analyzer and a sample suction needle motion control method thereof.
Background
Conventional sample analyzers may have both automatic and open measurement modes. When the sample is measured in an open state, an operator manually places a container filled with a sample below the sample sucking needle, so that the needle head of the sample sucking needle can be immersed in the sample to suck the sample.
The automatic measuring sample sucking needle needs to pierce the sealing cover, so the automatic sampling device adopts a sharp-pointed needle which needs to adopt a sharp needle head. If the same spike is used for automatic measurement and open measurement, the risk of hand injury exists if the operator holds the container in the sampling position for open measurement and waits in the process of descending the spike. If the blunt needle is independently adopted for the opening measurement, different sample sucking needles are adopted for the automatic measurement and the opening measurement, and the cost is higher.
Disclosure of Invention
In view of the above, it is desirable to provide a sample analyzer that can avoid hand pricking in the open measurement mode without increasing the cost.
A sample analyzer for analyzing a sample in a sample container, the sample analyzer comprising:
the sampling structure comprises a sample sucking needle and a transfer component, wherein the sample sucking needle is arranged on the transfer component, and the transfer component can move the sample sucking needle along a first direction and a second direction;
a sample transport structure capable of transporting the sample container to a first sampling location; and
the controller is used for controlling the transfer assembly to move the sample sucking needle to the first sampling position and the second sampling position; the sample sucking needle can suck the sample in the sample container moved to the first sampling position by the sample conveying structure, and the sample sucking needle can also suck the sample in the handheld sample container positioned at the second sampling position;
in the process that the controller controls the transfer assembly to move the sample sucking needle to the second sampling position, the controller controls the transfer assembly to move the sample sucking needle to a first preset position along the forward direction of the first direction, then to move to a second preset position along the forward direction of the second direction in a safe area, and then to move to the second sampling position along the forward direction of the first direction.
In one embodiment, the sample pipetting device further comprises a protection structure, wherein the protection structure is provided with a wall surface extending along the second direction, and when the sample pipetting needle moves from the first preset position to the second preset position, the sample pipetting needle moves along the wall surface.
In one embodiment, the protection structure is provided with a groove extending along the second direction, and when the sample suction needle moves from the first preset position to the second preset position, the sample suction needle is located in the groove and moves along the groove; the wall surface is the inner wall of the groove.
In one embodiment, an open sample feeding control key is arranged on the protection structure.
In one embodiment, the cross section of the groove is in a major arc shape or a semi-circle arc shape; when the sample sucking needle moves from the first preset position to the second preset position, the sample sucking needle is positioned at the circle center of the cross section of the groove;
or the cross section of the groove is rectangular, and when the sample sucking needle moves from the first preset position to the second preset position, the sample sucking needle is positioned on a symmetrical line of the cross section of the groove, which extends along the first direction.
In one embodiment, the width of the opening of the groove facing the first direction is less than or equal to 1 cm.
In one embodiment, the transfer assembly includes a first guide part extending in a horizontal direction, a first moving member slidably coupled to the first guide part, a second guide part extending in a vertical direction, the second guide part fixedly coupled to the first moving member, and a second moving member slidably coupled to the second guide part; the sample sucking needle is fixed on the second moving part.
In one embodiment, at least one of the following is included:
the sample sucking needle is a sharp-pointed needle;
the first direction is a horizontal direction; and
the second direction is a vertical direction.
A method for controlling the movement of a sample sucking needle of a sample analyzer is used for controlling the sample analyzer, and is characterized by comprising the following steps:
the sample sucking needle moves to the first preset position along the positive direction of the first direction;
the sample sucking needle moves from the first preset position to the second preset position along the forward direction of the second direction in a safe area; and
and the sample sucking needle moves to the second sampling position from the second preset position along the forward direction of the first direction.
In one embodiment, at least one of the following is included:
the sample sucking needle moves from the second sampling position to a third preset position along the reverse direction of the second direction, and the sample sucking needle moves away from the third preset position along the reverse direction of the first direction from the third preset position;
the sample sucking needle moves to a fourth preset position along the forward direction of the first direction, and the sample sucking needle moves to the first sampling position from the fourth preset position along the forward direction of the second direction; and
the sample sucking needle is moved to the fourth preset position along the reverse direction of the second direction from the first sampling position, and the sample sucking needle is moved away from the fourth preset position along the reverse direction of the first direction from the fourth preset position.
According to the sample analyzer and the sample suction needle movement control method thereof, the first sampling position can be used as the sampling position for automatic measurement, the second sampling position can be used as the sampling position for open measurement of the handheld sample container, the same sample suction needle can move to the first sampling position and the second sampling position respectively under the control of the controller for sampling, the sample suction needle does not need to be additionally arranged, and the cost is not increased. In the open measurement process, the controller firstly controls the transfer assembly to move the sample sucking needle to a first preset position along a first direction, then to a second preset position along a second direction, and then to a second sampling position along the first direction. The second sampling position is a position that is easily reached by the hand of the operator, and the first preset position and the second preset position may be safe positions that are difficult to reach by the hand of the operator. The sample sucking needle can be translated to a first preset position, then lowered to a second preset position, and then translated to a second sampling position after being lowered. In the descending process, the hands of the operator cannot be pricked, and the risk of pricking the hands is reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings of the embodiments can be obtained according to the drawings without creative efforts.
FIG. 1 is a perspective view of a sample analyzer in one embodiment;
FIG. 2 is a perspective view of a sampling structure and a sample transport structure of the sample analyzer shown in FIG. 1;
FIG. 3 is a perspective view of a sampling structure of the sample analyzer shown in FIG. 1;
FIG. 4 is a perspective view of a sample transport structure of the sample analyzer shown in FIG. 1;
FIG. 5 is a perspective view of a protective structure of the sample analyzer of FIG. 1;
FIG. 6 is a perspective view of a protective structure and a pipette tip of the sample analyzer of FIG. 1;
FIG. 7 is a side view of the protective structure and the pipette tip of the sample analyzer of FIG. 6;
FIG. 8 is a perspective view of a protective structure of another embodiment of the sample analyzer of FIG. 1;
FIG. 9 is a flow chart illustrating a method for controlling the movement of a sample aspirating needle of a sample analyzer according to one embodiment;
FIG. 10a is a diagram showing the movement path of the tip segment in step S100 of the method shown in FIG. 9;
FIG. 10b is a diagram showing the movement path of the pipette tip section in step S200 of the method shown in FIG. 9;
FIG. 10c is a diagram showing the movement path of the pipette tip section in step S300 of the method shown in FIG. 9;
FIG. 10d is a diagram showing the movement path of the pipette tip section in step S400 of the method shown in FIG. 9;
FIG. 11 is a partial side view of the pipette tip of the method of FIG. 9 in a fourth preset position;
FIG. 12 is a partial side view of the pipette tip of the method of FIG. 9 in a first sampling position;
FIG. 13 is a flowchart of step S300 of the method of FIG. 9;
FIG. 14 is a partial side view of the pipette tip of the method of FIG. 9 in a first predetermined position;
FIG. 15 is a partial side view of the pipette tip of the method of FIG. 9 in a second predetermined position;
FIG. 16 is a partial perspective view of the pipette tip of the method of FIG. 15 in a second predetermined position;
FIG. 17 is a partial side view of the pipette tip of the method of FIG. 9 in a second sampling position;
FIG. 18 is a partial perspective view of the pipette tip of the method of FIG. 17 in a second sampling position;
FIG. 19 is a partial side view of the pipette tip of the method of FIG. 9 in a third preset position.
Detailed Description
In order to facilitate understanding of the present invention, a sample analyzer and a method for controlling the movement of a sampling needle thereof will be more fully described with reference to the accompanying drawings. The attached drawings show a preferred embodiment of the sample analyzer and the sample sucking needle motion control method thereof. However, the sample analyzer and the method for controlling the movement of the sample aspirating needle thereof can be implemented in many different forms and are not limited to the embodiments described herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the substance of the sample analyzer and its method of control of the movement of the pipette tip.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the sample analyzer and its method of control of the movement of the sample aspirating needle is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in fig. 1 and 2, a sample analyzer 10 in one embodiment is used for analyzing a sample, which may be blood, in a sample container 20. The sample analyzer 10 includes a sampling structure 100, a sample transport structure 300, and a controller, and in one embodiment, the sample analyzer 10 can further include a sample preparation device for preparing a sample into a detection sample and a detector for detecting a component in the detection sample.
Referring also to fig. 3, the sampling structure 100 includes a pipette needle 110 and a transfer assembly 120, the pipette needle 110 being disposed on the transfer assembly 120, the transfer assembly 120 being capable of moving the pipette needle 110 in a first direction and a second direction. Referring also to fig. 4, the sample transport structure 300 is capable of transporting the sample container 20 to the first sampling site. In one embodiment, the pipette tip 110 is a sharp-pointed tip that facilitates piercing of the seal cap 21 on the sample container 20. The controller is used for controlling the transfer assembly 120 to move the sample suction needle 110 to the first sampling position and the second sampling position. The pipetting needle 110 is capable of pipetting the sample in the sample container 20 moved by the sample transport structure 300 to the first sampling position, and the pipetting needle 110 is also capable of pipetting the sample in the hand-held sample container 20 located at the second sampling position.
In the process that the controller controls the transfer assembly 120 to move the sample sucking needle 110 to the second sampling position, the controller first controls the transfer assembly 120 to move the sample sucking needle 110 to the first preset position along the forward direction of the first direction, then moves to the second preset position along the forward direction of the second direction in the safety area, and then moves to the second sampling position along the forward direction of the first direction. The safe area is an area where the operator's hand is not pricked or where the risk of pricking the operator's hand is low. In an embodiment, the first direction may be a horizontal direction, and the second direction may be a vertical direction. The first direction and the second direction are both reciprocating directions, for example, the forward direction of the first direction is forward direction, the direction Y1 is shown, the reverse direction of the first direction is backward direction, the direction Y2 is shown, the forward direction of the second direction is downward direction, the direction Z2 is shown, the reverse direction of the second direction is upward direction, and the direction Z1 is shown.
The way of the sample aspirating needle 110 moving forward in the first direction to the first preset position can include various ways: firstly, the sample sucking needle 110 always moves in the positive direction of the first direction, does not stay during the movement, and directly moves to a first preset position; secondly, after moving forward along the first direction for a certain distance, the sample sucking needle 110 stops, and then continues to move forward along the first direction, so as to reach a first preset position, wherein the stopping in the moving process can be once or for multiple times; thirdly, after moving a certain distance along the forward direction of the first direction, the sample sucking needle 110 stops and changes the moving direction, for example, moves a certain distance along the forward direction of the second direction, or moves a certain distance along other directions, and then continues to move along the forward direction of the first direction, so as to reach a first preset position. In summary, the forward movement of the sample suction needle 110 to the first preset position along the first direction may be a continuous step, or a combination of multiple steps, and may be a linear movement, a polygonal movement, or a curvilinear movement. Similarly, the movement of the sample suction needle 110 to the second preset position along the forward direction of the second direction and the movement of the sample suction needle 110 to the second sampling position along the forward direction of the first direction may be a continuous step, or a combination of multiple steps, or a linear movement, or a polygonal line movement or a curvilinear movement. Similarly, in the following embodiments, moving from a certain position to another position along a certain direction may be a continuous step, or a combination of multiple steps, or may be a linear movement, or a polygonal movement or a curvilinear movement.
The first sampling position can be used as the sampling position of automatic measurement, the second sampling position can be used as the sampling position of open measurement of the handheld sample container 20, and the same sample sucking needle 110 can move to the first sampling position and the second sampling position respectively under the control of the controller for sampling without additionally arranging the sample sucking needle 110, so that the cost is not increased. In the process of opening measurement, the controller controls the transfer assembly 120 to move the sample sucking needle 110 to a first preset position along the forward direction of the first direction, then to a second preset position along the forward direction of the second direction in the safety area, and then to a second sampling position along the forward direction of the first direction. The second sampling position is a position that is easily reached by the hand of the operator, and the first preset position and the second preset position may be safe positions that are difficult to reach by the hand of the operator. The pipette tip 110 may be translated to a first predetermined position, then lowered to a second predetermined position, and then translated to a second sampling position after being lowered. In the descending process, the hands of the operator cannot be pricked, and the risk of pricking the hands is reduced.
Referring to fig. 1, the sample container 20 may be placed on the sample rack 30, and the sample transport mechanism 300 moves the sample rack 30 such that the sample container 20 is transported to the first sampling position. Referring again to fig. 4, in one embodiment, the sample transport structure 300 may include a sample rack support member 310, a sample rack in-feed assembly 320, a sample rack bi-directional transport assembly 330, and a sample rack out-feed assembly 340. The sample rack support member 310 is used to support the sample rack 30, and the sample rack 30 is moved on the sample rack support member 310 by other components. The sample rack infeed assembly 320 feeds the sample rack 30 to a station of the sample rack bi-directional transport assembly 330. The sample rack bi-directional transport assembly 330 is capable of moving the sample rack 30 bi-directionally, in the X1 direction and in the X2 direction, to bring the sample container 20 to the first sampling position. The sample rack outfeed assembly 340 is used to remove the sample rack 30 from the station of the sample rack bidirectional transport assembly 330.
Referring also to fig. 5-7, in one embodiment, the sample analyzer 10 further includes a protective structure 500, the protective structure 500 having a wall 510 extending in a second direction, the pipette tip 110 moving along the wall 510 when the pipette tip 110 moves from the first predetermined position to the second predetermined position. Since the operator's hand is generally not too close to the protective structure 500, lowering the pipette tip 110 along the wall 510 further reduces the risk of puncture. In one embodiment, the location near wall 510 is a region with a lower risk of pricking the operator's hand, i.e., a safe region.
In an embodiment, the protection structure 500 is formed with a groove 520 extending along the second direction, and when the sample-sucking needle 110 moves from the first preset position to the second preset position, the sample-sucking needle 110 is located in the groove 520 and moves along the groove 520. Wall 510 is the inner wall of groove 520. The pipette tip 110 is positioned in the recess 520 and is not accessible, further reducing the risk of puncture. In one embodiment, the width of the opening of the groove 520 facing the first direction is less than or equal to 1cm, the width of 1cm is approximately equal to the width of the adult index finger, and the width of the opening of the groove 520 is less than the width of the adult index finger, so as to prevent fingers from extending into the groove 520. Of course, in other embodiments, the groove 520 may function to alert the operator not to place a finger in the groove 520 even though the width of the opening of the groove 520 is greater than the width of an adult's index finger. In the embodiment where the wall 510 is an inner wall of the groove 520, the position in the groove 520 is an area where the operator's hand will not be pricked, i.e. a safety area.
In one embodiment, the cross-section of the groove 520 may be a major arc segment or a semi-circular segment. Further, in one embodiment, when the pipetting needle 110 moves from the first preset position to the second preset position, the pipetting needle 110 is located at the center of the cross section of the groove 520. In other embodiments, the pipetting needle 110 may not be located at the center of the circle, as long as the pipetting needle 110 does not contact the wall 510.
Referring also to FIG. 8, in another embodiment, the cross-section of the groove 520 may be rectangular, and when the pipetting needle 110 moves from the first preset position to the second preset position, the pipetting needle 110 is located on a symmetry line of the cross-section of the groove 520 extending along the first direction. In other embodiments, the pipetting needle 110 may not be located on the symmetry line, as long as the pipetting needle 110 does not contact the wall surface 510. The cross section of the groove 520 may be a part of other shapes such as an ellipse, a triangle, a pentagon, etc., so that a semi-closed space is formed inside the groove 520. In one embodiment, the protection structure 500 is provided with an open sample control button 530. The protection structure 500 may serve as a panel for the open inlet control button 530.
Referring to fig. 3 again, in one embodiment, the transferring assembly 120 includes a first guiding component 121, a first moving member 122, a second guiding component 123 and a second moving member 124, the first guiding component 121 extends along a horizontal direction, the first moving member 122 is slidably connected to the first guiding component 121, the second guiding component 123 extends along a vertical direction, the second guiding component 123 is fixedly connected to the first moving member 122, and the second moving member 124 is slidably connected to the second guiding component 123. The pipetting needle 110 is fixed to the second displacement member 124. In an embodiment, the first guide member 121 and the second guide member 123 may be a guide rod, a guide rail, or a linear slide rail.
In one embodiment, the sample sucking and transferring assembly 120 further includes a screw 125, and the screw 125 is fixed on the first moving member 122. The second moving member 124 includes a mounting portion 124a and a nut 124b, the mounting portion 124a is slidably connected to the second guiding member 123, a mounting hole 124c and a positioning slot 124d are formed in the mounting portion 124a, the mounting hole 124c penetrates through two sides of the positioning slot 124d, the screw 125 is mounted in the mounting hole 124c, the nut 124b is sleeved on the screw 125 and is in threaded connection with the screw 125, and the nut 124b is located in the positioning slot 124 d.
In one embodiment, the sample sucking and transferring assembly 120 may further include a first driver 126, two synchronizing wheels 127, and a timing belt 128, where the first driver 126 may be a stepping motor, the number of the synchronizing wheels 127 is two, the first driver 126 drives one of the synchronizing wheels 127 to rotate, the timing belt 128 surrounds the two synchronizing wheels 127, and the synchronizing wheels 127 rotate to drive the timing belt 128 to move. The timing belt 128 is connected to the first moving member 122 to drive the first moving member 122 to slide on the first guide part 121. The sample aspirating and transferring assembly 120 may further include a second driver 129 for driving the screw 125 to rotate, and the second driver 129 may also be a stepping motor.
In an embodiment, the sample sucking and transferring assembly 120 may further include a first sensor 131 and a first sensing piece 132, the first sensor 131 is directly or indirectly connected to the first guiding member 121, the first sensor 131 is located at one end of the first guiding member 121, the first sensing piece 132 is fixed on the first moving member 122, and the first sensor 131 and the first sensing piece 132 cooperate to sense whether the first moving member 122 is at the initial position. In an embodiment, the sample sucking and transferring assembly 120 may further include a second sensor 133 and a second sensing piece, the second sensor 133 is fixed on the first moving member 122, the second sensing piece is fixed on the mounting portion 124a of the second moving member 124, and the second sensor 133 and the second sensing piece cooperate to sense whether the second moving member 124 is at the initial position.
As shown in fig. 9, a method for controlling the movement of the pipette tip 110 of the sample analyzer 10 in one embodiment is used for controlling the sample analyzer 10 shown in fig. 1 to 8, and the method includes the following steps:
and S100, automatically measuring sampling trip movement. Referring to FIG. 10a, FIG. 10a is a diagram illustrating the movement path of the head of the pipetting needle 110 in step S100. Specifically, referring to fig. 11 and 12 together, in an embodiment, in step S100, the pipette tip 110 moves to the fourth preset bit P4 along the positive direction of the first direction, and the pipette tip 110 moves to the first sampling bit Q1 along the positive direction of the second direction from the fourth preset bit P4. In an embodiment where the first direction may be a horizontal direction and the second direction may be a vertical direction, the fourth preset bit P4 may be located above the first sampling bit Q1.
And S200, automatically measuring the sampling return motion. Referring to FIG. 10b, FIG. 10b is a diagram illustrating the movement path of the head of the pipetting needle 110 in step S200. Specifically, in step S200, the pipette tip 110 is moved from the first sampling bit Q1 to the fourth preset bit P4 in the reverse direction of the second direction, and the pipette tip 110 is moved from the fourth preset bit P4 in the reverse direction of the first direction by the fourth preset bit P4.
And S300, opening the sampling trip motion of measurement. Referring to FIG. 10c, FIG. 10c is a diagram illustrating the movement path of the head of the pipetting needle 110 in step S300. Referring to fig. 13, step S300 specifically includes the following steps:
s310, the sample suction needle 110 moves to a first preset position P1 along the positive direction of the first direction. The pipette tip 110 is in the first predetermined position P1, as shown in FIG. 14. In one embodiment, the manner of moving the pipette tip 110 to the first preset position P1 along the positive direction of the first direction may include several ways: firstly, the sample sucking needle 110 always moves in the positive direction of the first direction, does not stay during the movement, and directly moves to the first preset position P1; secondly, after moving forward along the first direction for a certain distance, the sample sucking needle 110 stops, and then continues to move forward along the first direction, so as to reach the first preset position P1, wherein the stopping in the moving process can be once or multiple times; thirdly, the sample suction needle 110 stops after moving a certain distance in the forward direction of the first direction, and changes the moving direction, for example, moves a certain distance in the forward direction of the second direction, or moves a certain distance in other directions, and then continues to move in the forward direction of the first direction, so as to reach the first preset position P1, and the stopping and changing of the moving direction in the moving process can be performed once or for multiple times. In summary, the movement of the sample aspirating needle 110 to the first preset position P1 along the forward direction of the first direction may be a continuous step, or a combination of multiple steps, and may be a linear movement, a polygonal movement, or a curvilinear movement. Similarly, in the following embodiments, moving from a certain position to another position along a certain direction may be a continuous step, or a combination of multiple steps, or may be a linear movement, or a polygonal movement or a curvilinear movement.
S320, the sample sucking needle 110 moves from the first preset position P1 to the second preset position P2 along the positive direction of the second direction in the safety area. The sample aspirating needle 110 is in the second preset position P2, as shown in fig. 15 and 16. In an embodiment where the first direction may be a horizontal direction and the second direction may be a vertical direction, the second preset position P2 may be located below the first preset position P1.
At S330, the sample aspirating needle 110 is moved from the second preset bit P2 to the second sampling bit Q2 along the positive direction of the first direction. The sample aspirating needle 110 is in the second sampling position Q2, as shown in fig. 17 and 18.
The second sampling position Q2 may be a sampling position for an open measurement of the hand-held sample container 20, the second sampling position Q2 may be a position easily reached by the hand of the operator, and the first preset position P1 and the second preset position P2 may be safe positions difficult to reach by the hand of the operator. The pipette tip 110 may first translate to the first predetermined position P1, then descend to the second predetermined position P2, and then translate to the second sampling position Q2. In the descending process, the hands of the operator cannot be pricked, and the risk of pricking the hands is reduced.
And S400, opening the sampling return motion of the measurement. Referring to FIG. 10d, FIG. 10d is a diagram illustrating the movement path of the head of the pipetting needle 110 in step S400. Specifically, referring to fig. 19, in step S400, in one embodiment, the pipette tip 110 is moved from the second sampling position Q2 to the third preset position P3 in the reverse direction of the second direction, and the pipette tip 110 is moved from the third preset position P3 in the reverse direction of the first direction by the third preset position P3.
In the steps S100 to S400, the controller controls the transfer module 120, and the transfer module 120 drives the sample aspirating needle 110 to move. The first sampling level Q1 may be used as a sampling level for automatic measurement, steps S100 and S200 as a motion mode in automatic measurement mode, the second sampling level Q2 as a sampling level for open measurement of the hand-held sample container 20, and steps S300 and S400 as a motion mode in open measurement mode. The same sample sucking needle 110 can move to the first sampling position Q1 and the second sampling position Q2 respectively under the control of the controller for sampling, and the sample sucking needle 110 does not need to be arranged additionally, so that the cost is not increased.
Steps S100 and S200 may be performed before or after steps S300 and S400 as necessary. Step S100 and step S200 may be performed once or repeatedly as needed, and step S300 and step S400 may also be performed once or repeatedly as needed.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (10)
1. A sample analyzer for analyzing a sample in a sample container, the sample analyzer comprising:
the sampling structure comprises a sample sucking needle and a transfer component, wherein the sample sucking needle is arranged on the transfer component, and the transfer component can move the sample sucking needle along a first direction and a second direction;
a sample transport structure capable of transporting the sample container to a first sampling location; and
the controller is used for controlling the transfer assembly to move the sample sucking needle to the first sampling position and the second sampling position; the sample sucking needle can suck the sample in the sample container moved to the first sampling position by the sample conveying structure, and the sample sucking needle can also suck the sample in the handheld sample container positioned at the second sampling position;
in the process that the controller controls the transfer assembly to move the sample sucking needle to the second sampling position, the controller controls the transfer assembly to move the sample sucking needle to a first preset position along the forward direction of the first direction, then moves to a second preset position along the forward direction of the second direction in a safety area, and then moves to the second sampling position along the forward direction of the first direction, wherein the safety area is an area where an operator does not prick a hand or an area where the risk of pricking the operator's hand is low.
2. The sample analyzer of claim 1 further comprising a protective structure having a wall extending in the second direction along which the pipette tip moves when the pipette tip moves from the first predetermined position to the second predetermined position.
3. The sample analyzer as claimed in claim 2, wherein the protection structure defines a groove extending along the second direction, and when the sample-sucking needle moves from the first preset position to the second preset position, the sample-sucking needle is located in the groove and moves along the groove; the wall surface is the inner wall of the groove.
4. The sample analyzer of claim 3, wherein the protective structure is provided with an open sample injection control button.
5. The sample analyzer of claim 3, wherein the groove has a cross section in the shape of a major arc segment or a semi-circular arc segment; when the sample sucking needle moves from the first preset position to the second preset position, the sample sucking needle is positioned at the circle center of the cross section of the groove;
or the cross section of the groove is rectangular, and when the sample sucking needle moves from the first preset position to the second preset position, the sample sucking needle is positioned on a symmetrical line of the cross section of the groove, which extends along the first direction.
6. The sample analyzer of claim 3, wherein the width of the opening of the groove toward the first direction is 1cm or less.
7. The sample analyzer of claim 1, wherein the transfer assembly includes a first guide member extending in a horizontal direction, a first moving member slidably coupled to the first guide member, a second guide member extending in a vertical direction, a second moving member slidably coupled to the second guide member, and a third guide member fixedly coupled to the first moving member; the sample sucking needle is fixed on the second moving part.
8. The sample analyzer of claim 1, comprising at least one of:
the sample sucking needle is a sharp-pointed needle;
the first direction is a horizontal direction; and
the second direction is a vertical direction.
9. A method of controlling the movement of a pipette tip of a sample analyzer for controlling the sample analyzer according to any one of claims 1 to 8, comprising the steps of:
the sample sucking needle moves to the first preset position along the positive direction of the first direction;
the sample sucking needle moves from the first preset position to the second preset position along the forward direction of the second direction in a safe area; and
and the sample sucking needle moves to the second sampling position from the second preset position along the forward direction of the first direction.
10. The method for controlling the movement of a pipette tip of a sample analyzer according to claim 9, which comprises at least one of the following conditions:
the sample sucking needle moves from the second sampling position to a third preset position along the reverse direction of the second direction, and the sample sucking needle moves away from the third preset position along the reverse direction of the first direction from the third preset position;
the sample sucking needle moves to a fourth preset position along the forward direction of the first direction, and the sample sucking needle moves to the first sampling position from the fourth preset position along the forward direction of the second direction; and
the sample sucking needle is moved to the fourth preset position along the reverse direction of the second direction from the first sampling position, and the sample sucking needle is moved away from the fourth preset position along the reverse direction of the first direction from the fourth preset position.
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| CN113711050A (en) * | 2019-05-20 | 2021-11-26 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analyzer and liquid suction control method |
| CN117214453B (en) * | 2023-11-07 | 2024-04-05 | 长春迈克赛德医疗科技有限公司 | Sample suction needle system and sample suction method |
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| CN103616527A (en) * | 2013-11-25 | 2014-03-05 | 深圳市锦瑞电子有限公司 | Electrolyte analyzer |
| CN204740254U (en) * | 2015-06-22 | 2015-11-04 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analytical equipment |
| CN105445485A (en) * | 2015-12-26 | 2016-03-30 | 嘉兴凯实生物科技有限公司 | Sample suction device and flow fluorescence detector |
| CN106170704A (en) * | 2014-05-21 | 2016-11-30 | 株式会社日立高新技术 | Detection bodies dispenser and detection bodies dispenser nozzle head |
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| DE102015221024B3 (en) * | 2015-10-28 | 2017-03-30 | Bruker Biospin Gmbh | Needle guide with centering for septum piercing |
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| CN103433256A (en) * | 2013-09-04 | 2013-12-11 | 深圳市锦瑞电子有限公司 | Cleaning device and cleaning method for sampling needle of specific protein analysis meter |
| CN103616527A (en) * | 2013-11-25 | 2014-03-05 | 深圳市锦瑞电子有限公司 | Electrolyte analyzer |
| CN106170704A (en) * | 2014-05-21 | 2016-11-30 | 株式会社日立高新技术 | Detection bodies dispenser and detection bodies dispenser nozzle head |
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Application publication date: 20181218 Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of invention: Sample analyzer and its motion control method for aspirating needle Granted publication date: 20220111 License type: Common License Record date: 20220804 |