CN104374934B - The method of sampling of automatic clinical chemistry analyzer - Google Patents
The method of sampling of automatic clinical chemistry analyzer Download PDFInfo
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- CN104374934B CN104374934B CN201410585159.4A CN201410585159A CN104374934B CN 104374934 B CN104374934 B CN 104374934B CN 201410585159 A CN201410585159 A CN 201410585159A CN 104374934 B CN104374934 B CN 104374934B
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Abstract
The invention discloses and a kind of use automatic clinical chemistry analyzer to carry out the method sampled, the method comprises the steps: a) to drive sampling component to move to sample bits in the horizontal direction；B) driving sampling needle is in movement in vertical direction, and pierces through the container equipped with sample, after drawing sample, is back to sample bits；C) sampling component is driven to move to reaction tank position in the horizontal direction；D) driving sampling needle in movement in vertical direction, sample is joined reaction tank, after the response time set in advance, sampling needle moves to reaction tank position after drawing the reacted mixed liquor of part；E) sampling needle is driven to move to counting chamber position in the horizontal direction；F) driving sampling needle mixed liquor after movement in vertical direction, the partial reaction draw sampling needle to be injected in counting chamber, sampling needle is retracted into counting chamber position；G) sampling needle is driven to move to initial position in the horizontal direction.This method of sampling step is simple, and sampling efficiency is high, low cost.
Description
Technical field
The present invention relates to a kind of method of sampling, particularly relate to the method for sampling of a kind of automatic clinical chemistry analyzer, the method may be used for medical treatment detection industry, it is possible to realizes open sampling, close the functions such as sampling and sample delivery.
Background technology
Automatic clinical chemistry analyzer is a kind of instrument that the comparison of application is wide in the detection measuring the physiochemistry of human body fluid, physical property.In automatic clinical chemistry analyzer, sampler is unusual part and parcel.Sampler needs liquid sample to transfer in Specimen bottle reagent bottle, after fully reacting, then detects in mixed liquor is transferred to enumerator.Chinese utility model patent the 200520094284.1st discloses sampling and the agitating device of a kind of automatic clinical chemistry analyzer.This device includes that suspended wall mechanism and drive mechanism, suspended wall mechanism are connected in drive mechanism.Wherein, suspended wall mechanism includes sampling mixing arm, stirring paddle and sampling probe, and one end of sampling mixing arm is connected with drive mechanism, and the other end is free end.Motor is fixed on sampling mixing arm by electric machine support.Below the free end of sampling mixing arm, it is connected with clutch shaft bearing seat, is provided with the first rolling bearing in it, the first rolling bearing is provided with power transmission shaft.On motor and one end of power transmission shaft is equipped with belt wheel, it is connected by transmission band between two belt wheels.The other end of power transmission shaft is affixed with stirring paddle.One end of sampling probe is fixed in the top of the free end of sampling mixing arm by sampling probe support, and the other end is inserted in power transmission shaft and stirring paddle.
Above-mentioned automatic clinical chemistry analyzer includes a suspended wall rotated, and is therefore only capable of rotating in the angle limited around its column, and its range of activity is restricted, and is not suitable for some occasion needing to do two-dimensional freedom motion in certain plane.
Summary of the invention
In order to overcome above-mentioned shortcoming of the prior art, an object of the present invention is: provide a kind of sampling apparatus with two-dimensional freedom motor function.Described sampling apparatus includes: frame, horizontal motion system, movement in vertical direction system, sampling component and power transmission guide rail, horizontal motion system includes the first motor, movement in vertical direction system includes the second motor, first motor and the second motor are respectively and fixedly installed in frame, sampling component includes sampling needle briquetting and sampling needle, power transmission guide rail horizontal positioned and fixing with movement in vertical direction system and sampling needle briquetting be respectively connected, horizontal motion system drive sampling needle moves in the horizontal direction, movement in vertical direction system drive sampling needle is in movement in vertical direction.
To improving further of technique scheme it is: described horizontal motion system also includes the first Timing Belt and horizontal guide rail；Described movement in vertical direction system also includes that the second Timing Belt, first axis of guide and guide rail briquetting, guide rail briquetting and the second Timing Belt are fixing and connects；Described sampling component also includes sampling component support and second axis of guide.
It is: the connection fixing with the first Timing Belt of sampling component support that the slide block of sampling component support and horizontal guide rail is fixed to improving further of technique scheme；Under the driving of the first motor, sampling component carries out horizontal motion under the guide effect of horizontal guide rail；The slide block of power transmission guide rail and the fixing connection of sampling needle briquetting, under the driving of the second motor, sampling needle briquetting makees movement in vertical direction along with power transmission guide rail.
To improving further of technique scheme it is: guide rail briquetting and the fixing connection of power transmission guide rail.
To improving further of technique scheme it is: sampling needle briquetting includes that lead, guide rail briquetting are provided with the hole matched with lead.
To improving further of technique scheme it is: lead is partial cone.
To improving further of technique scheme it is: also include that optical coupled switch, described optocoupler open the light and be arranged in frame.
To improving further of technique scheme it is: on sampling component support and guide rail briquetting, be separately installed with optical coupled switch sensing chip.
To improving further of technique scheme it is: described power transmission guide rail and horizontal guide rail are parallel to each other.
To improving further of technique scheme it is: sampling component moves to sample bits, reaction tank position and counting chamber position the most successively.
The two of the purpose of the present invention are: provide the method for sampling of a kind of automatic clinical chemistry analyzer.Described automatic clinical chemistry analyzer includes frame, horizontal motion system, movement in vertical direction system, sampling component and power transmission guide rail.Wherein, horizontal motion system includes that the first motor, movement in vertical direction system include the second motor.First motor and the second motor are separately mounted in frame.Sampling component includes sampling needle briquetting and sampling needle.Power transmission guide rail horizontal positioned and fixing with movement in vertical direction system and sampling needle briquetting be respectively connected.Described method comprises the steps:
A) start the first motor, drive sampling component to move to sample bits in the horizontal direction, close the first motor；
B) starting the second motor, driving sampling needle is in movement in vertical direction, and pierces through the container equipped with sample, after drawing sample, is back to sample bits, closes the second motor；
C) start the first motor, drive sampling component to move to reaction tank position in the horizontal direction, close the first motor；
D) starting the second motor, drive sampling needle in movement in vertical direction, sample is joined reaction tank, after the response time set in advance, sampling needle moves to reaction tank position after drawing the reacted mixed liquor of part, closes the second motor；
E) start the first motor, drive sampling needle to move to counting chamber position in the horizontal direction, close the first motor；F) starting the second motor, drive sampling needle mixed liquor after movement in vertical direction, the partial reaction draw sampling needle to be injected in counting chamber, sampling needle is retracted into counting chamber position, closes the second motor；
G) start the first motor, drive sampling needle to move to initial position in the horizontal direction, close the first motor.
To improving further of technique scheme it is: described horizontal motion system also includes the first Timing Belt and horizontal guide rail；Described movement in vertical direction system also includes that the second Timing Belt, first axis of guide and guide rail briquetting, guide rail briquetting and the second Timing Belt are fixing and connects；Described sampling component also includes sampling component support and second axis of guide.
To improving further of technique scheme it is: the first synchronous pulley is installed on the first stepping motor rotating shaft, first Timing Belt makees horizontal motion under the driving of the first synchronous pulley, sampling component support and the fixing connection of the first Timing Belt, sampling component support is fixing with the slide block of power transmission guide rail to be connected；The slide block of power transmission guide rail is fixing with sampling needle briquetting to be connected, and power transmission guide rail and horizontal guide rail are placed in parallel；When first Timing Belt moves in the horizontal direction, sampling component carries out horizontal reciprocating movement under horizontal guide rail and power transmission guide rail guide jointly.
To improving further of technique scheme it is: guide rail briquetting and sampling needle briquetting make vertical sliding motion respectively on first axis of guide and second axis of guide；Guide rail briquetting and the fixing connection of Timing Belt；The slide block of power transmission guide rail and the fixing connection of sampling needle briquetting；When the second Timing Belt makees the motion of vertical direction under the driving of the second motor, guide rail briquetting drives sampling needle briquetting to make vertical back and forth movement under the guiding of first and second axis of guides by power transmission guide rail indirectly；Sampling needle and the fixing connection of sampling needle briquetting, sampling needle is followed power transmission guide rail under the second Timing Belt drives and is done vertical displacement movement, completes to inhale sample and sample presentation action.
It is: when the second motor cuts out, during the first stepping electric motor starting that sampling component moves to specify position in the horizontal direction to improving further of technique scheme；When the first motor cuts out the second stepping electric motor starting, sampling needle is followed power transmission under the second Timing Belt drives and is led and do vertical displacement movement.
To improving further of technique scheme it is: described appointment position includes sample bits, reaction tank position, counting chamber position.
To improving further of technique scheme it is: sampling apparatus also includes that optical coupled switch, described optocoupler open the light in the frame being arranged on sampling apparatus；It is separately installed with optical coupled switch sensing chip on sampling component support and guide rail briquetting, switching signal will be sent to control system when sensing chip shelters from optocoupler.
To improving further of technique scheme it is: sampling needle briquetting includes lead, guide rail briquetting has the bellmouth coordinated with lead in relevant position, when sampling component contacts with guide rail briquetting, lead keeps sampling component and briquetting ground to be in close contact in screwing in bellmouth.
To improving further of technique scheme it is: described lead is cone.
To improving further of technique scheme it is: sampling component horizontal motion is to when contacting with guide rail briquetting, sampling needle briquetting is guided by the bellmouth of lead and guide rail briquetting and combines, jointly lower driving sampling needle is pulled to perform puncture of test tube and draw sample action at the second Timing Belt, after suction sample completes, sampling needle briquetting disengages guide rail briquetting, then drives sampling needle to carry sample to horizontal direction.
The three of the purpose of the present invention are: provide a kind of sampling apparatus, including sampling component and movement in vertical direction system.Described sampling component includes that sampling needle briquetting and sampling needle, described movement in vertical direction system include the second motor and guide rail briquetting, and the second motor is separately positioned with sampling component；Sampling needle briquetting includes lead, and guide rail briquetting is provided with the hole coordinated with lead in relevant position, and when sampling component contacts with guide rail briquetting, lead is received in hand-hole, keeps sampling component and briquetting ground to be in close contact.
To improving further of technique scheme it is: described movement in vertical direction system also includes the second Timing Belt, first axis of guide being parallel to the second Timing Belt and can fix connection at the guide rail briquetting of the first axis of guide sliding, guide rail briquetting and the second Timing Belt.
To improving further of technique scheme it is: when sampling component contacts with guide rail briquetting, sampling needle briquetting is guided by the bellmouth of lead and guide rail briquetting and combines, jointly under the second Timing Belt drives, sampling needle is driven to perform puncture of test tube and draw sample action, after suction sample completes, sampling needle briquetting disengages guide rail briquetting, then drives sampling needle to carry sample to horizontal direction.
It is: also include that power transmission guide rail, one end of described power transmission guide rail are rigidly connected with guide rail briquetting that the other end of power transmission guide rail is fixing with sampling needle briquetting to be connected to improving further of technique scheme.
To improving further of technique scheme it is: sampling needle stops in sample bits, reaction tank position and counting chamber position respectively, and wherein, sample bits will be closer to the second motor than reaction tank position and counting chamber position.
The four of the purpose of the present invention are: provide a kind of automatic clinical chemistry analyzer.Described automatic clinical chemistry analyzer includes the sampling apparatus with two-dimensional freedom motor function.This sampling apparatus includes: frame, horizontal motion system, movement in vertical direction system, sampling component and power transmission guide rail, horizontal motion system includes the first motor, movement in vertical direction system includes the second motor, first motor and the second motor are respectively and fixedly installed in frame, sampling component includes sampling needle briquetting and sampling needle, power transmission guide rail horizontal positioned and fixing with movement in vertical direction system and sampling needle briquetting be respectively connected, horizontal motion system drive sampling needle moves in the horizontal direction, movement in vertical direction system drive sampling needle is in movement in vertical direction.
To improving further of technique scheme it is: described horizontal motion system also includes the first Timing Belt and horizontal guide rail；Described movement in vertical direction system also includes that the second Timing Belt, first axis of guide and guide rail briquetting, guide rail briquetting and the second Timing Belt are fixing and connects；Described sampling component also includes sampling component support and second axis of guide.
It is: the connection fixing with the first Timing Belt of sampling component support that the slide block of sampling component support and horizontal guide rail is fixed to improving further of technique scheme；Under the driving of the first motor, sampling component carries out horizontal motion under the guide effect of horizontal guide rail；The slide block of power transmission guide rail and the fixing connection of sampling needle briquetting, under the driving of the second motor, sampling needle briquetting makees movement in vertical direction along with power transmission guide rail.
To improving further of technique scheme it is: guide rail briquetting and the fixing connection of power transmission guide rail.
To improving further of technique scheme it is: sampling needle briquetting includes that lead, guide rail briquetting are provided with the hole matched with lead.
To improving further of technique scheme it is: lead is partial cone.
To improving further of technique scheme it is: also include that optical coupled switch, described optocoupler open the light and be arranged in frame.
To improving further of technique scheme it is: on sampling component support and guide rail briquetting, be separately installed with optical coupled switch sensing chip.
To improving further of technique scheme it is: described power transmission guide rail and horizontal guide rail are parallel to each other.
To improving further of technique scheme it is: sampling component moves to sample bits, reaction tank position and counting chamber position the most successively.
The invention has the beneficial effects as follows: power transmission guide rail one end is fixed on guide rail briquetting, guide rail briquetting has the Baltimore groove matched with power transmission guide rail, and back and top have screw to ensure to be rigidly connected simultaneously.Second slide block of power transmission guide rail is fixed by screws in sampling needle briquetting, and when Timing Belt drives guide rail briquetting and power transmission guide rail movement in vertical direction, sampling needle moves up and down the most therewith.Horizontally and vertically can arrange optocoupler to position, thus carry out sampling and transmitting sample in specific position.Sampling needle briquetting is threaded connection lead, guide rail briquetting is also equipped with the bellmouth coordinated with lead in corresponding positions, moment required during in order to reduce puncture of test tube, sampling component horizontal motion contacts to guide rail briquetting, and sampling needle is followed power transmission guide rail and jointly completed puncture action.This motion motor is each attached in instrument frame, and motion is light and handy, spaces compact, conveying sample to ad-hoc location function, requires low to the loading moment of motor, and mechanicalness noise is little.The most compatible open sampling and puncture sampling, be suitable for the medical apparatus and instruments such as blood analyser and Urine Analyzer.
Accompanying drawing explanation
Fig. 1 is the plane graph of a kind of two-dimensional freedom motion of the present invention.
Fig. 2 is the axonometric chart of a kind of two-dimensional freedom motion of the present invention.
Fig. 3 is the another kind of two-dimensional freedom motion open sampling location plane graph of the present invention.
Fig. 4 is the another kind of two-dimensional freedom motion open sampling location axonometric chart of the present invention.
Fig. 5 is the plane graph that the another kind of two-dimensional freedom motion horizontal motion of the present invention arrives certain ad-hoc location.
Fig. 6 is the plane graph that the another kind of two-dimensional freedom motion movement in vertical direction of the present invention arrives another certain ad-hoc location.
Fig. 7 is the plane graph of the another kind of two-dimensional freedom motion horizontal motion arrival puncture position of the present invention.
Fig. 8 is the another kind of two-dimensional freedom motion guider generalized section of the present invention.
Fig. 9 is the plane graph that the another kind of two-dimensional freedom motion of the present invention carries out puncture of test tube.
Figure 10 is the structural perspective of the another kind of two-dimensional freedom motion guide rail briquetting 104 of the present invention.
Detailed description of the invention
Embodiment one
Referring to Fig. 1 and Fig. 2, this is a kind of specific embodiment of sampling apparatus of the present invention.This sampling apparatus is completed to guide by two horizontally-guided axles 2 and 5.First motor 4 drives Timing Belt 3 to drive sampling component to complete horizontal motion (sampling component is by sampling component support 10 and the fixing connection of Timing Belt 3).The second motor 1 being arranged on sampling component support 10 drives Timing Belt 6 to drive sampling needle 7 to complete movement in vertical direction under the guide effect of two vertically-guided axles 8 and 9.Sampling needle 7 moves at two-dimensional freedom both horizontally and vertically and contributes to realizing the functions such as puncture of test tube, sample absorption and sample transport in blood cell analysis device.
Embodiment two
Shown in Fig. 3 to Figure 10 is the present invention another kind sampling apparatus with two-dimensional freedom motion.Described two-dimensional freedom refers to that this motion or parts therein can be fixed along certain or move respectively in the direction at place, two limits of on-fixed angle.Described fixed angle can be 150 degree, 120 degree, 90 degree, 60 degree, 30 degree or other any suitable angles.The movement locus of two-dimensional freedom can be straight line, smooth curve, smooth parabola, take out stitches or a combination thereof.In the preferred version of the present invention, described two-dimensional freedom refers to orthogonal two rectilinear directions.Scheme more preferably is: the motion of described two-dimensional freedom includes the motion parts of horizontal direction and the motion parts of vertical direction.Produce two-dimensional freedom motion horizontally and vertically using the present invention below and illustrate the specific embodiments of the present invention as one of the specific embodiment of the present invention.Realize other angle and directions two-dimensional freedom motion specific embodiments can by parity of reasoning obtains.
Referring to Fig. 3, Fig. 4 and Fig. 5, horizontal motion device includes that the first motor 116(main frame is blocked and only exposes rotating shaft), first Timing Belt the 109, first synchronous pulley 113, horizontal guide rail 108 and sampling component 99.Described sampling component 99 includes sampling component support 112, second axis of guide 115 being fixed to support 112, be enclosed within second axis of guide 115 and can be along the sampling needle briquetting 114 of the second axis of guide 115 parallel sliding and the sampling needle 111 etc. being fixed to sampling needle briquetting 114.First motor 116 is fixed in sampling apparatus frame 100 by screw, bolt or rivet etc..The rotating shaft of the first motor 116 and the first synchronous pulley 113 make synchronous axial system.First Timing Belt 109 is installed on first synchronous pulley 113.Preferably, the outline of the first synchronous pulley 113 is gear, and the first Timing Belt 109 is the gear band matched with this gear.First Timing Belt 109 is driven the motion making horizontal direction by the first synchronous pulley 113.Sampling component support 112 is fixed to the first Timing Belt 109 by screw and clamping plate (not shown), and keeps being synchronized with the movement with the first Timing Belt 109.Sampling component support 112 is fixed with at least one first slide block 118.Sampling apparatus frame 100 is fixed with at least one horizontal guide rail 108.Described first slide block 118 is slidably matched with described horizontal guide rail 108.During the first motor 116 drives the first Timing Belt 109 motion, first Timing Belt 109 drives sampling component support 112(together with whole sampling component 99) make moving of horizontal direction along horizontal guide rail 108, it is achieved thereby that the motion that this device is in the horizontal direction.
As shown in Figure 4, the second slide block 119 being slidably connected with power transmission guide rail 101 is connected by screw is fixing with sampling needle briquetting 114.Power transmission guide rail 101 should be parallel to each other with horizontal guide rail 108, therefore, when the first Timing Belt 109 drives sampling component support 112(together with whole sampling component 99) make when moving of horizontal direction along horizontal guide rail 108, sampling needle briquetting 114 keeps not being subjected to displacement in vertical direction.
As shown in Figures 3 and 4, movement in vertical direction device includes second motor the 103, second Timing Belt the 105, second synchronous pulley 106, guide rail briquetting 104 and power transmission guide rail 101.Second Timing Belt 105 is tightened by power output shaft and second synchronous pulley 106 of the second motor 103, and follows the second motor and be synchronized with the movement.Preferably, the second synchronous pulley 106 is gear, and the second Timing Belt 105 is the gear band matched with synchronous pulley.Power transmission guide rail 101 is fixed to the second Timing Belt 105 by guide rail briquetting 104, and is synchronized with the movement together with the second Timing Belt 105.Sampling needle briquetting 114 is slidably matched with power transmission guide rail 101 by the second slide block 119 thereon, thus level can slide on power transmission guide rail 101.Power transmission guide rail 101 and horizontal guide rail 108 and the first mutual horizontal parallel of Timing Belt 109.Being fixed with first axis of guide 107 in frame 100, guide rail briquetting 104 is mounted to described first axis of guide 107, and can on first axis of guide 107 vertical sliding motion.Being fixed with second axis of guide 115 on sampling component support 112, sampling needle briquetting 114 is mounted to described second axis of guide 115, and can on second axis of guide 115 vertical sliding motion.Described first axis of guide 107, second axis of guide 115 is mutually perpendicular to parallel with the second Timing Belt 105.When the second motor 103 starts, the second Timing Belt 105 is followed the second motor 103 and is synchronized with the movement.Owing to the second Timing Belt 105 is fixed be connected with guide rail briquetting 104 and power transmission guide rail 101, therefore, power transmission guide rail 101 is driven by the second motor 103 and moves up and down in vertical direction.
Referring to Fig. 3 and Fig. 4, due to the needs guided, first axis of guide 107 and second axis of guide 115 and the second Timing Belt 105 need vertical parallel placement.Sampling needle briquetting 114 and guide rail briquetting 104 are internal can vertical sliding motion on second axis of guide 115 and first axis of guide 107 respectively equipped with linear bearing (not shown).The relative position of guide rail briquetting 104 with the second Timing Belt 105 is fixed with clamping plate (not shown) by guide rail briquetting 104 by screw.Guide rail briquetting 104 is provided with Baltimore groove 121(and sees Figure 10), described power transmission guide rail 101 is housed in this Baltimore groove 121, and is made by screw that guide rail briquetting 104 and power transmission guide rail 101 is fixing to be connected.As it was previously stated, be slidingly attached to the second slide block 119 and the fixing connection of sampling needle briquetting 114 of power transmission guide rail 101, so, power transmission guide rail 101 is just simultaneously connected with guide rail briquetting 104 and sampling needle briquetting 114.Sampling needle briquetting 114 and guide rail briquetting 104 have identical or similar structure.When the second Timing Belt 105 is fixedly mounted in frame at the second motor 103() driving under when making movement in vertical direction, guide rail briquetting 104, under the guide effect of first axis of guide 107 and second axis of guide 115, indirectly drives sampling needle briquetting 114 to do the back and forth movement of vertical direction by power transmission guide rail 101.It is connected owing to sampling needle 111 is fixing with sampling needle briquetting 114, so, sampling needle 111 just can follow power transmission guide rail 101 under the drive of the second Timing Belt 105, do the elevating movement of vertical direction, thus complete draw liquid sample and transmit the operation of liquid sample.
In sum, when the second motor 103 do not work, the first motor 116 work time, sampling component 99 just can move in the horizontal direction specify position, such as sample bits, reaction tank position, counting chamber position etc..When the first motor 116 do not work, the second motor 103 work time, sampling needle 111 just can be followed power transmission guide rail 101 under the drive of the second Timing Belt 105 and be done the elevating movement of vertical direction.Horizontal motion and being accurately positioned of movement in vertical direction rely on the several sensing optocouplers 102 being arranged in frame 100 to realize location.The operation principle of optocoupler is: will send switching signal to control system when sensing chip shelters from optocoupler.Therefore, sampling component support 112 and guide rail briquetting 104 are all respectively provided with a sensing steel disc (not shown).Referring to Figure 10, guide rail briquetting 104 is provided with the groove 121 matched with power transmission guide rail 101, has screw 120 to hold out against guide rail above groove, and front has two screws and guide rail to ensure to connect reliably.The surface of power transmission guide rail 101 and horizontal guide rail 108 keeping parallelism.Power transmission guide rail 101 has two effect: a, guides sampling component carrying out horizontal；B, in vertical direction transmission moment carry out puncturing test tube to sampling component.
When drawing liquid sample, sampling needle sometimes needs to pierce through the test tube cap equipped with liquid sample, accordingly, it would be desirable to sampling needle is applied certain thrust.Refer to shown in Fig. 7 to Figure 10, in order to reach preferably to pierce through effect, it should make sampling component close to guide rail briquetting 104, thus reduce the moment that power transmission guide rail 101 produces as far as possible.In order to reduce the pressure that power transmission guide rail 101 is born when piercing through test tube cap further, the present invention goes back one lead 110 of additional designs.Specifically, a lead 110 is highlighted at sampling needle briquetting 104 in the face of the one side of guide rail briquetting 104.So lead 110 can be with sampling needle briquetting 104 Integral design, it is also possible to be connected by screwed hole or other modes are fixing with sampling needle briquetting 104.This lead 110 can be designed to cylinder or the cone of tip of pruning, it is also possible to be cross section be trapezoidal any body.Guide rail briquetting 104 also has the hole 122 of bellmouth or other shapes matched with lead 110 profile in relevant position.When sampling component contacts with guide rail briquetting 104, lead 110 inserts the hole 122 on briquetting 104 and keeps certain closely cooperating.Moment required during in order to reduce puncture of test tube, sampling component horizontal motion is to when contacting with guide rail briquetting 104, sampling needle briquetting 114 is mainly guided by lead 110 and guide rail briquetting 104 and combines, under the pulling of the second Timing Belt 105, guide rail briquetting 104 drives sampling needle briquetting 114 to move downward by lead 110.Sampling needle briquetting 114 drives sampling needle 111 to move down further, thus performs puncture test tube cap and draw the action of sample.After suction sample completes, sampling needle briquetting 114 can disengage guide rail briquetting 104 smoothly, then drives sampling needle 111 to horizontal direction conveying sample to reaction tank position.
The invention still further relates to a kind of method utilizing automatic clinical chemistry analyzer to carry out sampling.Described automatic clinical chemistry analyzer includes sampling apparatus, and this sampling apparatus includes frame, horizontal motion system, movement in vertical direction system, sampling component and power transmission guide rail.Wherein, horizontal motion system includes that the first motor, movement in vertical direction system include the second motor.First motor and the second motor are separately mounted in frame.Sampling component includes sampling needle briquetting and sampling needle.Power transmission guide rail horizontal positioned and fixing with movement in vertical direction system and sampling needle briquetting be respectively connected.Described method comprises the steps:
A) start the first motor, drive sampling component to move to sample bits in the horizontal direction, close the first motor；
B) starting the second motor, driving sampling needle is in movement in vertical direction, and pierces through the container equipped with sample, after drawing sample, is back to sample bits, closes the second motor；
C) start the first motor, drive sampling component to move to reaction tank position in the horizontal direction, close the first motor；
D) starting the second motor, drive sampling needle in movement in vertical direction, sample is joined reaction tank, after the response time set in advance, sampling needle moves to reaction tank position after drawing the reacted mixed liquor of part, closes the second motor；
E) start the first motor, drive sampling needle to move to counting chamber position in the horizontal direction, close the first motor；F) starting the second motor, drive sampling needle mixed liquor after movement in vertical direction, the partial reaction draw sampling needle to be injected in counting chamber, sampling needle is retracted into counting chamber position, closes the second motor；
G) start the first motor, drive sampling needle to move to initial position in the horizontal direction, close the first motor.
To improving further of technique scheme it is: described horizontal motion system also includes the first Timing Belt and horizontal guide rail；Described movement in vertical direction system also includes that the second Timing Belt, first axis of guide and guide rail briquetting, guide rail briquetting and the second Timing Belt are fixing and connects；Described sampling component also includes sampling component support and second axis of guide.
To improving further of technique scheme it is: the first synchronous pulley is installed on the first stepping motor rotating shaft, first Timing Belt makees horizontal motion under the driving of the first synchronous pulley, sampling component support and the fixing connection of the first Timing Belt, sampling component support is fixing with the slide block of power transmission guide rail to be connected；The slide block of power transmission guide rail is fixing with sampling needle briquetting to be connected, and power transmission guide rail and horizontal guide rail are placed in parallel；When first Timing Belt moves in the horizontal direction, sampling component carries out horizontal reciprocating movement under horizontal guide rail and power transmission guide rail guide jointly.
To improving further of technique scheme it is: guide rail briquetting and sampling needle briquetting make vertical sliding motion respectively on first axis of guide and second axis of guide；Guide rail briquetting and the fixing connection of Timing Belt；The slide block of power transmission guide rail and the fixing connection of sampling needle briquetting；When the second Timing Belt makees the motion of vertical direction under the driving of the second motor, guide rail briquetting drives sampling needle briquetting to make vertical back and forth movement under the guiding of first and second axis of guides by power transmission guide rail indirectly；Sampling needle and the fixing connection of sampling needle briquetting, sampling needle is followed power transmission guide rail under the second Timing Belt drives and is done vertical displacement movement, completes to inhale sample and sample presentation action.
It is: when the second motor cuts out, during the first stepping electric motor starting that sampling component moves to specify position in the horizontal direction to improving further of technique scheme；When the first motor cuts out the second stepping electric motor starting, sampling needle is followed power transmission under the second Timing Belt drives and is led and do vertical displacement movement.
To improving further of technique scheme it is: described appointment position includes sample bits, reaction tank position, counting chamber position.
To improving further of technique scheme it is: sampling apparatus also includes that optical coupled switch, described optocoupler open the light in the frame being arranged on sampling apparatus；It is separately installed with optical coupled switch sensing chip on sampling component support and guide rail briquetting, switching signal will be sent to control system when sensing chip shelters from optocoupler.
To improving further of technique scheme it is: sampling needle briquetting includes lead, guide rail briquetting has the bellmouth coordinated with lead in relevant position, when sampling component contacts with guide rail briquetting, lead keeps sampling component and briquetting ground to be in close contact in screwing in bellmouth.
To improving further of technique scheme it is: described lead is cone.
To improving further of technique scheme it is: sampling component horizontal motion is to when contacting with guide rail briquetting, sampling needle briquetting is guided by the bellmouth of lead and guide rail briquetting and combines, jointly lower driving sampling needle is pulled to perform puncture of test tube and draw sample action at the second Timing Belt, after suction sample completes, sampling needle briquetting disengages guide rail briquetting, then drives sampling needle to carry sample to horizontal direction.
Sampling apparatus and the method for sampling of the present invention are with a wide range of applications, such as, can be used for the fields such as blood cell analysis machine.
Above content is to combine specific embodiment further description made for the present invention, it is impossible to assert the present invention be embodied as be confined to these explanations.For general technical staff of the technical field of the invention; without departing from the inventive concept of the premise; (in such as this example, power transmission guide rail uses straight ball-guide can also to make some simple deduction or replace; can be changed into roller type linear slide rail etc.), all should be considered as belonging to protection scope of the present invention.
Claims (10)
1. one kind utilizes the method that automatic clinical chemistry analyzer carries out sampling, described automatic clinical chemistry analyzer includes sampling apparatus, it is characterized in that: this sampling apparatus includes frame, horizontal motion system, movement in vertical direction system, sampling component and power transmission guide rail, wherein, horizontal motion system includes the first motor, movement in vertical direction system includes the second motor and by the second stepper motor driven second Timing Belt, power transmission guide rail is fixed to the second Timing Belt by guide rail briquetting, first motor and the second motor are separately mounted in frame, sampling component includes sampling needle briquetting and sampling needle, power transmission guide rail horizontal positioned and and sampling needle briquetting be slidably connected；Described method comprises the steps:
A) start the first motor, drive sampling component to move to sample bits in the horizontal direction, close the first motor；
B) starting the second motor, driving sampling needle is in movement in vertical direction, and pierces through the container equipped with sample, after drawing sample, is back to sample bits, closes the second motor；
C) start the first motor, drive sampling component to move to reaction tank position in the horizontal direction, close the first motor；
D) starting the second motor, drive sampling needle in movement in vertical direction, sample is joined reaction tank, after the response time set in advance, sampling needle moves to reaction tank position after drawing the reacted mixed liquor of part, closes the second motor；
E) start the first motor, drive sampling needle to move to counting chamber position in the horizontal direction, close the first motor；F) starting the second motor, drive sampling needle mixed liquor after movement in vertical direction, the partial reaction draw sampling needle to be injected in counting chamber, sampling needle is retracted into counting chamber position, closes the second motor；
G) start the first motor, drive sampling needle to move to initial position in the horizontal direction, close the first motor.
Method the most according to claim 1, it is characterised in that described horizontal motion system also includes the first Timing Belt and horizontal guide rail；Described movement in vertical direction system also includes that the second Timing Belt, first axis of guide and guide rail briquetting, guide rail briquetting and the second Timing Belt are fixing and connects；Described sampling component also includes sampling component support and second axis of guide.
Method the most according to claim 2, it is characterized in that, first synchronous pulley is installed on the first stepping motor rotating shaft, first Timing Belt makees horizontal motion under the driving of the first synchronous pulley, sampling component support and the fixing connection of the first Timing Belt, sampling component support is fixing with the slide block of horizontal guide rail to be connected；The slide block of power transmission guide rail is fixing with sampling needle briquetting to be connected, and power transmission guide rail and horizontal guide rail are placed in parallel；When first Timing Belt moves in the horizontal direction, sampling component carries out horizontal reciprocating movement under horizontal guide rail and power transmission guide rail guide jointly.
Method the most according to claim 2, it is characterised in that guide rail briquetting and sampling needle briquetting make vertical sliding motion respectively on first axis of guide and second axis of guide；Guide rail briquetting and the fixing connection of the second Timing Belt；The slide block of power transmission guide rail and the fixing connection of sampling needle briquetting；When the second Timing Belt makees the motion of vertical direction under the driving of the second motor, guide rail briquetting drives sampling needle briquetting to make vertical back and forth movement under the guiding of first and second axis of guides by power transmission guide rail indirectly；Sampling needle and the fixing connection of sampling needle briquetting, sampling needle is followed power transmission guide rail under the second Timing Belt drives and is done vertical displacement movement, completes to inhale sample and sample presentation action.
Method the most according to claim 2, it is characterised in that when the second motor cuts out, during the first stepping electric motor starting, sampling component moves to specify position in the horizontal direction；When the first motor cuts out the second stepping electric motor starting, sampling needle is followed power transmission guide rail under the second Timing Belt drives and is done vertical displacement movement.
Method the most according to claim 5, it is characterised in that described appointment position includes sample bits, reaction tank position, counting chamber position.
Method the most according to claim 1, it is characterised in that sampling apparatus also includes sampling component support, guide rail briquetting and optical coupled switch, described optocoupler opens the light in the frame being arranged on sampling apparatus；It is separately installed with optical coupled switch sensing chip on sampling component support and guide rail briquetting, switching signal will be sent to control system when sensing chip shelters from optocoupler.
Method the most according to claim 1, it is characterized in that, sampling apparatus includes lead and guide rail briquetting, guide rail briquetting has the bellmouth coordinated with lead in relevant position, when sampling component contacts with guide rail briquetting, lead keeps sampling component and guide rail briquetting ground to be in close contact in screwing in bellmouth.
Method the most according to claim 8, it is characterised in that described lead is cone.
Method the most according to claim 8, it is characterized in that, sampling component horizontal motion is to when contacting with guide rail briquetting, sampling needle briquetting is guided by the bellmouth of lead and guide rail briquetting and combines, jointly lower driving sampling needle is pulled to perform puncture of test tube and draw sample action at the second Timing Belt, after suction sample completes, sampling needle briquetting disengages guide rail briquetting, then drives sampling needle to carry sample to horizontal direction.
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| CN201410585159.4A CN104374934B (en) | 2014-10-28 | 2014-10-28 | The method of sampling of automatic clinical chemistry analyzer |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN204269661U (en) * | 2014-10-28 | 2015-04-15 | 利多(香港)有限公司 | The sampling apparatus of full-automatic Hematometer |
| CN108318312A (en) * | 2017-01-16 | 2018-07-24 | 深圳市美侨医疗科技有限公司 | Urinary formed element staining analysis instrument |
| CN113711050A (en) * | 2019-05-20 | 2021-11-26 | 深圳迈瑞生物医疗电子股份有限公司 | Sample analyzer and liquid suction control method |
| CN111893037A (en) * | 2019-12-12 | 2020-11-06 | 山东鑫科生物科技股份有限公司 | Bacteria counting device with multi-probe movement mechanism |
| CN111893036A (en) * | 2019-12-12 | 2020-11-06 | 山东鑫科生物科技股份有限公司 | Bacterium counting assembly with bubble mixing mechanism |
| CN111893032A (en) * | 2019-12-12 | 2020-11-06 | 山东鑫科生物科技股份有限公司 | Bacteria counting device with air cleaning mechanism |
| CN114414308A (en) * | 2022-03-28 | 2022-04-29 | 深圳市帝迈生物技术有限公司 | Sampling device and sampling method of sample analyzer |
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