CN103429574B - 作为蛋白质去乙酰化酶抑制剂的嘧啶羟基酰胺化合物和其使用方法 - Google Patents

作为蛋白质去乙酰化酶抑制剂的嘧啶羟基酰胺化合物和其使用方法 Download PDF

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Publication number
CN103429574B
CN103429574B CN201180055168.7A CN201180055168A CN103429574B CN 103429574 B CN103429574 B CN 103429574B CN 201180055168 A CN201180055168 A CN 201180055168A CN 103429574 B CN103429574 B CN 103429574B
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disease
compound
cancer
optionally substituted
pharmaceutically acceptable
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CN103429574A (zh
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约翰·H·范迪泽
拉尔夫·马齐切克
言彬·丁
郁楠
曹云
刘勇
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Acetylon Pharmaceuticals Inc
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CN201180055168.7A 2010-11-16 2011-11-15 作为蛋白质去乙酰化酶抑制剂的嘧啶羟基酰胺化合物和其使用方法 Expired - Fee Related CN103429574B (zh)

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CN201610911460.9A CN107011270A (zh) 2010-11-16 2011-11-15 作为蛋白质去乙酰化酶抑制剂的嘧啶羟基酰胺化合物和其使用方法

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US41415810P 2010-11-16 2010-11-16
US61/414,158 2010-11-16
US201161503286P 2011-06-30 2011-06-30
US61/503,286 2011-06-30
PCT/US2011/060791 WO2012068109A2 (en) 2010-11-16 2011-11-15 Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof

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CN103429574B true CN103429574B (zh) 2016-11-16

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CN201610911460.9A Pending CN107011270A (zh) 2010-11-16 2011-11-15 作为蛋白质去乙酰化酶抑制剂的嘧啶羟基酰胺化合物和其使用方法

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US (3) US8614223B2 (enExample)
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LT2526093T (lt) 2010-01-22 2016-10-10 Acetylon Pharmaceuticals, Inc. Grįžtamieji amido junginiai kaip baltymo deacetilazės inhibitoriai ir jų panaudojimo būdai
JP6041808B2 (ja) * 2010-11-16 2016-12-14 アセチロン ファーマシューティカルズ インコーポレイテッドAcetylon Pharmaceuticals,Inc. 蛋白質脱アセチル化酵素抑制剤としてのピリミジン水酸基アミド化合物およびその利用方法
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