CN103394092B - 由结冷胶和氯化钙凝胶的羟丙甲纤维素肠溶空心胶囊 - Google Patents
由结冷胶和氯化钙凝胶的羟丙甲纤维素肠溶空心胶囊 Download PDFInfo
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- CN103394092B CN103394092B CN201310346229.6A CN201310346229A CN103394092B CN 103394092 B CN103394092 B CN 103394092B CN 201310346229 A CN201310346229 A CN 201310346229A CN 103394092 B CN103394092 B CN 103394092B
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- hypromellose
- capsule
- solution
- calcium chloride
- gellan gum
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- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 title claims abstract description 56
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 title claims abstract description 56
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 title claims abstract description 56
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 title claims abstract description 18
- 239000001110 calcium chloride Substances 0.000 title claims abstract description 18
- 229910001628 calcium chloride Inorganic materials 0.000 title claims abstract description 18
- 229920002148 Gellan gum Polymers 0.000 title claims abstract description 17
- 239000000216 gellan gum Substances 0.000 title claims abstract description 17
- 235000010492 gellan gum Nutrition 0.000 title claims abstract description 17
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 title abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 238000002156 mixing Methods 0.000 claims abstract description 8
- 229960003943 hypromellose Drugs 0.000 claims description 51
- 238000003756 stirring Methods 0.000 claims description 26
- 229920002678 cellulose Polymers 0.000 claims description 23
- 239000001913 cellulose Substances 0.000 claims description 23
- 238000009413 insulation Methods 0.000 claims description 14
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- 239000003292 glue Substances 0.000 claims description 11
- 238000005520 cutting process Methods 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000003814 drug Substances 0.000 abstract description 15
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 229940079593 drug Drugs 0.000 abstract description 6
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- 230000001133 acceleration Effects 0.000 abstract 1
- 235000013311 vegetables Nutrition 0.000 abstract 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 10
- 229920000159 gelatin Polymers 0.000 description 9
- 235000019322 gelatine Nutrition 0.000 description 9
- 108010010803 Gelatin Proteins 0.000 description 6
- 239000000499 gel Substances 0.000 description 6
- 239000008273 gelatin Substances 0.000 description 6
- 235000011852 gelatine desserts Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 239000001828 Gelatine Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 239000000463 material Substances 0.000 description 3
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- 238000011160 research Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000031295 Animal disease Diseases 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 208000007212 Foot-and-Mouth Disease Diseases 0.000 description 1
- 241000710198 Foot-and-mouth disease virus Species 0.000 description 1
- 208000018756 Variant Creutzfeldt-Jakob disease Diseases 0.000 description 1
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- 230000003213 activating effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 208000005881 bovine spongiform encephalopathy Diseases 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
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- 239000003795 chemical substances by application Substances 0.000 description 1
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- 235000013305 food Nutrition 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
- 206010048282 zoonosis Diseases 0.000 description 1
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- Medicinal Preparation (AREA)
Abstract
Description
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Priority Applications (1)
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CN201310346229.6A CN103394092B (zh) | 2013-08-11 | 2013-08-11 | 由结冷胶和氯化钙凝胶的羟丙甲纤维素肠溶空心胶囊 |
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CN201310346229.6A CN103394092B (zh) | 2013-08-11 | 2013-08-11 | 由结冷胶和氯化钙凝胶的羟丙甲纤维素肠溶空心胶囊 |
Publications (2)
Publication Number | Publication Date |
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CN103394092A CN103394092A (zh) | 2013-11-20 |
CN103394092B true CN103394092B (zh) | 2015-02-18 |
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CN201310346229.6A Active CN103394092B (zh) | 2013-08-11 | 2013-08-11 | 由结冷胶和氯化钙凝胶的羟丙甲纤维素肠溶空心胶囊 |
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Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105796375B (zh) * | 2014-12-31 | 2018-07-13 | 罗允俊 | 可携式清洁用品 |
CN106166143B (zh) * | 2016-06-22 | 2020-01-24 | 石家庄华加药用胶囊有限公司 | 一种植物硬空心胶囊壳及其制备方法 |
CN106924211B (zh) * | 2017-01-18 | 2019-10-08 | 浙江万里学院 | 一种肠溶空心胶囊及其制备方法 |
CN109771389B (zh) * | 2019-04-01 | 2020-02-14 | 重庆衡生药用胶囊有限公司 | 一种将钙盐和钠盐凝胶的羟丙甲纤维素肠溶空心胶囊 |
CN109846851B (zh) * | 2019-04-01 | 2021-01-01 | 重庆衡生药用胶囊有限公司 | 一种将钙盐、钾盐和钠盐凝胶的羟丙甲纤维素肠溶空心胶囊 |
CN109846852B (zh) * | 2019-04-01 | 2021-02-26 | 重庆衡生药用胶囊有限公司 | 一种将钾盐和钠盐凝胶的羟丙甲纤维素肠溶空心胶囊 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1292261A (zh) * | 1999-09-28 | 2001-04-25 | 上海大众凌伟生化股份有限公司 | 植物硬胶囊及其生产工艺 |
CN1343488A (zh) * | 2000-09-15 | 2002-04-10 | 付俊昌 | 一种胶囊体及其制备方法和用途 |
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2013
- 2013-08-11 CN CN201310346229.6A patent/CN103394092B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1292261A (zh) * | 1999-09-28 | 2001-04-25 | 上海大众凌伟生化股份有限公司 | 植物硬胶囊及其生产工艺 |
CN1343488A (zh) * | 2000-09-15 | 2002-04-10 | 付俊昌 | 一种胶囊体及其制备方法和用途 |
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Address after: 409000 Zhengyang Industrial Park Road, Qianjiang District, Chongqing city (No. 92) Patentee after: Chongqing Heng Sheng medicinal capsule Co., Ltd. Address before: 409000 Chongqing city Zhengyang Industrial Park Qianjiang District Park Road residential building 1 unit 1-B Bao (Biotech Pharmaceutical Capsule Corporation) Patentee before: Chongqing Hengsheng Capsules for Medicines Co., Ltd. |
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Effective date of registration: 20190115 Address after: 638599 Ding Ping Town (Industrial Concentration Development Zone), Lin Shui county, Guang'an, Sichuan. Patentee after: SICHUAN TIANSHENG PHARMACEUTICAL CO., LTD. Address before: No. 92 Park Road, Zhengyang Industrial Park (Hengsheng Pharmaceutical Capsule) Patentee before: Chongqing Heng Sheng medicinal capsule Co., Ltd. |