CN103355679A - Making method of chewable tablet with effect of enriching blood - Google Patents
Making method of chewable tablet with effect of enriching blood Download PDFInfo
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Abstract
The invention belongs to the technical field of food processing and specifically relates to a making method of a chewable tablet with an effect of enriching blood. The method comprises the following steps: (1) pretreatment of raw materials; (2) superfine grinding of red jujube; (3) preparation of auxiliary materials; (4) granulation; (5) tabletting; and (6) packaging and sterilization. According to the chewable tablet prepared by the above method, peanut skin is combined with jujube. The chewable tablets can nourish spleen and stomach, has a good effect of enriching blood, and is of great advantage for human health. In comparison with a common drying method, the making method by lyophilization is used to effectively reduce loss of nutritional ingredients and retain nutritional ingredients of red jujube to the maximum to make the nutritional ingredients to be absorbed and utilized by human body.
Description
Technical field
The invention belongs to food processing technology field, be specifically related to a kind of preparation method with chewable tablets of nourishing blood function.
Background technology
Peanut red coat is the accessory substance of peanut products, and China can both produce approximately 600 tons every year, is used for the pharmacy except a small amount of, and all the other all are used as feed, and its healthy nutritive value is not fully utilized.Peanut red coat has very abundant active component, and lipid, sterol, Jiao's property catechol tannin, phlobaphene, leucodelphindin etc. are arranged.Sweet, the little hardship of its flavor, property are put down, the effect that has styptic powder to become silted up.Peanut red coat can suppress fibrinous dissolving, increases hematoblastic content, improves hematoblastic quality, improves the defective of clotting factor, strengthens the contraction function of capillary, promotes the marrow hemopoiesis function.So the diseases such as the various hemorrhage and hemorrhage anaemias that cause, alpastic anemia are had positive effect.
Red date is bread and cheese, also is the medicine of commonly using, and eats for a long time or enters herbal cuisine, fills blood, the benefit taste, logical nine orifices, and hundred medicines, moisturizing beauty treatment, the strong will health care effect of prolonging life is the health fruit that integrates medicine, food, benefit 3 large functions, is described as " woody grain, excellent tonic product ".Red date contains 18 seed amino acids, the essential amino acid that wherein has 8 kinds of human bodies not synthesize, two seed amino acids that can not synthesize in child's body, i.e. arginine and thick propylhomoserin.Containing up to the citrin more than the 3300mg/100g, is the active ingredient of prevention and Hypertension.Red date is except common polysaccharide, flavones, alkaloid, cumarin etc., along with in recent years to the further investigation of red date functional component and pharmacology, find that red date contains also that some other fruit do not have or content seldom, but have the special bioactive ingredients of very high physiologically active.Pharmacological research shows that red date has the raising seralbumin, reduces blood cholesterol levels, the effects such as protection liver.Its CAMP can strengthen muscular strength, eliminates fatigue, hemangiectasis, increase myocardial contractive power, improve myocardial nutrition, and prevention and cure of cardiovascular disease is had good action.
Ultramicro grinding can be processed into sample micron order or nano level micro mist.The cold circulatory system in the crushing process can keep the nutritional labeling of peanut red coat and red date.Contain crude fibre in peanut red coat and the red date, after ultramicro grinding, its particle diameter diminishes, thereby effectively raises the dissolubility of scarlet and red date, and the active component in peanut red coat and the red date just more easily absorbs like this, has improved resource utilization.
Chewable tablets refers to by chewing or sucking the tablet preparation that clothes are swallowed after sheet is dissolved.Compare other product form, tablet preparation has outstanding advantage: easy to carry, take various informative; Absorb soon, the active material availability is high; Dispersity is good, and mouthfeel is easy to accept.By adding the materials such as some xylitols, milk can have additional nutrients composition and palatability.Even tablet preparation also can be taken under exsiccosis through after chewing, be particularly suitable for the elderly, child etc.The chewable tablets preparation not only is confined to medicine, also is widely applied aspect other at health food etc.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of mouthfeel good and have the preparation method of the chewable tablets of nourishing blood function, consist predominantly of peanut red coat in this chewable tablets, peanut red coat itself has good nourishing blood function, it is cooperated with red date, further play the effect of enriching blood.
Preparation method with chewable tablets of nourishing blood function comprises following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4-8% 50-60 ℃ of lower baking to its moisture, will through the peanut red coat ultramicro grinding of drying to the 500-1000 order, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the red date ultramicro grinding after the vacuum freezedrying to the 500-1000 order, got red date powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: peanut red coat powder 40-50 part, red date powder 20-30 part, sucrose 10-20 part, milk powder 6-10 part, xylitol 2-4 part, Arabic gum 1-3 part; Add in the above-mentioned raw material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to its pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the input of the raw material after the group of the pinching comminutor in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4-8%, and the particle that drying is good is crossed 14 mesh sieves, gets grain products;
(5) compressing tablet: add the dolomol of 1-3 part in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10～14min sterilization under the dosage of the radioactive source 5～9kGy of cobalt-60.
In the step (2), pulverize after adopting method of vacuum freeze drying to the red date freeze-drying, the principle of vacuum freezedrying and characteristics are identical with the drying principles under the normal pressure with the vacuum drying of food material, but because under vacuum state, the evaporating temperature of moisture is low than the evaporating temperature under the normal pressure, can effectively reduce the loss of nutritional labeling, adopt the mode of vacuum freeze drying to red date or the dry processing of matrimony vine, reduce the wherein loss of nutritional labeling.
The vacuum freeze drying principle: by physics as can be known, water has three-phase, and the O point is the three-phase concurrent, and OA is the melting point of ice.According to the principle that pressure reduces, boiling point descends, as long as pressure (pressure is below the 646.5Pa, and temperature is below 0 ℃) under three phase point pressure, the moisture in the material then can directly distil from water without liquid phase and be steam.Around this principle, just can be first the wet feed material of food be freezed under the freezing point, make the moisture in the raw material become solid ice, then under suitable vacuum environment, ice is converted into steam and removes, use again water vapour coagulator in the vacuum system with the water vapour condensation, thereby make material obtain drying.This method of utilizing vacuum refrigeration to obtain drying is that the states of matter of water changes and mobile process, and this process occurs under the low-temp low-pressure, and therefore, cryodesiccated basic principle is the mechanism of heat and mass under low-temp low-pressure.
The advantage of vacuum freeze drying is: because vacuum freeze drying carries out under low temperature, low pressure, and moisture directly distils, and therefore gives product many special performances.Also can dewater to heat sensitive material such as Vacuum Freezing ﹠ Drying Technology more thorough, and the medicine of drying is very stable, is convenient to long time stored.Because the drying of material is finished under frozen state, compares with other drying means, physical arrangement and the molecule structure change of material are minimum, and its institutional framework and mode of appearance are preserved preferably.In the vacuum freeze drying process, there is not surperficial sclerosis problem in material, and it inner forms the spongy of porous, thereby has excellent rehydration, can recover at short notice the state before dry.Because dry run is to carry out under very low temperature, and has substantially completely cut off air, therefore effectively suppress heat-sensitive substance biology, chemistry or physical change have occured, and preserved preferably the active material in the raw material, and the color and luster that has kept raw material.
Above-mentioned tablet press machine is the monolithic tablet press machine.
Above-mentioned comminutor is swing comminutor.
Preferably, the parts by weight of each above-mentioned raw material are as follows: 45 parts in peanut red coat powder, 25 parts of red date powders, 15 parts of sucrose, 8 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums, 2 parts of dolomols.
As a kind of improvement of the present invention, in take peanut red coat and red date as primary raw material, replenish again upper donkey-hide gelatin, matrimony vine, safflower; The combination of above material is not simply will have the invigorate blood circulation raw material of effect of enriching blood mutually to arrange in pairs or groups, and the combination of above component has synergy:
Anaemia or asthenia of qi and blood are thought on the theory of traditional Chinese medical science, all because of a little less than the taste, and why peanut red coat can reach the purpose of enriching blood, and is because the gas that peanut red coat can strengthen the spleen and stomach makes the better transporting of spleen, strengthen human body to the absorption of food, promote the hematopoiesis function of human body; The doctor trained in Western medicine theory thinks, peanut red coat can suppress fibrinous dissolving, increases hematoblastic content, improves hematoblastic quality, improves the defective of clotting factor, strengthens the contraction function of capillary, promotes the function of marrow hemopoiesis, thereby reaches the purpose of enriching blood;
The blood nourishing function of red date, because the polysaccharide component in the red date promotes hematopoiesis, the key of hematopoietic regulation is that candidate stem cell utilizes HPC, especially the acceptor that has occurred hemopoieticgrowth factor on latter's film, polysaccharide is the active ingredient that red date promotes hematopoiesis, its mechanism of action is by starting body hematopoietic regulation system, indirect stimulation candidate stem cell and proliferation of hematopoietic progenitors differentiation, polysaccharide in the red date is by improving the propagation of hematopoietic cell, differentiation, ripe hematopoieticmicroenviron-ment with having discharged important regulating and controlling effect, the direct or indirect macrophage of inducing and activating in the hematopoieticmicroenviron-ment, fibroblast, lymphocyte etc., or by indirect pathway stimulation skeletal muscle tissue in the body, make the higher erythroid hematopoiesis regulatory factor of their secretion activities, the hematopoietic regulation factor is regulated propagation and the differentiation of candidate stem cell and CFU-GM, promotes erythroid hematopoiesis.
Donkey-hide gelatin has significant facilitation to the red blood cell of animal, hemoglobin etc., can promote propagation and the differentiation of body candidate stem cell, with polysaccharide acting in conjunction in the red date in the candidate stem cell of body, and the effect of matrimony vine is, the effect of obvious promotion hematopoietic cell proliferation is arranged, can make Cervical mucus, strengthen the hematopoiesis function of human body, match with above-mentioned several raw materials, jointly promote the hematopoiesis function of body;
Safflower has the effect of invigorating blood circulation, qualcomm meridian, and qi and blood circulation promotion makes blood unimpeded, improves blood flow, promotes the hematopoiesis function of hematopoietic cell.Combine with above-mentioned raw material, not only further promote to enrich blood, and matrimony vine and croceous adding, can also eliminate donkey-hide gelatin itself with offending smell, make the chewable tablets mouthfeel better.
Method after the improvement is as follows:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4-8% 50-60 ℃ of lower baking to its moisture, will through the peanut red coat ultramicro grinding of drying to the 500-1000 order, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the red date ultramicro grinding after the vacuum freezedrying to the 500-1000 order, got red date powder;
The donkey-hide gelatin ultramicro grinding to the 500-1000 order, is got the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the ultramicro grinding after the vacuum freezedrying to the 500-1000 order, is got wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: peanut red coat powder 40-50 part, red date powder 20-30 part, donkey-hide gelatin powder 5-12 part, wolfberry fruit powder 5-15 part, sucrose 1-10 part, milk powder 6-10 part, xylitol 2-4 part, Arabic gum 1-3 part; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4-8%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add the dolomol of 1-3 part in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10～14min sterilization under the dosage of the radioactive source 5～9kGy of cobalt-60.
Preferably, the parts by weight of each raw material are as follows: 45 parts in peanut red coat powder, 25 parts of red date powders, 8 parts in donkey-hide gelatin powder, 10 parts of wolfberry fruit powder, 5 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums, 2 parts of dolomols.
Another kind of improved procedure is as follows, has the method for preparation method of the chewable tablets of nourishing blood function, comprises following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4-8% 50-60 ℃ of lower baking to its moisture, will through the peanut red coat ultramicro grinding of drying to the 500-1000 order, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the red date ultramicro grinding after the vacuum freezedrying to the 500-1000 order, got red date powder;
The donkey-hide gelatin ultramicro grinding to the 500-1000 order, is got the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the ultramicro grinding after the vacuum freezedrying to the 500-1000 order, is got wolfberry fruit powder;
The safflower ultramicro grinding to the 500-1000 order, is got saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: peanut red coat powder 40-50 part, red date powder 20-30 part, donkey-hide gelatin powder 5-12 part, wolfberry fruit powder 5-15 part, saffron 0.1-3 part, sucrose 1-10 part, milk powder 6-10 part, xylitol 2-4 part, Arabic gum 1-3 part; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4-8%,, the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add the dolomol of 1-3 part in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10～14min sterilization under the dosage of the radioactive source 5～9kGy of cobalt-60.
Preferably, the parts by weight of each raw material are as follows: 45 parts in peanut red coat powder, 25 parts of red date powders, 8 parts in donkey-hide gelatin powder, 10 parts of wolfberry fruit powder, 1 part of saffron, 5 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums, 2 parts of dolomols.
Preferably, have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 5% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 30Mpa in vacuum, vacuum freezedrying 8 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 2 parts of sucrose, 6 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
Preferably, have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 6% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 6000 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
With safflower ultramicro grinding to 600 order, get saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 1 part of saffron, 3 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%,, the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
Beneficial effect of the present invention is, the chewable tablets that adopts above-mentioned method to prepare, has the effect of enriching blood preferably, of great advantage to health, by to the red date vacuum freezedrying, compare with common drying mode, effectively reduced the loss of nutritional labeling, the reservation of larger limit the nutritional labeling of red date, it is remained, by human body is absorbed.
Clinical confirmation, peanut and date adapted can strengthen the effect of tonifying the blood and arrest bleeding, and, anaemia few for insufficiency of the spleen blood, thrombocytopenic purpura, hemophilia etc. have certain curative effect.
Chewable tablets quality of the present invention is crisp, comfortable taste, and without bad taste, instant has kept the active material in the various raw materials, has nourished energy and blood of human body.
In addition, among the present invention, donkey-hide gelatin, matrimony vine, safflower also in raw material, have been added, further strengthened its effect of enriching blood, and since added above-mentioned material, particularly matrimony vine itself with sweet taste, also improve the mouthfeel of chewable tablets, increased its acceptance.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Preparation method with chewable tablets of nourishing blood function comprises following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 6% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 15 parts of sucrose, 8 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned raw material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to its pinch can disperse after agglomerating till;
(4) granulation: the raw material after the group of pinching in the step (3) dropped into carry out granulation in the swing comminutor, the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 mesh sieves, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by monolithic tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
Observe tablet, its result is as follows:
Stability
Get tablet and put in the constant temperature hermetically closed container, being to place 10 days under about 90% the condition in relative humidity under 35 ℃, in sampling in the 5th day, the 10th day, the accurate reason amount of tablet before and after the weighing test was to investigate the wettability power of test sample;
Can find out from above-mentioned form, sample 1 in the tablet of the present invention, and in being to place 5 days under about 90% the condition in relative humidity under 35 ℃, its gain in weight is 1.19%, places after 10 days, increases weight 3.98%; Its stability better has stronger humidity-proof ability;
Sample 2 in the tablet of the present invention, and in being to place 5 days under about 90% the condition in relative humidity under 35 ℃, its gain in weight is 1.97%, places after 10 days, increases weight 4.98%; Its stability better has stronger humidity-proof ability;
Sample 3 in the tablet of the present invention, and in being to place 5 days under about 90% the condition in relative humidity under 35 ℃, its gain in weight is 1.58%, places after 10 days, increases weight 2.21%; Its stability better has stronger humidity-proof ability;
The chewable tablets of embodiment 1 is to the anaemia human feeding trial, dose is every twice-daily, each three, (every 1 gram), test crowd are 50 of 45-55 year women, other 50 women are control group, 100 women's content of hemoglobin is all less than 110g/l, and the time is 30 days, and the purpose of this test is, after taking chewable tablets to the experimenter, observe the content of hemoglobin in the subject, the increase of packed cell volume;
The situation of change of control group and tested group of content of hemoglobin (g/l)
As can be seen from the above results, take the chewable tablets that the present embodiment provides after, experimenter's hemoglobin increases obviously, value added is 27.8, this shows, the chewable tablets that the present embodiment provides has preferably nourishing blood function.
Embodiment 2
Preparation method with chewable tablets of nourishing blood function comprises following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4% 50 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 500 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours, red date ultramicro grinding to 500 order with after the vacuum freezedrying gets red date powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 40 parts in peanut red coat powder, 20 parts of red date powders, 10 parts of sucrose, 6 parts of milk powder, 2 parts of xylitols, 1 part of Arabic gum; Add in the above-mentioned raw material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to its pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the input of the raw material after the group of the pinching comminutor in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4%, and the particle that drying is good is crossed 14 mesh sieves, gets grain products;
(5) compressing tablet: add 1 part dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10min sterilization under the dosage of the radioactive source 5kGy of cobalt-60.
Embodiment 3
Preparation method with chewable tablets of nourishing blood function comprises following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 8% 60 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 1000 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 40Mpa in vacuum, vacuum freezedrying 12 hours, red date ultramicro grinding to 000 order with after the vacuum freezedrying gets red date powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 50 parts in peanut red coat powder, 30 parts of red date powders, 20 parts of sucrose, 10 parts of milk powder, 4 parts of xylitols, 3 parts of Arabic gums; Add in the above-mentioned raw material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to its pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the input of the raw material after the group of the pinching comminutor in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 8%, and the particle that drying is good is crossed 14 mesh sieves, gets grain products;
(5) compressing tablet: add 3 parts dolomol in the particle after sieving, by monolithic tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 14min sterilization under the dosage of the radioactive source 9kGy of cobalt-60.
Embodiment 4
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 6% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 4 parts of sucrose, 8 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
Embodiment 5
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 6% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 8 parts in donkey-hide gelatin powder, 10 parts of wolfberry fruit powder, 5 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
The chewable tablets of embodiment 5 is to the anaemia human feeding trial, dose is every twice-daily, each three, (every 1 gram), test crowd are 50 of 45-55 year women, other 50 women are control group, 100 women's content of hemoglobin is all less than 110g/l, and the time is 30 days, and the purpose of this test is, after taking chewable tablets to the experimenter, observe the content of hemoglobin in the subject, the increase of packed cell volume;
The situation of change of control group and tested group of content of hemoglobin (g/l)
Tested group women is after edible chewable tablets 30 days, and the value added average out to 35.9 of hemoglobin illustrates that above embodiment agree that stronger nourishing blood function is arranged.
Embodiment 6
Have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 5% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 30Mpa in vacuum, vacuum freezedrying 8 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 2 parts of sucrose, 6 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
Embodiment 7
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4% 50 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 500 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours, red date ultramicro grinding to 500 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 500 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours with the order of the ultramicro grinding to 500 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 40 parts in peanut red coat powder, 20 parts of red date powders, 5 parts in donkey-hide gelatin powder, 5 parts of wolfberry fruit powder, 1 part of sucrose, 6 parts of milk powder, 2 parts of xylitols, 1 part of Arabic gum; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 1 part dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10min sterilization under the dosage of the radioactive source 5kGy of cobalt-60.
Embodiment 8
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 8% 60 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 1000 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 40Mpa in vacuum, vacuum freezedrying 12 hours, red date ultramicro grinding to 1000 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 1000 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 40Mpa in vacuum, vacuum freezedrying 12 hours with the order of the ultramicro grinding to 1000 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 50 parts in peanut red coat powder, 30 parts of red date powders, 12 parts in donkey-hide gelatin powder, 15 parts of wolfberry fruit powder, 10 parts of sucrose, 10 parts of milk powder, 4 parts of xylitols, 3 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 8%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 3 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 14min sterilization under the dosage of the radioactive source 9kGy of cobalt-60.
Embodiment 9
Have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 6% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
With safflower ultramicro grinding to 600 order, get saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 1 part of saffron, 3 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%,, the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
In the following prepared chewable tablets of embodiment croceous composition is arranged, safflower has the effect of invigorating blood circulation, and has the chewable tablets of safflower composition, it should be noted when chewing: gynecologic menstrual, pregnancy period and functional bleeding phase do not take.
The chewable tablets of embodiment 9 is to the anaemia human feeding trial, dose is every twice-daily, each three, (every 1 gram), test crowd are 50 of 45-55 year women, other 50 women are control group, 100 women's content of hemoglobin is all less than 110g/l, and the time is 30 days, and the purpose of this test is, after taking chewable tablets to the experimenter, observe the content of hemoglobin in the subject, the increase of packed cell volume;
The situation of change of control group and tested group of content of hemoglobin (g/l)
Embodiment 10
Have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4% 50 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 500 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours, red date ultramicro grinding to 500 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 500 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours with the order of the ultramicro grinding to 500 after the vacuum freezedrying, gets wolfberry fruit powder;
With safflower ultramicro grinding to 500 order, get saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 40 parts in peanut red coat powder, 20 parts of red date powders, 5 parts in donkey-hide gelatin powder, 5 parts of wolfberry fruit powder, 0.5 part of saffron, 1 part of sucrose, 6 parts of milk powder, 2 parts of xylitols, 1 part of Arabic gum; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 1 part dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10min sterilization under the dosage of the radioactive source 5kGy of cobalt-60.
Embodiment 11
Have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 8% 60 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 1000 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 40Mpa in vacuum, vacuum freezedrying 12 hours, red date ultramicro grinding to 1000 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 1000 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 40Mpa in vacuum, vacuum freezedrying 12 hours with the order of the ultramicro grinding to 1000 after the vacuum freezedrying, gets wolfberry fruit powder;
With safflower ultramicro grinding to 1000 order, get saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 50 parts in peanut red coat powder, 30 parts of red date powders, 12 parts in donkey-hide gelatin powder, 15 parts of wolfberry fruit powder, 3 parts of saffrons, 10 parts of sucrose, 10 parts of milk powder, 4 parts of xylitols, 3 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 8%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 3 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 14min sterilization under the dosage of the radioactive source 9kGy of cobalt-60.
Embodiment 12
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4% 50 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 500 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours, red date ultramicro grinding to 500 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 500 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10Mpa in vacuum, vacuum freezedrying 4 hours with the order of the ultramicro grinding to 500 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 40 parts in peanut red coat powder, 20 parts of red date powders, 5 parts in donkey-hide gelatin powder, 5 parts of wolfberry fruit powder, 1 part of sucrose, 6 parts of milk powder, 2 parts of xylitols, 2 parts of active dry yeasrs, 1 part of Arabic gum; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 1 part dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10min sterilization under the dosage of the radioactive source 5kGy of cobalt-60.
Because it is digested that donkey-hide gelatin is not easy, and also embarrasses human body to absorb, because add active dry yeasr, help human body to the absorption of donkey-hide gelatin.
Claims (10)
1. the preparation method that has the chewable tablets of nourishing blood function comprises following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4-8% 50-60 ℃ of lower baking to its moisture, will through the peanut red coat ultramicro grinding of drying to the 500-1000 order, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the red date ultramicro grinding after the vacuum freezedrying to the 500-1000 order, got red date powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: peanut red coat powder 40-50 part, red date powder 20-30 part, sucrose 10-20 part, milk powder 6-10 part, xylitol 2-4 part, Arabic gum 1-3 part; Add in the above-mentioned raw material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to its pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the input of the raw material after the group of the pinching comminutor in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4-8%, and the particle that drying is good is crossed 14 mesh sieves, gets grain products;
(5) compressing tablet: add the dolomol of 1-3 part in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10～14min sterilization under the dosage of the radioactive source 5～9kGy of cobalt-60.
2. the method for the preparation method of the chewable tablets with nourishing blood function as claimed in claim 1 is characterized in that, described tablet press machine is the monolithic tablet press machine.
3. the method for the preparation method of the chewable tablets with nourishing blood function as claimed in claim 1 is characterized in that, described comminutor is swing comminutor.
4. the method for the preparation method of the chewable tablets with nourishing blood function as claimed in claim 1, it is characterized in that, the parts by weight of described each raw material are as follows: 45 parts in peanut red coat powder, 25 parts of red date powders, 15 parts of sucrose, 8 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums, 2 parts of dolomols.
5. have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4-8% 50-60 ℃ of lower baking to its moisture, will through the peanut red coat ultramicro grinding of drying to the 500-1000 order, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the red date ultramicro grinding after the vacuum freezedrying to the 500-1000 order, got red date powder;
The donkey-hide gelatin ultramicro grinding to the 500-1000 order, is got the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the ultramicro grinding after the vacuum freezedrying to the 500-1000 order, is got wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: peanut red coat powder 40-50 part, red date powder 20-30 part, donkey-hide gelatin powder 5-12 part, wolfberry fruit powder 5-15 part, sucrose 1-10 part, milk powder 6-10 part, xylitol 2-4 part, Arabic gum 1-3 part; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4-8%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add the dolomol of 1-3 part in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10～14min sterilization under the dosage of the radioactive source 5～9kGy of cobalt-60.
6. the method for the preparation method of the chewable tablets with nourishing blood function as claimed in claim 5, it is characterized in that, the parts by weight of described each raw material are as follows: 45 parts in peanut red coat powder, 25 parts of red date powders, 8 parts in donkey-hide gelatin powder, 10 parts of wolfberry fruit powder, 5 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums, 2 parts of dolomols.
7. have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 4-8% 50-60 ℃ of lower baking to its moisture, will through the peanut red coat ultramicro grinding of drying to the 500-1000 order, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the red date ultramicro grinding after the vacuum freezedrying to the 500-1000 order, got red date powder;
The donkey-hide gelatin ultramicro grinding to the 500-1000 order, is got the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 10-40Mpa in vacuum, vacuum freezedrying 4-12 hour, the ultramicro grinding after the vacuum freezedrying to the 500-1000 order, is got wolfberry fruit powder;
The safflower ultramicro grinding to the 500-1000 order, is got saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: peanut red coat powder 40-50 part, red date powder 20-30 part, donkey-hide gelatin powder 5-12 part, wolfberry fruit powder 5-15 part, saffron 0.1-3 part, sucrose 1-10 part, milk powder 6-10 part, xylitol 2-4 part, Arabic gum 1-3 part; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 4-8%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add the dolomol of 1-3 part in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 10～14min sterilization under the dosage of the radioactive source 5～9kGy of cobalt-60.
8. the method for the preparation method of the chewable tablets with nourishing blood function as claimed in claim 7, it is characterized in that, the parts by weight of described each raw material are as follows: 45 parts in peanut red coat powder, 25 parts of red date powders, 8 parts in donkey-hide gelatin powder, 10 parts of wolfberry fruit powder, 1 part of saffron, 5 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums, 2 parts of dolomols.
9. have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 5% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 600 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 30Mpa in vacuum, vacuum freezedrying 8 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 2 parts of sucrose, 6 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: carry out granulation in the material input comminutor with the group of pinching in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
10. have the method for preparation method of the chewable tablets of nourishing blood function, comprise following step:
(1) pretreatment of raw material: after the peanut red coat impurity elimination, be 6% 55 ℃ of lower baking to its moistures, will through peanut red coat ultramicro grinding to 6000 order of oven dry, get the peanut red coat powder;
(2) red date ultramicro grinding: with extracting red date stone, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours, red date ultramicro grinding to 600 order with after the vacuum freezedrying gets red date powder;
With donkey-hide gelatin ultramicro grinding to 600 order, get the donkey-hide gelatin powder;
With the matrimony vine vacuum freezedrying, be under the condition of 20Mpa in vacuum, vacuum freezedrying 6 hours with the order of the ultramicro grinding to 600 after the vacuum freezedrying, gets wolfberry fruit powder;
With safflower ultramicro grinding to 600 order, get saffron;
(3) preparation of softwood: material stirring is even, mix according to following parts by weight proportioning: 45 parts in peanut red coat powder, 25 parts of red date powders, 6 parts in donkey-hide gelatin powder, 8 parts of wolfberry fruit powder, 1 part of saffron, 3 parts of sucrose, 7 parts of milk powder, 3 parts of xylitols, 2 parts of Arabic gums; Add in the above-mentioned material with the ethanol of wetting agent 90%, the limit edged constantly stirs, to softwood pinch can disperse after agglomerating till;
(4) granulation: will carry out granulation in the material input comminutor of handling well in the step (3), the grain that then will make places the low-temperature vacuum drying case to be dried to moisture 6%, and the particle that drying is good is crossed 14 purposes sieve, gets grain products;
(5) compressing tablet: add 2 parts dolomol in the particle after sieving, by the tablet press machine compressing tablet, get tablet after mixing;
(6) packing and sterilization: the tablet that makes of packing, enter the sterilization of cobalt-60 equipment, the condition of sterilization is: irradiation 12min sterilization under the dosage of the radioactive source 8kGy of cobalt-60.
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| CN112998257A (en) * | 2021-03-29 | 2021-06-22 | 戴清桂 | Dietetic therapy composition and preparation method thereof |
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| CN115517350A (en) * | 2021-06-25 | 2022-12-27 | 中国农业大学 | A nutritional milk tablet containing protein and soluble fiber |
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| CN103859414A (en) * | 2014-04-09 | 2014-06-18 | 青岛博之源生物技术有限公司 | Blood-replenishing peanut protein powder and preparation method thereof |
| CN103859414B (en) * | 2014-04-09 | 2016-02-24 | 青岛博之源生物技术有限公司 | A kind of peanut protein powder of enriching blood and preparation method |
| CN105614426A (en) * | 2014-10-27 | 2016-06-01 | 卢雨萍 | Jasmine flower chewable tablet and preparation method thereof |
| CN104431686A (en) * | 2014-12-04 | 2015-03-25 | 中国科学院烟台海岸带研究所 | Selenium-enriched colla corii asini inulin chewable tablet and preparation method thereof |
| CN107616230A (en) * | 2017-10-30 | 2018-01-23 | 蔡达涛 | A kind of black peanut soybean milk drunk suitable for hyperpietic and preparation method thereof |
| CN108185100A (en) * | 2018-01-30 | 2018-06-22 | 江西省农业科学院 | One cultivates peanut oatmeal sugar and preparation method thereof |
| CN109567154A (en) * | 2018-10-29 | 2019-04-05 | 武威福民汇科技开发有限公司 | A kind of agaric red date, fresh ginger medlar health preserving compound nutritional chewable tablets and preparation method thereof |
| CN109645135A (en) * | 2019-01-21 | 2019-04-19 | 西北师范大学 | A kind of preparation method of fructus lycii donkey milk piece |
| CN111920028A (en) * | 2020-08-19 | 2020-11-13 | 河南省农业科学院农副产品加工研究中心 | Peanut skin honeyed pill and preparation method thereof |
| CN111920028B (en) * | 2020-08-19 | 2023-06-30 | 河南省农业科学院农副产品加工研究中心 | Peanut skin honey bolus and preparation method thereof |
| CN112998257A (en) * | 2021-03-29 | 2021-06-22 | 戴清桂 | Dietetic therapy composition and preparation method thereof |
| CN115517350A (en) * | 2021-06-25 | 2022-12-27 | 中国农业大学 | A nutritional milk tablet containing protein and soluble fiber |
| CN114766560A (en) * | 2022-04-08 | 2022-07-22 | 广西德星堂生物科技有限公司 | Oil tea soup material (powder) and preparation method thereof |
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