CN103328089B - 喷雾干燥技术 - Google Patents

喷雾干燥技术 Download PDF

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Publication number
CN103328089B
CN103328089B CN201180065313.XA CN201180065313A CN103328089B CN 103328089 B CN103328089 B CN 103328089B CN 201180065313 A CN201180065313 A CN 201180065313A CN 103328089 B CN103328089 B CN 103328089B
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CN
China
Prior art keywords
fluid
liquid
channel
channels
droplets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180065313.XA
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English (en)
Chinese (zh)
Other versions
CN103328089A (zh
Inventor
A·R·阿贝特
J·W·P·蒂尔勒
D·A·韦茨
M·温伯格斯
C·霍尔策
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Harvard University
Original Assignee
BASF SE
Harvard University
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Publication date
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Publication of CN103328089A publication Critical patent/CN103328089A/zh
Application granted granted Critical
Publication of CN103328089B publication Critical patent/CN103328089B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/18—Evaporating by spraying to obtain dry solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/10—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
    • F26B3/12—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray, i.e. sprayed or dispersed emulsions or suspensions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mechanical Engineering (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Drying Of Solid Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glanulating (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
CN201180065313.XA 2010-12-21 2011-12-20 喷雾干燥技术 Expired - Fee Related CN103328089B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061425415P 2010-12-21 2010-12-21
US61/425,415 2010-12-21
US201161485026P 2011-05-11 2011-05-11
US61/485,026 2011-05-11
PCT/US2011/001993 WO2012087350A2 (en) 2010-12-21 2011-12-20 Spray drying techniques

Publications (2)

Publication Number Publication Date
CN103328089A CN103328089A (zh) 2013-09-25
CN103328089B true CN103328089B (zh) 2016-09-07

Family

ID=45554781

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180065313.XA Expired - Fee Related CN103328089B (zh) 2010-12-21 2011-12-20 喷雾干燥技术

Country Status (5)

Country Link
US (2) US20120167410A1 (enExample)
EP (1) EP2654939A2 (enExample)
JP (2) JP2014508027A (enExample)
CN (1) CN103328089B (enExample)
WO (1) WO2012087350A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2706049T3 (es) * 2007-09-24 2019-03-27 Ziccum Ab Sistema y método para producir formulaciones secas
ES2384682T3 (es) * 2008-07-08 2012-07-10 Construction Research & Technology Gmbh Método para retirar agua de una mezcla
US8429831B2 (en) * 2009-09-04 2013-04-30 Abbott Cardiovascular Systems Inc. Drug-eluting coatings applied to medical devices by spraying and drying to remove solvent
CN104822447A (zh) * 2012-09-21 2015-08-05 哈佛学院院长及董事 用于微流体和其它系统中的喷雾干燥的系统和方法
EP3062900A4 (en) * 2013-10-29 2017-03-29 President and Fellows of Harvard College Drying techniques for microfluidic and other systems
DE102014004512A1 (de) * 2014-03-28 2015-10-01 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Bereich Universitätsmedizin Anorganisch-organische Hybridverbindung
PT107846B (pt) * 2014-08-01 2019-03-22 Hovione Farm S A Produção de nano- partículas de dispersões sólidas amorfas por co-precipitação controlada
EP3676548B1 (en) 2017-08-31 2023-05-10 Capsugel Belgium NV Method of spray drying using a single-use drying chamber
CN107715789B (zh) * 2017-10-23 2023-10-03 中国石油大学(北京) 一种制备聚合物颗粒的新方法及装置
DE102018205677A1 (de) * 2018-04-13 2019-10-17 Shukhrat Balabekov Vorrichtung und Verfahren zum Trocknen, Zerkleinern und Abscheiden von Trocknungsgut
CN108889762B (zh) * 2018-06-19 2020-12-25 刘悉承 一种制药工业废渣的处理方法
US20200078758A1 (en) 2018-09-07 2020-03-12 The Procter & Gamble Company Methods and Systems for Forming Microcapsules
US20200078759A1 (en) 2018-09-07 2020-03-12 The Procter & Gamble Company Methods and Systems for Forming Microcapsules
US20200078757A1 (en) 2018-09-07 2020-03-12 The Procter & Gamble Company Methods and Systems for Forming Microcapsules
WO2020092721A2 (en) * 2018-11-02 2020-05-07 Spraying Systems Co. Electrostatic spray dryer system
CN109557062A (zh) * 2018-12-10 2019-04-02 徐州工程学院 一种脱硫废水液滴蒸发测试装置及测试方法
IT201900008868A1 (it) * 2019-06-14 2019-09-14 Ur Fog S R L Sistema nebbiogeno dotato di dispositivi di sicurezza e di regolazione della portata del fluido nebbiogeno
CN110960504A (zh) * 2019-10-31 2020-04-07 上海新黄河制药有限公司 中空颗粒制备方法及干粉吸入制剂
CN112047791B (zh) * 2020-08-18 2022-05-27 南京理工大学 一种基于主动式微混合器的炸药连续制备系统及方法
US20230397620A1 (en) * 2022-06-08 2023-12-14 Bby, Inc. Powderization of Human Milk

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060163385A1 (en) * 2003-04-10 2006-07-27 Link Darren R Formation and control of fluidic species
WO2010110842A1 (en) * 2009-03-25 2010-09-30 Eastman Kodak Company Droplet generator

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2422804A (en) 1946-01-26 1947-06-24 Walter H Schroeder Kite
US5091122A (en) * 1988-03-24 1992-02-25 Idemitsu Kosan Company, Ltd. Method for microencapsulation of basic solutions
US5227018A (en) * 1989-09-26 1993-07-13 Niro A/S Gas distributor and heater for spray drying
US5236977A (en) * 1991-09-20 1993-08-17 National Starch And Chemical Investment Holding Corporation Corrugating adhesive containing soluble high amylose starch
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6187214B1 (en) * 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US5862808A (en) 1997-08-26 1999-01-26 Cigar Savor Enterprises Llc Cigar punch
WO2000061275A2 (de) * 1999-04-08 2000-10-19 Bernd Penth Verfahren und vorrichtung zur durchführung chemischer und physikalischer prozesse
US7351376B1 (en) * 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
AU2001290879A1 (en) * 2000-09-15 2002-03-26 California Institute Of Technology Microfabricated crossflow devices and methods
JP3746766B2 (ja) * 2001-02-23 2006-02-15 独立行政法人科学技術振興機構 エマルションの製造方法およびその装置
US7075162B2 (en) * 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
WO2003063822A2 (en) * 2002-02-01 2003-08-07 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
EP1403209A1 (en) * 2002-09-24 2004-03-31 The Technology Partnership Limited Fluid routing device
SE0300514D0 (sv) * 2003-02-26 2003-02-26 Astrazeneca Ab Powder generating apparatus and methods
US20060078893A1 (en) * 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
EP2662136A3 (en) 2003-08-27 2013-12-25 President and Fellows of Harvard College Method for handling and mixing droplets
BRPI0414082A (pt) * 2003-09-02 2006-10-24 Pfizer Prod Inc formas de dosagem de liberação sustentada de ziprasidona
JP5138223B2 (ja) * 2003-10-30 2013-02-06 サイトノーム エスティー リミテッド ライアビリティー カンパニー 流体力学的多層シースフロー構造
TW200536601A (en) * 2003-11-21 2005-11-16 Ebara Corp Micorfluidic treatment method and device
US20060121624A1 (en) * 2004-03-03 2006-06-08 Huang Lotien R Methods and systems for fluid delivery
US8741192B2 (en) * 2004-03-23 2014-06-03 Japan Science And Technology Agency Method and device for producing micro-droplets
US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7759111B2 (en) * 2004-08-27 2010-07-20 The Regents Of The University Of California Cell encapsulation microfluidic device
US20090269243A1 (en) * 2005-01-28 2009-10-29 Zymera, Inc. Electrically controlled microfluidic system
EP1861194A2 (en) 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
US7918244B2 (en) * 2005-05-02 2011-04-05 Massachusetts Institute Of Technology Microfluidic bubble logic devices
JP5001529B2 (ja) * 2005-06-10 2012-08-15 富士フイルム株式会社 有機顔料微粒子の製造方法
DE102005048259B4 (de) * 2005-10-07 2007-09-13 Landesstiftung Baden-Württemberg Vorrichtung und Verfahren zur Erzeugung eines Gemenges von zwei ineinander unlösbaren Phasen
FI120195B (fi) * 2005-11-16 2009-07-31 Canatu Oy Hiilinanoputket, jotka on funktionalisoitu kovalenttisesti sidotuilla fullereeneilla, menetelmä ja laitteisto niiden tuottamiseksi ja niiden komposiitit
WO2007057756A2 (en) * 2005-11-17 2007-05-24 Pfizer Limited Isocystene derivatives for the treatment of pain
DE602007009811D1 (de) 2006-01-27 2010-11-25 Harvard College Koaleszenz fluider tröpfchen
US7833804B2 (en) * 2006-04-14 2010-11-16 Wako Pure Chemical Industries, Ltd. Structure for introducing a plurality of solutions, micro fluidic device having said structure and method for introducing solution
EP2021113A2 (en) * 2006-05-11 2009-02-11 Raindance Technologies, Inc. Microfluidic devices
EP1884188A1 (de) * 2006-08-02 2008-02-06 F.Hoffmann-La Roche Ag Verpackung für einen Gegenstand mit hydrophiler Oberflächenbeschichtung
US20080166720A1 (en) * 2006-10-06 2008-07-10 The Regents Of The University Of California Method and apparatus for rapid nucleic acid analysis
JP4936880B2 (ja) * 2006-12-26 2012-05-23 株式会社東芝 ノズルプレート、ノズルプレートの製造方法、液滴吐出ヘッド及び液滴吐出装置
JP2008183554A (ja) * 2007-01-05 2008-08-14 Fujifilm Corp 有機微粒子分散液の製造方法、およびそれにより得られる有機微粒子
EP2125938A2 (en) * 2007-01-26 2009-12-02 Isp Investments Inc. Formulation process method to produce spray dried products
US7776927B2 (en) 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
DE102007026998A1 (de) * 2007-06-07 2008-12-11 Tesa Ag Hydrophiler Beschichtungslack
JP5040472B2 (ja) 2007-06-28 2012-10-03 富士通株式会社 表示制御装置、表示制御プログラム及び方法
GB0712860D0 (en) * 2007-07-03 2007-08-08 Eastman Kodak Co continuous inkjet drop generation device
US8883291B2 (en) 2007-08-07 2014-11-11 President And Fellows Of Harvard College Metal oxide coating on surfaces
US8802027B2 (en) 2008-03-28 2014-08-12 President And Fellows Of Harvard College Surfaces, including microfluidic channels, with controlled wetting properties
GB0810990D0 (en) * 2008-06-16 2008-07-23 Q Chip Ltd Device and method of making solid beads
WO2010002720A1 (en) 2008-07-03 2010-01-07 Adc Telecommunications, Inc. Telecommunications wire having a channeled dielectric insulator and methods for manufacturing the same
EP3290531B1 (en) 2008-12-19 2019-07-24 President and Fellows of Harvard College Particle-assisted nucleic acid sequencing
DE102009008478A1 (de) * 2009-02-11 2010-08-19 PHAST Gesellschaft für pharmazeutische Qualitätsstandards mbH Vorrichtung und Verfahren zur Herstellung pharmazeutisch hochfeiner Partikel sowie zur Beschichtung solcher Partikel in Mikroreaktoren
WO2010104604A1 (en) 2009-03-13 2010-09-16 President And Fellows Of Harvard College Method for the controlled creation of emulsions, including multiple emulsions
BRPI1008965B1 (pt) 2009-03-13 2018-12-18 Harvard College método para aumento de escala de dispositivos microfluídicos e sistema para a formação de gotículas em canais microfluídicos em paralelo
KR20110046867A (ko) * 2009-10-29 2011-05-06 삼성전자주식회사 기체 제공부를 포함하는 미세 유동 장치, 및 이를 이용한 액체 혼합 방법 및 에멀젼 형성 방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060163385A1 (en) * 2003-04-10 2006-07-27 Link Darren R Formation and control of fluidic species
WO2010110842A1 (en) * 2009-03-25 2010-09-30 Eastman Kodak Company Droplet generator

Also Published As

Publication number Publication date
US20160023126A1 (en) 2016-01-28
JP2016165721A (ja) 2016-09-15
EP2654939A2 (en) 2013-10-30
JP2014508027A (ja) 2014-04-03
CN103328089A (zh) 2013-09-25
WO2012087350A2 (en) 2012-06-28
WO2012087350A3 (en) 2012-08-16
US20120167410A1 (en) 2012-07-05

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160907

Termination date: 20181220

CF01 Termination of patent right due to non-payment of annual fee