JP2014508027A - 噴霧乾燥技術 - Google Patents

噴霧乾燥技術 Download PDF

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Publication number
JP2014508027A
JP2014508027A JP2013546100A JP2013546100A JP2014508027A JP 2014508027 A JP2014508027 A JP 2014508027A JP 2013546100 A JP2013546100 A JP 2013546100A JP 2013546100 A JP2013546100 A JP 2013546100A JP 2014508027 A JP2014508027 A JP 2014508027A
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JP
Japan
Prior art keywords
liquid
fluid
channel
less
spray dryer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013546100A
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English (en)
Japanese (ja)
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JP2014508027A5 (enExample
Inventor
アダム アール． アベイト，
ユリアン ヴェー．ペー． ティーレ，
デイビッド エー． ウェイツ，
マイケ ヴィントベルクス，
クリスティアン ホルツェ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
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Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University filed Critical Harvard University
Publication of JP2014508027A publication Critical patent/JP2014508027A/ja
Publication of JP2014508027A5 publication Critical patent/JP2014508027A5/ja
Pending legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/18—Evaporating by spraying to obtain dry solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B3/00—Drying solid materials or objects by processes involving the application of heat
    • F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
    • F26B3/10—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
    • F26B3/12—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray, i.e. sprayed or dispersed emulsions or suspensions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Drying Of Solid Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glanulating (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2013546100A 2010-12-21 2011-12-20 噴霧乾燥技術 Pending JP2014508027A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061425415P 2010-12-21 2010-12-21
US61/425,415 2010-12-21
US201161485026P 2011-05-11 2011-05-11
US61/485,026 2011-05-11
PCT/US2011/001993 WO2012087350A2 (en) 2010-12-21 2011-12-20 Spray drying techniques

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016044891A Division JP2016165721A (ja) 2010-12-21 2016-03-08 噴霧乾燥技術

Publications (2)

Publication Number Publication Date
JP2014508027A true JP2014508027A (ja) 2014-04-03
JP2014508027A5 JP2014508027A5 (enExample) 2015-02-05

Family

ID=45554781

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013546100A Pending JP2014508027A (ja) 2010-12-21 2011-12-20 噴霧乾燥技術
JP2016044891A Pending JP2016165721A (ja) 2010-12-21 2016-03-08 噴霧乾燥技術

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016044891A Pending JP2016165721A (ja) 2010-12-21 2016-03-08 噴霧乾燥技術

Country Status (5)

Country Link
US (2) US20120167410A1 (enExample)
EP (1) EP2654939A2 (enExample)
JP (2) JP2014508027A (enExample)
CN (1) CN103328089B (enExample)
WO (1) WO2012087350A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017513820A (ja) * 2014-03-28 2017-06-01 カールスルーエ インスティテュート フュア テクノロジ 無機有機ハイブリッド化合物
JP2017523205A (ja) * 2014-08-01 2017-08-17 ホビオネ インターナショナル エルティーディー 共沈によるサブミクロン範囲内の非晶質固体分散物の製造方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008305790B2 (en) * 2007-09-24 2012-08-09 Ziccum Ab System and method for producing dry formulations
US8584374B2 (en) * 2008-07-08 2013-11-19 Construction Research & Technology Gmbh Method for removing water from a mixture
US8429831B2 (en) 2009-09-04 2013-04-30 Abbott Cardiovascular Systems Inc. Drug-eluting coatings applied to medical devices by spraying and drying to remove solvent
CN104822447A (zh) * 2012-09-21 2015-08-05 哈佛学院院长及董事 用于微流体和其它系统中的喷雾干燥的系统和方法
WO2015066115A1 (en) * 2013-10-29 2015-05-07 President And Fellows Of Harvard College Drying techniques for microfluidic and other systems
WO2019043007A1 (en) 2017-08-31 2019-03-07 Capsugel Belgium Nv SINGLE-USE SPRAY DRYING COMPONENTS AND METHODS OF USE
CN107715789B (zh) * 2017-10-23 2023-10-03 中国石油大学(北京) 一种制备聚合物颗粒的新方法及装置
DE102018205677A1 (de) * 2018-04-13 2019-10-17 Shukhrat Balabekov Vorrichtung und Verfahren zum Trocknen, Zerkleinern und Abscheiden von Trocknungsgut
CN108889762B (zh) * 2018-06-19 2020-12-25 刘悉承 一种制药工业废渣的处理方法
US20200078758A1 (en) 2018-09-07 2020-03-12 The Procter & Gamble Company Methods and Systems for Forming Microcapsules
US20200078757A1 (en) 2018-09-07 2020-03-12 The Procter & Gamble Company Methods and Systems for Forming Microcapsules
US20200078759A1 (en) 2018-09-07 2020-03-12 The Procter & Gamble Company Methods and Systems for Forming Microcapsules
BR112021008254A2 (pt) * 2018-11-02 2021-08-03 Spraying Systems Co. sistema secador por pulverização eletrostática
CN109557062A (zh) * 2018-12-10 2019-04-02 徐州工程学院 一种脱硫废水液滴蒸发测试装置及测试方法
IT201900008868A1 (it) * 2019-06-14 2019-09-14 Ur Fog S R L Sistema nebbiogeno dotato di dispositivi di sicurezza e di regolazione della portata del fluido nebbiogeno
CN110960504A (zh) * 2019-10-31 2020-04-07 上海新黄河制药有限公司 中空颗粒制备方法及干粉吸入制剂
CN112047791B (zh) * 2020-08-18 2022-05-27 南京理工大学 一种基于主动式微混合器的炸药连续制备系统及方法
US20230397620A1 (en) * 2022-06-08 2023-12-14 Bby, Inc. Powderization of Human Milk

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002023163A1 (en) * 2000-09-15 2002-03-21 California Institute Of Technology Microfabricated crossflow devices and methods
US20060157129A1 (en) * 2002-09-24 2006-07-20 Somerville John M Fluid routing device
JP2006342304A (ja) * 2005-06-10 2006-12-21 Fujifilm Holdings Corp 有機顔料微粒子及びその製造方法
JP2008155591A (ja) * 2006-12-26 2008-07-10 Toshiba Corp ノズルプレート、ノズルプレートの製造方法、液滴吐出ヘッド及び液滴吐出装置
WO2010110842A1 (en) * 2009-03-25 2010-09-30 Eastman Kodak Company Droplet generator

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2422804A (en) 1946-01-26 1947-06-24 Walter H Schroeder Kite
US5091122A (en) * 1988-03-24 1992-02-25 Idemitsu Kosan Company, Ltd. Method for microencapsulation of basic solutions
US5227018A (en) * 1989-09-26 1993-07-13 Niro A/S Gas distributor and heater for spray drying
US5236977A (en) * 1991-09-20 1993-08-17 National Starch And Chemical Investment Holding Corporation Corrugating adhesive containing soluble high amylose starch
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6187214B1 (en) * 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US5862808A (en) 1997-08-26 1999-01-26 Cigar Savor Enterprises Llc Cigar punch
EP1165224B1 (de) * 1999-04-08 2002-09-18 Bernd Penth Verfahren und vorrichtung zur durchführung chemischer und physikalischer prozesse
US7351376B1 (en) * 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
EP1510251B1 (en) * 2001-02-23 2006-09-06 Japan Science and Technology Agency Process and apparatus for producing microcapsules
US7075162B2 (en) * 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
PT1469833T (pt) * 2002-02-01 2021-07-13 Bend Res Inc Método para produzir dispersões de fármaco amorfo sólido seco por pulverização homogéneas utilizando aparelho de secagem por pulverização modificado
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
SE0300514D0 (sv) * 2003-02-26 2003-02-26 Astrazeneca Ab Powder generating apparatus and methods
US20060078893A1 (en) * 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
EP2266687A3 (en) * 2003-04-10 2011-06-29 The President and Fellows of Harvard College Formation and control of fluidic species
WO2005021151A1 (en) 2003-08-27 2005-03-10 President And Fellows Of Harvard College Electronic control of fluidic species
MXPA06002455A (es) * 2003-09-02 2006-08-31 Pfizer Prod Inc Formas de dosificacion de liberacion sostenida de ziprasidona.
BRPI0415913B1 (pt) * 2003-10-30 2017-09-26 Cytonome/St, Llc Structure and flow system for suspending a particle and method for wrapping that particle on at least two sides by a involving fluid
TW200702660A (en) * 2003-11-21 2007-01-16 Ebara Corp Microfluidic treatment method and device
US20060121624A1 (en) * 2004-03-03 2006-06-08 Huang Lotien R Methods and systems for fluid delivery
EP1757357B1 (en) * 2004-03-23 2013-04-24 Japan Science and Technology Agency Method and device for producing micro-droplets
US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7759111B2 (en) * 2004-08-27 2010-07-20 The Regents Of The University Of California Cell encapsulation microfluidic device
US20090269243A1 (en) * 2005-01-28 2009-10-29 Zymera, Inc. Electrically controlled microfluidic system
EP2248578B1 (en) 2005-03-04 2012-06-06 President and Fellows of Harvard College Method for forming multiple emulsions
US7918244B2 (en) * 2005-05-02 2011-04-05 Massachusetts Institute Of Technology Microfluidic bubble logic devices
DE102005048259B4 (de) * 2005-10-07 2007-09-13 Landesstiftung Baden-Württemberg Vorrichtung und Verfahren zur Erzeugung eines Gemenges von zwei ineinander unlösbaren Phasen
FI120195B (fi) * 2005-11-16 2009-07-31 Canatu Oy Hiilinanoputket, jotka on funktionalisoitu kovalenttisesti sidotuilla fullereeneilla, menetelmä ja laitteisto niiden tuottamiseksi ja niiden komposiitit
EP1954260A2 (en) * 2005-11-17 2008-08-13 Pfizer Limited Isocystene derivatives for the treatment of pain
EP2004316B8 (en) 2006-01-27 2011-04-13 President and Fellows of Harvard College Fluidic droplet coalescence
WO2007121263A2 (en) * 2006-04-14 2007-10-25 Wako Pure Chemical Industries, Ltd Structure for introducing a plurality of solutions, micro fluidic device having said structure and method for introducing solution
US20080014589A1 (en) * 2006-05-11 2008-01-17 Link Darren R Microfluidic devices and methods of use thereof
EP1884188A1 (de) * 2006-08-02 2008-02-06 F.Hoffmann-La Roche Ag Verpackung für einen Gegenstand mit hydrophiler Oberflächenbeschichtung
US20080166720A1 (en) * 2006-10-06 2008-07-10 The Regents Of The University Of California Method and apparatus for rapid nucleic acid analysis
JP2008183554A (ja) * 2007-01-05 2008-08-14 Fujifilm Corp 有機微粒子分散液の製造方法、およびそれにより得られる有機微粒子
JP5508859B2 (ja) * 2007-01-26 2014-06-04 アイエスピー インヴェストメンツ インコーポレイテッド 噴霧乾燥製品を製造するための調剤処理方法
US7776927B2 (en) 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
DE102007026998A1 (de) * 2007-06-07 2008-12-11 Tesa Ag Hydrophiler Beschichtungslack
JP5040472B2 (ja) 2007-06-28 2012-10-03 富士通株式会社 表示制御装置、表示制御プログラム及び方法
GB0712860D0 (en) * 2007-07-03 2007-08-08 Eastman Kodak Co continuous inkjet drop generation device
WO2009020633A2 (en) 2007-08-07 2009-02-12 President And Fellows Of Harvard College Metal oxide coating on surfaces
EP2271581A4 (en) 2008-03-28 2014-09-03 Harvard College MICROFLUID CHANNELS CONTAINING SURFACES WITH CONTROLLED WETTING CHARACTERISTICS
GB0810990D0 (en) * 2008-06-16 2008-07-23 Q Chip Ltd Device and method of making solid beads
WO2010002720A1 (en) 2008-07-03 2010-01-07 Adc Telecommunications, Inc. Telecommunications wire having a channeled dielectric insulator and methods for manufacturing the same
WO2010080134A1 (en) 2008-12-19 2010-07-15 President And Fellows Of Harvard College Particle-assisted nucleic acid sequencing
DE102009008478A1 (de) * 2009-02-11 2010-08-19 PHAST Gesellschaft für pharmazeutische Qualitätsstandards mbH Vorrichtung und Verfahren zur Herstellung pharmazeutisch hochfeiner Partikel sowie zur Beschichtung solcher Partikel in Mikroreaktoren
US9056299B2 (en) 2009-03-13 2015-06-16 President And Fellows Of Harvard College Scale-up of flow-focusing microfluidic devices
WO2010104604A1 (en) 2009-03-13 2010-09-16 President And Fellows Of Harvard College Method for the controlled creation of emulsions, including multiple emulsions
KR20110046867A (ko) * 2009-10-29 2011-05-06 삼성전자주식회사 기체 제공부를 포함하는 미세 유동 장치, 및 이를 이용한 액체 혼합 방법 및 에멀젼 형성 방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002023163A1 (en) * 2000-09-15 2002-03-21 California Institute Of Technology Microfabricated crossflow devices and methods
US20060157129A1 (en) * 2002-09-24 2006-07-20 Somerville John M Fluid routing device
JP2006342304A (ja) * 2005-06-10 2006-12-21 Fujifilm Holdings Corp 有機顔料微粒子及びその製造方法
JP2008155591A (ja) * 2006-12-26 2008-07-10 Toshiba Corp ノズルプレート、ノズルプレートの製造方法、液滴吐出ヘッド及び液滴吐出装置
WO2010110842A1 (en) * 2009-03-25 2010-09-30 Eastman Kodak Company Droplet generator

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6015049361; Ｄｒｙｉｎｇ　Ｔｅｃｈｎｏｌｏｇｙ Ｖｏｌ．２５，　Ｎｏ．１０／１２, 200710, ｐ．１９０７-１９１６ *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017513820A (ja) * 2014-03-28 2017-06-01 カールスルーエ インスティテュート フュア テクノロジ 無機有機ハイブリッド化合物
JP2017523205A (ja) * 2014-08-01 2017-08-17 ホビオネ インターナショナル エルティーディー 共沈によるサブミクロン範囲内の非晶質固体分散物の製造方法
JP2020183426A (ja) * 2014-08-01 2020-11-12 ホビオネ インターナショナル エルティーディー 共沈によるサブミクロン範囲内の非晶質固体分散物の製造方法
JP2023012459A (ja) * 2014-08-01 2023-01-25 ホビオネ インターナショナル エルティーディー 共沈によるサブミクロン範囲内の非晶質固体分散物の製造方法

Also Published As

Publication number Publication date
US20120167410A1 (en) 2012-07-05
CN103328089B (zh) 2016-09-07
WO2012087350A3 (en) 2012-08-16
EP2654939A2 (en) 2013-10-30
JP2016165721A (ja) 2016-09-15
CN103328089A (zh) 2013-09-25
US20160023126A1 (en) 2016-01-28
WO2012087350A2 (en) 2012-06-28

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