CN103169756B - 一种注射用水溶性维生素、脂溶性维生素注射液和脂肪乳注射液的药物组合物 - Google Patents
一种注射用水溶性维生素、脂溶性维生素注射液和脂肪乳注射液的药物组合物 Download PDFInfo
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- CN103169756B CN103169756B CN201310044348.6A CN201310044348A CN103169756B CN 103169756 B CN103169756 B CN 103169756B CN 201310044348 A CN201310044348 A CN 201310044348A CN 103169756 B CN103169756 B CN 103169756B
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- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 description 1
- 235000019136 lipoic acid Nutrition 0.000 description 1
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- 235000019192 riboflavin Nutrition 0.000 description 1
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- 150000003839 salts Chemical class 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
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Images
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
组分 | 组合1 | 组合2 | 组合3 | 组合4 | 组合5 | 组合6 | 组合7 | 组合8 |
维生素A | 0.69mg | 0.67mg | 0.68mg | 0.99mg | 0.98mg | 0.98mg | 0.69mg | 0.98mg |
维生素E | 6.4mg | 6.3mg | 6.4mg | 9.0mg | 9.1mg | 9.0mg | 6.4mg | 9.1mg |
维生素D2 | 9.9μg | 10.0μg | 9.9μg | 5.0μg | 4.9μg | 4.9μg | 9.8μg | 4.8μg |
维生素K1 | 0.2mg | 0.19mg | 0.19mg | 0.14mg | 0.15mg | 0.14mg | 0.19mg | 0.15mg |
维生素B1 | 3.1mg | 3.0mg | 3.1mg | 3.0mg | 2.9mg | 3.0mg | 3.0mg | 3.1mg |
维生素B2 | 4.8mg | 4.8mg | 4.9mg | 4.9mg | 4.8mg | 4.7mg | 4.7mg | 4.6mg |
烟酰胺 | 39mg | 40mg | 39mg | 38mg | 39mg | 40mg | 38mg | 36mg |
维生素B6 | 4.8mg | 4.7mg | 4.9mg | 4.7mg | 4.9mg | 4.8mg | 4.7mg | 4.8mg |
泛酸钠 | 16.4mg | 16.5mg | 16.4mg | 16.5mg | 16.4mg | 16.4mg | 16.3mg | 16.4mg |
维生素C钠 | 113mg | 112mg | 111mg | 112mg | 113mg | 112mg | 110mg | 111mg |
生物素 | 60μg | 60μg | 58μg | 58μg | 59μg | 60μg | 58μg | 57μg |
叶酸 | 0.39mg | 0.40mg | 0.38mg | 0.38mg | 0.39mg | 0.39mg | 0.37mg | 0.36mg |
维生素B12 | 4.9μg | 5.0μg | 4.8μg | 4.8μg | 4.9μg | 4.8μg | 4.8μg | 4.7μg |
性状 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 |
pH值 | 7.8 | 7.9 | 7.9 | 7.8 | 7.8 | 7.9 | 7.9 | 7.8 |
组分 | 组合1 | 组合2 | 组合3 | 组合4 | 组合5 | 组合6 | 组合7 | 组合8 |
维生素A | 0.68mg | 0.67mg | 0.68mg | 0.98mg | 0.97mg | 0.98mg | 0.66mg | 0.95mg |
维生素E | 6.4mg | 6.3mg | 6.3mg | 8.9mg | 9.0mg | 9.0mg | 6.1mg | 8.6mg |
维生素D2 | 9.8μg | 9.9μg | 9.8μg | 4.9μg | 4.8μg | 4.8μg | 9.3μg | 4.3μg |
维生素K1 | 0.19mg | 0.18mg | 0.18mg | 0.16mg | 0.15mg | 0.14mg | 0.17mg | 0.11mg |
维生素B1 | 3.0mg | 2.9mg | 3.0mg | 2.9mg | 2.9mg | 2.9mg | 2.4mg | 2.5mg |
维生素B2 | 4.8mg | 4.7mg | 4.8mg | 4.9mg | 4.7mg | 4.7mg | 4.3mg | 4.2mg |
烟酰胺 | 38mg | 39mg | 38mg | 37mg | 37mg | 39mg | 29mg | 30mg |
维生素B6 | 4.7mg | 4.6mg | 4.7mg | 4.6mg | 4.8mg | 4.7mg | 4.0mg | 4.1mg |
泛酸钠 | 16.4mg | 16.5mg | 16.2mg | 16.4mg | 16.2mg | 16.3mg | 14.3mg | 14.4mg |
维生素C钠 | 112mg | 112mg | 110mg | 112mg | 111mg | 112mg | 86mg | 88mg |
生物素 | 60μg | 59μg | 58μg | 57μg | 59μg | 60μg | 51μg | 50μg |
叶酸 | 0.38mg | 0.39mg | 0.38mg | 0.37mg | 0.38mg | 0.39mg | 0.29mg | 0.28mg |
维生素B12 | 4.9μg | 5.0μg | 4.9μg | 4.8μg | 4.9μg | 4.7μg | 3.5μg | 3.7μg |
性状 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 | 微黄乳状液 |
pH值 | 7.8 | 7.9 | 7.9 | 7.8 | 7.8 | 7.9 | 7.6 | 7.5 |
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CN103768088B (zh) * | 2014-02-18 | 2015-03-11 | 海南圣欣医药科技有限公司 | 一种含注射用水溶性维生素、注射用脂溶性维生素和中/长链脂肪乳注射液的药物组合物 |
CN103768132B (zh) * | 2014-02-18 | 2015-03-11 | 海南圣欣医药科技有限公司 | 一种含注射用水溶性维生素、脂溶性维生素注射液和中/长链脂肪乳注射液的药物组合物 |
US10656059B2 (en) | 2018-03-07 | 2020-05-19 | Alcala Pharmaceutical, Inc. | Method for qualitative and quantitative multiplexing of drug analytes from biological samples |
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CN102429864A (zh) * | 2011-11-29 | 2012-05-02 | 海南灵康制药有限公司 | 一种脂溶性维生素注射液(ii)和注射用水溶性维生素的药物组合物及其制法 |
CN102512437A (zh) * | 2011-11-29 | 2012-06-27 | 海南美兰史克制药有限公司 | 一种脂溶性维生素注射液(i)和注射用水溶性维生素的药物组合物及其制法 |
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CN102512437A (zh) * | 2011-11-29 | 2012-06-27 | 海南美兰史克制药有限公司 | 一种脂溶性维生素注射液(i)和注射用水溶性维生素的药物组合物及其制法 |
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