CN103103175A - 新型腈水合酶 - Google Patents
新型腈水合酶 Download PDFInfo
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- CN103103175A CN103103175A CN2012105742761A CN201210574276A CN103103175A CN 103103175 A CN103103175 A CN 103103175A CN 2012105742761 A CN2012105742761 A CN 2012105742761A CN 201210574276 A CN201210574276 A CN 201210574276A CN 103103175 A CN103103175 A CN 103103175A
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- nitrile hydratase
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP368360/2002 | 2002-12-19 | ||
| JP2002368360A JP2004194588A (ja) | 2002-12-19 | 2002-12-19 | 新規なニトリルヒドラターゼ |
| JP2003379280 | 2003-11-10 | ||
| JP379280/2003 | 2003-11-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2003801069930A Division CN1729288A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103103175A true CN103103175A (zh) | 2013-05-15 |
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| CNA2003801069930A Pending CN1729288A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
| CN2012105742117A Pending CN103215242A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
| CN2012105742761A Pending CN103103175A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
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| CN2010101672031A Pending CN101892211A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
| CNA2003801069930A Pending CN1729288A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
| CN2012105742117A Pending CN103215242A (zh) | 2002-12-19 | 2003-12-15 | 新型腈水合酶 |
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| US (1) | US7595184B2 (https=) |
| EP (1) | EP1586637B1 (https=) |
| JP (1) | JP2004194588A (https=) |
| KR (5) | KR100819228B1 (https=) |
| CN (4) | CN101892211A (https=) |
| AU (2) | AU2003289338A1 (https=) |
| WO (1) | WO2004056990A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112322606A (zh) * | 2020-11-20 | 2021-02-05 | 江南大学 | 一种腈水合酶突变体及其应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1767624B1 (en) * | 2004-05-26 | 2013-11-06 | Mitsubishi Rayon Co., Ltd. | Improved nitrile hydratase |
| EP1842907A1 (en) | 2006-04-07 | 2007-10-10 | B.R.A.I.N. Ag | A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity |
| JP5069032B2 (ja) * | 2007-04-04 | 2012-11-07 | ダイヤニトリックス株式会社 | 改良型ニトリルヒドラターゼ |
| AU2009315170C1 (en) * | 2008-11-14 | 2014-10-23 | Mitsui Chemicals, Inc. | Nitrile hydratase variant |
| JP5532618B2 (ja) * | 2009-01-30 | 2014-06-25 | 三菱レイヨン株式会社 | 改良型ニトリルヒドラターゼ及びその製造方法 |
| WO2010125829A1 (ja) | 2009-04-30 | 2010-11-04 | 三井化学株式会社 | ３-メルカプトプロピオン酸またはその塩を製造する方法 |
| KR101734797B1 (ko) | 2011-05-31 | 2017-05-24 | 미쯔비시 케미컬 주식회사 | 개량형 니트릴 히드라타제 |
| US9193966B2 (en) | 2011-06-07 | 2015-11-24 | Mitsubishi Rayon Co., Ltd. | Nitrile hydratase |
| CN102517271B (zh) * | 2011-12-13 | 2013-04-03 | 清华大学 | 一种突变腈水合酶 |
| CN112941060B (zh) | 2014-06-06 | 2025-05-09 | 三菱化学株式会社 | 改良型腈水合酶 |
| CN104725476B (zh) * | 2015-03-31 | 2018-10-16 | 清华大学 | 一种钩状结构寡肽及其应用 |
| AU2017388945B2 (en) * | 2016-12-28 | 2021-06-03 | Mitsui Chemicals, Inc. | Mutant nitrile hydratase, nucleic acid coding said mutant nitrile hydratase, expression vector and transformant including said nucleic acid, production method for said mutant nitrile hydratase, and production method for amide compound |
| KR20190049109A (ko) | 2017-11-01 | 2019-05-09 | (주)대화정공 | 풀리 제조방법 |
| KR102068615B1 (ko) | 2019-04-08 | 2020-01-21 | (주)대화정공 | 자동차 댐퍼풀리 제조방법 |
| KR102146408B1 (ko) | 2019-04-08 | 2020-08-21 | (주)대화정공 | 단류선 개선을 위해 압연롤러를 이용한 자동차 댐퍼풀리 제조방법 |
| CN111690675B (zh) * | 2019-08-01 | 2022-07-19 | 安徽瑞邦生物科技有限公司 | 一种表达腈水合酶突变体的重组菌及其制备方法和应用 |
| CN112522245A (zh) * | 2020-12-09 | 2021-03-19 | 江南大学 | 一种腈水合酶氨基酸基序的改造及其应用 |
| CN113151234B (zh) * | 2021-04-13 | 2022-08-12 | 浙江工业大学 | 腈水合酶赖氨酸突变体hba-k2h2r、编码基因及应用 |
| CN113444714B (zh) * | 2021-07-29 | 2022-06-21 | 浙江大学杭州国际科创中心 | 一种β亚基突变的腈水合酶突变体及其应用 |
| CN114317507B (zh) * | 2021-11-30 | 2024-07-02 | 清华大学 | 腈水合酶突变体及其应用 |
| CN119343452A (zh) * | 2022-06-30 | 2025-01-21 | 三井化学株式会社 | 突变型腈水合酶、编码该突变型腈水合酶的核酸、含有该核酸的载体及转化体、该突变型腈水合酶的制造方法、及酰胺化合物的制造方法 |
| CN115772514B (zh) * | 2022-11-03 | 2025-03-04 | 无锡新晨宇生物工程有限公司 | 一种腈水合酶底物通道氨基酸基序的改造用于肉桂酰胺的制备 |
| EP4600368A1 (en) * | 2024-02-09 | 2025-08-13 | Adisseo France S.A.S. | A method for enzymatic production of an amide compound |
Citations (1)
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| JPH09275978A (ja) * | 1996-02-14 | 1997-10-28 | Mitsui Toatsu Chem Inc | 新規なニトリルヒドラターゼ |
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|---|---|---|---|---|
| MX169933B (es) | 1987-09-18 | 1993-08-02 | Hideaki Yamada | Procedimiento para la produccion biologica de amidas |
| AU627648B2 (en) | 1990-02-28 | 1992-08-27 | Teruhiko Beppu | Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant |
| JPH0856684A (ja) | 1994-08-16 | 1996-03-05 | Mitsui Toatsu Chem Inc | 微生物によるアミド化合物の製造法 |
| CN1240833C (zh) | 1996-02-14 | 2006-02-08 | 三井化学株式会社 | 新型腈水合酶 |
| JP3408737B2 (ja) * | 1998-03-16 | 2003-05-19 | 三井化学株式会社 | ニトリルヒドラターゼの活性化に関与するタンパク質及びそれをコードする遺伝子 |
-
2002
- 2002-12-19 JP JP2002368360A patent/JP2004194588A/ja active Pending
-
2003
- 2003-12-15 AU AU2003289338A patent/AU2003289338A1/en not_active Abandoned
- 2003-12-15 CN CN2010101672031A patent/CN101892211A/zh active Pending
- 2003-12-15 CN CNA2003801069930A patent/CN1729288A/zh active Pending
- 2003-12-15 KR KR1020077024119A patent/KR100819228B1/ko not_active Expired - Lifetime
- 2003-12-15 KR KR1020057011335A patent/KR100825147B1/ko not_active Expired - Lifetime
- 2003-12-15 KR KR1020077015994A patent/KR100794001B1/ko not_active Expired - Lifetime
- 2003-12-15 EP EP03780752.6A patent/EP1586637B1/en not_active Expired - Lifetime
- 2003-12-15 CN CN2012105742117A patent/CN103215242A/zh active Pending
- 2003-12-15 US US10/539,560 patent/US7595184B2/en not_active Expired - Lifetime
- 2003-12-15 KR KR1020067026866A patent/KR100785548B1/ko not_active Expired - Lifetime
- 2003-12-15 KR KR1020067026865A patent/KR100785549B1/ko not_active Expired - Lifetime
- 2003-12-15 WO PCT/JP2003/016014 patent/WO2004056990A1/ja not_active Ceased
- 2003-12-15 CN CN2012105742761A patent/CN103103175A/zh active Pending
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- 2010-06-28 AU AU2010202683A patent/AU2010202683B2/en not_active Expired
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09275978A (ja) * | 1996-02-14 | 1997-10-28 | Mitsui Toatsu Chem Inc | 新規なニトリルヒドラターゼ |
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| AKIMASA MIYANAGA,ET AL: "Crystal Structure of Cobalt-Containing Nitrile Hydratase", 《BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112322606A (zh) * | 2020-11-20 | 2021-02-05 | 江南大学 | 一种腈水合酶突变体及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070007393A (ko) | 2007-01-15 |
| EP1586637B1 (en) | 2014-02-26 |
| WO2004056990A1 (ja) | 2004-07-08 |
| AU2010202683B2 (en) | 2012-01-19 |
| KR100785549B1 (ko) | 2007-12-12 |
| AU2010202683A1 (en) | 2010-07-15 |
| KR20070110146A (ko) | 2007-11-15 |
| KR100819228B1 (ko) | 2008-04-03 |
| JP2004194588A (ja) | 2004-07-15 |
| KR100794001B1 (ko) | 2008-01-10 |
| CN103215242A (zh) | 2013-07-24 |
| EP1586637A4 (en) | 2008-03-19 |
| EP1586637A1 (en) | 2005-10-19 |
| KR100785548B1 (ko) | 2007-12-12 |
| KR20070087054A (ko) | 2007-08-27 |
| US7595184B2 (en) | 2009-09-29 |
| KR100825147B1 (ko) | 2008-04-24 |
| KR20050089972A (ko) | 2005-09-09 |
| AU2003289338A1 (en) | 2004-07-14 |
| KR20070011620A (ko) | 2007-01-24 |
| US20070009985A1 (en) | 2007-01-11 |
| CN1729288A (zh) | 2006-02-01 |
| CN101892211A (zh) | 2010-11-24 |
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