CN103097369A - 化学合成安卓幸的方法及其抑制非小细胞肺癌的应用 - Google Patents

化学合成安卓幸的方法及其抑制非小细胞肺癌的应用 Download PDF

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Publication number
CN103097369A
CN103097369A CN2011800294118A CN201180029411A CN103097369A CN 103097369 A CN103097369 A CN 103097369A CN 2011800294118 A CN2011800294118 A CN 2011800294118A CN 201180029411 A CN201180029411 A CN 201180029411A CN 103097369 A CN103097369 A CN 103097369A
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compound
lung cancer
reacting
small cell
android
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CN103097369B (zh
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杨震
曾耀铭
李闯创
罗佗平
石航
叶淇台
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)

Abstract

提供一种化学全合成制备安卓幸的方法以及一种包含安卓幸或其医药上可接受盐类与医药上可接受载体的组合物在制备用于抑制非小细胞肺癌细胞生长的药物中的应用。

Description

PCT国内申请，说明书已公开。

Claims (27)

  1. PCT国内申请，权利要求书已公开。
CN201180029411.8A 2011-08-10 2011-08-10 化学合成安卓幸的方法及其抑制非小细胞肺癌的应用 Expired - Fee Related CN103097369B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2011/078232 WO2013020285A1 (zh) 2011-08-10 2011-08-10 化学合成安卓幸的方法及其抑制非小细胞肺癌的应用

Publications (2)

Publication Number Publication Date
CN103097369A true CN103097369A (zh) 2013-05-08
CN103097369B CN103097369B (zh) 2014-09-17

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CN201180029411.8A Expired - Fee Related CN103097369B (zh) 2011-08-10 2011-08-10 化学合成安卓幸的方法及其抑制非小细胞肺癌的应用

Country Status (5)

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US (1) US9045450B2 (zh)
EP (1) EP2746268B1 (zh)
JP (1) JP5890524B2 (zh)
CN (1) CN103097369B (zh)
WO (1) WO2013020285A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109432442A (zh) * 2018-11-19 2019-03-08 上海健康医学院 Slfn5或slfn5促进剂在制备肺癌治疗药物中的用途

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9603882B2 (en) * 2013-08-13 2017-03-28 Industrial Technology Research Institute Method for modulating Th17 cells and method for treating a disease related to modulation of Th17 cells
CN106659765B (zh) 2014-04-04 2021-08-13 德玛医药 二脱水半乳糖醇及其类似物或衍生物用于治疗非小细胞肺癌和卵巢癌的用途
US20170189418A1 (en) * 2015-12-30 2017-07-06 Ma Shen Kai Ruei Co., Ltd. Pharmaceutical composition for treating lung cancer
CN109700799A (zh) * 2018-07-06 2019-05-03 北京大学深圳研究生院 牛樟芝素及其微纳米颗粒在制备肿瘤免疫治疗药物中的应用
WO2021161593A1 (ja) 2020-02-10 2021-08-19 ユニマテック株式会社 含フッ素重合体を有効成分とする柔軟性撥水撥油剤

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461687A (en) * 1980-12-06 1984-07-24 Studiengesellschaft Kohle Mbh Processes for the preparation of pure enantiomers of bicyclo(2,2,2)oct-5-en-2-ones

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070116787A1 (en) * 2005-11-21 2007-05-24 Chih-Jung Yao Cancer treatment
TW200918498A (en) * 2007-10-19 2009-05-01 Golden Biotechnology Corp Novel compound isolated from Antrodia camphorate extracts
CN102204902B (zh) * 2010-03-29 2014-07-16 朝阳科技大学 用于抑制癌细胞生长的含安卓幸的药学组成物
US8580847B2 (en) * 2010-04-26 2013-11-12 Chaoyang University Of Technology Antrocin containing pharmaceutical compositions for inhibiting cancer cells
US20110263700A1 (en) * 2010-04-26 2011-10-27 Chaoyang University Of Technology Antrocin containing pharmaceutical compositions for inhibiting cancer cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4461687A (en) * 1980-12-06 1984-07-24 Studiengesellschaft Kohle Mbh Processes for the preparation of pure enantiomers of bicyclo(2,2,2)oct-5-en-2-ones

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHIANG HUNG-CHEN 等: "A Sesquiterpene Lactone, Phenyl and Biphenyl Compounds from Antrodia Cinnamomea", 《PHYTOCHEMISTRY》, vol. 39, no. 3, 30 June 1995 (1995-06-30), pages 613 - 616, XP008138393, DOI: doi:10.1016/0031-9422(95)00025-3 *
RAO YERRA KOTESWARA ET AL.: "Identification of Antrocin from Antrodia Camphorata as a Selective and Novel Class of Small Molecule Inhibitor of Akt/mTOR Signaling in Metastatic Breast Cancer MDA-MB-231 Cells", 《CHEM.RES.TOXICOL.》, vol. 24, no. 2, 15 December 2010 (2010-12-15), pages 238 - 245, XP055143239, DOI: doi:10.1021/tx100318m *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109432442A (zh) * 2018-11-19 2019-03-08 上海健康医学院 Slfn5或slfn5促进剂在制备肺癌治疗药物中的用途

Also Published As

Publication number Publication date
WO2013020285A1 (zh) 2013-02-14
US20140350096A1 (en) 2014-11-27
EP2746268A1 (en) 2014-06-25
JP2014524421A (ja) 2014-09-22
JP5890524B2 (ja) 2016-03-22
US9045450B2 (en) 2015-06-02
EP2746268A4 (en) 2015-09-16
EP2746268B1 (en) 2016-12-07
CN103097369B (zh) 2014-09-17

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