CN102988229A - Treatment process of radix scrophulariae and preparation process of radix scrophulariae based cosmetic - Google Patents
Treatment process of radix scrophulariae and preparation process of radix scrophulariae based cosmetic Download PDFInfo
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Abstract
The invention relates to a treatment process of radix scrophulariae and a preparation process of a radix scrophulariae based cosmetic. The preparation process of the radix scrophulariae based cosmetic is as follows: adding 1 to 20wt% of radix scrophulariae extract during the process of preparing the cosmetic, wherein the radix scrophulariae extract is the ginsenoside material which is prepared by the treatment process of the radix scrophulariae, including the steps of adopting korean ginseng as the raw material, stewing and drying in sun at nine times, and then extracting. The radix scrophulariae based cosmetic, prepared by the process provided by the invention, has no components harmful to the skin, and can expel toxins, eliminate abscess, smoothen blackspot, prevent pigmented naevus and fade spots, so as to improve the skin texture, homogenize the color of skin, remove the flaws, and whiten the skin; and the radix scrophulariae based cosmetic also can centrally provide sufficient moisture and nutrition to the skin, and specifically has remarkable effects of resisting oxidation, removing wrinkles and preventing ageing.
Description
Technical field
The invention belongs to the cosmetics technical field, relate to Radix Ginseng and extract the application of composition in cosmetics, relate to particularly a kind of preparation technology for the treatment of process and black ginseng cosmetics of black ginseng.
Background technology
Radix Ginseng is Araliaceae Panax's herbaceos perennial, is described as " king of BAICAO " from ancient times.In Shennong's Herbal just by record can " tonifying five ZANG-organs, peace spirit, decide soul, spasmolytic throb with fear, except pathogen, happy Fructus Alpiniae Oxyphyllae makes eye bright ", " take to make light of one's life by commiting suicide for a long time and prolong life ".Li Shizhen (1518-1593 A.D.) is also very praised highly Radix Ginseng in Compendium of Material Medica, thinks that it can " control all deficient syndromes of male woman ".Radix Ginseng all is listed in " top grade " in Chinese herbal medicine for thousands of years.So Radix Ginseng is famous and precious, just be that its medical value is high, truly have the effect of building body, life prolonging.Modern medicine study and assay show, main active in the Radix Ginseng is that a class is known as the chemical substance of " ginsenoside (ginsenoside; GS) ", the latter has the balance the body central nervous system, affects multiple metabolic pathway, improves body immunity, heart tonifying, resisting fatigue, the anti-ageing obvious effect of having waited for a long time, and for the various diseases of nervous system, cardiovascular system, hormonal system and reproductive system good therapeutical effect is arranged all.
Radix Ginseng can be divided into polytype again according to the difference of processing stage: water ginseng: in the ground after the extraction without the Radix Ginseng of any processing; Trepang: water is joined dried product; Radix Ginseng: the product of dry gained again after the peeling of water ginseng; Radix Ginseng Rubra: steam to well done with high-temperature steam after first the water ginseng being cleaned under the state of not peeling epidermis off, dry again the bronzing product of gained, its ginsenoside's in the process that cooks contamination all increases, and the ginsenoside Rg3 of anticancer effect occurred having; Black ginseng: water ginseng or Radix Ginseng Rubra through more than 7 times cook with dry after the black product of (so-called nine steam nine shines) gained, wherein the ginsenoside ginsenoside Rg3 that particularly has an anticancer effect to beat again than Radix Ginseng Rubra be to increase, so medical value is higher.
CN101442913A discloses the manufacture method of a kind of black ginseng, black ginseng concentrated solution and the black ginseng right fruit.Wherein, black ginseng manufacture method as raw material, comprise washing with the water ginseng, cook, the operations such as maturation, the immobilization of raw material form and drying.Black ginseng concentrated solution manufacture method comprises washing, cooks, maturation, the immobilization of raw material form, extraction, filtration, concentrated, purify and the operation such as concentrate.Black ginseng right fruit manufacture method comprise to raw material wash successively, surface moisture is dry with the epidermis membrane removal, be placed on the porous disc, nine times comprise and be followed successively by dipping Mel, cook and the operation of maturation, for the first time dry, finishing raw material, for the second time drying and packaging process.
CN102238878A disclose a kind of to Radix Ginseng Rubra and water ginseng ferment the fermented red ginseng of ripening and fermented black ginseng with and manufacture method.Described fermentation process carries out with stable and gentle condition, comprising: (a) add in Radix Ginseng the natural fruits that comprises Fructus Armeniacae Mume is fermented and the native enzyme liquid that obtains, simultaneously in the step of 40-80 ℃ of bottom fermentation ripening 50-360h; And (b) Radix Ginseng through the fermentation maturation stage of (a) is implemented hot blast damp process and gravity-flow ventilation simultaneously, and under 35-60 ℃, cook the step of ripening 160-720h.Active constituent content absorbed by the body increases in the fermented ginseng that this invention is made, and owing to do not carry out high-temperature process, effective ingredient does not substantially have loss or degeneration can not occur.
The present invention finds that in early-stage Study the ginsenoside in the black ginseng particularly ginsenoside Rg3 has significant skin-care effect, has broad application prospects at cosmetic field.
Summary of the invention
One of the object of the invention is, provides a kind for the treatment of process of black ginseng to process nine steamings, nine tanned ginsengs, therefrom extracts black ginseng elite composition; Two of the object of the invention is that the black ginseng elite composition that further will extract is applied to cosmetics, thereby a kind of preparation technology of black ginseng cosmetics is provided.
For one of achieving the above object, the present invention adopts following technical scheme:
A kind for the treatment of process of black ginseng comprises the steps:
(1) nine steams the processing of nine tanned ginsengs:
1. gather koryo insam, clean up.
Famous ginseng for medicinal use mainly is distributed in the north, the Korea peninsula, Northeast China and Russian Siberian east in the world.Described koryo insam is the Radix Ginseng that refers to that specially the Korea peninsula produces, wherein contain now 34 kinds of ginsenosides of clear and definite structure, compare and descend, contain in China Radix Ginseng (Radix Notoginseng) and contain 14 kinds of ginsenosides in 15 kinds of ginsenosides, the U.S.'s Radix Ginseng (Radix Panacis Quinquefolii) and only contain 8 kinds of ginsenosides in the Japan, koryo insam is enjoyed great prestige in the world with its abundant ginsenoside's contamination.
Among the present invention take koryo insam as raw material, for abundant material base has been established in the processing of black ginseng and ginsenoside's extraction.
Preferably, koryo insam described in the present invention is the koryo insam that trophophase reaches 4-6, trophophase at this moment between koryo insam in the section ripe, the content of ginsenoside that contains simultaneously is high.
Most preferably, koryo insam described in the present invention is the koryo insam that trophophase reached 6 years, and ginsenoside's content is the highest in the koryo insam of this moment.
Described cleaning should be noted not injuring the original shape of koryo insam or lose its composition.
2. steam for the first time and shine: under 50 ℃-70 ℃ temperature, the koryo insam after 1. step cleaned cooks 1.5-3.5h, then dry 70-140h under 20 ℃-40 ℃ temperature.
Described 50 ℃-70 ℃ for example can be 50 ℃-64.2 ℃, 53.8 ℃-59.7 ℃, 61 ℃-70 ℃, 50 ℃, 51.3 ℃, 52 ℃, 54.5 ℃, 55 ℃, 57.4 ℃, 58 ℃, 60 ℃, 60.3 ℃, 62 ℃, 63.2 ℃, 65 ℃, 67.5 ℃, 68 ℃, 69.1 ℃, 70 ℃; Be preferably 55-65 ℃; Most preferably be 60 ℃.
Described 1.5-3.5h for example can be 1.5-2.1h, 1.85-3.07h, 2.9-3.5h, 1.5h, 1.69h, 1.75h, 2h, 2.2h, 2.46h, 2.5h, 2.8h, 3h, 3.13h, 3.25h, 3.4h, 3.5h; Be preferably 2-3h; Most preferably be 2.5h.
Described 20 ℃-40 ℃ for example can be 20 ℃-34.2 ℃, 23.8 ℃-39.7 ℃, 31 ℃-40 ℃, 20 ℃, 20.3 ℃, 22 ℃, 23.2 ℃, 25 ℃, 27.5 ℃, 28 ℃, 29.1 ℃, 30 ℃, 30.8 ℃, 32 ℃, 34.5 ℃, 35 ℃, 37.4 ℃, 38 ℃, 40 ℃; Be preferably 25-35 ℃; Most preferably be 30 ℃.
Described 70-140h for example can be 70-101h, 85-127h, 99-140h, 70h, 75h, 80.5h, 83h, 89.2h, 90h, 95h, 100h, 113h, 120h, 122h, 134h, 137.5h, 140h; Be preferably 90-120h; Most preferably be 108h.
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs.
After steaming for the second time the solarization end, visible Radix Ginseng begins to present redness.
After end was shone in the 7th steaming, visible Radix Ginseng began to present black.
After end was shone in the 8th steaming, visible Radix Ginseng had substantially all become black.
After end was shone in the 9th steaming, nine steam nine tanned participation workers finished.
Steam the process of shining above-mentioned 9 times, steam each time the appearance color that shines rear Radix Ginseng and change as shown in Figure 1.
Carry out nine and steam nine solarizations under cryogenic conditions, can prevent the generation of carcinogen benzopyrene, the black ginseng stability that obtains is better, and the shelf-life is longer.
After steaming nine solarizations through nine, original toxic component is removed in the koryo insam, nine steam and also to have formed ginsenoside Rh2, ginsenoside Rg1, the ginsenoside Rg3 who does not have in the former koryo insam in the nine tanned ginsengs and have anti-inflammation, prevent that the content of menthol composition, particularly ginsenoside Rg3 of aging action and the Radix Ginseng Rubra that absorbance compares all are significantly increased.
The content of ginsenoside in black ginseng and the Radix Ginseng Rubra is compared, the result as shown in Figure 2, as seen deceive the content of ginsenoside Rg1, ginsenoside Rg3, ginsenoside Rb1, ginsenoside Rb2, Ginsenoside Rc, ginsenoside Rd in the ginseng all than being significantly improved in the Radix Ginseng Rubra, the content that particularly wherein has the ginsenoside Rg3 of anticancer effect will be higher than Radix Ginseng Rubra far away, has also produced simultaneously the ginsenoside Rh1 and the ginsenoside Rh2's composition that do not have in the Radix Ginseng Rubra.
It is as follows now to deceive the ginsenoside's composition and the effect brief introduction that mainly contain in the ginseng:
The ginsenoside Ro: but antiinflammatory, detoxifcation, inhibition acid are that platelet is condensed and activated macrophage, have the effects such as anti-hepatitis, antithrombotic, detoxifcation antiinflammatory.
Ginsenoside Rb1: can strengthen the function of choline system, the synthetic and release of increase acetylcholine, have the effects such as the memory of improvement, antipyretic-antalgic, liver function protecting.
The ginsenoside Rb2: can promote DNA, RNA synthetic, reduce intracellular calcium content, remove interior free yl, antioxidation, have arteriosclerosis, improve the effect such as myocardial ischemia reperfusion injury.
Ginsenoside Rb3: can strengthen myocardial function, protection human body autoimmune system.
Ginsenoside Rc: have the effects such as analgesia, promotion protein and lipid synthesis, anticancer.
Ginsenoside Rd: promote the effect of adrenal cortex hormone secretion;
The ginsenoside Re: the liver protective effect promotes the medullary cell anabolic effect;
The ginsenoside Rf: the brain cell analgesic activity, suppress lipid peroxidation;
Ginsenoside Rg: can promote the synthetic of DNA, RNA, have the effects such as stimulating central nervous system, resisting fatigue, improvement memory and learning capacity.
The ginsenoside Rg1: but stimulating central nervous system, suppress platelet aggregation, have rapid recovery fatigue, improve learning and memory function, the effect such as slow down aging.
Ginsenoside Rg2: can suppress platelet aggregation, improve myocardial ischemia and anoxia fast, have the memory of improvement, prevent and treat coronary heart disease, the effect such as shock.
Ginsenoside Rg3: the G2 phase that can act on the germiparity cycle, protein and ATP's is synthetic mitosis prophase of anticancer, the proliferate speed of cancerous cell is slowed down, and have the effects such as anticancer infiltrates, antitumor cell shifts, promotion apoptosis of tumor cells, inhibition tumor cell growth.
The ginsenoside Rh: have suppress nervus centralis, hypnosis, ease pain, calm the nerves, analgesic, promote the effects such as serum proteins are synthetic.
Ginsenoside Rh1: can promote hepatocyte growth, promote that DNA is synthetic, suppress platelet aggregation, have protect the liver, the effect such as antitumor.
Ginsenoside Rh2: have anticancer propagation and shift, suppress tumor proliferation, enhancing human body immunity power, recover the effect such as body constitution rapidly.
Wherein, the ginsenoside Rg3 is because shifting closely related with apoptosis of tumor cells and tumor cell, to obtain to pay close attention to one of maximum ginsenoside, its chemical structural formula as shown in Figure 3, and the present invention finds in early-stage Study, the ginsenoside Rg3 can significantly improve skin immunization power, recover skin elasticity, has significantly crease-resistant and defying age effect, considers that thus the main active Ginsenosides material that will extract in the black ginseng is applied among the cosmetics.
(2) acquisition of black conopsea extraction:
1. with step (1) nine steaming nine tanned ginsengs to join its quality 10-30 concentration doubly be in the 1,3 butylene glycol of 20wt%-40wt% 3., remove by filter impurity after fully reacting 0.5-3h.
Described 10-30 doubly, for example can be 10-17.5 doubly, 13.6-24.9 doubly, 21-30 doubly, 10 times, 11.5 times, 12 times, 14.7 times, 15 times, 16.8 times, 17 times, 18 times, 19.2 times, 20 times, 22.5 times, 23 times, 25 times, 26.3 times, 27 times, 28.1 times, 29.5 times, 30 times; Be preferably 15-25 doubly; Most preferably be 20 times.
Described concentration is 20wt%-40wt%, for example can be 20wt%-32.5wt%, 27-37wt%, 24.7-38.8wt%, 20wt%, 22wt%, 23.4wt%, 25wt%, 26.1wt%, 28wt%, 29.6wt%, 30wt%, 31wt%, 33.2wt%, 35wt%, 36.5wt%, 39.3wt%, 40wt%; Be preferably 25wt%-35wt%; Most preferably be 30wt%.
Described 0.5-3h for example can be 0.5-1.1h, 0.85-2.07h, 1.9-3h, 0.5h, 0.73h, 0.95h, 1h, 1.25h, 1.4h, 1.5h, 1.69h, 1.75h, 2h, 2.2h, 2.46h, 2.5h, 2.8h, 3h; Be preferably 1-2h; Most preferably be 1.5h.
2. repeating step operation 1. is 2-5 time.
Described 2-5 time for example can be 2 times, 3 times, 4 times, 5 times, is preferably 3-4 time, most preferably is 3 times.
3. vacuum concentration step product 2. under 40 ℃-60 ℃ the temperature, the ethanol that adds its quality 20-40 concentration doubly and be 70wt% dilutes.
Described 40 ℃-60 ℃ for example can be 40 ℃-54.2 ℃, 43.8 ℃-59.7 ℃, 51 ℃-60 ℃, 40 ℃, 41.3 ℃, 42 ℃, 44.5 ℃, 45 ℃, 47.4 ℃, 48 ℃, 50 ℃, 50.3 ℃, 52 ℃, 53.2 ℃, 55 ℃, 57.5 ℃, 58 ℃, 59.1 ℃, 60 ℃; Be preferably 45-55 ℃; Most preferably be 50 ℃.
Described 20-40 doubly, for example can be 20-27.5 doubly, 23.6-34.9 doubly, 31-40 doubly, 20 times, 22.5 times, 23 times, 25 times, 26.3 times, 27 times, 28.1 times, 29.5 times, 30 times, 31.5 times, 32 times, 34.7 times, 35 times, 36.8 times, 37 times, 38 times, 39.2 times, 40 times; Be preferably 25-35 doubly; Most preferably be 30 times.
4. the antiseptic that adds its quality 0.2wt%-2wt% in the step product 3..
Described 0.2wt%-2wt% for example can be 0.2wt%-0.84wt%, 0.6wt%-1.47wt%, 1.1wt%-2wt%, 0.2wt%, 0.35wt%, 0.4wt%, 0.49wt%, 0.5wt%, 0.65wt%, 0.7wt%, 0.8wt%, 0.91wt%, 1wt%, 1.06wt%, 1.2wt%, 1.35wt%, 1.4wt%, 1.54wt%, 1.6wt%, 1.7wt%, 1.8wt%, 1.86wt%, 1.9wt%, 2wt%; Be preferably 0.5wt%-1.5wt%; Most preferably be 1wt%.
Preferably, the select oneself combination of any one or at least two kinds in glycol, Flos Magnoliae glycol, the tropolone of described antiseptic, described combination for example can be from hexanediol/Flos Magnoliae glycol, Flos Magnoliae glycol/tropolone, hexanediol/tropolone, hexanediol/Flos Magnoliae glycol/tropolone.
In sum, concrete technical scheme of the present invention is as follows:
A kind for the treatment of process of black ginseng comprises the steps:
(1) nine steams the processing of nine tanned ginsengs:
1. gather koryo insam, clean up;
2. steam for the first time and shine: under 50 ℃-70 ℃ temperature, the koryo insam after 1. step cleaned cooks 1.5-3.5h, then dry 70-140h under 20 ℃-40 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
(2) acquisition of black conopsea extraction:
1. with step (1) nine steaming nine tanned ginsengs to join its quality 10-30 concentration doubly be in the 1,3 butylene glycol of 20wt%-40wt% 3., remove by filter impurity after fully reacting 0.5-3h;
2. repeating step operation 1. is 2-5 time;
3. vacuum concentration step product 2. under 40 ℃-60 ℃ the temperature, the ethanol that adds its quality 20-40 concentration doubly and be 70wt% dilutes;
4. the select oneself combination of any one or at least two kinds in glycol, Flos Magnoliae glycol, the tropolone of the antiseptic that adds its quality 0.2wt%-2wt% in the step product 3., described antiseptic.
Technical scheme after the present invention optimizes is as follows:
A kind for the treatment of process of black ginseng comprises the steps:
(1) nine steams the processing of nine tanned ginsengs:
1. gather the koryo insam that trophophase reaches 4-6, clean up;
2. steam for the first time and shine: under 55 ℃-65 ℃ temperature, the koryo insam after 1. step cleaned cooks 2-3h, then dry 90-120h under 25 ℃-35 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
(2) acquisition of black conopsea extraction:
1. with step (1) nine steaming nine tanned ginsengs to join its quality 15-25 concentration doubly be in the 1,3 butylene glycol of 25wt%-35wt% 3., remove by filter impurity after fully reacting 1-2h;
2. repeating step operation 1. is 3-4 time;
3. vacuum concentration step product 2. under 45 ℃-55 ℃ the temperature, the ethanol that adds its quality 25-35 concentration doubly and be 70wt% dilutes;
4. the select oneself combination of any one or at least two kinds in glycol, Flos Magnoliae glycol, the tropolone of the antiseptic that adds its quality 0.5wt%-1.5wt% in the step product 3., described antiseptic.
The technical scheme of optimum of the present invention is as follows:
A kind for the treatment of process of black ginseng comprises the steps:
(1) nine steams the processing of nine tanned ginsengs:
1. gather the koryo insam that trophophase reaches 6 years, clean up;
2. steam for the first time and shine: under 60 ℃ temperature, the koryo insam after 1. step cleaned cooks 2.5h, then dry 108h under 30 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
(2) acquisition of black conopsea extraction:
1. with step (1) 3. nine to steam the concentration that nine tanned ginsengs join 20 times of its quality be in the 1,3 butylene glycol of 30wt%, remove by filter impurity after fully reacting 1.5h;
2. repeating step operation 1. is 3 times;
3. vacuum concentration step product 2. under 50 ℃ the temperature, the concentration that adds 30 times of its quality is that the ethanol of 70wt% dilutes;
4. the select oneself combination of any one or at least two kinds in glycol, Flos Magnoliae glycol, the tropolone of the antiseptic that adds its quality 1wt% in the step product 3., described antiseptic.
For achieve the above object two, the present invention adopts following technical scheme:
A kind of preparation technology of black ginseng cosmetics, adding content in preparation process is the black conopsea extraction of 1wt%-20wt%.
Described 1wt%-20wt% for example can be 1wt%-8wt%, 4.5wt%-12.6wt%, 11.5wt%-20wt%, 1wt%, 2wt%, 2.5wt%, 3wt%, 3.1wt%, 3.6wt%, 4wt%, 5wt%, 5.4wt%, 6wt%, 6.7wt%, 7.5wt%, 9wt%, 9.2wt%, 10wt%, 11.3wt%, 12wt%, 14wt%, 15wt%, 16.9wt%, 18wt%, 19wt%, 20wt%; Be preferably 3wt%-15wt%; Most preferably be 5wt%-10wt%.
In sum, the technical scheme after the present invention optimizes is as follows:
A kind of preparation technology of black ginseng cosmetics, adding content in preparation process is the black conopsea extraction of 3wt%-15wt%;
The technical scheme of optimum of the present invention is as follows:
A kind of preparation technology of black ginseng cosmetics, adding content in preparation process is the black conopsea extraction of 5wt%-10wt%.
All expression technological parameters that use in description and claims, constituent content, reaction condition etc. all are appreciated that the modification that adds term " about " in all cases.Therefore, unless point out on the contrary, in description and claims given numerical value can be according to the present invention the desired character that obtains different and changing.At bottom line, and be not used in the scope that the application of equivalent principle is defined as claim, each numerical value should be at least according to the value of the significant digits of reporting by using common rounding method to make an explanation.And all scopes in this announcement all are appreciated that starting point and the end point values that comprises scope, comprise arbitrarily and all are included in wherein among a small circle.For example, certain scope " 1-10 " should be considered to comprise any of (being included) between minima 1 and the maximum 10 and all among a small circle; Namely all are initial with the minima more than or equal to 1, and be less than or equal to that 10 maximum finishes all among a small circle, 2-7 for example, 3.9-5.4, or 8.5-9.8.
Compared with prior art, the preparation technology of black ginseng cosmetics of the present invention has added in the preparation process of cosmetics and has had remarkable antioxidation, antiinflammatory, the black conopsea extraction composition of crease-resistant effect, so that the black ginseng cosmetics of preparing not only do not contain for the harmful composition of skin, can discharge toxin on the contrary, eliminate abscess, smooth spot, the prevention melanotic nevus, the desalination mottle, thereby improve skin quality, the even colour of skin, eliminate flaw, skin whitening, can concentrate moisture and the nutrition that provides sufficient for skin simultaneously, moisturizing, lock water, moisturizing, keep the water oil poised state of skin the best, particularly also has significant antioxidation, eliminating wrinkle, anti-aging effect, aforementioned combined factors effect, thereby recover elasticity and the gloss of skin, skin is inculcated healthy anger and vigor, skin is got back to and kept young attitude.
Further specify technical scheme of the present invention below in conjunction with accompanying drawing and by the specific embodiment; but following example only is simple and easy example of the present invention; do not represent or limit the scope of the present invention, interest field of the present invention is as the criterion with claims.
Description of drawings
Fig. 1 is that koryo insam steams the appearance color variation diagram that steams each time in the solarization process after shining for 9 times.
Fig. 2 is the black comparison diagram that participates in ginsenoside's component content in the Radix Ginseng Rubra.
Fig. 3 is ginsenoside Rg3's chemical structural formula.
Fig. 4 is that the black conopsea extraction of variable concentrations in the test example 1 is for the inhibition comparison diagram of collagen hydrolysate enzyme (MMP-1) activity.
Fig. 5 is that the moisture-retaining capacity that prolongs in time of black conopsea extraction, 1,3 butylene glycol, water in the test example 2 changes comparison diagram.
Fig. 6 is that the experimenter uses the near the eyes variation comparison diagram of skin conditions of black ginseng cosmetics front and back in the test example 3.
The specific embodiment
For the present invention is described better, be convenient to understand technical scheme of the present invention, typical but non-limiting embodiment of the present invention is as follows:
Embodiment 1:
Deceive conopsea extraction according to following technique preparation:
1. gather the koryo insam that trophophase reaches 6 years, clean up;
2. steam for the first time and shine: under 60 ℃ temperature, the koryo insam after 1. step cleaned cooks 2.5h, then dry 108h under 30 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
4. with step (1) 3. nine to steam the concentration that nine tanned ginsengs join 20 times of its quality be in the 1,3 butylene glycol of 30wt%, remove by filter impurity after fully reacting 1.5h;
5. repeating step operation 1. is 3 times;
6. vacuum concentration step product 2. under 50 ℃ the temperature, the concentration that adds 30 times of its quality is that the ethanol of 70wt% dilutes;
7. the antiseptic that adds its quality 1wt% in the product that 6. obtains to step, the described antiseptic compositions that to be hexanediol, Flos Magnoliae glycol, tropolone consist of according to the mass ratio of 1:1:1.
Embodiment 2:
Deceive conopsea extraction according to following technique preparation:
1. gather the koryo insam that trophophase reaches 4 years, clean up;
2. steam for the first time and shine: under 50 ℃ temperature, the koryo insam after 1. step cleaned cooks 3.5h, then dry 140h under 20 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
4. with step (1) 3. nine to steam the concentration that nine tanned ginsengs join 30 times of its quality be in the 1,3 butylene glycol of 35wt%, remove by filter impurity after fully reacting 0.5h;
5. repeating step operation 1. is 2 times;
6. vacuum concentration step product 2. under 60 ℃ the temperature, the concentration that adds 40 times of its quality is that the ethanol of 70wt% dilutes;
7. the antiseptic hexanediol that adds its quality 0.5wt% in the step product 6..
Embodiment 3:
Deceive conopsea extraction according to following technique preparation:
1. gather the koryo insam that trophophase reaches 5 years, clean up;
2. steam for the first time and shine: under 70 ℃ temperature, the koryo insam after 1. step cleaned cooks 1.5h, then dry 70h under 40 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
4. with step (1) 3. nine to steam the concentration that nine tanned ginsengs join 10 times of its quality be in the 1,3 butylene glycol of 20wt%, remove by filter impurity after fully reacting 3h;
5. repeating step operation 1. is 5 times;
6. vacuum concentration step product 2. under 40 ℃ the temperature, the concentration that adds 20 times of its quality is that the ethanol of 70wt% dilutes;
7. the antiseptic Flos Magnoliae glycol that adds its quality 2wt% in the step product 6..
Embodiment 4:
Deceive conopsea extraction according to following technique preparation:
1. gather koryo insam, clean up;
2. steam for the first time and shine: under 65 ℃ temperature, the koryo insam after 1. step cleaned cooks 2h, then dry 90h under 35 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
4. with step (1) 3. nine to steam the concentration that nine tanned ginsengs join 25 times of its quality be in the 1,3 butylene glycol of 40wt%, remove by filter impurity after fully reacting 1h;
5. repeating step operation 1. is 4 times;
6. vacuum concentration step product 2. under 45 ℃ the temperature, the concentration that adds 25 times of its quality is that the ethanol of 70wt% dilutes;
7. the antiseptic tropolone that adds its quality 0.2wt% in the step product 6..
Embodiment 5:
Deceive conopsea extraction according to following technique preparation:
1. gather the koryo insam that trophophase reaches 6 years, clean up;
2. steam for the first time and shine: under 55 ℃ temperature, the koryo insam after 1. step cleaned cooks 3h, then dry 120h under 25 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
4. with step (1) 3. nine to steam the concentration that nine tanned ginsengs join 25 times of its quality be in the 1,3 butylene glycol of 25wt%, remove by filter impurity after fully reacting 2h;
5. repeating step operation 1. is 3 times
6. vacuum concentration step product 2. under 55 ℃ the temperature, the concentration that adds 35 times of its quality is that the ethanol of 70wt% dilutes;
7. the antiseptic that adds its quality 1.5wt% in the product that 6. obtains to step, the described antiseptic compositions that to be hexanediol, Flos Magnoliae glycol, tropolone consist of according to the mass ratio of 1:1:1.
Embodiment 6:
A kind of black ginseng cosmetics are made of the raw material components of following mass percent (wt%):
The black conopsea extraction of 10wt% embodiment 1; 8wt% glyceryl alcohol 26; the 5wt% butanediol; 5wt% glycerol; 4wt% Bo Niao Suan Na; 2wt% nicotine amine; the 1wt% sea water; the 1wt% isostearyl glyceryl pentaerythrityl ether; the 0.525wt% ethohexadiol; 0.22wt% 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers; the 0.2wt%PEG-60 castor oil hydrogenated; the 0.175wt% glycerol caprylate; the 0.15wt%PEG-40 castor oil hydrogenated; 0.15wt%PPG-26-butylol polyether-26; the 0.14wt% carbomer; the 0.14wt% triethanolamine; 0.1wt% Herba Portulacae extract; 0.055wt% prickly-pear cactus extract; 0.05wt% perfume; the 0.05wt% UVNUL MS-40; the 0.05wt% xanthan gum; 0.045wt% Fructus Hordei Germinatus extract; the 0.04wt% adenosine; 0.02wt% caramel; 0.01wt% ethylenediamine tetraacetic ethyl disodium; the 0.01wt% hydroxypropyl cyclodextrin; 0.01wt% Chinese juniper xylem extract; all the other are water.
Test example 1:
The black conopsea extraction of test implementation example 1 is for the active inhibition of collagen hydrolysate enzyme (MMP-1):
Test method:
The black conopsea extraction of embodiment 1 is diluted to respectively 0.001g/ml, 0.0025g/ml, 0.005g/ml, 0.01g/ml, five Concentraton gradient of 0.025g/ml, respectively get concentration that 5ml joins respectively 100ml and be in the aqueous solution of collagen hydrolysate enzyme (MMP-1) of 10wt%, observe the black conopsea extraction of variable concentrations for the impact of collagen hydrolysate enzymatic activity.
Result of the test:
As shown in Figure 4, wherein the concentration (g/ml) of conopsea extraction is deceived in the abscissa representative, and the activity that vertical coordinate represents the collagen hydrolysate enzyme suppresses degree.As can be seen from the figure, black conopsea extraction is proportionate for the inhibition of collagen hydrolysate enzymatic activity and the concentration of himself, concentration more Gao Ze is stronger for the inhibition of collagen hydrolysate enzymatic activity, when the concentration of black conopsea extraction is 0.025g/ml, the activity inhibited of 50% collagen hydrolysate enzyme is arranged.As seen the activity that black conopsea extraction can establishment collagen hydrolysate enzyme, thus the protection collagen protein is kept skin elasticity.
Test example 2:
The moistening effect of the black conopsea extraction of test implementation example 1:
Test method:
Get black conopsea extraction, 1,3 butylene glycol, the water equivalent of embodiment 1, the moisture-retaining capacity of observing respectively the three.
Result of the test:
As shown in Figure 5, wherein abscissa represents the time, and vertical coordinate represents moisture-retaining capacity (take initial moisture-retaining capacity as 100%).As can be seen from the figure, prolongation three's in time moisture-retaining capacity is all descending, and is the fastest but the moisture-retaining capacity of water descends, and the moisture-retaining capacity of black conopsea extraction descends the slowest; The moisture-retaining capacity of water drops to 0 behind the 24h, and that the moisture-retaining capacity of black conopsea extraction drops to is initial 20%, and the moisture-retaining capacity of black conopsea extraction is the highest in the three behind the 24h.As seen black conopsea extraction has good moisturizing, lock water effect, can increase skin vitality, slow down aging.
Test example 3:
The anti-wrinkle effect of the black ginseng cosmetics of test implementation example 6:
Test method:
The black ginseng cosmetics of getting embodiment 6 are applied near the eyes skin of experimenter, and each 0.2ml, observed the near the eyes situation of change of skin of experimenter in 7 days afterwards at every day 2 times.
Result of the test:
As shown in Figure 6, wherein [picture 1] for the experimenter use before and after the contrast photo of skin near the eyes, [picture 2] be [picture 1] by duplicating gained picture after edition image analysing computer.As can be seen from the figure, used after the black ginseng cosmetics, the experimenter near the eyes situation of skin has obtained obvious improvement, and mottle desalination, skin quality water profit, the colour of skin is even, wrinkle is thin out and elasticity and the gloss enhancing of minimizing, skin.As seen black ginseng cosmetics have significant light speckle, moisturizing, crease-resistant, white-skinned face function, make skin return young attitude.
Should be noted that and understand, in the situation that does not break away from the desired the spirit and scope of the present invention of accompanying claim, can make to the present invention of foregoing detailed description various modifications and improvement.Therefore, the scope of claimed technical scheme is not subjected to the restriction of given any specific exemplary teachings.
Applicant's statement, the present invention illustrates proportioning raw materials of the present invention and preparation process by above-described embodiment, but the present invention is not limited to said ratio and preparation process, does not mean that namely the present invention must rely on above-mentioned preparation process and could implement.The person of ordinary skill in the field should understand, any improvement in the present invention to the interpolation of the equivalence replacement of the selected raw material of the present invention and auxiliary element, the selection of concrete mode etc., all drops within protection scope of the present invention and the open scope.
Claims (10)
1. the treatment process of a black ginseng is characterized in that, comprises following processing step:
(1) nine steams the processing of nine tanned ginsengs:
1. gather koryo insam, clean up;
2. steam for the first time and shine: under 50 ℃-70 ℃ temperature, the koryo insam after 1. step cleaned cooks 1.5-3.5h, then dry 70-140h under 20 ℃-40 ℃ temperature;
3. repeating step operation 2. is 8 times, finishes and steams for the second time the process that solarization-Di steams solarization for nine times, obtains nine and steams nine tanned ginsengs;
(2) acquisition of black conopsea extraction:
1. with step (1) nine steaming nine tanned ginsengs to join its quality 10-30 concentration doubly be in the 1,3 butylene glycol of 20wt%-40wt% 3., remove by filter impurity after fully reacting 0.5-3h;
2. repeating step operation 1. is 2-5 time;
3. vacuum concentration step product 2. under 40 ℃-60 ℃ the temperature, the ethanol that adds its quality 20-40 concentration doubly and be 70wt% dilutes;
4. the antiseptic that adds its quality 0.2wt%-2wt% in the step product 3..
2. treatment process according to claim 1 is characterized in that, described step (1) 1. described in koryo insam be the koryo insam that trophophase reaches 4-6; Be preferably the koryo insam that trophophase reaches 6 years.
3. treatment process according to claim 1 and 2 is characterized in that, described step (1) 2. in, the described temperature that cooks is 55 ℃-65 ℃; Be preferably 60 ℃;
Preferably, the described time that cooks is 2-3h; Be preferably 2.5h;
Preferably, the temperature of described drying is 25 ℃-35 ℃; Be preferably 30 ℃;
Preferably, the time of described drying is 90-120h; Be preferably 108h.
4. one of according to claim 1-3 described treatment process is characterized in that, described step (2) 1. in, the quality of 1,3 butylene glycol is nine to steam nine 15-25 that shine quality doubly; Be preferably 20 times;
Preferably, the concentration of described 1,3 butylene glycol is 25wt%-35wt%; Be preferably 30wt%.
5. one of according to claim 1-4 described treatment process is characterized in that, described step (2) 2. in, the number of times of described repetitive operation is 3-4 time; Be preferably 3 times.
6. one of according to claim 1-5 described treatment process is characterized in that, described step (2) 3. in, described temperature is 45-55 ℃; Be preferably 50 ℃;
Preferably, the addition of the ethanol of described 70wt% is 25-35 times; Be preferably 30 times.
7. one of according to claim 1-6 described treatment process is characterized in that, described step (2) 4. in, the addition of described antiseptic is the 0.5wt%-1.5wt% of extract quality; Be preferably 1wt%.
8. one of according to claim 1-7 described treatment process is characterized in that, described step (2) 4. in, the select oneself combination of any one or at least two kinds in glycol, Flos Magnoliae glycol, the tropolone of described antiseptic.
9. the preparation technology of black ginseng cosmetics is characterized in that, adding content in preparation process is the black conopsea extraction of the claim 1-8 acquisition of 1wt%-20wt%.
10. preparation technology according to claim 9 is characterized in that, the addition of described black conopsea extraction is 3wt%-15wt%; Be preferably 5wt%-10wt%.
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| CN113116778A (en) * | 2021-04-16 | 2021-07-16 | 广州中草世家化妆品有限公司 | Ginseng extracting solution and preparation method and application thereof |
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