CN102872314B - Drug for treating gout and preparation method for drug - Google Patents

Drug for treating gout and preparation method for drug Download PDF

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Publication number
CN102872314B
CN102872314B CN201210416621.9A CN201210416621A CN102872314B CN 102872314 B CN102872314 B CN 102872314B CN 201210416621 A CN201210416621 A CN 201210416621A CN 102872314 B CN102872314 B CN 102872314B
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gram
grams
radix
fructus
gout
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CN201210416621.9A
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CN102872314A (en
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牛健坤
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牛健坤
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Abstract

The invention discloses a drug for treating gout and a preparation method for the drug. The drug for treating the gout is mainly prepared from the following traditional Chinese medicines in a certain weight ratio: frankincense, liquorice, pawpaw, monkshood, ephedra, fructus forsythia, Red Paeony Root, radix achyranthis bidentatae, Angelica sinensis, rhizoma anemarrhenae, jasmine, radix paeoniae alba, rhizoma alismatis, radix sophorae flavescentis, radix aconiti sinensis and the like. The drug for treating the gout has functions of clearing internal heat due to yin deficiency and hectic fever due to yin deficiency and dispelling wind and removing obstruction in the meridians, is fast in effect when being used for treating the gout, and is low in cost, short in course of treatment and high in cure rate.

Description

A kind of medicine for the treatment of gout and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of gout and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Gout claims again " hyperuricemia ", and purine metabolism obstacle, belongs to arthritis a kind of.Gout is that the metabolism of the material of purine in human body gets muddled, and the synthetic increase of uric acid or discharge reduce, and cause hyperuricemia, when serum Uric Acid Concentration is too high, uric acid is deposited in joint, cartilage and kidney with the form of sodium salt, causes and organizes foreign body inflammatory reaction, i.e. gout.At present gout treatment be mainly according to clinical symptoms for administration, be mainly in stage of attack, to eat colchicine to add analgesic so that antiinflammatory fast, remove painfully, the intermission eats the medicines such as other purine and reduces uric acid, prevention is outbreak again.Substantially, gout Western medicine used all has serious side effect at present, and cures the symptoms, not the disease.In the intermission, take uric acid resisting Western medicine in addition, not only drug withdrawal bounce-back is very fast, and often because uric acid dissolving is too fast, causes the outbreak of transitivity gout.The most fearful, have Western medicine for a long time, be doomed to eat bad Liver and kidney spleen, cause the gout that cannot reverse repeatedly to aggravate outbreak.This is also that a lot of ward mates would rather bear the reason that severe pain also be unwilling to have Western medicine.Gout has affected daily study, work and life, to patient, brings greatly body and mind misery.Therefore there is great demand to the Chinese medicine of effective treatment gout in people.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment gout, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can treat gout.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects Olibanum, Radix Glycyrrhizae, Fructus Chaenomelis, Radix Aconiti Lateralis Preparata, Herba Ephedrae, Fructus Forsythiae, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Fructus Gardeniae, the Radix Paeoniae Alba, Rhizoma Alismatis, Radix Sophorae Flavescentis, Radix Aconiti, Cortex Phellodendri, Cortex Moutan, Rhizoma Cimicifugae, Fructus Liquidambaris, Herba Violae, Flos Carthami, Squama Manis, Radix Clematidis, Semen Plantaginis, Lumbricus, Radix Rehmanniae, Herba Asari, Semen Vaccariae and Myrrha to combine, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can fast treating gout.Wherein select Olibanum to be because its nature and flavor are arduous, temperature, enters the heart, liver, spleen channel, has regulating qi and activating blood, and analgesic therapy chases after malicious function, controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, processs use, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus , Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, and ulcer sores, separates poison of drug and alimentary toxicosis.Select Fructus Chaenomelis to be because its nature and flavor are sour, temperature, enters liver, spleen channel, has suppressing the hyperactive liver and easing the stomach, and the function of the relaxing muscles and tendons that dries being controlled the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.Selecting Radix Aconiti Lateralis Preparata is because of its property acrid-sweet flavor, and heat is poisonous, enter the heart, spleen, kidney channel, have recuperating depleted YANG to mend fire, the function of dispelling cold and removing dampness, control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted contrary, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, the contracture of anemofrigid-damp arthralgia , Wei lame, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.Select Herba Ephedrae to be because its nature and flavor are arduous, temperature, enters lung, urinary bladder channel, has diaphoresis, relievings asthma, the function of diuretic, the cold table that cures the wound is real, and fever with chills is lossless, headache is had a stuffy nose, arthralgia, cough and asthma, edema due to wind pathogen edema; dysuria, ailment said due to cold or exposure insensitive impediment, munbness, rubella pruritus.Select Fructus Forsythiae to be because its nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, controls warm poison and goes mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , Epilepsy abdominal mass stomachache, injury from falling down, carbuncle skin infection.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and subduing inflammation, controls gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe in invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm enters the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturizing laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select the Rhizoma Anemarrhenae to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, there is nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, there is heat clearing away, pathogenic fire purging, the function of removing heat from blood, controls calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Rhizoma Alismatis to be because its nature and flavor are sweet, cold, enter urinary bladder channel, there is diuretic, eliminating dampness by diuresis, the function expelling the heat-evil, controls dysuria, and edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Select Radix Sophorae Flavescentis to be because its nature and flavor are bitter, cold, enter liver, kidney, large intestine, small intestine meridian, there is heat clearing away, dampness, the function of parasite killing, controls toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, erosion of vulva pruritus due to damp pathogen, scrofula, scalds.Select Radix Aconiti, its nature and flavor are pungent, and heat is poisonous, enter spleen, the gate of vitality's two warps, have dispelling cold and dampness, loose ailment said due to cold or exposure, and warming the meridian, the function of pain relieving, controls anemofrigid-damp arthralgia, severe and migratory arthralgia pain, spasm of the limbs, hemiplegia, wind syndrome of head headache, trusted subordinate's cold type of pain, carbuncle of yin nature toxic swelling.Select Cortex Phellodendri to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, there is nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Cortex Moutan to be because its nature and flavor are arduous, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, sends out speckle , Jing Epilepsy, and tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Rhizoma Cimicifugae to be because the sweet pungent micro-hardship of its nature and flavor is cool, enter lung, spleen, stomach warp, have yang invigorating, deliver rash, the function of removing toxic substances, controls seasonal epidemic pathogens epidemic disease labor, headache cold and heat, and laryngalgia, aphtha scar, macule is not saturating, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women's metrorrhagia and leukorrhagia, uterus tenesmus, carbuncle sore tumefacting virus.Select Fructus Liquidambaris to be because its nature and flavor are bitter flat, current 12 warps, have dispelling wind and removing obstruction in the collateral, and the function of promoting urination to remove dampness, harnesses the river swollen, distension, and amenorrhea, breast is few, contracture of the limbs.Selecting Herba Violae is that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because of its nature and flavor bitter, acrid, cold, and the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Select Flos Carthami to be because its nature and flavor are pungent, temperature, enters the heart, Liver Channel, has promoting blood circulation to restore menstrual flow, and the function of blood stasis removing pain relieving is controlled amenorrhea , mass in the abdomen, difficult labour, and stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Squama Manis to be because its nature and flavor are salty, cool, enter liver, stomach warp, have the routed carbuncle of detumescence, search wind active, the function of the stimulating milk secretion of stimulating the menstrual flow, controls carbuncle skin ulcer swollen, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external hemostasis.Select Radix Clematidis to be because its nature and flavor are pungent salty, temperature, poisonous, enter urinary bladder channel, there is wind-damp dispelling, the meridian dredging, expectorant saliva, the function of the loose hypochondriac lump, controls gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria , lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.Select Semen Plantaginis to be because its nature and flavor are sweet, cold, enter kidney, urinary bladder channel, there is diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Select Lumbricus to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, there is heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control height fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid, controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, sends out speckle dermexanthesis.Select Herba Asari to be because its nature and flavor are pungent, temperature, enters lung, kidney channel, dispel the wind, and cold expelling, row water, opens the function of stealing, and controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Semen Vaccariae to be because its nature and flavor are bitter flat, enter liver, stomach warp, have promoting the circulation of blood to stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, the function of detumescence sore, controls women's amenorrhea, galactostasis, and difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.Select Myrrha to be because its nature and flavor are bitter, flat, enter Liver Channel, there is loose blood blood stasis removing, the function of subduing swelling and relieving pain, controls and falls damage, incised wound, muscles and bones, all Tong , of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Olibanum 10-25 gram of Radix Glycyrrhizae 4-12 gram of Fructus Chaenomelis 8-18 gram
Radix Aconiti Lateralis Preparata 8-12 gram of Herba Ephedrae 2-8 gram of Fructus Forsythiae 15-28 gram
Radix Paeoniae Rubra 10-22 gram of Radix Achyranthis Bidentatae 8-20 gram of Radix Angelicae Sinensis 10-20 gram
Rhizoma Anemarrhenae 10-20 gram of Fructus Gardeniae 5-12 gram of Radix Paeoniae Alba 5-18 gram
Rhizoma Alismatis 10-25 gram of Radix Sophorae Flavescentis 10-22 gram of Radix Aconiti 12-22 gram
Cortex Phellodendri 8-20 gram of Cortex Moutan 14-22 gram liter fiber crops 4-12 gram
Fructus Liquidambaris 8-18 gram of Herba Violae 10-22 gram of Flos Carthami 6-12 gram
Squama Manis 10-20 gram of Radix Clematidis 10-30 gram of Semen Plantaginis 10-20 gram
Lumbricus 10-20 gram of Radix Rehmanniae 10-20 gram of Herba Asari 8-12 gram
Semen Vaccariae 20-40 gram of Myrrha 8-22 gram
Wherein, be preferably
12 grams of 8 grams of Fructus Chaenomeliss of 15 grams of Radix Glycyrrhizaes of Olibanum
20 grams of 5 grams of Fructus Forsythiaes of 10 grams of Herba Ephedraes of Radix Aconiti Lateralis Preparata
15 grams of 10 grams of Radix Angelicae Sinensis of 15 grams of Radix Achyranthis Bidentataes of Radix Paeoniae Rubra
10 grams of 10 grams of Radix Paeoniae Albas of 20 grams of Fructus Gardeniaes of the Rhizoma Anemarrhenae
20 grams of 15 grams of Radix Aconitis of 20 grams of Radix Sophorae Flavescentiss of Rhizoma Alismatis
8 grams of 10 grams of Cortex Moutans of Cortex Phellodendri, 20 gram liter fiber crops
8 grams, 12 grams of Flos Carthamis of 12 grams of Herba Violaes of Fructus Liquidambaris
15 grams of 25 grams of Semen Plantaginiss of 15 grams of Radix Clematidis of Squama Manis
10 grams of 14 grams of Herba Asaris of 12 grams of Radix Rehmanniae of Lumbricus
12 grams of 30 grams of Myrrhas of Semen Vaccariae
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Olibanum: choose the sub-impurity of shakeout;
2, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
3, Fructus Chaenomelis: clear water is cleaned, slightly soaks, and moistening, to thoroughly, is put in food steamer and cooked, and takes advantage of fervent sheet, and weather exposure, take by the red atropurpureus that turns as degree;
4, Radix Aconiti Lateralis Preparata: be soaked in water, pull out, section, dries;
5, Herba Ephedrae: choose decontamination, remove most woody stems and undesirable root, wash, cutting after micro-profit, dry;
6, Fructus Forsythiae: choose clean impurity, stranding is opened, except discarding stalk;
7, Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping, cleans, runs through, shave, and dry, sieve removes chip;
8, Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
9, Radix Angelicae Sinensis: choose decontamination, clean, moistening, slightly dries in the air when suitable to inside and outside humidity, and section is dried;
10, the Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, softens, and section is dried;
11, Fructus Gardeniae: sieve dedust bits, choose decontamination, pulverize and sieve or cut off two ends;
12, the Radix Paeoniae Alba: choose decontamination, size separately, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
13, Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;
14, Radix Sophorae Flavescentis: choose clean impurity, remove residual stem, clean earth, be soaked in water, pull out, run through, section, dries;
15, Radix Aconiti: choose decontamination, clean ash bits, dry;
16, Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding, dry;
17, Cortex Moutan: choose decontamination, remove core, clean, run through, section, dries;
18, Rhizoma Cimicifugae: choose decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
19, Fructus Liquidambaris: remove impurity, clean, dry;
20, Herba Violae: get crude drug, remove impurity, clean, slightly dry in the air, cutting, dry;
21, Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
22, Squama Manis: get the Squama Manis sheet of choosing clean, separately size, separately puts sand in pot and fry to easily, adds Squama Manis sheet, fries to heaving while being golden yellow, takes out, and sieve shakeout, cools;
23, Radix Clematidis: choose clean impurity, remove residual stem, be soaked in water, pull out and run through, cutting, dries;
24, Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
25, Lumbricus: choose decontamination, water rinses, and pulls out in time, dries cutting;
26, Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
27, Herba Asari: Ex-all impurity, water spray profit, cutting in time, dries;
28, Semen Vaccariae: the clean impurity of winnowing with a dustpan, put in pot, while spending six, seventy percent with slow fire stir-fry in vain to popping, take out, cool;
29, Myrrha: choose decontamination, break into fragment.
Two, preparation
1, the Olibanum of described weight, Radix Glycyrrhizae, Fructus Chaenomelis, Radix Aconiti Lateralis Preparata, Herba Ephedrae, Fructus Forsythiae, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Fructus Gardeniae, the Radix Paeoniae Alba, Rhizoma Alismatis, Radix Sophorae Flavescentis, Radix Aconiti, Cortex Phellodendri, Cortex Moutan, Rhizoma Cimicifugae, Fructus Liquidambaris, Herba Violae, Flos Carthami, Squama Manis, Radix Clematidis, Semen Plantaginis, Lumbricus, Radix Rehmanniae, Herba Asari, Semen Vaccariae, Myrrha are added to 6 times of water gagings, soak 60 minutes, intense fire decocts boiling 20 minutes, use again slow fire boiling 15 minutes, filter and obtain decoction liquor for the first time.
2, the medicinal residues of filtration are added to 3 times of amounts of water, intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time.
3, twice decoction liquor merged, intense fire boils, then uses slow fire boiling 10 minutes, must take medicinal liquid, will take medicinal liquid and be divided into 4 doses.
Medicine of the present invention has treatment yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and the function of dispelling wind and removing obstruction in the collateral, is used for the treatment of gout instant effect, and short treating period, does not recur, and cure rate is high.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day twice, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 150 examples for medical treatment.
2, diagnostic criteria
Gout can be divided into four-stage clinically: the first stage is the metabolic arthritis disease phase, and patient, except blood uric acid raises, does not occur the clinical symptoms of gout; Second stage is that gout is early stage, and blood uric acid persistence increases, and causes acute gouty arthritis to break out, and starting position is often the halluces of foot, redness and swelling of joints, scorching hot swelling; Phase III is gout mid-term, a toe joint when just starting to fall ill, feed through to gradually the whole body joints such as finger, toe, wrist, ankle, knee joint, and then soft tissue around and sclerotin also suffer destruction and dysfunction in various degree, uric acid crystal constantly deposits, formed at leisure the same " tophus " of calculus, now, normal renal function or show as slight decline; Fourth stage is late gout, patient's joint deformity and dysfunction are day by day serious, tophus increases, volume increases, easily ulceration flows out white urate crystal, clinically occur that the prompting renal functioies such as edema, oliguria, albuminuria, nocturia increase, hypertension, anemia suffer damage, renal function obviously goes down.
3, Therapeutic Method
Select above-mentioned medicament, each 1 dose 10 days is a course for the treatment of, takes continuously 4 courses for the treatment of.Period in a medicine, note life, diet wants rule.
4, efficacy assessment standard
Effective: clinical symptom disappearance after treatment, blood uric acid is down to normally, in 1~1.5 year, has no recurrence
Take a turn for the better: clinical symptoms is obviously improved, blood uric acid declines, and the outbreak gap phase obviously extends;
Invalid: clinical partial symptoms disappears or without change, do not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy patient with gout 150 examples of the present invention, effective 145 examples of result, obvious effective rate is 96.67%, 3 examples that take a turn for the better, and improvement rate is 2%, invalid 2 examples, total effective rate is 98.67%.

Claims (2)

1. a medicine for the treatment of gout, is characterized in that: it is to be made by the crude drug within the scope of following weight:
Olibanum 10-25 gram of Radix Glycyrrhizae 4-12 gram of Fructus Chaenomelis 8-18 gram
Radix Aconiti Lateralis Preparata 8-12 gram of Herba Ephedrae 2-8 gram of Fructus Forsythiae 15-28 gram
Radix Paeoniae Rubra 10-22 gram of Radix Achyranthis Bidentatae 8-20 gram of Radix Angelicae Sinensis 10-20 gram
Rhizoma Anemarrhenae 10-20 gram of Fructus Gardeniae 5-12 gram of Radix Paeoniae Alba 5-18 gram
Rhizoma Alismatis 10-25 gram of Radix Sophorae Flavescentis 10-22 gram of Radix Aconiti 12-22 gram
Cortex Phellodendri 8-20 gram of Cortex Moutan 14-22 gram liter fiber crops 4-12 gram
Fructus Liquidambaris 8-18 gram of Herba Violae 10-22 gram of Flos Carthami 6-12 gram
Squama Manis 10-20 gram of Radix Clematidis 10-30 gram of Semen Plantaginis 10-20 gram
Lumbricus 10-20 gram of Radix Rehmanniae 10-20 gram of Herba Asari 8-12 gram
Semen Vaccariae 20-40 gram of Myrrha 8-22 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
12 grams of 8 grams of Fructus Chaenomeliss of 15 grams of Radix Glycyrrhizaes of Olibanum
20 grams of 5 grams of Fructus Forsythiaes of 10 grams of Herba Ephedraes of Radix Aconiti Lateralis Preparata
15 grams of 10 grams of Radix Angelicae Sinensis of 15 grams of Radix Achyranthis Bidentataes of Radix Paeoniae Rubra
10 grams of 10 grams of Radix Paeoniae Albas of 20 grams of Fructus Gardeniaes of the Rhizoma Anemarrhenae
20 grams of 15 grams of Radix Aconitis of 20 grams of Radix Sophorae Flavescentiss of Rhizoma Alismatis
8 grams of 10 grams of Cortex Moutans of Cortex Phellodendri, 20 gram liter fiber crops
8 grams, 12 grams of Flos Carthamis of 12 grams of Herba Violaes of Fructus Liquidambaris
15 grams of 25 grams of Semen Plantaginiss of 15 grams of Radix Clematidis of Squama Manis
10 grams of 14 grams of Herba Asaris of 12 grams of Radix Rehmanniae of Lumbricus
12 grams of 30 grams of Myrrhas of Semen Vaccariae.
CN201210416621.9A 2012-10-28 2012-10-28 Drug for treating gout and preparation method for drug CN102872314B (en)

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Publication number Priority date Publication date Assignee Title
CN103263655A (en) * 2013-06-03 2013-08-28 石欣 Chinese medicine composition for treating gouty arthritis
CN103735671B (en) * 2013-12-27 2016-01-27 南宁市品迪生物工程有限公司 A kind of medicine for the treatment of gout
CN104208307A (en) * 2014-08-18 2014-12-17 赖彧 Chinese patent medicine treating gout
CN104398608A (en) * 2014-12-01 2015-03-11 高德龙 Deer sinew gout healthcare wine
CN105434952A (en) * 2015-12-29 2016-03-30 余勇 Medicine for treating scarlatina and preparation method thereof
CN105435187A (en) * 2015-12-29 2016-03-30 余勇 Medicine for treating xerosis and preparation method thereof

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CN1375298A (en) * 2001-01-04 2002-10-23 黄兆元 Pain-relieving notoginseng mixture
CN1401346A (en) * 2001-08-23 2003-03-12 邢良国 Numbness- and pain-eliminating capsule and preparing method thereof
CN1457820A (en) * 2002-05-14 2003-11-26 常顶峰 Pill for eliminating stagnation and pains
CN101732588A (en) * 2010-01-18 2010-06-16 李英明 Formula of Chinese medicament for treating bodily pain syndrome

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Publication number Priority date Publication date Assignee Title
CN1375298A (en) * 2001-01-04 2002-10-23 黄兆元 Pain-relieving notoginseng mixture
CN1401346A (en) * 2001-08-23 2003-03-12 邢良国 Numbness- and pain-eliminating capsule and preparing method thereof
CN1457820A (en) * 2002-05-14 2003-11-26 常顶峰 Pill for eliminating stagnation and pains
CN101732588A (en) * 2010-01-18 2010-06-16 李英明 Formula of Chinese medicament for treating bodily pain syndrome

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