CN104436124A - Medicine for treating appendicitis and preparation method thereof - Google Patents
Medicine for treating appendicitis and preparation method thereof Download PDFInfo
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- CN104436124A CN104436124A CN201410679525.2A CN201410679525A CN104436124A CN 104436124 A CN104436124 A CN 104436124A CN 201410679525 A CN201410679525 A CN 201410679525A CN 104436124 A CN104436124 A CN 104436124A
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Abstract
The invention discloses a medicine for treating appendicitis and a preparation method thereof. The medicine is mainly prepared from the following ingredients according to a certain weight proportion: chrysanthemum, patrinia scaniosaefolia, cortex lycii radicis, safflower carthamus, dandelion, coix seed, honeysuckle, radix scutellariae, angelica, spreading hedyotis herb, and rhizoma drynariae. The medicine disclosed by the invention has the effects of clearing away heat and toxic materials, cooling blood to subside swell, removing heat and relieving pain, can be applied to treat the appendicitis with quick effect and good curative effect; the appendicitis cannot be recurred after treatment.
Description
Technical field
The present invention relates to one and treat typhlitic medicine and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Appendicitis refers to the Abdominal Surgery that vermiform appendix changes due to many factors formation inflammatory.It is a kind of commonly encountered diseases.Early stage diagnosis and treatment, patient is many can rehabilitation in a short time, if delay diagnosis and treatment can cause serious complication, even causes death, and mortality rate is 0.1% one 0.2%.Often there are the performances such as the rising of right lower abdomen pain, body temperature, vomiting and neutrophilic leukocytosis clinically.Appendicitis is surgical common disease, and the most common with youth, male is more than women.Acute appendicitis is comparatively common clinically, and each age group and pregnancy women all can be fallen ill, and chronic appendicitis is comparatively rare.At present, because Western medicine effectively cannot treat appendicitis, and long-term taking Western medicine has more side effect, therefore, and the demand that people are very large to effectively treatment typhlitic Chinese medicine existence.
Summary of the invention
The present inventor, through research repeatedly and clinical test repeatedly and checking, finally have found the effectively typhlitic medicine for the treatment of, thus completes the present invention.
Object of the present invention is just to provide one can effectively treat typhlitic composition of medicine.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Flos Chrysanthemi Indici, Herba Patriniae, Cortex Lycii, Flos Carthami, Herba Taraxaci, Semen Coicis, Flos Lonicerae, Radix Scutellariae, Radix Angelicae Sinensis, Herba Hedyotidis Diffusae, Rhizoma Drynariae, Herba Violae, Radix Cirsii Japonici, Radix Et Rhizoma Rhei, Radix Bupleuri, Radix Trichosanthis, Caulis Sargentodoxae, Fructus Forsythiae, Semen Benincasae, Semen Persicae, Rhizoma Acori Graminei, Cortex Magnoliae Officinalis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Caulis Lonicerae, Rhizoma Zingiberis Recens, Herba Taxilli, Pericarpium Citri Reticulatae, Semen Pruni, Fructus Aurantii, Rhizoma Imperatae, Herba Andrographis medicine to combine, each efficacy of drugs is made by these drug regimens to produce synergism, thus can the typhlitic recurrence of fast treating.Flos Chrysanthemi Indici is wherein selected to be that cool, enter lung, Liver Channel, have wind and heat dispersing, the function of subduing swelling and detoxicating, controls anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, furuncle, carbuncle, aphtha, erysipelas, eczema, epidemic blisters because its nature and flavor toil.Herba Patriniae is selected to be because its nature and flavor are pungent, bitter, cool.Return stomach, large intestine, Liver Channel.Heat-clearing and toxic substances removing, removing blood stasis and expelling pus.For appendicitis, dysentery, enteritis, hepatitis, eye conjunctivitis, postnatal blood stasis is suffered from abdominal pain, carbuncle furuncle.Optionally Cortex Lycii is because its nature and flavor are sweet, cold, and enter lung, liver, kidney channel, have heat clearing away, the function of removing heat from blood, control asthenia hectic fever night sweat, lung-heat cough with asthma, spit blood, epistaxis, stranguria with blood, quenches one's thirst, hypertension, carbuncle, malignant boil.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea ， mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Semen Coicis is selected to be that cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea because its property slightly sweet flavor.Flos Lonicerae is selected to be because its nature and flavor are sweet, cold, enter lung, stomach warp, have heat clearing away, the function of removing toxic substances, control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Radix Scutellariae is selected to be because its nature and flavor are bitter, cold, enter the heart, lung, gallbladder, large intestine channel, have removing the relative excess fire, except damp and hot, hemostasis, antiabortive function, controls high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tells, is defeated in battle, collapses, leaks, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Herba Hedyotidis Diffusae to be because its property bitter but sweet flavor, cold, enter the heart, liver, spleen three warp, have heat clearing away, dampness removing, the function of removing toxic substances, controls dyspnea and cough due to lung-heat, tonsillitis, pharyngolaryngitis, appendicitis, dysentery, jaundice, pelvic inflammatory disease, adnexitis, carbuncle furuncle, venom.Rhizoma Drynariae is selected to be that temperature, enters liver, kidney channel, have the kidney invigorating, invigorate blood circulation, the function of hemostasis, control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus because its nature and flavor are bitter.Select Herba Violae to be that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because its nature and flavor bitter, acrid, cold, the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Select Radix Cirsii Japonici to be because its nature and flavor are sweet, cool, enter liver, spleen channel, have removing heat from blood, hemostasis, blood stasis dispelling, the function of subduing inflammation, controls haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer toxic swelling, furuncle.Radix Et Rhizoma Rhei is selected to be that enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant because its nature and flavor are bitter, cold, the function of clots absorbing blood, control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Radix Trichosanthis is selected to be that cool, enter lung, stomach warp, have and promote the production of body fluid, quench the thirst, pathogenic fire reducing, moisturize, evacuation of pus, the function of detumescence, controls calentura thirsty, quenches one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula because its nature and flavor sweetness and bitterness acid.Caulis Sargentodoxae is selected to be that flat, enter liver, large intestine two warp, relieve internal heat eliminating carbuncle, promoting blood circulation to remove obstruction in the collateral, the function of wind dispelling insecticide, controls acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition because its nature and flavor are bitter, worm pain, injury from falling down.Select Fructus Forsythiae to be because its nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Semen Benincasae is selected to be that enter meridian of Foot-JUE YIN, have lung moistening, reduce phlegm, eliminating carbuncle, the function of diuretic, controls phlegm-heat cough, lung abscess, acute appendicitis, gonorrhea, edema, beriberi, hemorrhoid, nasal surface wine Zha because its nature and flavor are sweet, cool.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Rhizoma Acori Graminei is selected to be that tepor, enters the heart, liver, spleen channel, have and have one's ideas straightened out, eliminating phlegm, regulate the flow of vital energy, invigorate blood circulation because its nature and flavor are worked hard, loose wind, the function of drying, Zhi epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Caulis Lonicerae is selected to be because its nature and flavor are sweet, cold, enter the heart, lung meridian, have heat clearing away, removing toxic substances, the function of dredging collateral, control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enter lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting, open the function of expectorant, cure cold wind and cold, vomiting, and phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Herba Taxilli to be because its property bitter but sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive function, controls soreness of waist and knee joint, and muscles and bones flaccidity is weak, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Pericarpium Citri Reticulatae is selected to be that temperature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm because its nature and flavor are bitter, pungent.Select Semen Pruni to be because its nature and flavor are worked hard sweet, flat, enter spleen, intestine and small intestine warp, have and moisturize, laxation, the therapeutic method to keep the adverse QI flowing downwards, the function of diuretic, controls QI stagnation of the large intestine, dry puckery obstructed, dysuria, extensive abdominal edema, extremity edema, beriberi.Fructus Aurantii is selected to be because its nature and flavor toil, cool.Enter lung, spleen, large intestine channel.Dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Rhizoma Imperatae to be sweet because of its nature and flavor, cold, enter lung, stomach, small intestine meridian, have removing heat from blood, hemostasis, heat clearing away, the function of diuresis, controls calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Herba Andrographis is selected to be because its nature and flavor are bitter, cold in nature, nontoxic, enter the heart, lung two warp, have heat-clearing and toxic substances removing, the function of removing heat from blood detumescence, controls acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Flos Chrysanthemi Indici 15-20 gram of Herba Patriniae 15-20 gram of Cortex Lycii 15-25 gram
Flos Carthami 8-15 gram of Herba Taraxaci 15-25 gram of Semen Coicis 25-35 gram
Flos Lonicerae 20-25 gram of Radix Scutellariae 10-15 gram of Radix Angelicae Sinensis 10-20 gram
Herba Hedyotidis Diffusae 20-30 gram of Rhizoma Drynariae 20-25 gram of Herba Violae 10-15 gram
Radix Cirsii Japonici 10-15 gram of Radix Et Rhizoma Rhei 10-20 gram of Radix Bupleuri 8-15 gram
Radix Trichosanthis 15-20 gram of Caulis Sargentodoxae 20-25 gram of Fructus Forsythiae 15-20 gram
Semen Benincasae 15-20 gram of Semen Persicae 8-15 gram of Rhizoma Acori Graminei 10-15 gram
Cortex Magnoliae Officinalis 10-20 gram of Radix Glycyrrhizae 10-20 gram of Radix Paeoniae Alba 9-15 gram
Caulis Lonicerae 15-25 gram of Rhizoma Zingiberis Recens 10-15 gram of Herba Taxilli 10-20 gram
Pericarpium Citri Reticulatae 6-10 gram of Semen Pruni 10-20 gram of Fructus Aurantii 6-12 gram
Rhizoma Imperatae 15-25 gram of Herba Andrographis 10-20 gram
Preferable amount is
Flos Chrysanthemi Indici 20 grams of Herba Patriniaes 15 grams of Cortex Lycii 20 grams
Flos Carthami 10 grams of Herba Taraxacis 20 grams of Semen Coiciss 30 grams
Flos Lonicerae 20 grams of Radix Scutellariaes 15 grams of Radix Angelicae Sinensis 15 grams
Herba Hedyotidis Diffusae 25 grams of Rhizoma Drynariae 20 grams of Herba Violaes 15 grams
Radix Cirsii Japonici 15 grams of Radix Et Rhizoma Rhei 15 grams of Radix Bupleuri 10 grams
Radix Trichosanthis 20 grams of Caulis Sargentodoxae 25 grams of Fructus Forsythiaes 18 grams
Semen Benincasae 20 grams of Semen Persicaes 10 grams of Rhizoma Acori Graminei 12 grams
Cortex Magnoliae Officinalis 15 grams of Radix Glycyrrhizaes 15 grams of Radix Paeoniae Albas 12 grams
Caulis Lonicerae 20 grams of Rhizoma Zingiberis Recenss 10 grams of Herba Taxillis 15 grams
Pericarpium Citri Reticulatae 8 grams of Semen Prunis 15 grams of Fructus Aurantiis 9 grams
Rhizoma Imperatae 20 grams of Herba Andrographis 15 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Flos Chrysanthemi Indici: remove impurity, removing undesirable root, cleans cutting, dries;
2, Herba Patriniae: get crude drug, removing impurity, with Water spray, slightly dries in the air, and cutting is dry;
3, Cortex Lycii: pick decontamination and core, slightly wash, cutting, dry;
4, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
5, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
6, Semen Coicis (parched): get and pick clean Semen Coicis and put in pot and fry to micro-yellow with slow fire, take out, cool, or with wheat bran with stir-fry also can, every Semen Coicis 100 jin, with 10 jin, wheat bran;
7, Flos Lonicerae: sieve removes silt, picks clean impurity;
8, Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and run through rear section and dry, attention is avoided tanning by the sun excessively rubescent;
9, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
10, Herba Hedyotidis Diffusae: get crude drug, removing impurity, wash quickly is clean, slightly dries in the air, cutting, dry, sieve dedust bits;
11, Rhizoma Drynariae: remove sediment contamination, cleans, slightly soaks, run through, and section, dries;
12, Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
13, Radix Cirsii Japonici: pick decontamination, clear water is cleaned, and runs through, cutting, dries;
14, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;
15, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry;
16, Radix Trichosanthis: pick decontamination, size block is separately, saturating with blister about sixty percent, pulls out, and moistening is even to inside and outside humidity, and section, dries; Or wash, pull out, shine extremely dry, be pounded fritter;
17, Caulis Sargentodoxae: be soaked in water, cleans spare, runs through, and section, dries;
18, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
19, Semen Benincasae: pick clean impurity, the used time smashs to pieces, or fry to yellow-white with slow fire, put dry place;
20, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
21, Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
22, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
23, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
24, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
25, Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;
26, Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
27, Herba Taxilli: wash, runs through, and cutting is dried;
28, Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
29, Semen Pruni: sieve removes spare, wash in a pan clean, pick clean impurity and broken shell, dry, the used time smashs to pieces;
30, Fructus Aurantii: removing flesh, core, cleans, slightly soaks, pull out, soften, and till pinching doubling with hands, section, dries;
31, Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;
32, Herba Andrographis: removing impurity, cleans, cutting, dry.
Two, prepare
1, the Flos Chrysanthemi Indici of described weight, Herba Patriniae, Cortex Lycii, Flos Carthami, Herba Taraxaci, Semen Coicis, Flos Lonicerae, Radix Scutellariae, Radix Angelicae Sinensis, Herba Hedyotidis Diffusae, Rhizoma Drynariae, Herba Violae, Radix Cirsii Japonici, Radix Et Rhizoma Rhei, Radix Bupleuri, Radix Trichosanthis, Caulis Sargentodoxae, Fructus Forsythiae, Semen Benincasae, Semen Persicae, Rhizoma Acori Graminei, Cortex Magnoliae Officinalis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Caulis Lonicerae, Rhizoma Zingiberis Recens, Herba Taxilli, Pericarpium Citri Reticulatae, Semen Pruni, Fructus Aurantii, Rhizoma Imperatae, Herba Andrographis medicine are added 8 times of water gagings and soak, soak after 90 minutes, intense fire decocts boiling 10 minutes, then within 20 minutes, filters to obtain decoction liquor for the first time with slow fire boiling.
2, add water the medicinal residues of filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, twice decoction liquor is merged, then simmer in water and namely obtain medicinal liquid in 10 minutes, be divided into by medicinal liquid 6 doses to take.
The present invention selects Caulis Sargentodoxae to be monarch drug, and Herba Hedyotidis Diffusae, Herba Violae are ministerial drug, and Fructus Forsythiae is adjuvant drug, and said medicine and all medicines, for making medicine, combine to make and treat typhlitic medicine by Radix Glycyrrhizae.
Medicine of the present invention has heat-clearing and toxic substances removing, and removing heat from blood is subsided a swelling, effect of removing obstruction for relieving pain, and treatment appendicitis instant effect, short treating period, do not recur.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient 41 example for medical treatment.
2, diagnostic criteria
(1) suffer from abdominal pain the typical acute appendicitis initial stage have middle upper abdomen or umbilicus week pain, after a few hours stomachache shift and be fixed on Right Lower Abdomen.Commitment is a kind of visceral nerve reflexive pain, therefore middle upper abdomen and the comparatively disperse of umbilicus week pain dimensions, Chang Buneng definitely locates.When inflammation involves placenta percreta and parietal peritoneum, namely pain be fixed on Right Lower Abdomen, and namely former middle upper abdomen or pain around the navel alleviate or disappear.Therefore, without typical transitivity Right Lower Abdomen history of pain can not except acute appendicitis.
Simple appendicitis is often in paroxysmal or persistence distending pain with dull pain, and persistence severe pain often prompts for suppurative or gangrenous appendicitis.Lasting severe pain involves middle lower abdomen or both sides lower abdomen, is often the sign of vermiform appendix gangrene perforation.Sometimes vermiform appendix gangrene perforation, stomachache is alleviated on the contrary to some extent, but the phenomenon of this pain relief is temporary transient, and other adjoint sings and symptomses do not improve, and aggravate even to some extent.
(2) gastrointestinal symptom of gastrointestinal symptom simple appendicitis is not given prominence to.Nausea and vomiting may be had in early days due to reflexive stomach spasm.Pelvic cavity position appendicitis or vermiform appendix gangrene perforation can have defecation frequency to increase.
(3) heating generally only has low grade fever, and without shiver with cold, suppurative appendicitis is generally also no more than 38 DEG C.High overabundant heat sees vermiform appendix gangrene, perforation or Complicating Peritonitis.With shiver with cold and jaundice, then prompting may concurrent suppurative pylephlebitis.
(4) tenderness and rebound tenderness abdominal tenderness are the performances that parietal peritoneum is subject to inflammatory stimulus.Namely in right anterior superior iliac spine and umbilicus line, outer 1/3 intersection mcburney point is usually located at mcBurney point.With the variation of vermiform appendix anatomical position, pressure pain point can correspondingly change, but key is Right Lower Abdomen a fixing pressure pain point.Rebound tenderness also claims Blumberg to levy.Patient that is fat or retrocecally appendicitis, tenderness may be comparatively light, but have obvious rebound tenderness.
(5) namely tension of abdominal muscle vermiform appendix suppurates this sign, and during gangrene perforation Complicating Peritonitis, tension of abdominal muscle is particularly remarkable.But old or obese patient's abdominal muscle is more weak, must check simultaneously pleurosternal muscle is contrasted, just can determine whether tension of abdominal muscle.
(6) dermal sensation allergy in early days, especially have when blocking in vermiform appendix chamber, Right Lower Abdomen dermal sensation allergic phenomena can be there is, scope is equivalent to 10th ~ 12 breast myelomere section innervation districts, be positioned at the trigonum that right crista iliaca peak, right pubic crest and umbilicus are formed, also claim Sherren triangle, it does not change because vermiform appendix position is different, as namely vermiform appendix gangrene perforation then disappears at the dermal sensation allergic phenomena of this trigonum.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: appendicitis is fully recovered, sign recovers normal;
Take a turn for the better: appendicitis symptom is clearly better, and hypogastralgia alleviates, and sign is progressively recovered;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy Appendicitis Patients 41 example of the present invention, effective 36 examples of result, obvious effective rate is 87.80%, and take a turn for the better 4 examples, and improvement rate is 9.76%, and invalid 1 example, total effective rate is 97.56%.
Claims (3)
1. treat a typhlitic medicine, its feature is asked and is: it is made up of the medicine original in following weight range:
Flos Chrysanthemi Indici 15-20 gram of Herba Patriniae 15-20 gram of Cortex Lycii 15-25 gram
Flos Carthami 8-15 gram of Herba Taraxaci 15-25 gram of Semen Coicis 25-35 gram
Flos Lonicerae 20-25 gram of Radix Scutellariae 10-15 gram of Radix Angelicae Sinensis 10-20 gram
Herba Hedyotidis Diffusae 20-30 gram of Rhizoma Drynariae 20-25 gram of Herba Violae 10-15 gram
Radix Cirsii Japonici 10-15 gram of Radix Et Rhizoma Rhei 10-20 gram of Radix Bupleuri 8-15 gram
Radix Trichosanthis 15-20 gram of Caulis Sargentodoxae 20-25 gram of Fructus Forsythiae 15-20 gram
Semen Benincasae 15-20 gram of Semen Persicae 8-15 gram of Rhizoma Acori Graminei 10-15 gram
Cortex Magnoliae Officinalis 10-20 gram of Radix Glycyrrhizae 10-20 gram of Radix Paeoniae Alba 9-15 gram
Caulis Lonicerae 15-25 gram of Rhizoma Zingiberis Recens 10-15 gram of Herba Taxilli 10-20 gram
Pericarpium Citri Reticulatae 6-10 gram of Semen Pruni 10-20 gram of Fructus Aurantii 6-12 gram
Rhizoma Imperatae 15-25 gram of Herba Andrographis 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Flos Chrysanthemi Indici 20 grams of Herba Patriniaes 15 grams of Cortex Lycii 20 grams
Flos Carthami 10 grams of Herba Taraxacis 20 grams of Semen Coiciss 30 grams
Flos Lonicerae 20 grams of Radix Scutellariaes 15 grams of Radix Angelicae Sinensis 15 grams
Herba Hedyotidis Diffusae 25 grams of Rhizoma Drynariae 20 grams of Herba Violaes 15 grams
Radix Cirsii Japonici 15 grams of Radix Et Rhizoma Rhei 15 grams of Radix Bupleuri 10 grams
Radix Trichosanthis 20 grams of Caulis Sargentodoxae 25 grams of Fructus Forsythiaes 18 grams
Semen Benincasae 20 grams of Semen Persicaes 10 grams of Rhizoma Acori Graminei 12 grams
Cortex Magnoliae Officinalis 15 grams of Radix Glycyrrhizaes 15 grams of Radix Paeoniae Albas 12 grams
Caulis Lonicerae 20 grams of Rhizoma Zingiberis Recenss 10 grams of Herba Taxillis 15 grams
Pericarpium Citri Reticulatae 8 grams of Semen Prunis 15 grams of Fructus Aurantiis 9 grams
Rhizoma Imperatae 20 grams of Herba Andrographis 15 grams.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Flos Chrysanthemi Indici: remove impurity, removing undesirable root, cleans cutting, dries;
(2) Herba Patriniae: get crude drug, removing impurity, with Water spray, slightly dries in the air, and cutting is dry;
(3) Cortex Lycii: pick decontamination and core, slightly wash, cutting, dry;
(4) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(5) Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
(6) Semen Coicis (parched): get and pick clean Semen Coicis and put in pot and fry to micro-yellow with slow fire, take out, cool, or with wheat bran with stir-fry also can, every Semen Coicis 100 jin, with 10 jin, wheat bran;
(7) Flos Lonicerae: sieve removes silt, picks clean impurity;
(8) Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and run through rear section and dry, attention is avoided tanning by the sun excessively rubescent;
(9) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(10) Herba Hedyotidis Diffusae: get crude drug, removing impurity, wash quickly is clean, slightly dries in the air, cutting, dry, sieve dedust bits;
(11) Rhizoma Drynariae: remove sediment contamination, cleans, slightly soaks, run through, and section, dries;
(12) Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
(13) Radix Cirsii Japonici: pick decontamination, clear water is cleaned, and runs through, cutting, dries;
(14) Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;
(15) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry;
(16) Radix Trichosanthis: pick decontamination, size block is separately, saturating with blister about sixty percent, pulls out, and moistening is even to inside and outside humidity, and section, dries; Or wash, pull out, shine extremely dry, be pounded fritter;
(17) Caulis Sargentodoxae: be soaked in water, cleans spare, runs through, and section, dries;
(18) Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
(19) Semen Benincasae: pick clean impurity, the used time smashs to pieces, or fry to yellow-white with slow fire, put dry place;
(20) Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
(21) Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
(22) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
(23) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
(24) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(25) Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;
(26) Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
(27) Herba Taxilli: wash, runs through, and cutting is dried;
(28) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(29) Semen Pruni: sieve removes spare, wash in a pan clean, pick clean impurity and broken shell, dry, the used time smashs to pieces;
(30) Fructus Aurantii: removing flesh, core, cleans, slightly soaks, pull out, soften, and till pinching doubling with hands, section, dries;
(31) Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;
(32) Herba Andrographis: removing impurity, cleans, cutting, dry;
(2) prepare
(1) Flos Chrysanthemi Indici of described weight, Herba Patriniae, Cortex Lycii, Flos Carthami, Herba Taraxaci, Semen Coicis, Flos Lonicerae, Radix Scutellariae, Radix Angelicae Sinensis, Herba Hedyotidis Diffusae, Rhizoma Drynariae, Herba Violae, Radix Cirsii Japonici, Radix Et Rhizoma Rhei, Radix Bupleuri, Radix Trichosanthis, Caulis Sargentodoxae, Fructus Forsythiae, Semen Benincasae, Semen Persicae, Rhizoma Acori Graminei, Cortex Magnoliae Officinalis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Caulis Lonicerae, Rhizoma Zingiberis Recens, Herba Taxilli, Pericarpium Citri Reticulatae, Semen Pruni, Fructus Aurantii, Rhizoma Imperatae, Herba Andrographis medicine are added 8 times of water gagings and soak, soak after 90 minutes, intense fire decocts boiling 10 minutes, then within 20 minutes, filters to obtain decoction liquor for the first time with slow fire boiling;
(2) add water the medicinal residues of filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) twice decoction liquor is merged, then simmer in water 10 minutes and get final product.
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Application publication date: 20150325 |