CN104208307A - Chinese patent medicine treating gout - Google Patents
Chinese patent medicine treating gout Download PDFInfo
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- CN104208307A CN104208307A CN201410404235.7A CN201410404235A CN104208307A CN 104208307 A CN104208307 A CN 104208307A CN 201410404235 A CN201410404235 A CN 201410404235A CN 104208307 A CN104208307 A CN 104208307A
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Abstract
A Chinese patent medicine treating gout is composed of extractives of traditional Chinese medicine plants semen plantaginis, rhizoma alismatis, panax notoginseng, radix bupleuri, fructus gardenia, cortex moutan, akebia stem, radix scutellariae and radix rehmanniae. The disease mechanism of gout is dampness-heat of liver channel, the therapeutic principle is to clear dampness heat of liver channel, activate blood and free the collateral vessels. The Chinese patent medicine treating gout is capable of promoting drainage of uric acid by human body, avoiding coalescence of uric acid from, and preventing formation of tophus and joint deformities, and is capable of improving gout physique and breaking gout diet taboo after being taken for a period. Compared with western medicines, the Chinese patent medicine is rapid and durable in treatment effect, free of side effect, low in cost and convenient to administrate and carry, and is capable of thoroughly improving gout physique. After the Chinese patent medicine is continuously administrated for a period, a patient can dine like common healthy people and is not restricted on the aspects of purine-rich food such as beer, seafood, beans and the like, so that the diet habit of patients is maintained and the life quality of patients is guaranteed.
Description
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicinal capsule for the treatment of gout.
Background technology
Gout is that a kind of because of the caused disease of purine metabolic disturbance for a long time, its sickness rate raises year by year, from 1998 0.34% rise to 2003 1.33%.According to statistics, domestic patient with gout approximately has 1,200 ten thousand, is the more common metabolic diseases of person in middle and old age.Performance has acute arthritis repeatedly to show effect clinically, gout calculus, joint deformity, gouty nephropathy, or gouty arthritis,chronic is accompanied acute attack repeatedly, blood uric acid Enrichment.Pain person is owing to there being tophus deposition to cause joint distortion for a long time.。
Along with people's living standard improves, gout has become the common frdquently encountered disease of serious threat health of people gradually.Gout is to eat the metabolic disease coming, and is difficult to eradicate once suffer from.The pathogenetic key link of gout is that the not normal caused blood uric acid of metabolism is too high.The too high person of China's blood uric acid approximately has 1.2 hundred million (accounting for 10% of total population, suitable with Hesperian 2-18%).Wherein the Patients with Hyperuricemia of 5-12% can develop into gout.Although the patient that most of blood uric acid raises is without any symptom, just in the time checking, find, it is normal with the metabolic disease such as obesity, essential hypertension, type Ⅱdiabetes mellitus and deposit that no conscious sympton does not develop into the hyperuricemia of gout, it is also atherosclerotic risk factor, increases the weight of the infringement of the vitals such as cardiovascular and kidney.
Before gout outbreak, without sign, once outbreak, pain is very violent, sore spot arthroncus, erythrosis, hot.Acute gout joint property more than 90% shows as single arthralgia, the most common with the first metatarsophalangeal joints, and other joints are followed successively by instep, ankle joint, heel, knee joint, carpal joint, finger.Gout shows joint conventionally, further develops and also can have influence on other internal organs, commonly kidney.The uric acid of being grown up every day has 2/3 to be that uric acid content increases by renal excretion (discharging approximately 210 milligrams of UANs), will increase the weight of kidney burden.In addition, the crystallization of uric acid not only can be deposited in joint, also can be deposited on kidney, forms renal calculus, finally develops into gouty nephropathy.
The food of long-term edible high purine, comprise that medicated beer, Chinese liquor, Seem Lablab Album, dry bean, seafood, pluck and meat soup etc. cause hyperuricemia and gout, therefore, patient's diet control is most important, and the change of diet and life style is the important step of hyperuricemia and gout control.The food of medically patient with gout being advocated to be rich in without the diet of purine or low purine or restriction purine, still, when people take at restriction purine, has also limited the absorption of protein.The absorption of strict erstricted diet can make serum uric acid level decline 10-15%, and effectively controls the outbreak of gout.But, change in order to control gout outbreak the dietary habit of forming for many years, once particularly the dietary habit of long-term fish and shrimp wine meat is forced restriction, for a lot of patient with gout, be all the very painful thing of part.
Doctor trained in Western medicine adopts colchicine conventionally to the treatment of gout acute attack, and this medicine is gout specific treatment, the most frequently used.Side effect is gastrointestinal irritation and erythra, dizziness, headache etc., has ulcer patient forbidding.Gout interictal and chronic phase treatment: diet control and colchicine prophylactic treatment, though can prevent acute arthritis recurrence, but do not reduce hyperuricemia concentration and increase uric acid output, and can not control tophaceous formation and the damage of hyperuricemia to kidney.Therefore,, except diet control, also must adopt releasing uric acid and suppress the synthetic Drug therapy of uric acid at interictal.Representative drugs: 1, probenecid sheet, for hyperuricemia companion's gouty arthritis,chronic and tophus.Untoward reaction be feel sick, vomiting etc., and can promote renal calculus to form.For ensureing that urine PH value maintains 6.0 ~ 6.5, need great quantity of water drinking and take the medicine of alkalized urine, in case renal calculus.2, benzbromarone capsule: cure mainly non-stage of attack of gouty arthritis, can be used for having the light patient with gout to moderate renal insufficiency.The side effect of this medicine is to have gastrointestinal reaction.3, Allopurinol Tablets: for outbreak or chronic gout person suffer from tophus repeatedly.Untoward reaction is gastrointestinal reaction, erythra, leukopenia, and other have alopecia, heating, lymphadenectasis, liver to increase.Take the interim uric acid transitivity gout outbreak that sometimes can occur, must be aided with Effects of Colchicine In Treating.
From above-mentioned, although the chemotherapy gout successful of Western medicine, because larger side effect makes quite a few patient with gout have to abandon use.
Chinese medicine gout long history, existing Chinese traditional treatment: often taking dampness removing analgesic drug product as main, coordinate western medicine; Or spread on the joint of getting involved with promoting blood circulation and stopping pain medicine for external use.Although the determined curative effect of Chinese traditional treatment gout for many years, lays under tribute always.
Summary of the invention
In view of current western medicine gout has stronger side effect, and the present situation that Chinese traditional treatment gout lays under tribute always, the object of the invention is the powerful advantages of the treating both the principal and secondary aspects of a disease of developing Chinese medicine, develop a kind of analgesic effect uniqueness, instant effect, can change status arthriticus, extend for a long time gout duration of seizure interval and without obvious toxic-side effects, take, the Chinese patent medicine for the treatment of gout easy to carry.
The present invention is a kind of Chinese patent medicine for the treatment of gout, it is characterized in that, this medicine is made up of the extract of Chinese medicinal plant Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae and the Radix Rehmanniae, and the weight portion of each taste Chinese medicine extract is as follows:
Semen Plantaginis 2.8--3.5 Rhizoma Alismatis 2.8--3.5 Radix Notoginseng 2.5--3.2 Radix Bupleuri 2.5--3.2 Fructus Gardeniae 2.0--3.3
Cortex Moutan 2.5--3.3 Caulis Akebiae 2.8--3.3 Radix Scutellariae 3.5--4.3 Radix Rehmanniae 3.6--4.5.
The Chinese patent medicine of this treatment gout can be made into capsule, tablet, pill, granule, decoction.
Adopt the Chinese patent drugs for treatment patient with gout of this treatment gout, all received desirable therapeutic effect, through clinical observation, this medical instrument has following effect:
1, promote the excretion of body to uric acid, can significantly reduce serum uric acid level after taking the several months;
2, stop uric acid coalescent, prevent tophaceous formation and joint distortion;
3, change status arthriticus, break gouty diet taboo;
4, effective percentage absolutely, has no toxicity and occurs;
5, curative effect is lasting, obviously extends the interval time of gout morbidity;
6, cost is low, takes, easy to carry.
Common most of patient with gout showed effect to having in two years for the second time in half a year.In the numerical example patient who takes this medicine, have no more than a year recurrence, take after a period of time, even if eaten the food that is rich in purine, as long as appropriate, all there is no gout outbreak, be deeply subject to patient's favorable comment.Even if some patients were outbreak, symptom also obviously alleviates.
Compare with Western medicine, the Chinese patent medicine curative effect of this treatment gout rapidly, lasting, have no side effect, cost is low, it is easy to carry to take, can be from improve status arthriticus with this, take after a period of time patient can be as common Healthy People diet and need not limit especially edible medicated beer, seafood, the contour purine food of beans, thereby maintained patient's Diet lifestyle, ensured patient's quality of life.
Detailed description of the invention
embodiment 1
By Chinese crude drug Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae, the Radix Rehmanniae, boil through conventional production process, concentrated, dry, beat the extract of the each Chinese medicine constituent obtaining after each procedure of powder, according to prescription: 2.8 kilograms of Semen Plantaginis, 3.5 kilograms of Rhizoma Alismatis, 3.0 kilograms of Radix Notoginseng, 3.2 kilograms of Radix Bupleuri, 2.0 kilograms of Fructus Gardeniaes, 2.5 kilograms of Cortex Moutans, 2.8 kilograms of Caulis Akebiaes, 4.0 kilograms of Radix Scutellariaes, 4.5 kilograms, the Radix Rehmanniae, the powdered extract of every Chinese medicine is taken to rear abundant mix homogeneously, adopt No. 0 hard capsulae vacuus, with the weight standard filling of 0.48 gram every, packaging, make the Chinese medicine capsule for the treatment of gout of the present invention.10 degrees Celsius of Drug Manufacturing Room's temperature, relative humidity 35%.
Embodiment 2
By Chinese crude drug Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae, the Radix Rehmanniae, boil through conventional production process, concentrated, dry, beat the extract of the each Chinese medicine constituent obtaining after each procedure of powder, according to prescription: 3.5 kilograms of Semen Plantaginis, 2.9 kilograms of Rhizoma Alismatis, 3.2 kilograms of Radix Notoginseng, 2.5 kilograms of Radix Bupleuri, 3.0 kilograms of Fructus Gardeniaes, 2.8 kilograms of Cortex Moutans, 3.0 kilograms of Caulis Akebiaes, 4.3 kilograms of Radix Scutellariaes, 3.8 kilograms, the Radix Rehmanniae, the powdered extract of each taste Chinese medicine is taken to rear abundant mix homogeneously, adopt No. 0 hard capsulae vacuus, with the weight standard filling of 0.48 gram every, packaging, make the Chinese medicine capsule for the treatment of gout of the present invention.24 degrees Celsius of Drug Manufacturing Room's temperature, relative humidity 65%.
Embodiment 3
By Chinese crude drug Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae, the Radix Rehmanniae, boil through conventional production process, concentrated, dry, beat the extract of the each Chinese medicine constituent obtaining after each procedure of powder, according to prescription: 3.0 kilograms of Semen Plantaginis, 3.2 kilograms of Rhizoma Alismatis, 3.1 kilograms of Radix Notoginseng, 2.8 kilograms of Radix Bupleuri, 3.3 kilograms of Fructus Gardeniaes, 2.6 kilograms of Cortex Moutans, 2.9 kilograms of Caulis Akebiaes, 3.5 kilograms of Radix Scutellariaes, 4.2 kilograms, the Radix Rehmanniae, the powdered extract of each taste Chinese medicine is taken to rear abundant mix homogeneously, adopt No. 0 hard capsulae vacuus, with the weight standard filling of 0.48 gram every, packaging, make the Chinese medicine capsule for the treatment of gout of the present invention.20 degrees Celsius of Drug Manufacturing Room's temperature, relative humidity 45%.
Embodiment 4
By Chinese crude drug Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae, the Radix Rehmanniae, boil through conventional production process, concentrated, dry, beat the extract of the each Chinese medicine constituent obtaining after each procedure of powder, according to prescription: 3.2 kilograms of Semen Plantaginis, 3.1 kilograms of Rhizoma Alismatis, 2.5 kilograms of Radix Notoginseng, 3.0 kilograms of Radix Bupleuri, 3.2 kilograms of Fructus Gardeniaes, 3.0 kilograms of Cortex Moutans, 3.2 kilograms of Caulis Akebiaes, 3.6 kilograms of Radix Scutellariaes, 4.0 kilograms, the Radix Rehmanniae, the powdered extract of each taste Chinese medicine is taken to rear abundant mix homogeneously, adopt No. 0 hard capsulae vacuus, with the weight standard filling of 0.48 gram every, packaging, make the Chinese medicine capsule for the treatment of gout of the present invention.18 degrees Celsius of Drug Manufacturing Room's temperature, relative humidity 50%.
Embodiment 5
By Chinese crude drug Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae, the Radix Rehmanniae, boil through conventional production process, concentrated, dry, beat the extract of the each Chinese medicine constituent obtaining after each procedure of powder, according to prescription: 3.4 kilograms of Semen Plantaginis, 3.0 kilograms of Rhizoma Alismatis, 2.7 kilograms of Radix Notoginseng, 3.1 kilograms of Radix Bupleuri, 2.8 kilograms of Fructus Gardeniaes, 3.2 kilograms of Cortex Moutans, 3.3 kilograms of Caulis Akebiaes, 4.1 kilograms of Radix Scutellariaes, 3.6 kilograms, the Radix Rehmanniae, the powdered extract of each taste Chinese medicine is taken to rear abundant mix homogeneously, adopt No. 0 hard capsulae vacuus, turn and fill out with the weight standard of 0.48 gram every, packaging, make the Chinese medicine capsule for the treatment of gout of the present invention.22 degrees Celsius of Drug Manufacturing Room's temperature, relative humidity 60%.
Embodiment 6
By Chinese crude drug Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae, the Radix Rehmanniae, boil through conventional production process, concentrated, dry, beat the extract of the each Chinese medicine constituent obtaining after each procedure of powder, according to prescription: 3.3 kilograms of Semen Plantaginis, 2.8 kilograms of Rhizoma Alismatis, 2.9 kilograms of Radix Notoginseng, 3.2 kilograms of Radix Bupleuri, 2.5 kilograms of Fructus Gardeniaes, 3.3 kilograms of Cortex Moutans, 3.1 kilograms of Caulis Akebiaes, 4.2 kilograms of Radix Scutellariaes, 4.4 kilograms, the Radix Rehmanniae, the powdered extract of each taste Chinese medicine is taken to rear abundant mix homogeneously, adopt No. 0 hard capsulae vacuus, with the weight standard filling of 0.48 gram every, packaging, make Chinese medicine capsule of the present invention.20 degrees Celsius of Drug Manufacturing Room's temperature, relative humidity 65%.
Model case:
Case 1:
Rely certain, man, 46 years old, to live irregular, dinner party is many.Diet is taking meat, seafood as main, and medicated beer must be drunk especially every night.Early summer the year before, when he escort the late into the night client sottish go home, lie on a bed and prepare in bed, suddenly a burst of by right crus of diaphragm toe as lancinate as grieved pain pain break into a sweat.While getting up to check, find that large area redness appears in right crus of diaphragm big toe periarticular and soft tissue, heating pain, household makes a call to quickly 120 and sends to hospital and seek medical advice, and is diagnosed as gout, takes immediately the Chinese medicine capsule for the treatment of gout of the present invention, and pain is alleviated at once.Dosage when acute attack is oral 8 of every day, and the maintenance dose after remission is 4 of every days.Take 4 months, follow up a case by regular visits to and have no a recurrence in, diet is as usual, does not limit high purine food.
Case 2:
49 years old gout of Zhang man 20 years, fish and shrimp, mushroom, beans or drink after gout outbreak, show effect 2-3 time every year, take western medicine and at once alleviate, whenever edible high purine food shows effect again.Take the Chinese medicinal capsule of this treatment gout, take continuously after 4 months, not recurrence in nearly 1 year so far.Do not limit high purine food.
Case 3:
Liu man 45 years old, certain director of group, 10 years medical histories, service needed dinner party is many, often edible medicated beer, Chinese liquor, seafood, meat.Take continuously the Chinese medicine capsule 6 months that the present invention treats gout, have no more than a year recurrence, diet is normal, does not limit high purine food.
Case 4:
Zhang man 38 years old, suffers from gout 8 years.Annual acute attack 3-4 time, takes anti-inflammatory analgesic and alleviates when outbreak.Violent because of patient's gastrointestinal reaction after taking Western medicine, seek medical advice in many places, introduces through friend, takes continuously the Chinese medicine capsule of this treatment gout after 3 months, and effect is remarkable, and no side effects has no recurrence in more than 1 year so far.Diet is normal, does not limit high purine food.
Case 5:
Ma man 45 years old ill 10 years, it is every that because recurring after edible high purine food, pain is hard to bear, and right big toe enlargement distortion is stiff, takes after the Chinese medicine capsule of this treatment gout, and pain relieving is fast, evident in efficacy, medication 1 year, toe joint activity is as usual, not recurrence.Diet does not strictly limit high purine food.
Case 6:
Wish certain man 35 years old ill more than 10 years.Annual acute attack for several times.Take the Chinese medicine capsule 1 year of this treatment gout, successful, no side effects, adheres to taking medicine so far, and diet is normal, does not limit high purine food, and gout remains dormant.
Claims (1)
1. a Chinese patent medicine for the treatment of gout, is characterized in that, this medicine is made up of the extract of Chinese medicinal plant Semen Plantaginis, Rhizoma Alismatis, Radix Notoginseng, Radix Bupleuri, Fructus Gardeniae, Cortex Moutan, Caulis Akebiae, Radix Scutellariae and the Radix Rehmanniae, and the weight portion of each taste Chinese medicine extract is as follows:
Semen Plantaginis 2.8---3.5 Rhizoma Alismatis 2.8---3.5 Radix Notoginseng 2.5---3.2 Radix Bupleuri 2.5---3.2
Fructus Gardeniae 2.0---3.3 Cortex Moutan 2.5---3.3 Caulis Akebiae 2.8---3.3 Radix Scutellariae 3.5---4.3
Radix Rehmanniae 3.6---4.5.
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| CN201410404235.7A CN104208307A (en) | 2014-08-18 | 2014-08-18 | Chinese patent medicine treating gout |
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| CN201410404235.7A CN104208307A (en) | 2014-08-18 | 2014-08-18 | Chinese patent medicine treating gout |
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| CN104208307A true CN104208307A (en) | 2014-12-17 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109820930A (en) * | 2019-03-21 | 2019-05-31 | 广州市士刚食品有限公司 | A kind of anti-trioxypurine formula and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843827A (en) * | 2009-11-25 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating gout |
| CN101843789A (en) * | 2009-11-18 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating gout |
| CN101843754A (en) * | 2009-12-09 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating gout |
| CN102872314A (en) * | 2012-10-28 | 2013-01-16 | 牛健坤 | Drug for treating gout and preparation method for drug |
-
2014
- 2014-08-18 CN CN201410404235.7A patent/CN104208307A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843789A (en) * | 2009-11-18 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating gout |
| CN101843827A (en) * | 2009-11-25 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating gout |
| CN101843754A (en) * | 2009-12-09 | 2010-09-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating gout |
| CN102872314A (en) * | 2012-10-28 | 2013-01-16 | 牛健坤 | Drug for treating gout and preparation method for drug |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109820930A (en) * | 2019-03-21 | 2019-05-31 | 广州市士刚食品有限公司 | A kind of anti-trioxypurine formula and preparation method thereof |
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Application publication date: 20141217 |