CN103263655A

CN103263655A - Chinese medicine composition for treating gouty arthritis

Info

Publication number: CN103263655A
Application number: CN2013102135066A
Authority: CN
Inventors: 石欣
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-06-03
Filing date: 2013-06-03
Publication date: 2013-08-28

Abstract

The invention provides a Chinese medicine composition for treating gouty arthritis. The Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: 20 parts of radix clematidis, 10 parts of radix aconiti preparata, 9 parts of carthamus tinctorius, 20 parts of sargent gloryvine, 12 parts of edible tulip, 20 parts of coix seed, 20 parts of medicinal cyathula root, 30 parts of lysimachia christinae hance, 20 parts of yam rhizome, 30 parts of rhizoma smilacis glabrae, 20 parts of ash bark, 20 parts of grifola, 6 parts of long pepper, 20 parts of caulis sinomenii, 15 parts of the root of fangji, 20 parts of rhizoma alismatis, 20 parts of plantain herb, 15 parts of bark of himalayan coralbean, 9 parts of rhizoma sparganii, 15 parts of semen plantaginis, 10 parts of mountain spicy tree fruit, 9 parts of rhizoma pinelliae preparata, 10 parts of golden cypress, 12 parts of rhizoma corydalis, 12 parts of root of common peony, 15 parts of cortex acanthopanacis, 15 parts of rhizoma atractylodis, 12 parts of loranthus parasiticus, 6 parts of rheum officinale, 12 parts of the root bark of the peony tree, 12 parts of radix angelicae pubescentis, 25 parts of dried ginger, 15 parts of Chinese angelica and 20 parts of ramulus mori. The Chinese medicine composition is remarkable in treatment effect and high in clinical cure rate.

Description

A kind of Chinese medicine composition for the treatment of gouty arthritis

Technical field

The present invention relates to a kind of medicine for the treatment of gout, be specifically related to a kind of Chinese medicine composition of the treatment gouty arthritis that is prepared from by Chinese herbal medicine.

Background technology

In recent years, along with growth in the living standard, the change of dietary structure, the prevalence of hyperuricemia and gout day by day increases.Medicine commonly used such as colchicine, nonsteroidal antiinflammatory drug, glucocorticoid etc. are though pain relieving rapidly because toxic and side effects such as hepatorenal damage, GI irritation are bigger, used clinically and is subjected to certain limitation.Acute gouty arthritis is under the jurisdiction of the category of the traditional Chinese medical science " hot fraud ", " gout ", its onset because of interior by delicious food usually excessively, the wet part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels of stopping up, attacked due to people's flesh tendon by damp outward.Chinese traditional treatment is because of its treating both the principal and secondary aspects of a disease and the little favor that more and more is subjected to curing the patient of toxic and side effects, but in the existing medicine, acute gouty arthritis but rarely had medicine evident in efficacy.

Summary of the invention

In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of gouty arthritis of determined curative effect.

The Chinese medicine composition for the treatment of acute gouty arthritis provided by the invention is prepared from by the crude drug of following weight proportion: Radix Clematidis 20, Radix Aconiti Preparata 10, Flos Carthami 9, Caulis Sargentodoxae 20, Pseudobulbus Cremastrae Seu Pleiones 12, Semen Coicis 20, Radix Cyathulae 20, Herba Lysimachiae 30 Rhizoma Dioscoreae Septemlobae 20, Rhizoma Smilacis Glabrae 30, Cortex Fraxini 20, Polyporus 20, Fructus Piperis Longi 6, Caulis Sinomenii 20, Radix Stephaniae Tetrandrae 15, Rhizoma Alismatis 20, Herba Plantaginis 20, Cortex erythrinae 15, rhizoma sparganic 9, Semen Plantaginis 15, cubeb 10, Rhizoma Pinelliae 9, Cortex Phellodendri 10, Rhizoma Corydalis 12, Radix Paeoniae Rubra 12, Cortex Acanthopancis 15, Rhizoma Atractylodis 15, Herba Taxilli 12, Radix Et Rhizoma Rhei 6, Cortex Moutan 12, Radix Angelicae Pubescentis 12,25 parts of Rhizoma Zingiberiss, Radix Angelicae Sinensis 15, Ramulus Mori 20.

Preparation method adopts conventional method water to carry, 1 dose of day clothes.

Clinical data

1 case

Observed 60 routine cases are examined from May, 2008～2013 my gate in year March and the patient of in-patient department.Be divided into treatment group, matched group at random.30 examples are organized in treatment, male's 24 examples wherein, women's 6 examples; 32～67 years old age, average 47.16 ± 9.76 years old; Disease time 4～74 hours.Matched group 30 examples, male's 25 examples wherein, women's 5 examples; 28 ~ 65 years old age, average 44.35 ± 8.63 years old; Disease time 5～72 hours.Two groups of cases are learned processing by statistics, and there was no significant difference (P〉0.05), have comparability.

2 Therapeutic Method

The treatment group: take medicine of the present invention, 1 dose of every day, divide 2 times oral.

Matched group: colchicine, first dose of 1.0mg, per 2 hours 1 time thereafter, each 0.5mg, total amount was no more than 3mg in 24 hours, obeyed till pain relief or gastrointestinal reaction occurs, added and use allopurinol, 0.1g at every turn, every day 3 times.More than two groups all give low purine diet, carry out therapeutic evaluation after treating for 1 week.

3 observation of curative effect

3.1 criterion of therapeutical effect:

Clinical recovery: the symptom complete obiteration, joint function recovery is normal, and the blood uric acid inspection is normal;

Produce effects: cardinal symptom disappears, and function of joint is recovered substantially, and the blood uric acid inspection is normal substantially;

Effectively: cardinal symptom disappears substantially, and main function of joint and blood uric acid inspection make moderate progress;

Invalid: improvement is not seen in symptom and blood uric acid inspection.

3.2 therapeutic outcome: see table 1 for details.As can be known, treatment group total effective rate is better than matched group (P＜0.05) from table.

Group	The example number	Recovery from illness	Produce effects	Effectively	Invalid	Total effective rate
							The treatment group	30	8	17	4	1	96.67%
Matched group	30	3	9	10	8	73.33%

Compare P＜0.05 with matched group.

The specific embodiment

Be further introduced below in conjunction with the present invention of embodiment.

Embodiment 1

Get Radix Clematidis 20 by weight, Radix Aconiti Preparata 10, Flos Carthami 9, Caulis Sargentodoxae 20, Pseudobulbus Cremastrae Seu Pleiones 12, Semen Coicis 20, Radix Cyathulae 20, Herba Lysimachiae 30 Rhizoma Dioscoreae Septemlobae 20, Rhizoma Smilacis Glabrae 30, Cortex Fraxini 20, Polyporus 20, Fructus Piperis Longi 6, Caulis Sinomenii 20, Radix Stephaniae Tetrandrae 15, Rhizoma Alismatis 20, Herba Plantaginis 20, Cortex erythrinae 15, rhizoma sparganic 9, Semen Plantaginis 15, cubeb 10, Rhizoma Pinelliae 9, Cortex Phellodendri 10, Rhizoma Corydalis 12, Radix Paeoniae Rubra 12, Cortex Acanthopancis 15, Rhizoma Atractylodis 15, Herba Taxilli 12, Radix Et Rhizoma Rhei 6, Cortex Moutan 12, Radix Angelicae Pubescentis 12,25 parts of Rhizoma Zingiberiss, Radix Angelicae Sinensis 15, Ramulus Mori 20; The decocting that adds 10 times, 8 times amounts boils 2 times, and each two hours, collecting decoction, being concentrated into relative density is that 1.05-1.15 is standby.

Claims

1. Chinese medicine composition for the treatment of gouty arthritis, it is characterized in that, be prepared from by the crude drug of following weight proportion: Radix Clematidis 20, Radix Aconiti Preparata 10, Flos Carthami 9, Caulis Sargentodoxae 20, Pseudobulbus Cremastrae Seu Pleiones 12, Semen Coicis 20, Radix Cyathulae 20, Herba Lysimachiae 30 Rhizoma Dioscoreae Septemlobae 20, Rhizoma Smilacis Glabrae 30, Cortex Fraxini 20, Polyporus 20, Fructus Piperis Longi 6, Caulis Sinomenii 20, Radix Stephaniae Tetrandrae 15, Rhizoma Alismatis 20, Herba Plantaginis 20, Cortex erythrinae 15, rhizoma sparganic 9, Semen Plantaginis 15, cubeb 10, Rhizoma Pinelliae 9, Cortex Phellodendri 10, Rhizoma Corydalis 12, Radix Paeoniae Rubra 12, Cortex Acanthopancis 15, Rhizoma Atractylodis 15, Herba Taxilli 12, Radix Et Rhizoma Rhei 6, Cortex Moutan 12, Radix Angelicae Pubescentis 12,25 parts of Rhizoma Zingiberiss, Radix Angelicae Sinensis 15, Ramulus Mori 20.