CN108186863A - A kind of Chinese medicine for treating psoriasis - Google Patents

A kind of Chinese medicine for treating psoriasis Download PDF

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Publication number
CN108186863A
CN108186863A CN201810264285.8A CN201810264285A CN108186863A CN 108186863 A CN108186863 A CN 108186863A CN 201810264285 A CN201810264285 A CN 201810264285A CN 108186863 A CN108186863 A CN 108186863A
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grams
radix
psoriasis
chinese medicine
treatment
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邓娟
张跃响
李伟
都启龙
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Shangqiu Kang Du Skin Disease Research Institute
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Shangqiu Kang Du Skin Disease Research Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention discloses a kind of Chinese medicines for treating psoriasis, are made of the raw material of following weight, 12 15 grams of Radix Angelicae Sinensis, 10 12 grams of cicada slough, 13 15 grams of radix rehmanniae recen, 8 10 grams of rhizoma anemarrhenae, 8 10 grams of Radix Salviae Miltiorrhizae, 20 22 grams of cornu bubali, 8 10 grams of kuh-seng, windproof 10 12 grams, 10 12 grams of Poria cocos, 10 12 grams of the root bark of shaggy-fruited dittany, 20 25 grams of dandelion, 8 10 grams of the radix paeoniae rubrathe, 8 10 grams of honeysuckle and Radix Glycyrrhizae 36 are restrained into preparation method is to decoct.One dose per day.The present invention fundamentally solves the treatment of wind-heat blood-head psoriasis pustulosa with drug by dialectical.Accelerate skin lesion reparation, dispel the scales of skin that peel off, antipruritic nti-freckle shortening treatment cycle and other effects.

Description

A kind of Chinese medicine for treating psoriasis
Technical field
The invention belongs to field of medicaments, more particularly, to a kind of Chinese medicine for treating psoriasis.
Background technology
Psoriasis is called psoriasis, and the traditional Chinese medical science is known as " white arrange ", refers to occur the drying of multilayer silvery white in erythema repeatedly The chronic recurrent inflammatory dermatoses of the scales of skin that peel off, ancient medicine writings also have referred to as psoriasis, snake lice, white shell sore.Blood-head psoriasis pustulosa Clinically to quickly grow, fash is scarlet, layer by layer the scales of skin that peel off, acute pruritus, and the scales of skin that peel off is stripped off, sieve-like blutpunkte is classical symptom.Disease Journey is long, easily recurs.This disease is a kind of disease of multifactorial inheritance, and immune-mediated is its main mechanism, and risk factor is complicated more Sample, it is related with bacteriovirus infection, inherent cause, stress and immunologic function disorder.This disease incidence is higher, is easy to multiple Hair, the course of disease is longer, is more especially to invade person between twenty and fifty, the health and spirit harm to patient are very big.This disease of western medical treatment with Based on antitumor drug, corticosteroid, vitamin A acid, immunosuppressor etc., side effect is big, and easily forms drug resistance and dependence Property.Facts have proved psoriasis is the advantage disease of the traditional Chinese medical science, and diagnosis and treatment obtains preferable therapeutic effect.
The Chinese patent of application number 201510204216.4 discloses a kind of drug for being used to treat blood-head psoriasis pustulosa, Its bulk pharmaceutical chemicals forms:20-30 grams of radix rehmanniae recen, 20-30 grams of gypsum, 10-15 grams of Asian puccoon, 6-9 grams of Radix Glycyrrhizae, 10-15 grams of the radix paeoniae rubrathe, 6-9 grams of rhizoma anemarrhenae, 6-9 grams windproof, 10-15 grams of the root bark of shaggy-fruited dittany, 10-15 grams of Radix Salviae Miltiorrhizae, 6-9 grams of zaocys dhumnade, 10-15 grams of folium isatidis, plate are blue 10-15 grams of root, 6-9 grams of trigone, 10-15 grams of radix scrophulariae, 10 grams of smilax, 12 grams of the root of bidentate achyranthes, 15 grams of honeysuckle, connects 6-9 grams of moutan bark Stick up 15 grams.The invention advantageous effect is treatment blood-head psoriasis pustulosa, and Small side effects, recurrence rate is low, is currently treatment blood-heat type silver Consider a kind of newtype drug of disease to be worth doing.
On the basis of the existing research of Treating Psoriasis with Chinese Drugs, we pass through the continuous exploration of more than two decades, dialectical treatment This disease has accumulated abundant clinical experience, and present invention treatment blood-head psoriasis pustulosa has cure rate high, and Small side effects are uneasy to recur Advantage, and do not generate drug resistance, be the important development direction for treating psoriasis now.
Invention content
In view of this, in view of the deficiencies of the prior art, it is an object of the present invention to provide a kind of Chinese medicines for treating psoriasis, lead to It crosses dialectical, wind-heat blood-head psoriasis pustulosa is fundamentally solved the problems, such as with drug.
In order to achieve the above objectives, the present invention uses following technical scheme:
A kind of Chinese medicine for treating psoriasis, is made of the raw material of following weight, 12-15 grams of Radix Angelicae Sinensis, 10-12 grams of cicada slough, raw 13-15 grams of glutinous rehmannia, 8-10 grams of rhizoma anemarrhenae, 8-10 grams of Radix Salviae Miltiorrhizae, 20-22 grams of cornu bubali, 8-10 grams of kuh-seng, windproof 10-12 grams, Poria cocos 10-12 grams, 10-12 grams of the root bark of shaggy-fruited dittany, 20-25 grams of dandelion, 8-10 grams of the radix paeoniae rubrathe, 8-10 grams of honeysuckle and Radix Glycyrrhizae 3-6 restrain into, Preparation method is to decoct.One dose per day.
Pharmacological effect
Radix Angelicae Sinensis:
Nature and flavor:Radix Angelicae Sinensis is sweet in flavor, pungent, warm-natured.
Channel tropism:Return liver warp, the heart channel of Hang-Shaoyin, the spleen channel.
Effect:1. tonifying blood and regulating menstruation, pale complexion, irregular menstruation etc. caused by the deficiency of blood is controlled, often with prepared rehmannia root, Radix Astragali, Radix Paeoniae Alba is equally used.2. promoting blood circulation and stopping pain, with traumatic injury is controlled, blood stasis and swelling pain is often equal with frankincense, myrrh, peach kernel and uses;Cold stagnant channels and collaterals Numbness pain, be often equal with Rhizoma Chuanxiong, cassia twig, asarum and use.3. relax bowel the dry constipation of intestines caused by blood deficiency and depleted fluid is controlled, often with meat desert Rong, brush-cherry seed, Fructus Aurantii are the same as use.
Cicada slough:
Nature and flavor:It is sweet in flavor, it is cold in nature.
Channel tropism:Return lung, Liver Channel.
Effect:Effect:Relieving the exterior syndrome with drugs pungent in flavor and cool in property Chinese medicine cicada slough has diverging wind-heat, and promoting eruption is antipruritic, removing nebula, relieving convulsion and spasm. It cures mainly:For affection of exogenous wind-heat, warm disease is from the beginning of, measles without adequate eruption, rubella itch, hot eyes, mesh screen, nocturnal fretfulness in infants, lockjaw.
Radix rehmanniae recen
Nature and flavor:It is sweet in flavor, bitter, it is cold in nature.
Channel tropism:The thoughts of returning home, liver and kidney channel.
Effect:1. clearing heat and cooling blood with high fever coma caused by warm disease heat enters ying blood is controlled, is often equal with cornu bubali, radix scrophulariae With;Bleeding from five sense organs or subcutaneous tissue caused by blood-heat bleeding is had blood in stool, and is often equal with moutan bark, the radix paeoniae rubrathe, cornu bubali and is used.2. nourishing Yin and promoting production of body fluid, with controlling consumption of body fluid caused by febrile disease And the thirsty, constipation that generates heat caused by yin asthenia generating intrinsic heat, often with radix scrophulariae, Radix Ophiopogonis, radix polygonati officinalis with use;Osteopyrexia and fever, can be with turtle shell, sweet wormwood It is equivalent to use.
Rhizoma anemarrhenae
Nature and flavor:It is bitter, sweet, it is cold in nature.
Channel tropism:Return lung, stomach, kidney channel.
Effect:1. clearing heat-fire, with lung stomach Qi point real heat is controlled, often with gypsum compatibility;It is coughed up caused by lung heat and spits yellow phlegm, Often it is equal with radix scutellariae, Snakegourd Fruit, cape jasmine and uses.2. nourishing yin and lessening fire osteopyrexia and fever caused by the deficiency of Yin is controlled, mostly with Cortex Phellodendri, radix rehmanniae recen, tortoise plastron It is equivalent to use.3. fluid dryness with interior thermal burn Tianjin and diabete is controlled, is often equally used with gypsum, pueraria lobata, Radix Ophiopogonis;Dry constipation of intestines, often It is equal with Radix Polygoni Multiflori, Radix Angelicae Sinensis, fructus cannabis and uses.
Radix Salviae Miltiorrhizae
Nature and flavor:Bitter, cold nature.
Channel tropism:The thoughts of returning home, pericardium, Liver Channel.
Effect:1. invigorate blood circulation with amenorrhea due to stagnation of blood, dysmenorrhoea and postpartum stasis of blood is controlled, can be applied alone this product to grind clothes. 2. stasis-dispelling and pain-killing with chest impediment and cardialgia is controlled, is often equal with safflower, Rhizoma Chuanxiong, the radix paeoniae rubrathe and uses;Traumatic injury, hemostasis are had a pain, often with Radix Angelicae Sinensis, Frankincense, myrrh are equally used.3. cool blood detumescence with sore carbuncle swells are controlled, is often equal with honeysuckle, Fructus Forsythiae, the root of Dahurain angelica, the radix paeoniae rubrathe and uses;Rheumatism Hot numbness is often equal with caulis lonicerae, the radix paeoniae rubrathe, ramulus mori and uses.4. relieving restlessness that clears away heart-fire, with dysphoria and insomnia caused by heat disturbs the mind is controlled, often and gold and silver Flower, Radix Ophiopogonis are equally used.
Cornu bubali
Nature and flavor:Bitter, it is cold in nature.
Channel tropism:Converge to heart and liver channels.
Effect:Heat-clearing;Removing toxic substances;Cool blood;Arresting convulsion.Main pyreticosis headache;The hot coma of quotient;Spot dermexanthesis;It spits blood, bleeding from five sense organs or subcutaneous tissue; Stagnant heat is turned to be yellow;Child convulsion and abscess of throat;Aphthae.
Kuh-seng
Nature and flavor:Bitter, it is cold in nature.
Channel tropism:The thoughts of returning home, liver, stomach, large intestine, bladder warp.
Effect:Effect:Heat-clearing and damp-drying drug sophora flavescens ait has that heat-clearing bath is wet, wind dispelling insecticide, diuresis.It cures mainly:For lower coke It is damp and hot, under band, pruritus vulvae, pruitus, mange, puckery pain of heat gonorrhea
It is windproof
Nature and flavor:Acrid flavour, sweet, slightly warm in nature.
Channel tropism:Return bladder, liver, the spleen channel.
Effect:Effect:It expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis.It cures mainly:For diseases caused by external factors exterior syndrome, rubella itch, rheumatism Numbness pain, lockjaw.
Poria cocos
Nature and flavor:It is sweet in flavor, light, it is mild-natured.
Channel tropism:The thoughts of returning home, spleen, kidney channel.
Effect:1. clearing damp and promoting diuresis with oedema turgor, difficult urination is controlled, is often equal with umbellate pore furgus, rhizoma alismatis, Rhizoma Atractylodis Macrocephalae and uses.2. Bowl spares invigorating the spleen:With the anorexia and loose stool for controlling the insufficiency of the spleen with overabundance of dampness, often it is equal with Radix Codonopsis, Rhizoma Atractylodis Macrocephalae and uses.3. antitoxic heart-soothing and sedative, with control palpitation and severe palpitation, Insomnia forgetfulness etc. is often equal with arillus longan, spina date seed and uses.
The root bark of shaggy-fruited dittany
Nature and flavor:Bitter, it is cold in nature.
Channel tropism:Returns spleen, stomach.
Effect:1. effect:It is clearing heat and detoxicating, it dispels pathogenic wind and remove dampness.It cures mainly:For damp and hot sore, eczema, mange, skin scabies Itch, jaundice with damp-heat pathogen, beriberoid pyretic arthralgia.
Dandelion
Nature and flavor:It is bitter, sweet, it is cold in nature.
Channel tropism:Return liver, stomach.
Effect:It is clearing heat and detoxicating, dampness removing.It cures mainly:For pathopyretic ulcer, jaundice, heat gonorrhea, red eye, swell pain.
The radix paeoniae rubrathe
Nature and flavor:Bitter, cold nature.
Channel tropism:Return liver warp.
Effect:Effect:Clearing heat and cooling blood Lactiflora has clearing heat and cooling blood, promoting blood circulation and removing blood stasis, analgesic.It cures mainly:For blood-head Absurd row, hematemesis hair spot, blood stasis closed, traumatic injury, pathopyretic ulcer, irascibility hot eyes.
Honeysuckle
Nature and flavor:It is sweet in flavor, it is cold in nature.
Channel tropism:Return lung, the heart, stomach, large intestine channel.
Effect 1. is clearing heat and detoxicating, with controlling warm disease from the beginning of body is warm, thirsty, rapid pulse, is often equal with Fructus Forsythiae, Radix Isatidis and uses; Sore carbuncle is from the beginning of red and swollen heat pain is often equal with dandelion, wild chrysanthemum, Chinese violet and uses.2. dispelling wind and heat from the body, with controlling affection of exogenous wind-heat table Card, is often equal with Fructus Forsythiae, peppermint, Lasiosphaera fenzlii and uses.3. removing heat from the blood and relieve diarrhea with toxic-heat and blood stasis is controlled, purslane can be matched, the Chinese bulbul is equally used
Radix Glycyrrhizae
Nature and flavor:It is sweet in flavor, it is mild-natured.
Channel tropism:The thoughts of returning home, spleen, lung, stomach.
Effect:Effect:Glycyrrhiza uralensis fisch is invigorated the spleen and benefited qi, and is moistened the lung and relieve the cough, clearing heat and detoxicating, alleviates analgesic, mitigates pharmacological property. It cures mainly:For weakness of the spleen and the stomach, shortness of breath and fatigue, palpitation and severe palpitation, cough phlegm is few, pathopyretic ulcer, medicine food poisoning, gastral cavity abdomen shoot, four limbs Contraction pain.
The beneficial effects of the invention are as follows:
The present invention fundamentally solves the treatment of wind-heat blood-head psoriasis pustulosa with drug by dialectical.Accelerate skin lesion to repair Again, the scales of skin that peel off is dispelled, antipruritic nti-freckle shortens treatment cycle and other effects.
Present invention treatment psoriasis has following three advantages
First, it treats safer, without side-effects.The most course for the treatment of of treatment of psoriasis is long, is generally cured within the 1-3 months, So doctor selects just to seem extremely important with small drug to treat in poison pair.Because Chinese medicine is the root, stem and leaf of plant mostly, in The ancient Chinese medical classics clinical verification of thousands of years excessively, gradually eliminates toxic Chinese medicine.Such as tetrandra root containing aristolochic acid, caulis aristologhiae manshuriensis, Birthwort, dutchmanspipe root etc. have been eliminated.The Chinese medicine clinically used at present is mostly seldom toxic.So psoriatic is selecting During therapy, the Chinese medicine treatment of preferred Small side effects, safety higher are answered.
2nd, treatment psoriasis can effectively adjust patient's viscera function:For Chinese medicine from psoriasis old complaint, inherent conditioning is dirty Internal organs rather than just simply surface symptoms are dispelled, from inside to outside, could reduce the probability of psoriasis recurrence in this way.In meanwhile The effective antiinflammatories ingredient such as clearing heat and detoxicating drug of medicine is not easy to generate drug resistance to streptococcus.Pharyngeal inflammation can effectively be inhibited, no Toxin is allowed to be again introduced into blood, it can to avoid drug resistance caused by bacterial antibiotic, so as to which psoriasis be inhibited to recur, These are all the reason of Chinese medicine treatment curative effect are higher.
3rd, treatment psoriasis can adjust immune function, improve the immunity of patient body:Drug such as adds gold and silver in prescription Flower formula for clearing heat and removing toxicity, adds Poria cocos to detoxify with clearing heat and promoting diuresis, adds in cornu bubali with clearing away heat,cooling blood and removing toxin, root bark of shaggy-fruited dittany heat-clearing wind-dispelling is added to stop Itch, proved through modern pharmacology research, have the function of to promote body's immunity.Much normal person is pharyngeal inflammation, is Any somebody can induce psoriasis, and somebody does not fall ill, and main cause is exactly immune dysfunction.If immune work( It can be restored, psoriasis would not recur.
Specific embodiment
Embodiment 1
A kind of Chinese medicine for treating psoriasis, is made of the raw material of following weight, 12 grams of Radix Angelicae Sinensis, 10 grams of cicada slough, radix rehmanniae recen 13 Gram, 8 grams of rhizoma anemarrhenae, 8 grams of Radix Salviae Miltiorrhizae, 20 grams of cornu bubali, 8 grams of kuh-seng, windproof 10 grams, 10 grams of Poria cocos, 10 grams of the root bark of shaggy-fruited dittany, dandelion 20 Gram, 8 grams of the radix paeoniae rubrathe, 8 grams of honeysuckle and Radix Glycyrrhizae 3 are restrained into, and preparation method is to decoct.One dose per day.
Embodiment 2
A kind of Chinese medicine for treating psoriasis, is made of the raw material of following weight, 15 grams of Radix Angelicae Sinensis, 12 grams of cicada slough, radix rehmanniae recen 15 Gram, 10 grams of rhizoma anemarrhenae, 10 grams of Radix Salviae Miltiorrhizae, 22 grams of cornu bubali, 10 grams of kuh-seng, windproof 12 grams, 12 grams of Poria cocos, 12 grams of the root bark of shaggy-fruited dittany, dandelion 25 grams, 10 grams of the radix paeoniae rubrathe, 10 grams of honeysuckle and Radix Glycyrrhizae 6 are restrained into, and preparation method is to decoct.One dose per day.
Embodiment 3
A kind of Chinese medicine for treating psoriasis, is made of the raw material of following weight, 13 grams of Radix Angelicae Sinensis, 11 grams of cicada slough, radix rehmanniae recen 14 Gram, 9 grams of rhizoma anemarrhenae, 9 grams of Radix Salviae Miltiorrhizae, 21 grams of cornu bubali, 9 grams of kuh-seng, windproof 11 grams, 11 grams of Poria cocos, 11 grams of the root bark of shaggy-fruited dittany, dandelion 22 Gram, 9 grams of the radix paeoniae rubrathe, 9 grams of honeysuckle and Radix Glycyrrhizae 4 are restrained into, and preparation method is to decoct.One dose per day.
Embodiment 4
A kind of Chinese medicine for treating psoriasis, is made of the raw material of following weight, 12 grams of Radix Angelicae Sinensis, 11 grams of cicada slough, radix rehmanniae recen 14 Gram, 10 grams of rhizoma anemarrhenae, 8 grams of Radix Salviae Miltiorrhizae, 22 grams of cornu bubali, 9 grams of kuh-seng, windproof 10 grams, 12 grams of Poria cocos, 11 grams of the root bark of shaggy-fruited dittany, dandelion 24 Gram, 8 grams of the radix paeoniae rubrathe, 10 grams of honeysuckle and Radix Glycyrrhizae 5 are restrained into, and preparation method is to decoct.One dose per day.
Clinical trial
1.1st, Dermatology Outpatient Department outpatients are screened, are diagnosed as psoriasis vulgaris " " wind-heat blood-heat syndrome ", diagnostic criteria root According to《Surgery of Chinese Medicine》.Clinical manifestation continuously emerges for fash, quickly grows, some drop-wise are presented more, and color is scarlet, and the scales of skin that peel off increases More, acute pruritus, what is grabbed has sieve-like blutpunkte;With mouth parched and tongue scorched, have sore throat, dysphoria is hard and dry, dark urine; Red tongue body moss thin yellow, wiry and rolling pulse or number screen 56 altogether.Exclusion criteria:The systems diseases such as serious cardiovascular, liver kidney and endocrine Disease;It is inscribed within 4 weeks before treatment and has received the patient that systematic treating included hormone, immunosuppressor and retinoid drug;Other classes Psoriasis pustulosa;Pregnant and lactant women.It is randomly divided into five groups.Treatment group 20, man 8, female 12;Age 19-58 Sui puts down Equal 32.5 years old;Course of disease 7-30 days, it is 14 days average.Control group 80, man 25, female 15;It is age 21-54 Sui, 29.5 years old average; Course of disease 7-30 days, it is 20 days average.Not statistically significant (the P of comparing differences such as two groups of ages, gender, the course of disease, state of an illness>0.05), have There is comparativity.
1.2nd, therapy:Sooner or later point 2 warms take decoction of the present invention orally for treatment group, and one one;Control group:Use Xiaoyin Capsule Chinese medicines quasi-word Z200001 10;Shaanxi Mo Mei get pharmaceutical Co. Ltds produce) 5-7,3 times a day.Two groups are treated 2 treatments Journey, ten days courses for the treatment of.Withdraw other drugs during medication, avoid eating the product of the pungent fatness, sweet, thick and oily of seafood.
1.3rd, criterion of therapeutical effect:It is commented according to international psoriatic lesion area severity index (PASI) standards of grading Valency curative effect.
Recovery from illness:PASI integrations decline >=90%, and skin lesion all subsides or only remains a small number of drop damages, and itch disappears;
It is effective:Decline 60%-89%, more than 60% skin lesion recession occasionally has itch;
Effectively:Decline 25%-59%, more than 30% skin lesion recession still has itch;
In vain:Integration declines<25%, skin lesion subsides less than 30% or without improvement, hence it is evident that itch, it is difficult to endure.
Recovery from illness, effective, effectively total calculating is efficient.Follow-up observation is carried out to recovery from illness patient and effective patient, after 6 months Rise 50% when relatively stopping treatment such as PASI integrations to be judged to recur.
2.1 treatment results are as follows:
The pretherapy and post-treatment PASI scorings of 1 patient of table are compared
2 patient outcomes of table compare
Two groups of data compare to be examined using x2, P<0.05 is statistically significant for difference.
Follow-up half a year recurrence after 3 two groups of patient's treatments of table
2.2nd, adverse reaction and safety detection:4 groups of embodiment has 1 loose stools occur, and 1 slight upper abdomen occurs in control group Portion is uncomfortable, does not influence further to treat, pretherapy and post-treatment blood, routine urinalysis, the detection of hepatic and renal function are showed no obvious abnormalities.
It can be seen that from the data of above table and take traditional Chinese herbal decoction treatment blood-head psoriasis pustulosa provided by the invention, have Xiao Shuai ﹙ recoveries from illness plus effective it is substantially better than control group added with Xiao ﹚;Adverse reaction rate and performance no significant difference;Recovery from illness, effective patient Half a year recurrence rate is significantly lower than control group.
Clinical case
Short Term Clinical cures psoriasis vulgaris 96, into the departure date 28, resting stage 47.
Model case
Wang Su plums female 39 years old, psoriasis vulgaris
Medical history:It is skin maculopapule, more than 9 years scratchy, it is originally inflammatory red papules, about grain grain is to mung bean size, with hair Exhibition, which gradually expands, is fused into brownish red patch, clear border, around there is inflammatory blush, and substrate infiltration is apparent, the drying of overlying multilayer The silvery white scales of skin that peel off, the gently scraper surface scales of skin that peel off is lower for one layer of light red shinny semitransparent thin film;Light scraping thin film again occurs It is dispersed in small blutpunkte.Skin lesion is on the increase, scorching hot scratchy from head to foot, and autumn aggravates, and To Be Protected from Heat, dark urine, dry and hard excrement.Tongue is red, Moss thin yellow, slippery and rapid pulse.Come me section to go to a doctor, be diagnosed as " psoriasis vulgaris " " wind-heat blood-heat syndrome ", give 10 doses of this prescription decoction, Carry out institute's further consultation scales of skin that peel off to subside, papule disappears, and scorching hot scratchy symptom disappears;10 doses of decoction is given again, and symptom completely disappears.After 1 year Follow-up is without recurrence.
Finally illustrate, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, this field is common Other modifications or equivalent replacement that technical staff makes technical scheme of the present invention, without departing from technical solution of the present invention Spirit and scope, be intended to be within the scope of the claims of the invention.

Claims (4)

1. a kind of Chinese medicine for treating psoriasis, which is characterized in that be made of the raw material of following weight, 12-15 grams of Radix Angelicae Sinensis, cicada slough 10-12 grams, 13-15 grams of radix rehmanniae recen, 8-10 grams of rhizoma anemarrhenae, 8-10 grams of Radix Salviae Miltiorrhizae, 20-22 grams of cornu bubali, 8-10 grams of kuh-seng, windproof 10- 12 grams, 10-12 grams of Poria cocos, 10-12 grams of the root bark of shaggy-fruited dittany, 20-25 grams of dandelion, 8-10 grams of the radix paeoniae rubrathe, 8-10 grams of honeysuckle and Radix Glycyrrhizae 3-6 Restrain into, preparation method is to decoct.
2. the Chinese medicine for the treatment of psoriasis according to claim 1, which is characterized in that it is made of the raw material of following weight, when Return 12 grams, 10 grams of cicada slough, 13 grams of radix rehmanniae recen, 8 grams of rhizoma anemarrhenae, 8 grams of Radix Salviae Miltiorrhizae, 20 grams of cornu bubali, 8 grams of kuh-seng, windproof 10 grams, Poria cocos 10 Gram, 10 grams of the root bark of shaggy-fruited dittany, 20 grams of dandelion, 8 grams of the radix paeoniae rubrathe, 8 grams of honeysuckle and Radix Glycyrrhizae 3 restrain into, and preparation method is to decoct.
3. the Chinese medicine for the treatment of psoriasis according to claim 1, which is characterized in that it is made of the raw material of following weight, when Return 15 grams, 12 grams of cicada slough, 15 grams of radix rehmanniae recen, 10 grams of rhizoma anemarrhenae, 10 grams of Radix Salviae Miltiorrhizae, 22 grams of cornu bubali, 10 grams of kuh-seng, windproof 12 grams, Fu 12 grams of Siberian cocklebur, 12 grams of the root bark of shaggy-fruited dittany, 25 grams of dandelion, 10 grams of the radix paeoniae rubrathe, 10 grams of honeysuckle and Radix Glycyrrhizae 6 are restrained into, and preparation method is pan-fried It boils.
4. the Chinese medicine for the treatment of psoriasis according to claim 1, which is characterized in that it is made of the raw material of following weight, when Return 14 grams, 11 grams of cicada slough, 14 grams of radix rehmanniae recen, 9 grams of rhizoma anemarrhenae, 9 grams of Radix Salviae Miltiorrhizae, 21 grams of cornu bubali, 9 grams of kuh-seng, windproof 11 grams, Poria cocos 11 Gram, 11 grams of the root bark of shaggy-fruited dittany, 23 grams of dandelion, 9 grams of the radix paeoniae rubrathe, 9 grams of honeysuckle and Radix Glycyrrhizae 5 restrain into, and preparation method is to decoct.
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CN109260288A (en) * 2018-11-19 2019-01-25 吉林大学 A kind of drug and preparation method thereof for treating psoriasis
CN109393094A (en) * 2018-10-19 2019-03-01 王选庆 A kind of Tea containing traditional Chinese medicine for treating psoriasis

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