CN103735921A - Medicine for treating urethritis and preparation method thereof - Google Patents
Medicine for treating urethritis and preparation method thereof Download PDFInfo
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- CN103735921A CN103735921A CN201410040675.9A CN201410040675A CN103735921A CN 103735921 A CN103735921 A CN 103735921A CN 201410040675 A CN201410040675 A CN 201410040675A CN 103735921 A CN103735921 A CN 103735921A
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Abstract
The invention discloses a medicine for treating urethritis and a preparation method thereof. The medicine mainly comprises the following components according to a certain weight ratio: rhizoma alismatis, bamboo leaves, plantain seeds, taraxacum, lonicera japonica, talcum, cogongrass rhizome, isatis root, glycyrrhiza, gardenia and the like. The medicine of the invention has the functions of clearing heat and detoxifying and nourishing yin to reduce pathogenic fire, operates quickly and has good curative effect and no side effect in treating urethritis.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of urethritis and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Urethritis refers to the inflammation of urethral mucosa, is a kind of commonly encountered diseases, is more common in women, is divided into clinically acute and chronic, nonspecific urethritis and gonococcal urethritis, mostly is pathogenic bacterium and drives in the wrong direction and invade urethra and cause.Because current Western medicine cannot effectively be treated urethritis, so there is great demand to the Chinese medicine of rapid, effective treatment urethritis in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment urethritis, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment urethritis.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Rhizoma Alismatis, Folium Bambusae, Semen Plantaginis, Herba Taraxaci, Flos Lonicerae, Talcum, Rhizoma Imperatae, Radix Isatidis, Radix Glycyrrhizae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, Cortex Phellodendri, Herba Lysimachiae, Flos cercis chinensis, Herba Violae, Radix Sanguisorbae medicine to combine preparation; make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat urethritis.Wherein select Rhizoma Alismatis to be because its nature and flavor are sweet, cold, enter urinary bladder channel, there is diuretic, eliminating dampness by diuresis, the function expelling the heat-evil, controls dysuria, and edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Selecting Folium Bambusae is because its property slightly sweet flavor, cold, enters the heart, lung, gallbladder, stomach warp, has clearing heat and relieving fidgetness, and the function of the diuresis of promoting the production of body fluid controls that calentura is tired drinks, and little youngster shies Epilepsy, and cough with dyspnea is told nosebleed, flushed complexion, oliguria with reddish urine, erosion of the oral mucosa tongue boil.Select Semen Plantaginis to be because its nature and flavor are sweet, cold, enter kidney, urinary bladder channel, there is diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Select Herba Taraxaci to be because its property bitter but sweet flavor is cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Flos Lonicerae to be because its nature and flavor are sweet, cold, enter lung, stomach warp, there is heat clearing away, the function of removing toxic substances, controls epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Select Talcum to be because its nature and flavor are sweet, light, cold, return bladder, lung, stomach warp, there is inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing, the function of damp eliminating expelling summer-heat, controls pyretic stranguria, stranguria caused by urinary stone, urinates hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea, external treatment eczema, eczema, miliaria.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae, enters lung, stomach, small intestine meridian, has removing heat from blood, hemostasis, and heat clearing away, the function of diuresis, controls calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select Radix Isatidis to be because its nature and flavor are bitter, cold, enter liver, stomach blood system, there is heat clearing away, removing toxic substances, the function of removing heat from blood, controls influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, pyretic toxicity is sent out speckle, and coma is told nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, there is heat clearing away, pathogenic fire purging, the function of removing heat from blood, controls calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Radix Et Rhizoma Rhei to be because its nature and flavor are bitter, cold, enter stomach, large intestine, liver footpath, have the poison of purging heat, removing mass is stagnant, the function of clots absorbing blood, controls excess-heat constipation, and delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and the function of subduing inflammation, controls gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe in invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select Cortex Phellodendri to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, there is nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Herba Lysimachiae to be because its nature and flavor toil is cool, have heat clearing away, diuresis, antitussive, detumescence, the function of removing toxic substances, the subcutaneous ulcer of harnessing the Yellow River, edema, vesical calculus, malaria, lung abscess, cough, spits blood, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, infantile malnutrition ， Jing Epilepsy, carbuncle, skin ulcer tinea, eczema.Select Flos cercis chinensis to be because its nature and flavor are worked hard, have clearing away heat and cooling blood, go the function of wind removing toxic substances, dispelling the wind and dampness pathogens bones and muscles pain.Select Herba Violae to be because its nature and flavor are bitter, cold, enter the heart, Liver Channel, there is clearing away heat-damp and promoting diuresis, the function of removing toxic substances and promoting subsidence of swelling, controls furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Select Radix Sanguisorbae to be because its nature and flavor picric acid is cold, enter liver, large intestine channel, have cooling blood for hemostasis, the function of heat-clearing and toxic substances removing, controls haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Rhizoma Alismatis 10-20 gram of Folium Bambusae 12-20 gram of Semen Plantaginis 10-18 gram
Herba Taraxaci 12-22 gram of Flos Lonicerae 10-20 gram of Talcum 8-18 gram
Rhizoma Imperatae 15-25 gram of Radix Isatidis 12-20 gram of Radix Glycyrrhizae 5-10 gram
Fructus Gardeniae 8-18 gram of Radix Et Rhizoma Rhei 8-16 gram of Radix Achyranthis Bidentatae 10-20 gram
Cortex Phellodendri 8-18 gram of Herba Lysimachiae 10-20 gram of Flos cercis chinensis 10-20 gram
Herba Violae 12-22 gram of Radix Sanguisorbae 8-18 gram
Be preferably
15 grams of 15 grams of Semen Plantaginiss of 15 grams of Folium Bambusaes of Rhizoma Alismatis
15 grams, 15 grams of Talcums of 15 grams of Flos Loniceraes of Herba Taraxaci
6 grams, 15 grams of Radix Glycyrrhizaes of 20 grams of Radix Isatidis of Rhizoma Imperatae
12 grams of 10 grams of Radix Achyranthis Bidentataes of 15 grams of Radix Et Rhizoma Rhei of Fructus Gardeniae
15 grams of 15 grams of Flos cercis chinensiss of 10 grams of Herba Lysimachiaes of Cortex Phellodendri
15 grams of 15 grams of Radix Sanguisorbaes of Herba Violae
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;
2, Folium Bambusae: choose clean impurity, except destemming leaf, dry;
3, Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
4, Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
5, Flos Lonicerae: sieve removes silt, chooses clean impurity;
6, Talcum: get crude drug, remove impurity, clean, pound into fritter;
7, Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dries, the clean chip of winnowing with a dustpan;
8, Radix Isatidis: choose clean impurity, clean, run through, section, dries;
9, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, airing;
10, Fructus Gardeniae: sieve dedust bits, choose decontamination, pulverize and sieve or cut off two ends;
11, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;
12, Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
13, Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding, dry;
14, Herba Lysimachiae: choose clean impurity, sieve dedust bits, dry;
15, Flos cercis chinensis: choose clean impurity, dry;
16, Herba Violae: choose clean impurity, water washes away earth, cutting is dried;
17, Radix Sanguisorbae: choose decontamination, wash, slightly soak, run through, be cut into sheet, dry.
Two, preparation
1, the Rhizoma Alismatis of described weight, Folium Bambusae, Semen Plantaginis, Herba Taraxaci, Flos Lonicerae, Talcum (pack cloth bag into or use cloth bag), Rhizoma Imperatae, Radix Isatidis, Radix Glycyrrhizae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, Cortex Phellodendri, Herba Lysimachiae, Flos cercis chinensis, Herba Violae, Radix Sanguisorbae are decocted with water twice; add for the first time 6 times of amounts of water; intense fire decocts boiling 10 minutes; use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time.
2, the medicinal residues after filtering are for the first time added to 5 times of amounts of water, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time.
3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 3 doses and takes.
Medicine of the present invention has heat-clearing and toxic substances removing, and the function of nourishing YIN to lower pathogenic fire is used for the treatment of urethritis instant effect, good effect.By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
Frequent micturition, burning on urination and hematuria, acute stage male can have urethral secretions, start as mucus, after have volume purulent secretion; Women is rare secretions, transfers to when chronic and show as urethral irritation and the discomfort of urinating, and urethral secretions reduces, and is thin serosity shape, and during acute attack, suprapubic region and perineal position have dull pain, and visible urethral orifice is rubescent, has secretions.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, every day potion, the morning, noon and afternoon service once, and take continuously 7 days.
4, efficacy assessment standard
Effective: the recovery from illness of urethritis symptom, recovers normal.
Take a turn for the better: urethritis symptom alleviates, progressively take a turn for the better.
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy urethritis patient of the present invention 100 examples, effective 83 examples of result, obvious effective rate is 83%, 6 examples that take a turn for the better, and improvement rate is 6%, invalid 11 examples, total effective rate is 89%.
Claims (3)
1. a medicine for the treatment of urethritis, is characterized in that: it is to be made by the crude drug in following weight range:
Rhizoma Alismatis 10-20 gram of Folium Bambusae 12-20 gram of Semen Plantaginis 10-18 gram
Herba Taraxaci 12-22 gram of Flos Lonicerae 10-20 gram of Talcum 8-18 gram
Rhizoma Imperatae 15-25 gram of Radix Isatidis 12-20 gram of Radix Glycyrrhizae 5-10 gram
Fructus Gardeniae 8-18 gram of Radix Et Rhizoma Rhei 8-16 gram of Radix Achyranthis Bidentatae 10-20 gram
Cortex Phellodendri 8-18 gram of Herba Lysimachiae 10-20 gram of Flos cercis chinensis 10-20 gram
Herba Violae 12-22 gram of Radix Sanguisorbae 8-18 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
15 grams of 15 grams of Semen Plantaginiss of 15 grams of Folium Bambusaes of Rhizoma Alismatis
15 grams, 15 grams of Talcums of 15 grams of Flos Loniceraes of Herba Taraxaci
6 grams, 15 grams of Radix Glycyrrhizaes of 20 grams of Radix Isatidis of Rhizoma Imperatae
12 grams of 10 grams of Radix Achyranthis Bidentataes of 15 grams of Radix Et Rhizoma Rhei of Fructus Gardeniae
15 grams of 15 grams of Flos cercis chinensiss of 10 grams of Herba Lysimachiaes of Cortex Phellodendri
15 grams of 15 grams of Radix Sanguisorbaes of Herba Violae.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;
(2) Folium Bambusae: choose clean impurity, except destemming leaf, dry;
(3) Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
(4) Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
(5) Flos Lonicerae: sieve removes silt, chooses clean impurity;
(6) Talcum: get crude drug, remove impurity, clean, pound into fritter;
(7) Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dries, the clean chip of winnowing with a dustpan;
(8) Radix Isatidis: choose clean impurity, clean, run through, section, dries;
(9) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, airing;
(10) Fructus Gardeniae: sieve dedust bits, choose decontamination, pulverize and sieve or cut off two ends;
(11) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;
(12) Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
(13) Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding, dry;
(14) Herba Lysimachiae: choose clean impurity, sieve dedust bits, dry;
(15) Flos cercis chinensis: choose clean impurity, dry;
(16) Herba Violae: choose clean impurity, water washes away earth, cutting is dried;
(17) Radix Sanguisorbae: choose decontamination, wash, slightly soak, run through, be cut into sheet, dry;
(2) preparation
(1) Rhizoma Alismatis of described weight, Folium Bambusae, Semen Plantaginis, Herba Taraxaci, Flos Lonicerae, Talcum (pack cloth bag into or use cloth bag), Rhizoma Imperatae, Radix Isatidis, Radix Glycyrrhizae, Fructus Gardeniae, Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, Cortex Phellodendri, Herba Lysimachiae, Flos cercis chinensis, Herba Violae, Radix Sanguisorbae are decocted with water twice, add for the first time 6 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time;
(2) medicinal residues after filtering are for the first time added to 5 times of amounts of water, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time;
(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 3 doses and takes.
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| CN201410040675.9A CN103735921B (en) | 2014-01-28 | 2014-01-28 | A kind of medicine for the treatment of urethritis and preparation method thereof |
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| CN103735921B CN103735921B (en) | 2016-04-06 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104225301A (en) * | 2014-08-30 | 2014-12-24 | 济南伟传信息技术有限公司 | Traditional Chinese medicine for treating urinary system infection |
| CN104984153A (en) * | 2015-08-07 | 2015-10-21 | 苏州神林堂中医药研究所 | Traditional Chinese medicine composition treating urethritis and preparation method and application |
| CN105920398A (en) * | 2016-05-13 | 2016-09-07 | 刘秀英 | Traditional Chinese medicine for treating strangury |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152472A (en) * | 2007-09-17 | 2008-04-02 | 尹克山 | Traditional Chinese medicine for treating pregnancy complicated with urinary tract infection |
| CN101366896A (en) * | 2007-08-13 | 2009-02-18 | 李继田 | Traditional Chinese medicine for treating chronic prostatitis and preparation method thereof |
-
2014
- 2014-01-28 CN CN201410040675.9A patent/CN103735921B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101366896A (en) * | 2007-08-13 | 2009-02-18 | 李继田 | Traditional Chinese medicine for treating chronic prostatitis and preparation method thereof |
| CN101152472A (en) * | 2007-09-17 | 2008-04-02 | 尹克山 | Traditional Chinese medicine for treating pregnancy complicated with urinary tract infection |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104225301A (en) * | 2014-08-30 | 2014-12-24 | 济南伟传信息技术有限公司 | Traditional Chinese medicine for treating urinary system infection |
| CN104984153A (en) * | 2015-08-07 | 2015-10-21 | 苏州神林堂中医药研究所 | Traditional Chinese medicine composition treating urethritis and preparation method and application |
| CN105920398A (en) * | 2016-05-13 | 2016-09-07 | 刘秀英 | Traditional Chinese medicine for treating strangury |
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